Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| frequent sugar feeding behavior by aedes aegypti in bamako, mali makes them ideal candidates for control with attractive toxic sugar baits (atsb). | current tools and strategies are not sufficient to reliably address threats and outbreaks of arboviruses including zika, dengue, chikungunya, and yellow fever. hence there is a growing public health challenge to identify the best new control tools to use against the vector aedes aegypti. in this study, we investigated ae. aegypti sugar feeding strategies in bamako, mali, to determine if this species can be controlled effectively using attractive toxic sugar baits (atsb). | 2019 | 31206547 |
| the mosquito immune system and the life of dengue virus: what we know and do not know. | flaviviruses are largely transmitted to humans by their arthropod vectors such as mosquitoes or ticks. the dengue virus (denv) is one of the members of the family flaviviridae and is the causative agent of dengue fever. in the mosquito vector, denv enters through viremic blood meal and replicates in the mid-gut. newly formed virion particles circulate to various mosquito organs and get transmitted to the next host in subsequent bites. aedes aegypti and aedes albopictus have intricate immune cont ... | 2019 | 31200426 |
| entomo-virological surveillance strategy for dengue, zika and chikungunya arboviruses in field-caught aedes mosquitoes in an endemic urban area of the northeast of brazil. | aedes spp. are considered the main vectors of dengue (denv), zika (zikv) and chikungunya (chikv) viruses in the world. arbovirus detection in aedes mosquitoes can alert authorities to possible outbreaks, reducing the impact of these diseases. the purpose of this study was to perform an operational strategy for virological surveillance of denv, zikv and chikv in adult aedes aegypti and aedes albopictus mosquitoes captured at different key-sites in an endemic urban area of the northeast region of ... | 2019 | 31194961 |
| surveys of arboviruses vectors in four cities stretching along a railway transect of burkina faso: risk transmission and insecticide susceptibility status of potential vectors. | background: a severe outbreak of dengue occurred in burkina faso in 2016, with the most cases reported in ouagadougou, that highlights the necessity to implement vector surveillance system. this study aims to estimate the risk of arboviruses transmission and the insecticide susceptibility status of potential vectors in four sites in burkina faso. methods: from june to september 2016, house-to-house cross sectional entomological surveys were performed in four cities stretching along a southwest-t ... | 2019 | 31192232 |
| sustained wolbachia-mediated blocking of dengue virus isolates following serial passage in aedes aegypti cell culture. | wolbachia is an intracellular endosymbiont of insects that inhibits the replication of a range of pathogens in its arthropod hosts. the release of wolbachia into wild populations of mosquitoes is an innovative biocontrol effort to suppress the transmission of arthropod-borne viruses (arboviruses) to humans, most notably dengue virus. the success of the wolbachia-based approach hinges upon the stable persistence of the 'pathogen blocking' effect, whose mechanistic basis is poorly understood. evid ... | 2019 | 31191980 |
| phylogenetic analysis of dengue-2 serotypes circulating in mangroves in northern cordoba, colombia. | in this study, we aimed to identify denv-2 subtypes in aedes aegypti pools collected between 2011 and 2017 in a rural area of northern cordoba, colombia ("la balsa"). | 2019 | 31188919 |
| vector competence of aedes aegypti for different strains of zika virus in argentina. | the importance of zika virus (zikv) has increased noticeably since the outbreak in the americas in 2015, when the illness was associated with congenital disorders. although there is evidence of sexual transmission of the virus, the mosquito aedes aegypti is believed to be the main vector for transmission to humans. this species of mosquito has not only been found naturally infected with zikv, but also has been the subject of study in many vector competence assays that employ different strains of ... | 2019 | 31188869 |
| optimal control of vaccination in a vector-borne reaction-diffusion model applied to zika virus. | zika virus has acquired worldwide concern after a recent outbreak in latin america that started in brazil, with associated neurological conditions such as microcephaly in newborns from infected mothers. the virus is transmitted mainly by aedes aegypti mosquitoes, but direct (sexual) transmission has been documented. we formulate a reaction diffusion model that considers spatial movement of humans and vectors, with local contact transmission of zika virus. vaccination is introduced as a control v ... | 2019 | 31187254 |
| cartography of odor chemicals in the dengue vector mosquito (aedes aegypti l., diptera/culicidae). | this study was aimed to identify the chemical compounds of aedes aegypti that can be potentially used to develop pheromone-based vector control methods. in this study, we compared the chemical compounds collected from the organs of mosquitoes at different developmental stages in the life cycle. we also compared the composition and amount of extracts from the different tissues of male and female adult mosquito. interestingly, we found large amount of c17-c20 ethyl and methyl esters in the wings o ... | 2019 | 31186462 |
| male competition and the evolution of mating and life-history traits in experimental populations of aedes aegypti. | aedes aegypti is an important disease vector and a major target of reproductive control efforts. we manipulated the opportunity for sexual selection in populations of ae. aegypti by controlling the number of males competing for a single female. populations exposed to higher levels of male competition rapidly evolved higher male competitive mating success relative to populations evolved in the absence of competition, with an evolutionary response visible after only five generations. we also detec ... | 2019 | 31185872 |
| assessing the potential interactions between cellular mirna and arboviral genomic rna in the yellow fever mosquito, aedes aegypti. | although the role of exogenous small interfering rna (sirna) and p-element induced wimpy testis (piwi)-interacting rna (pirna) pathways in mosquito antiviral immunity is increasingly better understood, there is still little knowledge regarding the role of mosquito cellular microrna (mirna). identifying direct interactions between the mosquito mirnas and the rna genome of arboviruses and choosing the relevant mirna candidates to explore resulting antiviral mechanisms are critical. here, we carrie ... | 2019 | 31185697 |
| seasonal and geographic variation in insecticide resistance in aedes aegypti in southern ecuador. | insecticide resistance (ir) can undermine efforts to control vectors of public health importance. aedes aegypti is the main vector of resurging diseases in the americas such as yellow fever and dengue, and recently emerging chikungunya and zika fever, which have caused unprecedented epidemics in the region. vector control remains the primary intervention to prevent outbreaks of aedes-transmitted diseases. in many high-risk regions, like southern ecuador, we have limited information on ir. in thi ... | 2019 | 31181073 |
| screening aedes aegypti (diptera: culicidae) populations from pernambuco, brazil for resistance to temephos, diflubenzuron, and cypermethrin and characterization of potential resistance mechanisms. | resistance to chemical insecticides detected in aedes aegypti (l.) mosquitoes has been a problem for the national dengue control program (pncd) over the last years. in order to provide deeper knowledge of resistance to xenobiotics, our study evaluated the susceptibility profile of temephos, diflubenzuron, and cypermethrin insecticides in natural mosquito populations from the pernambuco state, associating these results with the local historical use of such compounds. furthermore, mechanisms that ... | 2019 | 31175834 |
