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the striking geographical pattern of gastric cancer mortality in spain: environmental hypotheses revisited.gastric cancer is decreasing in most countries. while socioeconomic development is the main factor to which this decline has been attributed, enormous differences among countries and within regions are still observed, with the main contributing factors remaining elusive. this study describes the geographic distribution of gastric cancer mortality at a municipal level in spain, from 1994-2003.200919737377
determinants of organochlorine levels detectable in the amniotic fluid of women from tenerife island (canary islands, spain).organochlorines (ocs) tend to accumulate in human tissues and can be measured in amniotic fluid (af). the detection of ocs in af samples reflects intrauterine exposure of human beings to these persistent organic pollutants. the present study was performed to evaluate the level of contamination of af by ocs in 100 pregnant women from tenerife island (canary islands, spain). gas chromatography/mass spectrometry (gc/ms) was used to identify and quantify the analytes, including 7 polychlorobiphenyl ...200919403124
consort hypersensitivity pneumonitis.to date, there is little information in the literature that hypersensitivity pneumonitis due to birds may occur without direct contact to birds. a 62-yr-old pensioner developed mild flu-like symptoms, fatigue and polyuria several hours after each meeting with his new female partner, either in hotels or his apartment. after divorcing from her ex-husband, who was a canary fancier, the female had moved into a bungalow approximately 6 months earlier. when the couple met for the first time at the bun ...200919407057
prenatal environmental effects match offspring begging to parental provisioning.the solicitation behaviours performed by dependent young are under selection from the environment created by their parents, as well as wider ecological conditions. here we show how mechanisms acting before hatching enable canary offspring to adapt their begging behaviour to a variable post-hatching world. cross-fostering experiments revealed that canary nestling begging intensity is positively correlated with the provisioning level of their own parents (to foster chicks). when we experimentally ...200919419982
radiometric analysis of farmed fish (sea bass, gilthead bream, and rainbow trout) from tenerife island, spain.this study analyzed the content of gamma-emitting radionuclides in fish farmed on the island of tenerife (canary islands, spain). the fish species included in this study were sea bass, gilthead bream, and rainbow trout. the first two species are produced in offshore enclosures, while the third is produced in a freshwater fish farm. all measurements were performed using two high-purity germanium gamma-ray detectors. the content of gamma-emitting radionuclides in the fodder used to feed the differ ...200919777898
daily dietary intake of iron, copper, zinc and manganese in a spanish population.to evaluate the daily dietary intake of essential metals in the canary islands, the iron, copper, zinc and manganese contents in 420 food and drink samples collected in local markets were analysed by inductively coupled plasma-atomic emission spectrometry (icp-aes). the estimated daily dietary intakes of iron, copper, zinc and manganese are 13.161 mg/day, 2.098 mg/day, 8.954 mg/day and 2.372 mg/day, respectively. the iron dietary intake was found to be below the recommendations fixed for adult w ...200919817638
temporal evolution of the abo allele frequencies in the canary islands: the impact of the european colonization.the indigenous canary islands population suffered a strong cultural and genetic impact when they were colonized by europeans in the fifteenth century. the molecular analysis of the abo blood group gene on aboriginal and seventeenth to eighteenth century remains confirms the demographic history of the islands depicted by previous archaeological, anthropological, and genetic studies. abo allele frequencies clearly related canarian aborigines with north african berber populations, its most probable ...200919693495
"canary measures" among the ahrq patient safety indicators.despite the fact that the agency for healthcare research and quality patient safety indicators (psis) are useful for evaluating adverse events in hospitals, the 20 psis make it difficult to summarize broad trends across indicators. this study aims to identify 1 or more measures among the psis best suited for a quick index of general patient safety status. the 1997-2002 nationwide inpatient sample was used to calculate the hospital-level risk-adjusted rates of the psis. both pairwise correlation ...200919696232
atoxoplasmosis in canary fledglings: severe lymphocytic enteritis with preferential parasitism of b lymphocytes.all fledgling canaries (serinum canarius) in a small private aviary died from atoxoplasmosis during a single breeding season. the birds were clinically normal when removed from their parents at 2 mo of age, but by 3 mo of age all had died following an illness characterized by progressive lethargy, anorexia, and debilitation. cachexia, splenomegaly, and pale foci in the liver were evident at necropsy. microscopically, there was striking infiltration of the intestinal lamina propria by mononuclear ...200919848092
high prevalence of asthma and allergic diseases in children aged 6 and 7 years from the canary islands: the international study of asthma and allergies in childhood.to investigate the prevalence of bronchial asthma and allergic diseases in schoolchildren from the canary islands, spain.200919862938
unusual pathology of canary poxvirus infection associated with high mortality in young and adult breeder canaries (serinus canaria).mortality in excess of 65% occurred in a flock of 450 canaries (serinus canaria). clinical signs in the canaries included severe respiratory distress, loss of feathers and/or scaly skin on the head, neck and back, anorexia, loss of weight and fluffed-up appearance of several days duration before death. gross pathology in most of the canaries included thickened eye lids and small scab-like nodules on the skin of the head and neck, enlarged thymus, mild to severe consolidation of lungs and exudate ...200919937516
study of an unusual paratyphoid epornitic in canaries (serinus canaria).high mortalities in 17 canary flocks from different regions of tehran, iran, were reported. necropsy and histopathologic examination revealed necrotic hepatitis and overall congestive septicaemia in carcasses. salmonella enterica was isolated from 34 examined samples, two samples from each flock, including visceral organs of carcasses and droppings of live diseased birds. all isolates were typed as salmonella enterica serovar typhimurium by conventional serotyping. antibiotic resistance profilin ...200919937532
