Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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| draft genome and reference transcriptomic resources for the urticating pine defoliator thaumetopoea pityocampa (lepidoptera: notodontidae). | the pine processionary moth thaumetopoea pityocampa (lepidoptera: notodontidae) is the main pine defoliator in the mediterranean region. its urticating larvae cause severe human and animal health concerns in the invaded areas. this species shows a high phenotypic variability for various traits, such as phenology, fecundity, and tolerance to extreme temperatures. this study presents the construction and analysis of extensive genomic and transcriptomic resources, which are an obligate prerequisite ... | 2018 | 29352511 |
| pelvic floor muscle function and quality of life in post-menopausal women with and without pelvic floor dysfunction. | this study aims to compare pelvic floor muscle (pfm) function in post-menopause women with and without pelvic floor dysfunction (pfd) and the relationship between pfm function and quality of life material and methods: a case-control study with 216 post-menopause women with (n=126) and without pfd (n=90). pfm function was assessed by digital vaginal palpation using perfect scale. specific quality of life was evaluated by king's health questionnaire for women with urinary incontinence and prolapse ... | 2018 | 29352460 |
| polyhydroxybutyrate (phb) synthesis by spirulina sp. leb 18 using biopolymer extraction waste. | the reuse of waste as well as the production of biodegradable compounds has for years been the object of studies and of global interest as a way to reduce the environmental impact generated by unsustainable exploratory processes. the conversion of linear processes into cyclical processes has environmental and economic advantages, reducing waste deposition and reducing costs. the objective of this work was to use biopolymer extraction waste in the cultivation of spirulina sp. leb 18, for the cycl ... | 2018 | 29352458 |
| myocardial perfusion in patients with suspected coronary artery disease: comparison between 320-mdct and rubidium-82 pet. | despite advances in non-invasive myocardial perfusion imaging (mpi) evaluation, computed tomography (ct) multiphase mpi protocols have not yet been compared with the highly accurate rubidium-82 positron emission tomography (82rbpet) mpi. thus, this study aimed to evaluate agreement between 82rbpet and 320-detector row ct (320-ct) mpi using a multiphase protocol in suspected cad patients. | 2018 | 29352381 |
| tracking the evolution of transiently transfected individual cells in a microfluidic platform. | transient gene expression (tge) technology enables the rapid production of large amount of recombinant proteins, without the need of fastidious screening of the producing cells required for stable transfection (st). however, several barriers must be overcome before reaching the production yields using st. for optimizing the production yields from suspended cells using tge, a better understanding of the transfection conditions at the single cell level are required. in this study, a universal drop ... | 2018 | 29352253 |
| the 'forma specialis' issue in fusarium: a case study in fusarium solani f. sp. pisi. | the fusarium solani species complex (fssc) has been studied intensively but its association with legumes, particularly under european agro-climatic conditions, is still poorly understood. in the present study, we investigated phylogenetic relationships and aggressiveness of 79 isolates of the fssc collected from pea, subterranean clover, white clover and winter vetch grown under diverse agro-climatic and soil conditions within temperate and mediterranean europe. the isolates were characterized b ... | 2018 | 29352160 |
| blocking zika virus vertical transmission. | the outbreak of the zika virus (zikv) has been associated with increased incidence of congenital malformations. although recent efforts have focused on vaccine development, treatments for infected individuals are needed urgently. sofosbuvir (sof), an fda-approved nucleotide analog inhibitor of the hepatitis c (hcv) rna-dependent rna polymerase (rdrp) was recently shown to be protective against zikv both in vitro and in vivo. here, we show that sof protected human neural progenitor cells (npc) an ... | 2018 | 29352135 |
| comparative transcriptomic and proteomic analysis of arthrobacter sp. cgmcc 3584 responding to dissolved oxygen for camp production. | arthrobacter sp. cgmcc 3584 is able to produce high yields of extracellular cyclic adenosine monophosphate (camp), which plays a vital role in the field of treatment of disease and animal food, during aerobic fermentation. however, the molecular basis of camp production in arthrobacter species is rarely explored. here, for the first time, we report the comparative transcriptomic and proteomic study of arthrobacter cells to elucidate the higher productivity of camp under high oxygen supply. we fi ... | 2018 | 29352122 |
| cryptic production of trans-3-hydroxyproline in echinocandin b biosynthesis. | echinocandins are antifungal nonribosomal hexapeptides produced by fungi. two of the amino acids are hydroxy-l-prolines: trans-4-hydroxy-l-proline and, in most echinocandin structures, (trans-2,3)-3-hydroxy-(trans-2,4)-4-methyl-l-proline. in the case of echinocandin biosynthesis by glarea lozoyensis, both amino acids are found in pneumocandin a0, while in pneumocandin b0 the latter residue is substituted by trans-3- hydroxy-l-proline (3-hyp). we have recently reported that all three amino acids ... | 2018 | 29352089 |
| cardiac biomarkers as sensitive tools to evaluate the impact of xenobiotics on amphibians: the effects of anionic surfactant linear alkylbenzene sulfonate (las). | amphibian populations have been experiencing a drastic decline worldwide. aquatic contaminants are among the main factors responsible for this decline, especially in the aquatic environment. the linear alkylbenzene sulfonate (las) is of particular concern, since it represents 84% of the anionic surfactants' trade. in brazil, the maximal las concentration allowed in fresh waters is 0.5mgl-1, but its potential harmful effects in amphibians remain unknown. therefore, this study aimed to analyze the ... | 2018 | 29351853 |
