Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| induction of tumors in the japanese house musk shrew, suncus murinus (insectivora), by dimethylbenz[a]anthracene. | the carcinogenic effect of 7,12-dimethylbenz[a]anthracene (dmba) was examined in the virgin female japanese house musk shrew, suncus murinus (family: soricidae, order: insectivora). leukemia, musk gland tumors, pilosebaceous tumors and sarcomas were induced in the dmba-treated shrews, whereas none of the controls developed any tumors up to 50 weeks of age. dmba emulsion was administered i.p. at a dose of 1.25 or 2.5 mg once a week, with either four or eight doses being given from 8 weeks of age. ... | 1991 | 1907223 |
| prenatal and postnatal development of the large intestine in the insectivore suncus murinus, the laboratory shrew. | development of the large intestine in the insectivore suncus murinus (the laboratory shrew) was investigated from day 21 to 30 of gestation and from birth to 20 days of age. two days before birth, the stratified epithelium in the large intestine changed into a single layer. although neither villi nor villus-like structures were ever present, fissures, corresponding to openings of the crypts, appeared on the mucosal surface before birth. these increased in number as well as in width and depth, co ... | 1991 | 1867402 |
| influences of gonadal and adrenal androgens on the side glands of suncus murinus. | in order to know the contribution of adrenal and gonadal androgens to the development of the side gland of suncus murinus, we studied the effects of gonadectomy and adrenalectomy on gland thickness and the plasma levels of testosterone, androstenedione (delta 4-dione) and dehydroepiandrosterone (dha). in males, castration decreased gland thickness to 71% of the control. the plasma levels of delta 4-dione and testosterone were also decreased from 4.16 +/- 0.50 and 0.65 +/- 0.10 ng/ml to 1.44 +/- ... | 1991 | 1794331 |
| retinofugal projections in the house musk shrew, suncus murinus. | retinofugal projections in the house musk shrew (suncus murinus) were studied with the wga-hrp method. after wga-hrp injection into the vitreous cavity of one eye, terminal labeling was seen in the suprachiasmatic nucleus, dorsal and ventral lateral geniculate nuclei, pretectum and superficial layer of the superior colliculus. the terminal labeling in the suprachiasmatic nucleus was more marked on the side ipsilateral to the injection than on the contralateral side, whereas that in other regions ... | 1991 | 1715530 |
| postnatal growth pattern of f1 hybrids of a cross between two strains of large and small musk shrews, suncus murinus. | in our previous comparison of the postnatal growth of two laboratory strains of the musk shrew (suncus murinus), the large shrews originating in bangladesh (ban strain) and the small shrews from nagasaki, japan (nag strain), we found that differences in the 120-day adult body weight of the two strains (ban: males 135.3g and females 82.0g; nag: 52.9 and 34.2g, respectively) reflect both an approximately 2.5 times longer linear growth phase and an approximately 1.5 times higher growth rate during ... | 1991 | 2044669 |
| an attempt at reciprocal crosses between laboratory strains of large and small musk shrews (suncus murinus)--influence of body-weight difference between sexes on mating success. | we conducted mating experiments between two laboratory strains of musk shrews (suncus murinus), the large-sized shrews (ban strain) originating from bangladesh and the small-sized animals (nag strain) from nagasaki, japan. in the 16 mating trials between 12 ban females (mean body weight of 87.9 g) and 11 nag males (52.3 g), highly aggressive fighting behaviors of the ban females toward the nag males were observed. the ban females stayed in nest boxes in cages, whereas the nag males kept out duri ... | 1991 | 2044661 |
| selective blockade of cytotoxic drug-induced emesis by 5-ht3 receptor antagonists in suncus murinus. | antiemetic effects of serotonin 5-ht3 receptor antagonists (ics205-930, zacopride, brl43694, gr38032f) were investigated in suncus murinus. veratrine, nicotine, copper sulfate, cisplatin, cyclophosphamide and motion sickness were used as emetic stimuli. serotonin 5-ht3 receptor antagonists did not inhibit emetic responses to veratrine, nicotine, copper sulfate and motion sickness. however, cisplatin- and cyclophosphamide-induced emesis was strongly blocked by them. both subcutaneous and intraven ... | 1991 | 2041220 |
| effects of food restriction and social cues on sexual maturation and growth in male musk shrews (suncus murinus). | in the first experiment, the effects of food availability on growth and reproduction were assessed by placing male musk shrews on 3 different feeding schedules, i.e. fed ad libitum, fed 50% of the amount eaten by the ad-libitum controls or fed 25% of the amount eaten by the ad-libitum controls. after 25 days, growth and sexual maturation were significantly retarded in both of the food-restricted groups compared to the control group. in the second experiment, the combined effects of food availabi ... | 1991 | 1995861 |
| age-associated and cell-type specific changes in ngf requirement for neurite regeneration from trigeminal ganglion cells of the shrew (suncus murinus). | low density (20-50 cells/cm2), dissociated cultures of trigeminal ganglion (trg) cells of the shrew, were made in a serum-free medium, and neurite growth was compared across ages of the animal and between ngf-free and ngf-rich conditions. trg cells from newborn shrew (0-3 days old), which grew long neurites in an ngf-rich medium, failed to grow any neurites in an ngf-free medium. in contrast, trg cells from aged shrew (16-19 months), which grew neurites without ngf, exhibited no further incremen ... | 1991 | 1986033 |
| scanning electron microscopy of the ovary in the house musk shrew, suncus murinus. | the structure of the house musk shrew (suncus murinus) ovary, prepared by the osmium-dmso-osmium method, was examined with a scanning electron microscope. many ovarian follicles in various stages of development can be seen in the musk shrew ovary, but fully matured follicles (graafian follicles) are never observed. in the inner layer of zona granulosa of the preantral follicles, the follicular cells containing a large amount of glycogen deposition in the cytoplasm are observed. folded and collap ... | 1991 | 1883074 |
| immunohistochemistry of the pituitary pars distalis of the musk shrew, suncus murinus. | immunocharacteristics of the pituitary pars distalis cell types of the musk shrew, suncus murinus, were studied by the unlabeled antibody enzyme technique, using peroxidase-antiperoxidase or avidin-biotin-peroxidase complex. the thyrotropin (tsh)-, gonadotropin (gth)-, corticotropin (acth)-, prolactin (prl)-, and growth hormone (gh)-secreting cells of the pd were identified on the basis of their immunoreactivity with different heterologous antisera. the tsh cells showed specific immunoreactivity ... | 1991 | 1663882 |
| response to opioids of isolated small intestine in the house musk shrew, suncus murinus. | 1. response to the opioids of isolated small intestine of suncus murinus, an insectivore, was examined and compared with that of guinea-pig ileum. 2. the mechanical response to morphine and u50,488h, preferential mu- and kappa-agonist respectively, was relaxation which was antagonized by tetrodotoxin and naloxone in the suncus small intestine. 3. methionine5-enkephalin and d-alanine2, d-leucine5-enkephalin, both preferential delta-agonists, elicited contraction or relaxation in the suncus small ... | 1991 | 1685436 |
