Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| the distribution of melanin in the developing optic cup and stalk and its relation to cellular degeneration. | the early distribution of melanin in the developing optic cup and stalk and its relationship to cellular degeneration have been studied during intrauterine development in hamsters, mice, ferrets, and humans. the extensive degenerative changes that occur in the region of the optic fissure do not involve any pigment-bearing cells. melanin is not formed at the site of the fissure until after the processes of fusion and the associated degenerative changes are complete. in contrast to this, there is ... | 1981 | 7310485 |
| persistent oestrus in ferrets. | 1981 | 7197427 | |
| aplastic anemia associated with estrus in pet ferrets. | aplastic anemia in association with estrus was diagnosed in 6 pet ferrets. the ferrets had been examined because of anorexia, depression, and lethargy of 2-5 days' duration. consistent clinical findings were pale mucous membranes and enlargement of the vulva. hemorrhages were found in 3 ferrets. hematologic findings included severe anemia, thrombocytopenia, granulocytopenia, and hypocellularity of the bone marrow. the aplastic anemia was attributed to prolonged estrogenic exposure in ferrets wit ... | 1981 | 7196908 |
| increasing dosages of estradiol benzoate activate equivalent degrees of sexual receptivity in gonadectomized male and female ferrets. | 1981 | 7267767 | |
| [hematological and clinical biochemical parameters in ferrets under various physiological and pathological conditions. 1. comparative studies of changes in the hemograms of pregnant, lactating and nonpregnant females]. | 1981 | 7347485 | |
| zinc poisoning in ferrets (mustella putoris furo). | 1981 | 7265896 | |
| adrenergic and cholinergic nerves mediate fluid secretion from tracheal glands of ferrets. | our aim was to determine whether adrenergic as well as cholinergic nerves mediate secretion of fluids from tracheal submucosal glands and, if so, via which receptors. to do this, we studied the secretory responses of tracheal segments to electrical and pharmacologic stimulation in vitro in the presence and absence of a specific nerve blocker and autonomic antagonists. stimulation caused small elevations, or "hillocks," the size of which we estimated by measuring their diameters. we found that el ... | 1980 | 7440290 |
| foraging cost and meal patterns in ferrets. | 1980 | 7413810 | |
| [morphology and biochemistry of blood of various mustelids. 4. determination of various metabolites in the arterial plasma of mink--principles of the preparation of standard values for laboratory diagnosis in farm mink (mustela vison schreber, 1777)]. | an account is first given of latest knowledge on how to determine clinico-diagnostic applicability of certain metabolites in mink plasma and serum. then, statistically treated results obtained from analysis of levels of total protein, albumin, creatinine, urea, total cholesterin, triglyceride, and total bilirubin are tabulated and discussed, with due consideration being given to sexual dimorphism, following determination of those values from arterial plasma of 118 male and 124 female minks, aged ... | 1980 | 7212937 |
| [morphology and biochemistry of blood of various mustelids. 3. enzymographic studies of arterial plasma of mink (mustela vison schreber, 1777)]. | twelve different enzyme activities, which are listed and explained in greater detail in table 2, were determined statistically secured, and discussed, following a three-year study into arterial plasma of 118 female and 124 male minks, aged between six and seven months and kept under anaesthesia. simply normally distributed or logarithmically distributed plasma enzyme activities were found to differ primarily by sex, with other experimental conditions being identical and regular. the enzyme activ ... | 1980 | 7011244 |
| an apparatus for the preparation of cavities in the canine teeth of ferrets. | an apparatus is described for the preparation of standardized cavities in the canine teeth of ferrets. one hundred cavities were cut, and there was highly significant correlation between the distance the bur was advanced (machine depth) and the cavity depth in dentine. it was possible to cut cavities predictively with small and large residual dentine thicknesses. the method described was not damaging to the pulp. | 1980 | 6928439 |
| polychlorinated biphenyls (aroclors 1016 and 1242): effects on survival and reproduction in mink and ferrets. | diets that contained various levels of supplemental aroclor 1242 or aroclor 1016 were fed to mink and ferrets to investigate the chronic toxicity of these pcbs in two closely related species. in mink, aroclor 1242 was found to be more toxic than comparable or higher levels of aroclor 1016. the aroclor 1242 diets caused complete reproductive failure at levels as low as five ppm of the diet. aroclor 1016 impaired reproduction less than aroclor 1242. although fewer females whelped and the four-week ... | 1980 | 6776911 |
| experimental models for study of common respiratory viruses. | numerous epidemiological studies have shown that there is excess respiratory disease morbidity in areas of high atmospheric pollution, implying an interactive effect on the clinical illness associated with these common infections. the principal etiologic agents of human respiratory infections are respiratory syncytial virus (rsv), influenza viruses (iv), parainfluenza virus types 1 and 3 (p1, p3), adenoviruses (ad), rhinoviruses (rv) and mycoplasma pneumoniae (mpn). understanding the pathogenesi ... | 1980 | 6250807 |