| out-of-field doses in children treated for large arteriovenous malformations using hypofractionated gamma knife radiosurgery and intensity-modulated radiation therapy. | the purpose of this study was to measure out-of-field organ doses in two anthropomorphic child phantoms for the treatment of large brain arteriovenous malformations (avms) using hypofractionated gamma knife (gk) radiosurgery and to compare these with an alternative treatment using intensity-modulated radiation therapy (imrt). target volume was identical in size and shape in all cases. radiophotoluminescent (rpl), thermoluminescent (tl) and optically stimulated luminescent (osl) dosimeters were u ... | 2018 | 29351691 |
| molecular characterization and expression profiles of sp-uchl3 and sp-uchl5 during gonad development of scylla paramamosain. | ubiquitin c-terminal hydrolases (uchls) are a subset of deubiquitinating enzymes, and are involved in numerous physiological processes. however, the role of uchls during gonad development has not been studied in crustaceans. in this study, we have first cloned and analyzed expression profiling of sp-uchl3 and sp-uchl5 genes from mud crab scylla paramamosain. the full-length cdna of sp-uchl3 is of 1804 bp. its expression level in the ovary was significantly higher than in other tissues (p < 0.01) ... | 2018 | 29351241 |
| seed endophyte microbiome of crotalaria pumila unpeeled: identification of plant-beneficial methylobacteria. | metal contaminated soils are increasing worldwide. metal-tolerant plants growing on metalliferous soils are fascinating genetic and microbial resources. seeds can vertically transmit endophytic microorganisms that can assist next generations to cope with environmental stresses, through yet poorly understood mechanisms. the aims of this study were to identify the core seed endophyte microbiome of the pioneer metallophyte crotalaria pumila throughout three generations, and to better understand the ... | 2018 | 29351192 |
| fatigue failure of external hexagon connections on cemented implant-supported crowns. | to evaluate the probability of survival and failure modes of different external hexagon connection systems restored with anterior cement-retained single-unit crowns. the postulated null hypothesis was that there would be no differences under accelerated life testing. | 2018 | 29351113 |
| two nematode species from freshwater and marine fishes in thailand, including ascarophis scatophagi sp. nov. (cystidicolidae) from scatophagus argus (scatophagidae). | one new and one known species of parasitic nematodes are reported from thailand for the first time: falcaustra kaverii (karve et naik,1951) (kathlaniidae) from the intestine of the freshwater fish poropuntius deauratus (valenciennes) (cyprinidae) (new host record) and ascarophis scatophagi sp. nov. (cystidicolidae) from the intestine of the marine fish scatophagus argus (linnaeus) (scatophagidae). the morphology of both these species was studied with the use of light (lm) and scanning electron m ... | 2018 | 29351074 |
| a new species of aplectana (nematoda, cosmocercidae) in goniurosaurus bawanglingensis (squamata, eublepharidae), from hainan province, china. | aplectana hainanensis sp. nov. (ascaridida, cosmocercidae) from the intestines of goniurosaurus bawanglingensis (squamata, eublepharidae) is described and illustrated. aplectana hainanensis sp. nov. represents the 52nd species assigned to the genus and the 5th species reported from the sino-japanese region. it is easily separated from the 4 species previously reported from the region by the distribution pattern of male caudal papillae: a. macintoshii has an irregular pattern; a. hylae has no pre ... | 2018 | 29351068 |
| nematode parasites of duttaphrynus stomaticus (lutken, 1864) (amphibia: anura) with description of a new species of rhabdias stiles and hassall, 1905 (nematoda: rhabdiasidae) from dehradun (uttarakhand), india. | rhabdias stomatica sp. nov. from the lungs of duttaphrynus stomaticus (lutken, 1864) from dehradun, uttarakhand, india is described and illustrated. rhabdias stomatica sp. nov. is the 16th species described from the oriental biogeographical region and the 8th species from india. the new species is differentiated from the closely related oriental species in having 4 weakly developed lips, a trapezoidal shaped buccal cavity, different position of nerve ring and in the esophagus/body length ratio. ... | 2018 | 29351060 |
| three dimensional porous sic for lithium polysulfide trapping. | one of the key issues in lithium sulfur batteries is the fast capacity fade induced by the lithium polysulfide (lips) migration. hence, a series of three-dimensional (3d) porous sic materials with active sp2 si atoms have been designed for lithium polysulfide entrapping in li-s batteries. the zgm-sic-1 and agm-sic-3 have been confirmed to be thermodynamically and dynamically stable from the formation energy and phonon dispersion spectrum, meanwhile showing good mechanical properties. the moderat ... | 2018 | 29350730 |
| the impact of preapheresis white blood cell count on autologous peripheral blood stem cell collection efficiency and hsc infusion side effect rate. | autologous peripheral blood hematopoietic stem cell (pbsc) collection efficiency (ce) is reportedly affected by the patient's blood properties; however, studies to identify factors correlated with ce have shown inconsistent results. additionally, variables such as stem cell graft granulocyte content and patient age, sex, and underlying disease, may be associated with hematopietic stem cell (hsc) infusion-related adverse reactions. in this study, we evaluated the correlation of preleukapheresis p ... | 2018 | 29350425 |
| gastrointestinal protists and helminths of habituated agile mangabeys (cercocebus agilis) at bai hokou, central african republic. | infectious diseases including those caused by parasites can be a major threat to the conservation of endangered species. there is thus a great need for studies describing parasite infections of these species in the wild. here we present data on parasite diversity in an agile mangabey (cercocebus agilis) group in bai hokou, dzanga-sangha protected areas (dspa), central african republic. we coproscopically analyzed 140 mangabey fecal samples by concentration techniques (flotation and sedimentation ... | 2018 | 29350404 |