| temperature impacts on dengue emergence in the united states: investigating the role of seasonality and climate change. | tropical mosquito-borne viruses have been expanding into more temperate regions in recent decades. this is partly due to the coupled effects of temperature on mosquito life history traits and viral infection dynamics and warming surface temperatures, resulting in more suitable conditions for vectors and virus transmission. in this study, we use a deterministic ordinary differential equations model to investigate how seasonal and diurnal temperature fluctuations affect the potential for dengue tr ... | 2019 | 31175008 |
| enhanced vector surveillance to control arbovirus epidemics in colombia. | in the wake of the zika epidemic, there has been intensified interest in the surveillance and control of the arbovirus vectors aedes aegypti and aedes albopictus, yet many existing surveillance systems could benefit from improvements. vector control programs are often directed by national governments, but are carried out at the local level, resulting in the discounting of spatial heterogeneities in ecology and epidemiology. furthermore, entomological and epidemiological data are often collected ... | 2019 | 31171922 |
| community assessments for mosquito prevention and control experiences, attitudes, and practices - u.s. virgin islands, 2017 and 2018. | aedes aegypti, the mosquito that carries dengue, chikungunya, and zika viruses, is present throughout the u.s. virgin islands (usvi). to reduce mosquitoborne disease transmission, the usvi department of health (vidoh) is responsible for integrated mosquito management. during january 2016-january 2018, usvi experienced its first zika outbreak, with most cases reported during january-december 2016, as well as two category 5 hurricanes (irma on st. thomas/st. john on september 6, 2017, and maria on ... | 2019 | 31170124 |
| the widespread occurrence and potential biological roles of endogenous viral elements in insect genomes. | modern genomic sequencing and bioinformatics approaches have detected numerous examples of dna sequences derived from dna and rna virus genomes integrated into both vertebrate and insect genomes. retroviruses encode rna-dependent dna polymerases (reverse transcriptases) and integrases that convert their rna viral genomes into dna proviruses and facilitate proviral dna integration into the host genome. surprisingly, dna sequences derived from rna viruses that do not encode these enzymes also occu ... | 2019 | 31167954 |
| rnaseq analysis of aedes albopictus mosquito midguts after chikungunya virus infection. | chikungunya virus (chikv) is an emerging pathogen around the world and causes significant morbidity in patients. a single amino acid mutation in the envelope protein of chikv has led to a shift in vector preference towards aedesalbopictus. while mosquitoes are known to mount an antiviral immune response post-infection, molecular interactions during the course of infection at the tissue level remain largely uncharacterised. we performed whole transcriptome analysis on dissected midguts of aedes a ... | 2019 | 31167461 |
| aedes aegypti microrna, mir-2944b-5p interacts with 3'utr of chikungunya virus and cellular target vps-13 to regulate viral replication. | rna interference is among the most important mechanisms that serve to restrict virus replication within mosquitoes, where micrornas (mirnas) are important in regulating viral replication and cellular functions. these mirnas function by binding to complementary sequences mostly in the untranslated regions of the target. chikungunya virus (chikv) genome consists of two open reading frames flanked by 5' and 3' untranslated regions on the two sides. a recent study from our laboratory has shown that ... | 2019 | 31166953 |
| utilizing larvicidal and pupicidal efficacy of eucalyptus and neem oil against aedes mosquito: an approach for mosquito control. | plant-based products can provide safe and biodegradable mosquito control agents. the essential oils have a strong odor due to complex secondary metabolites and exhibit lower density than that of water, which renders them suitable to form a thin layer above the water surface. the present study was designed to evaluate the larvicidal, pupicidal activity of eucalyptus and neem oils against aedes aegypti and aedes albopictus. | 2019 | 31161087 |
| wolbachia pipientis occurs in aedes aegypti populations in new mexico and florida, usa. | the mosquitoes aedes aegypti (l.) and ae. albopictus skuse are the major vectors of dengue, zika, yellow fever, and chikungunya viruses worldwide. wolbachia, an endosymbiotic bacterium present in many insects, is being utilized in novel vector control strategies to manipulate mosquito life history and vector competence to curb virus transmission. earlier studies have found that wolbachia is commonly detected in ae. albopictus but rarely detected in ae. aegypti. in this study, we used a two-step ... | 2019 | 31161026 |
| molecular evidence of sequential evolution of ddt- and pyrethroid-resistant sodium channel in aedes aegypti. | multiple mutations in the voltage-gated sodium channel have been associated with knockdown resistance (kdr) to ddt and pyrethroid insecticides in a major human disease vector aedes aegypti. one mutation, v1016g, confers sodium channel resistance to pyrethroids, but a different substitution in the same position v1016i alone had no effect. in pyrethroid-resistant ae. aegypti populations, v1016i is often linked to another mutation, f1534c, which confers sodium channel resistance only to type i pyre ... | 2019 | 31158225 |
| blood feeding activates the vitellogenic stage of oogenesis in the mosquito aedes aegypti through inhibition of glycogen synthase kinase 3 by the insulin and tor pathways. | most mosquitoes, including aedes aegypti, only produce eggs after blood feeding on a vertebrate host. oogenesis in a. aegypti consists of a pre-vitellogenic stage before blood feeding and a vitellogenic stage after blood feeding. primary egg chambers remain developmentally arrested during the pre-vitellogenic stage but complete oogenesis to form mature eggs during the vitellogenic stage. in contrast, the signaling factors that maintain primary egg chambers in pre-vitellogenic arrest or that acti ... | 2019 | 31153832 |
| vapor delivery of plant essential oils alters pyrethroid efficacy and detoxification enzyme activity in mosquitoes. | the use of synthetic insecticides to limit the spread of mosquito-borne disease faces a number of significant challenges, including insecticide resistance, concerns related to the environmental impact of widespread insecticide use, as well as slowed development of new insecticide chemistries. one important alternative to broadcast insecticides is the use of personal protection strategies to limit contact with vector species, including the use of spatial repellents that can employ synthetic pyret ... | 2019 | 31153481 |
| transmission of lumpy skin disease virus: a short review. | lumpy skin disease (lsd) is a viral transboundary disease endemic throughout africa and of high economic importance that affects cattle and domestic water buffaloes. since 2012, the disease has spread rapidly and widely throughout the middle eastern and balkan regions, southern caucasus and parts of the russian federation. before vaccination campaigns took their full effect, the disease continued spreading from region to region, mainly showing seasonal patterns despite implementing control and e ... | 2019 | 31152757 |
