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association between noise exposure and diabetes: a systematic review and meta-analysis.the prevalence of diabetes is on rise worldwide and environmental factors are being increasingly recognized to be involved in this rise. an emerging body of evidence has evaluated the impact of long-term exposure to noise on diabetes mellitus, highlighting the need to synthesize this evidence.201830006240
effect of cabergoline monotherapy in cushing's disease: an individual participant data meta-analysis.the primary treatment of choice for cushing's disease (cd) is the removal of the pituitary adenoma by transsphenoidal surgery (tss). the surgical failure is seen in up to 75% of cases depending on the experience of the surgeon in different studies. medical therapy is one of the options for the treatment of recurrent or persistent cd.201830097903
meta-analysis of gabrb3 gene polymorphisms and susceptibility to autism spectrum disorder.several lines of evidence have suggested that the gaba receptor subunit β3 (gabrb3) gene is a genetic contributor in the autism spectrum disorder (asd). the aberrant expression of gabrb3 is reported in asd patients which may be a consequence of the presence of certain genetic variants in the promoter region of the gene. the associations between single-nucleotide polymorphisms (snps) within this gene and asd have been analyzed in previous studies. however, the results are conflicting. in the pres ...201830074174
epidemiology and aetiologies of cryptococcal meningitis in africa, 1950-2017: protocol for a systematic review.cryptococcal meningitis is a neglected disease and an aids-defining illness, responsible for 15% of all aids-related deaths globally. in 2014, the estimated number of incident cryptococcal meningitis cases was 223 100, with 73% of them occurring in africa. currently available data on the prevalence, incidence, aetiologies and mortality of cryptococcal meningitis across africa are sparse and of limited quality. we propose to conduct the first systematic review to summarise the epidemiological dat ...201830061436
the association between phosphodiesterase type 5 inhibitor use and risk of non-arteritic anterior ischemic optic neuropathy: a systematic review and meta-analysis.phosphodiesterase type 5 inhibitors (pde5-is) are first-line drugs for erectile dysfunction. non-arteritic anterior ischemic optic neuropathy (naion) has been linked with pde5-i use. however, no meta-analysis or conclusive review has explored the association between naion and pde5-i use.201829884471
civilian gunshot wounds to the head: prognostic factors affecting mortality: meta-analysis of 1774 patients.civilian gunshot wounds to the head (cgswh) are devastating, but there is no consensus regarding prognosis and management. therefore, we conducted a meta-analysis to identify prognostic factors associated with mortality. pubmed, embase, scopus, web of science, and cochrane library were queried for retrospective cohort studies of isolated cgswh reporting mortality prognostic factors. meta-analysis of observational studies in epidemiology (moose) guidelines were followed. study quality was assesse ...201829877141
vitamin d and risk of preeclampsia: a systematic review and meta-analysis.human vitamin d levels have been increasingly related to a wide range of clinicaloutcomes. there is a large amount of reports on its associations, especially with obstetric complications,including preeclampsia and gestational diabetes. these results are scarcely consistent and there is stilla lack of quality intervention studies to confirm the role of vitamin d in those outcomes.objective: to review the available scientific evidence on the role of maternal vitamin d in the developmentof preeclam ...201829874709
association of hypertensive disorders of pregnancy with risk of neurodevelopmental disorders in offspring: a systematic review and meta-analysis.although research suggests an association between hypertensive disorders of pregnancy (hdp) and autism spectrum disorder (asd), attention-deficit/hyperactivity disorder (adhd), and other neurodevelopmental disorders in offspring, consensus is lacking. given the increasing prevalence of hypertension in pregnancy, it is important to examine the association of hdp with neurodevelopmental outcome.201829874359
incorporating road crossing data into vehicle collision risk models for moose (alces americanus) in massachusetts, usa.wildlife-vehicle collisions are a human safety issue and may negatively impact wildlife populations. most wildlife-vehicle collision studies predict high-risk road segments using only collision data. however, these data lack biologically relevant information such as wildlife population densities and successful road-crossing locations. we overcome this shortcoming with a new method that combines successful road crossings with vehicle collision data, to identify road segments that have both high b ...201829744581
prevalence and risk factors for musculoskeletal pain in keyboard musicians: a systematic review.to identify the prevalence and risk factors for musculoskeletal pain in keyboard musicians.201829705171
human papillomavirus vaccine and demyelinating diseases-a systematic review and meta-analysis.approved in 2006, human papillomavirus (hpv) vaccines were initially targeted for girls aged 9-14 years. although the safety of these vaccines has been monitored through post-licensure surveillance programmes, cases of neurological events have been reported worldwide. the present study aimed to assess the risk of developing demyelination after hpv immunization by meta-analysing risk estimates from pharmacoepidemiologic studies. a systematic review was conducted in medline, embase, isi web of sci ...201829665426
what have we learned in minimally invasive colorectal surgery from nsqip and nis large databases? a systematic review."big data" refers to large amount of dataset. those large databases are useful in many areas, including healthcare. the american college of surgeons national surgical quality improvement program (acs-nsqip) and the national inpatient sample (nis) are big databases that were developed in the usa in order to record surgical outcomes. the aim of the present systematic review is to evaluate the type and clinical impact of the information retrieved through nisqp and nis big database articles focused ...201829623415
stereotactic ablative radiation therapy versus surgery in early lung cancer: a meta-analysis of propensity score studies.as no completed randomized trials of surgery versus stereotactic ablative radiation therapy (sabr) in patients with early-stage non-small cell lung cancer are available, numerous propensity score studies have attempted to mimic the setting of clinical trials using nonrandomized data. we performed a meta-analysis of propensity score studies comparing sabr and surgery.201829619964
