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[pathogenesis of alzheimer's disease].the 160 and 200 kd phosphorylated and non-phosphorylated neurofilament monoclonal antibodies were used as the probe to study the cytoskeletal protein distribution inside cerebral neurons of 2 normal adults and 2 patients with alzheimer's disease (ad). immunocytochemical technique was applied in this study. non-phosphorylated neurofilament was located in the perikarua, whereas, the phosphorylated neurofilament was rich in the peripheral of the neuron's cell body and axons in the normal adult brai ...20002174279
titanocene dichloride--the first metallocene with cancerostatic activity. 2000111586
[digestive reconstruction after proctocolectomy]. 200097145
serum isoamylases in diseases of the lung and control subjects of thermolabile serum amylase component. 200094301
computed tomographic evaluation of the breast.experience with a dedicated breast ct scanner (general electric ct/m) using a contrast medium enhancement technique indicates that ct is superior to mammography, thermography, or physical examination for diagnosing both benign and malignant mammary disease especially in dense, thick, or fibrocystic breasts. ct is capable of diagnosing totally unsuspected early miniature carcinomas. it can identify and differentiate potential precancerous lesions from benign fibrocystic disease, and is the diagno ...200098990
immunological purification of sea urchin egg tropomyosin.the antiserum against lantern muscle tropomyosin of the sea urchin was prepared, and the presence of tropomyosin in the sea urchin egg was shown by immunodiffusion test between the antiserum and the egg tropomyosin fraction which was prepared according to the purification method for muscle tropomyosin. the sea urchin egg tropomyosin was isolated from the immuno-precipitate formed between the antiserum and the egg tropomyosin fraction. the subunit molecular weight of the egg tropomyosin was calcu ...200097282
frontiers of quantitative cytochemistry: a review of recent developments and potentials.this article attempts to describe the current state of quantitative cytochemical methods and to point out areas where, in the author's opinion, the greatest progress is either being made or can be expected. nearly 300 references to the current literature are cited.200094776
urinary proline to hydroxyproline ratio varies with age.urinary excretion of proline and hydroxyproline was studied in five groups of subjects, viz. controls, pituitary dwarfs, familial dwarfs, patients with fibrodysplasia ossificans progressive and patients with generalized scleroderma. the ratio pro/hyp in the urinary fraction precipitated with 5 parts of acetone (1 + 5 fraction) was close to one in children and youngsters in all the groups, while in adults it was higher than two. total pro/hyp does not give an accurate index of age.200092150
scanning electron microscopic observations of the development of the somites and their innervation in anuran larvae.the development of the paraxial mesoderm in tadpoles of xenopus, bufo and rana was observed with a scanning electron microscope. in addition to examination of the differentiation of the surface and the interior of the somites, some attention was also paid to the transformation of the material of the neural crests and to the innervation of the developing myotome.200097358
[nursing report. programs for clinical training of adult nursing (surgical nursing)]. 200087545
adrenal failure in bronchial asthma. 20004723481
the non-removable "bite plate". 2000101560
[follow-up study of glioblastoma--a review of 179 cases (author's transl)]. 200086960
experimental analysis of the 'happy hour": effects of purchase price on alcohol consumption.an experimental analogue of a discount drink policy known as the "happy hour" was used to study the effects of purchase price on drinking behavior. male volunteers with a prior history of either casual (n=20) or heavy (n=14) drinking were given free access to beverage alcohol during a 20-day period. approximately half the subjects could purchase alcohol under a single-price condition (50 cents/drink), while a matched group was given a price reduction daily (25 cents/drink) during a three-hour pe ...200097717
in vitro analysis of allogeneic lymphocyte interaction. iv. dual recognition of b cell-associated mls locus and i-region determinants by a helper allogeneic effect factor (aef) generated across a minor h locus disparity.a helper allogeneic effect factor (aef) was produced across an incompatibility at the minor histocompatibility loci. this aef is genetically restricted in its activity since it helps b cells only of the stimulator haplotype and of haplotypes that share both an mls and i-region identity with the stimulator haplotype. the i-region genes involved here map to the i-a and/or i-c subregions. an anti-lym immunoadsorbent column but neither an anti-h-2 nor an anti-ia column absorbed aef helper activity. ...200087470
