Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| pneumatic tube delivery system for blood samples reduces turnaround times without affecting sample quality. | in this study, blood samples from ed patients that were delivered to the laboratory by a pneumatic tube delivery system and by a human courier were compared for timeliness and quality of results. | 2006 | 16580476 |
| ozone treatment and the depletion of detectable pharmaceuticals and atrazine herbicide in drinking water sourced from the upper detroit river, ontario, canada. | the depletion and degradation of pharmacologically active compounds (phacs) and pesticides as a function of ozonation in drinking water treatment processes is not well studied. the a.h. weeks drinking water treatment plant (dwtp) serves the city of windsor, ontario canada, and incorporates ozone treatment into the production of drinking water. this dwtp also operates a real-time, scaled down pilot plant, which has two parallel streams, conventional and ozone plus conventional treatments. in this ... | 2006 | 16777173 |
| fluoride's effect on human dentin ultrasound velocity (elastic modulus) and tubule size. | despite fluoride (f) use in caries prevention, not much is known about its effects on tooth quality. this study evaluated the effect of tooth f concentration ([f]) on selected dentin structural and mechanical properties. third molars (n = 136) from toronto, which has 1 part per million (p.p.m.) water [f], montreal (0.2 p.p.m. water [f]), and fortaleza (brazil) (0.7 p.p.m. water [f]), were analyzed for [f], dental fluorosis (df) severity, ultrasound velocity, and dentin tubule size and density. t ... | 2006 | 16460346 |
| building on existing models from human medical education to develop a communication curriculum in veterinary medicine. | communication is a core clinical skill of veterinary medicine and one that needs to be taught and learned to the same degree as other clinical skills. to provide this education and essential expertise, veterinary schools in many countries, especially including north america, the united kingdom, and australia, have begun to develop programs and communication curricula. human medical education, however, has 30 years' experience in developing communication curricula, and is thus an excellent resour ... | 2006 | 16767635 |
| site-specific cytosine methylation in s-comt promoter in 31 brain regions with implications for studies involving schizophrenia. | the catechol-o-methyltransferase (comt) gene on chromosome 22q11 has been considered a strong candidate gene for schizophrenia (sz) susceptibility. a functional val/met polymorphism in exon 4, with potential to affect comt activity has been implicated in sz, but the results remain inconclusive. we hypothesized that the association of comt gene with sz is not strictly a genetic alteration but could involve dna methylation, as an epigenetic alteration. thus, we chose to examine the cytosine dna me ... | 2005 | 15635661 |
| cost of severe haemophilia in toronto. | our objective was to determine costs and trends in treating boys with severe haemophilia a before our centre routinely used prophylaxis. one reviewer extracted data from patient charts to determine resource consumption for 17 boys with severe haemophilia a from 1978 to 1998 at toronto's hospital for sick children. resources included factor concentrate, doctors and health care professionals (physiotherapists/social workers), tests (laboratory, radiological and diagnostic) and hospitalizations. su ... | 2005 | 15876271 |
| determining the sex of human remains through cranial morphology. | sex determination is the keystone of a biological profile, yet few qualitative methods of cranial sex determination have been tested. this analysis examines the accuracy and precision of 17 morphological features of the skull commonly used to determine the sex of unknown skeletal remains. the sample consists of 46 identified skulls from the 19th century st. thomas' anglican church cemetery in belleville, canada. nasal aperature, zygomatic extension, malar size/rugosity, and supraorbital ridge pr ... | 2005 | 15932077 |
| designing effective human-automation-plant interfaces: a control-theoretic perspective. | in this article, we propose the application of a control-theoretic framework to human-automation interaction. the framework consists of a set of conceptual distinctions that should be respected in automation research and design. we demonstrate how existing automation interface designs in some nuclear plants fail to recognize these distinctions. we further show the value of the approach by applying it to modes of automation. the design guidelines that have been proposed in the automation literatu ... | 2005 | 15960084 |
| setting up a mobile dental practice within your present office structure. | different service models have emerged in canada and the united states to address the issue of senior citizens' lack of access to comprehensive dental care. over the past decade, one such model, the use of mobile dental service units, has emerged as a practical strategy. this article describes a mobile unit, operated as an adjunct to the general practitioner's office and relying mainly on existing office resources, both human and capital, to deliver services at long-term care institutions. the es ... | 2005 | 15691425 |
| persevering through a difficult time during the sars outbreak in toronto. | the purpose of this study was to describe the experience of persevering through a difficult time for patients, family members of patients, nurses, and allied health professionals during the severe acute respiratory syndrome outbreak. van kaam's phenomenological research method, with the human becoming theory as the theoretical perspective, was used to gather and analyse data from 63 participants who agreed to describe a situation that illuminated their experience of persevering through a difficu ... | 2005 | 16210748 |