gene polymorphisms in tyms, mthfr, p53 and mdr1 as risk factors for breast cancer: a case-control study.breast cancer (bc) is a complex disease influenced by environmental and genetic factors. the disease has important genetic and environmental components, most of them are still unknown. an important role of gene polymorphisms related to the risk of developing bc has been reported. however, the results have been controversial. we investigated the association of tser, mthfr c677t, p53 codon 72 and mdr1 c3435t gene polymorphisms with breast carcinoma in women from canary islands (spain). blood sampl ...200919885596
[lifestyle and treatment adherence of type 2 diabetes mellitus people in the canary islands].the canary islands population experiences the highest type 2 diabetes (dm2) mortality in spain. we studied lifestyle, unknown dm2 and treatment adherence in diabetics of these islands.200919893884
the relationship among mental health status (ghq-12), health related quality of life (eq-5d) and health-state utilities in a general population.to assess the relationship between mental health and health-related quality of life (hrql) in the general population, and to map ghq-12 as a screening test for population psychological distress to a generic health state measure (eq-5d) in order to estimate health state values and allow deriving quality-adjusted life years.200920034201
trachea epithelium as a "canary" for cigarette smoking-induced biologic phenotype of the small airway epithelium.the initial site of smoking-induced lung disease is the small airway epithelium, which is difficult and time consuming to sample by fiberoptic bronchoscopy. we developed a rapid, office-based procedure to obtain trachea epithelium without conscious sedation from healthy nonsmokers (n= 26) and healthy smokers (n= 19, 27 +/- 15 pack-year). gene expression differences (fold change >1.5, p < 0.01, benjamini-hochberg correction) were assessed with affymetrix microarrays. a total of 1,057 probe sets w ...200920443905
microsatellite loci isolation in the canarian common chaffinch (fringilla coelebs) and their utility in other canarian finches.the taxonomic classification of the common chaffinch (fringilla coelebs) that inhabits the canary islands has been under debate for decades, mainly due to the absence of nuclear dna analyses. in this study we describe the isolation and characterization of ten microsatellite loci (aaag, aaat and gt) from a la palma specimen using an enrichment protocol. two loci were monomorphic in the populations analysed (la gomera and la palma), but the remaining ones presented 2 or more alleles, with an avera ...200921564863
species of botryosphaeriaceae occurring on proteaceae.the botryosphaeriaceae includes several species that are serious canker and leaf pathogens of proteaceae. in the present study, sequence data for the its nrdna region were used in conjunction with morphological observations to resolve the taxonomy of species of botryosphaeriaceae associated with proteaceae. neofusicoccum luteum was confirmed from buckinghamia and banksia in australia, and on protea cynaroides in south africa. a major pathogen of banksia coccinea in australia was shown to be n. a ...200820396581
co-speech gesture in bimodal bilinguals.the effects of knowledge of sign language on co-speech gesture were investigated by comparing the spontaneous gestures of bimodal bilinguals (native users of american sign language and english; n = 13) and non-signing native english speakers (n = 12). each participant viewed and re-told the canary row cartoon to a non-signer whom they did not know. nine of the thirteen bimodal bilinguals produced at least one asl sign, which we hypothesise resulted from a failure to inhibit asl. compared with no ...200819430579
isolation and characterization of 21 microsatellite markers in the barn owl (tyto alba).we report 21 new polymorphic microsatellite markers in the european barn owl (tyto alba). the polymorphism of the reported markers was evaluated in a population situated in western switzerland and in another from tenerife, canary islands. the number of alleles per locus varies between two and 31, and expected heterozygosity per population ranges from 0.16 to 0.95. all loci are in hardy-weinberg equilibrium and no linkage disequilibrium was detected. two loci exhibit a null allele in the tenerife ...200821585946
opportunistic nectar-feeding birds are effective pollinators of bird-flowers from canary islands: experimental evidence from isoplexis canariensis (scrophulariaceae).insular floras, characterized by simple pollination networks, sometimes include novel mutualistic agents such as nonspecialist nectarivores. in this study we confirmed the effective pollination of isoplexis canariensis by opportunistic nectar-feeding birds in tenerife, canary islands, spain. this plant is among the ornithophilous species of the canarian flora that lack past and present specialist nectarivorous birds. experimental hand pollinations revealed self-compatibility, but cross-pollinate ...200821628148
hybridization, polyploidy, and evolutionary transitions between monoecy and dioecy in bryonia (cucurbitaceae).correns's 1903 (berichte der deutschen botanischen gesellschaft 21: 133-147) crosses between a monoecious and a dioecious species of bryonia revealed the simple mendelian inheritance of dioecy and provided the first instance of an xy sex determination system in any organism. bryonia ranges from the canary islands to central asia and comprises seven dioecious and three monoecious species; its closest relative, ecballium elaterium, has dioecious and monoecious populations. we used chloroplast (cp) ...200821632334
dna from herbarium specimens settles a controversy about origins of the european potato.landrace potato cultivars are native to two areas in south america: the high andes from eastern venezuela to northern argentina and the lowlands of south-central chile. potato first appeared outside of south america in europe in 1567 and rapidly diffused worldwide. two competing hypotheses suggested the origin of the "european" potato from the andes or from lowland chile, but the andean origin has been widely accepted over the last 60 years. all modern potato cultivars predominantly have chilean ...200821632349
canary in a coal mine? interest in bupropion sr use among smokers in the compass trial. 200819023832
