Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| an electrophoretic investigation of mammalian spermatid-specific nuclear proteins. | using standardized methods for protein extraction and analysis, the testes of rams, bulls, goats, boars, stallions, rats, cats, hedgehogs, european mink and ferrets were examined for basic spermatid nucleoproteins by electrophoresis. the results suggest that differences exist in the total number of these proteins as well as in the number and amount of the cross-linked cystein-containing proteins. these differences appear to be more family-specific than species-specific. | 1982 | 7077593 |
| haematological and serum chemistry profiles of ferrets (mustela putorius furo). | female, male and castrated male ferrets were studied. weight gain plateaued at 28 weeks of age with males about 500 g heavier than females. no statistically significant differences in haematology were observed with age, but alkaline phosphatase and alanine aminotransferase levels fell while glucose increased. haemolysis led to various changes including marked increases in total protein, albumin, inorganic phosphate and sorbitol dehydrogenase. | 1982 | 7078059 |
| activity of adenylate deaminase and glutamate dehydrogenase in the liver: species and dietary variation. | 1. activity of glutamate dehydrogenase and adenylate deaminase were measured in the livers of carnivores (animals characterised by intake of a high dietary protein). 2. animals studied (ferret, cat, dog, hedgehog, rat, hamster, mouse, cow, pig and rabbit) were kept on their natural diet. 3. glutamate dehydrogenase activity showed no variation between carnivores and non-carnivores. 4. adenylate deaminase activity was significantly higher in carnivores than in non-carnivores. 5. in carnivores, ade ... | 1982 | 7083816 |
| respiratory mechanics of a small carnivore: the ferret. | the ferret, mustela putorius furo, is a small relatively inexpensive carnivore with minimal housing requirements. measurements were made from anesthetized tracheotomized supine males. values obtained during tidal breathing for six animals (576 +/- 12 g) were as follows: tidal volume, 6.06 +/- 0.30 ml; respiratory frequency, 26.7 +/- 3.9 breaths min-1; dynamic lung compliance, 2.48 +/- 0.21 ml cmh2o-1; pulmonary resistance, 22.56 +/- 1.61 cmh2o . l-1 . s. pressure-volume curves from nine ferrets ... | 1982 | 7085416 |
| dirofilariasis in a ferret. | 1982 | 7085481 | |
| ultrastructure and morphometry of the alveolar type ii cell of the ferret. | 1982 | 7086944 | |
| no evidence for cholinergic mechanisms in the control of spontaneous predatory behavior of the ferret. | 1982 | 7089025 | |
| proliferative colitis in ferrets. | during a 4-month period, 31 of 156 ferrets (mustela putorius) in a biomedical research program developed protracted diarrhea. clinical signs were green mucohemorrhagic fecal material, partially prolapsed rectum, anorexia, body weight loss, and dehydration. nine of the affected animals were necropsied. on gross examination, the descending colon was grossly thick and histologically characterized by marked proliferation of the mucosa, relatively few goblet cells, mixed inflammatory cell infiltrate, ... | 1982 | 7091850 |
| ferret foetal infection with influenza virus at early gestation. | 1982 | 7093143 | |
| non-atropinic anticholinergic action of quinidine on the ferret stomach. | 1 the effect of quinidine on the cholinergic response of the ferret gastric corpus was investigated in vivo and in vitro. 2 in vivo, the atropine sensitive contractions of the gastric corpus evoked by stimulation of the cervical vagus in the anaesthetized ferret were antagonized by quinidine (10-30 mg/kg). 3 in vitro, quinidine (10 micrograms/ml) antagonized the contractile response elicited by transmural stimulation (t.m.) of strips of corpus. at this dose of quinidine, the response to acetylch ... | 1982 | 7096390 |
| antigenic and genetic characterization of a novel hemagglutinin subtype of influenza a viruses from gulls. | influenza a virus isolates from ring-billed, franklin, blackback, and herring gulls in the united states possess a hemagglutinin (ha) distinct from the 12 reference ha subtypes. serological assays (hemagglutination inhibition and double-immunodiffusion) with specific antisera to reference strains and to a representative gull isolate showed that the ha of the gull virus was not antigenically related to that of any known subtype. the gull virus did not replicate in ducks or chickens but did replic ... | 1982 | 7097861 |
| the ferret (mustela putorius furo) as an experimental host for brugia malayi and brugia pahangi. | ferrets inoculated subcutaneously with 150--200 infective larvae of brugia malayi (subperiodic strain) usually developed patent infection during the 3rd month post inoculation. microfilaremia was transient, and most animals became amicrofilaremic after the 6th month of infection. ferrets developed a persistent eosinophilia at the time of patency. at necropsy, 5--8 months post infection, adult worms were recovered principally from lymphatic vessels and recovery ranged from 0.5--13% of the inocula ... | 1982 | 7102908 |
| ultrastructure of the pineal gland of the mink (mustela vison). | the pineal gland of the mink (mustela vison) was examined, using light and electron microscopy. its cellular structure was compared with that of the pineal gland in other mammalian species, including that of a close taxonomic relative, the ferret. the pineal gland of the mink was composed to pinealocytes and neuroglial cells, as well as numerous neuron cell processes and nerve endings, which provide extensive neural input to the pineal gland. a high degree of vascularity, extent of neural innerv ... | 1982 | 7103235 |