| reunification of child and animal welfare agencies: cross-reporting of abuse in wellington county, ontario. | institutional change has resulted in the separation of organizations for the protection of animals and children. this project reunites two organizations to examine associations between human violence and animal cruelty. for 12 months, family and children's services (fcs) investigators and humane society (hs) investigators in wellington county, canada, completed checklists to examine connections between forms of violence. fcs workers found some cause for concern in 20% of 1,485 homes with an anim ... | 2005 | 15717773 |
| perfluorinated sulfonamides in indoor and outdoor air and indoor dust: occurrence, partitioning, and human exposure. | perfluorinated alkyl sulfonamides (pfass) which are used in a variety of consumer products for surface protection were investigated through a comprehensive survey of indoor air, house dust, and outdoor air in the city of ottawa, canada. this study revealed new information regarding the occurrence and indoor air source strength of several pfass including n-methylperfluorooctane sulfonamidoethanol (mefose), n-ethylperfluorooctane sulfonamidoethanol (etfose), n-ethylperfluorooctane sulfonamide (etf ... | 2005 | 16190217 |
| triploidy identified through second-trimester serum screening. | to describe the maternal serum marker patterns of triploid pregnancies and estimate the second-trimester prevalence of triploidy. | 2005 | 15791661 |
| influenza and emergency department utilization by elders. | influenza outbreaks have been associated with worsened emergency department (ed) crowding. we sought to examine the mechanism behind this association. | 2005 | 15805325 |
| human p53 tumor suppressor gene (tp53) and schizophrenia: case-control and family studies. | the human p53 tumor suppressor gene (tp53) is considered as a candidate susceptibility gene for schizophrenia because of its functions in neurodevelopment. to test for an association between tp53 and schizophrenia, both the case-control study and the transmission disequilibrium test (tdt) were performed on genotype data from eight polymorphisms in tp53. our samples included 286 toronto schizophrenia cases and 264 controls, and 163 portuguese nuclear families. in the toronto case-control study si ... | 2005 | 16039051 |
| surveillance for laboratory-confirmed influenza requiring hospital admission in adults, metropolitan toronto and peel region, 2004-2005 influenza season. | 2005 | 16669120 | |
| costs of colposcopy services and their impact on the incidence and mortality rate of cervical cancer in canada. | organized cervical cancer screening services consisting of conventional papanicolaou cervical smears, colposcopy, and related treatment modalities are readily available in all provinces. the purpose of this report was to study the impact of colposcopy usage and costs on cervical cancer incidence and mortality rates in several canadian provinces. knowledge of such information is essential before newer technology such as liquid-based cytology and human papillomavirus testing is introduced or repla ... | 2005 | 16044056 |
| association of seek1 and psoriatic arthritis in two distinct canadian populations. | to examine the relationship between snp +39604 in seek1 and psoriatic arthritis (psa) in two distinct canadian populations. | 2005 | 15708881 |
| disability management practices in education, hotel/motel, and health care workplaces. | the high costs and the impact of work disability have become a growing concern for workplaces. as a result, workplace disability management approaches have been developed to lower disability costs, protect the employability of workers, and promote early return to work. | 2005 | 15712255 |
| beliefs and practices of ontario midwives about influenza immunization. | with an increasing number of births in ontario being conducted by midwives, we undertook a survey of the beliefs and practices of 256 licensed ontario midwives and student midwives about immunization, particularly against influenza. overall, 42.9% (48/112) of midwives considered that they knew a lot about immunization; however, 36.2% (38/105) reported no education about immunization during their training. a small majority (55.9%) were in favour of vaccination in general and only 2 of 113 reporte ... | 2005 | 15694509 |
| registered nurse and registered practical nurse evaluations of their hospital practice environments and their responses to these environments. | in 2003, over 13,000 ontario nurses were surveyed to explore how they evaluated their hospital work environments and their responses to these practice environments. the purpose of this paper is to describe and compare these nurses' evaluations and responses. sixty-five percent of nurses who were mailed surveys completed and returned a survey. significant differences were found between registered nurse and registered practical nurse characteristics such as mean age, full-time employment rates, me ... | 2005 | 16463646 |
| defining needs-based urban health planning areas is feasible and desirable: a population-based approach in toronto, ontario. | reporting health data for large urban areas presents numerous challenges. in the case of toronto, ontario, amalgamation in 1998 merged six census subdivisions into one mega-city, resulting in the disappearance of standard reporting units. a population-based approach was used to define new health planning areas. census tracts were used as building blocks and combined according to residential income homogeneity, respecting natural and man-made boundaries, forward sortation areas and the city of to ... | 2005 | 16238159 |
| occurrence of perfluorosulfonates and other perfluorochemicals in dust from selected homes in the city of ottawa, canada. | a series of perfluorinated compounds (pfcs) including perfluorooctane sulfonate (pfos) and perfluorooctanoic acid (pfoa) have been recently measured in a variety of environmental samples and biological matrices. in order to better understand the human exposure routes of these chemicals, levels of pfos, pfoa, perfluorobutane sulfonate (pfbs), perfluorohexane sulfonate (pfhs) and perfluorooctane sulfonamide (pfosa) in house dust samples were investigated. the data revealed a correlation between th ... | 2005 | 16252056 |
