Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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college alcohol belief and alcohol use: testing moderations by cultural orientations and ethnicity. | alcohol is considered an integral part of the college life; students who hold stronger college alcohol beliefs typically consume more alcohol and experience more negative drinking consequences. asian americans are increasingly at risk for hazardous alcohol use, yet little research has focused on whether college alcohol beliefs are conceptualized similarly in this group and whether individuals' cultural orientations moderate the relations between college alcohol beliefs and alcohol involvement. a ... | 2020 | 31343217 |
clinical and economic impact of clinical pharmacist interventions regarding antimicrobials on critically ill patients. | incorporating in the intensive care unit (icu) a clinical pharmacist who performs interventions on antimicrobials may be cost-effective. | 2020 | 31327737 |
[economic evaluation of pneumococcal vaccination in adults aged over 65 years in castilla y león (spain)]. | the burden of disease due to pneumonia in older adults has a major impact on health systems. the aim of this study is to carry out an economic evaluation of the vaccination strategy against streptococcus pneumoniae using the 13-valent pneumococcal conjugate vaccine. | 2020 | 31307781 |
a cross-cultural exploration on the psychological aspects of skin color aesthetics: implications for sun-related behavior. | sociocultural values toward skin color manifest in daily behaviors, such as sun-seeking behaviors in euro-american culture and sun-protective behaviors in chinese culture. however, little research has investigated how attitudes toward skin color affect sun-related behaviors in the face of conflicting cultural values. this study explores how sociocultural contexts shape attitudes toward skin color and sun-related behaviors in three groups of genetically chinese women, located on a spectrum from p ... | 2020 | 31120122 |
characteristics of potential concussive events in three elite football tournaments. | identify patterns in the nature and characteristics of potential concussive events (pces) in football. | 2020 | 31331934 |
the development of the gluten free healthy food basket in cyprus. is it affordable among low-income adults diagnosed with celiac disease? | gluten free (gf) diets are not only restrictive but also costly. the main aim of this study was to evaluate the acceptability, cost and affordability of a gluten free healthy food basket (gfhfb) and further examine whether low-income cypriots diagnosed with celiac disease (cd) experience food stress. | 2020 | 31329915 |
results of more than 11,000 scans with weightbearing ct - impact on costs, radiation exposure, and procedure time. | weightbearing ct (wbct) has been proven to more precisely measure bone position than conventional weightbearing radiographic series (r) and conventional ct (ct). the purpose of this study was to assess the benefit of using wbct instead of r and/or ct as the standard imaging modality, evaluating image acquisition time, radiation dose, and cost-effectiveness. | 2020 | 31239196 |
field-testing the euro-mcd instrument: experienced outcomes of moral case deliberation. | moral case deliberation is a form of clinical ethics support to help healthcare professionals in dealing with ethically difficult situations. there is a lack of evidence about what outcomes healthcare professionals experience in daily practice after moral case deliberations. the euro-mcd instrument was developed to measure outcomes, based on the literature, a delphi panel, and content validity testing. to examine relevance of items and adequateness of domains, a field study is needed. | 2020 | 31177947 |
metacognitive octonion-valued neural networks as they relate to time series analysis. | in this paper, a metacognitive octonion-valued neural network (mc-ovnn) learning algorithm and its application to diverse time series prediction are presented. the mc-ovnn is comprised of two components: the octonion-valued neural network that represents the cognitive component and the metacognitive component that serves to self-regulate the learning algorithm. at each epoch, the metacognitive component decides if, how, and when learning occurs. the algorithm deletes unneeded samples and only st ... | 2020 | 30990445 |
clinical and economic benefits of upper airway stimulation for obstructive sleep apnea in a european setting. | upper airway stimulation (uas) is a treatment approach for patients with moderate-to-severe obstructive sleep apnea who cannot adhere to continuous positive airway pressure therapy. | 2020 | 30923287 |
societal costs of schizophrenia in denmark: a nationwide matched controlled study of patients and spouses before and after initial diagnosis. | information on welfare cost of patients with schizophrenia and spouses is limited. | 2020 | 31188445 |
spondylectomy for primary ewing lumbar sarcoma in children. | primary ewing sarcoma in the spine is very rare, and the treatment for it is multidisciplinary. there is no consensus regarding the optimal method of local control; however, en bloc resection is associated with an improvement in survival rates. the authors report a case of a 5-year-old girl who initially presented low back pain, and was diagnosed with ewing sarcoma after being submitted to imaging studies by radiography, magnetic resonance and bone biopsy. a spondylectomy was performed in accord ... | 2020 | 33093732 |
vision-related quality of life in patients treated for myopic choroidal neovascularization: a post hoc analysis of the olimpic study. | to investigate vision-related quality of life in patients referred to the italian retina services for intravitreal ranibizumab treatment for choroidal neovascularization due to pathologic myopia. | 2020 | 31169023 |
use of patient-reported outcome measures and patient-reported experience measures in renal units in australia and new zealand: a cross-sectional survey study. | patient-reported outcome measures (proms) and patient-reported experience measures (prems) are increasingly used in research to quantify how patients feel and function, and their experiences of care, however, knowledge of their utilization in routine nephrology is limited. | 2020 | 30838732 |