| ems-induced mutation followed by quizalofop-screening increased lipid productivity in chlorella sp. | the objective of this study was to enhance biomass and lipid productivity in chlorella sp. isolate 6-4 by inducing mutagenesis with two growth inhibitors: the herbicide quizalofop-p-ethyl, a known inhibitor of acetyl-coa carboxylase (accase) activity, and chemical mutagen, ethyl methanesulfonate (ems), at different concentrations and length of times. the induced-mutagenized microalgae were screened on selective medium containing 10-100 µm quizalofop. the biomass yield, biomass productivity, lipi ... | 2018 | 29350295 |
| diversity and enzymatic potentialities of bacillus sp. strains isolated from a polluted freshwater ecosystem in cuba. | genotypic and phenotypic characterization of bacillus spp. from polluted freshwater has been poorly addressed. the objective of this research was to determine the diversity and enzymatic potentialities of bacillus spp. strains isolated from the almendares river. bacilli strains from a polluted river were characterized by considering the production of extracellular enzymes using api zym. 14 strains were selected and identified using 16s rrna, gyrb and aroe genes. genotypic diversity of the bacill ... | 2018 | 29350293 |
| chitinophaga caseinilytica sp. nov., a casein hydrolysing bacterium isolated from forest soil. | a novel casein hydrolysing bacterium designated strain s-52t was isolated from kyonggi university forest soil. cells were strictly aerobic, gram stain-negative, oxidase- and catalase- positive, non-motile, non-spore-forming, rod-shaped, and golden-yellow-pigmented. strain s-52t hydrolysed casein. it was able to grow at 20-37 °c (optimum 25-32 °c), ph 6.5-11.0 (optimum 7-9.5), and at 3% (w/v) nacl concentration. strain exhibits flexirubin-type pigments. phylogenetic analysis based on 16s rrna gen ... | 2018 | 29350245 |
| correction to: mental health needs and psychoactive drug use in a user population of the family health strategy (fhs) in ribeirão preto, são paulo, brazil. | the original version of this article unfortunately published without acknowledgement. the funding information and grant number is given below: funding research supported by research in public for the national health care system (pp-sus), grant number 12/51732-9. | 2018 | 29349728 |
| a two-stage system coupling hydrolytic acidification with algal microcosms for treatment of wastewater from the manufacture of acrylonitrile butadiene styrene (abs) resin. | to demonstrate the effectiveness of a novel two-stage system coupling hydrolytic acidification with algal microcosms for the treatment of acrylonitrile butadiene styrene (abs) resin-manufacturing wastewater. | 2018 | 29349626 |
| xyla and xylb overexpression as a successful strategy for improving xylose utilization and poly-3-hydroxybutyrate production in burkholderia sacchari. | despite the versatility and many advantages of polyhydroxyalkanoates as petroleum-based plastic substitutes, their higher production cost compared to petroleum-based polymers has historically limited their large-scale production. one appealing approach to reducing production costs is to employ less expensive, renewable feedstocks. xylose, for example is an abundant and inexpensive carbon source derived from hemicellulosic residues abundant in agro-industrial waste (sugarcane bagasse hemicellulos ... | 2018 | 29349569 |
| description of alteromonas abrolhosensis sp. nov., isolated from sea water of abrolhos bank, brazil. | two gram-negative, motile, aerobic bacteria isolated from waters of the abrolhos bank were classified through a whole genome-based taxonomy. strains pel67et and pel68c shared 99% 16s rrna and dnak sequence identity with alteromonas marina sw-47t and alteromonas macleodii atcc 27126t. in silico dna-dna hybridization, i.e. genome-to-genome distance (ggd), average amino acid identity (aai) and average nucleotide identity (ani) showed that pel67et and pel68c had identity values between 33-36, 86-88 ... | 2018 | 29349565 |
| hendra virus spillover is a bimodal system driven by climatic factors. | understanding environmental factors driving spatiotemporal patterns of disease can improve risk mitigation strategies. hendra virus (hev), discovered in australia in 1994, spills over from bats (pteropus sp.) to horses and thence to humans. below latitude - 22°, almost all spillover events to horses occur during winter, and above this latitude spillover is aseasonal. we generated a statistical model of environmental drivers of hev spillover per month. the model reproduced the spatiotemporal patt ... | 2018 | 29349533 |
| oral bacterial colonization on dental implants restored with titanium or zirconia abutments: 6-month follow-up. | this investigation aimed to characterize in a 6-month follow-up the microbial profile of implants restored with either titanium or zirconia abutments at the genus or higher taxonomic levels. | 2018 | 29349504 |
| auto-aggregation properties of a novel aerobic denitrifier enterobacter sp. strain fl. | enterobacter sp. strain fl was newly isolated from activated sludge and exhibited significant capability of auto-aggregation as well as aerobic denitrification. the removal efficiencies of no3--n, total nitrogen (tn), and toc by strain fl in batch culture reached 94.6, 63.9, and 72.5% in 24 h, respectively. the production of n2o and n2 in the presence of oxygen demonstrated the occurrence of aerobic denitrification. the auto-aggregation index of strain fl reached 54.3%, suggesting a high tendenc ... | 2018 | 29349490 |
| characterization of multiple antilisterial peptides produced by sakacin p-producing lactobacillus sakei subsp. sakei 2a. | antimicrobial compounds produced by lactic acid bacteria can be explored as natural food biopreservatives. in a previous report, the main antimicrobial compounds produced by the brazilian meat isolate lactobacillus sakei subsp. sakei 2a, i.e., bacteriocin sakacin p and two ribosomal peptides (p2 and p3) active against listeria monocytogenes, were described. in this study, we report the spectrum of activity, molecular mass, structural identity and mechanism of action of additional six antilisteri ... | 2018 | 29349489 |
| continuous splitting of aqueous droplets at the interface of co-flowing immiscible oil streams in a microchannel. | we report the continuous splitting of aqueous droplets at the interface between two co-flowing immiscible oil streams in a microchannel. the aqueous droplets initially present in a primary continuous stream (cp1) migrate into a secondary continuous stream (cp2) when the ratio of the non-inertial lift force to the interfacial tension force exceeds a critical value (k. s. jayaprakash, u. banerjee and a. k. sen, langmuir, 2016, 32, 2136-2143). here, experiments were performed to understand the drop ... | 2018 | 29349475 |
