Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| powdered milk micellar casein prevents oral colonization by streptococcus sobrinus and dental caries in rats: a basis for the caries-protective effect of dairy products. | three animal studies were performed to investigate the influence of the macromolecular structure of milk casein on caries incidence and the possible ecological changes of the oral microbiota by such casein fractions. towards this end, rats were infected with mixed bacterial suspensions of streptococcus sobrinus omz 176 and actinomyces viscosus ny1. various milk protein fractions were incorporated into carefully balanced powdered cariogenic diets to constitute the sole major protein component. di ... | 1999 | 10529530 |
| [effect of subinhibitory concentrations of various antimicrobials on insoluble glucan production, polystyrene adherence and bacterial surface hydrophobicity of streptococcus sobrinus]. | the effect of subinhibitory concentrations (1/2, 1/4, 1/8 of the mic) of amoxicillin, teicoplanin, clindamycin and erythromycin on the factors influencing the adherence and pathogenicity of streptococcus sobrinus was evaluated. these factors included insoluble glucan, polystyrene adherence and bacterial surface hydrophobicity. insoluble glucan was detected using a spectrophotometric method; polystyrene adherence was assessed using microtiter plates; and surface hydrophobicity was determined usin ... | 1999 | 10878518 |
| insoluble glucans synthesized by cariogenic streptococci: a structural study. | of the three cariogenic streptococci grown in four various culture media, the strain streptococcus mutans 20,381 was found to produce large amounts of extracellular glucosyltransferase and water-insoluble, adhesive exopolysaccharide when grown in batch culture on brain-heart infusion broth. methylation and nuclear magnetic resonance analyses revealed that the insoluble polymers synthesized by the crude glucosyltransferase preparations were mixed-linkage (1-->3), (1-->6)-alpha-d-glucans (so-calle ... | 1999 | 10520271 |
| topical antimicrobial therapy. | 1999 | 10355004 | |
| effect of matrix placement on furcation perforation repair. | furcation perforations are a serious complication during endodontic treatment, and a matrix to aid placement of repair material has been recommended. this study tested the sealing ability of amalgam and ketac silver placed with and without plaster of paris as a matrix. a bacterial penetration technique was used to test the seal. perforations created in the pulpal floor of extracted human mandibular molars were repaired as follows: group 1, amalgam; group 2, amalgam plus plaster as a matrix; grou ... | 1999 | 10321186 |
| enhanced (+)-catechin transglucosylating activity of streptococcus mutans gs-5 glucosyltransferase-d due to fructose removal. | the (+)-catechin transglucosylating activities of several glucosyltransferases (gtfs) from the genus streptococcus were compared. for this purpose, a mixture of four gtfs from streptococcus sobrinus sl-1 and recombinant gtf-b and gtf-d from streptococcus mutans gs-5 expressed in escherichia coli were studied. it was shown that after removal of alpha-glucosidase activity, gtf-d transglucosylated catechin with the highest efficiency. a maximal yield (expressed as the ratio of moles of glucoside fo ... | 1999 | 10473427 |
| effects of bovine immune and non-immune whey preparations on the composition and ph response of human dental plaque. | colostral products from non-immunized cows (cp) and cows immunized with mutans streptococci (ip) were used as mouth rinses in a short-term human study. the acidogenic potential of the products was tested and found to be negligible in vivo before application to subsequent rinsing tests. at first, all the participants received a professional tooth cleaning, after which they rinsed with one of the solutions (ip; cp; water) three times per day for 3 d. after each rinsing period, the resting ph and d ... | 1999 | 10467939 |
| antibacterial synergistic effect of chlorhexidine and hydrogen peroxide against streptococcus sobrinus, streptococcus faecalis and staphylococcus aureus. | chlorhexidine (chx) and hydrogen peroxide (hp) are potent antibacterial agents that are used in controlling dental plaque. however, both agents bear undesired side-effects. we have tested the hypothesis that an antibacterial synergistic effect can occur between the two agents against streptococcus sobrinus, streptococcus faecalis and staphylococcus aureus. we have found that at several combinations of hp and chx an antibacterial synergistic effect does occur, while at other combinations a on-sig ... | 1999 | 10080313 |
| investigation of the role of human breast milk in caries development. | the objective of this study was to determine the caries-related risk associated with human breast milk (hbm). | 1999 | 10197331 |
| structure and enzymatic properties of genetically truncated forms of the water-insoluble glucan-synthesizing glucosyltransferase from streptococcus sobrinus. | glucosyltransferase-i (gtf-i: 175 kda) of a cariogenic bacterium, streptococcus sobrinus 6715, mediates the conversion of water-soluble dextran (alpha-1,6-glucan) into a water-insoluble form by making numerous alpha-1,3-glucan branches along the dextran chains with sucrose as the glucosyl donor. the structures and catalytic properties were compared for two gtf-i fragments, gtf-i' (138 kda) and gs (110 kda). both lack the n-terminal 84 residues of gtf-i. while gtf-i' still contains four of the si ... | 1999 | 10423519 |
| recolonisation pattern of mutans streptococci after suppression by three different modes of chlorhexidine gel application. | clinical studies have shown conflicting results for the reduction of approximal caries when chlorhexidine gel has been applied either in trays or by flossing. to investigate whether these modes of treatment affect the colonization of mutans streptococci (ms) differently, we quantified ms in saliva and on various tooth surfaces before and after a single chlorhexidine gel application. twenty-one schoolchildren (15-16 yr old), with high numbers of salivary ms, were randomised into three groups. the ... | 1999 | 10424380 |
| a new mechanism of action of fluoride on streptococci. | addition of fluoride to the growth medium of streptococcus sobrinus resulted in a loss of glucan-binding lectin activity. upon removal of fluoride, the bacteria regained their ability to bind glucan in about one generation. chloramphenicol prevented recovery of ability to produce the lectin, showing the requirement for protein synthesis. fluoride also caused a significant reduction in the tendency of the streptococci to form chains of cells, although the spent medium from fluoride-containing gro ... | 1999 | 10434061 |
| effect of apis mellifera propolis from two brazilian regions on caries development in desalivated rats. | the purpose of the present study was to evaluate the effect of apis mellifera propolis collected from two regions of brazil on caries development in desalivated rats. ethanolic extracts of propolis (eep) were prepared from crude propolis samples collected in minas gerais state (mg), southeastern brazil, and rio grande do sul state (rs), southern brazil. the flavonoid composition of eep was analyzed by high-performance thin-layer chromatography (hptlc) and reversed-phase high-performance liquid c ... | 1999 | 10460964 |
