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fructose variation in the dengue vector, aedes aegypti, during high and low transmission seasons in the mae sot region of thailand.to understand the potential for facultative sugar feeding by aedes aegypti, an important vector of dengue viruses, we evaluated seasonal and villagewide variation in sugar feeding during high- and low-dengue transmission seasons (rainy and dry seasons, respectively) in the mae sot region of thailand. these seasons in thailand are represented by different periods of flowering plant phenology. although overall sugar feeding among female and male mosquitoes was low (ranging from 0.60 to 7.53 microg ...200516033119
ant behaviour and seed morphology: a missing link of myrmecochory.seed dispersal by ants (myrmecochory) is mediated by the presence of a lipid-rich appendage (elaiosome) on the seed that induces a variety of ants to collect the diaspores. when seeds mature or fall onto the ground, these ant species transport them to their nest. after eating the elaiosome, the seed is discarded in nest galleries or outside, in the midden or farther away, where seeds can potentially germinate. the final location of seeds with their elaiosomes removed was evaluated to assess the ...200516044350
comparative study of the conformational lock, dissociative thermal inactivation and stability of euphorbia latex and lentil seedling amine oxidases.the thermal stability of copper/quinone containing amine oxidases from euphorbia characias latex (elao) and lentil seedlings (lsao) was measured in 100 mm potassium phosphate buffer (ph 7.0) following changes in absorbance at 292 nm. elao was shown to be about 10 degrees c more stable than lsao. the dissociative thermal inactivation of elao was studied using putrescine as substrate at different temperatures in the range 47-70 degrees c, and a "conformational lock" was developed using the theory ...200516096724
inhibition of p-glycoprotein transport activity in a resistant mouse lymphoma cell line by diterpenic lactones.multidrug resistance (mdr) is believed to be a major reason for the failure of cancer treatment. it is in most cases caused by the activity of the various abc transporters, multidrug resistance (mdr) gene-encoded p-glycoproteins that pump anticancer drugs out of the cells. p-glycoprotein (p-gp) and multidrug resistance-associated protein (mrp1) are the most important and widely studied members of the abc superfamily of transporters. the ability of four diterpenic lactones isolated from euphorbia ...200516101136
evaluation of some medicinal plant extracts for antidiarrhoeal activity.the antidiarrhoeal effect of seven plant extracts namely: the aerial parts of euphorbia paralias l. (ep), bidens bipinnata l. (bb), cynachum acutum l. (cyac), diplotaxis acris (forssk.) boiss (da), convolvulus fatmensis (cf) and schouwia thebaica webb (st) and the leaves of plantago major l. (pm), was evaluated on castor oil-induced diarrhoea, gastrointestinal movement in rats (charcoal meal) and on the motility of duodenum isolated from freshly slaughtered rabbits. a significant antidiarrhoeal ...200516114083
fine carbohydrate recognition of euphorbia milii lectin.glycans are key structures involved in biological processes such as cell attachment, migration, and invasion. information coded on cell-surface glycans is frequently deciphered by proteins, as lectins, that recognize specific carbohydrate topology. here, we describe the fine carbohydrate specificity of euphorbia milii lectin (eml). competitive assays using various sugars showed that galnac was the strongest inhibitor, and that the hydroxyl axial position of c4 and acetamido on c2 of galnac are c ...200516122701
anti-bacterial activity of euphorbia fusiformis--a rare medicinal herb.euphorbia fusiformis buch.-ham. ex. d.don (euphorbiaceae) is a rare medicinal herb. aqueous and organic solvent extracts of the leaves and rootstocks were investigated for anti-bacterial properties by using disc diffusion and well-in agar methods, against pathogenic strains of gram positive (bacillus subtilis and staphylococcus aureus) and gram negative bacteria (escherichia coli, klebsiella pneumoniae, proteus vulgaris, pseudomonas aeruginosa, salmonella typhii a and salmonella typhii b). the d ...200516159702