| the development and validation of equations to predict grip force in the workplace: contributions of muscle activity and posture. | the inherent difficulty of measuring forces on the hand in ergonomic workplace assessments has led to the need for equations to predict grip force. a family of equations was developed, and validated, for the prediction of grip force using forearm electromyography (six finger and wrist muscles) as well as posture of the wrist (flexed, neutral and extended) and forearm (pronated, neutral, supinated). inclusion of muscle activity was necessary to explain over 85% of the grip force variance and was ... | 2005 | 16253943 |
| determinants of health-service use by low-income people. | poverty influences health status, life expectancy, health behaviours, and use of health services. this study examined factors influencing the use of health-related services by people living in poverty. in the first phase, 199 impoverished users of health-related services in 2 large canadian cities were interviewed by their peers. in the second phase, group interviews with people living in poverty (n = 52) were conducted. data were analyzed using thematic content analysis. diverse health-related ... | 2005 | 16268092 |
| challenges and strategies related to hearing loss among dairy farmers. | farming is often imagined to be a serene and idyllic business based on historical images of a man, a horse, and a plow. however, machinery and equipment on farms, such as older tractors, grain dryers, and vacuum pumps, can have noise levels, which may be dangerous to hearing with prolonged, unprotected exposure. | 2005 | 16294656 |
| natural abundance of sb and sc in pristine groundwaters, springwater township, ontario, canada, and implications for tracing contamination from landfill leachates. | using icp-sms and the clean lab methods and procedures developed for determining trace element concentrations in polar snow and ice, a lower limit of detection (lod) of 30 pg l(-1) for sb and 5 pg l(-1) for sc was achieved, allowing the natural abundances of sb and sc to be measured in pristine groundwaters. water samples were collected from natural flows and wells between elmvale and wyevale in springwater township, ontario, canada. the water in this region is derived from chemical reactions be ... | 2005 | 16307077 |
| conceptual accessibility and sentence production in a free word order language (odawa). | the study reported here was conducted in the algonquian language of odawa (a.k.a. ottawa), with the goal of gaining new insight into the ways that conceptual accessibility affects human sentence production. the linguistic characteristics of odawa are quite different from those found in the languages most often examined by psycholinguists. the data obtained from the sentence production experiment reported here are thus relevant to production in a heretofore unexamined language. moreover, the data ... | 2005 | 16307955 |
| reconstruction of human optic nerve heads for finite element modeling. | glaucoma is a common ocular disease whose pathogenesis is hypothesized to involve biomechanical damage to optic nerve tissues. here we describe a method for the construction of patient-specific models that can be used to evaluate the biomechanical environment within the optic nerve head. we validate the method using a virtual eye, and demonstrate its use in computing optic nerve head biomechanics. | 2005 | 16055979 |
| acute care hospital strategic priorities: perceptions of challenges, control, competition and collaboration in ontario's evolving healthcare system. | to explore the current and pending strategic agenda of ontario hospitals (the largest consumers of the provincial healthcare budget), a survey of ontario acute care hospital ceos was conducted in january 2004. the survey, with an 82% response rate, identifies 29 strategic priorities under seven key strategic themes consistent across different hospital types. these themes include (1) human resources cultivation, (2) service integration and partnerships, (3) consumer engagement, (4) corporate gove ... | 2005 | 16078398 |
| full-time or part-time work in nursing: preferences, tradeoffs and choices. | nursing human resources are limited; thus, effective deployment of personnel is essential to optimize staff capacity. the nursing profession competes for staff in environments where human capital is at a premium. to maximize recruitment and retention, it is imperative that nurses' work preferences be taken into account. | 2005 | 16078406 |
| is house dust the missing exposure pathway for pbdes? an analysis of the urban fate and human exposure to pbdes. | polybrominated diphenyl ether (pbde) body burdens in north america are 20 times that of europeans and some "high accumulation" individuals have burdens up to 1-2 orders of magnitude higher than median values, the reasons for which are not known. we estimated emissions and fate of sigma pbdes (minus bde-209) in a 470 km2 area of toronto, canada, using the multi-media urban model (mum-fate). using a combination of measured and modeled concentrations for indoor and outdoor air, soil, and dust plus ... | 2005 | 16082939 |
| the snap25 gene as a susceptibility gene contributing to attention-deficit hyperactivity disorder. | the synaptosomal-associated protein of 25 kda gene (snap25) has been suggested as a genetic susceptibility factor in attention-deficit hyperactivity disorder (adhd) based on the mouse strain coloboma. this strain is hemizygous for the snap25 gene and displays hyperactivity that responds to dextroamphetamine, but not to methylphenidate. previously, we reported association of snap25 and adhd using two polymorphisms. to further investigate this gene, we screened the exons for dna variation and geno ... | 2005 | 16088329 |