today's vaccination policies in italy: the national plan for vaccine prevention 2017-2019 and the law 119/2017 on the mandatory vaccinations. | the national plan for vaccine prevention 2017-2019 has expanded the vaccination offer including new vaccines, enlarging the target population and introducing for the first time in italy a life-course approach to vaccination. a "lifetime immunization schedule" is aimed to reduce the burden and the related costs of vaccine-preventable diseases through effective vaccination programs. however, to counteract the national steady downward trend in the uptake of vaccinations that caused a drop of the vac ... | 2020 | 30994164 |
[expenditures of the german statutory health insurance for health promotion and disease prevention 2012-2017: positive effects due to the disease prevention law?] | the german prevention act aims to strengthen health promotion and disease prevention. the law makes changes to the so-called "§20 measures". target values were newly given for the expenditures of the health insurance funds in this area. the objective here was to examine how the prevention expenditures of the statutory health insurance developed in the period from 2012 to 2017, and whether the requirements of the prevention act were met. | 2020 | 30822817 |
epidemiology of traumatic brain injury in oltenia region: a retrospective study. | traumatic brain injury (tbi) represents a common cause of presentation in the emergency room and is considered a major health problem all over the world. our study objective was to provide a regional perspective from a county hospital regarding epidemiologic aspect of tbi in a single year and to compare it with existing studies. 592 patients fulfilled the inclusions criteria and their characteristics were noted. we observed that the highest rate of tbi was among older people with an age over >60 ... | 2020 | 30746166 |
incidence and outcome of peri-procedural cardiogenic shock: results from the international euro heart survey pci registry. | there is a large body of literature on acute myocardial infarction complicated by cardiogenic shock. however, very little is known about patients who are initially haemodynamically stable and develop cardiogenic shock during percutaneous coronary intervention. | 2020 | 30618264 |
effects of polymorphisms in apob, apoe, hsd11β1, plin4, and adipoq genes on lipid profile and anthropometric variables related to obesity in children and adolescents. | genes can influence lipid profile and anthropometric variables related to obesity. the present study aimed to verify if variants of the apoe, apob, adipoq, hsd11β1, and plin4 genes are associated with lipid levels or anthropometric variables in a sample comprised of 393 euro-brazilian children and adolescents. dna was genotyped by taqman allelic discrimination assay. the ε4 and ε2 alleles of the apoe gene were associated respectively with lower high-density lipoprotein cholesterol (hdl-c) and lo ... | 2020 | 30507998 |
probabilistic cost-utility analysis and expected value of perfect information for the oncotype multigenic test: a discrete event simulation model. | to carry out a cost-utility analysis of the application of the oncotype genomic test to inform the decision to use or not to use chemotherapy in the basque country (spain). | 2020 | 30442434 |
comparative analysis of the sokal, euro and european treatment and outcome study score in prognostication of indian chronic myeloid leukemia-chronic phase patients on imatinib. | the ultimate goal for cml management is risk stratification of the patients to design the appropriate treatment approach. the sokal, euro and eutos risk scores were established to prognosticate the patients on therapy. | 2020 | 30430096 |
the symptom network structure of depressive symptoms in late-life: results from a european population study. | the network theory conceptualizes mental disorders as complex networks of symptoms influencing each other by creating feedback loops, leading to a self-sustained syndromic constellation. symptoms central to the network have the greatest impact in sustaining the rest of symptoms. this analysis focused on the network structure of depressive symptoms in late-life because of their distinct etiologic factors, clinical presentation, and outcomes. we analyzed cross-sectional data from wave 2 of the 19 ... | 2020 | 30171210 |
the impact of dependency act benefits on employment. | to assess the amount of employment generated from the effective development of the dependency act in 2012, by evaluating the number of jobs depending on whether in-kind services or cash benefits were applied. | 2020 | 30146179 |
the first euro-asian congress of pharmacoepidemiology: a real instance for a multidisciplinary approach. | 2020 | 29755992 | |
real-world use of biological drugs in patients with psoriasis/psoriatic arthritis: a retrospective, population-based study of years 2010-2014 from southern italy. | biological drugs, such as infliximab, etanercept, adalimumab, ustekinumab, golimumab and certolizumab are third-line therapy for psoriasis (pso) and psoriatic arthritis (psa), but they may be used at earlier stage in severe forms. this study investigated the pattern of use and costs of biological drugs for pso/psa in a large population from southern italy during the years 2010-2014. | 2020 | 29582617 |
[percutaneous coronary intervention and minimally invasive aortic valve replacement for patients with aortic valve disease and coronary artery disease]. | to report the resultsof hybrid approach combining percutaneouscoronary intervention (pci)and minimally invasive aortic valvereplacement through right anteriorminithoracotomy (rt-avr) for patientswith aortic valve disease andcoronary artery disease. | 2020 | 29694767 |