flavonoids that mimic human ligands from the whole plants of euphorbia lunulata.in our investigation of a cell proliferation-based screening assay using human ligand-dependent cell lines for medicinal herbal extracts, the acetone extract of the whole plants of euphorbia lunulata (el) was observed for its proliferation activity for insulin- and interleukin-10 (il-10)-dependent cell lines. fractionation of the active extract led to the isolation of one new flavonoid galactoside, quercetin 3-o-(2'',3''-digalloyl)-beta-d-galactopyranoside (1), and four known ones, quercetin 3-o ...200515744103
antinociceptive diterpene from euphorbia decipiens.one myrsinol-type diterpene ester (1) isolated from euphorbia decipiens was evaluated for analgesic activity in the acetic acid induced writhing test in mice. different dose (5-20 mg/kg i.p.) of the compound showed significant antinociceptive activity, which was comparable to standard analgesic drugs, aspirin and ibuprofen (100 mg/kg i.p.).200515752637
three new jatrophone-type diterpenoids from euphorbia helioscopia.three new jatrophone-type diterpenoids, euphoheliosnoids a-c, together with two known related compounds, were isolated from the chinese medicinal plant euphorbia helioscopia l. the structures including relative stereochemistry of the new compounds were elucidated by spectroscopic methods and by comparison with known related compounds.200515770554
lathyranoic acid a: first secolathyrane diterpenoid in nature from euphorbia lathyris.[structures: see text] lathyranoic acid a (1), the first secolathyrane diterpenoid with an unprecedented skeleton, and a new diterpenoid euphorbia factor l11 (2) were isolated from the seeds of euphorbia lathyris. their structures were elucidated by spectroscopic analysis and chemical methods. a biogenetic route involving an enzymatic baeyer-villiger oxidation as the key step was postulated for the transformation of 2 to 1 and mimicked by an unusual chemical baeyer-villiger oxidation.200515787511
a molecular phylogeny of the hawkmoth genus hyles (lepidoptera: sphingidae, macroglossinae).the hawkmoth genus hyles is one of 15 genera in the subtribe choerocampina of the subfamily macroglossinae. due to a remarkable uniformity, morphological characters usually used to identify and classify lepidoptera at the species level cannot be used in this genus. instead, we used dna sequences comprising about 2300 bp derived from the mitochondrial genes cox i, cox ii, and trna-leucine to elucidate the phylogeny of hyles. the results corroborate the monophyly of hyles but conflict with previou ...200515804414
pep005, a selective small-molecule activator of protein kinase c, has potent antileukemic activity mediated via the delta isoform of pkc.ingenol 3-angelate (pep005) is a selective small molecule activator of protein kinase c (pkc) extracted from the plant euphorbia peplus, whose sap has been used as a traditional medicine for the treatment of skin conditions including warts and cancer. we report here that pep005 also has potent antileukemic effects, inducing apoptosis in myeloid leukemia cell lines and primary acute myeloid leukemia (aml) cells at nanomolar concentrations. of importance, pep005 did not induce apoptosis in normal ...200515845901
euphorbia thymifolia suppresses herpes simplex virus-2 infection by directly inactivating virus infectivity.1. the ethyl acetate (etoac) extract and 3-o-galloyl-4,6-(s)-hexahydroxydiphenoyl-d-glucose (3og46hg) of euphorbia thymifolia linnea have been shown to exhibit anti-herpes simplex virus (hsv)-2 activity in vitro. in the present study, we investigated the mode of action of these two compounds in suppressing hsv-2 multiplication. 2. the results demonstrated that the etoac extract and 3og46hg affected virus infectivity in a dose-dependent manner. the etoac extract significantly reduced virus infect ...200515854140
cytotoxic diterpenoids from the roots of euphorbia ebracteolata.three new diterpenoids, yuexiandajisu d (1), e (2) and f were isolated from the roots of euphorbia ebracteolata, along with eight known diterpenoids, jolkinolide b (4), jolkinolide a, ent-11alpha-hydroxyabieta-8(14),13(15)-dien-16,12alpha-olide (6), ent-(13s)-hydroxyatis-16-ene-3,14-dione, ent-3beta,(13s)-dihydroxyatis-16-en-14-one, ent-3-oxokaurane-16alpha,17-diol, ent-16alpha,17-dihydroxyatisan-3-one and ent-atisane-3beta,16alpha,17-triol. the structures of all compounds were deduced using spe ...200515856412