[characterization of the atmospheric environment in las palmas de gran canaria and santa cruz de tenerife, spain: 2000-2004].the island factor in the cities of las palmas de gran canaria and santa cruz de tenerife, their meteorology and the proximity to the african continent that originates the natural particulate matter transport over the islands, cause some specific features in their air quality. the aim of this paper is to characterize the air pollution from 2000 to 2004 as exposure indicator of both cities inhabitants.200819039503
[validation of a food intake frequency questionnaire adapted for the study and monitoring of the adult population of the canary islands, spain].the registering of eating habits requires a valid and reliable method. the purpose of this study is to validate the food intake frequency questionnaire, cdc-ffq, which is an adaptation of another questionnaire, in order to assess the nutrition of the adult population of the canary islands.200819039504
[presentation of the "cdc de canarias" cohort: objectives, design and preliminary results].the canary islands rank first in spain with respect to the ischaemic heart disease and diabetes mortality rates. the islands female population leads the country in deaths from breast cancer. the "cdc de canarias" is a general population cohort study in order to analyse the prevalence and incidence of these diseases and the exposure to their risk factors (rf) in the adult population of the archipelago.200819039505
[mortality related with alcohol in spain and the different autonomous communities of spain in 2004].alcohol consumption is associated with great morbidity-mortality rate. the aim of this study is to analyze the mortality that can be attributed to alcohol consumption in spain and in its different autonomous communities during 2004.200819000474
molecular characterization of a poxvirus isolated from an american flamingo (phoeniconais ruber rubber).an avian poxvirus from the beak scab of an american flamingo (phoeniconais ruber rubber) was isolated by inoculation on the chorioallantoic membrane (cam) of specific-pathogen-free (spf) chicken embryos. the virus produced multifocal areas of epithelial hyperplasia along with foci of inflammation in the cam, and rare cells contained small eosinophilic intracytoplasmic bodies. chickens inoculated with the isolated virus in the feather follicle of the leg did not develop significant lesions. nucle ...200818939646
the potential pathogenicity of chlorhexidine-sensitive acanthamoeba strains isolated from contact lens cases from asymptomatic individuals in tenerife, canary islands, spain.pathogenic strains of the genus acanthamoeba are causative agents of a serious sight-threatening infection of the eye known as acanthamoeba keratitis. the prevalence of this infection has risen in the past 20 years, mainly due to the increase in number of contact lens wearers. in this study, the prevalence of acanthamoeba in a risk group constituted by asymptomatic contact lens wearers from tenerife, canary islands, spain, was evaluated. contact lenses and contact lens cases were analysed for th ...200818927419
[hemoglobin stanleyville ii [alpha78(ef7)asn --> lys]. first case described in spain].structural hemoglobinopathies are the result of mutations in the genes of globin, which determine a qualitative alteration in the expression of these genes. most alterations do not originate any significant change, and correspond to silent or asymptomatic forms. this study proves a new case of hemoglobin (hb) stanleyville ii.200818928738
much to know about proteolysis: intricate proteolytic machineries compromise essential cellular functions.proteolysis has traditionally been considered as a radical way to terminate the function of a protein. however, protein destruction also is the starting point for many processes as they can only occur when the way has been cleared for the action of other proteins. protein destruction can occur virtually in all compartments and organelles of the cell, associated with cell membranes or large protein complexes, it determines subcellular partitioning, association with positive or negative regulators ...200818793136
genetic structuring and migration patterns of atlantic bigeye tuna, thunnus obesus (lowe, 1839).large pelagic fishes are generally thought to have little population genetic structuring based on their cosmopolitan distribution, large population sizes and high dispersal capacities. however, gene flow can be influenced by ecological (e.g. homing behaviour) and physical (e.g. present-day ocean currents, past changes in sea temperature and levels) factors. in this regard, atlantic bigeye tuna shows an interesting genetic structuring pattern with two highly divergent mitochondrial clades (clades ...200818798987
noradrenergic deficits alter processing of communication signals in female songbirds.during acoustic communication, animals must attend to sounds from a particular source while simultaneously rejecting intrusion from other sources. one possible candidate mechanism for this process is the noradrenergic system. noradrenaline is a neuromodulator that tunes sensory processing systems and regulates attention. we examined whether pharmacological degradation of the noradrenergic system using n-(2-chloroethyl)-n-2-bromobenzyl-amine hydrochloride (dsp-4) modifies processing of species-ty ...200818815444
herpes simplex-like infection in a bottlenose dolphin stranded in the canary islands.a bottlenose dolphin, stranded in the canary islands in 2001 exhibited non-suppurative encephalitis. no molecular detection of cetacean morbillivirus (cemv) was found, but a herpesviral-specific band of 250 bp was detected in the lung and brain. the sequenced herpesviral pcr product was compared with genbank sequences, obtaining 98% homology (p-distance of 0.02) with human herpesvirus 1 (herpes simplex virus 1 or hsv-1). this is the first report of a herpes simplex-like infection in a stranded d ...200818828564
gloeodontia xerophila (aphyllophorales, basidiomycota), a new species with corticioid basidioma from the canary islands.gloeodontia xerophila sp. nov. is described and illustrated from material collected on dead xerophyte debris in the canary islands. this species is characterized by the odontioid hymenophore with short aculei, up to 2 mm long, dimitic hyphal system and amyloid, subglobose and verrucose spores, 4-5 x 3-4 microm. the new taxon is compared with other species in the genus and a key to the species of gloeodontia is provided.200818833760
organochlorine pesticide levels in loggerhead turtles (caretta caretta) stranded in the canary islands, spain. 200818834602
[physicians' attitudes and perceptions regarding the critical care and critical care specialty].to evaluate the attitudes and perceptions of the doctors of a hospital regarding critical care and the speciality of intensive medicine.200818842223