the production of hydroxyl radical by tallysomycin and copper(ii). 200087348
the nursing care and management of coronary artery grafts (revised). 200087189
[how reliable is ultrasound fetometry?]. 20002195807
improvement in iron status and liver function in patients with transfusional iron overload with long-term subcutaneous desferrioxamine.subcutaneous desferrioxamine (2--4 g over 12 h) was administered 6 nights each week to 34 patients with transfusional iron overloads who continued to receive regular blood-transfusions. all 34 patients showed a fall in serum-ferritin after 5 to 12 months. in some patients serum-ferritin fell almost to normal. liver function improved in all the patients, serum-aspartate-transaminase levels fell in all 17 patients tested, and liver-iron fell in 5 of 6 patients tested. these studies show that body- ...200087616
[prohibition of practice for dentists with unfavorable hepatitis b serology]. 2000101799
[effect of ionizing radiation on the development of plants and polyphenoloxidase activity]. 2000102010
[intraluminal diverticulum of the duodenum. report of a case and review of published cases].the intraluminal diverticulum of the duodenum is very rare; it is an anatomical sac like formation, located in the interior of the duodenum and communicating with it through an orifice situated a the upper pole of the diverticulum where the wall is covered by mucosa on both faces. it has interesting etiopathogenic problems. we present an observation after reviewing the corresponding literature. it was a 32-year old woman suffering from moderate epigastric pains, pyrosis, chronic constipation, ma ...200097140
prevention of burn injuries. 200094733
serum protein electrophoresis in healthy subjects and patients with liver disease. 2000101684
computers and automated technical procedures in blood transfusion laboratories. 200097760
[splenic hydatidosis]. 2000138881
[prevention of cardiovascular diseases]. 2000101793
levodopa boosts intellectual rating in senile dementia. 2000101689
[peruvian balsam and perfumes. studies on allergologic relations between these substances]. 20004847720
parkinson's disease.the classical clinical picture of parkinson's disease is all too frequently encountered in the elderly patient. the modern classification of causes of parkinson's disease lists 'idiopathic', and 'post-encephalitic forms', the latter being uncommon in this community.200016582
substance abuse: an understanding from psychoanalytic developmental and learning perspectives. 200097539
drug-induced lung disease.since there are no diagnostic studies to confirm the presence of a drug-induced lung reaction the physician will make a correct diagnosis only if he is aware of the drugs which have been identified to cause pulmonary reactions and their specific manifestations. failure to recognize a drug-induced lung disease can lead to significant morbidity and in some cases mortality. the major drug-induced lung diseases are reviewed, the drugs being presented in the context of their clinical use and the reac ...2000102005
[importance of close observation of the patient and confirmation of the findings]. 200097450
[general aspects of intravenous feeding of cancer patients].in order to obtain or maintain a good nutritional status in cancer patients, it is often necessary to perform intravenous nutrition. in summary, several studies have indicated that intravenous nutrition may be beneficial in association with surgery, radiation, or chemotherapy in patients with cancer. more controlled studies, however, are required. there is no indication at the present time of any adverse effects of this method of treatment in relation to tumor growth. the general nutritional imp ...2000101921
ocular manifestations of phycomycosis in a diabetic. 200097389
extra-anatomic bypass for treatment of leg ischemia. 20002195833
[improvement of blood viscosity after infusion of low-molecular hydroxyethyl starch (expafusin) in healthy subjects].in healthy volunteers, 500 ml of a 6% low molecular weight hydroxyethyl starch solution (expafusin) was infused intravenously within 30 minutes. blood samples for the measurement of rheological parameters were obtained before and after the infusion. blood and plasma viscosity were significantly decreased after the infusion of hes. red cell deformability as measured by a filtration technique was slightly improved. red cell aggregation as measured by a light transmission method was markedly reduce ...200094316
an erythrocyte membrane-protein anomaly in march haemoglobinuria.in three patients with march haemoglobinuria a well-defined protein abnormality has been revealed by high-resolution sodium-dodecyl-sulphate/polyacrylamide-gel electrophoresis.200091785