| human immunodeficiency virus, hepatitis b, and hepatitis c seroprevalence in a canadian trauma population. | the current seroprevalence of human immunodeficiency virus (hiv), hepatitis b, and hepatitis c in the canadian trauma population is unknown. establishing the seroprevalence of these diseases is vital for education, postexposure prophylaxis, and counseling, and to establish potential screening guidelines. the purpose of this study was to determine the seroprevalence of hiv, hepatitis b, and hepatitis c in the trauma population of london, ontario, canada. | 2005 | 16096548 |
| clinical kidney transplantation: a 50th anniversary review of the first reported series. | histories of kidney transplantation rarely mention a series reported by gordon murray of toronto and published by the american journal of surgery 50 years ago. | 2005 | 16105541 |
| workplace organizational policies and practices in ontario educational facilities. | workplace organizational policies and practices (opps) play a pivotal role in managing injury and disability. this study identifies the workplace opps in ontario's education sector. | 2005 | 16119231 |
| the mid-canada radar line and first nations' people of the james bay region, canada: an evaluation using log-linear contingency modelling to analyze organochlorine frequency data. | abandoned radar line stations in the north american arctic and sub-arctic regions are point sources of contamination, especially for pcbs. few data exist with respect to human body burden of organochlorines (ocs) in residents of communities located in close proximity to these radar line sites. we compared plasma oc concentration (unadjusted for total lipids) frequency distribution data using log-linear contingency modelling for fort albany first nation, the site of an abandoned mid-canada radar ... | 2005 | 16121269 |
| a comparison of systemwide and hospital-specific performance measurement tools. | balanced scorecards are being implemented at the system and organizational levels to help managers link their organizational strategies with performance data to better manage their healthcare systems. prior to this study, hospitals in ontario, canada, received two editions of the system-level scorecard (sls)--a framework, based on the original balanced scorecard, that includes four quadrants: system integration and management innovation (learning and growth), clinical utilization and outcomes (i ... | 2005 | 16130808 |
| human torovirus: a new virus associated with neonatal necrotizing enterocolitis. | toroviruses have been associated with gastroenteritis in both animals and humans. the aim of this study was to examine the fecal excretion of torovirus in infants with necrotizing enterocolitis (nec). | 2005 | 16188853 |
| croup hospitalizations in ontario: a 14-year time-series analysis. | croup is the most common form of airway obstruction in children. known to be primarily viral, the seasonality of croup has been examined largely through its association with the human parainfluenza viruses. this study examined the seasonal pattern of croup hospitalizations in relation to age and gender for the province of ontario during a 14-year period. | 2005 | 15995030 |
| the demise of repetitive strain injury in sceptical governing rationalities of workplace managers. | in the mid-1990s, rsi (repetitive strain injury) loomed as an occupational health epidemic in industrialised countries. a decade later, the problem appears to have faded away, but there has been little explanation for how this problem might have diminished. this paper offers an explanation for the decline of rsi in the social relations of workplaces, in the pragmatic, day-to-day governance of occupational health by workplace managers. using the conceptual lens of governmentality theory, this stu ... | 2005 | 15998348 |
| risk of hypertension and reduced kidney function after acute gastroenteritis from bacteria-contaminated drinking water. | the long-term health consequences of acute bacterial gastroenteritis remain uncertain. we studied the risk of hypertension and reduced kidney function after an outbreak of acute gastroenteritis due to contamination of a regional drinking water supply with escherichia coli o157:h7 and campylobacter species. | 2005 | 15923490 |
| bayesian ranking of sites for engineering safety improvements: decision parameter, treatability concept, statistical criterion, and spatial dependence. | in recent years, there has been a renewed interest in applying statistical ranking criteria to identify sites on a road network, which potentially present high traffic crash risks or are over-represented in certain type of crashes, for further engineering evaluation and safety improvement. this requires that good estimates of ranks of crash risks be obtained at individual intersections or road segments, or some analysis zones. the nature of this site ranking problem in roadway safety is related ... | 2005 | 15949462 |
| foliar phenolics in sugar maple (acer saccharum) as a potential indicator of tropospheric ozone pollution. | tropospheric o3 has been implicated in the declining health of forest ecosystems in europe and north america and has been shown to have negative consequences on human health. we have measured tropospheric ozone (o3) in the lower canopy through the use of passive monitors located in five woodlots along a 150 km urban-rural transect, originating in the large urban complex of toronto, canada. we also sampled foliage from 10 mature sugar maple trees in each woodlot and measured the concentration of ... | 2005 | 15952532 |
| methicillin-resistant staphylococcus aureus in horses and horse personnel, 2000-2002. | methicillin-resistant staphylococcus aureus (mrsa) infection was identified in 2 horses treated at a veterinary hospital in 2000, prompting a study of colonization rates of horses and associated persons. seventy-nine horses and 27 persons colonized or infected with mrsa were identified from october 2000 to november 2002; most isolations occurred in a 3-month period in 2002. twenty-seven (34%) of the equine isolates were from the veterinary hospital, while 41 (51%) were from 1 thoroughbred farm i ... | 2005 | 15757559 |
