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comparison of nccls and 3-(4,5-dimethyl-2-thiazyl)-2, 5-diphenyl-2h-tetrazolium bromide (mtt) methods of in vitro susceptibility testing of filamentous fungi and development of a new simplified method.the susceptibility of 30 clinical isolates belonging to six different species of filamentous fungi (aspergillus fumigatus, aspergillus flavus, scedosporium prolificans, scedosporium apiospermum, fusarium solani, and fusarium oxysporum) was tested against six antifungal drugs (miconazole, voriconazole, itraconazole, ur9825, terbinafine, and amphotericin b) with the microdilution method recommended by the national committee for clinical laboratory standards (nccls) (m38-p). the mics were compared ...200010921957
localized skin infection due to scedosporium apiospermum: report of two cases. 199910583102
cutaneous scedosporium apiospermum infection in an immunocompromised patient.scedosporium apiospermum infection occurred in the left forearm of a patient who was taking oral prednisolone for pulmonary fibrosis. the infection appeared to follow a scratch from a blackcurrant bush. this is the first reported case in the united kingdom of a cutaneous infection from scedosporium apiospermum in an immunocompromised patient.199910690177
scedosporium apiospermum of the orbit. 199910037582
cutaneous infection with scedosporium apiospermum in a patient treated with corticosteroids. 199910494733
true fungal mycotic aneurysm of the basilar artery: a clinical and surgical dilemma.mycotic aneurysms of the intracranial circulation of true fungal etiology are extremely rare and are associated with a very high mortality. we report a case of a fatal aneurysm of the basilar artery secondary to scedosporium apiospermum infection. the medical and surgical treatments are presented to demonstrate the difficulties associated with these lesions.19999873163
comparison of e-test and broth microdilution methods for antifungal drug susceptibility testing of molds.we compared the e test with a broth microdilution method, performed according to national committee for clinical laboratory standards document m27-a guidelines, for determining the in vitro susceptibilities of 90 isolates of pathogenic molds (10 absidia corymbifera, 10 aspergillus flavus, 10 aspergillus fumigatus, 10 aspergillus niger, 10 aspergillus terreus, 10 exophiala dermatitidis, 10 fusarium solani, 10 scedosporium apiospermum, 5 scedosporium prolificans, and 5 scopulariopsis brevicaulis). ...199910203509
in vitro activity of syn-2869, a novel triazole agent, against emerging and less common mold pathogens.the in vitro activity of syn-2869 was compared with that of amphotericin b and itraconazole. mics for 100 isolates of pathogenic molds belonging to 12 species were determined by a broth microdilution adaptation of the method recommended by the national committee for clinical laboratory standards. syn-2869 and itraconazole showed comparable, good activity against the dematiaceous molds cladophialophora bantiana, cladophialophora carrionii, exophiala dermatitidis, fonsecaea pedrosoi, phialophora p ...199910223947
comparative in-vitro activity of voriconazole (uk-109,496) and six other antifungal agents against clinical isolates of scedosporium prolificans and scedosporium apiospermum.we report the in-vitro susceptibility of 27 clinical isolates of scedosporium apiospermum and 43 of scedosporium prolificans. s. apiospermum was resistant to fluconazole and flucytosine, with variable susceptibility to amphotericin b, itraconazole, ketoconazole and susceptible to miconazole. voriconazole was much more active than fluconazole and flucytosine, more active than amphotericin b, itraconazole and ketoconazole and was as active as miconazole against s. apiospermum isolates. voriconazol ...199910381115
fatal native valve endocarditis due to scedosporium apiospermum (pseudallescheria boydii) following trauma. 199910421053
invasive fungal sinusitis due to scedosporium apiospermum in a patient with aids. 199910433595
peritonitis by scedosporium apiospermum in a patient undergoing continuous ambulatory peritoneal dialysis.a case of peritonitis due to scedosporium apiospermum in a boy undergoing continuous ambulatory peritoneal dialysis is reported. the finding of suggestive tissual form of the fungus in the effluent hastened the diagnosis of the infection.199910564923
biodegradation of phenylbenzoate and some of its derivatives by scedosporium apiospermum.scedosporium apiospermum, a recently isolated phenol-degrading hyphomycete, was shown to be able to productively utilise the diaryl ester phenylbenzoate as its sole source of carbon and energy. the characterisation of degradation intermediates together with the detection of the corresponding catabolic enzymes in crude extracts enabled us to propose a pathway for the degradation of this diaryl ester. according to our results, an inducible esterase initiated the biodegradation of phenylbenzoate by ...199910466410