structural compartmentation of the cytosol: zones of exclusion, zones of adhesion, cytoskeletal and intercisternal elements. 200097812
[recommendations for the storage of serum absorbed on filter paper under rural conditions, for the diagnosis of chagas' infection with immunofluorescent test]. 200097768
deafness due to hypervitaminosis d. 200087663
interaction between lectin and liposomes containing gangliosides [proceedings]. 200094795
rhizosphere mycoflora of healthy and yellow vein mosaic virus infected okra (abelmoschus esculentus) plants.investigations on the rhizosphere mycoflora of healthy and virus (yvmv) infected okra plants showed a higher fungal population in the rhizosphere of healthy plants at preflowering and post-flowering stages than in that of diseased ones. maximum population was observed during flowering both in healthy and diseased plant rhizosphere as well as in non-rhizosphere soil. however, virus infected plants showed a higher population at the flowering stage than healthy ones. the quantitative differences in ...200094749
[intracavitary transillumination during surgery on the biliary system]. 2000101710
[the stability of metoclopramide solutions in glass and plastic containers. 32. problems of filling plastic containers with fluid drug preparations]. 200027824
national health insurance. 2000306602
neonatal tolerance: towards an immunogenetic definition of self. 200090008
[studies on cardiac principle in aconite roots. i. isolation and structural determination of higenamine (author's transl)]. 200034017
the typical dream: case studies. 20004347834
phencyclidine and ketamine intoxication: a study of four populations of recreational users. 2000101865
deep vein thrombosis. 200097405
visual averaged evoked responses in psychiatric patients. relationship to levels of 5-hydroxy-indoleacetic acid, homovanilic acid and tryptophan in cerebrospinal fluid. 200094355
the neurological manifestations of chronic inhalation of leaded gasoline.abnormal neurological signs were found in 46 of 50 children and adolescents chronically sniffing leaded gasoline. these abnormalities resolved within eight weeks in all but one case. exaggerated deep reflexes, postural tremor and evidence of cerebellar dysfunction occurred in a highly significnat number of patients. forty-nine had blood lead levels greater than or equal to 40ug/dl. the mean blood lead levels were significantly higher in those with (a) abnormally brisk deep reflexes and (b) with ...200097111
is serum total cholesterol outmoded? 200091908
unusual mlc responses of black patients with juvenile-onset diabetes. 199993814
qualitative alterations in plasma esterases in balb/c mice following the administration of diethylnitrosamine.selected non-specific plasma esterases in female balb/c mice, separated by polyacrylamide gel electrophoresis, were qualitatively altered following treatment of the mice with diethylnitrosamine (den). these alterations include a decreased preference for naphthyl butyrate as a substrate relative to naphthyl acetate; decreased sensitivity to enhancement by divalent cations such as ca2+, mg2+, and mn2; and an increased sensitivity to inhibition by eserine. all esterase species affected were also qu ...199996943
antral mucosal diaphragms in adults.a group of 53 patients with the diagnosis of antral mucosal diaphragm is reported. in over 50% of the cases the diaphragm was considered an asymptomatic lesion. in addition, an autopsy study in 29 unselected cases is reported with demonstration of five antral mucosal diaphragms in different forms. on the basis of these findings, it is evident that the antral mucosal diaphragm in the adult is not an acquired lesion secondary to peptic ulcer disease, but may be congenital. in addition, techniques ...1999116501
suction drainage after stripping of long saphenous veins. 199989589
epidermal cytoplasmic antigens. 199985677
to reuse or reconstruct: that is the question.with cost containment being a vital concern, health care facilities must carefully assess differences in the cost between new construction and renovation.1999103799
[hungarian-made titanium-polyamide knee joint prosthesis]. 199917789
estimating fat body mass from antrhopometric data.regression equations have been derived for the calculation of fat body mass in boys from 4 to 12 1/2 years old and girls 4 to 19 years old. height and weight give a good prediction of fat body mass, but the addition of skinfold thicknesses to the regression equations reduces the number of large errors in the estimates. the regression equations and the limits of accuracy are given.1999116536