| deficiency of apolipoprotein b synthesis in suncus murinus. | we reported previously that fatty liver is easily induced in a novel experimental animal, suncus murinus (suncus) by withholding food. in this study, we focused on lipoprotein and apolipoprotein secretion from the liver. the study of lipoproteins from this animal revealed that small amounts of lipoproteins with apolipoprotein (apo) e but without apo b were observed in the fraction of density less than 1.08 g/ml. in order to learn whether apo b is synthesized by the liver or not, isolated suncus ... | 1991 | 1783607 |
| comparative aspects of microsomal cytochrome p-450-dependent monooxygenase activities in musk shrew (suncus murinus), mongolian gerbil (meriones unguiculatus), harvest mouse (micromys minutus) and rat. | 1. the cytochrome p-450 content (0.75 +/- 0.13 nmol/mg microsomal protein) in musk shrew (suncus, suncus murinus) liver microsomes was lower than that (1.30 +/- 0.26) in rat liver microsomes, but it is approximately the same level as in the mongolian gerbil (meriones unguiculatus, 1.18 +/- 0.14), harvest mouse (micromys minutus, 1.11 +/- 0.02) and rat. 2. the hydroxylation activity (based on cytochrome p-450) of medium-chain fatty acids (otanoic, decanoic, lauric and tridecanoic acids) is much h ... | 1991 | 1799966 |
| serotonergic ligand binding in aging brain of experimental animals. | although the use of aging experimental animals for studying serotonergic neuronal changes is limited because of species differences, cholinergic neuronal deterioration does appear to be a feature common to mammalian aging brains. in the present study, a recently introduced experimental animal, suncus murinus (house musk shrew, an insectivore classified as being at the stem of the mammalian phylogenic tree) which in certain physiological characteristics is more closely related to the primate than ... | 1991 | 1833658 |
| induction of fatty liver by fasting in suncus. | we found that a fatty liver was easily induced in a novel experimental animal, suncus murinus (suncus), by withholding food. hepatic triglyceride content increased linearly for up to 24 h after fasting in these animals. serum levels of neutral lipids are very low in the fed state compared with those in rats, and decreased significantly after 24 h fasting. on the other hand, serum free fatty acids, which are at the same level in fed animals as in rats, increased threefold in the fasting suncus. i ... | 1991 | 1940621 |
| a comparative electron microscopic analysis of mechanoreceptors in the hard palate of the mouse (mus musculus; rodentia) and the musk shrew (suncus murinus; insectivora). | these mechanoreceptors were studied with particular regard to their type and the distribution. in both species they were concentrated in the crests of transverse palatine rugae. in the mouse, meissner corpuscles, glomerular corpuscles, and merkel cell nerve endings were seen in every palatine ruga, though the first antemolar ruga also contained simple and atypical lamellated corpuscles. in contrast, the palatine rugae of the musk shrew contained only simple corpuscles and merkel cell nerve endin ... | 1990 | 2076060 |
| localization of motoneurons innervating the stylohyoid muscle in the monkey, cat, rabbit, rat and shrew. | the distribution of motoneurons innervating the stylohyoid muscle was examined in the japanese monkey (macaca juscata), cat, rabbit, rat and house musk shrew (suncus murinus) using the retrograde tracing method of horseradish peroxidase. the enzyme was injected into the stylohyoid muscle after ligating the central cut ends of the main peripheral branches of the facial nerve supplying the superficial facial muscles, or the trunk of the glossopharyngeal nerve supplying the pharyngeal muscles. in t ... | 1990 | 2092061 |
| group a rotavirus infection in animals from an animal house and in wild-caught monkeys. | randomly selected samples from different animal colonies from two laboratory animal houses and from the wild-caught monkeys were tested for the presence of anti-rotavirus antibodies to estimate the rates of infection with group a rotavirus. antibodies to the common group a rotaviral antigen were detected by a competitive enzyme-linked immunosorbent assay (elisa) using reagents of who elisa rotavirus detection kit. the results of the study showed that white mice, albino rats, and guinea pigs from ... | 1990 | 2122998 |
| an immunohistochemical study on the distribution of endocrine cells in the gastrointestinal tract of the musk shrew, suncus murinus. | the endocrine cells in the gastrointestinal tract of the musk shrew were studied immunohistochemically. eleven kinds of endocrine cells, immunoreactive for serotonin, somatostatin, gastrin, cholecistokinin, gastric inhibitory polypeptide, motilin, secretin, neurotensin, pancreatic glucagon, enteroglucagon and bovine pancreatic polypeptide, were revealed. in the stomach, serotonin-, somatostatin-, gastrin-, pancreatic glucagon- and enteroglucagon-immunoreactive cells were detected. the first thre ... | 1990 | 2134360 |
| deficiency of beta-adrenoceptor-mediated relaxation in suncus trachea. | characteristics of beta-adrenoceptor in the tracheal smooth muscle of suncus murinus (suncus) were studied in comparison with those of rats and guinea pigs. isoproterenol induced concentration-dependent relaxation of suncus trachea. however, the maximal relaxation was very small, and about 1000 times higher concentration was necessary compared to the case of the guinea pig. the order of the sensitivity to isoproterenol and the maximal relaxation was guinea pig much greater than rat greater than ... | 1990 | 2155338 |
| antibodies raised against different oligopeptide segments of human dopamine-beta-hydroxylase. | we raised antibodies against 3 oligopeptide segments of human dopamine-beta-hydroxylase (hdbh) corresponding to the n-terminal (hdbh-n), the intermediate (hdbh-i), and the c-terminal (hdbh-c) amino acid sequences (residues 26-43, 452-468, and 582-598), respectively. we characterized the antibodies in terms of specificity by means of western blotting and immunohistochemistry. anti-hdbh-n antiserum recognized dbh in the brain (noradrenergic neurons in the pons and medulla oblongata) and adrenal me ... | 1990 | 2293101 |
| serum concentrations of thyroid hormones and activity of iodothyronine deiodinase in peripheral tissues of the house musk shrew, suncus murinus. | serum concentrations of thyroid hormones and the properties of iodothyronine deiodinase in tissues of the house musk shrew, suncus murinus, were examined and compared with those of the rat. serum concentrations of thyroxine (t4) and 3,3',5'-tri-iodothyronine (rt3) were higher, while the serum concentration of 3,5,3'-tri-iodothyronine (t3) was lower in the shrew than in the rat. among liver, kidney, skeletal muscle, heart, brown adipose tissue (bat), spleen, lung, testes and thymus homogenates of ... | 1990 | 2338528 |
| genetic relationship among the musk shrews, suncus murinus insectivora, inhabiting islands and the continent based on mitochondrial dna types. | cleavage patterns of mitochondrial dna (mtdna) by restriction endonucleases were examined in musk shrews collected at six trapping sites on two japanese and two indonesian islands, on sri lanka, situated close to the indian subcontinent, and on the mainland of east bengal in bangladesh. no variation of mtdnas was found among the japanese and indonesian shrews, despite their geographical isolation by the sera. in contrast, at least six mtdna types were present in the sri lanka and the bangladesh ... | 1990 | 2383245 |