| secretory immunity in defense against cariogenic mutans streptococci. | specific immune defense against cariogenic mutans streptococci is provided largely by salivary secretory iga antibodies, which are generated by the common mucosal immune system. this system is functional in newborn infants, who develop salivary iga antibodies as they become colonized by oral microorganisms. the mechanisms of action of salivary iga antibodies include interference with sucrose-independent and sucrose- dependent attachment of mutans streptococci to tooth surfaces, as well as possib ... | 1999 | 9831775 |
| a dna probe specific to streptococcus sobrinus. | three dna fragments (ssb-1, -2 and -3) in the dextranase gene (dex) of streptococcus sobrinus were amplified by polymerase chain reaction and used as dna probes. the probes were examined for the specificity and the sensitivity of hybridization with dna of oral streptococcal species. while probes ssb-1 and ssb-2 were specific to both s. sobrinus and streptococcus downei, ssb-3 was specific only to s. sobrinus. ssb-3 was able to detect 5 ng of chromosomal dna purified from s. sobrinus nidr6715 and ... | 1999 | 10551167 |
| effects of topical application of free and liposome-encapsulated lactoferrin and lactoperoxidase on oral microbiota and dental caries in rats. | four groups of rats were inoculated with streptococcus sobrinus atcc 33478 and fed a cariogenic diet for 42 days. topical treatment with either distilled water, sodium fluoride (0.2%), a solution containing lactoferrin and lactoperoxidase, or a solution containing liposome-encapsulated lactoferrin and liposome-encapsulated lactoperoxidase was applied at intervals for 35 days. caries incidence in groups treated with liposome-encapsulated lactoferrin and lactoperoxidase was significantly lower tha ... | 1999 | 10580537 |
| fluoride release and antibacterial properties of new-generation tooth-colored restoratives. | the aim of this study was to compare the amounts and pattern of fluoride release and antibacterial properties of new-generation restoratives over a 35-day period. materials evaluated included fluoride-releasing composites (tetric, experimental x), compomers (dyract, compoglass), and a resin-modified glass-ionomer cement (fuji ii lc). a conventional glass ionomer (fuji ii cap) was used as a control for fluoride-release testing. five samples of each restorative material were evaluated for daily fl ... | 1999 | 10823077 |
| in vitro antibacterial effect of rc-prep components on streptococcus sobrinus. | the aim of this study was to examine the bacteriostatic and bactericidal effects of the components of rc-prep: edta, urea peroxide and glycol. the minimal inhibitory concentration and the minimal bactericidic concentration of edta, urea peroxide and glycol were tested on the viability of streptococcus sobrinus (s. sobrinus). the combined antibacterial effect of these components was also examined on s. sobrinus. the minimal inhibitory concentration of edta was found to be 0.125%, of urea peroxide ... | 1999 | 10815566 |
| immunolabeling of the major cell surface protein antigen of streptococcus sobrinus with monoclonal antibody. | the purpose of this study was to determine the accessibility of monoclonal antibody (mcab), specific for the major cell surface protein antigen (pag) of streptococcus sobrinus, to the surface of its native epitopes. | 1999 | 10863403 |
| tonsillar application of formalin-killed cells of streptococcus sobrinus reduces experimental dental caries in rabbits. | living streptococcus sobrinus cells were orally inoculated into nonimmune rabbits and rabbits immunized with formalin-killed cells of s. sobrinus through tonsillar application to examine the anticaries potential of this method of immunization. the living s. sobrinus cell numbers and the caries areas in the rabbits immunized by tonsillar application decreased to a level one-fifth of that in nonimmune rabbits. | 1999 | 9864248 |
| litter effects on caries in rats and implications for experimental design. | the purpose of this study was to obtain quantitative estimates of litter effects on caries development in rats and to examine the implications for design of rat caries experiments. twelve female sprague-dawley rats, aged 60 days, were bred with 4 male rats. nine of the 12 dams had litters in close proximity. the litters were culled to 10 pups. one pup from each litter was placed with each of the other dams for nursing, leaving 2 pups from each litter with the birth dam. this design allowed the l ... | 1999 | 9892785 |
| the specific genes for lantibiotic mutacin ii biosynthesis in streptococcus mutans t8 are clustered and can be transferred en bloc. | mutacin ii is a ribosomally synthesized peptide lantibiotic produced by group ii streptococcus mutans. dna sequencing has revealed that the mutacin ii biosynthetic gene cluster consists of seven specific open reading frames: a regulator (mutr), the prepromutacin structural gene (muta), a modifying protein (mutm), an abc transporter (mutt), and an immunity cluster (mutfeg). transformations of a non-mutacin-producing strain, s. mutans ua159, and a mutacin i-producing strain, s. mutans ua140, with ... | 1999 | 10049909 |
| simultaneous induction of specific immunoglobulin a--producing cells in major and minor salivary glands after tonsillar application of antigen in rabbits. | the immunoglobulin a (iga)-producing cells in the stroma of major salivary glands are induced by antigenic stimulation of the mucosal immune system. whether such cells also are induced in minor salivary glands by this stimulation remains to be determined. after application of sheep red blood cells to the palatine tonsils every 3 days for 6 weeks, anti-sheep red blood cell iga was detected in saliva both by agglutination tests and by enzyme-linked immunosorbent assay. using enzyme-linked immunosp ... | 1999 | 10204476 |
| effect of oleanolic acid-cyclodextrin inclusion compounds on dental caries by in vitro experiment and rat-caries model. | earlier work in vitro showed that oleanolic acid (oa) was a potential inhibitor of insoluble glucan (isg) synthesis from mutans streptococci (ms). in this study, two oleanolic acid-cyclodextrin inclusion compounds (oa-cds), oleanolic acid-g1-beta-cyclodextrin (oa-g1-beta cd) and oleanolic acid-beta-cyclodextrin (oa-beta cd), were assayed for their effects on isg synthesis from streptococcus mutans mt8148r, and on the growth of oral bacteria. oa-beta cd inhibited isg synthesis by 55.3 and 37.4% a ... | 1999 | 10413873 |
| effect of salivary biofilm on the adherence of oral bacteria to bleached and non-bleached restorative material. | the objective of this work was to examine the effect of in vitro salivary biofilm on the adherence of oral bacteria to bleached and non-bleached restorative material (charisma). | 1999 | 10483391 |
| colostral proteins from cows immunised with streptococcus mutans/s. sobrinus support the phagocytosis and killing of mutans streptococci by human leucocytes. | passive immunisation, based on bovine colostral preparations, is an area of active research. specific bovine antibodies inhibit the virulence factors of target pathogens but the interactions between whey preparations and human immune defence cells are not well known. bovine colostrum inhibits the phagocytic activity of bovine leucocytes and this may reflect the biological activity of immunoglobulins in it. therefore, this study aimed to examine the effects of bovine whey protein preparations fro ... | 1999 | 10510968 |