differentiation of normal pressure hydrocephalus and cerebral atrophy by computed tomography and spinal infusion test.the diagnostic value of computed tomography (ct) and spinal infusion test (sit) was investigated in 27 patients with normal pressure hydrocephalus (nph) and 35 patients with cerebral atrophy. the most consistent ct finding of nph was dilatation of the temporal horns, that of cerebral atrophy widening of the convexity sulci. however, 43% of patients with cerebral atrophy demonstrated no cortical atrophy. the sit showed an excellent relation with isotope cisternography and continuous intracranial ...199993629
thyrotoxicosis during pregnancy.the diagnosis of thyrotoxicosis during pregnancy is difficult on clinical grounds only. the determination of free thyroid hormones or free thyroid hormone indices is important and is possibly supplemented by the trh stimulation test. thyrotoxicosis during pregnancy should always be treated actively. the authors recommend subtotal thyroidectomy if there are indications for surgical therapy (nodular goitre or large diffuse goitre). otherwise treatment with thyrostatic agents is used. after operati ...199984547
hyperthyroidism in juvenile diabetes mellitus.three cases of hyperthyroidism occurring in juvenile patients with diabetes mellitus are presented. the presence of hyperthyroidism should be suspected in patients with diabetes mellitus when goiters develop and when there is unexplained weight loss, tachycardia, tremors, unexplained increases in insulin requirement, or instability of the diabetes with a tendency toward development of ketosis and/or ketoacidosis.199996415
hurler/scheie phenotype. report of an inbred sibship with tapeto-retinal degeneration and electron-microscopie examination of the conjuctiva.an inbred sibship with corneal opacities and deficient alpha-l-iduronidase activity showed signs of a hurler/scheie phenotype. the children were of normal intelligence. in one of the children, electron microscopy of the conjunctiva showed membrane-bound intracellular vacuoles and the electroretinogram was extinguished. the consanguinity of the parents is taken to indicate the presence of homozygosity of a mutant gene different from both the hurler and scheie mutants, thus rejecting the concept o ...199996404
the unlabelled-peroxidase antiperoxidase method used for the localization of leghaemoglobin in glycine max nodules [proceedings]. 199993466
schwartz-jampel syndrome: i. clinical, electromyographic, and histologic studies.in a new, typical case of schwartz-jampel syndrome (sjs) the origin of the disorder was found to be purely myogenic. concentric needle emg showed abundant and persistent spontaneous activity, maximal at insertion, and uninfluenced by local curarization. single-fiber emg showed rather stable, sometimes intermittent, discharge series with occasional amplitude and/or frequency fluctuations. it could be demonstrated that this activity did not consist of complex repetitive discharges, but of independ ...19992366824
[letter: lymphocytotoxicity test using chromium 51. use of monolayer cell cultures as nonspecific target cells]. 19991129078
[effect of bromocriptine on the "prolactin-like cell" of nectophrynoides occidentalis (amphibia, viviparous anura): optical and electronic microscopical studies].bromocriptin has an effect on prolactin-like cells of nectophrynoïdes occidentalis. 16 days after delivery, these cells are fully active in normal animals. retention of secretory granules and myelinic formations have been observed in the prolactin-like cells of females treated by cb 154.199997001
[effect on macrophages of acute stress induced in mice by local irradiation].in examining the role of radiation in inducing immunosuppression in tumor-bearing mice it has been shown that the experimental acute stress inadvertently generated by the procedure is profoundly immunosuppressive. it would appear that monocytes under the influence of glucocorticoïds are sequestered in the spleen. this monocyte immobilisation leads to rapid suppression of local inflammatory reactions including delayed hypersensitivity. the increased number of marcrophages in the spleen is co-inci ...199996964
a double-blind trial of synthetic salmon calcitonin in the treatment of acute pancreatitis.a multicenter randomized double-blind trial on the use of synthetic salmon calcitonin (sct) was carried out in 94 patients with acute pancreatitis. in addition to strict standard treatment--without aprotinin, atropine, or antacids--50 patients received daily 3 x 20 micrograms = 300 mrcu sct intravenously and 44 patients received placebo for 6 days. mortality rate was not influenced, overall mortality being 5.3%. the number of patients without pain and with normalized serum amylase on a given day ...199994176