| draft genome sequence of xylaria sp., the causal agent of taproot decline of soybean in the southern united states. | the draft genome of xylaria sp. isolate msu_sb201401, causal agent of taproot decline of soybean in the southern u.s., is presented here. the genome assembly was 56.7 mb in size with an l50 of 246. a total of 10,880 putative protein-encoding genes were predicted, including 647 genes encoding carbohydrate-active enzymes and 1053 genes encoding secreted proteins. this is the first draft genome of a plant-pathogenic xylaria sp. associated with soybean. the draft genome of xylaria sp. isolate msu_sb ... | 2018 | 29349107 |
| combined treatment of contaminated soil with a bacterial stenotrophomonas strain dxz9 and ryegrass (lolium perenne) enhances ddt and dde remediation. | bioremediation of contaminated soils by a combinational approach using specific bacterial species together with ryegrass is a promising strategy, resulting in potentially highly efficient degradation of organic contaminants. the present study tested the combination of strain dxz9 of stenotrophomonas sp. with ryegrass to remove ddt and dde contaminants from soil under natural conditions in a pot experiment. the strain dxz9 was successfully colonized in the natural soil, resulting in removal rates ... | 2018 | 29354855 |
| an access to 1,3-azasiline-fused quinolinones via oxidative heteroannulation involving silyl c(sp3)-h functionalization. | a mn-promoted intermolecular oxidative radical heteroannulation of n-(2-cyanoaryl)-acrylamides and tertiary silanes has been described, which provides an efficient route to produce silicon/nitrogen heterocycles, sila-analogues of the known carbon-based structural motifs prevalent in bioactive natural products, pharmaceuticals and materials. the reaction enables si-incorporation by controlling accurately several chemical bond cleavage and formation processes. moreover, this reaction represents a ... | 2018 | 29354826 |
| calligonum comosum and fusarium sp. extracts as bio-mediator in silver nanoparticles formation: characterization, antioxidant and antibacterial capability. | in the current study, extracellular biosynthesis of silver nanoparticles (agnps) was carried out using aqueous extracts of green calligonum comosum stem, besides fusarium sp. synthesized agnps were characterized using ultraviolet (uv)-vis spectrophotometer, transmission electron microscopy (tem) and zeta potential. moreover, biosynthesized agnps were estimated for the scavenging ability on dpph radical as well as tested for their antibacterial activity using well diffusion method against gram-po ... | 2018 | 29354383 |
| isolation, characterization and exploring biotechnological potential of halophilic archaea from salterns of western india. | thirteen halophilic archaea were isolated from kandla and bhayander salt pans. these isolates were grouped into three different genera halobacterium, haloferax and haloarcula based on morphological and biochemical characterization, polar lipid analysis, amplified 16s rdna restriction analysis (ardra) and 16s rdna sequence analysis. biochemical characterization suggested the ability of isolates to produce protease, amylase and poly-hydroxybutyrate (phb) indicating their biotechnological potential ... | 2018 | 29354356 |
| gerstmann's syndrome and unilateral optic ataxia in the emergency department. | a 75-year-old right-handed woman presented to the emergency department with simultanagnosia and right unilateral optic ataxia. moreover, the patient had agraphia, acalculia, digital agnosia and right-left disorientation, consistent with complete gerstmann's syndrome. this case highlights the concurrence of gerstmann's syndrome and unilateral optic ataxia in the acute phase of a left middle cerebral artery stroke. | 2018 | 29354229 |
| cardiovascular risk factors and cognitive performance in aging. | atherosclerosis in cerebral blood vessels, especially those which compose the circle of willis, can lead to reduced supply of oxygen and nutrients to different cortical structures, affecting cognitive function. | 2018 | 29354226 |
| increased csf levels of total tau in patients with subcortical cerebrovascular pathology and cognitive impairment. | cognitive impairment includes mild cognitive decline and dementia, such as alzheimer's disease (ad) and cerebrovascular-related pathologies. | 2018 | 29354223 |
| association between diabetes and causes of dementia: evidence from a clinicopathological study. | diabetes mellitus is a risk factor for dementia, especially for vascular dementia (vad), but there is no consensus on diabetes as a risk factor for alzheimer's disease (ad) and other causes of dementia. | 2018 | 29354221 |
| hypertension, diabetes and obesity are associated with lower cognitive performance in community-dwelling elderly: data from the fibra study. | systemic hypertension (sh), diabetes mellitus (dm) and abdominal obesity may negatively impact cognitive performance. | 2018 | 29354220 |
| impact of hypertension severity on arterial stiffness, cerebral vasoreactivity, and cognitive performance. | aging, hypertension (htn), and other cardiovascular risk factors contribute to structural and functional changes of the arterial wall. | 2018 | 29354219 |
| neuroimaging in cerebral small vessel disease: update and new concepts. | in recent years, small vessel disease (svd) has been recognized for its major impact on cognitive impairment in elderly people, where it is often difficult to separate its effects from those of neurodegenerative diseases individually. svd is a systemic disease, probably related to diffuse endothelial dysfunction, which affects the perforating arterioles, capillaries and venules in the brain. although often asymptomatic, it is responsible for almost half of all dementia cases and a significant pr ... | 2018 | 29354213 |
| plasmodium dihydrofolate reductase is a second enzyme target for the antimalarial action of triclosan. | malaria, caused by parasites of the genus plasmodium, leads to over half a million deaths per year, 90% of which are caused by plasmodium falciparum. p. vivax usually causes milder forms of malaria; however, p. vivax can remain dormant in the livers of infected patients for weeks or years before re-emerging in a new bout of the disease. the only drugs available that target all stages of the parasite can lead to severe side effects in patients with glucose-6-phosphate dehydrogenase (g6pd) deficie ... | 2018 | 29348637 |