| [hnf-1alpha g319s mutation in oji-cree type 2 diabetes]. | 2005 | 15779364 | |
| pesticides and human health: why public health officials should support a ban on non-essential residential use. | the college of family physicians of ontario recently released a comprehensive report on pesticide exposure and health risk, concluding that various pesticides had adverse health effects. the pesticide industry says that pesticides are "safe" when used as directed because they are studied and approved by governmental agencies. yet many municipalities, including canada's three largest, and the province of quebec have enacted bans on cosmetic use of pesticides, largely in response to health concern ... | 2005 | 15850024 |
| ensuring a broad and inclusive approach: a provincial perspective on pandemic preparedness. | the sars crisis revealed critical gaps in ontario's health emergency response capacity, and identified, in the starkest terms possible, the need for improved emergency response planning. this article reviews the development of the ontario health plan for an influenza pandemic (ohpip), released in june 2005. some key points arising from the provincial planning process include the necessity to: ensure a broad and inclusive development process; ensure the pandemic plan identifies: 1) clear roles an ... | 2005 | 16350862 |
| the effect of fetal gender on the false-positive rate of down syndrome by maternal serum screening. | (1) to further explore if there is a difference in maternal serum levels of alpha-fetoprotein (afp), human chorionic gonadotrophin (hcg) and estriol (ue3) between fetal genders. (2) to determine if these differences influence false-positive rates of down syndrome screening in pregnancies with male or female fetuses. | 2005 | 16353275 |
| hiv/aids in the courts--canada. criminal law and hiv transmission or exposure: one new case. hiv-positive man receives three years in prison for unprotected sex. | 2005 | 16370034 | |
| the human factor: unexpected benefits of a cpoe and electronic medication management implementation at the university health network. | 2005 | 16334080 | |
| the prevalence and clinical characteristics of cystic fibrosis in south asian canadian immigrants. | cystic fibrosis (cf) is considered to be rare among individuals from the indian subcontinent. furthermore, affected individuals are reported to experience a more severe clinical course. | 2005 | 15970608 |
| association of the lymphoid tyrosine phosphatase r620w variant with rheumatoid arthritis, but not crohn's disease, in canadian populations. | a single-nucleotide polymorphism in the ptpn22 gene encoding the lymphoid protein tyrosine phosphatase (lyp) has recently been identified as a functional variant associated with susceptibility to rheumatoid arthritis (ra), type 1 diabetes, and systemic lupus erythematosus. to determine whether association of this variant (ptpn22 1858t) with ra is reproducible and is also observed in another autoimmune condition, crohn's disease, we investigated the association between the ptpn22 1858t allele and ... | 2005 | 15986374 |
| a framework for mobile healthcare answers to chronically ill outpatient non-adherence. | non-adherence (also known as 'non-compliance') is a major barrier undermining healing efforts within out-of-hospital self-management programmes, resulting in waste of human and social resources. this study suggests a theoretical framework of activities through which mobile patient solutions might address non-adherence determinants in a broader context of clinical interventions. the goal of the paper is to explore a dilemma associated with such interventions: the uncertainty regarding the level o ... | 2005 | 15992499 |
| individual rights? public responsibility? public health in the balance. | 2005 | 16625787 | |
| synoptic weather patterns and modification of the association between air pollution and human mortality. | to assess whether meteorological conditions modify the relationship between short-term exposure to ambient air pollution and mortality, an examination of air pollution and human mortality associations (ecologic) using hybrid spatial synoptic classification procedures was conducted. concentrations of air pollutants and human mortality from all non-accidental and cardiorespiratory causes were examined according to typical winter and summer synoptic climatologies in toronto, canada, between 1981 an ... | 2005 | 16416752 |
| neuroregenerative gene therapy: the implications for informed consent laws. | 2005 | 16736945 | |
| pulmonary pathology of severe acute respiratory syndrome in toronto. | the severe acute respiratory syndrome (sars) pandemic in toronto resulted in a large number of autopsies on its victims. we describe the pulmonary pathology of patients who died in the 2003 toronto outbreak. autopsy material from the lungs of 20 patients who died between march and july 2003 were characterized by histology, molecular biology, and immunohistochemistry for cytokeratins, thyroid transcription factor-1, cd68, epstein-barr virus, cytomegalovirus, and human herpes simplex viruses. matc ... | 2005 | 15272286 |
| outpatient chemotherapy administration: decreasing wait times for patients and families. | increasingly, there is a trend to deliver chemotherapy, where possible, in the outpatient ambulatory setting. in the few studies that have explored the setting of cancer care, long wait times are frequently linked to dissatisfaction. several factors contribute to lengthy waiting times for patients and their families: long registration processes, lag times associated with obtaining laboratory results, time required for patient assessments and preparation of chemotherapeutic agents, adequacy of nu ... | 2005 | 15574724 |
| pcb exposure and in vivo cyp1a2 activity among native americans. | cytochrome p-450 1a2 (cyp1a2) is an enzyme involved in the metabolic activation of some carcinogens and is believed to be induced by xenobiotics. very few studies, however, have investigated the association between environmental exposures and in vivo cyp1a2 activity in humans. to address this issue, a study was conducted of cyp1a2 activity among native americans exposed to polychlorinated biphenyls (pcbs) from the consumption of fish from the st. lawrence river. at the mohawk nation at akwesasne ... | 2005 | 15743714 |