vitamins in intravenous feeding: a study of water-soluble vitamins and folate in critically ill patients receiving intravenous nutrition.red cell b vitamins, folate and white cell vitamin c were measured in a group of critically ill surgical patients before and following a course of intravenous nutrition. patients received a widely used vitamin supplementation regimen in the form of one ampoule of water-soluble vitamins daily and recommended doses of intramuscular folate, vitamin b12 and vitamin k weekly. this regimen was adequate to maintain tissue levels of the water-soluble vitamins and folate. patients with initially low valu ...199996904
sugar binding properties of various metal ion induced conformations in concanavalin a.concanavalin a is known to undergo a first-order conformational transition when metals are added to the demetallized protein at ph 5.6 (brown, r.d., iii, et al. (1977) biochemistry 16, 3883--3896). the rate constants for this process, which wer have measured using a polarographic technique, are identical when zinc, cobalt, or manganese occupies s1 and calcium occupies s2. the reducible sugar, p-nitrophenyl alpha-d-mannopyranoside, binds only to the locked conformational structure which is formed ...199996852
effects of x-rays on the chloroplasts of acetabularia mediterranea [proceedings]. 199993929
pattern reversal evoked cortical responses in normals. a study of different methods of stimulation and potential reproducibility.using a commercially available television set for stimulation of 78 healthy subjects, the upper limit of normal for the latency of the major positive wave (p 100) of checkerboard pattern reversal evoked potentials is practically the same as that obtained by employing slide projector combined with a rotating mirror. potentials evoked by a small pattern, for purely foveal stimulation, were often difficult to evaluate exactly. fixation of a large pattern at the upper border of the stimulus field br ...199993635
radiotherapy in marginal resectable and non-resectable rectum cancer.66 patients with inoperable rectum cancer were treated with megavoltage irradiation. these patients were studied in order to see if high dose radiotherapy could cure inoperable patients. no patients were cured. the palliative effect was important, because in most patients a colostomy was avoided. 21 patients with marginal resectable rectum cancer received preoperative irradiation. the effect of combined therapy in this highly selected group of patients gives an indication for a 50% 5-year cure r ...199996483
inosine analogs as substrates for adenosine kinase--influence of ionization of the n-1 proton on the rate of phosphorylation. 199923125
time course of adh-induced intramembranous particle aggregation in toad urinary bladder. 199996700
[a new trial to progressed cancer of the pancreas with intraoperative radiotherapy (author's transl)]. 1999115952
[induction of sister chromatid exchanges in vivo in bone marrow cells of akr mice].induction of sister chromatid exchanges (sces) in bone-marrow cells of akr mice receiving in vivo four drugs well-known for their mutagenesis activity has been tested. a decreasing activity in sce was shown by the drugs tested in the order cyclophosphamide, procarbazine, methylmethane sulfonate and diethylnitrosamine. this technique presents an encouraging method for testing the effect of chemical agents in vivo.199996954
[associated congenital pulmonary stenosis and aortic stenosis. apropos of 5 cases]. 199996770
diffuse cutaneous mastocytosis: a report of neonatal onset.a child developed diffuse cutaneous mastocytosis when 20 days old. his prognosis appears good, compared with other reports of similar neonatal onset.199994218
[renewal of noradrenaline in different zones of the central nervous system of inbred mice strains and their recombinants].a good correlation exists between the learning capacity and norepinephrine metabolism in the neocortex of c57 and balb inbred mice strains, as well as their f1 hybrids and seven recombinant inbred strains derived from their cross. the animals with a better learning performance are characterised by low levels of norepinephrine, as well as a slow metabolic rate of this neurotransmitter in the cortex. such a correlation has not been found to exist in the other cerebral regions studied.199996976
group systems of serum proteins and erythrocyte enzymes in malignant lymphoma.four group systems of serum proteins (hp, gc, gm, km) and five group systems of erythrocyte enzymes (ap, pgm1, gpt, ak, esd) were determined in 63 patients with malignant lymphoma. statistical analysis of the distribution of the above mentioned systems in patients and polish population samples did not reveal any significant differences, which points to the lack of any correlation between the disease and the group systems under examination.199985572
fine-needle aspiration cytology. 199989365