patterns of trauma and violence in 19th-century-born african american and euro-american females. | trauma and violence has been a topic of interest to biological anthropologists. this study examined the presence of trauma, including interpersonal violence, in a sample (n=256) of african american and euro-american females of low socioeconomic status, born from 1800 to 1877, from the terry collection. individuals were statistically analyzed according to ancestry (african american and euro-american), birth (antebellum, civil war, reconstruction), and birth status (enslaved black, pre-reconstruct ... | 2019 | 29539383 |
irritable bowel symptoms, use of healthcare, costs, sickness and disability pension benefits: a long-term population-based study. | objectives: irritable bowel syndrome (ibs) is associated with increased healthcare use and work absenteeism. we aimed to investigate long-term use of healthcare services and social benefits across ibs symptom groups. additionally, we estimated excess healthcare costs. methods: a longitudinal population-based study comprising two 5-year follow-up studies: the danish part of the multinational monitoring of trends and determinants in cardiovascular disease (dan-monica) 1 (1982-1987) and inter99 (19 ... | 2019 | 29762084 |
[satellite center of human milk: analysis of cost reduction]. | donor milk is the second best alternative for a newborn after the mother's own milk, especially when the baby is a premature or a sick child since this milk has the advantage of protecting against necrotizing enterocolitis. there are currently 13 milk banks in spain, however this is not sufficient to supply all spanish neonatal units with donor milk. in order to bring donor milk to the babies in neonatal unit of the regional university hospital of malaga, a satellite centre (cs) was created in 2 ... | 2019 | 29454738 |
changes in quality of life in patients with postmenopausal osteoporosis receiving weekly bisphosphonate treatment: a 2-year multicenter study in japan. | we investigated changes in quality of life (qol), including pain, in japanese women aged ≥ 55 years who were diagnosed as having osteoporosis at 265 centers across japan and treated continuously with once-weekly bisphosphonates for 24 months. in 2650 evaluable patients, a significant improvement in qol was observed from 3 months after enrollment onward and maintained throughout the 2-year observation period. a significant improvement in scores was observed for all domains of the euro qol 5 dimen ... | 2019 | 29523963 |
medium and long-term prognosis of transcatheter aortic valve implantation from the perspective of left ventricular diastolic function. | the effects of left ventricular (lv) diastolic function are well known in cardiac surgery, but unclear in transcatheter aortic valve implantation (tavi). the objective of this study was to exam- ine the association of preoperative lv diastolic function with medium to long-term outcomes of tavi. | 2019 | 29570210 |
health related quality of life and its associated factors among community-dwelling older people in sri lanka: a cross-sectional study. | population ageing has become a public health issue as it is associated with increased morbidity, institutionalization and death. these may directly affect health-related quality of life (hrqol) of older people. | 2019 | 29567617 |
childhood socioeconomic status and late-adulthood mental health: results from the survey on health, ageing and retirement in europe. | a growing literature acknowledges the association between childhood socioeconomic status (ses) and health in late adulthood (i.e., 50+). less, however, is known about the association with mental health outcomes, such as depression. we use the survey on health, ageing, and retirement in europe (share) to analyze overall and gender-specific associations between childhood ses and late-adulthood depression. | 2019 | 29566242 |
behavioral economic purchase tasks to estimate demand for novel nicotine/tobacco products and prospectively predict future use: evidence from the netherlands. | the demand for alternative nicotine/tobacco products is not well established. this paper uses a behavioral economic approach to test whether smokers have differential demand for conventional factory-made, electronic, and very low nicotine content cigarettes (fmcs/ecs/vlncs) and uses the prospective cohort design to test the predictive validity of demand indices on subsequent use of commercially available fmcs and ecs. | 2019 | 29547973 |
'ayn mika: traumatic experience, social invisibility, and emotional distress of sub-saharan women with precarious status in morocco. | morocco has become a permanent transit country for tens of thousands of sub-saharan migrants heading to europe. many of these migrants are women who have a precarious legal status and can no longer reach europe, whose borders have been considerably securitized since september 11, 2001. they also have no wish to risk their lives again returning south across the sahara desert. this paper discusses the results of an exploratory research project conducted in morocco on the relationships between the ... | 2019 | 29516775 |
evaluation of hospital length of stay and revenues as a function of admission mode, clinical pathways including observation unit stay and hospitalization characteristics. | hospital length of stay (days) and revenues per day (euros) could be different depending on admission mode. to determine the impact of admission mode as a function of clinical pathway, we conducted the present study. data sources: we included 159,206 admissions to three academic hospitals during a four-year period. data were obtained from the electronic system of the hospital trust. | 2019 | 29701496 |
concurrent use of benzodiazepine by heroin users-what are the prevalence and the risks associated with this pattern of use? | polydrug use involving heroin and benzodiazepines is common. the potential risk of additive pharmacological effects may be associated with poorer outcomes in patients who use benzodiazepines together with heroin. the aim of this study was to determine the clinical picture of patients presenting to the emergency department following acute drug toxicity involving heroin and benzodiazepines. | 2019 | 30066312 |