contribution of natural products to the discovery of the transient receptor potential (trp) channels family and their functions.members of the transient receptor potential (trp) family of nonselective cation channels are involved in several pathological and physiological conditions. the search for the molecular targets for naturally occurring substances, especially from plants, allowed the characterization of many trp channels. in fact, attempts to understand the hot and painful action of the vanillyl group containing compounds capsaicin (from capsicum sp.) and its ultrapotent analogue resiniferatoxin (rtx, from euphorbi ...200515866319
cytotoxicity of plants used in traditional medicine in yemen.twenty-five extracts obtained from 14 plant species used in the traditional medicine in yemen have been screened for cytotoxic activity against human ecv-304 cells. extracts of dracaena cinnabari, eucalyptus camaldulensis, euclea divinorum, euphorbia cactus, pulicaria crispa, and withania somnifera displayed a remarkable activity.200515890471
poinsettia latent virus is not a cryptic virus, but a natural polerovirus-sobemovirus hybrid.the biochemical and genetic features of poinsettia latent virus (pnlv, formerly named poinsettia cryptic virus), which is spread worldwide in commercial cultivars of euphorbia pulcherrima without inducing symptoms, have been determined using virus-purification, immunological techniques, electron microscopy, cloning, and sequencing. pnlv was found to be a chimeric virus with one 4652 bases, plus strand rna showing a close relationship to poleroviruses within the first three quarters of its genome ...200515892965
immunosuppressive properties of an ethyl acetate fraction from euphorbia royleana.the objective of the study was to investigate the activity of the ethyl acetate (ea) fraction of euphorbia royleana latex on cellular and humoral-mediated immune responses and phagocytic function of the cells of the reticuloendothelial system in mice. oral administration of ea at doses of 50, 100 and 200 mg/kg p.o. in mice with sheep red blood cells (srbc) as an antigen-inhibited both the delayed-type hypersensitivity reaction and the production of circulating antibody titre. reduction of cd4+ t ...200515894125
the toxicity of four native indian plants: effect on ache and acid/alkaline phosphatase level in fish channa marulius.the latex of four plants viz. euphorbia royleana, jatropha gossypifolia (euphorbiaceae), nerium indicum and thevetia peruviana (apocynaceae) caused significant reduction in acid/alkaline phosphatase activity and anti-acetylcholinesterase activity in nervous tissue of freshwater air breathing fish channa marulius. the reduction in the activity of both phosphatases and ache were time as well as dose dependent.200515910912
lipids as regulators of the activity of transient receptor potential type v1 (trpv1) channels.after 7 years from its cloning, the transient receptor potential vanilloid type-1 (trpv1) channel remains the sole membrane receptor mediating the pharmacological effects of the hot chilli pepper pungent component, capsaicin, and of the euphorbia toxin, resiniferatoxin. yet, this ion channel represents one of the most complex examples of how the activity of a protein can be regulated. among the several chemicophysical stimuli that can modulate trpv1 permeability to cations, endogenous lipids app ...200515936040
reactions of plant copper/topaquinone amine oxidases with n6-aminoalkyl derivatives of adenine.plant copper/topaquinone-containing amine oxidases (caos, ec 1.4.3.6) are enzymes oxidising various amines. here we report a study on the reactions of caos from grass pea (lathyrus sativus), lentil (lens esculenta) and euphorbia characias, a mediterranean shrub, with n6-aminoalkyl adenines representing combined analogues of cytokinins and polyamines. the following compounds were synthesised: n6-(3-aminopropyl)adenine, n6-(4-aminobutyl)adenine, n6-(4-amino-trans-but-2-enyl) adenine, n6-(4-amino-c ...200515968819
a dna microarray for the authentication of toxic traditional chinese medicinal plants.a silicon-based dna microarray was designed and fabricated for the identification of toxic traditional chinese medicinal plants. species-specific oligonucleotide probes were derived from the 5s ribosomal rna gene of aconitum carmichaeli, a. kusnezoffi, alocasia macrorrhiza, croton tiglium, datura inoxia, d. metel, d. tatula, dysosma pleiantha, dy. versipellis, euphorbia kansui, hyoscyamus niger, pinellia cordata, p. pedatisecta, p. ternata, rhododendron molle, strychnos nux-vomica, typhonium div ...200515971136
