Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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p-nitrosophenol reduction by liver cytosol from adh-positive and -negative deermice (peromyscus maniculatus). | liver cytosolic fractions are known to catalyze the reduction of certain c-nitroso compounds to their corresponding hydroxylamines and amines. alcohol dehydrogenase (adh), nad(p)h:quinone oxidoreductase, and xanthine and aldehyde oxidases have been implicated as c-nitroso reductases. to probe the role of these cytosolic enzymes in the reduction of c-nitroso compounds we have studied the effects of classical inhibitors of these enzymes on the ability of liver cytosolic fractions from adh+ and adh ... | 1995 | 7532387 |
hantavirus pulmonary syndrome: report of four alberta cases. | four alberta cases of hantavirus pulmonary syndrome are reported. three cases required intensive care, with one experiencing a fulminant course resulting in death. a fourth case with milder illness was identified after epidemiological investigations. ribavirin was used in one patient who experienced a successful outcome. a recent open label trial has not supported the efficacy of this drug. the epidemiology of peromyscus maniculatus, the primary rodent host, and the clinical features of this syn ... | 1995 | 22514394 |
toxicological foundations of ecological risk assessment: biomarker development and interpretation based on laboratory and wildlife species. | ecological risk assessments based on chemical residue analysis and species demographics tend to ignore the bioavailability and bioaccumulation of the chemicals of concern. this study describes the incorporation of mechanistically based biomarkers into an ecological risk assessment of a poly-cyclic aromatic hydrocarbon (pah)-contaminated site. a combination of soil residue analysis, tissue residue analysis, biomarkers in one-site trapped animals and biomarkers in animals confined to enclosures wa ... | 1994 | 7713037 |
role of gonadal steroids and inhibitory photoperiod in regulating body weight and food intake in deer mice (peromyscus maniculatus). | we investigated the role of declining daylength and gonadal steroids on body weight and food intake in male deer mice (peromyscus maniculatus). this species was chosen for study because individual males display different reproductive responses to inhibitory daylength. about one-third of all mice exposed to short days undergo testicular regression and exhibit reduced circulating levels of luteinizing hormone and testosterone (reproductive responsive males). in contrast, testicular function and ci ... | 1994 | 8073049 |
day length affects immune cell numbers in deer mice: interactions with age, sex, and prenatal photoperiod. | the extent to which day length affects immune function was examined in the present study. three goals were pursued: 1) to confirm and extend the observation that the immune systems of adult deer mice (peromyscus maniculatus) are responsive to changes in photoperiod, 2) to examine the development of the photoperiod-associated changes in immune function, and 3) to discover whether photoperiodic information transmitted to the young during gestation influences immune function. in experiment 1, adult ... | 1994 | 8067473 |
influence of mustelid semiochemicals on population dynamics of the deer mouse (peromyscus maniculatus). | the influence of mustelid anal-gland compounds on population dynamics of the deer mouse (peromyscus maniculatus) was investigated. densities of deer mice were not found to be significantly different between treated and control areas. however, on average, numbers of deer mice were lower on treated areas following the july treatments of 1991 and 1992. survival rates appeared to be lower and more erratic on treated than control areas in 1991; however, there were no statistically significant differe ... | 1994 | 24242120 |
sexually dimorphic spatial learning varies seasonally in two populations of deer mice. | spatial learning in photoperiodically induced breeding (reproductive) and non-breeding (non-reproductive) adult male and female deer mice (peromyscus maniculatus) was examined in a morris water-maze task. sexually mature, adult male and female deer mice that were derived from either a mainland population (p. m. artemisiae) or an island population (p. m. angustus) were required to learn the spatial position of a hidden, submerged platform in a water maze. deer mice were tested either during the b ... | 1994 | 8173954 |
etiology and epidemiology of the four corners hantavirus outbreak. | in may and june 1993, a handful of previously healthy residents of rural areas in the four corners region of the southwestern united states died of acute unexplained respiratory distress, later diagnosed as hantavirus pulmonary syndrome. their illnesses were characterized most prominently by a prodrome of fever and myalgias, followed by thrombocytopenia, the presence of immature white blood cells on the peripheral smear, and catastrophic respiratory decline associated with the sudden onset of no ... | 1994 | 7866656 |
photoperiodic effects on tumor development and immune function. | seasonal changes in adaptations associated with winter coping strategies have been frequently studied. central among the suite of energy-saving, winter-coping strategies is the suspension of reproductive activities. the inhibition of reproduction by nontropical rodents is mediated by daylength changes. although balanced annual energy budgets are critical, survival and subsequent reproductive success also require avoiding predators, illness, and early death. because the stressors of winter could ... | 1994 | 7772792 |
distribution of borrelia burgdorferi in host mice in pennsylvania. | host mice (peromyscus leucopus and peromyscus maniculatus) were sampled throughout the state of pennsylvania to determine the geographical and ecological distribution of the lyme disease spirochete borrelia burgdorferi. all 67 counties of the state were sampled. a total of 1,619 mice were captured from a total of 157 sites during the period 1990 to 1993 for an overall capture rate of 29.69%. a total of 112 (6.92%) isolations of b. burgdorferi were made. the distribution of isolations revealed th ... | 1994 | 7814489 |
natural and experimental borrelia burgdorferi infections in woodrats and deer mice from california. | sequestration of spirochetes and concurrent histopathologic lesions were evaluated in tissues of borrelia burgdorferi-infected dusky-footed woodrats (neotoma fuscipes) and deer mice (peromyscus maniculatus). rodents were either wild-caught and naturally infected or were experimentally infected by tick bite, by intramuscular (i.m.) injection of cultured spirochetes, or by i.m. injection of tick suspensions. samples of host tissues, including skin, blood, ear, brain, eye, heart, lung, liver, splee ... | 1994 | 7933283 |
genetic evidence for a hantavirus enzootic in deer mice (peromyscus maniculatus) captured a decade before the recognition of hantavirus pulmonary syndrome. | to determine if the emergence of hantavirus pulmonary syndrome in the united states was a consequence of recent amino-acid altering mutations and/or genetic reassortment with pathogenic hantaviruses, we examined lung and spleen tissues from seropositive deer mice trapped in august 1983 in mono county, california, for hantaviral rna by reverse transcriptase-directed polymerase chain reaction. alignment and comparison of 1485 nucleotides of the s and m genomic segments enzymatically amplified from ... | 1994 | 7941323 |