economic impact of severe asthma in spain: multicentre observational longitudinal study. | objective: estimate the economic impact of severe asthma from the spanish social perspective through the estimation of the associated annual direct and indirect costs. methods: observational, longitudinal, retrospective study carried out in 20 spanish secondary settings (pulmonology and allergy services) among patients aged ≥18, diagnosed with severe asthma according to european respiratory society/american thoracic society consensus and who have not experienced an exacerbation in the previous 2 ... | 2019 | 30003827 |
improving breakfast patterns of portuguese children-an evaluation of ready-to-eat cereals according to the european nutrient profile model. | ready-to-eat cereal (rtec) breakfasts have been increasing in portugal, among children. eat mediterranean (em), a portuguese comprehensive community-based intervention, proposed to improve breakfast patterns of children and adolescents and to evaluate the healthiness of rtec according to who/europe nutrient profile model (euro-np). | 2019 | 29973677 |
[new possibilities of pharmacotherapy of epilepsy: eslicarbazepine acetate in treatment of focal epilepsy]. | the article provides an analysis of the latest antiepileptic drug eslicarbazepine acetate (esl) for the treatment of focal epilepsy in adults as monotherapy and adjunctive therapy. pharmacokinetics, pharmacodynamics, drug-drug interactions, indications and dosage regimen are described. the authors present the latest data on the efficacy, tolerability and safety of esl including an exploratory pooled analysis of data from 14 european clinical practice studies (euro-esli) as well as their own obse ... | 2019 | 29863708 |
the infrastructure of telecare: implications for nursing tasks and the nurse-doctor relationship. | telecare can offer a unique experience of trust in patient-nurse relationships, embracing new standards for professional discretion among nurses, but also reflects an increasingly complicated relationship between nurses and doctors. the study uses ethnographic methodology in relation to a large 5 million euro project at four hospitals caring for 120 patients with copd. twenty screen-mediated conferences were observed and two workshops, centring on nurses' photo elucidation of the practice of tel ... | 2019 | 30076621 |
association between alcohol exposure and the risk of amyotrophic lateral sclerosis in the euro-motor study. | several studies focused on the association between alcohol consumption and amyotrophic lateral sclerosis (als), although with inconsistent findings. antioxidants may play a role since lyophilised red wine was found to prolong sod1 mice lifespan. the aim of this international population-based case-control study performed in ireland, the netherlands and italy was to assess the role of alcohol, and red wine in particular, in developing als. | 2019 | 30076269 |
the economic burden of disease of epithelial ovarian cancer in spain: the ovarcost study. | to assess the economic burden of epithelial ovarian cancer (eoc) in incident patients and the burden by disease stage in spain. | 2019 | 29922900 |
analysis of the costs and cost-effectiveness of the guidelines recommended by the 2018 gesida/spanish national aids plan for initial antiretroviral therapy in hiv-infected adults. | the gesida/national aids plan expert panel recommended preferred regimens (pr), alternative regimens (ar) and other regimens (or) for antiretroviral treatment (art) as initial therapy in hiv-infected patients for 2018. the objective of this study was to evaluate the costs and the efficiency of initiating treatment with pr and ar. | 2019 | 29884455 |
lumbar spinal stenosis: comparison of surgical practice variation and clinical outcome in three national spine registries. | decompression surgery for lumbar spinal stenosis (lss) is the most common spinal procedure in the elderly. to avoid persisting low back pain, adding arthrodesis has been recommended, especially if there is a coexisting degenerative spondylolisthesis. however, this strategy remains controversial, resulting in practice-based variation. | 2019 | 29792994 |
benefits and costs of home pedometer assisted physical activity in patients with copd. a preliminary randomized controlled trial. | there are barriers to providing pulmonary rehabilitation for chronic obstructive pulmonary disease (copd) such as the high number of patients, difficult access to health facilities and high costs of programs. pedometers can monitor and improve physical activity (pa). the aim of this study was to evaluate benefits and costs of home pedometer assisted pa, as compared to a standard outpatient supervised exercise training program in patients with copd. | 2019 | 30008335 |
[health surveillance programme for workers with past asbestos exposure in tuscany region (central italy)]. | asbestos-related diseases are characterized by a long latency time since exposure. this accounts for a health surveillance programme addressed to asbestos workers to be performed for decades after the cessation of occupational exposure. we describe the health surveillance programme for former asbestos-exposed workers in tuscany region (central italy), with particular attention to organization and related critical issues. the deliberation of the regional administration of tuscany (no. 396/2016) s ... | 2019 | 29774715 |
the effect of neuropathic pain symptoms on remission in patients with early rheumatoid arthritis. | the presence of neuropatic pain (nep) is common in subjects with established rheumatoid arthritis (ra), and it can influence the disease remission. these aspects have not been investigated in patients with early rheumatoid arthritis (era). | 2019 | 30081788 |
assessment of clinical parameters of the polytraumatized patient as predictors of hospital expenditure and of its distribution. | traumatic pathology continues to represent an important socio-health problem. the aim of the study was to assess the clinical predictors of total expenditure, as well as to analyze which components of the cost are modified with each clinical parameter of the polytraumatized patient. | 2019 | 30139578 |
molecular epidemio-logy of tuberculosis in the capital of prague in 2013 and 2014. | phylogenetic analysis of mycobacterium tuberculosis strains by the miru-vntr method and their assignment to lineages and sublineages. | 2019 | 30126282 |