accuracy of quick sequential organ failure assessment (qsofa) score and systemic inflammatory response syndrome (sirs) criteria for predicting mortality in hospitalized patients with suspected infection: a meta-analysis of observational studies.to identify sensitivity, specificity and predictive accuracy of quick sequential organ failure assessment (qsofa) score and systemic inflammatory response syndrome (sirs) criteria to predict in-hospital mortality in hospitalized patients with suspected infection.201829605565
dash cam videos on youtube™ offer insights into factors related to moose-vehicle collisions.to gain a better understanding of the dynamics of moose-vehicle collisions, we analyzed 96 videos of moose-vehicle interactions recorded by vehicle dash-mounted cameras (dash cams) that had been posted to the video-sharing website youtube™. our objective was to determine the effects of road conditions, season and weather, moose behavior, and driver response to actual collisions compared to near misses when the collision was avoided. we identified 11 variables that were consistently observable in ...201829598877
periodontal disease has an impact on patients' quality of life.data sourcesmedline, embase, opengrey, journal of clinical periodontology, journal of periodontology and a hand search of the bibliographies of retrieved publications.study selectiontwo reviewers screened the title and abstract of 1134 studies from the literature and selected 37 suitable publications for inclusion following full text analysis of 109 papers and agreement between both reviewers. the search included observational, epidemiological studies and clinical trials that fufilled the inclus ...201829568030
gastrointestinal metastasis from primary lung cancer. case series and systematic literature review.aim of the present study is to report clinical characteristics and outcomes of patients treated in authors' hospital for gi metastasis from primary lung cancer, and to report and analyse the same data concerning patients retrieved from a systematic literature review. we performed a retrospective analysis of prospectively collected data, and a systematic review using the meta-analysis of observational studies in epidemiology (moose) guidelines. ninety-one patients were included, 5 patients from t ...201829567360
proximal embolic protection versus distal filter protection versus combined protection in carotid artery stenting: a systematic review and meta-analysis.proximal embolic protection devices (p-epd) and distal filters (df) are used to prevent distal cerebral embolizations during carotid artery stenting (cas). we compared their comparative effectiveness in regards to prevention of intraprocedural and periprocedural adverse events, including ischemic lesions (ipsilateral and contralateral), stroke, transient ischemic attacks (tia) and death. we also compared the combination of the two neuroprotection strategies vs. a single strategy in regards to is ...201829502959
disparities in the management of cardiovascular risk factors in patients with psychiatric disorders: a systematic review and meta-analysis.the high cardiovascular (cv) morbidity and mortality reported for patients with psychiatric disorders may possibly be due to a poorer management of cv risk factors (cvrfs). however, these healthcare disparities remain poorly understood. in this paper, studies comparing the management of smoking, diabetes, hypertension and dyslipidaemia, in patients with and without depression, anxiety, schizophrenia, bipolar or personality disorder, were reviewed.201829490716
meta-analysis of risk of developing malignancy in congenital choledochal malformation.choledochal malformations comprise various congenital cystic dilatations of the extrahepatic and/or intrahepatic biliary tree. choledochal malformation is generally considered a premalignant condition, but reliable data on the risk of malignancy and optimal surgical treatment are lacking. the objective of this systematic review was to assess the prevalence of malignancy in patients with choledochal malformation and to differentiate between subtypes. in addition, the risk of malignancy following ...201829480528
cognitive outcomes of children born extremely or very preterm since the 1990s and associated risk factors: a meta-analysis and meta-regression.despite apparent progress in perinatal care, children born extremely or very preterm (ep/vp) remain at high risk for cognitive deficits. insight into factors contributing to cognitive outcome is key to improve outcomes after ep/vp birth.201829459939
hepatitis b vaccination and the putative risk of central demyelinating diseases - a systematic review and meta-analysis.the anti-hepatitis b immunization campaigns launched in the early 1990s were a major public health breakthrough and targeted various populations (at-risk adults, newborns, adolescents). however, debate is still active about a possible link between this vaccine and central demyelination. this study provides a pooled estimate of this risk based on a comprehensive review and meta-analysis of all available epidemiologic studies.201829454521
incidence, prevalence and clinical correlates of antidepressant-emergent mania in bipolar depression: a systematic review and meta-analysis.treatment-emergent mania (tem) represents a common phenomenon inconsistently reported across primary studies, warranting further assessment.201829441650
novel type of chronic wasting disease detected in moose (alces alces), norway.chronic wasting disease (cwd) persists in cervid populations of north america and in 2016 was detected for the first time in europe in a wild reindeer in norway. we report the detection of cwd in 3 moose (alces alces) in norway, identified through a large scale surveillance program. the cases occurred in 13-14-year-old female moose, and we detected an abnormal form of prion protein (prpsc) in the brain but not in lymphoid tissues. immunohistochemistry revealed that the moose shared the same neur ...201830457526
moose ( alces alces) mortality associated with caprine herpesvirus 2 (cphv-2) in a zoological collection.malignant catarrhal fever (mcf) can affect both domestic and wild artiodactyls. in a zoological setting, in which subclinical carriers and susceptible species are often housed in close proximity, the disease can prove fatal. this report describes a case of goat-associated mcf in a captive moose ( alces alces). the diagnosis was confirmed by histopathology, which showed lymphocytic vasculitis in the brain and panuveitis, and by detection of caprine herpesvirus 2 dna in tissues. identical viral dn ...201830212315