bioavailability of metals and arsenic to small mammals at a mining waste-contaminated wetland. | in support of a baseline ecological risk assessment evaluating the impacts of mining wastes at the milltown reservoir sediments superfund site in montana, a food chain transfer analysis was performed for resident small mammals. deer mice (peromyscus maniculatus) and meadow voles (microtus pennsylvanicus) were trapped from a 200 a portion of a mixed upland and palustrine wetland, and concentrations of as, cd, cu, pb, and zn in carcass, liver, kidney, and testes were quantified. concurrent to smal ... | 1994 | 8024321 |
vector competence of ixodes pacificus and dermacentor occidentalis (acari: ixodidae) for various isolates of lyme disease spirochetes. | the vector competence of the western black-legged tick, ixodes pacificus cooley & kohls, and the pacific coast tick, dermacentor occidentalis marx, for the lyme disease spirochete (borrelia burgdorferi johnson, schmid, hyde, steigerwalt & brenner) was compared. rabbits, hamsters, and the deer mouse, peromyscus maniculatus (wagner), were injected with cultured spirochetes or infected tick-suspensions, or were fed upon by spirochete-infected ticks. five of seven isolates used as inocula were reiso ... | 1994 | 8057316 |
isolation of the causative agent of hantavirus pulmonary syndrome. | investigation of a recent outbreak of acute respiratory illness in the southwestern united states resulted in the recognition of a new disease, hantavirus pulmonary syndrome (hps) with high mortality. different animals and cell lines were used in attempts to isolate the causative agent. a previously unknown hantavirus was passaged in laboratory-bred deer mice, recovered from lung tissues of a deer mouse, peromyscus maniculatus, and propagated in the e6 clone of vero cells. virus antigen was read ... | 1994 | 8059907 |
comparison of chromosomal distribution of a retroposon (line) and a retrovirus-like element mys in peromyscus maniculatus and p. leucopus. | chromosomal distribution for two interspersed elements (lines and mys) that are thought to have established their chromosomal position primarily by transposition was compared between two species of deer mice (peromyscus leucopus and p. maniculatus). both lines and mys generally produced an autosomal banding pattern reflective of g-bands and both hybridized preferentially to the sex chromosomes. the pattern on the long arm of the x was unique for each, with mys reflecting the g-bands (four bands ... | 1994 | 8069462 |
coat color genetics of peromyscus: iv. variable white, a new dominant mutation in the deer mouse. | the variable white mutation arose spontaneously in 1983 within a laboratory stock of wild-type deer mice (peromyscus maniculatus). the original mutant animal was born to a wild-type pair that had previously produced several entirely wild-type litters. other variable white animals were bred from the initial individual. variable white deer mice exhibit extensive areas of white on the head, sides, and tail. usually a portion of pigmented pelage occurs dorsally and on the shoulders, but the extent o ... | 1994 | 8120357 |
[pulmonary syndrome caused by hantavirus--a new syndrome with high mortality]. | an outbreak of a previously unknown, severe infectious disease with rapidly fatal respiratory distress was reported from southwestern usa in may 1993. the case fatality rate was about 60 per cent. using pcr hantavirus rna could be demonstrated in lungs and other tissues from patients. mice and others rodents, e g peromyscus maniculatus, were shown to be a reservoir of the virus. this new virus, designated four corner virus, has been further characterised and seems to be closely related to puumal ... | 1994 | 8139902 |
h-2t24 and pemat24: orthologous expressed mhc class ib genes from mouse and peromyscus maniculatus. | 1994 | 8188318 | |
serologic and genetic identification of peromyscus maniculatus as the primary rodent reservoir for a new hantavirus in the southwestern united states. | an outbreak of hantavirus pulmonary syndrome (hps) in the southwestern united states was etiologically linked to a newly recognized hantavirus. knowledge that hantaviruses are maintained in rodent reservoirs stimulated a field and laboratory investigation of 1696 small mammals of 31 species. the most commonly captured rodent, the deer mouse (peromyscus maniculatus), had the highest antibody prevalence (30%) to four hantavirus antigens. antibody also was detected in 10 other species of rodent and ... | 1994 | 8195603 |
comparative toxicity of azinphos-methyl to house mice, laboratory mice, deer mice, and gray-tailed voles. | a laboratory toxicity study on house mice and laboratory mice (mus musculus), gray-tailed voles (microtus canicaudus), and deer mice (peromyscus maniculatus) was conducted as part of a comprehensive laboratory and field study to field validate laboratory-based risk assessment of pesticides. the single dose oral ld50 for the organophosphorus insecticide azinphos-methyl (guthion) was 10, 11, 32, and 48 mg/kg body weight in wild house mice, laboratory mice, gray-tailed voles, and deer mice, respect ... | 1994 | 8198427 |
molecular basis of the alcohol dehydrogenase-negative deer mouse. evidence for deletion of the gene for class i enzyme and identification of a possible new enzyme class. | the molecular basis of the alcohol dehydrogenase (adh)-negative deer mouse (peromyscus maniculatus) has been investigated. several classes of mammalian adhs have been recognized based upon biochemical and structural properties. adh cdna clones identified by hybridization to a mouse class i adh cdna clone were obtained from a deer mouse adh-positive liver cdna library. this cdna has been identified as being a class i sequence and represents the deer mouse adh-1 gene. an additional cdna sequence i ... | 1993 | 8227055 |
genetic identification of a hantavirus associated with an outbreak of acute respiratory illness. | a mysterious respiratory illness with high mortality was recently reported in the southwestern united states. serologic studies implicated the hantaviruses, rodent-borne rna viruses usually associated elsewhere in the world with hemorrhagic fever with renal syndrome. a genetic detection assay amplified hantavirus-specific dna fragments from rna extracted from the tissues of patients and deer mice (peromyscus maniculatus) caught at or near patient residences. nucleotide sequence analysis revealed ... | 1993 | 8235615 |
coat color genetics of peromyscus: ii. tan streak--a new recessive mutation in the deer mouse, p. maniculatus. | the first mutant tan streak deer mice appeared in the initial laboratory-bred generation of a stock of peromyscus maniculatus nubiterrae collected in macon county, north carolina. laboratory progeny from the original animals were bred and mated among themselves and to wild-type individuals. the tan streak phenotype is characterized by nearly complete absence of coat pigmentation, except for a pale tan patch or narrow stripe extending mid-dorsally posteriorly from the head. the band is frequently ... | 1993 | 8340619 |
enteral and parenteral phases of trichinella nativa and trichinella pseudospiralis in the deer mouse, peromyscus maniculatus. | trichinella nativa and trichinella pseudospiralis infections in a wild rodent host, the deer mouse (peromyscus maniculatus), were characterized. forty-six percent of 400 inoculated t. nativa were recovered on day 4 postinoculation (pi); 77% and 23% were found in the small and large intestines, respectively. thirty-one percent of the worms recovered on day 4 remained in the large intestine beyond day 20 pi. worms were embedded in the mucosa of the small intestine, cecum, and colon. females recove ... | 1993 | 8410546 |