multiple colonizations, in situ speciation, and volcanism-associated stepping-stone dispersals shaped the phylogeography of the macaronesian red fescues (festuca l., gramineae).whereas examples of insular speciation within the endemic-rich macaronesian hotspot flora have been documented, the phylogeography of recently evolved plants in the region has received little attention. the macaronesian red fescues constitute a narrow and recent radiation of four closely related diploid species distributed in the canary islands (f. agustinii), madeira (f. jubata), and the azores (f. francoi and f. petraea), with a single extant relative distributed in mainland southwest europe ( ...200818853360
splenic marginal zone lymphoma--a clinicopathological study in a series of 16 patients.splenic marginal zone lymphoma (smzl), characterized in the who classification of lymphoid tumors, is a rare disorder comprising less than 1% of lymphoid neoplasms; only a few series concerning this entity have been published. although this type of lymphoma is well defined histologically, its histogenesis remains obscure. moreover, specific biological markers are still lacking and immunophenotype profile is not specific. these and other reasons, such as the existence of cytogenetic subtypes, hav ...200818854089
municipal distribution of ovarian cancer mortality in spain.spain was the country that registered the greatest increases in ovarian cancer mortality in europe. this study describes the municipal distribution of ovarian cancer mortality in spain using spatial models for small-area analysis.200818789142
inverse association between serum resistin and insulin resistance in humans.to determine how serum concentrations of resistin are distributed in humans in relation to insulin resistance, type 2 diabetes, and obesity.200818789551
hplc-ms analysis and anti-oedematogenic activity of hypericum grandifolium choisy (hypericaceae).a study has been carried out on the chemical composition and in vivo anti-oedematogenic activity of several extracts from hypericum grandifolium choisy (hypericaceae) collected in tenerife (canary islands). the hplc-ms analysis (hplc-esi/ms and hplc-ft/ms) revealed the presence of hyperforin, flavonoids and probably benzophenone derivatives, while naphthodianthrones were absent. pharmacological results revealed that the methanol extracts and the aqueous, butanol and chloroform fractions obtained ...200818484525
response properties of the auditory telencephalon in songbirds change with recent experience and season.the caudomedial nidopallium (ncm) is a telencephalic auditory area that is selectively activated by conspecific vocalizations in zebra finches and canaries. we recently demonstrated that temporal and spectral dynamics of auditory tuning in ncm differ between these species [1]. in order to determine whether these differences reflect recent experience, we exposed separate groups of each species and sex to different housing conditions. adult birds were housed either in an aviary with conspecifics ( ...200818682724
use of a synthetic gnrh analog to induce reproductive activity in canaries (serinus canaria).in this study, we evaluated the effects of a transcutaneously administered gonadotropin-releasing hormone analog (lecirelin) on the reproductive activity of the canary (serinus canaria). two groups of 20 pairs of canaries were treated with increasing concentrations of lecirelin delivered in a cream vehicle; one group was exposed to a natural photoperiod, and the other group received additional photostimulation. two groups of 10 pairs of canaries served as controls; one group was exposed to an ar ...200818689073
cytokine il-1 beta but not il-1 alpha promoter polymorphism is associated with alzheimer disease in a population from the canary islands, spain.previous studies have reported the presence of low-grade inflammation in alzheimer disease (ad). based on these data, our work attempts to investigate the effects of some promoter polymorphisms of pro-inflammatory cytokines [interleukin (il)-1 alpha and il-1 beta] on ad.200818717723
main pigmentary features and melanocortin 1 receptor (mc1r) gene polymorphisms in the population of the canary islands.sun exposure, light skin pigmentation, and melanocortin 1 receptor (mc1r) gene variants are independent risk factors for skin cancer. the canary islands have a sunny and temperate climate, but data regarding the phenotypic and genotypic risk factors among the population are lacking.200818717860
evolution of caries and fluorosis in schoolchildren of the canary islands (spain): 1991, 1998, 2006.the aim of this work is to assess the evolution of caries and fluorosis prevalence and indices at 7 and 12 years of age in the canary islands through three cross epidemiological studies conducted in 1991, 1998 and 2006. the three studies followed a similar methodology, using the who diagnosis criteria and indications, except for the assessment of fluorosis, which was measured with the "thylstrup and fejerskov" index. the examining dentists were trained and calibrated in an area with high endemic ...200818758407
genetic characterization, distribution and prevalence of avian pox and avian malaria in the berthelot's pipit (anthus berthelotii) in macaronesia.exotic pathogens have been implicated in the decline and extinction of various native-island-bird species. despite the fact that there is increasing concern about the introduction of diseases in island ecosystems, little is known about parasites in the islands of macaronesia. we focus on berthelot's pipit (anthus berthelotii), an endemic and widespread macaronesian bird species, using a combination of field studies and molecular techniques to determine: (1) the range and prevalence of avian pox ...200818762985
wdr1 presence in the songbird basilar papilla.wd40 repeat 1 protein (wdr1) was first reported in the acoustically injured chicken inner ear, and bioinformatics revealed that wdr1 has numerous wd40 repeats, important for protein-protein interactions. it has significant homology to actin interacting protein 1 (aip1) in several lower species such as yeast, roundworm, fruitfly and frog. several studies have shown that aip1 binds cofilin/actin depolymerizing factor, and that these interactions are pivotal for actin disassembly via actin filament ...200818514449
frequent, phylogenetically local horizontal transfer of the cox1 group i intron in flowering plant mitochondria.horizontal gene transfer is surprisingly common among plant mitochondrial genomes. the first well-established case involves a homing group i intron in the mitochondrial cox1 gene shown to have been frequently acquired via horizontal transfer in angiosperms. here, we report extensive additional sampling of angiosperms, including 85 newly sequenced introns from 30 families. analysis of all available data leads us to conclude that, among the 640 angiosperms (from 212 families) whose cox1 intron sta ...200818524785