emergence of the arterial worm elaeophora schneideri in moose (alces alces) and tabanid fly vectors in northeastern minnesota, usa.moose (alces alces) are a culturally and economically valued species in minnesota. however, the moose population has experienced a sudden, marked decline in their range, including extirpation in the northwest and a 66% decline in the last decade in the northeast portions of the state. although the exact cause of this decline is unclear, parasitic metastrongylid and filarioid nematode infections are known causes of morbidity and mortality in moose across north america.201830201046
a novel technique for isolating dna from tempus™ blood rna tubes after rna isolation.we use tempus blood rna tubes (applied biosystems) during health assessments of american moose (alces alces spp.) as a minimally invasive means to obtain rna. here we describe a novel protocol to additionally isolate high-quality dna from the supernatant remaining after the rna isolation methodology. metrics used to qualify dna quality included measuring the concentration, obtaining a dna integrity number from a genomic dna screentape assay (agilent), and running the isolated dna on an agarose g ...201830081941
microfilariae onchocerca alcis bain et rehbinder, 1986 – a new parasite of moose alces alces (l.) in polandonchocerca alcis bain et rehbinder, 1986 belongs to the subfamily onchocercinae. mature nematodes of o. alcis are located on the surface of hindlimb tendons. the aim of this article was to describe the occurrence of microfilariae of o. alcis in the skin of moose from kampinos forest. this is the first report of o. alcis in moose from poland and the third finding of this rare species in the world.201829983019
effective thiafentanil immobilization and physiological responses of free-ranging moose (alces alces) in northern sweden.to evaluate clinical and physiological responses in moose to thiafentanil administration for immobilization.201829891211
discovery of snps for individual identification by reduced representation sequencing of moose (alces alces).monitoring of wild animal populations is challenging, yet reliable information about population processes is important for both management and conservation efforts. access to molecular markers, such as snps, enables population monitoring through genotyping of various dna sources. we have developed 96 high quality snp markers for individual identification of moose (alces alces), an economically and ecologically important top-herbivore in boreal regions. reduced representation libraries constructe ...201829847564
an in vitro evaluation of browser and grazer fermentation efficiency and microbiota using european moose spring and summer foods.evolutionary morphological and physiological differences between browsers and grazers contribute to species-specific digestion efficiency of food resources. rumen microbial community structure of browsers is supposedly adapted to characteristic nutrient composition of the diet source. if this assumption is correct, domesticated ruminants, or grazers, are poor model animals for assessing the nutritional value of food consumed by browsing game species. in this study, typical spring and summer food ...201829721290
a technique for deployment of rumen bolus transmitters in free-ranging moose ( alces alces).recent uses for rumen boluses, such as mortality implant transmitters (mits), in wildlife have made it necessary to adapt deployment techniques developed for livestock. in 29 and 30 attempts to place mits in minnesota free-ranging moose ( alces alces) in 2013 and 2014, respectively, success was achieved 83% and 63% of the time. in 2014, new methods for mit deployment were evaluated in captive moose in alaska. mandible measurements provided guidance for selection of an appropriate-sized bolus app ...201829517432
a snp resource for studying north american moose.background: moose ( alces alces) colonized the north american continent from asia less than 15,000 years ago, and spread across the boreal forest regions of canada and the northern united states (us).  contemporary populations have low genetic diversity, due either to low number of individuals in the original migration (founder effect), and/or subsequent population bottlenecks in north america.  genetic tests based on informative single nucleotide polymorphism (snp) markers are helpful in forens ...201829479424
transuterine infection by baylisascaris transfuga: neurological migration and fatal debilitation in sibling moose calves (alces alces gigas) from alaska.larval baylisascaris nematodes (l3), resulting from transuterine infection and neural migration, were discovered in the cerebrum of sibling moose calves (alces alces gigas) near 1-3 days in age from alaska. we provide the first definitive identification, linking morphology, biogeography, and molecular phylogenetics, of baylisascaris transfuga in naturally infected ungulates. life history and involvement of paratenic hosts across a broader assemblage of mammals, from rodents to ungulates, in the ...201830094177
brown bear (ursus arctos) attacks resulting in human casualties in scandinavia 1977-2016; management implications and recommendations.human persecution and habitat loss have endangered large carnivore populations worldwide, but some are recovering, exacerbating old conflicts. carnivores can injure and kill people; the most dramatic form of wildlife-human conflict. in scandinavia, the brown bear (ursus arctos) population increased from ~500 bears in 1977 to ~3300 in 2008, with an increase in injuries, fatalities, and public fear of bear attacks. we reviewed media coverage and interviewed victims to explore how bear population t ...201829791471
identification of circular single-stranded dna viruses in faecal samples of canada lynx (lynx canadensis), moose (alces alces) and snowshoe hare (lepus americanus) inhabiting the colorado san juan mountains.the san juan mountains of southern colorado provide subalpine habitat for a suite of mammalian species including canada lynx (lynx canadensis), moose (alces alces) and snowshoe hare (lepus americanus). in the winter field season of 2016 five faecal samples from lynx, and one each from moose and snowshoe hare were collected to identify small single-stranded dna viruses associated with these three prominent species. thirty-two novel viruses were identified and classified as members of two well est ...201829879480