| anti-influenza a virus activity of amantadine hydrochloride and rimantadine hydrochloride in ferret tracheal ciliated epithelium. | the activities and toxicities of amantadine hydrochloride and rimantadine hydrochloride against influenza a/alaska/6/77 (h3n2) and a/bangkok/1/79 (h3n2) viruses were compared in organ cultures and ferret tracheal ciliated epithelium. pretreatment of cultures with concentrations (0.5 and 1 micrograms/ml) comparable to those found in human serum after oral administration of amantadine revealed that rimantadine produced significantly longer protection than amantadine against virus-induced cytopathi ... | 1982 | 7103458 |
| a comparative study of lysozyme and its secretion by tracheal epithelium. | tracheal explants from baboon, ferret, dog, mouse, hamster, rat guinea pig, chicken, sheep, rabbit and cat were maintained in vivo for 24 to 72 hr. bathing media were analyzed for lysozyme content. secretory rates were compared to the rate obtained for human trachea in our earlier work. these rates ranged from 807 micrograms lysozyme/g tissue/24 hr for human trachea to 11 micrograms lysozyme/g tissue/24 hr for chicken trachea. secretory rates for baboon, ferret dog, mouse, hamster, rat, and guin ... | 1982 | 7106064 |
| applications of ultrasound to veterinary diagnostics in a veterinary teaching hospital. | animal patients at colorado state university's veterinary teaching hospital as well as beagles at the collaborative radiological health laboratory (crhl) have been routinely evaluated using a variety of ultrasonic procedures that are commonplace in human medicine. the results from these clinical investigations have provided diagnostic information which in many cases has not been available using other clinical testing methods. dogs, cats, horses, and cattle have been the primary animals evaluated ... | 1982 | 7107192 |
| the role of vagal and intramural inhibitory reflexes in the regulation of intragastric pressure in the ferret. | 1. the step inflation technique combined with nerve section and pharmacological receptor blockade was used to determine the gastric distribution of the vagal inhibitory fibres and their role in the regulation of intragastric pressure in the anaesthetized ferret.2. under the conditions described the predominant effect of the vagus was inhibitory. the dorsal abdominal vagus mediated more inhibition than the ventral vagal trunk. there was partial overlap in the inhibitory effects of the two trunks ... | 1982 | 7108805 |
| a mobile rack of cages for ferrets (mustela putorius furo). | 1982 | 7109533 | |
| metabolism and excretion of a chromone carboxylic acid (fpl 52757) in various animal species. | 1. the disposition of the chromone carboxylic acid (fpl 52757) in several species has been investigated. the compound is extensively metabolized by hydroxylation in rat, mouse, ferret, squirrel monkey, cynomolgus monkey, rabbit, hamster, stumped-tailed macaque and baboon (e.g. 50-100% in rat, cynomolgus monkey and squirrel monkey). 2. the plasma clearance of the chromone in rat, rabbit and squirrel monkey was 138, 44 and 59 ml/kg per h respectively. plasma clearance by the dog was slower (13 ml/ ... | 1982 | 7113251 |
| mechanism of additive effects of digoxin and quinidine on contractility in isolated cardiac muscle. | to evaluate the mechanism of the effect of the interaction of digoxin and quinidine on myocardial contractility, ferret right ventricular papillary muscles were isolated and the effects of digoxin, 4 x 10(-7) m, quinidine, 1 x 10(5) m and atropine, 1.5 x 10(-6) m, on peak developed force, peak rate of development of force (df/dt) and time to peak tension were determined. the addition of quinidine to muscles treated with digoxin increased developed force 18 percent (p = 0.006) and df/dt 35 percen ... | 1982 | 7113931 |
| isolation of cryptococcus neoformans from a ferret. | 1982 | 7115232 | |
| barbiturates depress vagal motor pathway to ferret trachea at ganglia. | to determine which site in the vagal motor pathway to airway smooth muscle is most sensitive to depression by barbiturates, we recorded isometric muscle tension in vitro and stimulated the vagal motor pathway at four different sites before and after exposure to barbiturates. in isolated tracheal rings from ferrets, we stimulated muscarinic receptors in the neuromuscular junction by exogenous acetylcholine, postganglionic nerve fibers by electrical fluid stimulation, and the postsynaptic membrane ... | 1982 | 7118638 |
| voltage-clamp studies of transient inward current and mechanical oscillations induced by ouabain in ferret papillary muscle. | 1. we studied the effects of a toxic concentration of ouabain on transmembrane electrical activity and on mechanical behaviour of right ventricular papillary muscles from ferrets in a single sucrose-gap using current clamp and voltage clamp.2. ouabain (1.4-1.8 mum) induced oscillatory after-potentials and after-concentrations in current-clamp experiments. voltage clamp showed that the oscillatory after-potential was caused by a transient inward current, similar to that in purkinje fibres.3. the ... | 1982 | 7120138 |
| afferent activity evoked by natural stimulation of the biliary system in the ferret. | a technique for the natural stimulation of the biliary system which permits the distinction between noxious and innocuous intensities of stimulation has been developed in the ferret. male ferrets anaesthetized with urethane have been used. controlled distensions of the biliary system were produced and the nociceptive nature of the stimulus was ascertained by reflex increases in blood pressure. levels of biliary pressure that did not evoke changes in blood pressure were considered innocuous. usin ... | 1982 | 7122106 |
| fine structure of the retinal epithelium, bruch's membrane (complexus basalis) and choriocapillaris in the domestic ferret. | the fine structure of the retinal epithelium, choriocapillaris, and bruch's membrane has been studied by electron microscopy in the domestic ferret. the ferret possesses a tapetum cellulosum in the superior fundus, and the morphology of the retinal epithelium and its associated structures varies depending upon its relation to the tapetum. over the tapetum the retinal epithelium is a single layer of low cuboidal cells with basal infoldings and two types of apical process. internally the cells are ... | 1982 | 7124325 |