hyponastic leaf growth decreases the photoprotective demand, prevents damage to photosystem ii and delays leaf senescence in salvia broussonetii plants.the influence of leaf angle on the response of plants to high light was studied in salvia broussonetii, a species endemic of the canary islands that shows hyponastic leaf growth. the response of vertical, naturally oriented leaves was compared with that of horizontal, artificially held leaves for 1, 13, 24 and 29 days in terms of photoinhibition [efficiency of photosystem ii (psii)], photoprotection (by the xanthophyll cycle, alpha-tocopherol and beta-carotene) and progression of leaf senescence ...200818533002
serum resistin and polymorphisms of androgen receptor gagn and ggnn and aromatase tttan.there is evidence that androgens are regulators of insulin resistance (ir), and may be involved in the regulation of resistin, a cytokine that has been related with ir. earlier studies found that androgen receptor length polymorphisms cagn and ggnn and the aromatase polymorphism tttan may influence receptor or enzyme activity and serum concentrations of androgens. this study was designed to determine whether polymorphism length was related to serum resistin concentration and to other variables r ...200818535544
first outbreak of trypanosoma evansi in camels in metropolitan france.the first outbreak of trypanosomosis caused by trypanosoma evansi in camels in france was reported on a farm in the aveyron department. five camels were imported from the canary islands to the farm in early july 2006, and trypanosomes were observed on a stained blood smear from one of them, which died in october. on further investigations, trypanosomes were observed in the blood of five camels, three of them indigenous to the farm and two that had been imported. on the basis of microscopical exa ...200818540034
phylogeny of the celastreae (celastraceae) and the relationships of catha edulis (qat) inferred from morphological characters and nuclear and plastid genes.the phylogeny of celastraceae tribe celastreae, which includes about 350 species of trees and shrubs in 15 genera, was inferred in a simultaneous analysis of morphological characters together with nuclear (its and 26s rdna) and plastid (matk, trnl-f) genes. a strong correlation was found between the geography of the species sampled and their inferred relationships. species of maytenus and gymnosporia from different regions were resolved as polyphyletic groups. maytenus was resolved in three line ...200818550389
quantification of polyphenols with potential antioxidant properties in wines using reverse phase hplc.a rp-hplc method with photodiode array detection (dad) was developed to separate, identify and quantify simultaneously the most representative phenolic compounds present in madeira and canary islands wines. the optimized chromatographic method was carefully validated in terms of linearity, precision, accuracy and sensitivity. a high repeatability and a good stability of phenolics retention times (< 3%) were obtained, as well as relative peak area. also high recoveries were achieved, over 80.3%. ...200818563759
systemic listeriosis in caged canaries (serinus canarius).the occurrence of listeriosis in 12 caged canaries is described where 50% of the birds, including the female and all of the offspring, died within 2 weeks without clinical signs. at necropsy, multifocal necrotizing and partly granulomatous hepatitis, splenitis, myocarditis, interstitial nephritis, and exudative pericarditis with intra-lesional listeria monocytogenes were the predominant findings as shown by histopathology and immunohistochemistry. microbiology, serology and polymerase chain reac ...200818568661
[hospital management of pancreatic cancer in spain and assessment of factors associated with in-hospital mortality].pancreatic cancer is becoming an increasingly important health problem in spain. this study aimed to analyze the hospital management of this process and the factors associated with mortality by using an administrative data base.200818570807
seasonality in song behaviour revisited: seasonal and annual variants and invariants in the song of the domesticated canary (serinus canaria).the song of the domesticated canary (serinus canaria) is one of the most widely used models to study the neural correlates of behavioural plasticity and the mechanisms of female mate choice. however, only few studies have described the song behaviour in detail and monitored their changes throughout the year, and these data are restricted to the "waterslager" strain. here, we studied the song characteristics of the male common domesticated canary at different times of the year, the spring breedin ...200818571653
[the development of primary care related to regional governmental policies].to developed an evaluation of primary care (pc) from the analysis of the new differences in pc among the autonomous communities nowadays.200818588797
photoperiodic induced changes in reproductive state of border canaries (serinus canaria) are associated with marked variation in hypothalamic gonadotropin-releasing hormone immunoreactivity and the volume of song control regions.in temperate zone songbirds, such as canaries (serinus canaria), seasonal variation in gonadal activity and behavior are associated with marked brain changes. these include gonadotropin-releasing hormone (gnrh) expression and the volume of brain areas controlling song production. questions have been raised about the consistency of seasonal brain changes in canaries. laboratory studies of the american singer strain raised doubts as to whether this strain exhibits a robust photoperiodic response a ...200818597755
diuretic activity of smilax canariensis, an endemic canary island species.smilax canariensis is an endemic species of the canary islands, popularly known as "zarzaparrilla sin espinas". this species has wide use in folk-medicine practice on the islands, especially as diuretic. so the aim of our study is to evaluate the diuretic activity of an aqueous and a methanol extract of this species.200818602777
suitability of pines and other conifers as hosts for the invasive mediterranean pine engraver (coleoptera: scolytidae) in north america.the invasive mediterranean pine engraver, orthotomicus erosus (wollaston) (coleoptera: scolytidae), was detected in north america in 2004, and it is currently distributed in the southern central valley of california. it originates from the mediterranean region, the middle east, and asia, and it reproduces on pines (pinus spp.). to identify potentially vulnerable native and adventive hosts in north america, no-choice host range tests were conducted in the laboratory on 22 conifer species. the bee ...200818613584