suitability of wild boar (sus scrofa) as a bioindicator for environmental pollution with perfluorooctanoic acid (pfoa) and perfluorooctanesulfonic acid (pfos).wildlife species, such as roe deer, moose, brown hare, wild boar, etc., are known to accumulate persistent environmental contaminants and thus are useful as bioindicators for environmental pollution. wild boars become exposed to perfluorooctanoic acid (pfoa) and perfluorooctanesulfonic acid (pfos) from flora, fauna, water, and soil. the main exposure pathway to pfoa and pfos is assumed to be the oral intake. from studies in domestic pigs (belonging to the same species sus scrofa), it has been es ...201830116839
the european union summary report on surveillance for the presence of transmissible spongiform encephalopathies (tses) in 2017.this report presents the results of surveillance on transmissible spongiform encephalopathies (tses) in bovine animals, sheep, goats, cervids and other animal species, as well as genotyping in sheep, carried out in 2017 in the european union (eu) according to regulation (ec) 999/2001, and in iceland, norway and switzerland. in total, 1,312,714 cattle were tested by the 28 eu member states (mss) which is a decrease of 3% compared with 2016; 18,526 were tested by the three non-mss. for the first t ...201832625769
susceptibility of human prion protein to conversion by chronic wasting disease prions.chronic wasting disease (cwd) is a contagious and fatal neurodegenerative disease and a serious animal health issue for deer and elk in north america. the identification of the first cases of cwd among free-ranging reindeer and moose in europe brings back into focus the unresolved issue of whether cwd can be zoonotic like bovine spongiform encephalopathy. we used a cell-free seeded protein misfolding assay to determine whether cwd prions from elk, white-tailed deer, and reindeer in north america ...201830014840
sika deer (cervus nippon)-specific real-time pcr method to detect fraudulent labelling of meat and meat products.since game meat is more valuable and expensive than meat from domesticated animal species it is a potential target for adulteration. analytical methods must allow the identification and quantification of meat species to be applicable for the detection of fraudulent labelling. we developed a real-time pcr assay for the authentication of sika deer (cervus nippon) and products thereof. the primer/probe system amplifies a 71 bp fragment of the kappa-casein precursor gene. since the target sequence c ...201829739996
scientific opinion on chronic wasting disease (ii).the european commission asked efsa for a scientific opinion on chronic wasting disease in two parts. part one, on surveillance, animal health risk-based measures and public health risks, was published in january 2017. this opinion (part two) addresses the remaining terms of reference, namely, 'are the conclusions and recommendations in the efsa opinion of june 2004 on diagnostic methods for chronic wasting disease still valid? if not, an update should be provided', and 'update the conclusions of ...201832625679
soil humic acids degrade cwd prions and reduce infectivity.chronic wasting disease (cwd), an environmentally transmissible, fatal prion disease is endemic in north america, present in south korea and has recently been confirmed in northern europe. the expanding geographic range of this contagious disease of free-ranging deer, moose, elk and reindeer has resulted in increasing levels of prion infectivity in the environment. soils are involved in cwd horizontal transmission, acting as an environmental reservoir, and soil mineral and organic compounds have ...201830496301
mycoplasma ovipneumoniae in wildlife species beyond subfamily caprinae.elucidating the emergence of mycoplasma ovipneumoniae-associated respiratory disease in ruminants requires identification of the pathogen host range. this bacterium was thought to be host restricted to subfamily caprinae, but we describe its identification in healthy moose, caribou, and mule deer and diseased mule and white-tailed deer, all species in subfamily capreolinae.201830457547
cadmium exposure in first nations communities of the northwest territories, canada: smoking is a greater contributor than consumption of cadmium-accumulating organ meats.traditional food consumption among northern populations is associated with improved nutrition but occasionally can also increase contaminant exposure. high levels of cadmium in the organs of moose from certain regions of the northwest territories, canada, led to the release of consumption notices. these notices recommended that individuals limit their consumption of kidney and liver from moose harvested from the southern mackenzie mountain. a human biomonitoring project was designed to better ch ...201830221302
food in rural northern norway in relation to sami ethnicity: the saminor 2 clinical survey.to estimate current food intake in the population of northern norway and to investigate the impact of self-perceived sami ethnicity and region of residence on food intake.201829808789
is ungulate migration culturally transmitted? evidence of social learning from translocated animals.ungulate migrations are assumed to stem from learning and cultural transmission of information regarding seasonal distribution of forage, but this hypothesis has not been tested empirically. we compared the migratory propensities of bighorn sheep and moose translocated into novel habitats with those of historical populations that had persisted for hundreds of years. whereas individuals from historical populations were largely migratory, translocated individuals initially were not. after multiple ...201830190405
environmental toxic metal contaminants and risk of cardiovascular disease: systematic review and meta-analysis.to conduct a systematic review and meta-analysis of epidemiological studies investigating the association of arsenic, lead, cadmium, mercury, and copper with cardiovascular disease.201830158148
systematic review and meta-analysis of the risk of bowel ischemia after ruptured abdominal aortic aneurysm repair.outcomes after repair of ruptured abdominal aortic aneurysm (raaa) have improved in the last decade. it is unknown whether this has resulted in a reduction of postoperative bowel ischemia (bi). the primary objective was to determine bi prevalence after raaa repair. secondary objectives were to determine its major sequelae and differences between open repair (or) and endovascular aneurysm repair (evar).201830146037
potato consumption and risk of type 2 diabetes: a dose-response meta-analysis of cohort studies.high potato intake has been suggested as a risk factor for the development of type 2 diabetes. we aimed to investigate the association between potato consumption and risk of type 2 diabetes.201830144898