the molluscicidal activities of some euphorbia milii hybrids against the snail indoplanorbis exustus.the objective of this study was to observe the molluscicidal activities of euphorbia milli, known as "poysean" in thailand, against indoplanorbis exustus. latex from 12 different e. milii hybrids was screened for its molluscicidal activities. indoplanorbis exustus were exposed for 24 and 48 hours to the latex at various concentrations ranging from 6 to 25 ppm and mortality rates were recorded. eight hybrids of latex were effective. the six most effective hybrids were e. milii dang-udom, e. milii ...200516438208
alterations in carbohydrates and the protein metabolism of the harmful freshwater vector snail lymnaea acuminata induced by the euphorbia tirucalli latex extract.to know the short- as well as long-term effect of aqueous latex extracts of euphorbia tirucalli on carbohydrate and protein metabolism, the snail lymnaea acuminata was exposed to sublethal doses of 0.37 and 0.55 mg/l for a 24-h and 0.20 and 0.31 mg/l for a 96-h exposure period. significant (p<0.05) alterations in the glycogen, pyruvate, lactate, total protein, and free amino acid level, as well as in the activity of enzyme lactic dehydrogenase, succinic dehydrogenase, cytochrome oxidase, proteas ...200516307980
a new bisabolane sesquiterpenoid from euphorbia chrysocoma.the new sesquiterpenoid (6r)-2-chloro-6-[(1s)-1,5-dimethylhex-4-en-1-yl]-3-methylcyclohex-2-en-1-one (1), together with ten known compounds, (6r)-6-[(1s)-1,5-dimethylhex-4-en-1-yl]-3-methylcyclohex-2-en-1-one (2), bauerenol acetate (3), lupenone (4), alpha-amyrenone (5), beta-sitosterol (6), stigmasterol (7), beta-amyrin (8), ursolic acid (9), betulinic acid (10), scopolin (11), have been isolated from the roots of euphorbia chrysocoma lévl. et vant. their structures have been elucidated by spec ...200516308205
isolation and characterization of methyl esters and derivatives from euphorbia kansui (euphorbiaceae) and their inhibitory effects on the human sgc-7901 cells.in this study, the inhibitory activity of the methyl esters and derivatives extracted from euphorbia kansui (euphorbiaceae) and their effect on apoptosis and cell cycle distribution in the human gastric cancer cell line (sgc-7901) were evaluated.200516401398
reversible thermal inactivation and conformational states in denaturant guanidinium of a calcium-dependent peroxidase from euphorbia characias.the changes in the heme environment and overall structure occurring during reversible thermal inactivation and in denaturant guanidinium of euphorbia characias latex peroxidase (elp) were investigated in the presence and absence of calcium ions. native active enzyme had an absorption spectrum typical of a quantum-mixed spin ferric heme protein. after 40 min at 60 degrees c elp was fully inactivated showing the spectroscopic behavior of a pure hexacoordinate low-spin protein. the addition of ca2+ ...200516336996
allelopathic effects of aconitic acid on wild poinsettia (euphorbia heterophylla) and morningglory (ipomoea grandifolia).high infestations of alexandergrass (brachiaria plantaginea) in experimental area have reduced seedbank of some weed species in soil at a greater degree compared to those obtained with the use of an efficient herbicide. aconitic acid (aa) has been identified in those plants in high concentration. thus, two experiments were carried out in the laboratory to determine the effects of pure aa on weed seed germination and on endophytic fungi in wild poinsettia (euphorbia heterophylla) and morningglory ...200515656164
multiple resistance of acetolactate synthase and protoporphyrinogen oxidase inhibitors in euphorbia heterophylla biotypes.resistance to acetolactate synthase (als)-inhibiting herbicides in brazil has been documented for six species. the probability to select biotypes of euphorbia heterophylla (epphl) with multiple resistance increases in the same order of magnitude as the use of other herbicides belonging to only one mechanism of action. the objectives of this work were to evaluate the distribution of resistant populations (r) in the states of the parana and santa catarina; to determine the existence of populations ...200515656167
population dynamics of weeds in no-tillage and conventional crop systems.population dynamics of weeds in successive maize and bean crops were evaluated in two soil management systems (conventional and no-tillage), for two maize applications (grain and silage), and in four consecutive growing seasons. every year, conventional tillage consisted in plowing and harrowing before sowing. in no-tillage, chemical weed desiccation was made with the mixture glyphosate + 2.4-d. to control weeds, the mixture fluazifop-p-butil + fomesafen was applied on the bean crop in all the p ...200515656169