killing the canary: the international epidemiology of the homicide of media workers.to describe the international epidemiology of the homicide of media workers, and investigate country-level risk factors.200818621952
avian olfactory receptor gene repertoires: evidence for a well-developed sense of smell in birds?among vertebrates, the sense of smell is mediated by olfactory receptors (ors) expressed in sensory neurons within the olfactory epithelium. comparative genomic studies suggest that the olfactory acuity of mammalian species correlates positively with both the total number and the proportion of functional or genes encoded in their genomes. in contrast to mammals, avian olfaction is poorly understood, with birds widely regarded as relying primarily on visual and auditory inputs. here, we show that ...200818628122
total dietary intake of mercury in the canary islands, spain.estimating the risk associated with dietary intake of heavy metals by consumers is a vital and integral part of regulatory processes. the assessment of exposure to mercury shown in this paper has been performed by means of a study on the whole diet. total mercury (hg) levels were determined by cold vapour atomic absorption spectrometry (aas) in 420 samples of regularly consumed food and drink. the total hg concentrations measured in the different groups of food ranged from non-detectable to 119 ...200818629690
intestinal barrier dysfunction, endotoxemia, and gastrointestinal symptoms: the 'canary in the coal mine' during exercise-heat stress?reduced intestinal blood flow and high intestinal temperatures during exercise-heat stress can lead to intestinal barrier dysfunction. such dysfunction may increase intestinal permeability to endotoxin. during exercise-heat stress, intestinal barrier dysfunction and endotoxemia can produce gastrointestinal symptoms and increased production of pro-inflammatory cytokines. such problems may be a warning sign ('canary in the coal mine') for the onset of exertional heat stroke. failure to heed such a ...200819208999
natural infection with cryptosporidium galli in canaries (serinus canaria), in a cockatiel (nymphicus hollandicus), and in lesser seed-finches (oryzoborus angolensis) from brazil.proventricular infection by cryptosporidium sp. or cryptosporidium galli has been associated with mortality, weight loss, diarrhea, and pasty feces. the purpose of this study is to report the occurrence of natural c galli infection in canaries (serinus canaria), in a cockatiel (nymphicus hollandicus), and in lesser seed-finches (oryzoborus angolensis) with clinical complaints of apathy and sporadic mortality. screening for cryptosporidium spp. using microscopic examination of fecal samples and s ...200819166068
fitness to drive of psychiatric patients.driving a motor vehicle could be central to the functional autonomy of patients with psychiatric illnesses. for patients, a driver's license could mean independence, the ability to care for themselves, and the freedom to travel when they wish. however, both psychiatric disorders and psychiatric drug treatments can produce changes in perception, information processing and integration, and psychomotor activity that can disturb and/or interfere with the ability to drive safely.200819158977
use of cymelarsan in goats chronically infected with trypanosoma evansi.toxicity and therapeutic trials using cymelarsan (an arsenical compound) against trypanosoma evansi infection were carried out using chronically infected goats. for the toxicity trial, 40 goats were divided into four groups of 10 animals each; the first three groups received s.c. injections of 5, 10, and 15 mg/kg bw of cymelarsan, respectively, and the last one served as control. no systemic reaction was observed in any goat throughout the experiment. for the therapeutic trial, 15 adult female g ...200819120242
comparing therapeutic efficacy between ivermectin, selamectin, and moxidectin in canaries during natural infection with dermanyssus gallinae.the aim of this study was to compare the efficacy of three spot-on drugs on canaries during dermanyssus gallinae natural infections and during the breeding season. three groups of canary couples (seven couples each) were included: group a was treated with ivermectin, b with selamectin, and c with moxidectin. all the drugs were administered topically infrascapularly. the parasitic charge was estimated before the treatment (t(0)) and after 8 (t(1)), 16 (t(2)), 24 (t(3)), and 32 (t(4)) days followi ...200819120251
ossifying fibroma in a canary (serinus canaria).a 1-year-old male canary (serinus canaria, jibber breed), with a protuberance on the left tibia was referred to the clinic. the bird was not able to use the affected foot to stand on its perch. results of radiographs revealed a radio-opaque hard tissue mass. the canary was euthanatized and submitted for necropsy. on histopathologic examination, the mass was diagnosed as an ossifying fibroma tumor. to our knowledge, ossifying fibroma has not been reported in birds so far, and this is the first kn ...200819216260
spatio-temporal upwelling trends along the canary upwelling system (1967-2006).spatio-temporal trends in upwelling patterns were studied along the canary upwelling system for the period 1967-2006. the northwestern coast of african from lat 20 degrees n to 32 degrees n is observed to be under a permanent upwelling regime characterized by coastal sea surface temperatures (sst) colder than the oceanic ones at the same latitude. the temperature difference is termed the temperature upwelling index (ui(sst)). this regime is consistent with the wind-derived ekman transport (ui(w) ...200819076422
helicobacter pylori and caga seroprevalence in sub-saharan inmigrants recently arrived to gran canaria (spain).non-ulcerous dyspepsia is common among sub-saharan people migrating into spain. given the high prevalence of h. pylori (hp) infection in their countries of origin, we studied the prevalence of infection in this population, and specifically the prevalence of infection by the more virulent, caga-positive strains (cap). 140 sub-saharan immigrants recently arrived to gran canaria (canary islands, spain) were studied. 80.7% were male, with a mean age of 24.2 y. 90.7% tested seropositive for hp and 72 ...200819086248