impact of 13valent vaccine for prevention of pneumococcal diseases in children and adults at risk: possible scenarios in campania region. | pneumonias are the most frequent infectious diseases, characterized by a high prevalence especially among children and adults at risk. the socio-economic impact caused by streptococcus pneumoniae is evaluated in terms of morbidity, death rate and hospitalizations. | 2019 | 30124160 |
the impact of depressive symptoms on exit from paid employment in europe: a longitudinal study with 4 years follow-up. | mental health problems are a risk factor for loss of paid employment. this study investigates (i) the relation between depressive symptoms and different involuntary pathways of labour force exit and (ii) explores gender and geographical differences in this relation. | 2019 | 30052918 |
healthcare costs and outcomes in adult patients with juvenile idiopathic arthritis: a population-based study. | evidence of the economic burden and long-term outcomes of juvenile idiopathic arthritis (jia) remains scarce. our aim was to explore healthcare costs and long-term outcomes in adult patients with jia. | 2019 | 30070935 |
exploring different strategies of assessing the economic impact of multiple diabetes-associated complications and their interactions: a large claims-based study in germany. | in the context of an aging population with increasing diabetes prevalence, people are living longer with diabetes, which leads to increased multimorbidity and economic burden. | 2019 | 30167918 |
presentations to the emergency department with non-medical use of benzodiazepines and z-drugs: profiling and relation to sales data. | non-medical use of benzodiazepines and z-drugs is common; however, there is limited information available on the extent of harm related to this in europe, as well as the relationship between misuse and availability. | 2019 | 30244371 |
laparoscopic sleeve gastrectomy learning curve: clinical and economical impact. | the results in the literature regarding the learning curve (lc) of laparoscopic sleeve gastrectomy (lsg) are scarce and non-definitive. the purpose of the study was to evaluate the correlation between the lsg learning curve and intraoperative parameter variation, postoperative morbidity, weight loss results, and economic impact. | 2019 | 30194588 |
recovery of quality of life after laparoscopic myomectomy. | it is commonly thought that laparoscopic surgery leads to faster postoperative recovery for its low invasiveness. we evaluated postoperative quality of life (qol) after laparoscopic myomectomy (lm) by using the euro-qol 5 dimension (eq-5d) score and analyzed its relationship to surgical factors. | 2019 | 30255650 |
eslicarbazepine acetate as monotherapy in clinical practice: outcomes from euro-esli. | to assess the effectiveness and safety/tolerability of eslicarbazepine acetate (esl) monotherapy in clinical practice in europe. | 2019 | 30176048 |
use of whole-genome sequencing to predict mycobacterium tuberculosis drug resistance in indonesia. | whole-genome sequencing (wgs) is rarely used for drug resistance testing of mycobacterium tuberculosis in high-endemic settings. here we present the first study from indonesia, which has the third highest tuberculosis (tb) burden worldwide, with <50% of drug-resistant cases currently detected. | 2019 | 30172045 |
economic evaluation of a person-centred care intervention in head and neck oncology: results from a randomized controlled trial. | head and neck cancer and its treatment deteriorate quality of life, but symptoms improve with person-centred care. we examined the cost-effectiveness of a person-centred care intervention versus standard medical care. | 2019 | 30171334 |
course of depressive symptoms and associated factors in people aged 65+ in europe: a two-year follow-up. | the epidemiology of depressive disorders presents notable differences among european countries. the objectives of the study are to determine the prevalence, incidence, persistence and remission rates of depressive symptoms and to identify risk factors and differences between four european regions. | 2019 | 30428444 |
patterns of practice and pharmacoeconomic analysis of the management of patients with metastatic renal cell carcinoma (mrcc) in greece--the crisis study. a retrospective analysis by the hellenic genitourinary cancer group (hgucg). | background:metastatic rcc (mrcc) treatment has been revolutionized with 11 approved targeted agents. we report patterns of practice, outcomes and pharmacoeconomic analyses after the introduction of targeted therapy. patients and methods: crisis was a retrospective multicenter study of mrccpatients who received targeted therapy . results were related to the start of 1st-line therapy, with a cut off at 1 january 2011 in order to depict the impact of increased availability of effective options. res ... | 2019 | 30417707 |
life after an autism spectrum disorder diagnosis: a comparison of stress and coping profiles of african american and euro-american caregivers. | the purpose of the present study was to understand how caregiver stress and coping behaviors impact african american and euro-american families differently when caring for a child with autism. this study used discriminate function analysis to contrast the stress and coping profiles of euro-american caregivers who are more acculturated with the majority culture with african american caregivers who ascribe to more traditional values. a sample of 103 families was recruited (52 euro-american, 51 afr ... | 2019 | 30392026 |
non-typhi, non-paratyphi salmonella-related hospitalisations in spain: trends, clinical aspects, risk factors for worse prognosis and hospital costs. | this study reviews non-typhoid salmonella (nts)-related hospitalisations at national level in spain between 2010 and 2015. nts hospitalisations were obtained from the national registry of hospitalisations. a descriptive analysis of the hospitalisations was performed, including hospitalisation rates (hr) and case-fatality rates (cfr%) calculation. for those with nts as main diagnosis logistic regression were used to estimate the relationship between the different factors and death outcome. 21,660 ... | 2019 | 30456436 |