effects of hand weeding strip and nitrogen fertilizer on corn plants.the objective of the present research was to evaluate effects of different strip weed control associated with nitrogen fertilizer on corn applied after planting. the experiment was set and conducted in botucatu, são paulo state, brazil, and the hybrid planted was dekalb 333-b. a completely randomized block design with four replications was used. experimental plots were disposed as a factorial scheme 2 x 2 x 4, constituted by two types of weeding on row (with or without manual hoeing), two types ...200515656170
influence of type and amount of straw cover on weed emergence.this research was undertaken during 2003-2004 growing season to evaluate the effects of type [forage sorghum "hybrid cober exp" (sorghum bicolor x sorghum sudanense), forage millet (pennisetum americanum "var. bn2"), finger millet (eleusine coracana), and st lucia grass (brachiaria brizantha)] and amount of straw cover (5.5 and 3.0 t ha(-1)) upon the emergence of bidens pilosa, chamaesyce spp., amaranthus spp., and commelina benghalensis, under field conditions of the brazilian cerrado, in the r ...200515656176
[toxic phytodermatitis caused by euphorbia helioscopia l. (sun spurge)].a 6-year-old patient presented with linear erythema and bullae on the face. the lesions developed after playing with plants the day before. the plant was identified as euphorbia helioscopia l. (sun spurge). the sun spurge belongs to the euphorbiaceae plant family. these plants produce a typical milky juice that causes toxic reactions following contact with skin and mucous membranes. in the literature several cases of toxic dermatitis caused by plants of the euphorbiaeae family have been describe ...200515662536
traditional phytotherapy in central italy (marche, abruzzo, and latium).in this study, the more significant results of extensive ethnopharmacobotanical research carried out by the author in the years 1977-2000 in 175 localities of three regions of central italy (marche, abruzzo, and latium) have been reported and compared. the usages of 80 species belonging to 36 families are described, of which 71 were used in human therapy and 29 in veterinary medicine. uses are suited with the number of localities in which they have been mentioned. among the wild plant mainly sti ...200515664457
screening of anti-helicobacter pylori herbs deriving from taiwanese folk medicinal plants.in this study, extracts from 50 taiwanese folk medicinal plants were examined and screened for anti-helicobacter pylori activity. ninety-five percent ethanol was used for herbal extraction. paederia scandens (lour.) merr. (psm), plumbago zeylanica l. (pzl), anisomeles indica (l.) o. kuntze (aiok), bombax malabaricum dc. (bmdc) and alpinia speciosa (j. c. wendl.) k. schum. (asks) and bombax malabaricum dc. (bmdc) all demonstrated strong anti-h. pylori activities. the minimum inhibitory concentrat ...200515681161
dichogamy and sexual dimorphism in floral traits in the andromonoecious euphorbia boetica.euphorbia boetica (euphorbiaceae) is a functional andromonoecious species that shows both intra- and interfloral dichogamy, hermaphrodite cyathia being protogynous. sexual dimorphism of the cyathia of e. boetica is examined according to their gender and arrangement on the inflorescence.200515701661
two new diterpene polyesters from euphorbia decipiens.two new myrsinol-type diterpene polyesters 3,5,13,17-tetra-o-acetyl-7-o-benzoyl-15-hydroxymyrsinol (1) and 3,5,13,17-tetra-o-acetyl-7-o-butanoyl-13-hydroxymyrsinol (2), with a tricyclic carbon skeleton have been isolated from euphorbia decipiens boiss. & buhse. the structure elucidation of the isolated compounds was based primarily on hreims, eims, ir, uv, id-, and 2d-nmr analyses, including cosy, hmqc, hmbc, and noesy correlations. compounds 1 and 2 also showed activity against urease enzyme.200515702640
explosive seed dispersal in two perennial mediterranean euphorbia species (euphorbiaceae).the distance of explosive dispersal, its pattern in time, and the relative importance of autochory have been studied in two diplochorous species: euphorbia boetica and e. nicaeensis. the seeds of e. boetica released by explosive dispersal reached a median distance of 156 cm and a maximum of almost 8 m, while the distances reached by the seeds of e. nicaeensis were lower: a median of 132 cm and a maximum of 5 m. the differences in explosive dispersal distance between species seem to depend on bot ...200521652429