| isolation of a paramyxovirus from the cerebrospinal fluid of a dog with posterior paresis. | a paramyxovirus was isolated from cerebrospinal fluid of a dog with a history of incoordination and posterior paresis. the virus apparently was not related to canine distemper virus (cdv), considering the lack of virus neutralization with cdv-specific antibody, negative immunofluorescence with cdv-specific conjugate, and avirulence for ferrets. the virus was antigenically related to a prototype strain of canine parainfluenza virus, as determined by positive immunofluorescence with canine parainf ... | 1980 | 6254938 |
| survey of virally mediated permeability changes. | 1. sendai virus causes permeability changes when added to freshly isolated brain cells (cerebellum or ependymal cells) or to a culture of forebrain cells. 2. sendai virus causes permeability changes when added to organ cultures of ferret lung or nasal turbinate. influenza virus causes no permeability changes under these conditions. 3. rabies virus and vesicular-stomatitis virus, in contrast with sendai virus, do not cause permeability changes in bhk cells or lettrée cells. 4. serum from patients ... | 1980 | 6258574 |
| adherence of pseudomonas aeruginosa to tracheal cells injured by influenza infection or by endotracheal intubation. | adherence of pseudomonas aeruginosa to normal, injured, and regenerating tracheal mucosa was examined by scanning electron microscopy. uninfected and influenza-infected murine tracheas were exposed to six strains of p. aeruginosa isolated from human sources and one strain of platn origin. all of the strains tested adhered to desquamating cells of the infected tracheas, but not to normal mucosa, the basal cell layer, or the regenerating epithelium. adherence increased when the incubation time of ... | 1980 | 6769805 |
| absence of m protein in a cell-associated subacute sclerosing panencephalitis virus. | measles virus has been suggested to cause subacute sclerosing panencephalitis (sspe), a slow central nervous system disease of children. however, several questions remain about the pathogenesis of sspe. for example, it is not known whether alteration of the measles virus genome has a role in the initiation and persistence of the disease. several studies have compared the rna and protein composition of wild-type (wt) and sspe strains of measles virus in a search for markers characteristic of the ... | 1980 | 6772958 |
| oestrogen production by blastocyst and early embryonic tissue of various species. | oestrogen synthesis by the early embryo in vitro was studied with tissue from pigs, sheep, cows, roe deer, ferrets, cats, rabbits and a plains viscacha. definitive evidence for aromatase activity and oestrogen synthesis in preimplantation trophoblast was obtained for the pig with the formation of oestrone, oestradiol-17 beta and oestradiol-17 alpha from 3h-labelled androstenedione and dehydroepiandrosterone. aromatase activity was appreciably lower in all other species studied, and labelled oest ... | 1980 | 6448924 |
| suppression of maturation of dirofilaria immitis in mustela putorius furo by single dose of ivermectin. | 1980 | 6893467 | |
| the effect of immunes on the spread of distemper in small ferret populations. | 1980 | 7189705 | |
| unlike rats, ferrets do kill under antidepressants. | 1980 | 7190226 | |
| the spontaneous discharge in abdominal vagal efferents in the dog and ferret. | this study demonstrates by collision that vagal efferent fibres project from the dorsal medulla to the intra-abdominal organs in the dog and ferret. the efferents had a low frequency (below 5 hz) spontaneous discharge with the majority having a unimodal distribution of interspike intervals. this background level of activity is sufficient to account for the basal levels of secretion and motility observed during the interdigestive period. | 1980 | 7191105 |
| ultrastructure of the nonciliated bronchiolar epithelial (clara) cell of mammalian lung. iii. a study of man with comparison of 15 mammalian species. | two morphologic characteristics have been used to define the nonciliated bronchiolar epithelial cell: (1) abundance of agranular endoplasmic reticulum (aer) and (2) numerous membrane-bound ovoid granules. in this study, we examined lobectomy specimens from three nonsmoking humans: one male (9.5 yr) and two females (62 and 43 yr) for comparison with lung specimens from mammalian species used as experimental models in lung research. following fixation by airway infusion at constant pressure (20 cm ... | 1980 | 7227344 |
| heterotypic immunity to influenza in ferrets. | heterotypic immunity to influenza virus in ferrets operated against heterotypic influenza viruses but not heterologous viruses. contrary to prior reports, the protection conferred lasted for at least 18 months. this type of immunity limited virus shedding but did not prevent infection. these results suggest that this phenomenon could play a role in determining the severity of infections caused by type a influenza viruses in humans. | 1980 | 7216432 |