update: hantavirus pulmonary syndrome--united states, 1993. | a unique hantavirus has been identified as the cause of the outbreak of respiratory illness (hantavirus pulmonary syndrome [hps]) first recognized in the southwestern united states in may 1993. the habitat of the principal rodent reservoir for this virus, peromyscus maniculatus (deer mouse), extends throughout most of the united states except the southeast. through october 21, 1993, hps has been confirmed in 42 persons reported to cdc from 12 states (figure 1). this report summarizes major clini ... | 1993 | 8413170 |
growth regulation in peromyscus species hybrids: a test for mitochondrial-nuclear genomic interaction. | interspecific hybridization of peromyscus maniculatus (deer mouse) and p. polionotus (oldfield mouse) is accompanied by pronounced size differences between reciprocal f1 animals beginning in the fetus and continuing throughout life. since the mitochondrial genome is inherited through the maternal line in peromyscus, we tested the hypothesis that increased disparity between the species sources of mitochondrial and nuclear genomes within animals would exaggerate the reciprocal size effects through ... | 1993 | 8495994 |
competence of peromyscus maniculatus (rodentia: cricetidae) as a reservoir host for borrelia burgdorferi (spirochaetares: spirochaetaceae) in the wild. | although capable of maintaining and transmitting borrelia burgdorferi johnson, schmidt, hyde, steigerwalt & brenner, the causative spirochete of lyme disease, in the laboratory, the specific ability of deer mice, peromyscus maniculatus le conte, to support this zoonosis has not been established. demonstration that p. maniculatus is a competent reservoir host in the wild would indicate that the spread of lyme disease is not limited to the range of the primary reservoir host, p. leucopus rafinesqu ... | 1993 | 8510121 |
dehydrogenase-dependent metabolism of alcohols in gastric mucosa of deer mice lacking hepatic alcohol dehydrogenase. | deer mice (peromyscus maniculatus) lacking hepatic alcohol dehydrogenase (adh) have been used as a model for studies of ethanol elimination catalysed by non-adh systems like catalase and cytochrome p450. however, in an in vivo study on these animals (adh- deer mice), we detected reversibility in the oxidation of [2h]ethanol, indicating that a major part of the ethanol elimination was due to a dehydrogenase (norsten et al., j biol chem 264: 5593-5597, 1989). in the present investigation, we found ... | 1993 | 8512583 |
regional analysis of 5-ht1a receptors in two species of peromyscus. | two species of deer-mice, peromyscus maniculatus (p. man) and peromyscus leucopus (p. leu), were compared for differences in 5-hydroxytryptamine1a (5-ht1a) receptor number and affinity. both species enter into torpor; however, p. man enters spontaneous torpor with a higher frequency and for a longer duration than p. leu. further, compared to p. leu a higher percentage of p. man exhibit daily torpor. deer mice can be induced to enter torpor by a reduction in food supply, shortened photoperiods, a ... | 1993 | 8516353 |
sex differences in the antinociceptive effects of the enkephalinase inhibitor, sch 34826. | the effects of endogenous opioid peptides are limited by proteolytic enzymes such as endopeptidase 24.11 ("enkephalinase"), which cleaves the gly-phe bonds in met- and leu-enkephalin. sch 34826 [(s)-n-[n-[1-[(2,2-dimethyl-1,3-dioxolan-4- yl)methoxy]carbonyl]-2-phenylethyl]-l-phenyl-alanine-b-alanine] is a potent, highly specific, enkephalinase inhibitor that has marked analgesic effects in laboratory rodents. the present study compared the effects of sch 34826 on nociception and restraint stress ... | 1993 | 8309954 |
diurnal rhythms of 5-ht1a and 5-ht2 receptor binding in euthermic and torpor prone deermice, peromyscus maniculatus. | deermice display both spontaneous and induced daily torpor bouts, attaining minimum body temperatures of 15-20 degrees c. there is evidence that brain serotonin may be involved in the initiation and/or maintenance of torpor. inhibition of serotonin [5-hydroxytryptamine (5-ht)] synthesis markedly reduces the duration and depth of torpor. because a certain percentage of deermice will not enter torpor under any circumstances, we were able to compare 5-ht receptor subtypes in deermice that readily e ... | 1993 | 8415817 |
season affects tolerance of cohabitation by deer mice. | we measured the resting metabolic rates of peromyscus maniculatus for 7 days before and 7 days following forced pairing in order to determine whether seasonal light cycles influenced the rates of behavioral and metabolic habituation of deer mice to cohabitation. we had earlier shown that winter photoperiod and/or huddling results in lower resting metabolic rates and core temperatures of deer mice. seasonal photoperiods were simulated by conditioning wild-caught mice to 24-h light cycles with dif ... | 1993 | 8451332 |
winter adaptations of male deer mice (peromyscus maniculatus) and prairie voles (microtus ochrogaster) that vary in reproductive responsiveness to photoperiod. | individuals of many nontropical rodent species restrict breeding to the spring and summer. seasonal reproductive quiescence putatively reflects the energetic incompatibility of breeding and thermoregulatory activities. however, so-called "out-of-season" breeding occurs in virtually all rodent populations examined, suggesting that the incompatibility can be resolved. both reproductive inhibition and development of energy-saving adaptations are mediated by environmental photoperiod, but some indiv ... | 1993 | 8280911 |
effect of reproductive function on cold tolerance in deer mice. | thermoregulatory responses were evaluated in male deer mice (peromyscus maniculatus nebrascensis) after exposure to short photoperiod and either warm or cold ambient temperature (t(a)). deer mice were chosen for this study because males exhibit differential reproductive responses to short day length (sd); this difference has a genetic basis, and both phenotypes are found within natural breeding populations. deer mice undergoing sd-induced gonadal regression significantly improved their cold limi ... | 1992 | 1415794 |
the effects of feeding triiodothyronine on reproductively inhibited prairie deermice (peromyscus maniculatus bairdii) from laboratory populations. | 1. two reproductively inhibited populations were given 250 ng triiodothyronine (t3) per gram of food for 35 days to elevate the reduced serum thyroid hormone concentration previously demonstrated in reproductively inhibited animals and to determine if the treatment would promote recovery. 2. per capita food intake was significantly increased but per cent body fat tended to decrease and body weight did not significantly increase during t3 treatment. 3. mean testis and seminal vesicle weights of t ... | 1992 | 1354582 |
tissue-specific metabolism during normothermy and daily torpor in deer mice (peromyscus maniculatus). | previous work with deer mice (peromyscus maniculatus) has demonstrated that a significant acidosis occurs during daily torpor. in addition, carbohydrate levels are significantly lower, whereas fatty acid and ketone levels are significantly higher during torpor. the present study examined the effects of these in vivo acid-base and metabolite adjustments on in vitro 14c-glucose metabolism in tissues taken from normothermic and torpid deer mice. glucose oxidation in liver and vastus lateralis taken ... | 1992 | 1569409 |