antibiotic de-escalation in patients with pneumonia in the intensive care unit: a systematic review and meta-analysis.antibiotic de-escalation is part of an antibiotic stewardship strategy to achieve adequate therapy for infections while avoiding the prolonged use of broad-spectrum antibiotics. however, there is a paucity of clinical evidence on the clinical impact of this strategy in pneumonia patients in the intensive care unit (icu). this review aimed to evaluate the impact of antibiotic de-escalation therapy for adult patients diagnosed with pneumonia in the icu.201830144239
does bariatric surgery cause vitamin a, b1, c or e deficiency? a systematic review.the restrictive and/or malabsorptive nature of bariatric surgery may increase the risk for micronutrient deficiencies. this systematic review aimed to identify and critique the evidence for vitamin a, b1, c or e deficiencies associated with bariatric surgery.201830120641
prevalence of attention deficit hyperactivity disorder in detention settings: a systematic review and meta-analysis.background: previous studies have reported a high prevalence of attention deficit hyperactivity disorder (adhd) among people living in detention (pld) corresponding to a five- to ten-fold increase compared to the general population. our main study objective was to provide an updated adhd prevalence rate for pld, including pld in psychiatric units. sub-objectives included (i) comparing different ways of assessing adhd, including dsm-5 criteria and (ii) identifying which types of pld are more like ...201830116206
erratum: moose at their bioclimatic edge alter their behavior based on weather, landscape, and predators.[this corrects the article doi: 10.1093/cz/zox047.]201830109871
parameter optimization using covariance matrix adaptation-evolutionary strategy (cma-es), an approach to investigate differences in channel properties between neuron subtypes.computational models in neuroscience can be used to predict causal relationships between biological mechanisms in neurons and networks, such as the effect of blocking an ion channel or synaptic connection on neuron activity. since developing a biophysically realistic, single neuron model is exceedingly difficult, software has been developed for automatically adjusting parameters of computational neuronal models. the ideal optimization software should work with commonly used neural simulation sof ...201830108495
associations between common ion channel single nucleotide polymorphisms and sudden cardiac death in adults: a moose-compliant meta-analysis.we sought to identify common ion channel single nucleotide polymorphisms (snps) associated with the occurrence of sudden cardiac death (scd) to predict the incidence of scd in clinical settings.201830235722
meta-analyses using real-world data to generate clinical and epidemiological evidence: a systematic literature review of existing recommendations.to identify existing guidelines, key recommendations, and existing limitations regarding the evaluation and use of real-world evidence (rwe) in meta-analyses (mas) to generate clinical and epidemiological evidence: a systematic review of existing recommendations.201830217138
the association between transforming growth factor beta1 polymorphism and susceptibility to pulmonary fibrosis: a meta-analysis (moose compliant).although many studies have investigated the association of single nucleotide polymorphisms (snps) in transforming growth factor beta1 (tgf-β1) gene with pulmonary fibrosis (pf), but their association is still controversial. to clarify this, we performed a meta-analysis.studies related to tgf-β1 and pf were retrieved from pubmed, medline, embase, scopus, and wanfang (up to november 30, 2017). we targeted tgf-β1 snps that have been reported by ≥3 studies to be included in the current meta-analysis ...201830212926
classic wolf-moose study to be restarted on isle royale. 201830262476
leaf herbivory by insects during summer reduces overwinter browsing by moose.damage to plants by herbivores potentially affects the quality and quantity of the plant tissue available to other herbivore taxa that utilize the same host plants at a later time. this study addresses the indirect effects of insect herbivores on mammalian browsers, a particularly poorly-understood class of interactions. working in the alaskan boreal forest, we investigated the indirect effects of insect damage to salix interior leaves during the growing season on the consumption of browse by mo ...201830261869
efficacy of breast reconstruction with fat grafting: a systematic review and meta-analysis.breast reconstruction with fat grafting is a new alternative to prosthetic implants and flaps for women with breast cancer. in this study, we investigate the efficacy of fat grafting for breast reconstruction in a meta-analysis.201830245019
cognitive functions in children and adults with moyamoya vasculopathy: a systematic review and meta-analysis.patients with moyamoya vasculopathy (mmv) may experience cognitive impairment, but its reported frequency, severity, and nature vary. in a systematic review and metaanalysis, we aimed to assess the presence, severity, and nature of cognitive impairments in children and adults with mmv.201830309228
playboy bunny and moose head sign: hepatic veins in congestive heart failure. 201830309097
the association between dental anxiety and psychiatric disorders and symptoms: a systematic review.a growing amount of evidence suggests that dental anxiety is associated with other psychiatric disorders and symptoms. a systematic review was conducted to critically evaluate the studies of comorbidity of dental anxiety with other specific phobias and other axis i psychiatric disorders.201830288171
the usefulness of listening social media for pharmacovigilance purposes: a systematic review.social media mining could be a possible strategy to retrieve drug safety information. the mining of social media is a complex process under progressive evolution, falling into three broad categories: listening (safety data reporting), engaging (follow-up), and broadcasting (risk communication). this systematic review is aimed at evaluating the usefulness and quality of proto-signals by social media listening. areas covered: in this systematic search, performed according to moose and prisma state ...201830285501
amyotrophic lateral sclerosis and occupational exposures: a systematic literature review and meta-analyses.objectives: we conducted a systematic literature review to identify studies fulfilling good scientific epidemiological standards for use in meta-analyses of occupational risk factors for amyotrophic lateral sclerosis (als). methods: we identified 79 original publications on associations between work and als. the moose (meta-analysis of observational studies in epidemiology) and grade (grading of recommendations, assessment, development and evaluations) guidelines were used to ensure high scienti ...201830373166