| characterization of cell fusion in xc cells induced by suncus murinus mammary tumor virus. | syncytium formation in a rat tumor cell line (xc) induced by suncus murinus mammary tumor virus (sm-mtv) was studied. multinucleate giant cells containing 20-30 nuclei were formed in a monolayer of xc cells by cocultivation with x-ray-irradiated sm-mtv producing cells (sm-mt-1). by fluorescent antibody staining. sm-mtv antigens were demonstrated in the cytoplasm of syncytia, and budding particles and intracytoplasmic a particles were found in syncytial giant cells by electron microscopy. cell-fr ... | 1990 | 1701988 |
| immunohistochemical study of adenohypophysial gonadotropes in the musk shrew, suncus murinus l. (insectivora). | most gonadotropes in the pituitary of male suncus murinus l. are immunostained with both lh beta and fsh antisera, whereas only a few gonadotropes are positive only for lh beta. the former gonadotropes consist of polygonal or polyhedral cells of medium size, and can be identified by the presence of two types of secretory granules of low density: smaller ones (about 150-250 nm in diameter) which are spherical in shape, and larger ones of irregular form with a maximum diameter of about 1,500 nm. t ... | 1990 | 2128755 |
| existence of an endothelio-endothelial placenta in the insectivore, suncus murinus. | the interhemal membrane of the chorioallantoic placenta in the insectivore suncus murinus was investigated by means of electron microscopy. in the interhemal membrane the syncytiotrophoblast clearly intervened between the hypertrophied maternal endothelium and the fetal endothelium by day 20 of pregnancy. although the syncytiotrophoblast showed a sieve-like feature from day 20 to 24, it was distinctly continuous. the syncytiotrophoblast, however, became discontinous in most areas of the labyrint ... | 1990 | 2257611 |
| composition of myofiber types in limb muscles of the house shrew (suncus murinus): lack of type i myofibers. | postural muscles have many type i myofibers, which reacted strongly for acid-stable myosin atpase and were unreactive for alkali-stable myosin atpase (ariano et al., j. histochem. cytochem., 21:51-55, 1973; armstrong et al., am. j. anat., 163:87-98, 1982; smith et al., j. neurophysiol., 40:503-513, 1977). house shrews (suncus murinus) keep abducting their limbs in locomotion and hardly lift their trunk off the ground. the limb muscles of suncus were examined by histochemical methods to determine ... | 1990 | 2146905 |
| the intermediate epithelium lining the nasopharynx of the suncus murinus. | in the adult suncus murinus, the rostral part of the nasopharynx is lined with the ciliated columnar epithelium continuing from the nasal cavity, while the laryngopharynx with the stratified squamous epithelium; i.e., the epithelium lining the caudal part of the nasopharynx forms the transitional zone between the ciliated columnar epithelium and the stratified squamous one. the epithelium shows gradations ranging from ciliated stratified low-columnar through stratified cuboidal to stratified squ ... | 1990 | 2216310 |
| effects of photoperiod and social variables on reproduction and growth in the male musk shrew (suncus murinus). | in exp. 1, the time course for the photoperiodic response in juvenile male musk shrews was examined by exposing animals to short (10l:14d) or long (14l:10d or 18l:6d) daylengths for 10, 20, 40 or 56 days. when compared with the response of animals maintained in long days, those exposed to short days showed an inhibition of reproductive maturation by 40 days of treatment. in exp. 2, the combined effects of photoperiod and social cues were investigated in juvenile males that were either housed in ... | 1990 | 2401995 |
| social cues influence growth and sexual maturation of the male musk shrew (suncus murinus). | musk shrews were maintained from weaning (20 days of age) for 20 or 40 days in one of several social conditions. in exp. 1, young males housed with adult females gained more weight and had heavier sex accessory organs than did young males housed with an adult male or reared alone. in exp. 2 this same pattern of accelerated growth and sexual maturation was found when males were reared directly with an adult female or in a split cage where a wire barrier served to separate the male and his adult f ... | 1990 | 2401994 |
| prolonged copulatory behavior facilitates pregnancy success in the musk shrew. | female musk shrews (suncus murinus) are sexually receptive and actively seek contact with males during the first ten days of pregnancy. in the series of experiments reported here we examined the effects of prolonged copulatory behavior on pregnancy success. females received multiple ejaculations either on the same day or over the course of up to six days. when ejaculations were distributed over an interval of several days, the number of females delivering litters was significantly increased. the ... | 1990 | 2388938 |
| the ultrastructure of the ganglionated nerve plexus in the nasal vestibular mucosa of the musk shrew (suncus murinus, insectivora). | a ganglionated nerve plexus (gnp) found in the nasal vestibular mucosa of the adult musk shrew, and most likely belonging to the nervus terminalis, was studied by electron microscopy. the gnp, which contained ganglion cells and both myelinated and unmyelinated nerve fibers, was located in the subepithelial layer of the mesial vestibular mucosa of the snout processes. the ganglion cells were characterized by an eccentrically located round nucleus, dispersed mitochondria and golgi apparatuses, and ... | 1990 | 2372438 |
| role of androgens in the regulation of sexual behavior in the female musk shrew. | these experiments were conducted to determine whether androgens are involved in the regulation of female sexual behavior in the musk shrew (suncus murinus). in the musk shrew, sexual behavior can be reinstated after ovariectomy by the administration of supraphysiological doses of either estradiol (e2) or testosterone. however, physiological doses of e2 are not effective in this regard. to examine the role of androgens, ovariectomized (ovx) females received testosterone-filled hormone implants. t ... | 1990 | 2111894 |
| retinal cysts in the eye of the asian musk shrew, suncus murinus, (mammalia, insectivora). | the development of retinal cysts in the eye primordia of suncus murinus embryos was studied. retinal infoldings were first identified in the 17.5-day-old embryo (crown rump length--crl = 6.3 mm). at this time, the apex of the developing retinal fold could be identified attached to the lens. the pigmented epithelium did not take part in the formation of the cyst. the retinal fold closed, to form a cyst, by day 23 of embryonic development (crl = 14.0 mm). the newly formed retinal cyst remained con ... | 1990 | 2324346 |
| environmental regulation of reproduction in an opportunistic breeder: the musk shrew (insectivora: suncus murinus). | in summary, photoperiod, social cues and food availability impact upon the reproductive system of the male musk shrew to alter the timing of reproductive maturation and hence opportunistic breeding. we can speculate that there might be a hierarchy to these environmental inputs. we suggest that for shrews living on guam, food availability is the primary cue, whereas social and photoperiodic signals play modulatory roles. the relative importance of these three external cues most likely depends upo ... | 1990 | 2381955 |