photoperiod influences the critical caloric intake necessary to maintain reproduction among male deer mice (peromyscus maniculatus). | the concept of critical day length is well established among rodents; reproductive function is maintained when day lengths are greater than some specific threshold. in addition to day length cues, seasonal breeding in deer mice can also be regulated by food availability. the caloric threshold necessary to support reproduction remains unspecified for seasonally breeding rodents. the present study examined the interaction between photoperiod and food availability on reproductive function in adult ... | 1992 | 1536898 |
cotton rats and other small mammals as hosts for immature dermacentor variabilis (acari: ixodidae) in central oklahoma. | eight species of small mammals were evaluated as potential hosts for american dog ticks, dermacentor variabilis (say), in an upland, tallgrass prairie study site in central oklahoma. only hispid cotton rats, sigmodon hispidus, and deer mice, peromyscus maniculatus, were found to be important hosts for immature d. variabilis. although d. varibilis larvae and nymphs frequently infested both cotton rats and deer mice, cotton rats were the most important host species for both immature stages in the ... | 1992 | 1404263 |
seasonal prevalence of taenia taeniaeformis: relationship to age, sex, reproduction and abundance of an intermediate host (peromyscus maniculatus). | livers from 4,501 deer mice (peromyscus maniculatus) collected from a weedy habitat in northeastern california during 48 consecutive monthly samplings were examined microscopically for taenia taeniaeformis larva. although there were pronounced seasonal fluctuations in host density, there were no significant annual or season-related differences in cestode intensities in adult deer mice. there were no significant differences in prevalences associated with sex of the host, nor were there significan ... | 1992 | 1548801 |
uptake of environmental contaminants by small mammals in pickleweed habitats at san francisco bay, california. | small mammals were live-trapped in pickleweed (salicornia virginica) habitats near san francisco bay, california in order to measure the uptake of several contaminants and to evaluate the potential effects of these contaminants on the endangered salt marsh harvest mouse (reithrodontomys raviventris). tissues of house mice (mus musculus), deer mice (peromyscus maniculatus), and california voles (microtus californicus) from nine sites were analyzed for chemical contaminants including mercury, sele ... | 1992 | 1586203 |
factors associated with the mass of venom expended by prairie rattlesnakes (crotalus v. viridis) feeding on mice. | the purpose of this study was to assess through correlation analyses the various factors and consequences associated with the mass of venom injected by prairie rattlesnakes (crotalus v. viridis) into their natural prey, deer mice (peromyscus maniculatus). fifty-seven predator-prey interactions were studied via slow motion videotape review. the mass of venom expended by snakes during biting was quantified by enzyme-linked immunosorbent assay (elisa) of whole-animal homogenates. the quantity of ve ... | 1992 | 1626326 |
oxidoreduction of butanol in deermice (peromyscus maniculatus) lacking hepatic cytosolic alcohol dehydrogenase. | in view of conflicting information in the literature regarding enzyme systems responsible for alcohol oxidation in deermice previously reported to lack hepatic alcohol dehydrogenase (adh) activity, the reversibility of butanol oxidation was studied in vivo and in liver-perfusion systems. mixtures of [1,1-2h2]ethanol and butanol were given intraperitoneally to deermice lacking (adh-) or possessing (adh+) adh activity, followed by analysis of alcohols in blood by gc/ms. 2h exchange between the two ... | 1992 | 1740147 |
new host and locality records of coccidia (apicomplexa: eimeriidae) from rodents in the southwestern and western united states. | one hundred forty-seven murid and heteromyid rodents were collected from various sites in the southwestern and western united states (arizona, colorado, new mexico, texas, and utah) and baja california norte, mexico, and their feces were examined for coccidial parasites. of these, 53 (36%) were infected with at least 1 coccidian; 45 of 53 (85%) of the infected rodents harbored only 1 species of coccidian. infected rodents included: 10 of 22 (45%) neotoma albigula, 3 of 11 (27%) neotoma floridana ... | 1991 | 1779282 |
the effect of unsaturated and saturated dietary lipids on the pattern of daily torpor and the fatty acid composition of tissues and membranes of the deer mouse peromyscus maniculatus. | dietary lipids strongly influence the pattern of torpor and the body lipid composition of mammalian hibernators. the object of the present study was to investigate whether these diet-induced physiological and biochemical changes also occur in species that show shallow, daily torpor. deer mice, peromyscus maniculatus, were fed with rodent chow (control diet) or rodent chow with either 10% sunflower seed oil (unsaturated diet) or 10% sheep fat (saturated diet). animals on the unsaturated diet show ... | 1991 | 1783690 |
splenomegaly and reticulocytosis caused by babesia microti infections in natural populations of the montane vole, microtus montanus. | a survey for babesia microti in rodents was conducted at six sites within grand teton national park, wyoming. blood and spleen smears, hematocrits, and reticulocyte counts were made on all of the animals to evaluate parameters for the diagnosis of babesiosis. ticks were removed for identification. of 257 microtus montanus, 103 were infected with b. microti. in addition, five of 12 microtus pennsylvanicus and one of three arvicola richardsoni were parasitized by b. microti. peromyscus maniculatus ... | 1991 | 1818201 |
warble development by the rodent bot cuterebra fontinella (diptera: cuterebridae) in the deer mouse. | warbles induced by the rodent bot fly larvae, cuterebra fontinella, developed over a period of 3.5-4 weeks in the deer mouse peromyscus maniculatus. warble location, structure and dynamics were examined. clustering of warbles occurred primarily within the inguinal region of the deer mouse with a significant number favoring the area between the anus and genital organ. no differences in warble production were found in hosts of either sex. on two occasions, a warble was encountered forming directly ... | 1991 | 1882496 |
ontogeny of striking, prey-handling and envenomation behavior of prairie rattlesnakes (crotalus v. viridis). | the ontogeny of striking, prey-handling and envenomation behavior was studied in the prairie rattlesnake (crotalus v. viridis). snakes of three size classes (small, medium, large) were allowed to strike and envenomate deer mice (peromyscus maniculatus) of corresponding size. the mass of venom expended in a single strike, assayed by enzyme-linked immunosorbent assay (elisa) of whole-mouse homogenates, increased exponentially with length of the snake. small snakes embedded their fangs in prey for ... | 1991 | 1926185 |
morphological analysis of hair in the hr-2 mutant deer mouse (peromyscus maniculatus). | skin from 36 hairless deer mice (peromyscus maniculatus) homozygous for the recessive hr-2 mutation were analyzed for structural defects in hair and hair loss. comparison of mutant to wild-type hairs demonstrated characteristic abnormalities in cellular organization, hair shape, length, and fragility. matings between mutants homozygous for the hr-2 gene and for a second mutation producing hairlessness in deer mice, hr-1, showed that these two genes were nonallelic. structural abnormalities in ha ... | 1991 | 1940285 |