| metastatic, papillary cystadenocarcinoma of the mammary gland in a black-footed ferret. | a simple, papillary cystic adenocarcinoma of the mammary gland with metastases to the internal iliac and mesenteric lymph nodes, liver, and spleen was observed in a 12 to 13 year old female black-footed ferret (mustela nigripes). histologically, the tumor was aggressive, and lymphatic invasion was found. attempts at virus isolation were negative. other findings were bilateral infarcts in the kidneys, apparently resulting in acute renal shutdown and death, multiple thrombi in the right atrium, ao ... | 1980 | 7463613 |
| salicylate-induced teratogenesis in the ferret. | 1980 | 7464451 | |
| vagal afferent discharge from mechanoreceptors in different regions of the ferret stomach. | 1. the rate and volume of gastric filling was estimated in conscious ferrets by measuring the amount of milk they would drink after an overnight fast. the mean volume was 94.5 +/- 7.5 ml. at a rate of 13.0 +/- 0.74 ml./min. an intragastric infusion rate of 10 ml./min to a total of 50 ml. was selected as a standard distension stimulus. 2. action potentials were recorded from single gastric afferent fibres in the cervical vagus. all but two of thirty-six afferent units were tonically active when t ... | 1980 | 7359436 |
| reflex excitation of antral motility induced by gastric distension in the ferret. | 1. in the urethane anaesthetized ferret gastric inflation with 50 ml. 0.9% nacl at a rate of 10 ml./min evoked large gastric contractions. the threshold of intragastric pressure required to elicit the reflex was 3.1 +/- 0.5 cmh2o. 2. the response was enhanced by splanchnic nerve section and markedly reduced by bilateral cervical vagotomy, indicating that both afferent and efferent limbs of the reflex were in the vagus nerves. 3. by using a transected stomach it was shown that distension of the c ... | 1980 | 7359444 |
| simple technique for bleeding ferrets (mustela putorius furo). | 3-5 ml of blood can be obtained routinely from the tail of a conscious ferret without affecting the wellbeing of the animal. the development of this technique makes the ferret more readily available as an alternative species for multidose toxicity studies. | 1980 | 7359890 |
| experimental infection of hedgehog, hamsters, rabbits and ferrets with the virus lednice. | 1980 | 7364349 | |
| aspects of virulence in ferrets exhibited by influenza virus recombinants of known genetic constitution. | 1980 | 7365283 | |
| the age dependence of respiratory syncytial virus growth in ferret lung can be shown in organ and monolayer cultures. | 1980 | 7371226 | |
| aromatase activity in corpora lutea of the ferret. | 1980 | 7388106 | |
| a scanning electron microscopic study of the atrioventricular bundle of the ferret. | scanning electron microscopy was used to examine the three-dimensional morphology of atrioventricular (av) bundle cells in the ferret heart. these cells are organized into fascicles with extensive intercellular contact between cells within a fascicle and less contact between cells of different fascicles. the cell surface shows conspicuous ridges and depressions, as well as smooth regions. the distribution of myofibrils within an av bundle cell is not uniform. mitochondria of these cells are oval ... | 1980 | 7388892 |
| the metabolic n-oxidation of 3-substituted pyridines in various animal species in vivo. | the intraperitoneal administration of pyridine, 3-methylpyridine and 3-chloropyridine to mice, hamsters, rats, guinea-pigs, rabbits and ferrets, resulted in the urinary excretion of their n-oxides. pyridine-n-oxide was found to be a quantitatively important metabolite of pyridine in all the species studied; the percentage of the dose excreted in the urine as pyridine-n-oxide ranged from 10% in rats to about 40% in mice and guinea-pigs. 3-chloropyridine-n-oxide and 3-methylpyridine-n-oxide accoun ... | 1980 | 7389753 |
| angiotensin, hypoxia, verapamil and pulmonary vessels. | 1. the action of angiotensin ii on lung vessels was compared in dogs, cats, ferrets and rats using isolated perfused lungs and lobes of lungs perfused in vivo, both at constant flow, so that increases in inflow pressure at constant outflow pressure indicated increases in resistance. 2. angiotensin ii caused some increases in resistance in dogs, cats and rats but not ferrets. the increases were small compared with changes in the systemic circulation. larger increases could be obtained in isolated ... | 1980 | 7398135 |
| smooth-muscle hyperplasia and neoplasia in the ovaries of domestic ferrets (mustela putorius furo). | twenty cases of ovarian leiomyoma in a colony of ferrets are described. the tumour appears to be relatively frequent in this species which is in general noted for its lack of susceptibility to spontaneous and induced neoplasia. | 1980 | 7400878 |
| neutral carrier ion-selective microelectrodes for measurement of intracellular free calcium. | this paper describes the making and testing of calcium-selective microelectrodes for measurement of intracellular [free ca2+] levels. pipettes of tip outer diameter down to 0.4 micron were siliconized by a novel and easy method of vapor treatment. the tips were filled with a sensor mixture using the neutral ligand and solvent of oehme et al. (oehme, m., kessler, m. and simon, w. (1976) chimia (aarau) 30, 204-206) but with very hydrophobic cations replacing na+ in the salt component. this change ... | 1980 | 7407109 |