| studying biofilm formation of mutans streptococci. | 1999 | 10547815 | |
| effects of monoclonal antibody on colonization of streptococcus sobrinus and development of dental caries in rats. | to investigate the effect of local application of monoclonal antibody (mcab) raised against the 210kd cell surface protein antigen (pag) of streptococcus sobrinus on the colonization of rats' teeth and the development of dental caries. | 1999 | 10557177 |
| effects of continuous glucocorticoid infusion on the progression of dentinal caries in growing rats. | this study was undertaken to test the effects of a low dose of continuous glucocorticoid infusion on the rate of progression of dentinal caries in molars of young rats. forty-seven rats were inoculated in the mouth with streptococcus sobrinus and fed ad libitum a cariogenic diet and 10% sweetened water. after 10 days of caries initiation ten animals were killed to serve as a reference group. in the rest of the animals the cortisone or placebo pellet was implanted subcutaneously in the back of th ... | 1998 | 9860095 |
| concentrated bovine colostral whey proteins from streptococcus mutans/strep. sobrinus immunized cows inhibit the adherence of strep. mutans and promote the aggregation of mutans streptococci. | the aim of this study was to examine the effect of bovine colostral whey proteins from cows immunized with streptococcus mutans/strep. sobrinus on the adherence and aggregation of caries-inducing bacteria, i.e., mutants streptococci. both adherence and aggregation are important phenomena in the bacterial colonization of the human oral cavity. in all adherence experiments there was a significant difference between treatments by immune product (ip; from immunized cows) and a control product (cp; a ... | 1998 | 9839215 |
| root caries and some related factors in 88-year-old carriers and non-carriers of streptococcus sobrinus in saliva. | the prevalence of caries on exposed root surfaces in 88-year-old subjects with and without salivary levels of streptococcus sobrinus was studied. ninety-two individuals were examined with regard to root caries lesions and fillings. the root caries index (rci) was calculated and related to salivary flow rate and buffer capacity, plaque score and salivary counts of streptococcus mutans, s. sobrinus and lactobacilli. in 89 subjects with exposed root surfaces, all but 2 harbored mutans streptococci; ... | 1998 | 9544856 |
| comparison of the cariostatic effects between regimens to administer oolong tea polyphenols in spf rats. | the cariostatic effect of oolong tea polyphenols administered according to several regimens was examined in specific pathogen-free (spf) sprague-dawley rats given both a diet containing 20% sucrose and infected with s. sobrinus 6715. the crude preparation (ote) of oolong tea polyphenols showed the most prominent effect on caries reduction in spf rats when ote was administered in the drinking water beginning 1 day prior to the inoculation of s. sobrinus 6715, when compared with chromatographicall ... | 1998 | 9438575 |
| effects of various resin composite (co)monomers and extracts on two caries-associated micro-organisms in vitro. | previous studies have shown that extracts of various filling materials, e.g., resin composites, may influence the growth of cariogenic micro-organisms. the purpose of this study was to examine the effects of important resin composite (co)monomers (bis-gma, udma, tegdma, egdma) and extracts of two commercial dental composites with similar composition (composite a, arabesk; composite s, superlux) on the growth of the two cariogenic bacterial pathogens streptococcus sobrinus and lactobacillus acido ... | 1998 | 9437400 |
| ecological study of streptococcus mutans, streptococcus sobrinus and lactobacillus spp. at sub-sites from approximal dental plaque from children. | previous immunofluorescence (if) studies have indicated that streptococcus mutans may preferentially colonise specific sub-sites within approximal plaque. the present study aimed to extend these observations to other mutans streptococci and lactobacilli in such gingival margin plaque. two hundred and seventy approximal plaque samples were taken from 90 teeth (3 from each tooth) in 64 children; three gingival margin sub-sites in relation to the contact area: away from (a), to the side of(s) and b ... | 1998 | 9438572 |
| combined inhibitory effect of bovine immune whey and peroxidase-generated hypothiocyanite against glucose uptake by streptococcus mutans. | immune whey product was obtained from streptococcus mutans- and streptococcus sobrinus-immunized cows. hypothiocyanite (hoscn/oscn-) was generated in vmg-buffer, ph 5.5 or 6.5, by bovine milk lactoperoxidase, kscn and hydrogen peroxide. the glucose incorporation by late-log cells of s. mutans 10449, serotype c, was followed by measuring the uptake of 14c-glucose at 37 degrees c. at ph 5.5 and 6.5 both immune whey product and hoscn/oscn- dose-dependently inhibited glucose uptake. the inhibition b ... | 1998 | 9872115 |
| mutacin production by streptococcus mutans may promote transmission of bacteria from mother to child. | the production of bacteriocin-like inhibitory substances, mutacins, by mutans streptococci varies among isolates. to find if the degree of mutacin activity of an isolate was related to its transmission between mother and her child, 19 mothers and their 18-month- to 3-year-old children were sampled for their oral mutans streptococci. in addition, the stability of mutacin activity was studied with isolates from the mothers and with isolates from five unrelated 5-year-old children in 5- to 7-year f ... | 1998 | 9596721 |
| study of root caries in an artificial mouth. | the object of this project was to develop a laboratory model system to study root and enamel caries. model plaque biofilms containing consortia of four (streptococcus mutans, streptococcus sobrinus, actinomyces naeslundii, and lactobacillus rhamnosus) or six (s mutans, s sobrinus, s mitis, a naeslundii, l rhamnosus, and veillonella dispar) species of caries pathogens were developed in a artificial mouth. caries lesions similar to those found in vivo were produced on enamel and dentine blocks and ... | 1998 | 9676475 |
| structural and antigenic characteristics of streptococcus sobrinus glucan binding proteins. | three purified glucan binding proteins (gbp-2, gbp-3, and gbp-5) from streptococcus sobrinus 6715 were compared structurally by mass spectroscopy of tryptic fragments and antigenically by western blot analysis with rat antisera to each gbp or to peptides containing putative glucan binding epitopes of mutans streptococcal glucosyltransferases. structural and antigenic analyses indicated that gbp-3 and gbp-5 are very similar but that both are essentially unrelated to gbp-2. none of these s. sobrin ... | 1998 | 9784575 |