lyme disease in california: interrelationship of ixodid ticks (acari), rodents, and borrelia burgdorferi. | the association of immature ixodid ticks, several species of rodents, and the lyme disease spirochete, borrelia burgdorferi johnson, schmid, hyde, steigerwalt & brenner, was studied in two habitats in northern california in spring and summer 1985 and year-round in 1986. a total of 428 rodents were collected from ecotonal chaparral and a woodland-grass-rock outcrop; the former habitat yielded six species, the latter three species. the deer mouse, peromyscus maniculatus (wagner), and the piñon mou ... | 1991 | 1941942 |
survey for ixodes spp. and borrelia burgdorferi in southeastern wisconsin and northeastern illinois. | forested areas adjacent to milwaukee, wis., and chicago, ill., were investigated for rodents and ticks infected with borrelia burgdorferi, the causative agent of lyme disease. white-footed mice (peromyscus leucopus or peromyscus maniculatus), meadow voles (microtus pennsylvanicus), and eastern chipmunks (tamias striatus) were captured; and specimens from these animals were cultured for b. burgdorferi to define whether the midwestern lyme disease area currently encompasses these large metropolita ... | 1991 | 2007650 |
differential reproductive response to short photoperiod in deer mice: role of melatonin. | inhibitory photoperiod differentially effects reproduction in deer mice (peromyscus maniculatus nebrascensis). pituitary-testicular function is arrested in about one-third of short-day exposed males (reproductively responsive mice), while an equal number remain fertile (reproductively nonresponsive mice). both phenotypes are found in natural populations and their disparate reproductive responses have a genetic basis. to assess whether this difference is attributable to a prepineal/pineal or post ... | 1991 | 1779421 |
estimation of single generation migration distances from geographic variation in animal mitochondrial dna. | a new approach is introduced for the analysis of dispersal from the geographic distributions of mtdna lineages. the method is based on the expected spatial distributions of lineages arising under a multigeneration random walk process. unlike previous methods based on the predicted equilibria between genetic drift and gene flow, this approach is appropriate for non-equilibrium conditions, and yields an estimate of dispersal distance rather than dispersal rate. the theoretical basis for this metho ... | 1991 | 28567865 |
the comparative distribution of forebrain receptors for neurohypophyseal peptides in monogamous and polygamous mice. | several recent studies have suggested that the neurohypophyseal peptide oxytocin may have a role within the brain to mediate various forms of affiliative behavior. as the regulation of oxytocin function may be largely determined by the number and distribution of its membrane bound receptor, we investigated oxytocin receptor distribution in two peromyscus species selected for differences in affiliative behavior. using in vitro receptor autoradiography with the selective oxytocin receptor ligand [ ... | 1991 | 1656322 |
chemical and behavioral ecology of foraging in prairie rattlesnakes (crotalus viridis viridis). | free-ranging prairie rattlesnakes (crotalus viridis viridis) exhibit lengthy vernal migrations upon emergence from winter hibernation. a series of laboratory experiments was designed to test hypotheses regarding the function and causation of vernal movements. rattlesnakes obtained from wyoming and colorado populations were used. first, we hypothesized that the function of vernal movements is to locate small mammal prey. second, we predicted that activec. v. viridis use prey chemicals, as well as ... | 1990 | 24264898 |
different spatial scales of adaptation in the climbing behavior of peromyscus maniculatus: geographic variation, natural selection, and gene flow. | patterns of geographic variation in tree-climbing ability of peromyscus maniculatus were used to examine the influence of spatial variation in natural selection and gene flow on the genetic divergence of climbing behavior among populations. offspring of adults of two subspecies sampled from 10 localities in montane conifer forest, conifer woodland, and desert scrub/grassland habitats were raised in the laboratory and tested to determine their tree-climbing ability (the maximum diameter artificia ... | 1990 | 28569032 |
in vivo formation of a free radical metabolite of ethanol. | free radical metabolism of ethanol has been suggested as a factor in its hepatotoxicity. although evidence of lipid radical formation due to ethanol treatment in vivo has been reported, free radicals from ethanol itself have not been detected in living animals. however, by applying the epr spectroscopy technique of spin trapping to the study of ethanol-treated alcohol dehydrogenase-deficient deermice (peromyscus maniculatus), we have detected the alpha-(4-pyridyl-1-oxide)-n-t-butylnitrone (pobn) ... | 1990 | 2370854 |
tests of preferences of adult deer mice (peromyscus maniculatus bairdi) for siblings versus nonsiblings. | seven experiments were conducted to test the performance of adult deer mice (peromyscus maniculatus bairdi) in discriminating and preferring siblings versus nonsiblings. in two experiments there was no indication of preferences based on odor alone. further, there was no indication of kin discrimination in a seminatural enclosure. there was some indication that in a test apparatus, estrous females associate preferentially with male siblings rather than nonsiblings. the effect appears dependent on ... | 1990 | 2364663 |
tests of preferences of young deer mice (peromyscus maniculatus bairdi) for siblings versus nonsiblings. | three experiments were conducted to test the performance of young deer mice (peromyscus maniculatus bairdi) in associating preferentially with siblings versus nonsiblings. in experiment 1, neither males nor females preferred caged siblings versus nonsiblings. in experiment 2, with full contact permitted, nonsibling males were in contact as much as were sibling males. in experiment 3, with pairs of littermate pairs permitted full contact, there was no significant differential association. althoug ... | 1990 | 2364662 |
developmental changes in opiate-induced analgesia in deer mice: sex and population differences. | we examined developmental changes in nociception and mu (morphine) and kappa (u-50,488) opiate-induced analgesia in male and female deer mice of two different populations; peromyscus maniculatus artemisiae from a mainland region and p. m. angustus from a small island. both populations displayed significant developmental changes in nociception and morphine (10 mg/kg) and u-50,488 (10 mg/kg)-induced analgesia. basal thermal response latencies (nociceptive responses) and the levels of mu and kappa ... | 1990 | 2163727 |
sex differences in the inhibitory effects of the nmda antagonist, mk-801, on morphine and stress-induced analgesia. | we examined the effects of intraperitoneal administrations of the noncompetitive nmda receptor antagonist, (+) mk-801, its inactive enantiomer, (-) mk-801, and the prototypic opiate antagonist, naloxone, on restraint- and morphine-induced analgesia in male and female deer mice, peromyscus maniculatus. both restraint (30 min) and morphine (1.0 mg/kg) induced significant analgesic responses with male mice displaying significantly greater levels of opioid-induced analgesia than female animals. thes ... | 1990 | 2162721 |
intracellular ph during daily torpor in peromyscus maniculatus. | intracellular and extracellular acid-base parameters during normothermy and daily torpor were examined in deer mice (peromyscus maniculatus). [14c]dimethyloxazolidinedione and [3h]inulin were used to assess intracellular ph in liver, heart, skeletal muscle, and brain. buffering capacities were determined using tissue homogenates. a significant increase in plasma pco2 and cco2 during daily torpor indicates a respiratory acidosis. all tissues experienced a reduction in the calculated dissociation ... | 1990 | 2335594 |