responses of a resistive soot sensor to different mono-disperse soot aerosols. | since 2011, the euro 5b european standard limits the particle number (pn) emissions in addition to the particulate mass (pm) emissions. new thermal engine equipped vehicles also have to auto-diagnose their own particulate filter (diesel particulate filter or gasoil particulate filter) using on-board diagnostic (obd) sensors. accumulative resistive soot sensors seem to be good candidates for pm measurements. the aim of this study is to bring more comprehension about soot microstructures construct ... | 2019 | 30744083 |
a home-based tele-rehabilitation protocol for patients with hip fracture called @ctivehip. | home-based tele-rehabilitation programs are under development and may be a future option for some patients. the objectives of this non-randomized clinical trial are to design a home-based multidisciplinary tele-rehabilitation protocol for patients with hip fracture, and to compare this protocol versus the home-based usual outpatient rehabilitation protocol. seventy patients treated for an acute hip fracture, aged 65 years or older, with a high pre-fracture functional level (functional independen ... | 2019 | 30444530 |
herd immunity and primary immune deficiencies. | this letter addresses the issues adjoining the article by bernadou et al. measles outbreak linked to insufficient vaccination coverage in nouvelle-aquitaine region, france, october 2017 to july 2018. euro surveill. 2018;23(30):pii = 1800373. https://doi.org/10.2807/1560-7917.es.2018.23.30.1800373. the decreased vaccination rates against measles are decreasing herd immunity to this agent, posing a risk for patients with patient immune deficiency as the measles antibody titre decreases in products ... | 2019 | 30497836 |
the rich are different: unravelling the perceived and self-reported personality profiles of high-net-worth individuals. | beyond money and possessions, how are the rich different from the general population? drawing on a unique sample of high-net-worth individuals from germany (≥1 million euro in financial assets; n = 130), nationally representative data (n = 22,981), and an additional online panel (n = 690), we provide the first direct investigation of the stereotypically perceived and self-reported personality profiles of high-net-worth individuals. investigating the broad personality traits of the big five and t ... | 2019 | 30466138 |
enhanced recovery protocols in colonic surgery: retrospective cohort analysis of economic impact from an institutional point of view. | despite increasing evidence supporting the beneficial effects of enhanced recovery protocols (erps), their accurate economic impact on institutions remains lacking. the aim of this study was to analyze erp economic impact in a french center in order to further encourage implementation. | 2019 | 30460474 |
exploring multi-use potentials in the euro-mediterranean sea space. | european seas are experiencing rapid development. the anthropogenic demand for marine resources and space exerts the need for novel concepts for sustainable resource exploitation and smart space allocation. multi-use (mu) is an emerging concept to overcome spatial claims and support blue growth, however its actual potentials and current status of implementation in different sea basins is to a large extent unexplored. an analytical framework using a mixed method approach is proposed for the ident ... | 2019 | 30414590 |
the burden of cancer in spain. | cancer imposes a huge financial burden in all developed countries. this study estimates the burden of cancer in spain in 2015. | 2019 | 30414063 |
from sameness to difference: swedish somalis' post-migration perceptions of the circumcision of girls and boys. | in every society where non-therapeutic female circumcision (fc) occurs, so too does non-therapeutic male circumcision (mc). in the past few decades, the norm in euro-american societies has been to distinguish between the practices: fc is banned, while mc is condoned or encouraged. we explored somalis' post-migration perceptions of fc and mc, while considering that they once lived in a society where both practices were widely accepted and now live in a society where there is a legal ban on fc alo ... | 2019 | 30411652 |
vastly different exercise programs similarly improve parkinsonian symptoms: a randomized clinical trial. | to directly compare the effects of agility exergaming (exe) and stationary cycling (cyc) exercise training on parkinson's disease (pd) patients' mobility and clinical symptoms. | 2019 | 30368495 |
cost-of-illness of melanoma in europe - a systematic review of the published literature. | malignant melanoma accounts for the vast majority of skin cancer deaths. primary prevention is used to increase knowledge about skin cancer and set incentives for a change in behaviour, which leads to a decrease in cases. primary prevention may be cost-effective or even cost saving. cost-of-illness (coi) studies provide information on such potential savings. the purpose of this study is to give an overview on coi studies in european countries and to compare the coi in total and by cost categorie ... | 2019 | 30408246 |
therapeutic and economic effects of multimodal back exercise: a controlled multicentre study. | to compare the cost-effectiveness of a multimodal back exercise programme for non-specific back pain with that of standard treatment. medical costs were measured in euros (eur) and effectiveness was measured using graded chronic pain status (gcps). a controlled multicentre study (39 sites) with a 6-month intervention phase and follow-up at 6, 12 and 18 months. the study included 1,829 participants in an intervention group and 495 individuals in a control group. the multimodal back exercise progr ... | 2019 | 30406268 |
a cost-effectiveness threshold based on the marginal returns of cardiovascular hospital spending. | traditionally, threshold levels of cost-effectiveness have been derived from willingness-to-pay studies, indicating the consumption value of health (v-thresholds). however, it has been argued that v-thresholds need to be supplemented by so-called k-thresholds, which are based on the marginal returns to health care. the objective of this research is to estimate a k-threshold based on the marginal returns to cardiovascular disease (cvd) hospital care in the netherlands. to estimate a k-threshold f ... | 2019 | 30273967 |