influence of harvest time on fuel characteristics of five potential energy crops in northern china.five potential energy crops in northern china were examined for fuel characteristics over different harvest times to test whether or not a delayed harvest improves fuel quality in a semiarid area in china as is the case in northern europe and north america. the five crops include indigo bush (amorpha fruticosa), sand willow (salix cheilophila), switch grass (panicum virgatum), reed canary grass (phalaris arundinacea), and sainfoin (onobrychis viciifolia). these crops are considered as fuels for ...200817382539
mycobacterium marinum infection complicating crohn's disease, treated with infliximab.tumour necrosis factor-alpha inhibitors including infliximab are often used to treat a number of recalcitrant medical conditions. these agents are increasingly associated with infections, particularly mycobacterial infections. we report sporotrichoid spread of mycobacterium marinum in a 37-year-old woman with crohn's disease, who had been receiving infliximab infusions for 2 years. an infection had spread up the right leg, after she had been swimming on holiday in the canary islands. m. marinum ...200817983451
sensitization to tomato peel and pulp extracts in the mediterranean coast of spain: prevalence and co-sensitization with aeroallergens.tomatoes (lycopersicon esculentum) are consumed world-wide. the prevalence of sensitization to tomatoes remains unknown.200818005185
epidemiology of hip fracture in the elderly in spain.to describe the incidence and epidemiological characteristics of hip fracture (hf) in patients aged 65 years or over in the various autonomous regions (ar) of spain from the year 2000 to 2002 and to determine which factors affect in-hospital mortality.200818037366
monitoring concentrations of persistent organic pollutants in the general population: the international experience.assessing the adverse effects on human health of persistent organic pollutants (pops) and the impact of policies aiming to reduce human exposure to pops warrants monitoring body concentrations of pops in representative samples of subjects. while numerous ad hoc studies are being conducted to understand pops effects, only a few countries are conducting nationwide surveillance programs of human concentrations of pops, and even less countries do so in representative samples of the general populatio ...200818054079
the caulerpa racemosa invasion: a critical review.caulerpa racemosa var. cylindracea is a marine chlorophyta introduced into the mediterranean sea from south-western australia. since 1990, it has been invading the mediterranean sea and the canary islands, raising ecological problems. although this invasion event can be considered as one of the most serious in the history of species introduced into the mediterranean sea, c. racemosa has not triggered as much attention as the famous "killer alga"caulerpa taxifolia. the aim of the present study wa ...200818061625
microbial communities and immigration in volcanic environments of canary islands (spain).volcanic eruptions originated the canary islands (spain), and today, different landscapes clearly show that active volcanism. the microbial communities present in these volcanic environments, both at high (above 70 degrees c) and moderate (25-35 degrees c) temperatures, were analyzed. rock samples were processed using molecular techniques based on both dna and rna and complemented with the culture of microorganisms at a wide range of temperatures. microorganisms detected through rna-based molecu ...200818071667
a simple clinical score for type 2 diabetes mellitus screening in the canary islands.to develop a straightforward risk score for type 2 diabetes (dm2) screening to use in clinical practice.200818082285
testosterone-induced matrix metalloproteinase activation is a checkpoint for neuronal addition to the adult songbird brain.testosterone-induced neuronal addition to the adult songbird vocal control center, hvc, requires the androgenic induction of vascular endothelial growth factor (vegf), followed by vegf-stimulated angiogenesis. the expanded vasculature acts as a source of bdnf, which supports the immigration of new neurons from the overlying ventricular zone. in tumorigenesis, a similar process of adult angiogenesis is regulated by matrix metalloproteinase (mmp) activity, in particular that of the gelatinases. we ...200818171938
recent volcanism and mitochondrial dna structuring in the lizard gallotia atlantica from the island of lanzarote.the phylogeography of the lacertid lizard gallotia atlantica from the small volcanic island of lanzarote (canary islands) was analysed based on 1075 bp of mitochondrial dna (mtdna) sequence (partial cytochrome b and nd2) for 157 individuals from 27 sites (including three sites from neighbouring islets). levels of sequence divergence were generally low, with the most distant haplotypes separated by only 14 mutational steps. mtdna divergence appears to coincide with formation of the middle pleisto ...200818179441
usefulness of manufactured tomato extracts in the diagnosis of tomato sensitization: comparison with the prick-prick method.abstract:200818184431
validation of the geographic position of eper-spain industries.the european pollutant emission register in spain (eper-spain) is a public inventory of pollutant industries created by decision of the european union. the location of these industries is geocoded and the first published data correspond to 2001. publication of these data will allow for quantification of the effect of proximity to one or more such plant on cancer and all-cause mortality observed in nearby towns. however, as errors have been detected in the geocoding of many of the pollutant foci ...200818190678
postmenopausal canarian women receiving oral glucocorticoids have an increased prevalence of vertebral fractures and low values of bone mineral density measured by quantitative computer tomography and dual x-ray absorptiometry, without significant changes in parathyroid hormone.daily doses higher than 7.5 mg/daily of prednisone or equivalents confer a great risk of vertebral and hip fractures with a clear dose dependence of fracture risk. information regarding the utility in assessing trabecular bone mineral density by quantitative computer tomography (qct) in these patients, either in the canaries or in spain, is lacking. moreover, in this setting, the importance of secondary hyperparathyroidism is still controversial. design, patients and methods: cross-sectional obs ...200818206602
the ionic liquid 1-hexadecyl-3-methylimidazolium bromide as novel extracting system for polycyclic aromatic hydrocarbons contained in sediments using focused microwave-assisted extraction.a method to extract pahs from sediments is carried out using aqueous solutions containing aggregates of the ionic liquid (il) 1-hexadecyl-3-methylimidazolium bromide (hdmim-br) as the extracting medium. focused microwave-assisted extraction has been used to accelerate the extraction step, followed by hplc with fluorescence detection without clean-up steps to remove the il prior to injection. the method has been applied to certified reference sediment bcr-535 and marine sediments from tenerife (c ...200818206899