hypothalamic monoamines and their metabolites in the deermouse, peromyscus maniculatus, during daily torpor. | deermice, subjected to food rationing, an ambient temperature below thermal neutrality and short photoperiod, were sacrificed in euthermia or during daily torpor. hypothalamic monoamine and metabolite levels were quantified by hplc with electrochemical detection. significant elevations in the levels (pg/microgram protein) of dopamine, 3,4-dihydroxyphenylacetic acid, and homovanillic acid were noted in the torpid animals. the concentrations of norepinephrine and serotonin displayed no significant ... | 1990 | 2297395 |
coat color genetics of peromyscus. i. ashiness, an age-dependent coat color mutation in the deer mouse. | ashy deer mice (peromyscus maniculatus) were first discovered about 1960 in a wild population from oregon. although indistinguishable from the wild type at weaning, ashy deer mice become progressively grayer with subsequent molts. the trait is inherited as an autosomal recessive and the symbol ahy is assigned for the locus. the trait is distinctly manifest by 6 months of age, at which time homozygotes have white hairs on the muzzle and at the base of the tail. the amount of white gradually incre ... | 1990 | 2177072 |
population differences in benzodiazepine sensitive male scent-induced analgesia in the deer mouse, peromyscus maniculatus. | we compared opioid and nonopioid involvement in the mediation of scent-induced analgesia in two populations of deer mice, peromyscus maniculatus; p. m. artemisiae from a mainland region and p. m. angustus from a small marine island. exposure to bedding taken from the soiled home cage of an isolated (dominant aggressive) male resident elicited a significant increase in the nociceptive responses of male deer mice from mixed sex pairs, with the island population of mice displaying significantly gre ... | 1989 | 2544899 |
muscle fiber size and chronic exposure to hypoxia. | sarcomere length is practically never considered when fiber size and dependent variables are compared between muscles or experimental conditions. because of the direct dependence of fiber cross-sectional area on muscle shortening, it is imperative to normalize measurements of fiber size, and related variables (e.g. capillary number/mm2 of fiber) to sarcomere length. we examined the relationship between fiber cross-sectional area and sarcomere length in muscles of animals chronically exposed to h ... | 1989 | 2782154 |
annual cyclicity of gall stone prevalence in deer mice (peromyscus maniculatus gambelii). | the prevalence of gall stones (100% cholesterol) in a deer mouse (peromyscus maniculatus) population located in siskiyou county, california (usa) was studied on a monthly basis from february 1985 through january 1988. during each year we documented a pronounced annual cyclicity with peak prevalence (31 to 53%) during the winter and low prevalence (2 to 3%) during late summer. gall stone prevalence was not related to sex or age of the animal. the earliest onset of gall stone production and the ma ... | 1989 | 2810546 |
serologic evidence of yersinia pestis infection in small mammals and bears from a temperate rainforest of north coastal california. | from 1983 to 1985, 463 serum samples from 11 species of mammals in redwood national park (rnp) (california, usa) were evaluated for antibodies to yersinia pestis by the passive hemagglutination method. yersinia pestis antibodies occurred in serum samples from 25 (36%) of 69 black bears (ursus americanus), one (50%) of two raccoons (procyon lotor), five (3%) of 170 dusky-footed woodrats (neotoma fuscipes), and one (less than 1%) of 118 deer mice (peromyscus maniculatus). two hundred seventy-three ... | 1989 | 2915403 |
dehydrogenase-dependent ethanol metabolism in deer mice (peromyscus maniculatus) lacking cytosolic alcohol dehydrogenase. reversibility and isotope effects in vivo and in subcellular fractions. | elimination of [2h]ethanol in vivo as studied by gas chromatography/mass spectrometry occurred at about half the rate in deer mice reported to lack alcohol dehydrogenase (adh-) compared with adh+ deer mice and exhibited kinetic isotope effects on vmax and km (d(v/k] of 2.2 +/- 0.1 and 3.2 +/- 0.8 in the two strains, respectively. to an equal extent in both strains, ethanol elimination was accompanied by an ethanol-acetaldehyde exchange with an intermolecular transfer of hydrogen atoms, indicatin ... | 1989 | 2925622 |
muscle capillary tortuosity in high altitude mice depends on sarcomere length. | at given capillary-to-fiber ratio and sarcomere length, capillary tortuosity determines capillary length and the geometry of blood-tissue exchange in muscles. it is therefore an important determinant of the potential efficiency of o2 supply to the muscle fibers. reports have indicated that capillary tortuosity increases with adaptation to hypoxia. unfortunately, sarcomere length was not taken into account. because capillary tortuosity increases substantially as the muscle shortens, it is importa ... | 1989 | 2749029 |
a reevaluation of chromosomal variation in populations of peromyscus maniculatus along an elevational gradient. | 1989 | 28568496 | |
element content in tissues of four rodent species sampled in the geysers geothermal steamfield. | liver and kidney tissue samples from four rodent species collected in the geysers geothermal steamfield of northern california were analyzed for content of 28 elements. element concentrations in samples from the developed region of the geysers were compared with samples from undeveloped reference regions to determine the influence of geothermal power development on element content in small mammal tissues. eight elements (b, ca, cu, mg, mn, p, sr, ti) were enriched in samples from the geysers, 12 ... | 1989 | 15092429 |
use of predator odors as repellents to reduce feeding damage by herbivores : iii. montane and meadow voles (microtus montanus andmicrotus pennsylvanicus). | this study investigated the influence of the major anal-gland compounds from the stoat (mustela erminea) and fecal and urine compounds from the red fox (vulpes vulpes) in generating an avoidance response by montane voles (microtus montanus), as well as suppressing feeding by montane and meadow (m. pennsylvanicus) voles on apple trees in orchards. in trap bioassays, a 1∶1 mixture of 2-propylthietane and 3-propyl-1,2-dithiolane significantly reduced vole captures. other mixtures of stoat compounds ... | 1988 | 24277015 |
hemoglobin polymorphisms in deer mice (peromyscus maniculatus): physiology of beta-globin variants and alpha-globin recombinants. | wild populations of deer mice (peromyscus maniculatus) contain hemoglobin polymorphisms at both alpha-globin (hba, hbc) and beta-globin (hbd) loci. population gene frequencies of beta-globin variants (d0 and d1 haplotypes) are not correlated with altitude, whereas a1 c1 alpha-globin haplotypes are fixed in low-altitude populations, and a0 c0 haplotypes reach near fixation at high altitudes. we examined the effects of alpha- and beta-globin variants on blood oxygen affinity and on aerobic perform ... | 1988 | 28563877 |
alpha-chain hemoglobin polymorphisms are correlated with altitude in the deer mouse, peromyscus maniculatus. | in deer mouse (peromyscus maniculatus) populations in the western united states, alpha-globin haplotype frequency, beta-globin haplotype frequency, and base-line blood oxygen affinity (measured after acclimation to low altitude) show strong correlations with native altitude. the correlations improve when an average regional altitude is substituted for the local altitude at collection sites. this substitution roughly compensates for the effects of gene exchange between populations in areas of hig ... | 1988 | 28563873 |