extinction threat in the pedilanthus clade (euphorbia, euphorbiaceae), with special reference to the recently rediscovered e. conzattii (p. pulchellus).the type locality of the slipper spurge euphorbia conzattii has been in doubt because the 1917 type is a mixed collection with vague label data. in recent field work, the species was found on cerro espino, pochutla district, oaxaca, mexico. we used the method for evaluation of risk of extinction for mexican wild species (mer), required to protect a species under mexican law, to assess the conservation status of e. conzattii and found it to be endangered. we discuss the mixture in the type of thi ...200521652441
piscicidal and anti-acetylcholinesterase activity of euphorbia royleana stem bark extracts against freshwater common predatory fish channa punctatus.the present paper deals with the piscicidal activity of different solvent extracts of euphorbia royleana stem bark against freshwater predatory fish channa punctatus, which is commonly present in shrimp and carp culture ponds. the rank of order of toxicity of different solvent extract was: diethyl ether (lc(50) (96h) 31.76mg dw/l) > chloroform (lc(50) (96h) 56.26mg dw/l) > methanol (lc(50) (96h) 56.80mg dw/l) > acetone (lc(50) (96h) 65.77mg dw/l). there was a significant (p < 0.05) negative corr ...200421782734
toxic effect of two common euphorbiales latices on the freshwater snail lymnaea acuminata.the aqueous and serially purified latex extracts of plants euphorbia pulcherima and euphorbia hirta (family euphorbiaceae) have potent molluscicidal activity. sub-lethal doses (40 and 80% of lc(50)) of aqueous and partially purified latex extracts of both the plants also significantly alter the levels of total protein, total free amino acid, nucleic acid (dna and rna) and the activity of enzyme protease and acid and alkaline phosphatase in nervous tissue of the snail lymnaea acuminata in time an ...200421782684
fusarium foetens, a new species pathogenic to begonia elatior hybrids (begonia x hiemalis) and the sister taxon of the fusarium oxysporum species complex.a new disease recently was discovered in begonia elatior hybrid (begonia × hiemalis) nurseries in the netherlands. diseased plants showed a combination of basal rot, vein yellowing and wilting and the base of collapsing plants was covered by unusually large masses of fusarium macroconidia. a species of fusarium was isolated consistently from the discolored veins of leaves and stems. it differed morphologically from f. begoniae, a known agent of begonia flower, leaf and stem blight. the fusarium ...200421148861
comparison of supercritical fluid and soxhlet extractions for the quantification of hydrocarbons from euphorbia macroclada.this study compares conventional soxhlet extraction and analytical scale supercritical fluid extraction (sfe) for their yields in extracting of hydrocarbons from arid-land plant euphorbia macroclada. the plant material was firstly sequentially extracted with supercritical carbon dioxide, modified with 10% methanol (v/v) in the optimum conditions that is a pressure of 400atm and a temperature of 50 degrees c and then it was sonicated in methylene chloride for an additional 4h. e. macroclada was s ...200418969630
toxic effect of stem bark and leaf of euphorbia hirta plant against freshwater vector snail lymnaea acuminata.the aqueous stem bark and leaf extracts of plant euphorbia hirta (family-euphorbiaceae) have potent molluscicidal activity. sub-lethal doses (40% and 80% of lc50) of aqueous stem bark and leaf extracts of this plant also significantly (p<0.05) alter the levels of total protein, total free amino acid, nucleic acids (dna and rna) and the activity of enzyme protease and acid and alkaline phosphatase in various tissues of the vector snail lymnaea acuminata in time and dose dependent manner. euphorbi ...200415722098
a new sesquiterpene-coumarin ether and a new abietane diterpene and their effects as inhibitors of p-glycoprotein.a new sesquiterpene-coumarin ether (5'beta,9'alpha,10'alpha)-7-0-(3alpha-methoxy-8'(12')-drimen-11'-yl)-scopoletin, designated driportlandin (1) and a new abietane quinoid diterpene 16-hydroxy-abieta-8,12-diene-11,14-dione, named portlanquinol (2) together with lupeol, nepehinol, wrightial, formonetin and davidigenin were isolated and characterized from the me2co extract of whole dried plant of euphorbia portlandica. the structures of the new compounds were elucidated from spectral data includin ...200415503353