| acid-regulated proteins induced by streptococcus mutans and other oral bacteria during acid shock. | our previous research has demonstrated that with the more aciduric oral bacteria, an acid shock to sub-lethal ph values results in the induction of an acid tolerance response that protects the cells at extremely low ph (ph 3.0-4.0) that kills unadapted control cells maintained at ph 7.5 (oral microbiol immunol 1997: 12: 266-273). in this study, we were interested in comparing the protein profiles of acid-shocked and control cells of nine organisms from three acid-ogenic genera that could be cate ... | 1998 | 9807121 |
| whole-cell protein electrophoretic analysis of viridans streptococci: evidence for heterogeneity among streptococcus mitis biovars. | one hundred reference strains representing all species belonging to the different phylogenetic lineages of the viridans streptococci were examined by means of one-dimensional whole-organism protein electrophoresis. for most of the species examined, multiple strains characterized by dna-dna hybridization were included and, wherever described, representatives of different biochemical variants were analysed. most species were clearly differentiated. the data support the viewpoint that members of th ... | 1998 | 9542082 |
| extraction, assay, and analysis of antimicrobials from plants with activity against dental pathogens (streptococcus sp.) | many dental and periodontal diseases are largely a question of bacterial etiology. dental caries develop due to an increase of strongly acidogenic and aciduric gram-positive bacteria while common forms of periodontal disease are linked to anaerobic gram-negative bacteria in subgingival plaque. many plants and plant-derived antimicrobial components are used in folklore therapeutics for the treatment of periodontal disorders and for the purposes of oral hygiene. some have been evaluated for possib ... | 1998 | 9553834 |
| in vitro assessment of the antimicrobial activity of a local sustained release device containing amine fluoride for the treatment of oral infectious diseases. | dental caries and periodontal diseases are chronic infectious diseases caused by oral bacteria. local sustained release delivery systems extend the time in which the drug is present in the oral cavity, thus enhancing its therapeutic potential while reducing its side effects. amine-fluorides (amf) are known anticaries agents and have recently been found to have an antibacterial effect against periodontal pathogens and caries-associated bacteria. the purpose of this in vitro study was to assess th ... | 1998 | 9554175 |
| stabilization of the glucan-binding lectin of streptococcus sobrinus by specific ligand. | cell suspensions of streptococcus sobrinus can be aggregated by high molecular-weight alpha-1,6 glucans. the aggregation depends on the fidelity of a cell wall-bound, glucan-binding lectin (gbl). it is thought that the lectin may play a part in the sucrose-dependent accretion of streptococci in dental plaques. results showed that the anionic detergent, sodium dodecyl sulphate (sds) was a potent inhibitor of the lectin. when cells were incubated in sds and washed to remove the detergent, lectin a ... | 1998 | 9569988 |
| rapid isolation of chromosomal dna from oral streptococci and polymerase chain reaction-oriented restriction fragment-length polymorphism analysis for genetic heterogeneity. | we have extensively modified the published method for the lysis of gram-positive bacteria to isolate chromosomal dna from only 1 ml of oral streptococcal overnight culture. cells were incubated with lysozyme and r nase a in the presence of polyethylene glycol. after centrifugation, cells were lysed with sodium dodecyl sulfate and proteinase k. following ethanol precipitation, sodium dodecyl sulfate solution was added to the residue, and the pellet was completely dispersed by incubating at 65 deg ... | 1998 | 9573816 |
| estimation of the caries-related risk associated with infant formulas. | baby bottle tooth decay (bbtd) affects 6% of children under three years of age and is associated with inappropriate bottle use. the objective of this study was to estimate the caries-related risk associated with 26 infant formulas and whole milk. | 1998 | 9866143 |
| demonstration of identical strains of mutans streptococci within chinese families by genotyping. | the aim of this study was to investigate the intra-familial distribution of mutans streptococci in some chinese families. eighteen families consisting of mother, father and a 3-yr-old child without any older siblings participated. clinical examination and interview were performed to obtain information about level of mutans streptococci in saliva, caries prevalence scored by dmft or deft, general health, diet regimens, breast-feeding time, principal caretaker of the child and the parents' profess ... | 1998 | 9672101 |
| the activation and function of host matrix metalloproteinases in dentin matrix breakdown in caries lesions. | matrix metalloproteinases (mmps) are a family of enzymes which, in concert, are capable of degrading collagen. we investigated whether human mmps could participate in the degradation of dentin organic matrix after demineralization. we performed western blot analyses using mmp-specific antibodies to identify mmps in human dental caries lesions. enzymography and functional activity assays, with 125i-labeled gelatin as substrate or quantitating the degradation of type i collagen, were used to deter ... | 1998 | 9719036 |
| bacterial adherence to bleached surfaces of composite resin in vitro. | the effect of bleaching agents on bacterial adherence to polished surfaces of composite resin restorations was assessed in vitro. | 1998 | 9830652 |
| the effects of fluoride concentration and the level of cariogenic challenge on caries development in desalivated rats. | dental caries is an infectious and transmissible disease that continues to affect the majority of people. the presence of carbohydrate, mainly sucrose in the diet, is an important factor in its occurrence. the amount of fluoride required for optimal protective effect where there is a high caries challenge is unclear. differences in the intensity of cariogenic challenge, for whatever reason, may play a part in determining fluctuations in the effectiveness of fluoride. the purpose of this study wa ... | 1998 | 9877322 |
| five-year incidence of caries, salivary and microbial conditions in 60-, 70- and 80-year-old swedish individuals. | the 5-year incidence of dental caries in a random sample of 60-, 70- and 80-year-old inhabitants of goteborg was related to salivary and microbial conditions. of the 208 persons examined at baseline, 148 (71%) participated in the follow-up examination; 69, 51 and 28, respectively, in the different age groups. the study revealed that 27% of the participants had not developed any carious lesions during the 5-year period and that the incidence of coronal and root caries increased with age. in the 6 ... | 1998 | 9577981 |
| comparison of dentin apposition and dentinal caries progression in the mandibular and maxillary molars of the rat. | to show that the rate and the rate of reduction of dentin apposition are about the same in mandibular and maxillary molars, 23 sprague-dawley rat pups were randomized into 2 groups on the day of birth. during lactation half of their dams received a standard rodent diet; the other half, a diet containing 41% sucrose. at the age of 3 weeks the pups were weaned, weighed, given an intraperitoneal injection of oxytetracycline hydrochloride, and inoculated with oral streptococcus sobrinus. during the ... | 1998 | 9860098 |