| comparison of various motion stimuli on motion sickness and acquisition of adaptation in suncus murinus. | effects of various types of motion stimuli were compared to investigate optimum method to elicit motion sickness and adaptation in suncus murinus (suncus). three different direction of shaking in the horizontal plane, back and forth, right and left and revolving, induced emetic response to the similar extent. however, vertical shaking was far less effective in inducing motion sickness. mild and severe horizontal shaking (15 min per day) was continued for 14 days and emetic response to standard m ... | 1990 | 2303099 |
| adenomatous hyperplasia and adenomas in the lung induced by chronic feeding of butylated hydroxyanisole of japanese house musk shrew (suncus murinus). | a carcinogenicity study on butylated hydroxyanisole (bha) was carried out in japanese house musk shrews (suncus murinus) (suncus), which have no forestomach. bha was mixed with the basal diet and was processed into pellets. one hundred and twenty-two female and 130 male suncus were maintained with a diet containing 0, 0.5, 1.0 or 2.0% bha for 80 weeks. all of the suncus of the 2.0% bha groups died of bleeding in the gastrointestinal tract within 8 weeks after the commencement of the treatment. t ... | 1990 | 2295121 |
| the epithelium lining the orifice of the laryngeal gland of the suncus murinus, with special reference to the "intermediate epithelium (nakano)". | in the lateral wall of the laryngeal ventricle of the suncus murinus, only a few excretory ducts of the laryngeal gland opened that drained the extensive lobular system. the ducts opened into the "intermediate epithelium (nakano, t.: acta anat. 127: 22-47, 1986)," which lined the transitional zone between the ciliated columnar epithelium and the stratified squamous one, and that showed gradations ranging from the ciliated stratified low-columnar through stratified cuboidal to stratified squamous ... | 1990 | 2278528 |
| characteristic features in the "laryngotrachea" of suncus murinus. | in the larynx of the suncus murinus (house musk shrew), the cricoid cartilage was situated laterally to and overlapped with the 1st, the 2nd, and a part of the 3rd tracheal cartilages. the term "laryngotrachea" was used for the region maintained by both the cricoid cartilage and the tracheal ones. it is suggested that the condition of the cartilages in suncus laryngotrachea is the most primitive condition in mammals. in the dorsal wall, just caudal to the plate of the cricoid cartilage and dorsa ... | 1990 | 2099301 |
| the musk shrew, suncus murinus, a unique animal model for the study of female behavioral endocrinology. | insectivora is the third largest mammalian order, composed of a number of unusual species considered to be the most primitive of the modern eutherian mammals. yet, little is known about the members of this evolutionarily unique and important group. the musk shrew (suncus murinus) is a convenient and practical laboratory animal. the study of the reproductive biology of this species will yield needed comparative data. moreover, the little information that we have collected on this species suggests ... | 1990 | 1974796 |
| identification of lactotropes (prl cells), somatotropes (gh cells), corticotropes (acth cells) and thyrotropes (tsh cells) in the pituitary gland of the musk shrew, suncus murinus l. (insectivora), by immunohistochemistry. | by means of immunohistochemistry, lactotropes, somatotropes, corticotropes and thyrotropes in the pituitary of the male musk shrew, suncus murinus l., were identified at the electron-microscopic level. lactotropes were classified into three types: type i containing large (200-450 nm in diameter) round secretory granules, type ii with medium-sized (150-250 nm in diameter) ones and type iii with small (50-150 nm in diameter) ones. somatotropes were also classified into type i somatotropes that con ... | 1990 | 1963727 |
| the foci of the red bone marrow observed in the laryngeal cartilages of the suncus murinus. | in the suncus murinus, the thyroid, the cricoid and the arytenoid cartilages were in part ossified. the foci of the red bone marrow, termed as the "marrow foci", were observed in the ossified portion of the cartilages. the marrow foci were filled with mature and immature blood cells. it is suggested that the marrow foci take part in active hematopoiesis in the suncus. further, a canal which connected the marrow cavity and the outside of the cartilage was occasionally seen. it seems that the cana ... | 1989 | 2608261 |
| ultrastructural features of the developing eosinophils in bone marrow and spleen of the musk shrew, suncus murinus. | eosinophilopoiesis in the musk shrew, suncus murinus, a representative of the order insectivora, was studied by light and electron microscopy. to examine biochemical features of cytoplasmic granules, extraction with proteolytic enzymes was carried out on ultrathin sections of bone marrow. in this species, eosinophils are produced in the same manner in both spleen and bone marrow. developing eosinophils were distinguished as belonging to four stages, recognized by ultrastructural changes in cytop ... | 1989 | 2600974 |
| determination of catecholamines and their metabolites in adrenals of stress-loaded and wild suncus (suncus murinus). | the contents of catecholamines and their metabolites were measured in the adrenals of 3 groups of suncus. the first group was naive housed suncus; the second, suncus with stress-loading; and the third, wild ones. there were no significant differences in dopamine, norepinephrine and normetanephrine levels among the control, stress and wild groups. the content of epinephrine, however, decreased in the stress and wild group to 57% and 18%, respectively. these results suggest that housed suncus can ... | 1989 | 2622098 |
| the distribution of endocrine cells in the mucosa of the gastrointestinal tract of the house musk shrew, suncus murinus (insectivora). | the distribution of endocrine cells in the gastrointestinal tract of the house musk shrew, suncus murinus (family soricidae, order insectivora) was studied immunohistochemically. the hormones investigated were gastrin, cholecystokinin (cck), somatostatin, secretin, glucagon, gastric inhibitory polypeptide (gip), motilin and neurotensin. in the gastric mucosa, gastrin and somatostatin cells were only found in the pyloric regions, and no other hormonal cell-types were observed. in the intestinal m ... | 1989 | 2582480 |
| male-related chemical cues promote sexual receptivity in the female musk shrew. | the role of conspecific chemical cues in the activation of sexual behavior was investigated in the female musk shrew (suncus murinus). in experiment 1, virgin female musk shrews were exposed to either clean cages or cages recently vacated by an adult male. regardless of whether the male used for the sexual behavior test was "familiar" to the female (having spent the 24 h exposure in his vacant cage) or "unfamiliar," females exposed to male-related cues received mounts from males significantly so ... | 1989 | 2705979 |
| annual profiles of sex steroids in blood plasma and ovarian tissue of wild female musk shrew, suncus murinus. | relative ovarian weights with bursa and annual profiles of sex steroids have been described in the female musk shrew, suncus murinus, collected in the vicinity of rawalpindi, pakistan. the relative gonadal weight was basal (23.20 +/- 1.20 mg/100 g) during anoestrus but enhanced (39.93 +/- 2.73 mg/100 g) abruptly at the onset of the breeding season. plasma progesterone concentrations, measured during different parts of the year, indicated elevated levels during the late pregnant stage (p less tha ... | 1989 | 2615037 |