| stingless bee larvae require fungal steroid to pupate. | the larval stage of the stingless bee scaptotrigona depilis must consume a specific brood cell fungus in order to continue development. here we show that this fungus is a member of the genus zygosaccharomyces and provides essential steroid precursors to the developing bee. insect pupation requires ecdysteroid hormones, and as insects cannot synthesize sterols de novo, they must obtain steroids in their diet. larval in vitro culturing assays demonstrated that consuming ergosterol recapitulates th ... | 2018 | 29348592 |
| two new lankacidin-related metabolites from streptomyces sp. hs-nf-1178. | two new lankacidin-related metabolites, 2,18-seco-lankacidinol a (1), 2,18-seco-lankacidinol b (2) and a known compound, lankacidinol (3), were isolated from the fermentation broth of streptomyces sp. hs-nf-1178. their structures were determined on the basis of spectroscopic analysis, including 1d and 2d nmr techniques as well as esi-ms and comparison with data from the literature. these two new compounds, especially compound 1, exhibited potent antitumor activity. | 2018 | 29348529 |
| cordybislactone, a stereoisomer of the 14-membered bislactone clonostachydiol, from the hopper pathogenic fungus cordyceps sp. bcc 49294: revision of the absolute configuration of clonostachydiol. | cordybislactone (3), a new stereoisomer of the 14-membered bislactone clonostachydiol, together with its open ring analog (4), was isolated from the hopper pathogenic fungus cordyceps sp. bcc 49294. the relative and absolute configurations of 3 were determined by chemical derivatizations, including the modified mosher's method. the stereochemistry of clonostachydiol was determined using the natural compound isolated from xylaria sp. bcc 4297. the result revealed that the absolute configuration o ... | 2018 | 29348525 |
| linearmycins are lytic membrane-targeting antibiotics. | the linearmycin family of polyketides was originally classified as antifungal metabolites. however, in addition to antifungal activity, we previously found that linearmycins cause cellular lysis and colony degradation of the gram-positive bacterium bacillus subtilis. we recently showed that streptomyces sp. strain mg1 incorporates linearmycins into extracellular vesicles, which are capable of lysing b. subtilis. however, the mechanism of linearmycin-induced lysis was hitherto unexplored. therefo ... | 2018 | 29348524 |
| jbir-150, a novel 20-membered polyene macrolactam from marine-derived streptomyces sp. opma00071. | during the course of constructing a natural product library for drug screening consisting of microbial culture extracts originated from marine samples, we evaluated natural product components profiles via uplc tof-ms and routine biological tests for cytotoxic and antibiotic activities for all of the culture extract samples. by combination of chemical screening and biological activities, we succeeded in discovering a 20-membered macrolactam antibiotic subsequently designated jbir-150 (1) from a m ... | 2018 | 29348521 |
| prime-boost vaccination with recombinant protein and adenovirus-vector expressing plasmodium vivax circumsporozoite protein (csp) partially protects mice against pb/pv sporozoite challenge. | vaccine development against plasmodium vivax malaria lags behind that for plasmodium falciparum. to narrow this gap, we administered recombinant antigens based on p. vivax circumsporozoite protein (csp) to mice. we expressed in pichia pastoris two chimeric proteins by merging the three central repeat regions of different csp alleles (vk210, vk247, and p. vivax-like). the first construct (ypvcsp-allfl) contained the fused repeat regions flanked by n- and c-terminal regions. the second construct ( ... | 2018 | 29348479 |
| speciation of common gram-negative pathogens using a highly multiplexed high resolution melt curve assay. | the identification of the bacterial species responsible for an infection remains an important step for the selection of antimicrobial therapy. gram-negative bacteria are an important source of hospital and community acquired infections and frequently antimicrobial resistant. speciation of bacteria is typically carried out by biochemical profiling of organisms isolated from clinical specimens, which is time consuming and delays the initiation of tailored treatment. whilst molecular methods such a ... | 2018 | 29348433 |
| complete genome sequence of kyrpidia sp. strain ea-1, a thermophilic knallgas bacterium, isolated from the azores. | kyrpidia sp. strain ea-1 is a thermophilic hydrogen-oxidizing bacterium isolated from hydrothermal systems at são miguel island, portugal. here, we present the complete genome sequence of the strain assembled to a single circular chromosome. the genome spans 3,352,175 bp, with a gc content of 58.7%. | 2018 | 29348358 |
| draft genome sequences of 14 strains of pseudomonas isolated from prunus sp. plants. | we present here the draft genome sequences of 14 pseudomonas strains isolated from prunus sp. plants in new zealand and overseas. these new genomic data will be used to improve the detection of pseudomonas strains found in imported plant material at the new zealand border, improving the time involved in the process of biosecurity decision-making. | 2018 | 29348350 |
| draft genome sequence of the crude oil-degrading and biosurfactant-producing strain cobetia sp. qf-1. | we report here the draft genome of cobetia sp. qf-1, a cold-adapted bacterium isolated from crude oil-contaminated seawater of the yellow sea, china. this genome is approximately 4.1 mb (g+c content, 57.44%) with 3,513 protein-coding sequences. cobetia sp. qf-1 shows crude oil degradation and biosurfactant production activity at low temperature. | 2018 | 29348342 |
| draft genome sequences of strains tre 1, tre d, tre h, and tri 7, isolated from tamarins and belonging to four putative novel bifidobacterium species. | bifidobacterium sp. strains tre 1, tre d, tre h, and tri 7 were isolated from two tamarins housed in parco natura viva, garda zoological park s.r.l. (bussolengo, verona, italy). these strains belong to four putative novel species of the genus bifidobacterium the genome sizes were 2.7 mb for tre 1, 2.7 mb for tre d, 2.4 mb for tre h, and 2.7 mb for tri 7. the average gc contents were 63.18% for tre 1, 58.27% for tre d, 57.11% for tre h, and 63.79% for tri 7. | 2018 | 29348339 |