| the gastric motility patterns induced by direct and reflex excitation of the vagus nerves in the anaesthetized ferret. | 1. under urethane anaesthesia the ferret has a stomach which exhibited spontaneous contractions. the amplitude of the contractions was reduced, but never abolished, by vagotomy, atropine or hexamethonium. 2. electrical stimulation of the cut peripheral end of the cervical or abdominal vagus nerves activated both excitatory and inhibitory fibres, whereas reflex activation by stomach distension or by cytoglucopenia was predominantly excitatory on gastric motility. the magnitude of the response to ... | 1980 | 7411457 |
| studies of influenza virus infection in newborn ferrets. | influenza virus infection by the intranasal route was found to be invariably fatal in newborn ferrets. some obviously died of influenza pneumonia; others died of aspiration pneumonia or showed only minimal or non-specific changes in the lungs. all, however, had severe lesions in the upper respiratory tract, and it is suggested that obstruction of airways and oesophageal passages, in combination with feeding difficulties, played a major role in causing death. the relevance of the findings to the ... | 1980 | 7431374 |
| [use of monoclonal antibodies for the antigenic analysis of the hemagglutinin of influenza viruses (h3n2) isolated in the ussr in 1979-1980]. | monoclonal antibodies for the a/england/864/75 strain hemagglutinin were used for antigenic analysis of influenza a (h3n2) viruses isolated in the ussr in december 1979--january 1980. the results of studies with 5 different monoclones were compared with those obtained with postinfection ferret sera. it was shown that several variants of epidemic strain could circulate during one epidemic season. the epidemic in the ussr in december, 1979--january 1980 was caused by influenza viruses h3n2 similar ... | 1980 | 7434736 |
| peripheral functional organisation of vagally evoked gastric motor responses in the ferret. | the aims of the present study were to determine the relative amplitudes of intragastric motor responses evoked by different vagal branches and to establish whether the effects of acute or chronic vagotomy could be predicted from these data. intragastric pressure responses to electrical stimulation of the vagus were measured in urethane-anaesthetised ferrets and acute or chronic vagotomies were performed. the results show that the left and right cervical vagi were equipotential and fully overlape ... | 1980 | 7439800 |
| a scanning electron microscopic study of the ferret atrioventricular node. | the atrioventricular (av) node and surrounding transitional zone in the ferret heart were examined with scanning electron microscopy. this permitted the direct visualization of the three-dimensional cell shape, as well as intercellular relationships. transitional cells were roughly cylindrical with extensively branching end processes. these cells were apposed to many adjacent transitional cells. the superficial av nodal cells were smaller than transitional cells and were fusiform in shape. most ... | 1980 | 7446436 |
| development of ferret limb buds in organ culture. | the forelimb bud explants from ferret embryos at days 20, 21, 22, 23 and 24 of gestation were cultured in a trowell organ culture system. satisfactory differentiation of the limb bud skeleton was achieved with limbs from embryos explanted at 22 days of gestation (up to 50 somites). limb buds explanted at 20 and 21 days had poorly differentiated distal segments while those explanted at 23 and 24 days of pregnancy provided less information because chondrogenesis was already under way at the beginn ... | 1980 | 7462101 |
| the role of the vagus and splanchnic nerves in the regulation of intragastric pressure in the ferret. | 1. the role of the vagus and splanchnic nerves in the regulation of intragastric pressure was investigated by quantifying the effect of nerve section on the response to a standard fluid inflation of the stomach. an opportunity was also taken to compare the responses to a step and physiological ramp inflation of the same volume (50 ml). 2. the peak pressure at the end ot the step inflation (13.6 +/- 1.0 cmh2o) was twice that for a ramp inflation (6.2 +/- 0.4 cmh2o). 5 min after the peak the press ... | 1980 | 7205670 |
| immunolabeling of sspe and wild-type measles viruses in ferret brain cell culture. | immunocytochemical studies using horseradish peroxidase labeled antibody were undertaken in an attempt to determine whether there are detectable antigenic differences which correlate with the biological properties of differences which correlate with the biological properties of different strains of sspe and wild-type measles virus grown in ferret bran cell cultures. the rabbit anti-measles hyperimmune serum used in this experiment contained antibodies to all the measles virus proteins when teste ... | 1980 | 6998252 |
| [evidence of canine distemper virus in kidneys of apparently healthy ferrets (author's transl)]. | 1980 | 7006506 | |
| manual restraint of the ferret. | 1980 | 6900463 | |
| pulpal response to a temporary crown and bridge material in ferret teeth. | the histological effects of a temporary crown and bridge material (scutan) on the pulp of canine teeth of ferrets was investigated at time intervals up to 6 months. after 24 h a moderate to severe pulpal response was observed which persisted up to 6 months. a case of contact sensitivity to scutan is reported. | 1980 | 6936520 |