| polymedicine: known and unknown drug interactions. | despite more than 15 years of extensive scrutiny, adverse drug interactions, especially in the elderly, remain a problem for the clinician. a two-pronged approach is suggested to contend with drug interactions: detection or avoidance of known drug interactions; and predictions and characterization of hitherto unknown interactions. the former approach is aided by critical reference sources on the subject and the use of drug interaction screening aids such as drug interactions alert lists or rotat ... | 1982 | 7130593 |
| [experimental transmission of rabies to the ferret by an ixodoidea: pholeoixodes rugicollis (schultze and schlottke, 1929)]. | 1982 | 7136476 | |
| is estrogen required for implantation in the ferret? | a series of experiments was designed to further test the hypothesis that ferret corpora lutea synthesize and secrete estrogen between days 6 and 8 of pregnancy, and that this estrogen is required to initiate implantation of blastocysts on day 12. corpora lutea, removed on day 8 of pregnancy contained significant quantities of testosterone. incubation of aliquots of the same luteal tissue for 4 h significantly elevated estrogen levels above those of nonincubated controls. peripheral plasma estrog ... | 1982 | 7139007 |
| evaluation of a cold-recombinant influenza virus vaccine in ferrets. | cold-recombinant strains of influenza virus were derived at 25 c using an attenuated cold-adapted (ca) and temperature-sensitive (ts) a/ann arbor/6/60 (h2n2) strain and wild-type (wt) strains of epidemic relevance. the cold recombinants were characterized in ferrets in terms of clinical manifestations, viral titers, and histopathologic lesions in turbinates and lungs. the data in ferrets showed that cold recombinants with six genes derived from the ca "master" strain and the two surface antigens ... | 1982 | 7142749 |
| spontaneous megakaryocytic myelosis in a four-year-old domestic ferret (mustela furo). | 1982 | 7147617 | |
| lethal occlusion of the gastrointestinal tract in two ferrets (mustela putorius furo l.) due to aberrant voracity. | 1982 | 7148178 | |
| late onset of hearing in the ferret. | onset of hearing in the ferret was judged by simple behavioral, physiological and anatomical indices. the ear canals do not open until the end of the first postnatal month. this coincides with the appearance of a startle response to loud hand claps and the recording of acoustically activated neurons in the midbrain. the late onset of hearing in the ferret (around 32 days postnatal) contrasts with the cat (6 days) and the mouse (12 days). | 1982 | 7150970 |
| fluid fluxes in the ferret trachea. | 1982 | 7151961 | |
| muscarinic receptors in lung and trachea: autoradiographic localization using [3h]quinuclidinyl benzilate. | [3h]quinuclidinyl benzilate binding to slide-mounted frozen sections of ferret lung was of high affinity (kd 63 +/- 14 pm, mean +/- s.e., n = 4), and characteristic of interaction with muscarinic cholinergic receptors. light microscopic autoradiography showed muscarinic receptors to be localized predominantly to smooth muscle of trachea and intrapulmonary cartilaginous airways, and to submucosal glands. there was much less labelling of bronchiolar smooth muscle, airway epithelium and vascular sm ... | 1982 | 7160426 |
| the inadequacy of rectal temperature measurements for assessing the effects of antiviral drugs on influenza virus infection of ferrets. | from 6 experiments in which 99 ferrets were infected with influenza virus a/finland/74 and treated with various agents which suppress virus shedding and other parameters of infection, we assessed whether rectal temperature correlated with nasal virus shedding. a number of temperature and virus-shedding related parameters were determined for each experiment but statistical analysis showed little correlation between them, although an elevated temperature occurred at some time after infection. the ... | 1982 | 7161369 |
| excretion and placental and mammary transfer of hexachlorobenzene in the european ferret (mustela putorius furo). | female european ferrets (mustela putorius furo) absorbed 98.5% of a single dietary exposure of hexachlorobenzene (hcb). the hcb was found to readily cross the placenta and to be excreted in the milk of pregnant/lactating ferrets. after consuming hcb-treated feed, ferrets raising offspring excreted 50% of the initial dose by 32 d, while unbred ferrets achieved this same degree of hcb elimination in 41 d. the percentages of hcb excreted via the urine and feces were approximately 5 and 45%, respect ... | 1982 | 7161840 |
| isolation of mycoplasmas from experimental ferrets (mustela putorius). | a total of 21 apparently healthy experimental ferrets, 8 males and 13 females, comprizing 1, 2 and 3 year-old animals were examined for mycoplasmatales. mycoplasmas were isolated from 17 samples of 21 oral cavities (81.0%), and from 2 of 21 nasal cavities (9.5%), but not from the prepuce or vagina of the animals. neither ureaplasma nor acholeplasma was demonstrated in any of the locations of the ferrets examined. these mycoplasma strains proved to metabolize glucose but not arginine and urea. th ... | 1982 | 7169088 |
| the developing ferret palate--a scanning electron microscope study: i. primary palate and secondary palatal shelves. | palatogenesis was studied in the ferret (mustela putorius) from day 27 to day 29 of gestation. at day 27 the primary palate is present as a flattened shield area, and the two secondary palatal shelves are directed at 45 degrees to the horizontal plane, passing downward on the lateral sides of the tongue, which occupies the space between them. by day 28 the primary palate is bulging convexly in the oral cavity, and the secondary palatal shelves have elevated and are in contact in the midline. fin ... | 1982 | 7174774 |