| barriers that limit the implementation of thermal fogging for the control of dengue in colombia: a study of mixed methods. | thermal fogging of insecticides is a vector control strategy used by the medellin secretary of health to combat dengue. this method is employed during outbreaks to curb populations of potentially infectious adult mosquitoes and interrupt transmission cycles. while this strategy has been used in medellin since 2007, in some years it has not reduced dengue cases as expected. difficulties in the implementation of fumigation strategies, such as lack of opportunity for treatment and public perception ... | 2019 | 31146722 |
| estimating the impact of city-wide aedes aegypti population control: an observational study in iquitos, peru. | during the last 50 years, the geographic range of the mosquito aedes aegypti has increased dramatically, in parallel with a sharp increase in the disease burden from the viruses it transmits, including zika, chikungunya, and dengue. there is a growing consensus that vector control is essential to prevent aedes-borne diseases, even as effective vaccines become available. what remains unclear is how effective vector control is across broad operational scales because the data and the analytical too ... | 2019 | 31145744 |
| effects of constant and fluctuating low temperatures on the development of aedes aegypti (diptera: culicidae) from a temperate region. | most studies of the effects of low temperature on the development of immature stages of aedes aegypti (l.) have been performed at constant temperatures in the laboratory, which may not accurately reflect the variable environmental conditions in the field. thus, the aim of this study was to assess the effect of constant temperatures (ct) and fluctuating low temperatures (ft) on the fitness of ae. aegypti of buenos aires, argentina. three ct treatments (12, 14, and 16°c) and three ft treatments (1 ... | 2019 | 31139823 |
| predatory efficacy of five locally available copepods on aedes larvae under laboratory settings: an approach towards bio-control of dengue in sri lanka. | many countries are in search of more effective and sustainable methods for controlling dengue vectors, due to undeniable inefficiencies in chemical and mechanical vector control methods. bio-control of vectors by copepods is an ideal method of using interactions in the natural ecosystem for vector management, with minimum consequences on the environment. current study determined the predatory efficacy of five locally abundant copepod species on, aedes larvae under laboratory conditions. copepods ... | 2019 | 31136574 |
| chemical composition and larvicidal activity of the essential oil from the leaves of onychopetalum periquino (rusby) d.m. johnson & n.a. murray. | the essential oil (eo) from the leaves of onychopetalum periquino, obtained by hydrodistillation, was analyzed by gas chromatography coupled with mass spectrometry (gc-ms), and also was investigated for its larvicidal activity against aedes aegypti larvae. thirteen compounds, representing 91.31% of the crude oil, were identified. major compounds were sesquiterpenes, including β-elemene (53.16%), spathulenol (11.94%) and β-selinene (9.25%). the eo showed high larvicidal activity with a lethal con ... | 2019 | 31135221 |
| sodium ascorbate as a potential toxicant in attractive sugar baits for control of adult mosquitoes (diptera: culicidae) and sand flies (diptera: psychodidae). | attractive toxic sugar baits (atsbs) can be an effective vector control tool, especially in areas where aerial or aquatic applications of pesticides are undesirable or impractical. in general, there is a need to develop novel or alternative insecticides for vector control, and there is a demand from consumers for more 'natural' pest control products. sodium ascorbate (sa) is a naturally occurring antioxidant compound, found in fruits and vegetables, and is available commercially in the united st ... | 2019 | 31134270 |
| high infestation of invasive aedes mosquitoes in used tires along the local transport network of panama. | the long-distance dispersal of the invasive disease vectors aedes aegypti and aedes albopictus has introduced arthropod-borne viruses into new geographical regions, causing a significant medical and economic burden. the used-tire industry is an effective means of aedes dispersal, yet studies to determine aedes occurrence and the factors influencing their distribution along local transport networks are lacking. to assess infestation along the primary transport network of panama we documented all ... | 2019 | 31133041 |
| the sulcatone receptor of the strict nectar-feeding mosquito toxorhynchites amboinensis. | controlling ae. aegypti populations and the prevention of mosquito bites includes the development of monitoring, repelling and attract-and-kill strategies that are based on understanding the chemical ecology of these pests. olfactory-mediated attraction to mammals has recently been linked to the mosquito aedes aegypti odorant receptor or4, which is activated by animal-released 6-methyl-5-hepten-2-one (sulcatone). this odorant is also a major component of flower scents and may play a role outside ... | 2019 | 31129164 |
| a genomic approach to inferring kinship reveals limited intergenerational dispersal in the yellow fever mosquito. | understanding past dispersal and breeding events can provide insight into ecology and evolution and can help inform strategies for conservation and the control of pest species. however, parent-offspring dispersal can be difficult to investigate in rare species and in small pest species such as mosquitoes. here, we develop a methodology for estimating parent-offspring dispersal from the spatial distribution of close kin, using pairwise kinship estimates derived from genome-wide single nucleotide ... | 2019 | 31125998 |
| linking nutrient stoichiometry to zika virus transmission in a mosquito. | food quality and quantity serve as the basis for cycling of key chemical elements in trophic interactions; yet the role of nutrient stoichiometry in shaping host-pathogen interactions is under appreciated. most of the emergent mosquito-borne viruses affecting human health are transmitted by mosquitoes that inhabit container systems during their immature stages, where allochthonous input of detritus serves as the basal nutrients. quantity and type of detritus (animal and plant) were manipulated i ... | 2019 | 31227906 |
| lichen parmelia sulcata mediated synthesis of gold nanoparticles: an eco-friendly tool against anopheles stephensi and aedes aegypti. | the gold nanoparticles (aunps) were synthesized using the lichen parmelia sulcata extract (pse) and characterized. the peaks of ultraviolet spectrophotometer and fourier transmission infrared confirmed the formation of nanoparticles and the bioactive compounds of the lichen being responsible for reducing and capping of the particles. the face-centered cubic particles were determined by xrd peaks at 111, 200, 220, and 311. the elemental composition and spherical shape of aunps were confirmed by e ... | 2019 | 31218582 |
| how do trait-mediated non-lethal effects of predation affect population-level performance of mosquitoes? | non-lethal, trait-mediated effects of predation impact prey behavior and life-history traits. studying how these effects in turn influence prey demography is crucial to understand prey life-history evolution. mosquitoes are important vectors that claim several million lives every year worldwide by transmitting a range of pathogens. several ecological factors affect life-history traits of both larval and adult mosquitoes, creating effects that cascade to population-level consequences. few studies ... | 2019 | 31218216 |