interspecies cross-feeding orchestrates carbon degradation in the rumen ecosystem.because of their agricultural value, there is a great body of research dedicated to understanding the microorganisms responsible for rumen carbon degradation. however, we lack a holistic view of the microbial food web responsible for carbon processing in this ecosystem. here, we sampled rumen-fistulated moose, allowing access to rumen microbial communities actively degrading woody plant biomass in real time. we resolved 1,193 viral contigs and 77 unique, near-complete microbial metagenome-assemb ...201830356154
association of psoriasis with inflammatory bowel disease: a systematic review and meta-analysis.patients with psoriasis may experience comorbidities involving cardiovascular diseases, chronic kidney disease, uveitis, psychiatric disturbances, and metabolic syndrome. however, the association between psoriasis and inflammatory bowel disease (ibd) has been largely unclear.201830422277
xrcc1 polymorphism and overall survival in ovarian cancer patients treated with platinum-based chemotherapy: a systematic review and moose-compliant meta-analysis.although platinum-based chemotherapy is widely used for advanced ovarian cancer (oc), genetic polymorphisms can influence the chemotherapeutic response. this study investigated the association between xrcc1 polymorphisms arg194trp, arg280his, and arg399gln, and overall survival (os) in oc patients who received platinum-based chemotherapy.201830407287
early post-stroke depression and mortality: meta-analysis and meta-regression.background: post-stroke depression (psd) is a common and serious complication after stroke. in this systematic review and meta-analysis, we evaluated the association between early psd and mortality, considering depressive symptoms occurring within the first 3 months after the neurological event. methods: this meta-analysis was conducted following meta-analysis of observational studies in epidemiology (moose) guidelines and based on studies indexed till may 2018 in pubmed and web of science datab ...201830443225
effect of long term aspirin use on the incidence of prostate cancer: a systematic review and meta-analysis.previous studies found divergent effects of aspirin use on prostate cancer incidence, potentially due to studies with short durations of aspirin use and insufficient adjustment for screening.201830447928
multiscale entropy rate analysis of complex mobile agents.accurate prediction of the motion of objects is a central scientific goal. for deterministic or stochastic processes, models exist which characterize motion with a high degree of reliability. for complex systems, or those where objects have a degree of agency, characterizing motion is far more challenging. the information entropy rate of motion through a discrete space can place a limit on the predictability of even the most complex or history-dependent actor, but the variability in measured enc ...201830473814
improving the quality of reporting of systematic reviews of dose-response meta-analyses: a cross-sectional survey.dose-response meta-analysis (drma) is a useful tool to investigate potential dose-response relationship between certain exposure or intervention and the outcome of interest. a large number of drmas have been published in the past several years. however, the standard of reporting for such studies is not known.201830497389
surgical outcomes for medically intractable epilepsy in low- and middle-income countries: a systematic review and meta-analysis.objectivethe aim of this study was to describe the current state of epilepsy surgery and establish estimates of seizure outcomes following surgery for medically intractable epilepsy (mie) in low- and middle-income countries (lmics).methodsthe medline and embase databases were searched without publication date restriction. this search was supplemented by a manual screen of key epilepsy and neurosurgical journals (january 2005 to december 2016). studies that reported outcomes for at least 10 patie ...201830497170
association between obesity and cardiovascular outcomes: a systematic review and meta-analysis of mendelian randomization studies.although dyslipidemia has been consistently shown to be associated with atherogenesis, an association between obesity and cardiovascular disease outcomes remains controversial. mendelian randomization can minimize confounding if variables are randomly and equally distributed in the population of interest.201830646365
association of levels of physical activity with risk of parkinson disease: a systematic review and meta-analysis.the association between physical activity and the risk of parkinson disease (pd) has been increasingly recognized. however, to our knowledge, a comprehensive assessment of the quantitative dose-response association between physical activity and pd risk has not been performed previously.201830646166
association of mortality and acute aortic events with ascending aortic aneurysm: a systematic review and meta-analysis.the natural history of ascending aortic aneurysm (asaa) is currently not well characterized.201830646119
tea consumption is associated with decreased risk of oral cancer: a comprehensive and dose-response meta-analysis based on 14 case-control studies (moose compliant).the associations of tea consumption with risk of oral cancer remain not clear. the present meta-analysis aims to clarify the real relationship between tea intake and the risk of oral cancer and quantifies the potential dose-response relationship between them.a web search was performed within pubmed, embase, and web of science databases to identify potential studies that evaluated the relationship between tea consumption and the risk of oral cancer on mar 21th, 2018 without language restriction. ...201830572470
comparison of the clinical outcomes of revision of failed ukas to tkas with primary tkas: a systematic review and meta-analysis.unicompartmental knee arthroplasty (uka) is one of the effective surgical methods for the treatment of unicompartmental knee arthritis. when uka fails, a revised surgery to total knee arthroplasty (tka) is often necessary. the purpose of this study was to compare the clinical outcomes of revision of failed ukas to tkas with primary tkas. the hypothesis was that the tkas revised from ukas had inferior clinical outcomes compared with primary tkas.this meta-analysis was conducted in accordance with ...201830557995