| sealing ability of furcation perforation repair. | 1998 | 11431824 | |
| inhibition of glucan synthesis by casein polymers crosslinked by glutaraldehyde. | glutaraldehyde-crosslinked α-casein polymers with molecular masses of 1-5×10(5) were found to inhibit adhesive insoluble glucan formation catalyzed by glucan synthases from streptococcus sobrinus b13, a cariogenic oral bacterium. of the three subcomponents of the glucan synthases tested, primer-dependent insoluble glucan synthase was inhibited specifically by the m r~2.7×10(5) polymer at a concentration of 1.4-8.5 μg/ml. the polymer was also active in inhibiting the artificial plaque formation b ... | 1998 | 27393366 |
| screening of antiadherent activity on streptococcus sobrinus culture. | the mutans group of streptococci is considered to play a key role in the etiology of dental caries. we have evaluated the ability of different substances to prevent dental plaque formation without affecting streptococcus sobrinus viability. viable organisms were detected as cfu/ml in agar plates and bacterial adherence was assessed by dry weight. we studied 23 compounds and we demonstrated that phenyl salicylate, phenylmercuric nitrate and potassium iodate are more effective to inhibit adhesion ... | 1997 | 11885077 |
| the phosphoenolpyruvate:sugar phosphotransferase system of oral streptococci and its role in the control of sugar metabolism. | oral streptococci are sugar-fermentative bacteria comprising at least 19 distinct species and are a significant proportion of the normal microbial population of the mouth and upper respiratory tract of humans. these streptococci transport several sugars by the phosphoenolpyruvate:sugar phosphotransferase system (pts) which concomitantly catalyzes the phosphorylation and translocation of mono- and disaccharides via a chain of enzymic reactions that transfer a phosphate group from phosphoenolpyruv ... | 1997 | 9050218 |
| [effects of sodium doecyl sulfate on the artificial dental plaque in chemostat]. | sodium doecyl sulfate (sds) is widely used as a detergent in dentifrices. it has been shown to interfere with the protein adsorption to hydroxyapatite (ha), and inhibit acquired pellicle formation. the aim of the present study was to examine the effects of sds on the artificial dental plaque in chemostat. the amount of the 3h-labelled bacteria adhered on the enamel fragment surface was determined with scintillometer. the artificial dental plaque was observed under the scanning electron microscop ... | 1997 | 11189307 |
| influence of iron alone or with fluoride on caries development in desalivated and intact rats. | sugar is used as a vehicle for iron fortification in communities where anemia is prevalent. the purpose of the present study was to investigate the relationship between caries experience and iron concentration in sugar fed to rats subjected to a severe cariogenic challenge. desalivated and intact animals were assigned to 4 different diet subgroups, 3 receiving iron sucrose (350, 175 and 88 ppm fe) and a control group. the influence of iron sugar combined with 10 ppm f in drinking water was explo ... | 1997 | 9165198 |
| assessing the cariogenic potential of some infant formulas, milk and sugar solutions. | using a desalivated rat model, the authors found that several commonly used infant formulas had significant cariogenic potential. sucrose was by far the most cariogenic and cows' milk the least cariogenic of all the products examined. the data show that dental practitioners and other health care professionals should discourage the use of sugar in baby bottles and provide information on which formulas are least likely to induce caries when continuous bottle feeding is unavoidable. | 1997 | 9231601 |
| fluoride and pilocarpine reduce the risk of caries produced by chronic clomipramine treatment in rats. | the effects of chronic clomipramine treatment on the incidence of caries in the rat and their prevention by fluoride and pilocarpine were investigated. one hundred and twenty male wistar rats were divided into six groups, five experimental groups, one control group and treated with 50 mg/kg/day of clomipramine, 10 ppm fluoride in drinking water, and 5 mg/kg/day of pilocarpine. all animals were infected with streptococcus sobrinus 6715 and fed a cariogenic diet ad libitum for 42 days. water and f ... | 1997 | 9118188 |
| cariostatic effect of aspartame in rats. | this study examined the effects of aspartame (apm) on caries and the streptococcus sobrinus population. six groups of rats (20 in each group) colonized with s. sobrinus were fed varying amounts of sucrose (su) and apm in their diets as follows: 1-0.15% apm, 2-0.30% apm, 3-30% su, 4-30% su + 0.15% apm, 5-50% su and 6-50% + 0.15% apm. ten from each group were sacrificed at 6 weeks and 10 at 12 weeks. s. sobrinus populations at both intervals were negligible in groups 1 and 2 and had no differences ... | 1997 | 8955999 |
| anti-bacterial action of onion (allium cepa l.) extracts against oral pathogenic bacteria. | in this study, the focus was on the antibacterial activity of onions. this study researched the activities of onion extracts on streptococcus mutans and streptococcus sobrinus, the main causal bacteria for dental caries, and porphyromonas gingivalis and prevotella intermedia, considered to be the main causal bacteria of adult periodontitis. the results showed that the onion extracts possess an effect on all test bacterial strains (s.mutans jc-2, s. sobrinus omz176, p. gingivalis atcc 33277 and p ... | 1997 | 9354029 |
| purification, and biochemical and biological characterization of an immunosuppressive and lymphocyte mitogenic protein secreted by streptococcus sobrinus. | an immunosuppressive/mitogenic (ism) protein was purified from the supernatants of cultures of streptococcus sobrinus with an isoelectric point of 4.75 and a relative molecular mass of 38 kda (p38). treatment of c57bl/6 mice with p38 induced an increase in the numbers of non-specific splenic ig-secreting plaque-forming cells (pfc) with peak responses on day 3 for igm-secreting pfc and on day 5 for igg-secreting pfc, with an isotype pattern consisting predominantly of igg2a and igg2b. this increa ... | 1997 | 9418134 |
| sugar metabolism by mutans streptococci. | 1997 | 9436320 | |
| inhibition by hop bract polyphenols of cellular adherence and water-insoluble glucan synthesis of mutans streptococci. | the inhibitory effect of hop bract polyphenols (hbp) on cariogenic streptococci was investigated. it was found that the high molecular weight polyphenol (estimated about 36,000-40,000) inhibited the cellular adherence of streptococcus mutans mt8148 (serotype c) and streptococcus sobrinus atcc 33478 (serotype g) at much small concentrations than the polyphenols extracted from oolong tea or green tea leaves. furthermore, hbp also inhibited the action of glucosyltransferase, which was involved in t ... | 1997 | 9058972 |