| draft genome sequence of a novel bacterium, pseudomonas sp. strain mr 02, capable of pyomelanin production, isolated from the mahananda river at siliguri, west bengal, india. | the draft genome sequence of a novel strain, pseudomonas sp. mr 02, a pyomelanin-producing bacterium isolated from the mahananda river at siliguri, west bengal, india, is reported here. this strain has a genome size of 5.94 mb, with an overall g+c content of 62.6%. the draft genome reports 5,799 genes (mean gene length, 923 bp), among which 5,503 are protein-coding genes, including the genes required for the catabolism of tyrosine or phenylalanine for the characteristic production of homogentisi ... | 2018 | 29348338 |
| complete genome sequence of sphingorhabdus sp. ygsmi21, exhibiting high enantioselective epoxide hydrolase activity. | sphingorhabdus sp. ygsmi21 is a novel strain exhibiting high enantioselective hydrolysis activity for styrene oxide. here, we present its complete genome sequence, consisting of one circular chromosome (3.86 mb) and one plasmid (0.196 mb). | 2018 | 29348337 |
| draft genome sequences of phenotypically distinct janthinobacterium sp. isolates cultured from the hudson valley watershed. | investigation of the hudson valley watershed reveals many violacein-producing bacteria. these are of interest for their biotherapeutic potential in treating chytrid infections of amphibians. the draft whole-genome sequences for seven janthinobacterium isolates with a variety of phenotypes are provided in this study. | 2018 | 29348334 |
| domestic feline contribution in the transmission of sporothrix in rio de janeiro state, brazil: a comparison between infected and non-infected populations. | sporotrichosis is a neglected zoonosis caused by pathogenic fungi belonging to the sporothrix schenckii complex. in rio de janeiro state, this disease reached an epidemic status with over 4700 domestic felines and around 4000 humans affected since the mid-90s. the present study evaluated clinical and epidemiological aspects and also the frequency of colonization and infection by these fungi in healthy cats and among those with suspicious cutaneous lesions, inhabiting four rio de janeiro state di ... | 2018 | 29347940 |
| synthesis of quinazolines via an iron-catalyzed oxidative amination of n-h ketimines. | an efficient synthesis of quinazolines based on an iron-catalyzed c(sp3)-h oxidation and intramolecular c-n bond formation using tert-buooh as the terminal oxidant is described. the reaction of readily available 2-alkylamino benzonitriles with various organometallic reagents led to 2-alkylamino n-h ketimine species. the fecl2-catalyzed c(sp3)-h oxidation of the alkyl group employing tert-buooh followed by intramolecular c-n bond formation and aromatization afforded a wide variety of 2,4-disubsti ... | 2018 | 29341614 |
| current knowledge of nocardiosis in teleost fish. | nocardia sp. is the causative agent of nocardiosis, a lethal granulomatous disease of the skin, muscle, and various inner tissues affecting various teleost and shellfish. four species of nocardia have been isolated from diseased fish and shellfish, namely nocardia asteroides, nocardia seriolae, nocardia salmonicida and nocardia crassostreae. therefore, in fish aquaculture, nocardiosis has caused severe economic losses, especially in the asian region. considerable research has been performed, sin ... | 2018 | 29341219 |
| impact of trans-fats on heat-shock protein expression and the gut microbiota profile of mice. | partially hydrogenated oils are known to cause metabolic stress and dyslipidemia. this paper explores a new dimension about the interaction between dietary trans-fats and the defense heat-shock protein (hsp) system, inflammation, and the gut microbiota of mice consuming a hyperlipidic diet containing partially hydrogenated vegetable oil free of animal fat. five diet groups were installed: control diet, 2 hyperlipidic-partially hydrogenated-oil diets, each containing either casein or whey-protein ... | 2018 | 29341193 |
| identification and characterization of a new three-component nicotinic acid hydroxylase nahab1 b2 from pusillimonas sp. strain t2. | nicotinic acid (na) is ubiquitous in nature and its microbial degradation mechanisms are diverse. in this study, pusillimonas sp. strain t2 was found to be capable of utilizing na as sole carbon and nitrogen sources. this strain could completely degrade 300 mg l-1 na within 3.5 h at 30 °c and ph 7.0. and one of the degradation intermediate of na was identified as 6-hydroxynicotinic acid (6hna). the draft genome sequences of strain t2 was determined to have a total length of 3.3 m bp and 3,054 pr ... | 2018 | 29341170 |
| clinicopathological, genomic and immunological factors in colorectal cancer prognosis. | numerous factors affect the prognosis of colorectal cancer (crc), many of which have long been identified, such as patient demographics and the multidisciplinary team. in more recent years, molecular and immunological biomarkers have been shown to have a significant influence on patient outcomes. whilst some of these biomarkers still require ongoing validation, if proven to be worthwhile they may change our understanding and future management of crc. the aim of this review was to identify the ke ... | 2018 | 29341159 |
| dual effects of creatinine on the formation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (phip). | creatinine was found to not only act as a precursor of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (phip) formation but also inhibit phip formation in a creatinine/phenylalanine model system. the dual mechanistic effects of creatinine on phip formation were then investigated in a model system. adducts of creatinine-phip were detected by quadrupole-time-of-flight mass spectrometry and were found to be a likely explanation for the substantial decrease in the yield of phip when excess creatini ... | 2018 | 29341141 |
| internal medicine residents' attitudes toward simulated depressed cardiac patients during an objective structured clinical examination: a randomized study. | physician biases toward mental conditions such as depression have been shown to adversely affect medical outcomes. | 2018 | 29340941 |