| effect of stimulation of the vagus nerve in bursts on gastric acid secretion and motility in the anaesthetized ferret. | 1. the effect of electrical stimulation of the vagus nerve with different patterns of impulses (the total number of stimuli remaining constant) on gastric acid secretion and gastric motility were investigated in the anaesthetized ferret. three stimulus patterns were used: continuous, bursts at ten times the continuous frequency but for a tenth of the time, and a natural burst pattern obtained from a recording of vagal efferent fibre discharge. 2. the natural burst pattern gave rise to gastric co ... | 1982 | 7182473 |
| electrophysiological effects of butoprozine on isolated heart preparations. comparison with amiodarone and verapamil. | the electrophysiological effects of butoprozine, a relatively new antiarrhythmic agent, were investigated in sheep cardiac purkinje fibres using a microelectrode technique and in frog atrial and ferret ventricular fibres using a double sucrose gap technique. comparison was made with amiodarone and verapamil. butoprozine increased the action potential duration like amiodarone, depressed the plateau phase like verapamil and decreased the amplitude and the maximum rate of depolarization. pacemaker ... | 1982 | 6978694 |
| cisplatin-induced emesis in the ferret: a new animal model. | the ferret, a carnivore weighing about 1 kg, was evaluated for its potential use in testing drugs for emetic and antiemetic activity. an acute emetic response to apomorphine indicated that the ferret can respond to emetic stimuli and suggested that the ferret has an emetic chemoreceptor trigger zone. cisplatin produced a dose-related emetic response. antagonism with metoclopramide provided complete protection from cisplatin-induced emesis. the results of these initial studies indicate that the f ... | 1982 | 7198011 |
| effect of passive immunization against lh-rh on gonadotropin secretion in the ferret. | administration of ovine antiserum containing antibodies against synthetic lh-rh to spayed female ferrets caused an immediate fall in plasma lh concentration and by 2 h after injection circulating levels had declined by 70--80%. a further decline of 50% was observed on day 2, but by day 4 a return to normal levels had begun and control values were regained on day 6. in contrast, the fall in plasma fsh concentration was delayed, with a significant reduction being first observed on day 2 and minima ... | 1982 | 6798210 |
| excessive nail growth in the european ferret induced by aroclor 1242. | 1982 | 6808932 | |
| catecholamines in the carotid body of several mammalian species: effects of surgical and chemical sympathectomy. | the catecholamine content of the carotid body of several mammalian species has been assayed using high performance liquid chromatography coupled to electrochemical detection and radioenzymatic assays. although there were strain differences in the content of catecholamines in the carotid body of the rat, noradrenaline was equal to or exceeded the dopamine level in this species. no apparent differences were found in carotid bodies of animals killed by cervical dislocation or those dissected from a ... | 1982 | 6817847 |
| free magnesium in sheep, ferret and frog striated muscle at rest measured with ion-selective micro-electrodes. | 1. neutral carrier-based liquid membrane micro-electrodes were constructed which are suitable for continuous measurements of [mg(2+)](i) in cardiac and skeletal muscle preparations.2. the electrodes show a nernstian behaviour in pure mgcl(2) solutions. in the presence of a constant ionic background chosen to simulate the cytoplasmic composition, the calibration function flattens progressively with lower [mg(2+)], due to the interference of k(+) and na(+). the response to changes in [mg(2+)] is l ... | 1982 | 6820662 |
| efficacy of ivermectin against third-stage dirofilaria immitis larvae in ferrets and dogs. | ivermectin prevented maturation of dirofilaria immitis when given per os to ferrets at a dosage of 0 x 1 mg ivermectin per kg bodyweight two days after inoculation with third stage heartworm larvae. similar results were found in dogs treated one day after infection at a dosage of 0 x 05 mg ivermectin per kg. no heartworm were found in the hearts and lungs of five treated dogs compared to an average of 11 worms per dog in five control animals. | 1982 | 6897584 |
| ultrastructural quantitation of connective tissue changes in phenytoin-induced gingival overgrowth in the ferret. | the gingival overgrowth obtained after maintaining ferrets on pht appeared to be due entirely to the effect of the drug, for inflammation induced by banding had no influence on the action of pht in eliciting the overgrowth. the significant change observed was an increase in relative volume of interstitial material (ground substance) in response to pht. although there was no appreciable alteration in numbers of cells present in the lesion, pht had a significant effect on the ultrastructure of fib ... | 1982 | 6953128 |
| the ferret for non-rodent toxicity studies - a pathologist's view. | ferrets have been used in our laboratories over the past 4 years in 12 small drug toxicity studies (14-28 days, 6-8 ferrets, usually male) and recently for a larger study (90 days, 54 ferrets). this has provided a basis for assessing the suitability of the ferret as an alternative species for non-rodent drug toxicity studies. it is amenable to daily dosing by gavage, and it shows gastric damage of a similar type and degree to the dog in response to oral non-steroidal anti-inflammatory drugs. cer ... | 1982 | 6954910 |
| secretion of monovalent ions and water in ferret salivary glands: a micropuncture study. | the acinar mechanisms of secretion of the monovalent ions, na+, k+, cl-, and hco3-, and water in the parotid and submandibular glands of the ferret, mustela putorius furo, were investigated using micropuncture and microanalytical techniques during salivation induced by pilocarpine. the osmolarity and monovalent ionic composition of the primary secretory fluid obtained from the intercalated ducts of these glands were determined. | 1981 | 6937508 |