mode of presentation and mortality amongst patients hospitalized with heart failure? a report from the first euro heart failure survey. | heart failure is heterogeneous in aetiology, pathophysiology, and presentation. despite this diversity, clinical trials of patients hospitalized for hf deal with this problem as a single entity, which may be one reason for repeated failures. | 2019 | 30361818 |
beliefs about etiology and treatment of mental illness among korean presbyterian pastors. | this descriptive study explored pastors' beliefs about etiology and treatment of mental illness. surveys were completed by mail by 202 korean and euro-american presbyterian clergy. nearly one-third of korean pastors viewed bad parenting and demon possession as very important causes of mental illness, in contrast to the more than two-thirds of euro-american pastors who viewed genetics and chemical imbalances as the most important causes. compared with their euro-american counterparts, korean past ... | 2019 | 30341709 |
choice of septal reduction therapies and alcohol septal ablation. | in patients with resting or provoked gradients and symptoms refractory to optimal medical therapy, alcohol septal ablation or surgical septal myectomy may be considered. given the overall comparable outcomes after ablation and myectomy, there is, for many patients, equipoise between the two procedures. septal ablation is performed with standard angioplasty guiding catheters, guidewires, and balloon catheters. in the euro-asa registry, nyha functional class fell from 2.9 ± 0.5 to 1.6 ± 0.7 and gr ... | 2019 | 30447719 |
[effects of depressive comorbidities on revenues of somatic inpatients in the g-drg-system]. | depressive comorbidity is common with physically ill inpatients and is associated with many negative medical and economic effects (e. g., increased morbidity and mortality, increased length of stay, poorer quality of life and increased utilization of health services). the aim of this study is to clarify the question whether the additional costs caused by comorbid depressive diseases are recovered by additional g-drg-specific revenues in order to finance necessary diagnostics and therapies of thi ... | 2019 | 30326538 |
hcv elimination plan leads to significant benefits in managing liver-related diseases and hospital interventions: a regional simulation. | this article presents a 3-year budget impact simulation on the effects of a chronic hepatitis c (hcv) eradication plan in real-life costs incurred by the regional health service. | 2019 | 30321071 |
spoligotype-based population structure of mycobacterium tuberculosis in the jimma zone, southwest ethiopia. | to understand the population dynamics and propose more effective preventive strategies, defining the population structure of the circulating mycobacterium tuberculosis strains is important. | 2019 | 30318822 |
effectiveness of commercial face masks to reduce personal pm exposure. | cycling and walking are promoted as means of transportation which can contribute to the reduction of traffic pollution in urban areas. however, cyclists and pedestrians may be exposed to high concentrations of air pollutants due to their proximity to vehicle emissions. commercial face mask respirators are widely used, in both developing and developed countries, as an individual protective measure against particle pollution. however scientific data on the efficacy of face mask respirators in redu ... | 2019 | 30308844 |
effect of impaired cardiac conduction after alcohol septal ablation on clinical outcomes: insights from the euro-asa registry. | we analysed the impact of bundle branch block (bbb) and pacemaker (pm) implantation on symptoms and survival after alcohol septal ablation (asa) in patients with hypertrophic cardiomyopathy (hcm). | 2019 | 30304395 |
ultrasonographic imaging of the medial and lateral pouches in the knee: euro-musculus/usprm protocol(s) revisited. | 2019 | 30273681 | |
sex differences in health outcomes at one year following acute myocardial infarction: a report from the china patient-centered evaluative assessment of cardiac events prospective acute myocardial infarction study. | we examined sex differences in long-term health outcomes following acute myocardial infarction in china, including mortality, major adverse cardiac events and health status (symptoms, functioning, quality of life). | 2019 | 30270637 |
cost-effectiveness analysis of medical management versus conservative surgery for early tubal pregnancy. | is conservative surgery (laparoscopic salpingotomy) cost-effective, using fertility as the endpoint compared with medical management (methotrexate) in women with an early tubal pregnancy? | 2019 | 30520964 |
sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma. | sublingual allergen immunotherapy (slit) has been demonstrated to be both clinically efficacious and safe. however, in line with the current regulatory guidance from the european medicines agency, allergen immunotherapy (ait) products must demonstrate their efficacy and safety in pivotal phase iii trials for registration. | 2019 | 30508538 |
hospital production cost of transcranial direct current stimulation (tdcs) in the treatment of depression. | due to its ease of use, tolerance, and cost of acquisition, transcranial direct current stimulation (tdcs) could constitute a credible therapeutic option for non-resistant depression in primary care, when combined with drug management. this indication has yet to receive official recognition in france. the objective of this study is to evaluate the production cost of tdcs for the treatment of depression in hospitals, under realistic conditions. | 2019 | 30502122 |
3d printing: the second dawn of lab-on-valve fluidic platforms for automatic (bio)chemical assays. | in this work, inexpensive manufacturing of unibody transparent mesofluidic platforms for pressure-driven lab-on-a-valve (lov) methodologies is accomplished via rapid one-step 3d prototyping from digital models by user-friendly freeware. multichannel architecture having 800-1800 μm cross-sectional features with unconventional 3d conduit structures and integrating optical and electrochemical detection facilities is for the first time reported. user-defined flow-programming capitalizing upon softwa ... | 2019 | 30501183 |