| community composition and year-round abundance of vector species of mosquitoes make miami-dade county, florida a receptive gateway for arbovirus entry to the united states. | vector-borne diseases are a heavy burden to human-kind. global warming and urbanization have a significant impact on vector-borne disease transmission, resulting in more severe outbreaks, and outbreaks in formerly non-endemic areas. miami-dade county, florida was the most affected area in the continental united states during the 2016 zika virus outbreak. miami is an important gateway and has suitable conditions for mosquitoes year-round. therefore, it was critical to establish and validate a sur ... | 2019 | 31217547 |
| development of cs-tpp-dsrna nanoparticles to enhance rnai efficiency in the yellow fever mosquito, aedes aegypti. | mosquito-borne diseases are a major threat to human health and are responsible for millions of deaths globally each year. vector control is one of the most important approaches used in reducing the incidence of these diseases. however, increasing mosquito resistance to chemical insecticides presents challenges to this approach. therefore, new strategies are necessary to develop the next generation vector control methods. because of the target specificity of dsrna, rnai-based control measures are ... | 2019 | 31217512 |
| mosquitocidal chips containing the insect growth regulator pyriproxyfen for control of aedes aegypti (diptera: culicidae). | aedes aegypti were exposed to water treated with mosquitocidal chips containing the insecticide pyriproxyfen in a polymer formulation. chips were tested under different conditions; different water volumes, in containers made of different material, and in water with different levels of organic matter. treated chips caused 100% mortality of ae. aegypti during their pupal stage independent of size or type of container, and the mount of organic matter contained in the water to which the mosquito lar ... | 2019 | 31216627 |
| oviposition preferences of the mosquito aedes aegypti linnaeus, 1762 (culicidae): an urban environment bioassay. | the establishment of an invasive species depends on reproductive success and dispersion capability in the new environment. one of the striking examples of invasion in urban environments is the mosquito aedes aegypti linnaeus, 1762 (culicidae). the success of this species is primarily attributed to its ability to colonize urban environments, and some of the important adaptive strategies associated with this ability is the preference for humans as a blood source and intense occupation of residenti ... | 2019 | 31213206 |
| inferring who-infected-whom-where in the 2016 zika outbreak in singapore-a spatio-temporal model. | singapore experienced its first known zika outbreak in 2016. given the lack of herd immunity, the suitability of the climate for pathogen transmission, and the year-round presence of the vector- aedes aegypti-zika had the potential to become endemic, like dengue. guillain-barré syndrome and microcephaly are severe complications associated elsewhere with zika and the risk of these complications makes understanding its spread imperative. we investigated the spatio-temporal spread of locally transm ... | 2019 | 31213175 |
| asymptomatic dengue virus infections, cambodia, 2012-2013. | we investigated dengue virus (denv) and asymptomatic denv infections in rural villages of kampong cham province, cambodia, during 2012 and 2013. we conducted perifocal investigations in and around households for 149 denv index cases identified through hospital and village surveillance. we tested participants 0.5-30 years of age by using nonstructural 1 rapid tests and confirmed denv infections using quantitative reverse transcription pcr or nonstructural 1-capture elisa. we used multivariable po ... | 2019 | 31211672 |
| live calcium imaging of aedes aegypti neuronal tissues reveals differential importance of chemosensory systems for life-history-specific foraging strategies. | the mosquito aedes aegypti has a wide variety of sensory pathways that have supported its success as a species as well as a highly competent vector of numerous debilitating infectious pathogens. investigations into mosquito sensory systems and their effects on behavior are valuable resources for the advancement of mosquito control strategies. numerous studies have elucidated key aspects of mosquito sensory systems, however there remains critical gaps within the field. in particular, compared to ... | 2019 | 31208328 |
| resistance status of aedes aegypti to deltamethrin, malathion, and temephos in ecuador. | in ecuador, the status of insecticide resistance for aedes aegypti, the principal arboviral vector in the country, has not been previously evaluated. the aim of this research was to describe the resistance status of ae. aegypti to the principal insecticides used for vector control in provinces with high reports of arboviral clinical cases. this was a descriptive study performed on ae. aegypti collected from 2016 to 2017 in 14 localities of ecuador. the larvae were reared and tested using bioassa ... | 2019 | 31442135 |
| a survey for aedes aegypti in delaware and the virus-positive pool rates of aedes albopictus and aedes triseriatus for west nile and zika viruses. | the introduction of zika virus to the usa in 2015 engendered heightened interest in its known vectors. aedes aegypti is the primary vector, with ae. albopictus considered a potential secondary vector, together with several other possible marginal vectors. in delaware, ae. aegypti has been collected rarely, but no breeding populations were detected during past intensive statewide surveillance efforts. however, there is an abundance of ae. albopictus statewide. both species are container breeders ... | 2019 | 31442131 |
| field efficacy trials of aerial ultra-low-volume application of insecticides against caged aedes aegypti in mexico. | we evaluated the efficacy of aerial ultra-low-volume (ulv) insecticide spraying in field bioassays with caged aedes aegypti in may 2017 in puerto vallarta, jalisco, mexico. the insecticides tested included an organophosphate (mosquitocida uno ulv) and a neonicotinoid-pyrethroid combination (cielo). two ae. aegypti populations were evaluated: a field pyrethroid-resistant local strain (puerto vallarta) and an insecticide-susceptible laboratory strain (new orleans). knockdown after 1 h by both prod ... | 2019 | 31442128 |
| evaluation and comparison of spray equipment for indoor residual spraying. | the world health organization (who) has recently recommended indoor residual spraying (irs) as part of a vector control strategy to combat aedes-borne diseases, including dengue, chikungunya, and zika viruses. hand compression sprayers have been used in malaria prevention and control programs worldwide since the 1950s and are a standard for irs application. however, there are technological advances that should be considered to improve irs application (e.g., flow-control valves, rechargeable-batt ... | 2019 | 31442127 |
| semi-field evaluation of modified 00zzzero® traps with sticky paper to increase the collection efficacy of gravid aedes aegypti. | the 00zzzero® trap (0z) is a small black plastic container with permethrin and pyriproxyfen, designed and marketed to both attract and kill gravid aedes mosquitoes (unmodified trap ([umt] or modified trap [mt]). the 0z trap without the insecticide was modified with addition of a sticky paper, coated with an adhesive glue (mt) and evaluated for collection efficacy of released gravid mosquito, aedes aegypti (l.) in outdoor screened enclosures in st. augustine, in northeastern florida. the mean num ... | 2019 | 31442126 |