| histochemistry of glycoconjugates in ovarian follicles of the adult house musk shrew, suncus murinus. | in ovarian follicles of the adult house musk shrew, suncus murinus, glycoconjugates have been studied by means of light- and electron-microscopic histochemistry. the results obtained are that: (1) glycoconjugates of the zona pellucida of oocytes are provided with vicinal diol and acidic groupings, and sialic acid-galactose dimer, alpha-d-mannose, alpha-d-glucose, beta-d-galactose, n-acetyl-d-glucosamine and alpha-l-fucose residues; (2) glycoconjugates of the intercellular matrix of the granulosa ... | 1989 | 2609922 |
| nucleotide sequence of suncus murinus immunoglobulin mu gene and comparison with mouse and human mu genes. | both primates and rodents apparently originated from insectivores and then evolved separately. we isolated the immunoglobulin mu gene from dna of the insectivore suncus murinus and determined its nucleotide sequence. the gene organization was ch1 exon (318 bp)-intron (89 bp)-ch2 exon (345 bp)-intron (80 bp)-ch3 exon (318 bp)-intron (85 bp)-ch4 exon (392 bp)-coding sequence and 3'-untranslated region. comparison of nucleotide sequences of mu genes between mouse, human and suncus murinus indicated ... | 1989 | 2497033 |
| characterization of three forms of cytochrome p-450 inducible by 3-methylcholanthrene in golden hamster livers with special reference to aflatoxin b1 activation. | three forms of cytochrome p-450 of liver microsomes of 3-methylcholanthrene-treated golden hamsters were purified and characterized as regards their catalytic activity toward aflatoxin b1-related hepatocarcinogenic mycotoxins. these include two major forms, designated as cytochrome p-450-afb (p-450-i) and p-450-ii, and one minor form, p-450-iii. cytochromes p-450-afb, p-450-ii, and p-450-iii have their absorption maximum in the carbon monoxide-complex of the reduced form at 448.5, 447.0, and 448 ... | 1989 | 2509440 |
| [three dimensional structure of the connective tissue papillae of the tongue in suncus murinus]. | the surface structure of the connective tissue papillae (cp) of suncus murinus tongue was observed by sem after fixing with karnovsky's fixative and removal of the epithelial cell layer with 3n or 8n hcl. on the surface of the slender conical tongue, there are densely distributed filiform papillae among which fungiform papillae are seen sporadically. a pair of vallate papillae are situated in the posterior region of the tongue. filiform papillae appear somewhat different externally depending on ... | 1989 | 2519278 |
| scanning, transmission and immunoelectron microscopical studies of the tonsil-like lymphoid organ of normal and horseradish-peroxidase-injected laboratory suncuses. | fine structures of normal and horseradish peroxidase (hrp)-stimulated tonsil-like lymphoid organs of the laboratory suncus (suncus murinus) were examined by scanning, transmission and immunoelectron microscopies. the normal organs appear as a pair of small oval protrusions at the upper lateral sites of the fauces, and consist of a single lymph nodule with a germinal center and a crypt-like epithelium with prominent lymphoid cell infiltration. postcapillary venules (pcv) and efferent lymphatics a ... | 1989 | 2603630 |
| the intermediate epithelium lining the larynx of the suncus murinus. | in the larynx of the suncus murinus the stratified squamous epithelium lines the tip of the caudal surface of the epiglottis and the region close to the vocal process of the arytenoid cartilage, while the ciliated columnar epithelium is located in the laryngeal sac and the dorsal part of the vocal fold. further, in the transitional zone between the stratified squamous epithelium and the ciliated columnar one there exists the epithelium which shows gradations ranging from stratified squamous thro ... | 1989 | 2608258 |
| chigger mite infestation of small mammals in a feral biotope of a public park area of south delhi. | examination of bandicota bengalensis (8) and suncus murinus (4) trapped in a feral biotope of a public park area of south delhi revealed presence of the known scrub typhus vector leptotrombidium (l.) deliense, the suspected vector gahrliepia (s.) ligula and gahrliepia (walchia) sp. of chigger mites, on them. the epidemiologically important population indices (chigger infestation rate-cir and incidence rate--1r) were estimated. the overall cir of the three mite species on the hosts was 2.83 mite/ ... | 1989 | 2638383 |
| major ocular glands (harderian gland and lacrimal gland) of the musk shrew (suncus murinus) with a review on the comparative anatomy and histology of the mammalian lacrimal glands. | the harderian gland of the musk shrew suncus murinus is elongated anteroposteriorly from in front of the eye to behind the ear. the gland is divided into two portions: an anterior portion (a portion) and a posterior portion (p portion). the single secretory duct of the gland emerges from the anterior end of the p portion, receives several secretory ducts of the a portion during the course along it, runs around the ventral aspect of the eyeball, and finally opens into the anterior corner of conju ... | 1989 | 2664187 |
| isolation and characterization of shrew (suncus murinus) liver alcohol dehydrogenases. | 1. starch gel electrophoresis of adult shrew (suncus murinus) liver extracts revealed five forms of alcohol dehydrogenase (adh 1-5) and four of them were purified. 2. adh-4 and adh-5 resemble human class i adh in terms of electrophoretic mobility, substrate specificity and sensitivity to pyrazole inhibition. 3. adh-2 does not belong to any of the three classes of human adhs but rather with catalytic properties similar to those of the class b adh found in guinea pig liver. 4. adh-1 prefers second ... | 1989 | 2666017 |
| ultrastructure of secretory ameloblasts in the house musk shrew, suncus murinus, insectivora. | tooth germs from neonatal house musk shrews, suncus murinus, were used for the study. the tooth morphogenesis was compared electron microscopically to that of primates. in the tooth germ at the bell stage, the ameloblast was 3 x 50 microns in size, columnar in shape and had several tubular-type golgi apparatus which were at the distal end of the cell. most mitochondria were noted at the proximal end of ameloblasts. tomes' processes were 1 micron in width, protruded 10 microns from the ameloblast ... | 1989 | 2718719 |
| suncus murinus. observations on ecology, distribution, status to plague in bombay. | the common house shrew suncus murinus has been shown to play an important role in maintenance and perpetuation of plague infection by earlier plague workers. with the control of human plague there is no knowledge about foci of plague in small mammals associated with man. present study was carried out to fill in this lacuna. studies carried out in the present paper reveal that s. murinus does not harbour any plague infection in bombay. this species is widely distributed in bombay and is found to ... | 1989 | 2723422 |
| comparative studies on the stereo architecture of the connective tissue papillae in some mammalian tongues. | the epithelial cell layer was removed from the underlying connective tissue papillae by the method of long term hydrochloric acid treatment and the connective tissue surface was observed by scanning electron microscopy. tongues of insectivora (suncus murinus), rodentia (mouse, rat, guinea pig), carnivores (dog, cat) and primates (man) were studied. each animal species had proper architecture of connective tissue papillae as to four types of lingual papillae. there was a tendency for the stereo s ... | 1989 | 2748642 |