| a new flesh fly species (diptera: sarcophagidae) parasitic on leptodactylid frogs. | here we describe a new species of sarcophagid fly reared from larvae found feeding on three species of leptodactylid frogs collected in subtropical corrientes province in northeastern argentina. our species description is based on adult male and female external morphology and genitalia. adult males and females of the new species were associated with certainty because all specimens studied were reared from single clutches of larvae on each of three infested frogs. thus, adult males and females re ... | 2018 | 29340784 |
| strigeid parasites of circus buffoni from argentina, with the description of a new species of parastrigea szidat, 1928. | studying the helminthological collection of museo de la plata (mlp-he), several specimens of digeneans, recovered parasitizing a long-winged harrier, circus buffoni (accipitridae) from buenos aires argentina, were analysed. the morphological and morphometric analysis of these specimens revealed the presence of two strigeid species, one of them new for science. parastrigea buffoni n. sp. is characterised by a forebody differentiated in a retractile cephalic region with a large opening and a ballo ... | 2018 | 29340782 |
| membrane position dependency of the pka and conductivity of the protein ion channel. | the dependency of current-voltage characteristics of the α-hemolysin channel on the channel position within the membrane was studied using poisson-nernst-planck theory of ion conductivity with soft repulsion between mobile ions and protein atoms (sp-pnp). the presence of the membrane environment also influences the protonation state of the residues at the boundary of the water-lipid interface. in this work, we predict that asp and lys residues at the protein rim change their protonation state up ... | 2018 | 29340712 |
| microbial degradation of triclosan by a novel strain of dyella sp. | a novel strain capable of degrading triclosan was isolated from the acclimated activated sludge and identified to be dyella sp. ww1 based on 16s rdna analysis. the effect of initial concentration of triclosan (0.2, 1, 5, and 10 mg/l), temperature (15, 25, and 35 °c), ph (5, 7, and 9), and additional carbon source on the degradation of triclosan was investigated in a mineral medium. the results showed that dyella sp. ww1 can use triclosan as sole carbon source and degrade it when initial triclosa ... | 2018 | 29340711 |
| fundoplication conversion in roux-en-y gastric bypass for control of obesity and gastroesophageal reflux: systematic review. | obesity is related with higher incidence of gastroesophageal reflux disease. antireflux surgery has inadequate results when associated with obesity, due to migration and/or subsequent disruption of antireflux wrap. gastric bypass, meanwhile, provides good control of gastroesophageal reflux. | 2018 | 29340554 |
| mini-gastric bypass: description of the technique and preliminary results. | in recent years, a surgical technique known as single-anastomosis gastric bypass or mini-gastric bypass has been developed. its frequency of performance has increased considerably in the current decade. | 2018 | 29340551 |
| the relation among the physical activity level during leisure time, anthropometry, body composition, and physical fitness of women underwent of bariatric surgery and an equivalent group with no surgery. | bariatric surgery is an alternative to the obesity treatment. | 2018 | 29340548 |
| interesfincterial ligation of fistula tract (lift) for patients with anal fistulas: a brazilian bi-institutional experience. | the best treatment for anal fistula should extirpate infection and promote healing of the tract, whilst preserving the anal sphincter complex and full continence. | 2018 | 29340544 |
| colostomy closure: risk factors for complications. | : the restoration of intestinal continuity is an elective procedure that is not free of complications; on the contrary, many studies have proven a high level of morbidity and mortality. it is multifactorial, and has factors inherent to the patients and to the surgical technique. | 2018 | 29340543 |
| bedside ultrasound is a practical measurement tool for assessing muscle mass. | to evaluate the intra- and inter-reliability and the ease of measuring the quadriceps muscle thickness using bedside ultrasound. | 2018 | 29340537 |
| prevalence of cytomegalovirus disease in kidney transplant patients in an intensive care unit. | to define the frequency of cytomegalovirus disease among kidney transplant patients in an intensive care unit in which this complication was suspected and to identify predisposing factors and their possible impact on clinical outcome. | 2018 | 29340535 |
| more than two decades after the introduction of limnoperna fortunei (dunker 1857) in la plata basin. | the golden mussel, limnoperna fortunei, is an asian freshwater bivalve introduced in south america in the beginning of the 1990's, probably through ballast water releases in la plata river estuary. it dispersed north through paraná, uruguay and paraguay rivers. the study evaluated the macroscale (18° to 34° s; 45° to 60° w) distribution of l. fortunei (larval stages) in the main rivers and reservoirs of la plata basin. samplings were performed through 68 µm vertical plankton net hauls. limnologi ... | 2018 | 29340533 |
| the use of biosimilar medicines in oncology - position statement of the brazilian society of clinical oncology (sboc). | a biosimilar is a biologic product that is similar to a reference biopharmaceutical product, the manufacturing process of which hinders the ability to identically replicate the structure of the original product, and therefore, it cannot be described as an absolute equivalent of the original medication. the currently available technology does not allow for an accurate copy of complex molecules, but it does allow the replication of similar molecules with the same activity. as biosimilars are about ... | 2018 | 29340530 |
| time collection and storage conditions of lipid profile. | the stability of samples is crucial for getting reliable concentrations of many analytes, including lipid profile. thus, the goal of this study was to analyze lipid profile under different storage and temperature conditions. this was a prospective study with 809 patients of both genders. total cholesterol, triglycerides, high-density lipoprotein cholesterol, low density lipoprotein cholesterol and non-high-density lipoprotein were measured within 1 h from collection at room temperature, after 2- ... | 2018 | 29340525 |