[scedosporium apiospermum external otitis.].we report a case of scedosporium apiospermum external otitis. the patient was topically treated with miconazole cream and achieved a clinical and mycological cure. the etiology, diagnosis and treatment of external fungal otitis are discussed.199918473567
onychomycosis in white line disease in horses: pathology, mycology and clinical features.this paper describes onychomycosis in horses and reports the pathological findings, associated fungi and incidence of concurrent white line disease. in addition to these observations, relevance between post mortem and clinical findings of onychomycosis are discussed in 3 necropsied horses. samples were collected from 100 hooves from a total of 51 thoroughbreds suffering from white line disease. of these, 15 hooves from 13 horses were also complicated with severe hoof wall fissure formation. prep ...19989932091
scedosporium apiospermum sinusitis after bone marrow transplantation: report of a case.a forty-year-old man underwent an allogeneic bmt from his hla identical sister. gvhd prophylaxis was done with cyclosporine (cya), methotrexate and prednisone (pdn). on day +90 extensive gvhd was noted and higher doses of immunosuppressive drugs alternating cya with pdn were initiated. patient's follow-up was complicated by intermittent episodes of leukopenia and monthly episodes of sinusitis or pneumonia. one year after bmt, the patient developed hoarseness and nasal voice. no etiologic agent c ...199810030078
[rare pulmonary mycoses in patients with hematologic diseases].patients with hematology disease in post-chemotherapy medullary aplasia are susceptible to life-threatening bronchopulmonary mycoses, especially aspergillosis. other less common pulmonary mycoses are also observed. we report 4 cases due to penicillium purpurogenum, acromonium strictum and scedosporium apiospermum (n = 2) infections. these unusual fungi appear to be emerging as pathogens in this population. they have common ubiquitous, opportunistic and low pathogenicity characteristics in immuno ...19989894280
pulmonary scedosporiosis.a case of a solitary pulmonary nodule due to scedosporium apiospermum (pseudallescheria boydii) is related. a review of the pertinent literature was done and, in addition, similar lesions caused by other opportunistic fungi are commented.19989876438
nasal granuloma caused by scedosporium apiospermum in a dog.a 10-month-old male american staffordshire terrier was presented to the autonomous university of barcelona veterinary teaching hospital because of a 6-month history of a mucopurulent bilateral nasal discharge. the dog had not responded to antibiotics. a follow-up x ray revealed a mixed pattern of osteolysis and increased radiodensity confined to the nasal cavity. histologic sections of the biopsy specimens revealed the presence of granules containing numerous septate hyphae that were hyaline to ...19989705431
scedosporium apiospermum skin infection: a case report and review of the literature. 19989738792
polypoid bronchial lesions due to scedosporium apiospermum in a patient with mycobacterium avium complex pulmonary disease.a 69 yr old female was hospitalized for further examination of abnormal shadows on chest radiographs. she had a history of tuberculous pleurisy, rheumatoid arthritis and gold-induced interstitial pneumonia. on admission she still suffered from rheumatoid arthritis. a chest computed tomography scan on admission showed clusters of small nodules in subpleural regions of both lungs combined with bronchiectasis. mycobacterium avium complex was cultured repeatedly from the sputum. bronchoscopic examin ...19989762808
[sensitivity to disinfectants in certain rare micromycetes].the authors investigated the effectiveness of 6 different disinfectants at recommended concentrations on strains of rare types of filamentous micromycetes: scedosporium apiospermum and exophiala dermatitidis (isolated from ophthalmomycoses), fusarium dimerum (isolates from nosocomial fungaemia) and strains of fusarium moniliforme and stachybotrys alternans (isolates from the environment and potential producers of mycotoxins). the tested strains were mostly sensitive also to an alcoholic solution ...19989611894
pcr-based identification of clinically relevant pseudallescheria/scedosporium strains.pseudallescheria boydii (anamorph: scedosporium apiospermum) and s. prolificans can cause severe infections in both the immunocompromized host and accidentally injured people. a species-specific polymerase chain reaction (pcr) enabling detection and discrimination of these fungi has not been available to date. in view of the difficult treatment especially of s. prolificans infections, a pcr-based detection system has been developed. based on results of partial sequencing of ribosomal dna, scedos ...19989776815