| home chemotherapy for children with cancer: perspectives from health care professionals. | the goal of this study was to determine the perspectives of healthcare professionals (hps) from community and hospital settings involved in a paediatric home chemotherapy programme. using a prospective descriptive study design, hps including paediatricians, community nurses, hospital clinic nurses, administrators and pharmacists were interviewed using a moderately structured open-ended approach. through inductive content analysis, data were categorised under three themes reflecting hps' perspect ... | 2004 | 19777723 |
| levels of citation of nonhuman animal studies conducted at a canadian research hospital. | the publication of scientific articles that receive few or no citations raises questions of the appropriate use of resources as well as ethics. in the case of animal research, the ethics issue extends beyond human patients to nonhuman animals, as the research subjects them to pain and, typically, to death. this study is a citation analysis of animal research conducted at toronto's hospital for sick children (hsc). of the 594 publications (1990 to 1995) on animal research by affiliates of hsc, 29 ... | 2004 | 15498728 |
| association between biallelic and monoallelic germline myh gene mutations and colorectal cancer risk. | the muty human homologue (myh) gene encodes a member of the base excision repair pathway that is involved in repairing oxidative damage to dna. two germline myh gene mutations that result in myh proteins containing amino acid substitutions y165c and g382d (hereafter called the y165c and g382d mutations) are associated with adenomatous poly-posis and colorectal cancer among patients from several european poly-posis registries. we used a population-based series of 1238 colorectal cancer patients a ... | 2004 | 15523092 |
| obesity research in canada: literature overview of the last 3 decades. | to identify research published on obesity in canada, to explore the range of areas studied, and to identify gaps and areas that merit future research attention. | 2004 | 15536218 |
| passive sampling survey of polybrominated diphenyl ether flame retardants in indoor and outdoor air in ottawa, canada: implications for sources and exposure. | the polybrominated diphenyl ethers (pbdes) are widely used as flame retardants in plastics of soft furnishings, tv sets and computers, and insulation in the indoor environment. the penta-bdes--now banned in most parts of europe but still used in north america--are additive flame retardants that may be released to the indoor environment via volatilization or as dusts. in this study, to investigate general population pbde exposure, air was sampled in 74 randomly selected homes in ottawa, canada an ... | 2004 | 15543731 |
| perfluoroalkyl contaminants in a food web from lake ontario. | perfluorooctane sulfonate (pfos) is a persistent and bioaccumulative perfluorinated acid detectable in humans and wildlife worldwide that has alerted scientists to examine the environmental fate of other fluorinated organic contaminants. recently a homologous series of perfluoroalkyl carboxylates (pfcas) was detected in the arctic, yet little is known about their sources, breadth of contamination, or environmental distribution. in this study we analyzed for pfos, the homologous series of pfcas r ... | 2004 | 15543740 |
| report of the 2003 pan-canadian forum on cervical cancer prevention and control. | to develop evidence-based consensus recommendations on the delivery of cervical cancer screening, human papillomavirus (hpv) education, hpv testing, and the optimal tool for cervical cytology within the canadian health system. | 2004 | 15560864 |
| stem cell research and transplantation: science leading ethics. | one of the most exciting developments in the biological sciences in the past decade has been the discovery and characterization of human embryonic stem cells (escs). the interest to transplanters is the potential applications of stem cells in regenerative medicine (rm), which may involve tissue engineering, genetic engineering, and other techniques to repair, replace, or regenerate failing tissues and organs. there is little controversy surrounding human adult stem cells. however, human escs are ... | 2004 | 15561296 |
| blurring the boundaries of space: shaping nursing lives at the red cross outposts in ontario, 1922-1945. | historians and other scholars interested in the history of hospitals have investigated the links between medical architecture and the organization of space with the evolution of modern medicine. the transformation over time in the architectural for of medical institutions has tended to reflect developments in medical science and therapeutic efficiency as well as elements in the broader social climate. some authors, however, have argued for the agency of structure and spatial organization, to con ... | 2004 | 15568264 |
| isolation of methicillin-resistant staphylococcus aureus from the environment in a veterinary teaching hospital. | after recognition of a cluster of methicillin-resistant staphylococcus aureus (mrsa) infection in horses and humans at the ontario veterinary college veterinary teaching hospital, environmental contamination with mrsa was evaluated. a total of 260 environmental surfaces were sampled during periods when mrsa-infected horses were hospitalized, and mrsa was isolated from 25/260 sites (9.6%). the most commonly contaminated sites were stalls housing mrsa-positive horses, but other stalls, medical equ ... | 2004 | 15320581 |
| effectiveness of inactivated trivalent influenza vaccine in long-term care institutions, toronto, 2003-2004. | 2004 | 15239482 | |
| an advisory committee statement (acs). national advisory committee on immunization (naci). statement on influenza vaccination for the 2004-2005 season. | 2004 | 15239483 | |