| efficacy of removal of cariogenic bacteria and carious dentin by ablation using different modes of er:yag lasers. | the primary objective of this in vitro study was to evaluate the efficiency of removal of cariogenic bacteria and carious dentin by ablation using two lasers: fluorescence-feedback controlled (ffc) er:yag laser and different pulses of er:yag laser based on variable square pulse technology (vspt). the secondary objective was to measure the temperature during laser ablation of carious tissue. seventy-two extracted human molars were used in this study. sixty teeth with carious dentin were randomly ... | 2018 | 29340524 |
| strategies to optimize medline and embase search strategies for anesthesiology systematic reviews. an experimental study. | a high-quality electronic search is essential for ensuring accuracy and comprehensiveness among the records retrieved when conducting systematic reviews. therefore, we aimed to identify the most efficient method for searching in both medline (through pubmed) and embase, covering search terms with variant spellings, direct and indirect orders, and associations with mesh and emtree terms (or lack thereof). | 2018 | 29340504 |
| epidemiological situation of acquired immunodeficiency syndrome (aids)-related mortality in a municipality in northeastern brazil. a retrospective cross-sectional study. | the number of acquired immunodeficiency syndrome (aids)-related deaths covers different segments of the population differently, making monitoring of this mortality essential. the aim of this study was to describe the epidemiological situation of aids-related mortality in a municipality in the northeastern region of brazil. | 2018 | 29340503 |
| accidents involving motorcycles and potential years of life lost. an ecological and exploratory study. | traffic accidents have gained prominence as one of the modern epidemics that plague the world. the objective of this study was to identify the spatial distribution of potential years of life lost (pyll) due to accidents involving motorcycles in the state of são paulo, brazil. | 2018 | 29340501 |
| respiratory evaluation through volumetric capnography among grade iii obese and eutrophic individuals: a comparative study. | excess trunk body fat in obese individuals influences respiratory physiological function. the aims of this study were to compare volumetric capnography findings (vcap) between severely obese patients and normal-weight subjects and to assess whether there is any association between neck circumference (nc), waist-hip ratio (whr) and vcap among grade iii obese individuals. | 2018 | 29340500 |
| omalizumab in patients with severe uncontrolled asthma: well-defined eligibility criteria to promote asthma control. | 2018 | 29340498 | |
| mortality from idiopathic pulmonary fibrosis: a temporal trend analysis in brazil, 1979-2014. | to analyze mortality from idiopathic pulmonary fibrosis (ipf) in brazil over the period 1979-2014. | 2018 | 29340493 |
| survival in a cohort of patients with lung cancer: the role of age and gender in prognosis. | to determine the demographic and clinical characteristics of patients with non-small cell lung cancer (nsclc), as well as their disease course, by age group and gender. | 2018 | 29340491 |
| understanding diagnostic tests. part 2. | 2018 | 29340487 | |
| evolution in the management of non-small cell lung cancer in brazil. | 2018 | 29340484 | |
| idiopathic pulmonary fibrosis in brazil: challenges for epidemiological characterization and management. | 2018 | 29340483 | |
| clear cell odontogenic carcinoma of the mandible: a treatment strategy. | clear cell odontogenic carcinoma (ccoc) is a rare odontogenic tumor of the jaws, histologically characterized by the presence of agglomerates of cells with eosinophilic cytoplasm. the patient, a 62-year-old caucasian woman, presented an intraosseous lesion in the mandibular symphysis. a clinical examination revealed a discrete volumetric increase with a hard consistency, palpable to extraoral and intraoral examinations. imaging studies revealed an extensive radiolucent area, without defined limi ... | 2018 | 29340482 |
| bone repair access of boneceramic™ in 5-mm defects: study on rat calvaria. | the aim of this study was to evaluate the osteoconductive potential of boneceramic™ on bone healing in rat calvaria 5-mm defects. | 2018 | 29340480 |
| enzymes immobilized in langmuir-blodgett films: why determining the surface properties in langmuir monolayer is important? | in this review we discuss about the immobilization of enzymes in langmuir-blodgett films in order to determine the catalytic properties of these biomacromolecules when adsorbed on solid supports. usually, the conformation of enzymes depends on the environmental conditions imposed to them, including the chemical composition of the matrix, and the morphology and thickness of the film. in this review, we show an outline of manuscripts that report the immobilization of enzymes as lb films since the ... | 2018 | 29340479 |
| the long and successful journey of electrochemically active amino acids. from fundamental adsorption studies to potential surface engineering tools. | proteins have been the subject of electrochemical studies. it is possible to apply electrochemical techniques to obtain information about their structure due to the presence of five electroactive amino acids that can be oriented to the outside of the peptidic chain. these amino acids are l-tryptophan (l-trp), l-tyrosine (l-tyr), l-histidine (l-his), l-methionine (l-met) and l-cysteine (l-cys); their electrochemical behavior being subject of extensive research, but it is still controversial. no s ... | 2018 | 29340478 |
| prevalence of and risk factors associated with the presence of staphylococcus aureus in the chronic wounds of patients treated in primary health care settings in brazil. | wounds can be colonized by methicillin-resistant staphylococcus aureus (mrsa). | 2018 | 29340463 |
| rhodnius stali: new vector infected by trypanosoma rangeli (kinetoplastida, trypanosomatidae). | rhodnius stali infection by trypanosoma rangeli is reported in this study for the first time. | 2018 | 29340462 |
| synanthropic triatomines as potential vectors of trypanosoma cruzi in central brazil. | chagas disease surveillance requires current knowledge on synanthropic triatomines. we analyzed the occurrence and trypanosoma cruzi infection rates of triatomine bugs in central brazil, during 2012-2014. | 2018 | 29340461 |
| first serologic evidence of human hantavirus infection in alagoas state in northeastern brazil. | hantavirus cardiopulmonary syndrome (hcps) is rare in northeastern brazil. | 2018 | 29340460 |