| intervertebral disc syndrome in a domestic ferret. | 1981 | 6911911 | |
| using jet injection to vaccinate mink and ferrets against canine distemper, mink virus enteritis, and botulism, type c. | 1981 | 6911916 | |
| transductal fluxes of water and monovalent ions in ferret salivary glands. | the net transductal fluxes of water and monovalent ions were measured in the parotid and submandibular salivary glands of the ferret, mustela putorius furo, during stimulation of secretion with pilocarpine. the duct systems of these glands were found to be impermeable to water using the split-oil droplet method for stationary microperfusion of lobular and main ducts. the net transductal fluxes of na+, k+, cl-, and hco3- were characterized by analysis of ductal fluid samples obtained simultaneous ... | 1981 | 6934197 |
| handling of calcium by the ferret submandibular gland. | the handling of ca by the submandibular gland of the ferret during stimulation of salivation with pilocarpine was studied using micropuncture and microanalytical, as well as standard, physiological techniques. concentrations of ionized ca were measured in the fluid from the intercalated, lobular, and main ducts of the gland. the net transductal fluxes of this divalent ion were calculated. | 1981 | 6934198 |
| mucosubstances in the colonic goblet cells of the ferret. | mucosubstances in the colonic goblet cells of the ferret (putorius [mustela] furo) were studied histochemically. they contained predominantly sulphated mucosubstances in the proximal colon and only sulphated mucosubstances in the distal colon. the sulphated mucosubstances were of weakly acidic nature. some deep cells and a few superficial cells in the proximal colon contained sialomucins which were sialidase-sensitive. neutral mucosubstances were not found in the colon. | 1981 | 6455896 |
| immunization of ferrets against dirofilaria immitis by means of chemically abbreviated infections. | ferrets were exposed to two successive inoculations with 30 third-stage larvae of the canine heartworm dirofilaria immitis, the inoculations being approximately 5 months apart. each infection was terminated by ivermectin therapy approximately 2 months after inoculation. the ferrets were challenged with 30 larvae 3 weeks after the termination of the second infection, and were necropsied approximately 6 months after challenge. of the four ferrets that survived this protracted experimentation, two ... | 1981 | 6894638 |
| cell-mediated immunity in ferrets. delayed dermal hypersensitivity, lymphocyte transformation, and macrophage migration inhibitory factor production. | 1981 | 7009242 | |
| canine distemper virus titration in ferret peritoneal macrophages. | the sensitivity of a ferret peritoneal macrophage fluorescent antibody technique for assay of various strains of canine distemper virus was investigated. the macrophage system was compared with established methods of titration in canine kidney cell culture, vero cell culture, and embryonated chicken eggs. it was found to be as sensitive as and in several instances more sensitive than the established methods. | 1981 | 7011675 |
| delayed implantation in mustelids, with special emphasis on the spotted skunk. | three distinct reproductive patterns are exhibited by mustelids. some species (ferret and least weasel) breed during spring and summer and do not exhibit delayed implantation. others (mink and striped skunk) exhibit variable gestation periods with brief periods of delayed implantation occurring only if the females are mated early in the season. most mustelids (western spotted skunk, badgers, marten, wolverine, etc.) always exhibit a prolonged period of delayed implantation lasting several months ... | 1981 | 7014860 |
| immunity to influenza in ferrets. xiv: comparative immunity following infection or immunization with live or inactivated vaccine. | immunization by live influenza virus induced a greater protective effect against subsequent challenge by the homologous virus than by the corresponding killed virus vaccine. furthermore, tracheas excised from 11-day and 28-day influenza-virus-infected ferrets were more resistant to reinfection than tracheas excised from ferrets immunized by killed influenza vaccine, despite equivalent serum antibody titres at these times. histological examination of trachea sections taken from vaccinated and vir ... | 1981 | 7018552 |
| the sympathetic superior cervical ganglia as peripheral neuroendocrine centers. | the superior cervical ganglia (scg) provide sympathetic innervation to the pineal gland, cephalic blood vessels, the choroid plexus, the eye, carotid body and the salivary and thyroid glands. removal of the ganglia brings about several neuroendocrine changes in mammals, including the disruption of water balance in pituitary stalk-sectioned rats, and the alteration of normal photoperiodic control of reproduction in hamsters, ferrets, voles, rams and goats. these effects are commonly attributed to ... | 1981 | 7026734 |
| is there a functional large intestine in the ferret? | the intestine of the ferret (putorius furo) is unusual in that there is no external anatomical division between ileum and colon. up to 8-10 cm from the anus the electrical activity was organized into migrating myoelectric complexes typical of the small intestine. at this point the pattern of electrical activity changed abruptly to that characteristic of the colon, namely short and long spike burst activity. histological examination showed that at this point the muscular layers were interrupted b ... | 1981 | 7238786 |
| equine influenza in the netherlands during the winter of 1978-1979; antigenic drift of the a-equi 2 virus. | influenza virus a-equi 2(heq2neq2) caused an epizootic in the netherlands in the winter of 1978-1979. horses vaccinated with a/equi/praha/56 (heq1neq1) and a/equi/miami/63 (heq2neq2) were also infected and showed clinical signs. the virus involved showed a marked antigenic drift from the prototype and vaccine strain a/equi/miami/63 (heq2neq2). infection of ferrets with the dutch/79 isolates gave rise to high haemagglutination-inhibition antibody titres to a number of a-equi 2-1963, 1968 and 1979 ... | 1981 | 7245173 |