| development and assessment of the canadian personal load carriage system using objective biomechanical measures. | the defence research and development canada--toronto managed a collaborative team of designers, biomechanists, ergonomists and military stakeholders in the development of a new personal load carriage (lc) system for the canadian forces. ergonomics design principles using objective measurement tools and user-centred feedback from soldiers were considered essential to system development. the purpose of this study was to provide a detailed report of contributions by biomechanical testing to the fin ... | 2004 | 15370846 |
| a suite of objective biomechanical measurement tools for personal load carriage system assessment. | for application to military and civilian needs, defence research and development canada--toronto contracted queen's university, kingston to develop a suite of biomechanical assessment and analytical tools to supplement human-based load carriage system assessment methods. this suite of tools permitted efficient objective evaluation of biomechanical aspects of load-bearing webbing, vests, packs and their components, and therefore contributed to early system assessment and a rapid iterative design ... | 2004 | 15370854 |
| antidepressant medication use and non-hodgkin's lymphoma risk: no association. | animal and human studies have suggested that antidepressant medications may be associated with several cancers. the authors evaluated the association between antidepressant medication use and the risk of non-hodgkin's lymphoma using a canadian population-based case-control study, the national enhanced cancer surveillance study. non-hodgkin's lymphoma cases (n=638) diagnosed in 1995-1996 were identified using the ontario cancer registry, and controls (n=1,930) were identified from the ontario min ... | 2004 | 15353417 |
| effect of 4-aminopyridine on gait in ambulatory spinal cord injuries: a double-blind, placebo-controlled, crossover trial. | animal and human research have shown that the drug 4-aminopyridine (4-ap) may improve gait in spinal cord lesions by enhancing nerve transmission to affected muscles. | 2004 | 15356676 |
| responding to pandemic influenza: a local perspective. | to assess, via a tabletop exercise, the ability of a rural health unit to manage an influenza pandemic. | 2004 | 14768738 |
| noninvasive phenotypes of atherosclerosis: similar windows but different views. | noninvasive measures of atherosclerosis, such as carotid intima-media thickness, total carotid plaque area, and carotid stenosis, probably represent different phenotypes with distinct determinants. for instance, total carotid plaque area may reflect atherosclerotic lesion size more closely than carotid stenosis, which instead may reflect hemodynamic compromise within the arterial lumen. | 2004 | 14963285 |
| the urban geography of sars: paradoxes and dilemmas in toronto's health care. | severe acute respiratory syndrome (sars) has impacted heavily on both canada's society and its health care system. quite unexpectedly, hospitals and health care workers became facilitators of disease diffusion. this experience has demonstrated the need for a comprehensive disease control strategy. | 2004 | 15012634 |
| radiation treatment of lung cancer--patterns of practice in canada. | to assess the patterns of practice among canadian radiation oncologists who treat lung cancers. | 2004 | 15110450 |
| gastrointestinal bleeding after the introduction of cox 2 inhibitors: ecological study. | 2004 | 15138157 | |
| criteria to assess and select sites for long-term avian monitoring in an urbanizing landscape. | a methodology was developed to prioritize the suitability of sites for long-term monitoring of avian populations, including vulnerable species, both to enhance assessment of changes in ecological resources and to facilitate land-use planning at the regional scale. this paper argues that a successful monitoring program begins with a site prioritization procedure that integrates scores based on spatial controls with ecological and socio-economic indicators, particularly those dependent on communit ... | 2004 | 15141452 |
| analysis of the novel tph2 gene in bipolar disorder and suicidality. | 2004 | 15197398 | |
| neurological manifestations of west nile virus infection. | over the past four years, west nile virus (wnv) has become a significant health issue in north america. in 2002, wnv infection made its first appearance in the human population in canada. | 2004 | 15198442 |
| association between schizophrenia and the syntaxin 1a gene. | both microarray and candidate molecule studies have demonstrated that protein and mrna expression of syntaxin and other genes involved in synaptic function are altered in the cerebral cortex of patients with schizophrenia. | 2004 | 15219469 |
| community influenza outbreaks and emergency department ambulance diversion. | influenza has been linked to emergency department (ed) crowding, yet few studies have examined this association. we describe the relationship between ed crowding and influenza outbreaks. | 2004 | 15226710 |
| current man-made mineral fibers (mmmf) exposures among ontario construction workers. | current occupational exposures to man-made mineral fibers (mmmf), including refractory ceramic fibers (rcf), were measured as part of an exposure assessment program for an epidemiological study pertaining to cancer and mortality patterns of ontario construction workers. the assessments were carried out at commercial and residential sites. a total of 130 mmmf samples (104 personal and 26 area) was collected and included 21 rcf (16 personal and 5 area). the samples were analyzed by the world healt ... | 2004 | 15238339 |