| influence of sex ratio and density on the comparative repellency of ir3535® against caged aedes, anopheles, and culex mosquitoes. | studies on topical repellent efficacy conducted with caged mosquitoes in the laboratory are important to both the development and regulation of insect repellents. guidelines for laboratory studies stipulate specific densities, sex ratios, and biting rates, whereas those for field studies are governmentally required before a promising repellent can be registered for human use. these protocols stipulate minimum biting rates alone. relatively little is known, however, about the influence of mosquit ... | 2019 | 31441773 |
| dynamics and diversity of bacteria associated with the disease vectors aedes aegypti and aedes albopictus. | aedes aegypti and aedes albopictus develop in the same aquatic sites where they encounter microorganisms that influence their life history and capacity to transmit human arboviruses. some bacteria such as wolbachia are currently being considered for the control of dengue, chikungunya and zika. yet little is known about the dynamics and diversity of aedes-associated bacteria, including larval habitat features that shape their tempo-spatial distribution. we applied large-scale 16s rrna amplicon se ... | 2019 | 31434963 |
| systematic identification and characterization of aedes aegypti long noncoding rnas (lncrnas). | long noncoding rnas (lncrnas) play diverse roles in biological processes. aedes aegypti (ae. aegypti), a blood-sucking mosquito, is the principal vector responsible for replication and transmission of arboviruses including dengue, zika, and chikungunya virus. systematic identification and developmental characterisation of ae. aegypti lncrnas are still limited. we performed genome-wide identification of lncrnas, followed by developmental profiling of lncrna in ae. aegypti. we identified a total o ... | 2019 | 31434910 |
| copper(ii)-binding induces a unique polyproline type ii helical structure within the ion-binding segment in the intrinsically disordered f-domain of ecdysteroid receptor from aedes aegypti. | reproduction of the dominant vector of zika and dengue diseases, aedes aegypti mosquito, is controlled by an active heterodimer complex composed of the 20-hydroxyecdysone receptor (ecr) and ultraspiracle protein. although a. aegypti ecr shares the structural and functional organization with other nuclear receptors, its c-terminus has an additional long f domain (aafecr). recently, we showed that the full length aafecr is intrinsically disordered with the ability to specifically bind divalent met ... | 2019 | 31433630 |
| identification of anti-flaviviral drugs with mosquitocidal and anti-zika virus activity in aedes aegypti. | zika virus (zikv), an emerging arbovirus belonging to the genus flavivirus, is transmitted by aedes mosquitoes. zikv infection can cause microcephaly of newborn babies and guillain-barré syndrome in adults. because no licensed vaccine or specific antiviral treatment is available for zikv infection, the most commonly used approach to control the spread of zikv is suppression of the mosquito vector population. a novel proposed strategy to block arthropod virus (arbovirus) transmission is based on ... | 2019 | 31430351 |
| detecting wmel wolbachia in field-collected aedes aegypti mosquitoes using loop-mediated isothermal amplification (lamp). | the world mosquito program uses wolbachia pipientis for the biocontrol of arboviruses transmitted by aedes aegypti mosquitoes. diagnostic testing for wolbachia in laboratory colonies and in field-caught mosquito populations has typically employed pcr. new, simpler methods to diagnose wolbachia infection in mosquitoes are required for large-scale operational use. | 2019 | 31416478 |
| the major oligosaccharyl transferase complex genes are not involved in dengue virus replication in aedes aegypti mosquitoes. | replication of the dengue virus (denv) genome occurs in a vesicle in the endoplasmic reticulum by a complex of host and viral proteins. two host proteins, stt3a and stt3b, as members of the oligosaccharyl transferase complex, have been implicated in playing structural roles in the vesicle in mammalian cells, and the absence of these proteins has been shown to decrease denv replication. aedes aegypti is the main vector of the virus and has been used previously as a model organism to study mosquit ... | 2019 | 31414286 |
| antibiotic resistant bacteria and commensal fungi are common and conserved in the mosquito microbiome. | the emerging and increasing prevalence of bacterial antibiotic resistance is a significant public health challenge. to begin to tackle this problem, it will be critical to not only understand the origins of this resistance but also document environmental reservoirs of antibiotic resistance. in this study we investigated the possibility that both colony and field caught mosquitoes could harbor antibiotic resistant bacteria. specifically, we characterized the antibiotic resistant bacterial populat ... | 2019 | 31412044 |
| midgut barriers prevent the replication and dissemination of the yellow fever vaccine in aedes aegypti. | to be transmitted to vertebrate hosts via the saliva of their vectors, arthropod-borne viruses have to cross several barriers in the mosquito body, including the midgut infection and escape barriers. yellow fever virus (yfv) belongs to the genus flavivirus, which includes human viruses transmitted by aedes mosquitoes, such as dengue and zika viruses. the live-attenuated yfv-17d vaccine has been used safely and efficiently on a large scale since the end of world war ii. early studies have shown, ... | 2019 | 31412040 |
| nature of complex network of dengue epidemic as a scale-free network. | dengue epidemic is a dynamic and complex phenomenon that has gained considerable attention due to its injurious effects. the focus of this study is to statically analyze the nature of the dengue epidemic network in terms of whether it follows the features of a scale-free network or a random network. | 2019 | 31406610 |
| host and viral mechanisms of congenital zika syndrome. | in 2015-2016, in the americas, and especially in northeast brazil, a significant number of cases of microcephaly and other congenital brain abnormalities were linked with an outbreak of zika virus (zikv) infection in pregnant women. while maternal symptoms of zikv are generally mild and self-limiting, clinical presentation in fetuses and newborns infected is extensive and includes microcephaly, decreased cortical development, atrophy and hypoplasia of the cerebellum and cerebellar vermis, arthro ... | 2019 | 31451049 |
| life history traits and predatory performance of belostoma anurum (hemiptera: belostomatidae), a biological control agent of disease vector mosquitoes. | understanding the life cycle and dietary requirements of laboratory-reared insects is critical for optimizing resources (including time) and can provide more reliable ecological basis for using such biological control agents in realistic programs. here, we evaluated the complete development and the predatory abilities of belostoma anurum (herrich-schäffer, 1848) (hemiptera: belostomatidae), an aquatic predator widely distributed in neotropical region, when reared at different diets. we firstly i ... | 2019 | 31446550 |
| exposure of mosquito (aedes aegypti) larvae to the water extract and lectin-rich fraction of moringa oleifera seeds impairs their development and future fecundity. | aedes aegypti control is a key component of the prophylaxis of dengue fever and other diseases. moringa oleifera seeds contain a water-soluble lectin (wsmol) with larvicidal and ovicidal activities against this insect. in this study, a. aegypti individuals were exposed at the third larval instar for 24 h to the water extract (0.1-1.0 mg/ml of protein) or lectin-rich fraction (0.05-0.6 mg/ml of protein) containing wsmol, and then their survival and development were followed for 9 days post-exposu ... | 2019 | 31446169 |