| organ distribution, purification and characterization of kynureninase in suncus murinus (insectivora) and anthranilic acid level in the serum. | 1. the highest kynureninase activity was measured in suncus liver compared with other organs tested. the holo-enzyme activity detected in liver was 25%. 2. the enzyme mainly localized in liver cytosol was purified to a single protein band by heat treatment, ammonium sulfate fractionation, deae-sepharose, hydroxyapatite and phenyl-sepharose column chromatography. 3. the purified enzyme was effective for both kynurenine and 3-hydroxykynurenine, and showed the optimum ph at 8.5 against both substra ... | 1989 | 2752727 |
| effect of castration on epididymal sperm storage in male musk shrews (suncus murinus) and mice (mus musculus). | reproductively mature male musk shrews and mice were bilaterally castrated. epididymal sperm numbers and motility were assessed 0, 2, 4 and 6 weeks after surgery. seminal vesicle weights and plasma concentrations of total androgens were also measured. in male musk shrews, 30% of the original epididymal sperm numbers were still present 2 weeks after castration and motile spermatozoa were present in 2 of 7 individuals. by 4 and 6 weeks after castration the numbers of spermatozoa remaining declined ... | 1989 | 2754641 |
| side gland of suncus murinus as a new model of sebaceous gland: 5 alpha-reductase, androgen receptor, and nuclear androgen content in male and female animals. | the side gland of suncus murinus is composed of well-developed sebaceous glands in both males and females. we measured the 5 alpha-reductase activity, androgen receptor content, and the intranuclear concentrations of testosterone and dihydrotestosterone in this side gland taking it as a new experimental model of human sebaceous glands. lineweaver-burk plot analysis suggested the presence of two classes of 5 alpha-reductase with different km for testosterone in the homogenate. the enzyme activity ... | 1989 | 2919895 |
| effects of estradiol valerate on the uterus of the musk shrew (suncus murinus l.). | the effects of exogenous estradiol valerate on some uterine characteristics of the musk shrew were investigated. treatment with the steroid for either 1 day or 7 days did not noticeably alter luminal epithelial cell height, endometrial gland epithelial cell height or diameter, or number of endometrial glands. the reciprocal values of cell density of circular muscle and deep endometrial layers and endometrium-to-myometrium ratio of the uterus increased significantly in response to 7 days of stero ... | 1989 | 1385261 |
| preparation and characterization of monoclonal antibodies against a form of hamster liver cytochrome p-450 highly specific to aflatoxin b1. | monoclonal antibodies were prepared against a form of cytochrome p-450 (designated as cytochrome p-450-i) purified from 3-methylcholanthrene-treated hamster livers which is highly specific to aflatoxin b1. the cytochrome p-450-i was detected in elisa and western blots in liver microsomes from 3-methylcholanthrene-treated hamsters and also from non-treated and phenobarbital-treated hamsters in smaller amounts. however, none of the liver microsomes from 3-methylcholanthrene-treated rat, rabbit, gu ... | 1988 | 3132167 |
| observations on commensal rats and their status to plague in bombay. | the distribution pattern of various types of commensal rodents in bombay city reveals that bandicota bengalensis constitutes the predominant commensal rodent species followed by r. rattus and rattus norvegicus. apart from these three types, bandicota indica, m. musculus and an insectivore (suncus murinus) are the three species of commensal small mammals that are frequently encountered in or near human habitations. these small mammals are prevalent throughout the year and their percentage distrib ... | 1988 | 3221091 |
| unique features of secretory granules observed in the pituitary growth hormone-secreting (gh) cells of the musk shrew (suncus murinus l). | unique rod-shaped secretory granules were observed among oval or spherical secretory granules in gh cells of the anterior pituitary gland of musk shrew using the protein a-gold procedure combined with electron microscopy. the rod-shaped and spherical secretory granules were both immunoreactive by the immuno-gold method using antiserum to sheep gh. the rod-shaped secretory granules, which seem to be formed directly from the golgi vesicles, extend from several hundred to several thousand nm in len ... | 1988 | 3342430 |
| isolation of mycoplasmas from house musk shrews (suncus murinus). | mycoplasmas were isolated from various sites of experimental and wild house musk shrews (suncus murinus). the oral cavity was the most prominent site to harbor mycoplasmas (15/18; 83%), followed by the nasal cavity (9/18; 50%). all of the isolated strains required serum for their growth and all fermented glucose. they were found to be serologically homogeneous by growth inhibition test but did not cross-react with several type strains of mycoplasma or reference strains of murine, feline, canine, ... | 1988 | 3416940 |
| major structural polypeptides of retrovirus produced by a suncus murinus mammary tumor cell line and type d retrovirus share interspecies antigenic determinants. | constitutive polypeptides of retrovirus produced by a suncus murinus mammary tumor cell line (sm-mtv) were characterized by immunofluorescence and immunoblotting. the major structural polypeptide of sm-mtv, molecular weight 44/43k, immunologically cross reacted with the structural polypeptides of mason-pfizer monkey virus (mpmv) (molecular weights 27k and 12/10k). sm-mtv constitutive polypeptides did not show antigenic relatedness with those of the following mammalian retroviruses: murine mammar ... | 1988 | 2460996 |
| characterization of mixed-function oxidases and purified cytochrome p-450 of livers of house musk shrew, suncus murinus. | characteristics of mixed-function oxidases in the liver of house musk shrew, suncus murinus, were studied. the basal level of cytochrome p-450 and the activity of drug-metabolizing enzyme in hepatic microsomes of suncus murinus is relatively lower than that of rats, while the level of cytochrome b5 and nadph-cytochrome c reductase is approximately the same as that of rats. the treatment of suncus murinus with phenobarbital and 3-methylcholanthrene elevated the level of cytochrome p-450 and the a ... | 1988 | 2894946 |
| structural and functional analysis of long terminal repeats of suncus murinus mammary tumor virus. | a 2.7-kilobase (kb) cdna sequence complementary to suncus murinus mammary tumor virus (sm-mtv) genomic rna [corrected] was prepared using purified virions produced by the sm-mt cell line, which had been established from a spontaneous mammary tumor of s. murinus. it was found, by using this cdna in southern hybridization experiments, that sm-mtv was endogenous to this animal and that some 50 copies of endogenous provirus were present per haploid cellular genome. in addition, a proviral sm-mtv dna ... | 1988 | 2831384 |
| characteristics of cardiac beta-adrenoceptors in suncus murinus. | 1988 | 2854498 | |
| histological observations on the pharynx of the musk shrew, suncus murinus. | 1988 | 3250171 | |
| prenatal and postnatal development of the small intestine in the insectivore suncus murinus. | the development of the small intestine in the insectivore suncus murinus was noted during the period from 21 days' gestation to 20 days after birth. at 21 days of gestation, the proximal small intestine exhibited the beginning of villus formation, whereas the distal small intestine preserved the stratified epithelium. stratified epithelium in the distal small intestine changed into a single layer by 24 days' gestation. at 26 days' gestation, each epithelial cell was immature; but by 28 days matu ... | 1988 | 3189198 |