scedosporium apiospermum (pseudallescheria boydii) infection in a heart transplant recipient: a case of mistaken identity.we report a case of fatal central nervous system infection with scedosporium apiospermum (pseudallescheria boydii) in a heart transplant recipient. this ubiquitous fungus is known to cause mycetoma and localized infections in patients with otherwise normal conditions. disseminated infections occur rarely and are seen primarily in patients who are receiving immunosuppressive medications or who have neutropenia. often life-threatening when infection is disseminated and involves the central nervous ...19989563611
use of voriconazole in treatment of scedosporium apiospermum infection: case report.we report a case of disseminated scedosporium apiospermum infection in a neutropenic patient with acute myeloid leukemia. due to progression of the mycosis after 7 days of amphotericin b lipid complex therapy and to high susceptibility of the mold to voriconazole in vitro, the patient was treated with intravenous voriconazole. after a few days of therapy, fever disappeared and skin lesions improved. however, the patient died after 1 month due to intestinal bleeding. despite a negative outcome, t ...19989574724
[cutaneous scedosporium infection revealed by bullous-necrotic purpura].non-mycetomatous cutaneous scedosprium is an uncommon mycosis observed in immunodepressed subjects. we report a case with an inaugural presentation of bullous and necrotic purpura.19989835962
invasive pulmonary infection due to scedosporium apiospermum in two children with chronic granulomatous disease.scedosporium apiospermum is an opportunistic fungus in humans. the incidence of s. apiospermum infection in patients with acquired neutropenia (e.g., patients receiving chemotherapy and bone marrow transplant recipients) is steadily increasing. s. apiospermum has poor in vitro susceptibility to "conventional" antifungal agents, rendering the management of infections complex. patients with chronic granulomatous disease (cgd) are highly susceptible to fungal infections, which are mostly due to asp ...19989868657
in-vitro activity of voriconazole, itraconazole and amphotericin b against filamentous fungi.the in-vitro fungistatic and fungicidal activities of voriconazole were compared with those of itraconazole and amphotericin b. mics for 110 isolates belonging to 11 species of filamentous fungi were determined by a broth microdilution adaptation of the method recommended by the national committee for clinical laboratory standards. minimum lethal concentrations (mlcs) of the three antifungal agents were also determined. the mic ranges of the three compounds were comparable for aspergillus flavus ...199810052897
pathology of hyalohyphomycosis caused by scedosporium apiospermum (pseudallescheria boydii): an emerging mycosis.the genus scedosporium contains two medically significant species of emerging mycotic agents, s. apiospermum and s. prolificans, which have received scant attention. scedosporium apiospermum is the anamorph, or asexual state, of the cosmopolitan fungus pseudallescheria boydii, with both sharing the same risk factors for infection, clinical spectrum, and histopathologic features. scedosporium prolificans is a recently recognized agent of bone, soft tissue, and joint infections that occurs with hi ...19989824105
biodegradation of phenol and p-cresol by the hyphomycete scedosporium apiospermum.a hyphomycete with the ability to utilize phenol and p-cresol as carbon and energy source was isolated from soil and subsequently identified as scedesporium apiospermum. the identification of degradation metabolites and the detection of the corresponding catabolic enzymes in crude extracts enabled us to propose different pathways for the degradation of both phenol and p-cresol in this organism. generally, the catabolism proceeded via three different dihydroxylated intermediates (catechol, hydrox ...19989766239
subcutaneous scedosporiosis. report of two cases and review of the literature.two cases of subcutaneous scedosporiosis, caused by scedosporium apiospermum, are reported. both patients had lesions localized in the forearm: a solitary ulceration in one and a sporotrichoid-like lesion in the other. the literature is reviewed.19979640787
cutaneous infection by scedosporium apiospermum and its successful treatment with itraconazole.we report the case of a 42-year-old man with a 13-year history of bilateral faciocervical infiltrative erythema, which had been misdiagnosed as tuberculoderma and which had failed to respond to treatment with adrenal corticosteroids and antituberculotics. on admission to the department, scedosporium apiospermum was identified on lesion biopsies and fungus cultures as the causative agent and a diagnosis of cutaneous infection by s. apiospermum was made. this is the first report of chronic skin gr ...19979499613