| mitochondrial glycerol phosphate oxidation is modulated by adenylates through allosteric regulation of cytochrome c oxidase activity in mosquito flight muscle. | the huge energy demand posed by insect flight activity is met by an efficient oxidative phosphorylation process that takes place within flight muscle mitochondria. in the major arbovirus vector aedes aegypti, mitochondrial oxidation of pyruvate, proline and glycerol 3-phosphate (g3p) represent the major energy sources of atp to sustain flight muscle energy demand. although adenylates exert critical regulatory effects on several mitochondrial enzyme activities, the potential consequences of alter ... | 2019 | 31446033 |
| deet and other repellents are inhibitors of mosquito odorant receptors for oviposition attractants. | in addition to its primary function as an insect repellent, deet has many "off-label" properties, including a deterrent effect on the attraction of gravid female mosquitoes. deet negatively affects oviposition sites. while deorphanizing odorant receptors (ors) using the xenopus oocyte recording system, we have previously observed that deet generated outward (inhibitory) currents on ors sensitive to oviposition attractants. here, we systematically investigated these inhibitory currents. we record ... | 2019 | 31446031 |
| increased akt signaling in the fat body of anopheles stephensi extends lifespan and increases lifetime fecundity through modulation of insulin-like peptides. | insulin-like peptides (ilps) and the insulin/insulin-like growth factor 1 signaling (iis) cascade regulate numerous physiological functions, including lifespan, reproduction, immunity, and metabolism, in diverse eukaryotes. we previously demonstrated that in female anopheles stephensi and aedes aegypti mosquitoes, activation of the iis cascade in the fat body led to a significant increase in lifespan. in this work, we elucidated two putative mechanisms in a. stephensi behind the observed lifespa ... | 2019 | 31445957 |
| heterologous production and functional characterization of ageritin, a novel type of ribotoxin highly expressed during fruiting of the edible mushroom agrocybe aegerita. | fungi produce various defense proteins against antagonists, including ribotoxins. these toxins cleave a single phosphodiester bond within the universally conserved sarcin-ricin loop of ribosomes and inhibit protein biosynthesis. here, we report on the structure and function of ageritin, a previously reported ribotoxin from the edible mushroom agrocybe aegerita the amino acid sequence of ageritin was derived from cdna isolated from the dikaryon a. aegerita aae-3 and lacks, according to in silico ... | 2019 | 31444206 |
| investigation of relative development and reproductivity fitness cost in three insecticide-resistant strains of aedes aegypti from thailand. | knockdown resistance (kdr) and detoxification enzymes are major resistance mechanisms in insecticide-resistant aedes aegypti throughout the world. persistence of the resistance phenotype is associated with high fitness of resistance alleles in the absence of insecticide pressure. this study determined the relative fitness cost of three insecticide-resistant strains of aedes aegypti-pmd, pmd-r, and upk-r-and a hybrid under similar laboratory conditions in the absence of insecticide. the pmd strai ... | 2019 | 31443487 |
| odorant receptors from culex quinquefasciatus and aedes aegypti sensitive to floral compounds. | mosquitoes rely heavily on the olfactory system to find a host for a bloodmeal, plants for a source of energy and suitable sites for oviposition. here, we examined a cluster of eight odorant receptors (ors), which includes one or, cquior1, previously identified to be sensitive to plant-derived compounds. we cloned 5 ors from culex quinquefasciatus and two ors from aedes aegypti, ie, cquior2, cquior4, cquior5, cquior84, cquior85, aaegor14, and aaegor15 and then deorphanized these receptors using ... | 2019 | 31442487 |
| first report on the transmission of zika virus by aedes (stegomyia) aegypti (l.) (diptera: culicidae) during the 2018 zika outbreak in india. | in a recent outbreak of zika virus (zikv) infection in jaipur city (rajasthan, india), a total of 159 cases were reported in september 2018. in order to identify vector responsible for zika transmission, mosquitoes were collected from houses with reported zika cases and nearby houses. a total of 108 pools containing 522 mosquitoes were tested for presence of zikv using rt-pcr and real time rt-pcr. we detected presence of zikv in three pools of aedes (stegomyia) aegypti (l.), out of a total of 79 ... | 2019 | 31442386 |
| new county records of aedes aegypti and aedes epactius in colorado. | in august and september 2017, we conducted mosquito surveillance in southeastern colorado by using ovitraps and larval sampling. the aim was to determine if there were established populations of aedes aegypti and ae. albopictus in the region. a single female ae. aegypti was reared from eggs collected in la junta, co, but ae. albopictus was not detected. three other species were reared from eggs and/or larvae: ae. epactius, culex restuans, and cx. pipiens. aedes aegypti and ae. epactius were dete ... | 2019 | 31442179 |
| fractional-dose yellow fever vaccination: how much more can we do with less? | climate change, deforestation, urbanization, and increased population mobility have made the risk of large outbreaks of yellow fever more likely than ever. yellow fever vaccine production barely meets demands. in this review, we address the causes of the recent yellow fever outbreaks, why fractional dose yellow fever vaccination works, the role of virus neutralizing antibodies in the protection against yellow fever, and the need for revaccination. | 2019 | 31335440 |
| using citizen science to enhance surveillance of aedes aegypti in arizona, 2015-17. | vector surveillance is an essential component of vector-borne disease prevention, but many communities lack resources to support extensive surveillance. the great arizona mosquito hunt (gamh) was a collaborative citizen science project conducted during 2015-17 to enhance surveillance for aedes aegypti in arizona. citizen science projects engage the public in scientific research in order to further scientific knowledge while improving community understanding of a specific field of science and the ... | 2019 | 31334498 |
| a novel densovirus isolated from the asian tiger mosquito displays varied pathogenicity depending on its host species. | mosquito-borne viral diseases (mbvds) continue to pose a significant global public health burden. mosquito control remains a core intervention strategy in integrated mosquito management (imm) programs to reduce the transmission of mbvds. mosquito densoviruses (mdvs) are mosquito-specific entomopathogenic viruses, and their attractive biological and pathogenic characteristics make mdvs potential biological control agents as alternatives to traditional chemical pesticides. however, different viral ... | 2019 | 31333635 |
| 'swimming mosquitoes': a key stepping stone to prevent dengue, zika and chikungunya: an educative experience in colima, mexico. | dengue, zika and chikungunya arboviruses (dzc), mainly transmitted by mosquito aedes aegypti, are global health public issues affecting 390 million people each year. in most endemic countries, vector control strategies have been focused on reducing breeding sites and adult mosquito populations. most health communication strategies have pointed out adult mosquito as the main responsible of the transmission, persuading people to eliminate domestic containers. however, it is not clear how should pe ... | 2019 | 31329869 |