| the effects of sodium carbenoxolone on the stability of cellular membranes. | various mechanisms have been proposed for the mode of action of carbenoxolone, most of which contribute to improving the mucosal defence and the protective mucus barrier. the incorporation of many sugars into the glycoprotein fraction of gastric mucus of man, ferret and rat is increased by carbenoxolone and the turnover of gastric epithelial cells in the mouse has been shown to decrease after carbenoxolone treatment. the gastric mucosal cell membrane together with the subcellular endoplasmic ret ... | 1980 | 6937938 |
| excretion of monovalent ions and water in the saliva of the ferret. | 1980 | 6941999 | |
| zinc toxicity in the ferret. | 1980 | 6974744 | |
| relation between transmucosal potential difference, ionic flux, and the intraluminal supply of h+ in the ferret stomach. | to investigate the relation between gastric transmucosal potential difference, ionic flux, and the intraluminal concentration of h+, test solutions containing various concentrations of hcl were instilled into ferret stomachs both before and after exposure to various doses of acetic acid. the changes in ionic composition of the test solution were determined and the transmucosal potential difference was recorded throughout each experiment. the results showed that after exposure to the organic acid ... | 1979 | 36767 |
| immunological studies of subacute measles encephalitis in ferrets: similarities to human subacute sclerosing panencephalitis. | ferrets inoculated with subacute sclerosing panencephalitis virus strains d.r. and biken developed a subacute encephalitis. brain extracts, at neutral ph, from these ferrets showed high measles antibody titers, increased concentrations of immunoglobulin g (igg), and higher igg/albumin ratios than those of controls. although the brain extracts of subacute encephalitic animals showed significant synthesis of measles-specific igg (20 to 60% of the total igg) within the central nervous system, the e ... | 1979 | 39084 |
| further studies of the antigenic properties of h3n2 strains of influenza a isolated from swine in south east asia. | h3n2 strains of influenza a isolated from swine in hong kong were compared with human strains of h3n2 influenza a variants in reciprocal hi tests using ferret sera. one isolate from swine was indistinguishable from a/hong kong/68, one set of viruses isolated in 1976 and 1977 was most related to a/hong kong/68 but was not identical to it, two isolates from 1976 were 'bridging strains' that cross-reacted equally with the contemporary variants a/victoria/3/75 and a/texas/1/77, similarly to a small ... | 1979 | 91663 |
| histology and mucosubstance histochemistry of ferret lingual glands. | the histology and mucosubstance histochemistry of the ferret lingual glands were studied. both serous and mucous minor salivary glands were present in the posterior part of the tongue. in serous glands, acinar cells and a very few cells of the excretory ducts contained granules which gave reactions for neutral mucopolysaccharides only. the mucous glands, including the duct system, contained mainly weakly sulphated acidic mucin, some neutral mucin but no carboxylated mucin. occasional goblet cell ... | 1979 | 93387 |
| effects of d-amphetamine, maprotiline, l-dopa, and haloperidol on the components of the predatory behavior of the ferret, putorius furo l. | ferret predation on rats was examined in an arena. one hour before the test one of the following drugs was administered. d-amphetamine (0.8 and 1.4 mg/kg im), maprotiline (10 and 40 mg/kg orally), l-dopa (30 and 60 mg/kg orally), or haloperidol (0.14 and 0.6 mg/kg im). provided that capture was successful, the sequence of the behavioral components was not changed by these drugs. with the exceptions of paw movements and rolling over, which were not affected by the drugs, the components of predato ... | 1979 | 116280 |
| the induction of hepatic and extrahepatic xenobiotic metabolism in the rat and ferret by a polychlorinated biphenyl mixture (aroclor 1254). | 1. the effect of a single i.p. dose (500 mg/kg) of a polychlorinated biphenyl mixture (aroclor 1254) on hepatic and extrahepatic xenobiotic metabolism in male rat, and male and female ferret, was studied. 2. aroclor 1254 treatment induced hepatic microsomal n-demethylase activities, and cytochrome p-450 and protein content in both rat and ferret. liver size and aniline 4-hydroxylase were also increased in rat, but not ferret. the polychlorinated biphenyl mixture appeared to be a mixed-type induc ... | 1979 | 119357 |
| differentiation of coital behavior in mammals: a comparative analysis. | the evidence reviewed suggests that in all mammalian species the adult male's ability to display masculine coital behavior depends in part on exposure of the developing brain to testicular testosterone or its metabolites. in many mammals, particularly rodents, ruminants, and some carnivores, perinatal exposure to androgen also causes behavioral defeminization, i.e., reduced capacity to display typically feminine coital behavior in response to gonadal hormones in adulthood. the data reviewed sugg ... | 1979 | 120519 |
| [the ferret (putorius putorius furo), an additional final host of sarcocystis muris (author's transl)]. | two ferrets were fed mice experimentally infected with sarcocystis muris. after 7 days they excreted with their faeces for 9 days sporocysts which were morphologically indistinguishable from s. muris sporocysts. five mice which each received 70 of these sporocysts orally developed macroscopically visible cysts of s. muris in their musculature after 4 months. | 1979 | 107667 |