delphastus catalinae and coleomegilla maculata lengi (coleoptera: coccinellidae) as biological control agents of the greenhouse whitefly, trialeurodes vaporariorum (homoptera: aleyrodidae).predation efficacy and compatibility of the predatory lady beetles coleomegilla maculata lengi timberlake and delphastus catalinae (horn) against the greenhouse whitefly, trialeurodes vaporariorum (westwood) were studied in laboratory on glabrous fuchsia (fuchsia hybrida voss cv lena corolla) and pubescent poinsettia plants (euphorbia pulcherrima willd ex klotzch cv dark red annette hegg). on glabrous plants (fuchsia), fourth-instar and adults of c maculata were the most efficient, both against ...200415532680
the origin and radiation of macaronesian beetles breeding in euphorbia: the relative importance of multiple data partitions and population sampling.species-level phylogenies derived from many independent character sources and wide geographical sampling provide a powerful tool in assessing the importance of various factors associated with cladogenesis. in this study, we explore the relative importance of insular isolation and host plant switching in the diversification of a group of bark beetles (curculionidae: scolytinae) feeding and breeding in woody euphor biaspurges. all species in the genus aphanarthrumare each associated with only one ...200415545251
distribution of phytoplasmas in infected plants as revealed by real-time pcr and bioimaging.phytoplasmas are cell wall-less bacteria inhabiting the phloem and utilizing it for their spread. infected plants often show changes in growth pattern and a reduced crop yield. a quantitative real-time polymerase chain reaction (q-pcr) assay and a bioimaging method were developed to quantify and localize phytoplasmas in situ. according to the q-pcr assay, phytoplasmas accumulated disproportionately in source leaves of euphorbia pulcherrima and, to a lesser extent, in petioles of source leaves an ...200415553243
cytotoxicity of three new triazolo-pyrimidine derivatives against the plant trypanosomatid: phytomonas sp. isolated from euphorbia characias.there is no effective chemotherapy against diseases caused by phytomonas sp., a plant trypanosomatid responsible for economic losses in major crops. we tested three triazolo-pyrimidine complexes [two with pt(ii), and another with ru(iii)] against promastigotes of phytomonas sp. isolated from euphorbia characias. the incorporation of radiolabelled precursors, ultrastructural alterations and changes in the pattern of metabolite excretion were examined. different degrees of toxicity were found for ...200415558180
effects of two plant extracts on larval leafminer liriomyza trifolii (diptera: agromyzidae) in tomatoes.aqueous extracts from two plants, urginea maritima l. (liliaceae) and euphorbia myrsinites l. (euphorbiaceae), were tested for their insecticidal activity against the leafminer liriomyza trifolii (burgess) on infested tomato, lycopersicon esculentum mill., plants in the laboratory and field. two grams of plant material was extracted with 100 ml of water and then diluted 1:100, 1:50, and 1:25 with distilled water. diluted plant extract was either applied to the infested tomato leaves or by soil d ...200415568346
is endemic burkitt's lymphoma an alliance between three infections and a tumour promoter?malaria and epstein-barr virus (ebv), recognised cofactors for endemic burkitt's lymphoma, are ubiquitous within the lymphoma belt of africa, and, unless other cofactors are involved, the tumour should be much more common than it is. malaria and ebv alone cannot account for the occasional shifting foci and space-time case clusters of endemic burkitt's lymphoma. arboviruses and plant tumour promoters are other possible local cofactors that could explain such characteristics. the geographical and ...200415581545
toxicological effect and biochemical alterations induced by different fractions of euphorbia royleana latex in freshwater harmful vector snail lymnaea acuminata.laboratory evaluation was made to assess the molluscicidal activity of different fractions of euphorbia royleana (family- euphorbiaceae) latex obtained through sephadex gel column against freshwater snail lymnaea (radix) acuminata lamarack. this snail is the vector of liver fluke, fasciola hepatica linnaeus and fasciola gigantica cobbold, which causes endemic fascioliasis in cattle and livestock. the toxic effect of the different fractions was time dependent and fifth fraction obtained through b ...200415623235