| estrogen binding component in the pilosebaceous tumor developed in suncus murinus. | we transplanted a pilosebaceous tumor developed on the sidegland of suncus murinus to male nude athymic (balb/c-nu/nu) mice. this tumor can be transplanted to female hosts as well, with a lower rate of graft-taking and slower growth rate. in this study we demonstrated the presence of macromolecules which specifically bind to estrogen. measurement of 17 beta-estradiol (e2) binding by a dextran-coated charcoal assay revealed that the number of binding sites and the dissociation constant were 22.3 ... | 1988 | 3215143 |
| patterns of sexual receptivity in the female musk shrew (suncus murinus). | female musk shrews (suncus murinus) were tested daily to examine patterns of sexual receptivity. when only mounting was used as a criterion (to avoid pregnancy), nonpregnant females remained sexually receptive to males every day for 14 consecutive days. when insemination was allowed, most females continued to copulate for the first 5 days of pregnancy. receptivity declined markedly around day 10 of gestation, but a few females were receptive even into late pregnancy. lactating females copulated ... | 1988 | 3397051 |
| ultrastructural and immunocytochemical studies of prolactin-secreting cells (prl cells) in the anterior pituitary gland of the female musk shrew (suncus murinus l.). | prolactin-secreting cells (prl cells) in the anterior pituitary gland of the female musk shrew were identified by the protein a-gold procedure combined with electron microscopy. their secretory granules were spherical, and showed various sizes ranging in diameter from 100 nm to 800 nm according to the difference in physiological conditions of the animals. in pregnant and lactating animals, the prl cells exhibited morphologically active features, i.e., a large prominent golgi apparatus and a well ... | 1988 | 3382031 |
| alleles at plasma alpha-amylase locus(amy-1) of the house musk shrew(suncus murinus): frequency distribution and new variants in laboratory lines and local asian populations. | among nine laboratory shrew lines originating from the japanese islands (nag, tok, tku, ize, tr and oki lines), west java (bog), bangladesh (ban) and sri lanka (sri), nag, tr and bog were fixed with amy-1b and sri with amy-1a. the remaining lines were still highly polymorphic with the two alleles. a new electrophoretic band c was found in the ban line and concluded to be expressed by a codominant allele, amy-1c, which was carried by a single heterozygous female from among eleven wild shrews of t ... | 1988 | 3260870 |
| seasonal and hormone-induced changes in testicular functions of the musk shrew suncus murinus l. | 1988 | 3169851 | |
| an electron microscopical observation of the endoneurial mast cells of the laboratory musk shrew: suncus murinus). | histochemical and ultrastructural properties of endoneurial mast cells of the normal and histamine liberator compound 48/80 (48/80)--injected musk shrew, suncus murinus (suncus) were examined by light and electron microscopies. it was observed that the normal mast cells contained numerous cytoplasmic granules, with dense and irregular dense cores, covered at times with slender microvilli. the cells were diffusely located within the endoneurial sheath of the peripheral nerve fibers and in the int ... | 1988 | 3400880 |
| hormonal correlates of sexual behavior in the female musk shrew: the role of estradiol. | plasma levels of several steroid hormones in the female musk shrew, (suncus murinus), are reported along with experiments on the causational role steroids play in female sexual behavior. gonadally intact females sampled directly after a brief (about 7 minutes on average) sexual interaction with a male had equivalent plasma levels of estradiol (e2) but significantly higher plasma progesterone (p4) levels than resting females. in experiment 2, females that engaged in nonsexual activities with cons ... | 1988 | 3237803 |
| alanine:glyoxylate aminotransferase activities in liver of suncus murinus (insectivora). | 1. the distribution of l-alanine:glyoxylate aminotransferase (agt) activities were found in suncus liver, 55% in particulate fraction and 45% in supernatant. 2. 65% of agt activities in particulate were dependent on agt isoenzyme 2 (agt 2) having molecular weight 210,000, the remainder (35%) of agt activities were dependent on agt isoenzyme 1 (agt 1) which have aminotransferase activity for serine. agt activities in supernatant were dependent on agt 1, agt 2 and alanine:2-oxoglutarate aminotrans ... | 1988 | 2907870 |
| reproductive response of a tropical mammal, the musk shrew (suncus murinus), to photoperiod. | musk shrews (suncus murinus) were maintained for 8 weeks in long (16 h light:8 h darkness) or short (8 h light:16 h darkness) daylengths. males housed in short daylength had significantly lighter androgen-dependent sex accessory organs than did males kept in long daylengths. this same trend was noted in male sexual behaviour. however, the weights of the testes and epididymides and sperm numbers did not differ. females housed in short daylengths had significantly lighter cervices and were less li ... | 1987 | 3430473 |
| suncus murinus: a new experimental model in emesis research. | effects of various emetic and antiemetic drugs were studied using suncus murinus for its potential use as an experimental model in emetic research. subcutaneous injection of nicotine bitartrate (10-15 mg/kg), veratrine sulfate (0.5-1.0 mg/kg), emetine dihydrochloride (40-80 mg/kg) and oral administration of copper sulfate (20-100 mg/kg) caused dose-dependent emesis in suncus. the ed50 of nicotine, veratrine, emetine and copper sulfate were 7.9, 0.4, 47.6 and 21.4 mg/kg, respectively. however, su ... | 1987 | 3600192 |
| genetic differentiation between laboratory lines of the musk shrew (suncus murinus, insectivora) based on restriction endonuclease cleavage patterns of mitochondrial dna. | the cleavage patterns of mitochondrial dna (mtdna) by 17 restriction endonucleases were compared between eight lines of musk shrews derived from different wild-caught stocks. enzymatic digestion by bamhi, pvuii, xbai, and xhoi showed a cleavage pattern common to all lines that were from five japanese islands (nag, ize, oki, tku, and tr), bangladesh (ban), sri lanka (sri), and java (bog), and every line lacked cleavage sites for sali and smai. different cleavage patterns were detected by the rema ... | 1987 | 3039974 |
| role of the ovary and adrenal gland in the sexual behavior of the musk shrew, suncus murinus. | the contributions of the ovary and the adrenal gland to sexual behavior were examined in the female musk shrew (suncus murinus). ovariectomy eliminated sexual behavior, and treatment with estradiol or testosterone restored it in almost all shrews. progesterone was ineffective in this regard. adrenalectomy, likewise, blocked sexual behavior in most females with intact ovaries. taken together, these results suggest that sexual behavior in this primitive eutherian mammal is normally modulated by se ... | 1987 | 3593838 |
| gonadal influences on sexual behavior in the male musk shrew (suncus murinus). | in this series of experiments the hormonal bases for male copulatory behavior in the musk shrew (suncus murinus) were examined. male musk shrews failed to show copulatory behavior after castration. testosterone replacement fully reinstated sexual behavior. males castrated at birth, and tested as adults after receiving testosterone implants, did not show male-typical sexual behavior. it appears that the gonads are essential for the regulation of male sexual behavior in this primitive mammal. | 1987 | 3557329 |