kinship, familiarity, aggression, and dominance in deer mice (peromyscus maniculatus) in seminatural enclosures. | this study was designed to test the effects of kinship and postweaning familiarity on male-male aggressive interactions in deer mice (peromyscus maniculatus) in a more naturalistic situation than that of most tests of kin discrimination. familiar males (i.e., those housed together from weaning) displayed significantly less aggression than unfamiliar males; kinship per se did not appear to affect levels of aggression. in addition, dominant males copulated more than subordinates and under some con ... | 1988 | 3165063 |
chromosomal pairing in deer mice heterozygous for the presence of heterochromatic short arms. | the pattern of chromosomal pairing was analyzed in male deer mice (peromyscus maniculatus and peromyscus sitkensis) heterozygous for the presence of heterochromatic short arms. g- and c-banding of somatic metaphases indicated that the presence of heterochromatic short arms increased the length of chromosome 4 by 15% in p. sitkensis and that of chromosome 8 by 9% in p. maniculatus. analysis of silver-stained late zygotene and early pachytene nuclei revealed a low frequency of unequal axial length ... | 1988 | 3371655 |
novelty-induced opioid analgesia in deer mice (peromyscus maniculatus): sex and population differences. | exposure to a new environment elicited significant, naloxone (1.0 mg/kg) reversible analgesic responses in three different populations of deer mice; peromyscus maniculatus artemisiae from the mainland, and p. m. angustus and p. m. triangularis from small marine islands. in all cases male deer mice displayed significantly greater levels of analgesia than females. in addition, the levels of analgesia were significantly greater in the insular than in the mainland populations. these results indicate ... | 1988 | 3345191 |
the relationship between food intake, body fat and reproductive inhibition in prairie deermice (peromyscus maniculatus bardii). | 1. reproductively-inhibited deermice selected from four laboratory populations consumed significantly less food than reproductively-proven pairs. 2. reproductively-inhibited animals predominantly, but not consistently, had reduced total body fat compared with reproductively capable deermice. 3. the per capita food consumption rate of two populations followed for 26 weeks since founding, decreased over time to about 65% of the daily intake of the proven animals used to found the populations. 4. a ... | 1988 | 2899486 |
cytochrome oxidase activity in brown fat varies with reproductive response and use of torpor in deer mice. | reproductive responses and thermogenic properties of brown adipose tissue (bat) were evaluated in individuals from an outbred population of deer mice (peromyscus maniculatus nebrascensis) after 10 weeks exposure to short photoperiod (8:16 light:dark) and cold ambient temperature (2 degrees c). deer mice populations are composed of phenotypes that differ in their reproductive response to environmental cues. these phenotypes also differ in body temperature regulation as indicated by their use of d ... | 1988 | 2845453 |
phylogeographic population structure of red-winged blackbirds assessed by mitochondrial dna. | a continent-wide survey of restriction-site variation in mitochondrial dna (mtdna) of the red-winged blackbird (agelaius phoeniceus) was conducted to assess the magnitude of phylogeographic population structure in an avian species. a total of 34 mtdna genotypes was observed among the 127 specimens assayed by 18 restriction endonucleases. nonetheless, population differentiation was minor, as indicated by (i) small genetic distances in terms of base substitutions per nucleotide site between mtdna ... | 1988 | 16593914 |
male scent-induced analgesia in the deer mouse, peromyscus maniculatus: involvement of benzodiazepine systems. | exposure to bedding taken from the soiled home cage of an isolated male resident elicited a significant increase in the nociceptive responses of male deer mice, peromyscus maniculatus artemisiae, from mixed sex pairs. the analgesia induced by exposure to the male scent was insensitive to the opiate antagonist, naloxone, and was blocked by either pre- or post-olfactory exposure injections of the benzodiazepine antagonist, ro 15-1788, or agonist, diazepam. this non-opioid analgesia was of brief du ... | 1988 | 2835786 |
vertical distribution of soil removed by four species of burrowing rodents in disturbed and undisturbed soils. | burrow volumes were determined in disturbed and undisturbed soils for four species of rodents in southeastern idaho. comparisons were made between soil types for the average volume and the proportion of the total volume of soil excavated from 10-cm increments for each species, and the relative number of burrows and proportion of total soil removed from beneath the minimum thickness of soil covers over buried low-level radioactive wastes. burrows of montane voles (microtus montanus) and deer mice ... | 1988 | 3280518 |
influence of photoperiod, ambient temperature and melatonin on testosterone synthesis and release during reproductive maturation in male deer mice. | four experiments were designed to investigate the influence of photoperiod and other environmental factors on androgen production and reproductive maturation in deer mice. male prairie deer mice (peromyscus maniculatus), born in a light/dark cycle of 6l:18d, either remained in this short photoperiod or were switched to a long day regimen of 16l:8d at weaning. in a cross-sectional experiment, the deer mice were killed between 3 and 8 weeks of age for measurement of serum testosterone concentratio ... | 1988 | 3346178 |
identification of p-450alc in microsomes from alcohol dehydrogenase-deficient deermice: contribution to ethanol elimination in vivo. | isozyme 3a of rabbit hepatic cytochrome p-450, also termed p-450alc, was previously isolated and characterized and was shown to be induced 3- to 5-fold by exposure to ethanol. in the present study, antibody against rabbit p-450alc was used to identify a homologous protein in alcohol dehydrogenase-negative (adh-) and -positive (adh+) deermice, peromyscus maniculatus. the antibody reacts with a single protein having an apparent molecular weight of 52,000 on immunoblots of hepatic microsomes from u ... | 1988 | 3395117 |
susceptibility of the gray wolf (canis lupus) to infection with the lyme disease agent, borrelia burgdorferi. | four juvenile gray wolves (canis lupus) were inoculated with live borrelia burgdorferi. one received an intravenous inoculum, a second was inoculated subcutaneously, and two more were fed peromyscus maniculatus sucklings which had earlier been inoculated with b. burgdorferi. the intravenously inoculated wolf developed a generalized lymphadenopathy and a persistent serum antibody titer to the spirochete which peaked at 1:512. borrelia burgdorferi was visualized in liver sections of this wolf usin ... | 1988 | 3411709 |
effect of smelter emissions on the hemogram of the deer mouse (peromyscus maniculatus). | blood samples were obtained from 284 deer mice (peromyscus maniculatus) live-trapped near two base metal smelters in northern manitoba, canada. hemoglobin and hematocrit values were significantly higher in mice trapped within 40-70 km of the smelters compared to those in control areas 185 to 190 km from the smelter. these increases appear to be normal physiological responses to a mild respiratory stress, as in a true secondary polycythemia of anoxic tupe. the mice are sensitive bioindicators of ... | 1988 | 15092500 |