scedosporium apiospermum skin infection in a patient with nephrotic syndrome. 19979111845
pulmonary tuberculosis associated with invasive pseudallescheriasis.a 54-year-old woman with pulmonary tuberculosis developed pneumonia caused by scedosporium apiospermum, the asexual stage of the fungus pseudallescheria boydii. mycobacterium tuberculosis and p boydii were cultured in bal fluid. the patient cleaned swimming pools in a spa health resort and was highly exposed to fungal conidia. she was successfully treated with antituberculosis drugs, miconazole nitrate and ketoconazole, leading to remission of her pulmonary infection. invasive pulmonary pseudall ...19979042007
in vitro studies of activity of voriconazole (uk-109,496), a new triazole antifungal agent, against emerging and less-common mold pathogens.the in vitro activity of voriconazole was compared with that of itraconazole. eighty-six isolates of pathogenic molds belonging to 23 species were tested by an agar dilution method in high resolution medium. voriconazole was more active than itraconazole against a number of hyaline molds, including several fusarium spp. and scedosporium prolificans. voriconazole and itraconazole showed comparable good activity against several hyaline molds, including penicillium marneffei and scedosporium apiosp ...19979087501
in vitro antifungal activity of pneumocandin l-743,872 against a variety of clinically important molds.the in vitro activity of the new antifungal drug pneumocandin l-743,872 against 55 isolates of clinically important molds was examined by an adapted macrobroth dilution method for yeasts. pneumocandin l-743,872 exhibited in vitro antifungal activity against alternaria sp., aspergillus flavus, aspergillus fumigatus, curvularia lunata, exophiala jeanselmei, fonsecaea pedrosoi, paecilomyces variotii, and scedosporium apiospermum. the drug appeared to lack significant in vitro inhibitory activity ag ...19979257774
deep infections caused by scedosporium prolificans. a report on 16 cases in spain and a review of the literature. scedosporium prolificans spanish study group.scedosporium prolificans, a mold morphologically similar to scedosporium apiospermum, may cause asymptomatic colonization or localized or disseminated infection following trauma, surgery, and immunosuppression. s. prolificans is normally resistant to available antifungal agents, and prognosis depends largely on the host's immune status, extent of infection, and feasibility of surgical debridement. we report on 16 patients with deep s. prolificans infections, focusing on predisposing factors, cli ...19979279332
new polyazole derivatives from 2-(2,4-dichlorophenyl)-1,3-dioxolane. antifungal activity. structure-activity relationships.six new polyazole derivatives from 2-(2,4-dichlorophenyl)-1,3-dioxolane were studied for their antifungal activity against pathogenic fungi for humans and animals. the antimycotic effect was largely restricted to the filamentous fungi with aspergillus fumigatus and scedosporium apiospermum being remarkably susceptible. three compounds were as effective as the two references, ketoconazole and oxiconazole. the structure-activity relationships revealed than an 'oxime group' combined with four chlor ...19979299755
lymphocutaneous infection due to scedosporium apiospermum. 19979352411
[mycotic keratitis with uveitis cause by scedosporium apiospermum].mycotic keratitis with induced uveitis caused by scedosporium apiospermum. in the work the case of mycotic keratitis with induced uveitis is descriped. affected is young healthy woman working in a fruit and vegetable store. affection arised on cornea in the area of previous erosion. current antibiotics did not have any effect on the affection after repeated negative cultivative examinations. the culture of fibrous mikromycete was gained out of cultivation done on sabouraud's glucose agar and was ...19979377319
amphotericin b responsive scedosporium apiospermum infection in a patient with acute myeloid leukaemia.a 71 year old man with newly diagnosed acute myelomonocytic leukaemia developed a soft tissue infection of his foot during his first course of chemotherapy. scedosporium apiospermum was isolated from the lesion, which resolved rapidly on treatment with intravenous amphotericin b despite being resistant in vitro to this agent. this observation suggests that sensitivity testing of s apiospermum should be interpreted with caution and that clinical response may be a better indicator of outcome.19968666698