| serum constituents and liver photomicrographs of wild suncus murinus in the south of taiwan. | serum constituents and liver of the wild male suncus as well as of those bred and fed in our laboratory were examined serologically and histologically. the following results were obtained: the serum glutamic-oxaloacetic transaminase, gamma-glutamyl transaminase, inorganic phosphate, blood urea nitrogen, creatinine, uric acid, and zinc turbidity test levels of wild suncus were higher than those of 4 and 8 week old fed suncus. the total cholesterol level of wild suncus was lower than those of 4 an ... | 1987 | 2880742 |
| cats--source of protection or infection? a case-control study of hemorrhagic fever with renal syndrome. | in the first case-control study analyzing risk factors in sporadic hemorrhagic fever with renal syndrome, 111 cases occurring in shanghai in 1983 and 1984 and 136 matched controls were studied. three factors were associated with risk of disease: travel in the month before onset of illness, intense exposure to rodents in the home, and cat ownership. risk associated with cat ownership was not confounded by exposure to rodents in the home. neither cat ownership nor risk associated with rodent expos ... | 1987 | 2889355 |
| a new experimental animal for the study of age-related changes in serotonergic neuronal activity in the brain cortex. | calcium uptake by the cortical synaptosomes in a rodent (fischer rat) and an insectivore shrew (suncus murinus) was detected as a parameter reflecting molecular dysfunction of the aging brain. the change in calcium uptake by the cortical synaptosomes in both species was concomitant which showed less than half the capacity at 24 months old animals compared with those at 8 months old. on the other hand, 5-hydroxytryptamine binding and imipramine binding to the membrane fraction of aging rat brain ... | 1987 | 3574597 |
| morphological and reproductive characteristics of musk shrews (suncus murinus) collected in bangladesh, and development of the laboratory line (ban line) derived from them. | to establish a unique laboratory line of the musk shrew with different genetic properties from previously developed laboratory lines, 49 male and 49 female shrews were captured in the campus of bangladesh agricultural university from october through november in 1983 and from december in 1985 to january in 1986. the shrews collected were of various ages. they had light gray coats, with slight variations in color. except for the 12 shrews introduced into our laboratory, the total length and body w ... | 1987 | 3678369 |
| ouabain susceptibility of heart muscle of the house musk shrew, an insectivore: a comparison with the rat, guinea pig and rhesus monkey. | the susceptibility to ouabain of the heart muscle of the house musk shrew (suncus murinus), an insectivore, was investigated by means of in vitro experimentation, and compared with the rat, guinea pig, and rhesus monkey. contraction of the electrically driven heart muscles of all species slowly increased following application of ouabain. the shrew was approximate 100-fold more sensitive than the rat and 10-fold less than the guinea pig and rhesus monkey. only the rat heart preparation that was a ... | 1987 | 3694428 |
| anatomy and histology of the musk shrew (suncus murinus) prostate. | gross anatomy and the light and electron microscopic characteristics of the musk shrew (suncus murinus, insectivora) prostate are described. the prostate is a pair of compound tubuloalveolar glands with one main excretory duct for each gland. each gland is divided into ventral and dorsal lobes. the tubuloalveoli are larger in diameter and the secretory cells are lower in the ventral than in the dorsal lobes. probable spontaneous release of secretory granules and accumulation of secretory materia ... | 1986 | 3703747 |
| serum constituents of suncus murinus. | blood samples were collected by cardiac puncture from nine-week-old suncus, mice and rats those had been fasted for 16 hours, and the serum was assayed for the levels of corticosterone, cortisol, and other constituents. the following results were obtained: the serum levels of corticosterone and cortisol and corticosterone/cortisol ratio of suncus were about the same as those of human. the sgpt, gamma-gt, alp, ldh, ca and k values in suncus were all within the normal range of the respective value ... | 1986 | 3709676 |
| acute hepatotoxicity induced by hepatotoxins in suncus murinus. | a comparative study was conducted to contrast the hepatotoxicity of several chemicals in the musk shrew (suncus murinus) versus other common laboratory species (mouse or rat), and the following results were obtained from serum enzymes (sgot and sgpt) and histopathological findings of liver specimens. the sensitivity of suncus liver to ccl4 was different from that of mouse liver. the sensitivity of suncus liver to beta-d-galactosamine was weaker than that of rat liver. the sensitivity of suncus l ... | 1986 | 3735458 |
| detection of lymphocytic choriomeningitis virus antibody in colonies of laboratory animals in japan. | indirect fluorescent antibody method was applied for a detection of lymphocytic choriomeningitis virus (lcmv) antibody in colonies of laboratory animals in japan. the results showed that the antibody exist in spf mice (3/152, 2.2%) and conventional mice (30/539, 5.6%) with the titers ranging from 1:10 to 1:160. the antibody was also detected in 2.2% (2/89) of syrian hamsters, and 2.9% (2/68) of apodemus agrarius, 21.4% (3/14) of japanese harvest mice which have been maintained as laboratory colo ... | 1986 | 3525200 |
| studies on shrew (suncus murinus) epidermal growth factor. | the shrew smg contains a very high level of egf. by heterologous radioreceptor assay, the egf content was determined to be about 300 pmol/mg wet weight in the male. the content is sex dependent; in the female gland, it is only 4% of the male gland level. egf level and egf receptor content in other tissues showed a reciprocal distribution pattern with the parotid gland containing the second highest level of egf and the liver containing the largest amount of egf receptor. shrew egf is heat stable. ... | 1986 | 3008480 |
| biochemical and immunological characterization of suncus murinus mammary tumor virus dna polymerase. | enzymological properties of the rna-directed dna polymerase associated with the suncus murinus mammary tumor virus (sm-mtv) was investigated and its antigenic relatedness to other retroviral dna polymerases was examined. the enzyme exhibited higher activity in the presence of mg2+ than in the presence of mn2+ with endogenous rna as well as with almost all of the synthetic template x primers tested. mg2+ was also effective with poly(2'-o-methylcytidylate) x oligodeoxyguanylate which was known to ... | 1986 | 2417416 |
| ultrastructural characterization of the retrovirus particles (sm-mtv) liberated from the mammary tumor cell line (sm-mt) of a house musk shrew, suncus murinus (insectivora). | detailed ultrastructure of a new type of retrovirus (sm-mtv) released by cultured cells (sm-mt) of a spontaneous mammary tumor from a house musk shrew suncus murinus, insectivora, is described. the virus particles were revealed as three forms: intracellular; budding; and extracellular. the intracellular type a particles were similar in profile to those associated with mouse mammary tumor cells and tended to form a small cluster of several particles in the cytoplasm. in addition, horseshoe-shaped ... | 1986 | 2421890 |
| pharmacological characteristics of the contractile response of the vas deferens in shrews (suncus murinus). | 1986 | 3821064 |