chronic wasting disease (cwd) in cervids.in april and may of 2016, norway confirmed two cases of chronic wasting disease (cwd) in a wild reindeer and a wild moose, respectively. in the light of this emerging issue, the european commission requested efsa to recommend surveillance activities and, if necessary, additional animal health risk-based measures to prevent the introduction of the disease and the spread into/within the eu, specifically estonia, finland, iceland, latvia, lithuania, norway, poland and sweden, and considering seven ...201732625260
molecular taxonomy and subgeneric classification of tapeworms of the genus moniezia blanchard, 1891 (cestoda, anoplocephalidae) in northern cervids (alces and rangifer).phylogenetic relationships of tapeworms of the genus moniezia blanchard, 1891 (cestoda, anoplocephalidae) parasitizing the eurasian elk alces alces, the moose a. americanus and the reindeer/caribou rangifer tarandus (cervidae) were studied using dna sequences of two mitochondrial genes (cox1 and nad1). several isolates from domestic ruminants, representing moniezia expansa (rudolphi, 1810) sensu lato and m. benedeni (moniez, 1879) sensu lato, and one unidentified isolate from an african antelope ...201729288139
experimental life-cycle of varestrongylus eleguneniensis (nematoda: protostrongylidae) in a captive reindeer (rangifer tarandus tarandus) and a muskox (ovibos moschatus moschatus).the life-cycle of a recently described protostrongylid lungworm, varestrongylus eleguneniensis, which infects caribou, muskoxen, and moose from arctic and boreal regions of north america, was completed experimentally for the first time. a native north american slug species, deroceras laeve, was infected with the first-stage larvae (l1) isolated from the feces of wild muskoxen to generate third-stage larvae (l3). these were administered to a captive reindeer calf (250 l3) and an adult captive mus ...201728590168
relationship between general anesthesia and alzheimer disease: a protocol for a systematic review and meta-analysis.alzheimer disease (ad) entails a long-term progressive decline in the cognitive ability to think and remember, and it has become a major concern for patients receiving surgery and anesthesia. however, studies investigating the relationship between general anesthesia and ad have yielded inconsistent results. therefore, we plan to perform a systematic review and meta-analysis to determine the relationship between general anesthesia and ad, and to verify whether general anesthesia is an independent ...201729390504
influence of vitreomacular interface on anti-vascular endothelial growth factor treatment outcomes in neovascular age-related macular degeneration: a moose-compliant meta-analysis.the aim of the study was to evaluate the influence of vitreomacular interface configuration on treatment outcomes after intravitreal anti-vascular endothelial growth factor (anti-vegf) therapy for neovascular age-related macular degeneration (amd).the pubmed, embase, and cochrane central register of controlled trials databases were searched to identify relevant prospective or retrospective studies that evaluate the influence of vitreomacular adhesion (vma) or vitreomacular traction (vmt) on func ...201729390407
karyotype relationships among selected deer species and cattle revealed by bovine fish probes.the cervidae family comprises more than fifty species divided into three subfamilies: capreolinae, cervinae and hydropotinae. a characteristic attribute for the species included in this family is the great karyotype diversity, with the chromosomal numbers ranging from 2n = 6 observed in female muntiacus muntjak vaginalis to 2n = 70 found in mazama gouazoubira as a result of numerous robertsonian and tandem fusions. this work reports chromosomal homologies between cattle (bos taurus, 2n = 60) and ...201729112970
yew (taxus) intoxication in free-ranging cervids.wild ruminants, including deer species (cervids) have incorrectly been regarded as refractory to yew (taxus) intoxication. this assumption has been based upon anecdotal observations of individual deer browsing on yew over time without apparent adverse effect. a single case of yew intoxication was reported in a free-ranging norwegian moose (alces alces) in 2008. the current report describes five additional cases of yew toxicosis in moose, seven in roe deer (capreolus capreolus) and two in reindee ...201729281648
brominated flame retardants and toxic elements in the meat and liver of red deer (cervus elaphus), wild boar (sus scrofa), and moose (alces alces) from latvian wildlife.in order to evaluate the contamination status of terrestrial biota in latvia, muscle and liver tissues of red deer (cervus elaphus), wild boar (sus scrofa), and moose (alces alces) were analyzed for the content of polybrominated diphenyl ethers (pbde), hexabromocyclododecane (hbcd), tetrabromobisphenol a (tbbpa), as well as cadmium and lead. the highest mean concentrations of pbdes (46.6pgg-1 wet weight (w.w.)), cadmium (0.95mgkg-1 w.w.), and lead (0.22mgkg-1 w.w.) were observed in the tissues o ...201729202283
ante-mortem detection of chronic wasting disease in recto-anal mucosa-associated lymphoid tissues from elk (cervus elaphus nelsoni) using real-time quaking-induced conversion (rt-quic) assay: a blinded collaborative study.prion diseases are transmissible spongiform encephalopathies (tses) characterized by fatal, progressive neurologic diseases with prolonged incubation periods and an accumulation of infectious misfolded prion proteins. antemortem diagnosis is often difficult due to a long asymptomatic incubation period, differences in the pathogenesis of different prions, and the presence of very low levels of infectious prion in easily accessible samples. chronic wasting disease (cwd) is a tse affecting both wil ...201729098931
endemic chronic wasting disease causes mule deer population decline in wyoming.chronic wasting disease (cwd) is a fatal transmissible spongiform encephalopathy affecting white-tailed deer (odocoileus virginianus), mule deer (odocoileus hemionus), rocky mountain elk (cervus elaphus nelsoni), and moose (alces alces shirasi) in north america. in southeastern wyoming average annual cwd prevalence in mule deer exceeds 20% and appears to contribute to regional population declines. we determined the effect of cwd on mule deer demography using age-specific, female-only, cwd transi ...201729049389