| live influenza vaccine: screening of attenuated virus strains by a 50% ciliary activity inhibition test in organ cultures of ferret trachea. | this study of three live attenuated inhibitor-resistant influenza vaccines showed that these preparations are usually antigenic and that they caused no significant reactions when characterized by an index of attenuation equal to or slightly better than 1.0 arbitrarily attributed to the 'reference' attenuated a/hong kong/68 strain of beare and bynoe. this index, measured in vitro on ferret tracheal rings, is expressed as the ratio of the time required for ciliary activity inhibition of 50% of the ... | 1979 | 378337 |
| comparison of sevral wild-type influenza viruses in the ferret tracheal organ culture system. | several strains of wild-type influenza a virus were studied in the ferret tracheal organ culture system. ciliary activity and viral replication were measured. ciliary activity was reduced more rapidly by a/hong kong/45/68 (h3n2) (a/hk) and a/victoria/3/75 (h3n2) (a/vic) than by a/new jersey/8/76 (hsw1n1) (a/nj), a/scotland/840/74(3hn2) (a/scot), or a/ussr/90/77 (h1n1) (a/ussr). a/hk, a/vic, and a/scot produced titers of virus higher than a/ussr or a/nj during the first three days after infection ... | 1979 | 399387 |
| sulfhydryl-mediated depression of ciliary activity: an adverse effect of acetylcysteine. | although n-acetyl-l-cysteine (mucomyst) is an effective mycolytic, numerous investigations have failed to demonstrate a consistent improvement in pulmonary mechanics following its use. in order to determine whether its beneficial mucolytic activity might be counterbalanced by a deleterious direct effect on cilia, we studied its effect on the activity of ciliated epithelium in the ferret tracheal organ culture system. n-acetyl-l-cysteine consistently caused progressive time-dependent ciliostasis ... | 1979 | 429865 |
| the atrioventricular node and bundle in the ferret heart: a light and quantitative electron microscopic study. | the cells of the atrioventricular (av) junction in the ferret heart were examined using light microscopy, a wax-model reconstruction and quantitative electron microscopy to determine their organization and characteristics. a series of subdivisions of the specialized tissues of the av junction was apparent at both the light and electron microscopic levels. a transitional zone was observed interposed between the atrial muscle cells and the av node. the av node consisted of a coronary sinus portion ... | 1979 | 433788 |
| [adpatibility of 2 rabies virus strains isolated in middle europe to a domestic and 2 wild species. a contribution to the epidemiology of rabies. 4. transmission studies in ferrets with a rodent isolate]. | 1979 | 442882 | |
| brugia pahangi and dirofilaria immitis: experimental infections in the ferret, mustela putorius furo. | 1979 | 446585 | |
| immunoprophylaxis of respiratory syncytial virus infection in the infant ferret. | infant ferrets can be protected from respiratory syncytical virus challenge at 3 days of age by gestational infection of their mothers. ferrets acquire their immunity to respiratory syncytial virus postpartum via immunizing products of lactation. the level of protection against viral replication correlates with the maternal serum neutralizing titer or a concomitant factor. passive administration of adult ferret serum with a neutralizing titer of 1:1024 or greater, either i.p. or orally does not ... | 1979 | 448139 |
| ontogeny of the ferret humoral immune response. | infant ferrets are born with nearly undetectable immunoglobulin levels, but by 9 days of age the infant ferret serum contains 77, 29, and 13% of adult mean serum levels of igg, iga, and igm. transmucosal uptake of igg by the infant ferret occurred for the first 30 days of life. the specific anti-respiratory syncytial virus neutralizing titer of whole milk was 5.5 times higher than maternal serum despite a lower concentration of immunoglobulins in the milk. | 1979 | 448158 |
| the search for the ideal influenza vaccine. | the history of the development of influenza virus vaccine is traced from its origin with experimental studies of influenza virus in ferrets and mice and the first trials in man. knowledge of the basis of immunity to the viruses in experimental animals and in man has grown steadily over the years and has been essential to successful immunization. virus variation affecting the surface antigens of the virus is seen as the principal obstacle to the application of vaccines in man. so significant are ... | 1979 | 461277 |
| probit analysis of the atrioventricular (av) junctional tissues of the ferret heart. | probit frequency analysis, a graphic method for determining whether a population is normally distributed, skewed, or multinodal, was used to determine whether p cells are present in different regions of the av junction in the ferret heart. this analysis indicated that at least 95% of the cells of the transitional zone, superficial av node, deep av node, and distal av bundle of the ferret heart are morphologically homogeneous. in the proximal av bundle a large cell population is found in addition ... | 1979 | 476796 |
| vagal afferent discharge from tension receptors in the ferret stomach [proceedings]. | 1979 | 480221 | |