a 33 kda serine proteinase from scedosporium apiospermum.an extracellular proteinase produced by the filamentous fungus scedosporium apiospermum has been purified and characterized. initially, in vitro conditions for enzyme synthesis were investigated. the highest yield of enzyme production was obtained when the fungus was cultivated in modified czapek-dox liquid medium supplemented with 0.1% bacteriological peptone and 1% (w/v) glucose as the nitrogen and carbon sources respectively. purification to homogeneity of the proteinase was accomplished by ( ...19968670095
scedosporium apiospermum pneumonia after autologous bone marrow transplantation.although opportunistic infections after bone marrow transplantation (bmt) are very common, only five cases of pseudallescheria boydii infection have been reported in the literature, two of which were autopsy findings. a case of scedosporium apiospermum infection after bmt, treated initially with amphotericin b (total dose of 2.5 g) and then with itraconazole (for 25 days), is reported here. when the patient failed to improve, scedosporium apiospermum pneumonia was diagnosed and therapy was chang ...19968874080
development of murine monoclonal antibodies for the immunohistochemical diagnosis of systemic bovine aspergillosis.murine monoclonal antibodies (mabs) against water-soluble somatic antigens (wssa) and the wall fraction (wf) from aspergillus fumigatus were produced by fusion of splenocytes from immunized balb/c mice with mouse myeloma x63-ag 8.653 cells. the supernatants of in vitro cultured hybridomas were initially screened for reactivity with the wssa and the wf from a. fumigatus and wssa of other fungi in an enzyme-linked immunosorbent assay (elisa). supernatants reacting only with a. fumigatus antigens w ...19969026084
[epidemiology of invasive mycoses. experience of a university hospital center in paris].the incidence of opportunistic fungal infections have dramatically increased during the past decades. data from a retrospective study conducted between january 1992 and december 1994 in necker-enfants malades hospital and a review of the literature were analyzed to assess the main epidemiological features of these infections. candidiasis remained largely the most frequent: candidemia and invasive candidiasis were diagnosed in respectively 71 and 11 patients. candida albicans was the agent the mo ...19968959131
scedosporium apiospermum infection imitating lymphocutaneous sporotrichosis in a patient with myeloblastic-monocytic leukaemia.a 63-year-old man with a history of myeloblastic-monocytic leukaemia developed partly suppurating cutaneous nodules on the lower left leg. the nodules proceeded to spread in a linear fashion up the limb, following the line of the lymphatic drainage. mycological examination of a skin biopsy demonstrated scedoporium apiospermum. this case highlights the potential for scedosporium species to act as opportunistic infections in immunosuppressed humans.19958555041
cerebral pseudallescheria mycosis after near-drowning.scedosporium apiospermum, an anamorph of pseudallescheria boydii, is a hyalohyphomycete which can be mistaken, histologically, for aspergillus. s. apiospermum is clinically distinguished by resistance to most antifungals and its ability to cause invasive mycoses in immunocompetent patients. here we present a typical case of lethal cerebral pseudallescheria mycosis in a child after near-drowning.19958720198
ribosomal dna internal transcribed spacer analysis supports synonomy of scedosporium inflatum and lomentospora prolificans.scedosporium inflatum is a dematiaceous opportunistic pathogen originally described by d. malloch and i.f. salkin (mycotaxon 21:247-255, 1984). however, e. gueho and g. s. de hoog (j. mycol. med. 118:3-9, 1991) recently suggested reducing this mold to synonomy with lomentospora prolificans on the basis of their similar morphological and molecular characteristics. we have investigated the ribosomal dna internal transcribed spacers (its), i.e., its i and its ii, of 18 isolates, including these two ...19947814476
phylogeny of dermatophytes and dimorphic fungi based on large subunit ribosomal rna sequence comparisons.the phylogeny of dermatophytes and dimorphic fungi was considered using the large-subunit of ribosomal rna (25s rrna). aligned sequences of 595 nucleotides covering the two most divergent domains d1 and d2, permitted a comparison of phylogenetic relationships at different levels. the dimorphic species (onygenaceae) were significantly separated from dermatophytes (arthrodermataceae) and from a third group including geophilic or very weakly pathogenic species (onygenaceae and gymnoascaceae). on a ...19947844699
successful bone marrow transplantation in patients with previous invasive fungal infections: report of four cases.patients with previous invasive fungal infections (ifi) are at high risk of reactivation of the infection during bmt, even after an apparently curative antifungal treatment. we report four patients who suffered an ifi after intensive chemotherapy for acute leukemia and were later submitted for bmt. one patient had developed a chronic systemic candidiasis during consolidation chemotherapy and received prophylactic oral or iv fluconazole (200 mg daily) throughout bmt. two patients developed an inv ...19948199569