| generation of bovine immune colostrum against streptococcus mutans and streptococcus sobrinus and its effect on glucose uptake and extracellular polysaccharide formation by mutans streptococci. | due to potential side-effects of active immunization by cariogenic mutans streptococci, oral administration of passively-derived antibodies could be a more acceptable way to reduce colonization and virulence of these microorganisms in human dentition. the aim of this study was to produce antistreptococcal immunoglobulins into bovine colostrum and explore the possible antibacterial mechanisms of these immunoglobulins against mutans streptococci. specific serum igg antibodies to whole cell antigen ... | 1997 | 9286054 |
| thermophysiology of streptococcus mutans and related lactic-acid bacteria. | the temperature ranges for growth of streptococcus mutans gs-5 and s. sobrinus 6715 were found to be very narrow, from about 30 to 47 degrees c, with optimal growth around 37 degrees c. thus, the organisms showed little potential to grow in the environment outside of the animal host. in contrast wider ranges were found for enterococcus hirae, s. rattus and s. sanguis. detailed study of s. mutans gs-5 showed that energetic coupling, reflected in yields of biomass per mol of glucose utilized, were ... | 1997 | 9298187 |
| adherence of oral streptococci to an immobilized antimicrobial agent. | an antimicrobial agent, 3-(trimethoxysilyl)-propyldimethyloctadecyl ammonium chloride, was immobilized on silica. interaction between the material (termed) oais) and various oral bacterial species were then studied. seven species of streptococcus and two actinomyces were investigated for their ability to adhere to this biomaterial. cell-surface hydrophobicity and zeta-potential were examined as well. analysis of extracted hydrophobic proteins which adhered to oais revealed that the adherence of ... | 1997 | 9347116 |
| mutans streptococci and incipient caries adjacent to glass ionomer cement or resin-based composite in orthodontics. | levels of mutans streptococci in plaque adjacent to orthodontic brackets retained with a glass ionomer cement (gic) (ketac-cem) and a resin-based composite (cr) (concise) were investigated, using the split mouth technique in 11 patients who, before treatment, had more than 10(5) cfu of these microorganisms. after full-term orthodontic treatment (mean 9.5 months), the percentage of mutans streptococci of total cfu count in plaque was lower adjacent to gic-retained brackets (mean 3.9) than adjacen ... | 1997 | 9294355 |
| caries and plaque inhibition in rats by five topically applied dentifrices. | the effectiveness of 5 different brands of dentifrices on caries and plaque were tested in rats in 2 experiments. 10 litters of rats each were infected with streptococcus sobrinus omz-176 and actinomyces viscosus ny1. the rats were offered the diet 2000a containing either 40% of sucrose (study i) or 10% of sucrose (study ii). the following products were tested topically: (1) h2o, (negative control); (2) chlorhexidine diacetate, (positive control); (3) parodontax nf; (4) meridol; (5) colgate tota ... | 1997 | 9249193 |
| trends in dental health among icelandic urban children. | caries experience, oral hygiene and caries-related salivary parameters were recorded in a 20% representative sample of 12-year-old schoolchildren in reykjavik, iceland in 1991. the majority of the children was re-examined 3 years later in 1994. trends in prevalence of caries and salivary bacteria were assessed by comparison with an analogous earlier longitudinal study (1984-87). mean dfs values for 12-year-olds were 12.1 and 4.1, for 15-year-olds 23.3 and 11.3 in the earlier and later study, res ... | 1997 | 9249184 |
| high-level ability of secretory iga to block hiv type 1 transcytosis: contrasting secretory iga and igg responses to glycoprotein 160. | the igg and secretory iga (s-iga) responses to the hiv-1 envelope (gp160 antigen) were analyzed in the colostrum (col) and in the cervicovaginal fluid (cvf) of hiv-l-infected women. we show igg antibodies (abs) to the recombinant gp160 to be predominant as compared with the corresponding s-iga isotype. the low level of the s-iga response cannot be related to a general disturbance of the mucosal-associated iymphoid tissue (malt) because the level of a current ab to a caries-associated antigen fro ... | 1997 | 9310284 |
| immunogenicity and protective immunity induced by synthetic peptides associated with a catalytic subdomain of mutans group streptococcal glucosyltransferase. | we examined the immunogenicity and induction of protective immunity of two 19-mer sequences (ggy and and) which overlapped a highly conserved region which has recently been implicated in the enzymatic activity of glucosyltransferases (gtfs) of the mutans group streptococci. these peptides were synthesized as eight-branched constructs on a lysine core. serum immunoglobulin g (igg) antibody, induced by subcutaneous (s.c. [salivary gland vicinity]) injection with these peptide constructs, reacted w ... | 1997 | 9353015 |
| mutans streptococcal serotypes in children with gastroesophageal reflux disease. | it has been suggested that vomiting acid gastric contents in bulimia might favor oral growth of streptococcus sobrinus. we studied the colonization of streptococcus sobrinus (serotypes g and d) and streptococcus mutans (serotypes c, e and f) in sixteen children, ages five to fifteen years, who had suffered for four to eleven years from gastroesophageal reflux, another condition with recurrent acid regurgitation. our aim was to find out if the prevalence of streptococcus sobrinus would be higher ... | 1997 | 9262802 |
| chemical and functional properties of mutastein, an inhibitor of insoluble glucan synthesis by streptococcus sobrinus. | mutastein, a potent inhibitor of insoluble glucan synthesis by streptococcus sobrinus, is a protein with a molecular weight of approximately 2 x 10(6). amino acid and elisa analyses suggested that mutastein is a mixture of heterogenous polymers of alpha-casein contained in the culture medium of the producing strain, aspergillus terreus m3328. mutastein strongly inhibited the primer-dependent insoluble glucan synthase of s. sobrinus b13. the primer-independent soluble glucan synthase was not affe ... | 1997 | 9145515 |
| influence of fluoride co-cystallized with sugar on caries development in desalivated rats. | previous studies have shown that fluoride (f) administered concomitantly with sucrose in drinking water, in the diet, or alone is an effective cariostatic agent. the purpose of the present study was to determine the minimum concentration of f co-crystallized with sugar that may be used to prevent dental caries in rats subjected to a severe cariogenic challenge. desalivated sprague-dawley rats, infected with streptococcus sobrinus, were placed in a könig-höfer programmed feeder. the rats received ... | 1997 | 9222451 |
| caries-inducing activity of the hydrogenated derivative of an isomaltooligosaccharide mixture in rats. | the caries-inducing activity of the hydrogenated derivative of an isomaltooligosaccharide mixture (imo-h) was evaluated in vitro for its acidogenicity and in vivo an experimental caries system with specific-pathogen-free (spf) rats. streptococcus sobrinus 6715 (serotype g) did not produce a significant amount of acid from imo-h, whereas streptococcus mutans mt8148 (serotype c) gradually produced a small amount of acid, although the degree was less than that of sucrose. in vivo experiments were c ... | 1997 | 9301113 |