| pulmonary mechanisms of the normal ferret. | pulmonary mechanics were measured in normal anesthetized male fitch ferrets (200-360 g). in eight transorally intubated ferrets, pressure-volume (pv) curves for the lung and chest wall were obtained with an esophageal balloon and body plethysmograph. the lung volumes and capacities expressed as a percentage of the total lung capacity (mean, 49.8 ml) were: vital capacity, 84.7%; inspiratory capacity, 63.7%; inspiratory reserve volume, 58.2%; functional residual capacity, 33.8%; expiratory reserve ... | 1981 | 7263363 |
| surgical extirpation and related anatomy of anal sacs of the ferret. | 1981 | 7263475 | |
| toxicity of amantadine and rimantadine for the ciliated epithelium of ferret tracheal rings. | 1981 | 7264372 | |
| feed consumption and food passage time in mink (mustela vison) and european ferrets (mustela putorius furo). | the amount of feed consumed per day and the rate of food passage was measured in mink and european ferrets. daily feed consumption averaged 40 and 42 g dry matter per kg body weight for male mink and ferrets and 53 and 49 g dry matter per kg body weight for female mink and ferrets, respectively. using ferric oxide as a feed marker, no differences were observed in food passage time between mink and ferrets or between males and females within each species. the mean time of food passage was 187 min ... | 1981 | 7265904 |
| ketamine alone and combined with diazepam or xylazine in laboratory animals: a 10 year experience. | ketamine alone or supplemented by diazepam or xylazine has been used and evaluated as an anaesthetic in a range of animals including snakes, tortoises, lizards, birds, ferrets, dogs, cats, pigs, sheep, goats, non-human primates, rabbits, guinea pigs, rats, mice and hamsters. ketamine alone has severe limitations in most species, but in combination has proved valuable. | 1981 | 7278122 |
| the ultrastructure of the atrioventricular junctional tissues in the newborn ferret heart. | in this study the structure of the atrioventricular (av) node and bundle in the newborn ferret heart was examined by light and electron microscopy. at the light microscopic level the av node could be subdivided into deep and superficial portions. electron microscopy revealed that both superficial and deep av nodal cells were characterized by a paucity of myofibrils, desmosomes, fasciae adherentes and gap junctions. deep v nodal cells, however, had more surface specializations than did superficia ... | 1981 | 7282572 |
| studies of pineal and hypothalamic 5-ht in the ferret. | using a highly sensitive and specific radioenzymatic assay for serotonin (5-ht) in conjunction with a simple reliable technique for removal of small areas of hypothalamus, 5-ht levels have been determined at three time points in several areas of the anterior hypothalamus and the pineal of ovariectomized ferrets housed in long or short day photoperiod. the rhythm seen in all areas of anterior hypothalamus and the pineal was similar in both photoperiods. the data conflict with a previous report fr ... | 1981 | 7284841 |
| histogenesis of the ferret retina. | 1981 | 7286087 | |
| differential distribution of virus and histological damage in the lower respiratory tract of ferrets infected with influenza viruses of differing virulence. | the distribution of four strains of influenza virus [a/pr/8/34 (h0n1) and clone 64d (attenuated for ferrets) and clones 64c and 7a (virulent for ferrets) of the recombinant virus a/pr/8/34--a/england/939/69 (h3n2)] in the lower respiratory tract (trachea, bronchi and the hilar, intermediate and outer alveolar zones of the lung) of ferrets was monitored daily for 4 days after intranasal inoculation. on day 1, some animals had high virus titres in all the tissues but in other animals virus was und ... | 1981 | 7288401 |
| analysis of antigenic drift in the haemagglutinin molecule of influenza b virus with monoclonal antibodies. | antigenic drift in the haemagglutinin (ha) molecule of influenza b viruses was studied with monoclonal antibodies. antigenic drift occurred in each of the 12 different epitopes studied and there was evidence that at least two antigenically distinguishable influenza b virus strains can co-circulate during an epidemic. the frequency of antigenic variation in the ha of influenza a strains. haemagglutination inhibition (hi) tests on antigenic variants selected with 12 different monoclonal antibodies ... | 1981 | 7288409 |
| tracheal submucosal gland serous cells stimulated in vitro with adrenergic and cholinergic agonists. a morphometric study. | a morphometric analysis was made of alterations in serous cell structure induced by adrenergic and cholinergic agonists. ferret tracheal rings were exposed for 30 min in vitro to one of the following agonists: phenylephrine, terbutaline, or methacholine (all at 10(-5) m). controls were incubated similarly in medium containing no drugs or medium containing both the agonist and an excess of the appropriate antagonist (phentolamine, propranolol or atropine, all at 10(-4) m). electron microscopic ob ... | 1981 | 7296643 |
| steady-state vascular responses to graded hypoxia in isolated lungs of five species. | in the isolated pig lung exposed to graded levels of hypoxia, steady-state pulmonary vasomotor tone is maximum at an o2 tension (po2) of 50 torr. below 50-torr decreases in po2 cause steady-state tone to fall below this maximum. to determine whether this stimulus-response relation was peculiar to pigs, we measured the steady-state relation between po2 and vasomotor tone in the isolated lungs of dogs, rabbits, cats, and ferrets, by using identical techniques in each species. marked species differ ... | 1981 | 7298460 |