global mental health and idioms of distress: the paradox of culture-sensitive pathologization of distress in cambodia. | efforts to provide culturally appropriate global mental health interventions have included attention to local idioms of distress. this article critically examines the potential gap between lay ethnopsychological understandings of the cambodian idiom of baksbat (broken courage) on the one hand and clinical conceptualizations of the idiom as a potential indicator of posttraumatic stress disorder. ethnographic semi-structured interviews with trauma survivors reveal resistance to current clinical tr ... | 2019 | 30515681 |
budget impact analysis of secukinumab versus adalimumab in the treatment of ankylosing spondylitis. | biologic treatments have enhanced the treatment outcomes of patients with active ankylosing spondylitis (as). until recently, tnf-alpha-inhibitors have been the only biologics approved for the treatment of active as. the objective of this study was to assess the potential financial impact of the first non-tnf-alpha biologic secukinumab (fully human il-17a-inhibitor) vs adalimumab (tnf-alpha-inhibitor) in the treatment of as in finland. | 2019 | 30474450 |
complications and technical failures are rare in knee ligament reconstruction: analyses based on 31,326 reconstructions during 10 years in denmark. | knowledge about treatment injuries (technical failures and complications) in relation to knee ligament reconstructions is sparse. our purpose was to describe treatment injuries to knee ligament reconstruction in denmark during a 10-year period and to suggest initiatives to reduce the risk for treatment injuries. | 2019 | 30467581 |
the future of healthcare has arrived: who dares take up the challenge? | according to the euro health consumer index, the dutch healthcare system is the champion of europe. yet we are living for longer, prosperity is increasing and the population is growing. if we do not continue to adjust our healthcare system to these trends, medical expenses in the netherlands will double to € 174 billion (in 2040). we are also facing job market difficulties in healthcare. we risk a shortfall of 125 thousand employees in 2022. it is therefore time to restructure healthcare. not to ... | 2019 | 30536147 |
once-weekly semaglutide versus once-daily liraglutide for the treatment of type 2 diabetes: a long-term cost-effectiveness analysis in estonia. | once-weekly semaglutide is a novel glucagon-like peptide-1 (glp-1) analogue for the treatment of type 2 diabetes that was associated with greater reductions in glycated hemoglobin (hba1c) and body mass index (bmi) versus once-daily glp-1 analogue liraglutide in a recent network meta-analysis (nma). the aim of the present study was to assess the long-term cost-effectiveness of once-weekly semaglutide 1 mg versus liraglutide 1.2 mg in estonia. | 2019 | 30535837 |
mortality in the visegrad countries from the perspective of socioeconomic inequalities. | large socioeconomic inequalities in health are still present in the central europe. the aim was to explore socioeconomic inequalities in mortality in visegrad countries-the czech republic, hungary, poland and slovakia (v4), by three different socioeconomic indicators (unemployment, risk of poverty/social exclusion, education). the study was conducted within the h2020 euro-healthy project. | 2019 | 30535783 |
polymethyl methacrylate in patient-specific implants: description of a new three-dimension technique. | polymethyl methacrylate (pmma), an easily moldable and economical synthetic resin, has been used since the 1940s. in addition, pmma has good mechanical properties and is one of the most biocompatible alloplastic materials currently available. the pmma can serve as a spacer and as a delivery vehicle for antibiotics. prior studies have indicated that no significant differences in infection rates exist between autologous and acrylic cranioplasty. although inexpensive, the free-hand cranioplasty tec ... | 2019 | 30676441 |
assessing the influence of boundary conditions, driving behavior and data analysis methods on real driving co2 and nox emissions. | the need to verify vehicle emissions in real world operation led to the implementation of real driving emissions (rde) test procedures, effective since september 2017 for new euro 6 cars following the commission regulation (eu) 2016/427, which defines the rde test conditions and data analysis methods to allow representative results. main factors addressed by the regulation include the share of driving operation, ambient temperature range, altitude and elevation difference. however, rde is still ... | 2019 | 30583183 |
non-leukemic pediatric mixed phenotype acute leukemia/lymphoma: genomic characterization and clinical outcome in a prospective trial for pediatric lymphoblastic lymphoma. | rare cases of hematological precursor neoplasms fulfill the diagnostic criteria of mixed phenotype acute leukemia (mpal), characterized by expression patterns of at least two hematopoietic lineages, for which a highly aggressive behavior was reported. we present a series of 11 pediatric non-leukemic mpal identified among 146 precursor lymphoblastic lymphomas included in the prospective trial euro-lbl 02. paraffin-embedded biopsies of 10 cases were suitable for molecular analyses using oncoscan a ... | 2019 | 30578714 |
cost-effectiveness analysis of the sapien 3 tavi valve compared with surgery in intermediate-risk patients. | transcatheter aortic valve implantation (tavi) has become the therapy of choice for treating severe aortic stenosis in patients at high-risk for surgery or where it is considered too risky to attempt. this uptake varies across geographies however, and its cost or value has frequently been cited as the reason for this. we sought to evaluate the potential cost and clinical impact of tavi in intermediate risk patients from a french collective perspective. | 2019 | 30547704 |