| the ferret, mustela putorius furo, as a new species in toxicology. | comprehensive studies on the haematology, urine chemistry, serum chemistry and gross pathology have been carried out and reported. seasonal weight changes were confirmed and were initiated, together with sexual activity, when ferrets were brought in to a constant temperature (18-19 degrees c) and 14-hour daylight cycle during the winter months. levels of haemoglobin, erythrocytes and haematocrit were higher than in most common laboratory species. similarly, serum electrolytes and glucose levels ... | 1979 | 480899 |
| the role of prolactin in implantation and luteal maintenance in the ferret. | 1979 | 486673 | |
| effects of atropine on secretion and motility in isolated gastric mucosa and attached muscularis externa from ferret and cat. | 1. a combined in vitro preparation of gastric mucosa and adjacent muscle from young ferrets and kittens has been used to study the effects of atropine on acid secretion and motility produced by acetylcholine (ach) and pentagastrin.2. the minimal dose of atropine required to abolish a maximum secretory response to ach also prevented the associated motility response. this dose of atropine also blocked the motility response to pentagastrin, but was without influence on the secretory effect of this ... | 1979 | 490363 |
| ouabain increases the slow inward calcium current in ventricular muscle of the ferret [proceedings]. | 1979 | 490409 | |
| behavior of vaccine revertants of temperature-sensitive mutants of influenza virus in ferret tracheal organ culture. | a live attenuated influenza vaccine candidate was not genetically stable when administered to some children who lacked antibody to surface proteins of the virus. to obtain additional biological information about these revertants, the vaccine strain, the wild-type parental strain, and isolates recovered from inoculated children during a vaccine trial were evaluated in ferret tracheal organ culture for effects on the ciliated epithelium and replication at both permissive and restrictive temperatur ... | 1979 | 500202 |
| comparisons of virulence of influenza virus recombinants in ferrets in relation to their behaviour in man and their genetic constitution. | two parent viruses, a/finland/4/74(h3n2) and a/okuda/57(h2n2), virulent and attenuated respectively for man, showed similar differences of virulence in ferrets as judged by estimations of 50% minimal infectious doses (mid50), the level and persistence of nasal infection, the height and duration of pyrexia and the level of lung infection. in ferrets, two recombinant clones, wrl 94(h3n2) and wrl 105(h3n2), were almost as virulent as a/finland and indistinguishable from one another, a result which ... | 1979 | 501338 |
| [seasonal changes of testicular function in two mustelids : ferret (mustela furo l.) and mink (mustela vison s.) (author's transl)]. | 1979 | 501662 | |
| mucosubstance histochemistry of brunner's glands, pyloric glands and duodenal goblet cells in the ferret. | the mucosubstance of brunner's glands, pyloric glands and duodenal goblet cells were studied using the various histochemical methods. the secretions of both brunner's and pyloric glands were similar in their histochemical reactions. they contained neutral mucosubstances as in these glands in man. the duodenal goblet cells showed variations in their histochemical characters. (i) the secretions of most of the deep cells and the majority of superficial cells contained sialidase-labile and sialidase ... | 1979 | 521321 |
| the localization of influenza virus in the respiratory tract of ferrets: susceptible nasal mucosa cells produce and release more virus than susceptible lung cells. | infectious virus production by ferret nasal mucosa and lung organ cultures has been monitored in both tissue pieces and medium over 24 h following inoculation with an asian (h2n2) strain of influenza virus. freshly prepared cultures of nasal mucosa produced approx. 10-fold more virus per cell than fresh lung cultures. also the nasal mucosa cells liberated into the medium a greater proportion (mean 31%) of the total virus produced than did fresh lung (mean 6%). maintenance of lung explants for 24 ... | 1979 | 521800 |
| a correlative light microscopy, transmission and scanning electron microscopy study of the ferret lung. | 1979 | 524059 | |
| anaesthesia of the ranch mink (mustela vison) and ferret (mustela putorius furo). | 1979 | 538879 | |
| [tkhorzofretka (a hybrid of mustela furo l. and m. putorius l.), a new laboratory model animal for plague in carnivores]. | 1979 | 543076 | |
| some observations of anatomical abnormalities and disease states in a population of 350 ferrets (mustela furo l.). | 1979 | 549381 | |
| some aspects of the physiology and anatomy of the cardiovascular system of the ferret, mustela putorius furo. | the resting heart rate was monitored in 50 urethane-anaesthetized (387 +/- 54 beats/min) and 4 conscious (341 +/- 39 beats/min) ferrets. the arterial blood pressure in the anaesthetized animals was 140/110 +/- 35/31 mmhg. the circulatory responses to vagal stimulation, carotid artery occlusion and a variety of humoral agents were examined. the vagal innervation of the heart and of the distribution of the great vessels are described. | 1979 | 553192 |
| easily hydrolyzable, water-soluble derivatives of (+/-)-alpha-5-[1-(indol-3-yl)ethyl]-2-methylamino-delta2-thiazoline-4-one, a novel antiviral compound. | the preparation of a series of indole n-acyl and n-carbamic esters of (+/-)-alpha-5-[1-(indol-3-yl)ethyl]-2-methylamino-delta2-thiazolin-4-one (1) is reported. these derivatives were synthesized as potential water-soluble precursors of the antiviral thiazolinone 1, for evaluation by intranasal administration against influenza and other respiratory infections caused by viruses. salts of the basic carbamic esters (16--19) possess the required water solubility, undergo rapid hydrolysis and decarbox ... | 1979 | 218010 |