| susceptibility and alterations by diflubenzuron in larvae of aedes aegypti. | benzoylphenyl ureas inhibit chitin synthesis and interfere with the molting process in arthropods. in this study, the effect of diflubenzuron on third-instar larvae of aedes aegypti was evaluated. the susceptibility to the product was determined, and the alterations generated were shown through light and electron microscopy. lc50 and lc90 were 0.23 and 0.47 ppm, respectively. the main alterations observed were the incapacity to complete the molt, a reduction of mobility, the fragmentation of the ... | 2019 | 31328823 |
| visual-olfactory integration in the human disease vector mosquito aedes aegypti. | mosquitoes rely on the integration of multiple sensory cues, including olfactory, visual, and thermal stimuli, to detect, identify, and locate their hosts [1-4]. although we increasingly know more about the role of chemosensory behaviors in mediating mosquito-host interactions [1], the role of visual cues is comparatively less studied [3], and how the combination of olfactory and visual information is integrated in the mosquito brain remains unknown. in the present study, we used a tethered-flig ... | 2019 | 31327719 |
| mosquito host-seeking regulation: targets for behavioral control. | female aedes aegypti mosquitoes require protein from blood to develop eggs. they have evolved a strong innate drive to find and bite humans and engorge on their blood. decades of research have revealed that attraction to hosts is suppressed for days after blood-feeding. during this time, females coordinate complex physiological changes, allowing them to utilize blood protein to develop eggs: clearing excess fluid, digesting protein, and egg maturation. how do mechanosensation, nutrient consumpti ... | 2019 | 31326312 |
| too "sexy" for the field? paired measures of laboratory and semi-field performance highlight variability in the apparent mating fitness of aedes aegypti transgenic strains. | evaluating and improving mating success and competitive ability of laboratory-reared transgenic mosquito strains will enhance the effectiveness of proposed disease-control strategies that involve deployment of transgenic strains. two components of the mosquito rearing process, larval diet quantity and aquatic environment - which are linked to physiological and behavioural differences in adults - are both relatively easy to manipulate. in mosquitoes, as for many other arthropod species, the quali ... | 2019 | 31324262 |
| hydrophobic nanoprecipitates formed by benzoylphenylureas and β-cyclodextrin inclusion compounds: synthesis, characterization and toxicity against aedes aegypti larvae. | the aim of this work was to synthesize and characterize the inclusion compounds formed by the complexation of β-cyclodextrin (βcd) with insecticides from the class of benzoylphenylureas (bpus), named novaluron (nov) and diflubenzuron (dif), beyond evaluate their larvicidal activity against aedes aegypti larvae. solid state characterization by ftir showed changes in the main peaks of bpus and βcd, suggesting the formation of inclusion compounds in solid phase. dta and tga thermal analysis showed ... | 2019 | 31321326 |
| mosquito vectors of arboviruses in french polynesia. | the circulation of arthropod-borne viruses (arboviruses) throughout the pacific is no exception in french polynesia (fp). we review here the mosquito vectors involved or potentially involved in the transmission of arboviruses in fp. we highlight aedes aegypti and aedes polynesiensis; species that are widely distributed in fp and whose ability to transmit dengue, zika and chikungunya viruses is well known. in addition, we discuss the contribution of those species and the abundant culex annulirost ... | 2019 | 31316821 |
| evaluation of inflammatory skin infiltrate following aedes aegypti bites in sensitized and non-sensitized mice reveals saliva-dependent and immune-dependent phenotypes. | during probing and blood feeding, haematophagous mosquitoes inoculate a mixture of salivary molecules into their vertebrate hosts' skin. in addition to the anti-haemostatic and immunomodulatory activities, mosquito saliva also triggers acute inflammatory reactions, especially in sensitized hosts. here, we characterize the oedema and the cellular infiltrate following aedes aegypti mosquito bites in the skin of sensitized and non-sensitized balb/c mice by flow cytometry. ae. aegypti bites induced ... | 2019 | 31315156 |
| agbr1 antibodies delay lethal aedes aegypti-borne west nile virus infection in mice. | west nile virus (wnv) is transmitted by mosquitoes and can cause severe disease, including meningoencephalitis. agbr1 is a mosquito salivary protein that enhances aedes aegypti mosquito-borne zika virus pathogenesis in mice. here, we show that agbr1 antibodies reduce the initial west nile viral load and delay lethal infection after feeding by an infected aedes aegypti mosquito. targeting agbr1 may therefore be incorporated into strategies to prevent mosquito-transmitted west nile virus infection ... | 2019 | 31312526 |
| natural vertical transmission of zika virus in larval aedes aegypti populations, morelos, mexico. | we characterized natural vertical transmission of zika virus in pools of aedes aegypti larvae hatched from eggs collected in jojutla, morelos, mexico. of the 151 pools analyzed, 17 tested positive for zika virus rna; infectious zika virus was successfully isolated from 1 of the larvae pools (31n) in c6/36 cells. real-time quantitative pcr and indirect immunofluorescence assays confirmed the identity of the isolate, named zika virus isolate 31n; plaque assays in vero cells demonstrated the isolat ... | 2019 | 31310224 |
| expression of bacillus thuringiensis toxin cyt2ba in the entomopathogenic fungus beauveria bassiana increases its virulence towards aedes mosquitoes. | the entomopathogenic fungus beauveria bassiana has been widely used to kill mosquito larvae and adults in the laboratory and field. however, its slow action of killing has hampered its widespread application. in our study, the b. bassiana fungus was genetically modified to express the bacillus thuringiensis (bt) toxin cyt2ba to improve its efficacy in killing mosquitoes. | 2019 | 31306427 |
| ai- modelling of molecular identification and feminization of wolbachia infected aedes aegypti. | the genetic control strategies of vector borne diseases includes the replacement of a vector population by "disease-refractory" mosquitoes and the release of mosquitoes with a gene to control the vector's reproduction rates. wolbachia are common intracellular bacteria that are found in arthropods and nematodes. wolbachia infected male mosquitos have been used in different experimental trials around the world to suppress the target population of aedes aegypti and this genetic control strategy has ... | 2019 | 31302148 |
| eucalyptus camaldulensis properties for use in the eradication of infections. | eucalyptus camaldulensis (e. camaldulensis), called the eucalyptus has so many characteristics such as antimicrobial features. common names include red gum, red chewing gum, river chewing gum, red chewing gum. its class is eucalyptus, which is comprised of 800 species worldwide, but three or four species are found in australia. this tree generally grows on the edge of rivers with continuous or seasonal water. most of the gray clay soils run along the riverside and are exposed to frequent floods, ... | 2019 | 31300120 |
| tracking genetic invasions: genome-wide single nucleotide polymorphisms reveal the source of pyrethroid-resistant aedes aegypti (yellow fever mosquito) incursions at international ports. | biological invasions are increasing globally in number and extent despite efforts to restrict their spread. knowledge of incursion pathways is necessary to prevent new invasions and to design effective biosecurity protocols at source and recipient locations. this study uses genome-wide single nucleotide polymorphisms (snps) to determine the origin of 115 incursive aedes aegypti(yellow fever mosquito) detected at international ports in australia and new zealand. we also genotyped mosquitoes at th ... | 2019 | 31297145 |