[prospective etiologic survey on apparently primary nonobstructive myocardiopathies in adults. 57 cases, excluding ischemic cardiopathies].a prospective study into the aetiology of presumed primary non-obstructive cardiomyopathy was carried out in 57 patients who had no lesions of the trunk of the coronary artery; one case of haemochromatosis and one of amyloidosis were found. excluding these two cases of cardiomyopathy which were in fact secondary, most of the others were associated with manifestations or with complications of myocardial diseases (two pulmonary emboli and one case of jaundice) or pathology associated with it. inve ...199996761
noninvasive determination of labeling index for dna synthesis in epidermoid carcinomas of head and neck. 1999395703
[profile of cefmetazole. report iii. in the field of internal medicine (author's transl)]. 1999115938
tetanus neonatorum treated by a single high dose of a.t.s. subcutaneously around umbilicus.thirteen cases of neonatal tetanus were treated conservatively between 1976 and 1977. a single dose of a.t.s. was infiltrated subcutaneously around the umbilicus and sedation and antibiotics were given as required along with special nursing care. in a previous study (rathore 1976) large amounts of a.t.s. were given in divided doses by both intravenous and intramuscular routes, the mortality rate was 74 per cent, while in the present series the mortality was reduced to 30.7 per cent.199996285
determination of the quaternary structure of alpha-d-mannosidase from medicago sativa l. [proceedings]. 199993904
synthesis, characterization and antimicrobial activity of d metal complexes of some 2-substituted-1h-benzimidazoles.the metal complexes of nine 2-substituted-1h-benzimidazoles (i-ix) with ni(ii), pd(ii), cu(ii), ag(i), zn(ii) salts were synthesized. the compounds were characterized by melting point, analytical data, ir spectroscopy and magnetic susceptibility. the antimicrobial activity of the compounds was determined by the disk diffusion method in mueller-hinton agar on staphylococcus aureusatcc 6538, staphylococcus epidermidis atcc 12228, escherichia coli atcc 8739, klebsiella pneumoniae atcc 4352, pseudom ...199918472907
[value and limit of photocoagulation for juxtafoveolar sub-retinal vessels (author's transl)].sub-retinal new vessels arising from the choroid are the most dangerous components in disciform maculopathies. the greatest advance made in their treatment has been due to the use of photocoagulation over the last few years, but their destruction by this method is still a very controversial subject. the aim of the present study was to define which lesions should be treated and which should not. results demonstrated that the use of photocoagulation to destroy new vascular membrane which is very c ...199994069
some response characteristics of co2 electrodes.radiometer carbon dioxide electrodes and probably other electrodes of similar design do not give the same readings, except under certain very limited conditions, when used to measure carbon dioxide concentrations in solution and the gas phase with which the liquid is in equilibrium. blood samples of high p(co2), when introduced into the sample chamber of an electrode at low p(co2), lose co2 to the electrode resulting in a reduction of sample p(co2) and hence, because the sample size is very smal ...199996504
molecular perspectives of monovalent cation selective transmembrane channels. 199994042
recent developments in diabetes research. 199997046
[automated information system as a method of studying and preventing morbidity among workers in the petroleum industry]. 19992151192
[contribution of divalent cations to the maintenance of membrane potentials in the oocytes of pleurodeles waltlii michah (amphibia, urodela)].when the external concentration of ca and mg is changed, the oocyte membrane potential, in the urodela amphibian: pleurodeles waltlii, is not significantly modified. the addition of chelator agents, egta and edta in ca, mg free steinberg solution promotes a membrane depolarisation and the rise of membrane conductance. it is concluded that divalent ions ca++ and mg++ are needed to maintain a potential difference between internal and external medium of the oocyte.199996993
[ph-potentiometric study of 1-isadrine, 1-teranole and related compounds]. 199918365
dynamics of correlated genetic systems. iv. multilocus effects of ethanol stress environments.four replicate populations of drosophila melanogaster, two reared on medium supplemented with ethanol and two reared on standard medium, were electrophoretically monitored for 28 generations. during the first 12 generations, allelic, genotypic and gametic frequencies were determined for eight polymorphic enzymes: got, alpha-gpdh, mdh, adh, to, e6, ec and odh. samples from generation 18 and 28 were electrophoretically typed for adh and alpha-gpdh. in addition, samples from generation 27 were anal ...1999103779
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