| quantitative morphological analysis of interatrial muscle cells in the ferret heart. | cells located in the interatrial septum of the ferret heart were examined and mean cell volume, surface area, length, width, as well as cell length/width and surface area/volume ratios were obtained. the muscle cells were from two different regions. one region was the area of the middle internodal tract while the other was from the area where the anterior and middle internodal tracts intermingled. based on the data obtained, at least two different subpopulations of interatrial muscle cells could ... | 1981 | 7305022 |
| replication of avian influenza a viruses in mammals. | the recent appearance of an avian influenza a virus in seals suggests that viruses are transmitted from birds to mammals in nature. to examine this possibility, avian viruses of different antigenic subtypes were evaluated for their ability to replicate in three mammals-pigs, ferrets, and cats. in each of these mammals, avian strains replicated to high titers in the respiratory tract (10(5) to 10(7) 50% egg infective doses per ml of nasal wash), with peak titers at 2 to 4 days post-inoculation, s ... | 1981 | 7309229 |
| the dorsal lateral geniculate nucleus of the normal ferret and its postnatal development. | the anterograde transport of 3h proline and of horseradish peroxidase has been used to study the retinogeniculate pathway in normal adult ferrets and in young ferrets during postnatal development. the lateral geniculate nucleus in adults shows a characteristic "carnivore" pattern, with layers a, a1, c, c1, c2, and c3, and a medial interlaminar nucleus recognizable either cytoarchitectonically or on the basis ofth retinogeniculate innervation. in addition, there is a well-defined, rather large pe ... | 1981 | 7309920 |
| modulation of vagal efferent fibre discharge by mechanoreceptors in the stomach, duodenum and colon of the ferret. | 1. a single-fibre-dissection technique was used to investigate the reflex modulation of vagal efferent fibre discharge by afferent fibres from various parts of the gastrointestinal tract of the urethane-anaesthetized ferret. 2. all but four of the 168 efferent fibres isolated in this study were spontaneously active. the majority of these had discharge frequencies of less than 6 spikes/sec. 3. all the efferent units received an afferent input from mechanoreceptors in the stomach. two main types o ... | 1981 | 7320920 |
| quantitative significance of hypoxic vasoconstriction in the ferret lung. | stimulus-response curves for the pulmonary vascular bed to alveolar hypoxia have been measured in ferrets under conditions of perfusion either at constant pressure or a constant flow in vivo or in isolated lungs. in all circumstances the relationship between alveolar oxygen tension and the fall in blood flow or rise in pulmonary artery pressure was sigmoid although there were important differences between the in vivo and in vitro preparations. the significance of these observations in constant ... | 1981 | 7335988 |
| conference on the ferret as an alternative species in teratology and toxicology. june 25-26, 1981, stanford, california. | 1981 | 7336355 | |
| dopamine and noradrenaline levels in peripheral tissues of several mammalian species. | tissue levels of dopamine (da) and noradrenaline (na) have been compared in atrium, spleen, mesenteric artery, vas deferens and renal cortex of sexually mature rats, guinea-pigs, ferrets, rabbits and cats. the results suggest the presence of dopaminergic autonomic axons in the cat renal cortex, as has been previously reported for the dog. such nerves are probably sparse or absent in the kidneys of the other species examined. | 1981 | 7463085 |
| can you catch rabies from your ferret? probably not. | 1981 | 7206171 | |
| a technique for chronic jugular catheterization in the ferret. | a technique was developed to provide an efficient method for blood sampling and intravenous drug administration in the ferret by using an indwelling jugular catheter. | 1981 | 7208565 |
| external features of the developing ferret embryo. | 1981 | 7225068 | |
| acute effects of hypothalamic lesions upon gonadotrophin secretion in the ferret. | the changes in fsh and lh secretion after placement of lesions in the hypothalamus were traced in ferrets serially bled at 15 min intervals. passage of the lesioning current through platinum electrodes in anoestrous females was associated with an immediate surge in lh and fsh output. damage to the hypothalamus of oestrous females also caused an immediate surge of lh secretion, but then a long-lasting second rise in blood lh content set in. high concentrations of lh were never sustained overnight ... | 1981 | 6788875 |
| repetitive treatment with gonadotrophin releasing factor or a long-acting analogue upon gonadotrophin secretion in the ferret. | the changes in plasma levels of lh and fsh were examined after treatment of intact and ovariectomized females ferrets with a long-acting analogue of gonadotrophin releasing factor (gn-rf) (d-ser(but)6-lh-releasing hormone (1-9)-nonapeptide ethylamide; hoe 766) either as a single intravenous injection or daily for 6 days. the responses were compared with those induced by daily injections of gn-rf or 0.9% nacl (w/v). treatment with gn-rf consistently induced rises in both lh and fsh release with p ... | 1981 | 6790650 |
| changes in fsh and lh secretion in the ferret associated with the induction of ovulation by copper acetate. | 1981 | 6793104 | |
| lymphocyte subpopulations in the ferret. | 1981 | 6797850 | |
| [suitability of ferrets for the ibr-ipv vaccine efficacy evaluation]. | 1981 | 6274304 | |
| field and laboratory studies of equine influenza viruses isolated in 1979. | experimental ponies developed signs of disease four days after the intranasal instillation of a/england 1/79 equine influenza virus and virus was recovered from the nasopharynx from the second to the ninth day. no significant antigenic difference was found between the virus and the prototype a/miami 1/63 virus, using post infection ferret and chicken sera and post vaccination pony sera. no antigenic differences were found between four viruses isolated between january and july 1979, although some ... | 1981 | 6275599 |