fungal arthritis due to pseudallescheria boydii (scedosporium apiospermum).musculoskeletal infections by fungal agents are uncommon conditions. pseudallescheria boydii is an ubiquitous saprophytic fungus frequently involved in maduromycosis but rarely in septic arthritis. we describe a case of pseudallescheria boydii destructive suppurative arthritis and osteomyelitis of the knee in an adult guadeloupean man. osteoarticular infections due to pseudallescheria boydii are reviewed.19948035409
[scedosporium apiospermum infection in a patient with myelomonocytic leukemia presenting as lympho-cutaneous sporotrichosis].63 year old patient is presented with myelo-monocytic leukemia, in whom subcutaneous nodules developed at the lower limb, spreading along the lymph vessels, and partly ulcerating. by mycologic investigation scedosporium apiospermum was disclosed. attention is drawn to human infections brought about by opportunistic scedosporium species.19947970657
fungal panophthalmitis secondary to scedosporium apiospermum (pseudallescheria boydii) keratitis. 19947943139
[severe keratomycosis. diagnosis and treatment].we reported three consecutive cases of severe fungal keratitis initially undiagnosed by corneal scrapping. corneal biopsy showed fungal elements of paecilomyces lilacinus, fusarium solani, scedosporium apiospermum. most cases of fungal keratitis could be treated successfully if adequate antifungal therapy were started early. early and accurate diagnosis is of major importance. the results of our cases confirm the superiority of corneal biopsy over corneal scrapping. corneal biopsy is a procedure ...19947822693
fungal mycotic aneurysms and visceral infection due to scedosporium apiospermum in a kidney transplant patient. 19938516902
successful treatment of pneumonia due to scedosporium apiospermum with itraconazole: case report. 19938389611
[disseminated infection due to scedosporium apiospermum in liver transplantation. differential diagnosis from invasive aspergillosis].a case of fatal disseminated infection due to scedosporium apiospermum occurring after liver transplantation is reported. diagnosis was made at autopsy, as numerous fungal colonies were found in the lungs, heart, brain, kidney, spleen and liver. scedosporium apiospermum was identified in pulmonary, cerebral and myocardial specimens by sabouraud's glucose agar cultures. infections due to scedosporium (s. apiospermum ou pseudallescheria boydii) occur in immunocompromised hosts, particularly after ...19938311860
mycetoma: a retrospective study of 41 cases seen in são paulo, brazil, from 1978 to 1989.clinical and epidemiological aspects of 41 cases of mycetoma seen in são paulo city from january 1978 to december 1989 are presented. twenty-eight cases (68%) were caused by actinomycetes, while 13 (32%) were caused by true fungi. in only 22 (78%) actinomycetoma cases was it possible to identify the agent. nocardia brasiliensis, by far the commonest actinomycete isolated, was responsible for 13 cases. among eumycetomata, madurella grisea was isolated from 3 cases, scedosporium apiospermum from 2 ...19938366881
clinical features of human infection with scedosporium inflatum.we report on 17 australian cases of human infection or colonization with scedosporium inflatum. the spectrum of clinical manifestations was similar to that in infection caused by scedosporium apiospermum. the patients were classified into three groups. four immunocompetent patients who presented with localized infections of a joint, nail bed, eye, or sphenoidal sinus made up the first group. our first case, in a boy with posttraumatic septic arthritis, responded to surgical drainage with amphote ...19921534693
[apropos of 2 cases of scedosporium apiospermum nasosinusal infection].we report two cases of nasosinusal infection caused by scedosporium apiospermum and involving the nasal fossa in one case and the maxillary sinus in the other. the course of the disease varied according to the patient's immune status. the otherwise healthy patient (case n. 1) was completely cured by surgery, whereas the immunosuppressed patient (case n. 2) had local extension with pseudotumoral symptoms and lysis of the inter-sinusonasal septum; an early surgical treatment combined with local ad ...19921410889
experimental infection with scedosporium inflatum.the experimental pathogenicity of scedosporium inflatum (three isolates) and scedosporium apiospermum (one strain) was determined following intraperitoneal and intravenous injection into immunosuppressed and normal mice. immunosuppressed animals were treated with cortisone acetate. the results show that the strains studied displayed positive tropism to kidney and brain. in the histopathological study of the first organ, we initially observed abscesses at the glomerular level and later in the ren ...19921287160