| tonsillar application of killed streptococcus mutans induces specific antibodies in rabbit saliva and blood plasma without inducing a cross-reacting antibody to human cardiac muscle. | when streptococcus mutans cells are injected into the skeletal muscle of rabbits, an antibody against human cardiac muscle, as well as an anti-s. mutans antibody, is induced in blood plasma. our previous study showed that when sheep erythrocytes are applied to palatine tonsils, an antibody against the applied cells is induced both in blood plasma and saliva. this antibody has no activity against cardiac muscle. it is not clear, however, if s. mutans application to the tonsils evokes an antibody ... | 1997 | 9353033 |
| adsorption of streptococcus sobrinus dextranase inhibitor to water-insoluble alpha-d-glucans of oral streptococci. | a low molecular weight dextranase inhibitor from streptococcus sobrinus has previously been identified and purified. the range of conditions under which inhibition occurs, and the situations in which dextranase activity of s. sobrinus can reappear, have been examined in the chemostat. these studies have revealed that when dextranase production exceeds that of the inhibitor, all the inhibitor is tightly bound into enzyme-inhibitor complexes, and the excess enzyme remains active. another factor th ... | 1997 | 9353584 |
| effects of a hydrogenated isomaltooligosaccharide mixture on glucan synthesis and on caries development in rats. | the caries inhibitory effect of the hydrogenated derivative of an isomaltooligosaccharides mixture (imo-h) was examined in vitro and in vivo experiments. imo-h could not be used as a substrate for the crude glucosyltransferases (gtases) of streptococcus sobrinus 6715 to synthesize water-insoluble glucan. moreover, it not only significantly inhibited the synthesis of water-insoluble glucan from sucrose, but also the sucrose-dependent adherence of these growing cells the glass surfaces. in the in ... | 1997 | 9438982 |
| dental caries and related factors in 88- and 92-year-olds. cross-sectional and longitudinal comparisons. | our aim was to compare two groups of 88- and 92-year-olds (n = 92 and n = 40), respectively, with regard to teeth, caries, and salivary and microbial conditions. oral variables were analyzed in relation to functional capacity and use of cardiovascular agents and psychoactive drugs. untreated root caries, plaque score, and counts of lactobacilli increased between the ages of 88 and 92 years (p < 0.01). nine of the 24 longitudinally followed up subjects had lost 1-5 teeth over 4 years, and 17 subj ... | 1997 | 9370025 |
| immunoglobulin a reaction to oral streptococci in saliva of subjects with different combinations of caries and levels of mutans streptococci. | the aim of this study, performed in bangkok, was to study whether a particular salivary immunoglobulin a (iga) antibody profile against mutans streptococci could be related to the absence or presence of caries. a group of 12-year-old individuals representing various combinations of mutans streptococci levels and caries experience was selected. whole saliva stimulated by paraffin-chewing was collected, and the children were investigated for decayed, missing and filled surfaces (dmfs) and teeth (d ... | 1997 | 9467389 |
| cariogenic [correction of carcinogenic] potential of a typical cassava flour from the amazonian region of brazil. | the purpose of this study was to compare the cariogenic potential of a typical cassava flour (cf) with sucrose and starch, using a severe cariogenic challenge model in rats. thirty wistar female pups with their dams (mutans streptococci free) were infected by streptococcus sobrinus 6715, desalivated when aged 25 days, and placed in a konig-hofer programmed feeder at age 26 days. they received 17 meals daily at hourly intervals for 21 days as follows: group (1) powdered plain sucrose and sterile ... | 1997 | 9495154 |
| effect of antibodies on the chain length and growth of streptococcus sobrinus. | passive immunization has been suggested as a method to prevent colonization of teeth by mutans streptococci. however, the mechanism of action of antibodies, both polyclonal and monoclonal, is not clear. in this study we investigated the effect of polyclonal antibodies (pabs) and a monoclonal antibody (omvu10) on the chain length and growth of streptococcus sobrinus. during growth in broth s. sobrinus formed significantly longer chains in the presence of pabs in comparison to pre-immune serum (p ... | 1997 | 8955992 |
| mutans streptococci caries and chlorhexidine. | mutans streptococci, particularly streptococcus mutans and streptococcus sobrinus, can be shown to be highly associated with caries in humans. together with lactobacillus spp., they are regarded as significant odontopathogens. because of their association with dental disease, an evaluation of the numbers of mutans streptococci organisms in plaque and saliva may aid in the diagnosis of caries activity. in conjunction with this concept, control and prevention of caries has been sought by reducing ... | 1996 | 8908872 |
| the inhibitory action of fatty acids on oral bacteria. | saturated and unsaturated fatty acids and fatty acid derivatives were examined for their growth-inhibitory effects towards three selected oral bacteria: porphyromonas gingivalis, selenomonas artemidis, and streptococcus sobrinus. of the 45 compounds surveyed, only one, myristoleic acid, was inhibitory towards s. artemidis at a concentration < 100 micrograms/ml. cis-hexadecenoic and cis-octadecenoic acids were generally inhibitory towards p. gingivalis and s. sobrinus, but there was no correlatio ... | 1996 | 9028262 |
| the establishment of a community of oral bacteria that controls the growth of candida albicans in a chemostat. | the purpose of this study was to establish and identify a community of oral bacteria that controls the growth of candida albicans in the chemostat. the chemostat was operated under glucose-limiting conditions at a dilution rate of 0.05 h-1 and inoculated with a yeast-free suspension of a tongue scraping. after a steady state had been reached, it was inoculated with c. albicans to establish the yeast and determine whether its growth could be contained. the steady-state community comprised the spe ... | 1996 | 8941776 |
| incorporation of caseinoglycomacropeptide and caseinophosphopeptide into the salivary pellicle inhibits adherence of mutans streptococci. | the protective effects of milk and milk products against dental caries have been demonstrated in many animal studies. we have shown that this effect was mediated by micellar casein or caseinopeptide derivatives. a reduction in the streptococcus sobrinus population in the oral microbiota of animals fed diets supplemented with these milk components was consistently observed. a possible explanation for these findings is that milk components are incorporated into the salivary pellicle, thereby reduc ... | 1996 | 8955673 |