| antiviral effects of single-stranded polynucleotide inhibitors of the influenza virion-associated transcriptase against influenza virus infection of hamsters and ferrets. | administration of a single-stranded polynucleotide copolymer containing 9% cytidine residues and 91% 4-thiouridine residues [poly(c,s4u10)], a known potent inhibitor of the virion transcriptase of influenza viruses, suppressed the amount of virus recoverable from the nasal washes of influenza virus-infected hamsters and ferrets. the incidence of sneezing and nasal discharge in infected ferrets was also reduced. in hamsters, poly(c,s4u10) was more effective than amantadine-hcl or virazole. polyin ... | 1981 | 6280608 |
| microradiography, light and electron microscopy of the effects of calcium phosphate solutions on dentine and pulp of the ferret (mustela putorius furo). | 1981 | 6950707 | |
| antigenic and genomic analyses of influenza a(h1n1) viruses from different regions of the world, february 1978 to march 1980. | antigenic analysis of influenza a(h1n1) virus isolates by hemagglutination inhibition reactions with postinfection ferret sera and mouse monoclonal antibodies showed that, although the predominant virus in 1978 to 1979 had an a/brazil/11/78-like hemagglutinin, several new antigenic variants could be detected which differed from those identified in 1977 to 1978. most of the variants showed very minor changes and did not achieve epidemiological significance. genome analysis by ribonucleic acid-rib ... | 1981 | 6163725 |
| the relation of interferon and nonspecific inhibitors to virus levels in nasal washes of ferrets infected with influenza viruses of differing virulence. | two clones (7a, virulent; 64d, attenuated) of a recombinant influenza virus (a/pr/8/34-a/england/939/69 (h3n2)) were inactivated at the same rate by viral inhibitors present in nasal washes taken from both clone 7a- and clone 64d-infected ferrets. both clones induced similar levels of interferon in the nasal washes of infected animals. the onset and rise of interferon production occurred at the same time for both clones, and was associated with a decline in virus titres. in addition, both clones ... | 1981 | 6164382 |
| [new antigenic variants of influenza a(h1n1) virus detected in the ussr in 1979]. | studies of influenza a (h1n1) viruses isolated in the spring of 1979 in the ussr showed all the 73 strains to belong to influenza a (h1n1) virus but to be heterogeneous. apart from the strains identical with the reference a/ussr/90/77 and a/brazil/11/78 as well as intermediate ones, 14 strains were identified and found to be new drift variants. a composite analysis of representative strains of this group (a/ussr/50/79 and a/ussr/61/79) by hi test with diagnostic rat and ferret sera as well as mo ... | 1981 | 6168112 |
| instinctive predatory behavior of mustelids (mustela putorius f. furo, mustela vison f. dom.) modified by benzodiazepine derivatives. | the predatory behavior of the ferret and of the mink consists mainly of instinctive behavioral patterns that are elicited by simple external stimuli. an important stimulus is size of the prey; the time needed to catch and kill defensive prey depends on the size of the prey in relation to that of the predator. benzodiazepine derivatives like chlordiazepoxide or lorazepam affect the prey catching of both species significantly. drugged animals (2 mg/kg orally) need less time to overpower their prey ... | 1981 | 6113610 |
| species differences in the metabolism of 3-phenoxybenzoic acid. | the metabolism of 3-phenoxybenzoic acid (3pba) (10 mg/kg, ip) has been studied in ten mammalian and one avian species in comparison with that of benzoic acid. 3pba exhibits wide species diversity in its metabolism, unlike benzoic acid, of which benzoylglycine (hippuric acid) is the major urinary metabolite in all species studied. with 3pba, glycine conjugation is the major route of metabolism in three species (sheep, cat, and gerbil), whereas in the mouse the taurine conjugate is the principal m ... | 1981 | 6114835 |
| bifluranol, a novel fluorinated bibenzyl anti-androgen, its chemistry and disposition in different animal species. | the synthesis of bifluranol, a new fluorinated bibenzyl anti-androgen, and of 3h-labelled bifluranol is described. the absorption, distribution and excretion of bifluranol has been studied in mouse, rat, ferret and dog; it is readily absorbed following oral administration, but blood concentrations of the drug are low due to hepatic uptake and biliary excretion. enterohepatic re-circulation occurs, but the drug is excreted primarily in the faeces and only small amounts appear in urine. this patte ... | 1981 | 6116777 |
| the metabolism of bifluranol by rat, dog and ferret. | the synthesis of monohydroxy- and dihydroxy-bifluranol, and of glucuronide and sulphate conjugates of bifluranol are described. bifluranol administered orally to rats, ferrets and dogs at a dosage of 50 to 200 microgram kg-1 is mostly excreted in the faeces as unchanged bifluranol and bifluranol monosulphate, disulphate and monoglucuronide. the bifluranol is well absorbed and is mostly excreted in the bile, as six different conjugates, including a glucuronide sulphate found in all 3 species, and ... | 1981 | 6116778 |
| species variations in the renal and hepatic conjugation of 3-phenoxybenzoic acid with glycine. | 1. 3-phenoxy[14c]benzoyl-coa has been chemically synthesized, purified and characterized by field-desorption mass spectrometry. biological activity of the purified thioester was greater than 92%. 2. the two enzymic steps involved in the conjugation of 3-phenoxybenzoic acid (3pba) with glycine have been investigated in hepatic and renal tissues from various mammalian species. 3. a 10- to 300-fold excess of acyl-coa: glycine n-acyltransferase activity as compared with acyl-coa synthetase activity ... | 1981 | 6118977 |