Publications

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the growth of clostridium septicum and its inhibition. 194716561290
case report of sudden death [multiple clostridium septicum emboli in intrahepatic portal veins, with extensive necrosis of the liver]. 194718906905
parallelism in the lethal and hemolytic activity of the toxin of clostridium septicum.the relation of the lethal toxin to the hemolysin produced by clostridium septicum, strain 44, has been investigated. the following results suggest that the hemolytic and lethal actions of crude toxin are functions of a single substance or that they are functions of two substances which have similar physical, chemical, and antigenic properties. (1) within the limits of experimental error, the lethal activity of cultures is directly proportional to their hemolytic activity. (2) treatment of a cul ...194419871418
nutritional requirements and factors affecting the production of toxin of clostridium septicum.a medium consisting of a complete acid hydrolysate of casein supplemented with cystine, tryptophan, growth accessory factors, glucose, and inorganic salts, has been developed for the cultivation of clostridium septicum. toxin equivalent to 400 to 700 l.d(50) per ml. has been obtained regularly in this medium. the principal factors found to affect the yield of toxin are:- (a) phase of strain employed: cultures of cl. septicum may contain a number of variants. some of these may be characterized by ...194419871419
kinetics of lysis by clostridium septicum hemolysin.the kinetics of the hemolytic reaction effected by the hemolysin of clostridium septicum, strain 44, has been studied with regard to the effect of concentration, temperature, and hydrogen ion concentration on the rate of the hemolytic reaction. the kinetics of hemolysis was found to resemble in several respects that of enzyme-catalyzed reactions, but differed in the absence of a clearly defined ph optimum. attention is drawn to differences between the hemolytic system studied and certain other h ...194419871420
studies upon growth phases of clostridium septicum. 193516559834
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