| in vitro evaluation of antibacterial effects of photo-cured glass ionomer liners and dentin bonding agents during setting. | two dentin bonding agents (optibond and syntac), an enamel bonding agent (heliobond), and two photo-cured glass ionomer cements (vitremer and variglass vlc) and their inhibitory effects on bacterial growth during setting were examined. cultures of eight bacterial species were used to test these materials, except for vitremer glass ionomer cement, which was tested against only five species. the photo-cured glass ionomer cements and the syntac dentin bonding system with glutaraldehyde demonstrated ... | 1996 | 8933437 |
| kinetic properties of glucosyltransferase adsorbed onto saliva-coated hydroxyapatite. | results from previous studies have shown that several properties of glucosyltransferase (gtf) adsorbed onto saliva-coated hydroxyapatite beads differ from those of gtf in solution. for example: thermostability, ph-activity dependency, sensitivity to inhibitors. the aim of this study was to compare the kinetics of the adsorbed gtf with its kinetic properties in solution. hydroxyapatite beads were coated with human parotid saliva (sha). following washes, cell-free gtf enzyme from streptococcus sob ... | 1996 | 8879428 |
| inhibitory effects of funoran on the adherence and colonization of mutans streptococci. | funoran, a sulfated polysaccharide extracted from the seaweed gloiopeltis furcata strongly inhibited the absorption of mutans streptococci to saliva-coated hydroxyapatite (s-ha), but enhanced that of streptococcus sanguis atcc 10556 and streptococcus oralis atcc 10557. furthermore, funoran had a strong desorption activity against mutans streptococci preadsorbed to s-ha. in the presence of sucrose, the absorption of cells of streptococcus sobrinus b13, streptococcus mutans ingbritt, and s. mutans ... | 1996 | 8833135 |
| anti-adhesins of streptococcus sobrinus. | 1996 | 8895800 | |
| defining antibody targets in streptococcus oralis infection. | immunoblotting of sera from 12 neutropenic patients with streptococcus oralis septicemia and 18 patients with endocarditis due to viridans group streptococci revealed immunodominant s. oralis antigens at 85 and 180 kda. the former cross-reacted with a mouse monoclonal antibody to hsp90. the latter was identified by sequencing positive clones obtained by screening a genomic expression library of s. oralis with pooled sera from patients who had been infected with s. oralis. antibody eluted from on ... | 1996 | 8613367 |
| the inhibiting effect of aqueous azadirachta indica (neem) extract upon bacterial properties influencing in vitro plaque formation. | the purpose of this investigation was to examine the inhibitory effects of aqueous extracts derived from the bark-containing sticks (neem stick) of azadirachta indica upon bacterial aggregation, growth, adhesion to hydroxyapatite, and production of insoluble glucan, which may affect in vitro plaque formation. neem stick extracts were screened for minimal bacterial growth inhibition (mic) against a panel of streptococci by means of a broth dilution assay. initial bacterial attachment was quantifi ... | 1996 | 8655780 |
| characterization of a p1-deficient strain of streptococcus mutans that expresses the spaa protein of streptococcus sobrinus. | the streptococcus sobrinus spaa protein and the streptococcus mutans p1 protein share 66% sequence homology at the amino acid level. to determine if the spaa protein can be expressed in s. mutans and functionally replace the p1 protein, the spaa gene of s. sobrinus 6715 was isolated from plasmid px1303 and inserted into the escherichia coli-streptococcus shuttle vector pva838. the resulting plasmid px1600 was transformed into the p1-deficient strain s. mutans 834 that has defects in saliva-media ... | 1996 | 8751913 |
| effects of copper, iron and fluoride co-crystallized with sugar on caries development and acid formation in deslivated rats. | the purpose was to explore the effects of combinations of copper, iron and fluoride (cu, fe and f) incorporated in sucrose by co-crystallization on caries development in the deslivated rat model and to examine acid formation by bacteria in the rat mouth. ninety-six sprague-dawley rats were infected with streptococcus sobrinus 6715 and desalivated when aged 26 days. eight groups were placed in a könig-höfer programmed feeder and received 17 meals daily at hourly intervals, and essential nutrition ... | 1996 | 9068864 |
| antibacterial effect of chlorhexidine on bacteria adsorbed onto experimental dental plaque. | the most common method used to examine the antibacterial effect of antiplaque agents is the minimal inhibitory concentration (mic) method, which is tested on bacteria in suspensions. examining the antibacterial effect on bacteria adsorbed onto dental surfaces models is not as popular, although it is clear that such models reflect the conditions in the oral cavity far more accurately than the conventional mic method. the antibacterial effect of chlorhexidine (chx) on bacteria adsorbed onto experi ... | 1996 | 9078445 |
| multiple glucan-binding proteins of streptococcus sobrinus. | several proteins from culture supernatants of streptococcus sobrinus were able to bind avidly to sephadex g-75. the proteins could be partially eluted from the sephadex by low-molecular-weight alpha-1,6 glucan or fully eluted by 4 m guanidine hydrochloride. elution profiles were complex, yielding proteins of 16, 45, 58 to 60, 90, 135, and 145 kda, showing that the wild-type strain possessed multiple glucan-binding proteins. two mutants of streptococcus sobrinus incapable of aggregation by high-m ... | 1996 | 8626283 |
| cariogenicity depends more on diet than the prevailing mutans streptococcal species. | this review aims to compare the occurrence and distribution of mutans streptococci in africa, europe, and north america and in addition will try to offer explanations for existing relationships among salivary mutans streptococci counts, dietary patterns, and dental caries. the literature reveals that salivary mutans streptococci counts in child populations of the three continents are comparable. the distribution of mutans streptococci species, with a predominance of s. mutans followed by s. sobr ... | 1996 | 8655757 |
| initial ph as a determining factor of glucose consumption and lactic and acetic acid production in oral streptococci. | lactic and acetic acid production was evaluated from six strains of oral streptococci, viz streptococcus gordonii, streptococcus mutans, streptococcus oralis, streptococcus salivarius, streptococcus sanguis and streptococcus sobrinus cultured in the presence of 1, 5, 10 mm glucose and without glucose, at initial ph values of 5, 5.5, 6 and 7. s. sobrinus and s. salivarius caused the greatest decreases in ph. at ph values of 5 and 5.5, lactic acid and acetic acid production in the species tested w ... | 1996 | 9082145 |
| effect of low-dose glucocorticoid treatment on dentin formation and dentinal caries in rats. | the effect of a low dose of glucocorticoids on dentin formation and progression of dental caries was studied in young rats. the animals were inoculated in the mouth with streptococcus sobrinus and fed ad libitum a high-sucrose, a high-starch, or a reference diet. the cortisone or placebo pellet was implanted subcutaneously in the back of the necks of the animals. after a 6-week experimental period the areas of dentin formation and dentinal caries were quantified planimetrically. schiff's stainin ... | 1996 | 8923921 |