the molecular organization of the beta-globin complex of the deer mouse, peromyscus maniculatus. | recombinant dna clones have been isolated that contain 80 kb of the beta-globin complex from the deer mouse, peromyscus maniculatus. comparisons of this complex with that from the laboratory mouse, mus domesticus (with an order 5'-hbby, hbb-bho, hbb-bhl, hbb-bh2, hbb-bh3, hbb-bl, hbb-b2 3') highlight organizational trends in the beta-globin complex since the two species diverged. unlike other mammals studied thus far, the deer mouse possesses three adult genes. partial sequence analysis indicate ... | 1987 | 3447002 |
accelerated wound repair in old deer mice (peromyscus maniculatus) and white-footed mice (peromyscus leucopus). | the closure of bilateral full thickness cutaneous wounds, made over the back with a sharp paper punch, was measured and assessed histologically in outbred deer mice (peromyscus maniculatus) and white-footed mice (peromyscus leucopus). in contrast to inbred c57bl/6j laboratory mice (mus musculus), in which the rate of wound repair was more rapid in young than in mature or aged mice (cohen et al., 1987), wound repair in peromyscus was most rapid in aged animals. aged peromyscus (45 to 70 months) a ... | 1987 | 3571866 |
platinum coat color locus in the deer mouse. | platinum coat color in the deer mouse, peromyscus maniculatus, is an autosomal recessive trait marking a locus, pt, distinct from silver (si), albino (c), blonde (bl), brown (b), and agouti (a). platinum deer mice are conspicuously pale, with light ears and tail stripe. the pewter trait is allelic with and phenotypically identical to platinum, and represents an independent recurrence of this mutant. the rate of recoveries of coat color mutations from wild deer mice is consistent with available d ... | 1987 | 3611714 |
neurons in the suprachiasmatic area are labelled after intravenous injections of horseradish peroxidase. | intravenous injections of horseradish peroxidase (hrp) produced labelled neurons in the suprachiasmatic area of house mice (mus musculus), deer mice (peromyscus maniculatus bairdi), and white-footed mice (peromyscus leucopus). in the two species of peromyscus, a significant proportion of the labelled cells was found within the suprachiasmatic nucleus (scn). these results suggest that when hrp is injected in the eyes to trace retinal inputs to the hypothalamus, some of the reaction product seen i ... | 1987 | 3622673 |
disruption of ejaculates by male copulation in deer mice (peromyscus maniculatus). | six experiments were conducted to analyze possible disruption of sperm transport occurring when one male deer mouse copulates soon after another male ejaculates. when a second male mated soon after the first, females had significantly fewer uterine sperm 1 hr later than when a delay of 7 or 15 min was imposed between males. however, it was impossible to detect any effect of such disruption on pregnancy initiation. similarly, artificial stimulation soon after an ejaculation was ineffective in dis ... | 1987 | 3685153 |
oral infection of peromyscus maniculatus with borrelia burgdorferi and subsequent transmission by ixodes dammini. | we determined if deer mice (peromyscus maniculatus) could be infected by borrelia burgdorferi and develop sufficient spirochetemia to infect larval ixodes dammini. ten p. maniculatus were infected orally with 0.05 ml phosphate buffered saline containing approximately 400 b. burgdorferi. on days 21 or 28 after infection (ai) larval i. dammini were fed on the deer mice. each of the p. maniculatus developed antibodies (up to 7 log2) to b. burgdorferi and b. burgdorferi was isolated from the blood o ... | 1987 | 3826500 |
serological survey of prospect hill virus infection in indigenous wild rodents in the usa. | we found serological evidence of infection with prospect hill virus, a hantaan-like virus isolated from meadow voles (microtus pennsylvanicus), in microtine and cricetid rodents trapped in maryland, west virginia, minnesota and california, usa. fluorescent antibodies were detected in sera from m. pennsylvanicus (74/277), m. californicus (39/185), clethrionomys gapperi (5/51), peromyscus maniculatus (4/22) and p. truei (1/11). sera from seropositive p. maniculatus contained neutralizing antibodie ... | 1987 | 2895510 |
experimental infection and horizontal transmission of modoc virus in deer mice (peromyscus maniculatus). | deer mice (peromyscus maniculatus) were inoculated with a sublethal dose of a field strain of modoc virus to determine patterns of viral persistence, shedding, and transmission. blood, serum, urine, fecal, and oral swab samples were collected at selected intervals until 63 days postinoculation (pi) after which lung, liver, spleen, kidney, and salivary glands were explanted. viral assays were conducted by intracranial inoculations of suckling mice and antibody titers were determined by the micro- ... | 1987 | 3035240 |
stress-induced opioid analgesia and activity in deer mice: sex and population differences. | we compared restraint stress-induced opioid, analgesic and locomotory responses of 4 different populations of male and female deer mice, peromyscus maniculatus artemisiae and p. m. nebrascensis from mainlands, and p. m. angustus and p. m. triangularis from small islands. all of the deer mice displayed immobilization-induced analgesia which was blocked by the prototypical mu-opiate antagonist, naloxone (1.0 mg/kg). in all of the populations males displayed significantly greater levels of analgesi ... | 1987 | 3427425 |
analysis of mitochondrial dna polymorphisms among channel island deer mice. | mitochondrial dna (mtdna) from 131 deer mice, peromyscus maniculatus, collected on the eight california channel islands and from seven southern california mainland locations, was isolated and analyzed for restriction endonuclease fragment polymorphisms. a total of 26 mtdna genotypes were distinguishable among the deer mice sampled. all of the island samples had mtdna restriction-fragment patterns not found among the mainland samples. distributions of specific restriction-fragment patterns provid ... | 1987 | 28564361 |
sex and day-night differences in opiate-induced responses of insular wild deer mice, peromyscus maniculatus triangularis. | we examined the effects of mu and kappa opiate agonists on the day- and night-time nociceptive, locomotory and ingestive behaviors of an island population of wild male and female deer mice, peromyscus maniculatus triangularis. the prototypical mu opiate agonist, morphine, had significant analgesic and locomotory effects, which were blocked by naloxone, and the specific delta opiate antagonist, ici 154,129, respectively. the specific kappa opiate agonist, u-50,488, had significant analgesic actio ... | 1987 | 3659070 |
chromosomal variation in peromyscus maniculatus populations along an elevational gradient. | 1987 | 28563794 | |
gonadal regression induced by caloric restriction is not mediated by the pineal gland in deer mice (peromyscus maniculatus). | the role of the pineal gland in mediating reproductive regression in response to nonphotoperiodic cues was assessed. a proportion of deer mice (peromyscus maniculatus) undergo gonadal regression subsequent to moderate food restriction. the reproductive regression after inanition qualitatively and quantitatively resembles short-day-induced regression. the physiological mechanisms responsible for gonadal regression after food restriction are unknown. the hypothesis that the mechanisms underlying p ... | 1987 | 3625465 |