climate warming is associated with smaller body size and shorter lifespans in moose near their southern range limit.despite the importance of body size for individual fitness, population dynamics and community dynamics, the influence of climate change on growth and body size is inadequately understood, particularly for long-lived vertebrates. although temporal trends in body size have been documented, it remains unclear whether these changes represent the adverse impact of climate change (environmental stress constraining phenotypes) or its mitigation (via phenotypic plasticity or evolution). concerns have al ...201729226555
spatio-temporal trends in crop damage inform recent climate-mediated expansion of a large boreal herbivore into an agro-ecosystem.large-scale climatic fluctuations have caused species range shifts. moose (alces alces) have expanded their range southward into agricultural areas previously not considered moose habitat. we found that moose expansion into agro-ecosystems is mediated by broad-scale climatic factors and access to high-quality forage (i.e., crops). we used crop damage records to quantify moose presence across the canadian prairies. we regressed latitude of crop damage against north atlantic oscillation (nao) and ...201729123188
state-dependent behavior alters endocrine-energy relationship: implications for conservation and management.glucocorticoids (gc) and triiodothyronine (t3) are two endocrine markers commonly used to quantify resource limitation, yet the relationships between these markers and the energetic state of animals has been studied primarily in small-bodied species in captivity. free-ranging animals, however, adjust energy intake in accordance with their energy reserves, a behavior known as state-dependent foraging. further, links between life-history strategies and metabolic allometries cause energy intake and ...201728777884
ninety-nine de novo assembled genomes from the moose (alces alces) rumen microbiome provide new insights into microbial plant biomass degradation.the moose (alces alces) is a ruminant that harvests energy from fiber-rich lignocellulose material through carbohydrate-active enzymes (cazymes) produced by its rumen microbes. we applied shotgun metagenomics to rumen contents from six moose to obtain insights into this microbiome. following binning, 99 metagenome-assembled genomes (mags) belonging to 11 prokaryotic phyla were reconstructed and characterized based on phylogeny and cazyme profile. the taxonomy of these mags reflected the overall ...201728731473
decline of heterozygosity in a large but isolated population: a 45-year examination of moose genetic diversity on isle royale.wildlife conservation and management approaches typically focus on demographic measurements to assess population viability over both short and long periods. however, genetic diversity is an important predictor of long term population vitality. we investigated the pattern of change in genetic diversity in a large and likely isolated moose (alces alces) population on isle royale (lake superior) from 1960-2005. we characterized samples, partitioned into five different 5-year periods, using nine mic ...201728729957
molecular detection of bartonella spp. in deer ked (lipoptena cervi) in poland.the bacteria of the genus bartonella are obligate parasites of vertebrates. their distribution range covers almost the entire world from america, europe, asia to africa and australia. some species of bartonella are pathogenic for humans. their main vectors are blood-sucking arthropods such as fleas, ticks and blood-feeding flies. one such dipteran able to transfer vector-borne pathogens is the deer ked (lipoptena cervi) of the family hippoboscidae. this species acts as a transmitter of bartonell ...201729037227
student experience at moose factory. 20174455660
sublethal lead exposure alters movement behavior in free-ranging golden eagles.lead poisoning of animals due to ingestion of fragments from lead-based ammunition in carcasses and offal of shot wildlife is acknowledged globally and raises great concerns about potential behavioral effects leading to increased mortality risks. lead levels in blood were correlated with progress of the moose hunting season. based on analyses of tracking data, we found that even sublethal lead concentrations in blood (25 ppb, wet weight), can likely negatively affect movement behavior (flight he ...201728414429
continental divide: predicting climate-mediated fragmentation and biodiversity loss in the boreal forest.climate change threatens natural landscapes through shifting distribution and abundance of species and attendant change in the structure and function of ecosystems. however, it remains unclear how climate-mediated variation in species' environmental niche space may lead to large-scale fragmentation of species distributions, altered meta-population dynamics and gene flow, and disrupted ecosystem integrity. such change may be especially relevant when species distributions are restricted either spa ...201728505173
whole-genome sequences of odocoileus hemionus deer adenovirus isolates from deer, moose and elk are highly conserved and support a new species in the genus atadenovirus.we present the first complete genome sequence of odocoileus hemionus deer adenovirus 1 (odadv-1). this virus can cause sporadic haemorrhagic disease in cervids, although epizootics with high mortality have occurred in california. odadv-1 has been placed in the genus atadenovirus, based on partial hexon, pviii and fibre genes. ten field isolates recovered from naturally infected mule deer (odocoileus hemionus), white-tailed deer (odocoileus virginiana) and moose (alces alces) from wyoming, black- ...201728809152
x chromosome evolution in cetartiodactyla.the phenomenon of a remarkable conservation of the x chromosome in eutherian mammals has been first described by susumu ohno in 1964. a notable exception is the cetartiodactyl x chromosome, which varies widely in morphology and g-banding pattern between species. it is hypothesized that this sex chromosome has undergone multiple rearrangements that changed the centromere position and the order of syntenic segments over the last 80 million years of cetartiodactyla speciation. to investigate its ev ...201728858207
the structure of the infectious prion protein and its propagation.the prion diseases, which include creutzfeldt-jakob disease in humans, chronic wasting disease in cervids (i.e., deer, elk, moose, and reindeer), bovine spongiform encephalopathy in cattle, as well as sheep and goat scrapie, are caused by the conversion of the cellular prion protein (prp(c)) into a disease-causing conformer (prp(sc)). prp(c) is a regular, gpi-anchored protein that is expressed on the cell surface of neurons and many other cell types. the structure of prp(c) is well studied, base ...201728838667
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