Publications

propagation of rabies virus in tissue culture.	rabies virus has been propagated in serum-tyrode solution containing either embryo mouse brain or embryo chick brain. the culture virus reached a titre of 3 x 10(-5) cc. after 4 days' incubation at 37 degrees c., and survived at least 2 months at 5 degrees c. in the liquid or dry state.	1937	19870646
propagation of rabies virus in tissue culture and the successful use of culture virus as an antirabic vaccine.		1936	17781073
further studies in anti-rabies immunisation. rabies virus-exalted and classical strains compared.		1931	20475112
immunological studies with herpes virus with a consideration of the herpes-encephalitis problem.	in the preceding experiments observations have been reported upon the nature of herpes virus which confirm the suspicion that the virus is intracellularly located in the infected nervous system. in regard to the immunological conditions existing in this disease, our experiments have reaffirmed that herpes virus can be neutralized with the serum of actively immunized animals and have offered an explanation for the irregularity of the results of others, as well as our own. it has been found that b ...	1926	19869171
internalization and fusion mechanism of vesicular stomatitis virus and related rhabdoviruses.	members of the rhabdoviridae infect a wide variety of animals and plants, and are the causative agents of many important diseases. rhabdoviruses enter host cells following internalization into endosomes, with the glycoprotein (g protein) mediating both receptor binding to host cells and fusion with the cellular membrane. the recently solved crystal structure of vesicular stomatitis virus g has allowed considerable insight into the mechanism of rhabdovirus entry, in particular the low ph-dependen ...	0	23516023
evaluation of a monoclonal antibody-based rapid immunochromatographic test for direct detection of rabies virus in the brain of humans and animals.	rabies diagnosis uses a direct fluorescent antibody test (fat) that is difficult, costly, and time-consuming, and requires trained personnel. we developed a rapid immunochromatographic test (rict) for the diagnosis of rabies. the efficacy of the rict was compared with that of the fat. brain samples were collected from humans, dogs, cats, and other animals in sri lanka (n = 248), bhutan (n = 27), and thailand (n = 228). the sensitivity (0.74-0.95), specificity (0.98-1.0), positive predictive valu ...	0	22492163
encephalitis caused by pathogens transmitted through organ transplants, united states, 2002-2013.	the cause of encephalitis among solid organ transplant recipients may be multifactorial; the disease can result from infectious or noninfectious etiologies. during 2002-2013, the us centers for disease control and prevention investigated several encephalitis clusters among transplant recipients. cases were caused by infections from transplant-transmitted pathogens: west nile virus, rabies virus, lymphocytic choriomeningitis virus, and balamuthia mandrillaris amebae. in many of the clusters, iden ...	0	25148201
virus infections in the nervous system.	virus infections usually begin in peripheral tissues and can invade the mammalian nervous system (ns), spreading into the peripheral (pns) and more rarely the central (cns) nervous systems. the cns is protected from most virus infections by effective immune responses and multilayer barriers. however, some viruses enter the ns with high efficiency via the bloodstream or by directly infecting nerves that innervate peripheral tissues, resulting in debilitating direct and immune-mediated pathology. ...	0	23601101
role of reverse transcriptase polymerase chain reaction for the diagnosis of human rabies.	traditionally, rabies diagnosis is made by demonstration of rabies viral antigen by direct immunofluorescence (dif) and mouse inoculation test (mit). the present study was carried out to evaluate the role of reverse transcriptase-polymerase chain reaction (rt-pcr) in comparison with these conventional techniques for the diagnosis of rabies.	0	22825603
cxcl10 and blood-brain barrier modulation in rabies virus infection.		0	26895109
evaluation of in vitro antiviral activity of datura metel linn. against rabies virus.	the soxhlet and cold extracts of datura metel linn. were evaluated for in vitro antirabies activity.	0	27695266
rabies surveillance in the united states during 2013.	during 2013, 53 reporting jurisdictions reported 5,865 rabid animals and 3 human rabies cases to the cdc, representing a 4.8% decrease from the 6,162 rabid animals and 1 human case reported in 2012. ninety-two percent of reported rabid animals were wildlife. relative contributions by the major animal groups were as follows: 1,898 raccoons (32.4%), 1,598 bats (27.2%), 1,447 skunks (24.7%), 344 foxes (5.9%), 247 cats (4.2%), 86 cattle (1.5%), and 89 dogs (1.5%). one human case was reported from ma ...	0	25356711