[fungus-induced arthritis caused by scedosporium apiospermum (pseudallescheria boydii)].scedosporium (monosporium) apiospermum is the most common causative agent of maduro mycosis. recent research reports claim that this fungus can also induce arthritis. we report on the disease in a woman from a rural area who was admitted to our clinic because of arthritis symptoms. we were able to detect scedosporium apiospermum, i.e., it was probably a fungus-induced arthritis which had developed after an intraarticular steroid injection.19911746172
keratomycosis due to scedosporium apiospermum.although no overt injury occurred, a corneal abscess without hypopyon developed in a normal, 25-year-old female, living in a suburban area of madrid, following a period of intensive garden work. direct examination of the corneal scrapings on one occasion showed septate, branched hyphal elements. when scrapings were cultured on sabouraud glucose and brain heart infusion agars a pure culture of scedosporium apiospermum was repeatedly isolated. the patient responded successfully to treatment with m ...19911824418
successful treatment of scedosporium apiospermum suppurative arthritis with itraconazole. 19902172910
the first case of pseudallescheria boydii meningitis in china--electron microscopic study and antigenicity analysis of the agent.reported in this paper is the first case of isolation of pseudallescheria boydii from cerebral spinal fluid of a boy with meningitis in china. morphology and culture were observed by light microscopy, electron scanning microscopy and transmission electron microscopy. in addition, mycelium antigen prepared by sds-page was compared with that of the other strain of scedosporium apiospermum. both of the strains showed more than 40 peptide lines. their molecular weight was very similar. on the cs-930 ...19902098578
[clinical case of mycetoma caused by scedosporium apiospermum].the authors report a case of mycetoma from scedosporium apiospermum in a 19 years old patient affected by adult's cgd. they emphasize the importance of mycetes' identification from clinical specimens' isolates, to consent a correct interpretation of the bacteriological result from physician.19892490408
potted plants in hospitals as reservoirs of pathogenic fungi.the soils of five potted plants cultivated within a hospital were investigated for the presence of fungal opportunistic pathogens of humans. a total of 16 potentially pathogenic species were isolated, including aspergillus fumigatus at up to 53.5 colony-forming units (cfu) per gram dry soil and scedosporium apiospermum (pseudallescheria boydii) at up to 97.0 cfu/g. other common species included phialophora verrucosa and fusarium solani. scedosporium inflatum, a recently described emerging pathog ...19892671744
[a case of prosthetic valve endocarditis due to scedosporium apiospermum]. 19892732604
scedosporium inflatum, an emerging pathogen.the salient morphologic and physiologic characteristics of 18 isolates of scedosporium inflatum, a newly reported human pathogen, were compared with those of the morphologically similar fungi scedosporium apiospermum, scopulariopsis brevicaulis, and scopulariopsis brumptii. the formation by s. inflatum of annelloconidia in wet clumps at the apices of annellides with swollen bases was found to be the most useful characteristic in differentiating this potential pathogen.19883356789
a case of disseminated scedosporium apiospermum infection after bone marrow transplantation. 19873295538
[cutaneous microabscesses caused by scedosporium apiospermum]. 19852931685
[fungal mycotic aneurysms and multiple cerebral abscesses caused by scedosporium apiospermum. apropos of a case with review of the literature].the authors report a case of intracranial fungal aneurysm and brain abscesses. the compromised host was a young drowned woman. scedosporium apiospermum was isolated in fungal culture from abscess. radiological and clinical pictures are typical of the hyphal form.19853839532
an atypical isolate of scedosporium apiospermum from a purulent meningitis in man. 19817197398
annellated conidiogenous cells in petriellidium boydii (scedosporium apiospermum).annellated conidiogenous cells of both the mononematous (scedosporium state) and synnematous (graphium state) conidiophores develop in the conidial state of petriellidium (= allescheria) boydii, scedosporium (= monosporium) apiospermum. conidiogenesis in this species is characterized by percurrent proliferation of the conidiogenous cells and the conidia are holoblastic and annellidic.19807455859
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