organochlorine residues in the blubber and liver of bottlenose dolphins (tursiops truncatus) stranded in the canary islands, north atlantic ocean.polychlorinated biphenyls (pcbs) and chlorinated pesticides: dichlorodiphenyltrichloroethane and its metabolites (ddts), chlordanes (chls), dieldrin, and hexaclorobenzene (hcb) were detected in the blubber and liver of 11 bottlenose dolphins (tursiops truncatus) from the canary islands (north atlantic ocean). samples were obtained from stranded dolphins over the period 1997-2005. among the organochlorines analyzed, pcbs and ddts were predominant in the two tissues, followed in decreasing order b ...200818214918
under the volcano: phylogeography and evolution of the cave-dwelling palmorchestia hypogaea (amphipoda, crustacea) at la palma (canary islands).the amphipod crustacean palmorchestia hypogaea occurs only in la palma (canary islands) and is one of the few terrestrial amphipods in the world that have adapted to a strictly troglobitic life in volcanic cave habitats. a surface-dwelling closely related species (palmorchestia epigaea) lives in the humid laurel forest on the same island. previous studies have suggested that an ancestral littoral orchestia species colonized the humid forests of la palma and that subsequent drought episodes in th ...200818234125
state children's health insurance: the canary in the coal mine? 200818247003
geographical variations in the benefit of applying a prioritization system for cataract surgery in different regions of spain.in spain, there are substantial variations in the utilization of health resources among regions. because the need for surgery differs in patients with appropriate surgical indication, introducing a prioritization system might be beneficial. our objective was to assess geographical variations in the impact of applying a prioritization system in patients on the waiting list for cataract surgery in different regions of spain by using a discrete-event simulation model.200818248668
high quality biofuel pellet production from pre-compacted low density raw materials.in this study, pre-compaction was evaluated as a method to enhance stable reed canary grass pellet production. an experimental design of the factors raw material moisture content, steam addition, raw material bulk density, and die temperature was used to find production conditions for high quality pellets by multiple linear regression modelling of responses. response variables being modelled were variability of pelletizer current (as a measurement of uneven production), pellet bulk density, and ...200818261898
the canary in the coal mine of coronary artery disease. 200818268164
radiation, multiple dispersal and parallelism in the skinks, chalcides and sphenops (squamata: scincidae), with comments on scincus and scincopus and the age of the sahara desert.phylogenetic analysis using up to 1325 base pairs of mitochondrial dna from 179 specimens and 30 species of chalcides, sphenops, eumeces, scincopus and scincus indicates that sphenops arose twice independently within chalcides. it is consequently synonymized with that genus. chalcides in this broader sense originated in morocco, diversifying into four main clades about 10 ma, after which some of its lineages dispersed widely to cover an area 40 times as large. two separate lineages invaded the c ...200818276164
micelle-mediated extractions using nonionic surfactant mixtures and hplc-uv to determine endocrine-disrupting phenols in seawaters.an environmentally friendly method to extract endocrine-disrupting phenols (edps) from seawaters was realized using nonionic surfactant mixtures and micelle-mediated extractions. the preconcentration step was achieved directly in the seawater matrix, and was followed by high-performance liquid chromatography (hplc) with ultraviolet (uv) detection without any clean-up steps to remove the surfactant mixture prior to injection. various nonionic surfactant mixtures were used, and polyoxyethylene-10- ...200818297469
non-controlled biogenic emissions to the atmosphere from lazareto landfill, tenerife, canary islands.[corrected] historically, landfills have been the simplest form of eliminating urban solid waste with the minimum cost. they have been the most usual method for discarding solid waste. however, landfills are considered authentic biochemical reactors that introduce large amounts of contaminants into the environment in the form of gas and leachates. the dynamics of generation and the movement of gas in landfills depend on the input and output parameters, as well as on the structure of the landfill ...200818306888
doublecortin as a marker of adult neuroplasticity in the canary song control nucleus hvc.it is established that in songbirds the size of several brain song control nuclei varies seasonally, based on changes in cell size, dendritic branching and, in nucleus hvc, the incorporation of newborn neurons. in the developing and adult mammalian brain, the protein doublecortin (dcx) is expressed in postmitotic neurons and, as a part of the microtubule machinery, required for neuronal migration. we recently showed that in adult canaries, dcx-immunoreactive (ir) cells are present throughout the ...200818333960
evaluation of the fermentation dynamics of soluble crude protein from three protein sources in continuous culture fermenters.eight dual-flow continuous culture fermenters (1.03 +/- 0.05 l) were used to assess differences in microbial degradation of the soluble cp fraction of canola meal (cmscp), soybean meal (sbmscp), and fish meal (fmscp) using a completely randomized design with two 9-d experimental periods and a solution of tryptone as a control treatment (control). all fermenters received the same basal diet (58% ground corn, 40% canary grass hay, 0.4% vitamin-mineral premix, 1% caco(3), 0.6% salt on a dm basis) i ...200818344304
a three-dimensional mri atlas of the zebra finch brain in stereotaxic coordinates.the neurobiology of birdsong, as a model for human speech, is a fast growing area of research in the neurosciences and involves electrophysiological, histological and more recently magnetic resonance imaging (mri) approaches. many of these studies require the identification and localization of different brain areas (nuclei) involved in the sensory and motor control of song. until now, the only published atlases of songbird brains consisted in drawings based on histological slices of the canary a ...200818358743
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