| family cancer histories predictive of a high risk of hereditary non-polyposis colorectal cancer associate significantly with a genomic rearrangement in hmsh2 or hmlh1. | hereditary non-polyposis colorectal cancer (hnpcc) results from inactivating germline mutations in a set of dna-mismatch-repair genes, of which the most clinically relevant are hmsh2 and hmlh1. computer-assisted pedigree risk assessment tools are available to assist in the calculation of an individual's likelihood of bearing such a deleterious mutation. one such tool, cancergene version 3.4 (http://www3.utsouthwestern.edu/cancergene) was used to assess the risk of a deleterious mutation in the g ... | 2004 | 15324316 |
| influenza and pneumonia hospitalizations in ontario: a time-series analysis. | a comprehensive examination of gender and age-specific influenza and pneumonia hospitalization seasonality is currently lacking. using population-based data for ontario, canada between april 1988 and march 2002 (n = 339,803 hospitalizations), findings from this study revealed clear seasonality [fisher's kappa (fk) test = 68.64, p < 0.001; bartlett's kolmogorov-smirnov (bks) test = 0.68, p < 0.001] with consistent summer troughs and winter peaks for both sexes and all ages combined. the very youn ... | 2004 | 15635976 |
| rates of influenza vaccination in older adults and factors associated with vaccine use: a secondary analysis of the canadian study of health and aging. | influenza vaccination has been shown to reduce morbidity and mortality in the older adult population. in canada, vaccination rates remain suboptimal. we identified factors predictive of influenza vaccination, in order to determine which segments of the older adult population might be targeted to increase coverage in influenza vaccination programs. | 2004 | 15306030 |
| the story behind the story of collaborative networks -- relationships do matter! | this study reports data about the real story behind the current trend of mandated interorganizational collaboration of health and human service agencies. by means of qualitative design (n-22), public health managers were interviewed about the extent and nature of their collaborative efforts in the healthy babies, healthy children (hbhc) program in ontario, canada. using a conceptual framework of resource exchange theory, this study found that relational processes specifically: (a) previous relat ... | 2004 | 15829450 |
| addressing the realities [correction of realties] of health care in northern aboriginal communities through participatory action research. | to address concerns about disruptions in the continuity of health care delivered to residents in three remote aboriginal communities in northern ontario, canada, the local health authority initiated a study in collaboration with the department of health canada responsible for ensuring that aboriginal reserves receive mandatory health services, and an inter-disciplinary team of researchers from two universities. the study focussed on the delivery of oncology, diabetes and mental health care, spec ... | 2004 | 15801551 |
| the changing costs of radiation treatment for early prostate cancer in ontario: a comparison between conventional and conformal external beam radiotherapy. | prostate cancer represents a large part of the workload for radiation oncology departments in canada. recent evidence suggests that conformal external beam radiotherapy improves results. the planning and treatment process for conformal patients requires a greater amount of resources that are in short supply in ontario. an understanding of these differences is important to provide an accurate estimate of future radiation needs of the province. these differences can be quantified in a cost model t ... | 2004 | 15003151 |
| work-related disability in canadian nurses. | to determine factors contributing to high registered nurse (rn) injury claim rates in canadian hospitals. | 2004 | 15636416 |
| the role of patients in designing health information systems: the case of applying simulation techniques to design an electronic patient record (epr) interface. | one overall objective of electronic patient records (eprs) is to improve patient education and to enhance the patient experience through the use of information technology (it) so as to facilitate the sharing of information between providers and their patients. the research project reported on herein took place at university health network (uhn) in toronto (canada), which is a large academic health science center with multiple hospital sites in the city. as a first step in this process, we examin ... | 2004 | 15717812 |
| canada: national summit on "global health is a human right"! | held in ottawa on 21-22 may 2003, a national summit on "global health is a human right!" brought together 86 people representing over 60 canadian civil society groups interested in joint advocacy on realizing the human right to health in developing countries. the summit focused particularly on addressing the global crises of communicable diseases such as hiv/aids, tuberculosis, and malaria. | 2003 | 14746307 |
| antidepressant medication use and breast cancer risk: a case-control study. | animal and human studies have reported an association between antidepressant (ad) medication use and breast cancer risk. a population-based case-control study was designed specifically to examine this association among women in ontario, canada. | 2003 | 14681256 |
| prior opiate injection and incarceration history predict injection drug use among inmates. | to describe injection drug use among inmates, and to identify correlates of drug injection while incarcerated. | 2003 | 12930213 |
| current chemical exposures among ontario construction workers. | current occupational exposures to chemical agents were assessed as part of an epidemiological study pertaining to the cancer and mortality patterns of ontario construction workers. the task-based exposure assessment involved members from nine construction trade unions. air samples were taken using personal sampling pumps and collection media. a dusttrak direct-reading particulate monitor was also employed. exposure assessments included measurements of airborne respirable, inhalable, total, and s ... | 2003 | 14612300 |
| drive thru, prevent flu. | 2003 | 14638665 |