| [pathology of the polymorphonuclears in dermatology. methods of investigation. clinical pictures (author's transl)]. | a remarkable increase in the number of recognized clinical abnormalities of neutrophil function has occurred within the 8 years past. of major importance in the delineation of these disorders is the establishment of appropriate methodology of their characterization. this review discusses phagocytosis and its disorders by dividing it into stages that encompass the way in which phagocytes ferret out injection, how they recognize pathogens and the intracellular events leading to engulfment and kill ... | 1979 | 224753 |
| the local origin of the febrile response induced in ferrets during respiratory infection with a virulent influenza virus. | 1979 | 224895 | |
| regional b-cell responses to inactivated influenza virus vaccine in ferrets. | 1979 | 314480 | |
| bilateral cataracts in a ferret. | 1979 | 260553 | |
| adverse effects of lidocaine and methylparaben on tracheal ciliary activity. | the effect of standard concentrations of lidocaine hcl and methylparaben (preservative) on the ciliary activity of ferret tracheal rings in organ culture was assessed. pure lidocaine concentrations as low as 0.5% caused complete ciliostasis which was reversible after removal of the drug. one percent and two percent effects were not completely reversible. pure methylparaben concentrations as low as 0.06 mg/ml paralyzed cilia; and, at concentrations of 0.5 mg/ml or higher, adverse effects were not ... | 1979 | 574178 |
| impairment of tracheal ring ciliary activity by halothane. | the effects of varying concentrations of halothane on tracheal ciliary activity were studied using a ferret tracheal organ culture technique. using 1% and 2% halothane produced no impairment of ciliary activity, while 3% halothane caused some ciliostasis; 4% and 5% halothane produced rapid cessation of ciliary activity. recovery was prompt and complete after exposure to 4% halothane for as long as 3 days, but after 4 days of exposure recovery was incomplete and after a week of exposure death of ... | 1979 | 574736 |
| the development of the atrioventricular node and bundle in the ferret heart. | 1979 | 760490 | |
| salicylate intoxication and influenza in ferrets. | a model of salicylate intoxication was developed in ferrets to permit the evaluation of the interaction with viruses isolated from patients with reye's syndrome. salicylate intoxication produced a mild elevation of the serum glutamic oxaloacetic transaminase and fatty changes in the liver, but these changes differed from those seen in reye's syndrome on light and electron microscopy. salicylates were associated with decreased activity of hepatic phosphorylase and a slight depression of activity ... | 1979 | 432001 |
| urolithiasis in ferrets (mustela putorius). | urinary calculi was observed frequently in ferrets which were from a group used for influenza research. they were submitted for necropsy with various clinical signs. the calculi were composed of magnesium ammonium phosphate hexahydrate and were found in the pelvis of the kidney, urinary bladder and urethra. crystals of undetermined nature occasionally were observed in the kidneys. | 1979 | 459421 |
| the effects of different photoperiods on circadian 5-ht rhythms in regional brain areas and their modulation by pinealectomy, melatonin and oestradiol. | differential circadian rhythms in 5-ht levels were found in the hypothalamus and pineal (but not in the cortex, hippocampus or midbrain) in ferrets kept in either long (14 h light/10 h dark) or short (8 h light/16 h dark) photoperiods. 5-ht decreased during the first 6 h of illumination in all areas examined from animals kept in short photoperiods. in long photoperiods, 5-ht in the hypothalamus (particularly the anterior region) increased during the first 6 h after onset of light and levels in t ... | 1979 | 497810 |
| diphenylhydantoin induced gingival hyperplasia in ferrets: a precautionary note. | diphenylhydantoin appears to modify the tissue response in ferrets to a gingival irritant. in the present study, ferrets were tested for the tissue response to a local irritant in their maxillary right quadrant, while their maxillary left quadrant was the control. a low incidence of hyperplasia was induced only in irritated gingival tissue of animals receiving dph. the problems encountered in comparing the hyperplasia produced in ferrets and humans were also discussed. | 1979 | 288761 |
| control of oestrus in ferrets. | 1979 | 555118 | |
| control of oestrus in ferrets. | 1979 | 573015 | |
| cytoplasmic binding of oestradiol-17beta in several brain regions, pituitary and uterus of ferrets ovariectomized while in or out of oestrus. | the reproductive status at the time of ovariectomy had no effect on oestradiol binding. in both groups of ferrets the oestradiol binding capacity of the uterus was approximately 10 times greater than that of the other tissues studied; of these other tissues the highest oestradiol binding capacity was present in the pituitary, followed by hypothalamus, midbrain, amygdala and cerebral cortex. the binding affinity of hypothalamic receptors for oestradiol was the same in ferrets which had been previ ... | 1979 | 571470 |