| location, seasonal and functional characteristics of water-holding containers with juvenile aedes albopictus in urban southern taiwan: a cross-sectional study. | urban kaohsiung city (kc), in southern taiwan, has experienced annual dengue epidemics for decades despite considerable vector control efforts. substantial research has been undertaken to characterize aedes aegypti breeding habitats, but no systematic assessment has been completed for aedes albopictus present in kc. | 2019 | 31294804 |
| development of the major arboviral vector aedes aegypti in urban drain-water and associated pyrethroid insecticide resistance is a potential global health challenge. | aedes aegypti were found developing in the water in open public drains (drain-water, dw) in jaffna city in northern sri lanka, a location where the arboviral diseases dengue and chikungunya are endemic. | 2019 | 31287014 |
| a mosquito workshop and community intervention: a pilot education campaign to identify risk factors associated with container mosquitoes in san pedro sula, honduras. | dengue poses a significant public health threat and results in ~96 million clinical cases every year. central america is a region burdened by neglected tropical diseases, including dengue. the primary vectors of dengue, aedes aegypti and aedes albopictus, are widely distributed in honduras. additionally, sustained and consistent mosquito control is lacking in the country. successful control of container mosquitoes relies heavily on participation from community leaders, stakeholders, and the comm ... | 2019 | 31284544 |
| intercepted mosquitoes at new zealand's ports of entry, 2001 to 2018: current status and future concerns. | mosquito vectors are extending their range via international travel and trade. climate change makes new zealand an increasingly suitable environment for less tropically adapted exotic mosquito vectors to become established. this shift will add a multiplier effect to existing risks of both the establishment of new species and of resident exotic species extending into new areas. we describe trends in the border interceptions of exotic mosquitoes and evaluate the role of imported goods as a pathway ... | 2019 | 31284464 |
| vertical transmission of zika virus (flaviviridae, flavivirus) in amazonian aedes aegypti (diptera: culicidae) delays egg hatching and larval development of progeny. | zika virus (zikv) has emerged as a globally important arbovirus and has been reported from all states of brazil. the virus is primarily transmitted to humans through the bite of an infective aedes aegypti (linnaeus, 1762) or aedes albopictus (skuse, 1895). however, it is important to know if zikv transmission also occurs from ae. aegypti through infected eggs to her offspring. therefore, a zikv and dengue virus (denv) free colony was established from eggs collected in manaus and maintained until ... | 2019 | 31278737 |
| using genetic variation in aedes aegypti to identify candidate anti-dengue virus genes. | transcriptomic profiling has generated extensive lists of genes that respond to viral infection in mosquitoes. these gene lists contain two types of genes; (1) those that are responsible for the insect's natural antiviral defense mechanisms, including some known innate immunity genes, and (2) genes whose change in expression may occur simply as a result of infection. as genetic modification tools for mosquitoes continue to improve, the opportunities to make refractory insects via allelic replace ... | 2019 | 31272403 |
| spatial distribution of aedes aegypti (diptera: culicidae) in vulnerable areas for the transmission of arboviruses. | areas at risk of transmission of arboviruses have been monitored using ovitraps. this study aimed to evaluate the spatial distribution of aedes aegypti in vulnerable areas for the transmission of arboviruses and assess the influence of climatic conditions on the infestation of these culicids. | 2019 | 31271613 |
| insecticide resistance status of aedes aegypti and aedes albopictus mosquitoes in papua new guinea. | aedes aegypti and ae. albopictus are important vectors of infectious diseases, especially those caused by arboviruses such as dengue, chikungunya and zika. aedes aegypti is very well adapted to urban environments, whereas ae. albopictus inhabits more rural settings. pyrethroid resistance is widespread in these vectors, but limited data exist from the southwest pacific region, especially from melanesia. while aedes vector ecology is well documented in australia, where incursion of ae. albopictus ... | 2019 | 31269965 |
| aedes vector surveillance in the southeastern united states reveals growing threat of aedes japonicus japonicus (diptera: culicidae) and aedes albopictus. | mosquito-borne diseases are on the rise globally, and have the potential to thrive along the gulf coast of the united states, where subtropical conditions may facilitate the introduction or movement of mosquito vectors. despite surveillance efforts, aedes aegypti (l.) had not been detected in the gulf state of alabama for nearly three decades. the detection of ae. aegypti in alabama may suggest remnant or reemergent populations of this vector. we conducted adult sampling between may and august o ... | 2019 | 31268136 |
| a salivary protein of aedes aegypti promotes dengue-2 virus replication and transmission. | although dengue is the most prevalent arthropod-borne viral disease in humans, no effective medication or vaccine is presently available. previous studies suggested that mosquito salivary proteins influence infection by the dengue virus (denv) in the mammalian host. however, the effects of salivary proteins on denv replication within the aedes aegypti mosquito remain largely unknown. in this study, we investigated the effect of a specific salivary protein (named aasg34) on denv serotype 2 (denv2 ... | 2019 | 31265906 |
| inhibition of juvenile hormone synthesis in mosquitoes by the methylation inhibitor 3-deazaneplanocin a (dznep). | juvenile hormone (jh), synthesized by the corpora allata (ca), controls development and reproduction in mosquitoes through its action on thousands of jh-responsive genes. these jh-dependent processes can be studied using tools that increase or decrease jh titers in vitro and in vivo. juvenile hormone acid methyl transferase (jhamt) is a critical jh biosynthetic enzyme. jhamt utilizes the methyl donor s-adenosyl-methionine (sam) to methylate farnesoic acid (fa) into methyl farnesoate (mf), releas ... | 2019 | 31265905 |
| combinations of plant essential oil based terpene compounds as larvicidal and adulticidal agent against aedes aegypti (diptera: culicidae). | insecticidal plant-based compound(s)in combinations may show synergistic or antagonistic interactions against insect pest. considering the rapid spread of the aedes borne diseases and increasing resistance among aedes population against conventional insecticides, twenty-eight combinations of plant essential oil-based terpene compounds were prepared and tested against larval and adult stages ofaedes aegypti. initially five plant essential oils (eos) were assessed for their larvicidal and adultici ... | 2019 | 31263222 |
| pluripotency of wolbachia against arboviruses: the case of yellow fever. | background: yellow fever outbreaks have re-emerged in brazil during 2016-18, with mortality rates up to 30%. although urban transmission has not been reported since 1942, the risk of re-urbanization of yellow fever is significant, as aedes aegypti is present in most tropical and sub-tropical cities in the world and still remains the main vector of urban yfv. although the yfv vaccine is safe and effective, it does not always reach populations at greatest risk of infection and there is an acknowle ... | 2019 | 31259313 |