ingenol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in melanoma cells.ingenol 3-angelate (pep005), one of the active ingredients in an extract from euphorbia peplus, was shown in preclinical studies to have activity against human melanoma xenografts in nude mice. in the present study, we have tested its ability to induce the apoptosis of melanoma cells in vitro in the absence or presence of tumor necrosis factor-related apoptosis inducing ligand (trail). the results showed that at relatively high concentrations (100 microg/ml), pep005 killed melanoma cells mainly ...200415634659
analysis of serpentinophytes from north-east of portugal for trace metal accumulation--relevance to the management of mine environment.in north-east of portugal, the serpentinized area is about 8000 ha with a characteristic geology and flora. the serpentine plant community and respective soils were analyzed to examine the trace metal budget in different tissues of the plants exhibiting resistance to trace metals. one hundred and thirty five plant species belonging to 39 families and respective soils have been analyzed for total co, cr, cu, fe, mn, ni, pb and zn. substantial amounts of ni, cr, co and mn were detected in plant ti ...200414675842
tocopherols, fatty acids and sterols in seeds of four sardinian wild euphorbia species.sardinian wild euphorbia pithyusa, e. semiperfoliata, e. dendroides and e. characias seed oils were analyzed for their fatty acids, unsaponifiable and tocopherol content. total tocopherol content showed a wide variability, ranging from 939 mg/kg in e. semiperfoliata seeds to its absence in e. characias. the results on tocopherol content were statistically correlated with both 1,1-diphenyl-2-picrylhydrazyl (dpph) radical scavenging test and the beta-carotene bleaching antioxidant test. all seeds ...200414693220
phytomonas iron superoxide dismutase: a possible molecular marker.we have isolated and biochemically characterized two iron superoxide dismutases activities (sodi and sodii) from a plant trypanosomatid isolated from euphorbia characias. the isoenzyme fesodii has immunogenic capacity, and the positivity of the anti-sodii serum persists to a dilution of 1/40,000, by western blot. in addition, western blot has been used to test the positivity of the anti-sodii serum against antigen fractions (sod) from 17 isolates belonging to the family trypanosomatidae and for ...200415109721
euphopubescenol and euphopubescene, two new jatrophane polyesters, and lathyrane-type diterpenes from euphorbia pubescens.the structures of euphopubescenol and euphopubescene, two new macrocyclic jatrophane diterpene polyesters, isolated from the whole dried plant of euphorbia pubescens, were established as 5alpha,8alpha,15beta-triacetoxy-3alpha-benzoyloxy -4alpha-hydroxy -9,14-dioxo-13beta h-jatropha-6(17),11 e-diene ( 1) and 3beta,7beta,8beta,9alpha,14alpha,15beta-hexaacetoxy-2beta h-jatropha-5 e,11 e-diene ( 2) by 1d- and 2d-nmr (cosy, hmqc, hmbc and noesy), ir, ei-ms and ei-fticr-ms. two known lathyrane derivat ...200415114502
characterization of the interaction of ingenol 3-angelate with protein kinase c.ingenol 3-angelate (i3a) is one of the active ingredients in euphorbia peplus, which has been used in traditional medicine. here, we report the initial characterization of i3a as a protein kinase c (pkc) ligand. i3a bound to pkc-alpha in the presence of phosphatidylserine with high affinity; however, under these assay conditions, little pkc isoform selectivity was observed. pkc isoforms did show different sensitivity and selectivity for down-regulation by i3a and phorbol 12-myristate 13-acetate ...200415126366
ocular injuries from plant sap of genera euphorbia and dieffenbachia.clinical findings in 3 cases of ocular injuries caused by the milky latex from euphorbia tirucalli and dieffenbachia sequine were reported. the initial symptoms of all patients were burning pain with subsequently blurred vision. visual acuity was reduced between 6/30 and 6/20. euphorbia sap caused punctate erosion, microbullae and descemet's folds; while dieffenbachia sap induced conjunctival chemosis and fine blue crystals in the stroma. ocular symptoms developed in 5 to 18 hours despite immedi ...200415146906
effect of cycloartanes on reversal of multidrug resistance and apoptosis induction on mouse lymphoma cells.the ability of fifteen cycloartanes, isolated from euphorbia species, to reverse multidrug resistance (mdr) and apoptosis induction in l5178y mouse lymphoma cells, including its multidrug-resistant subline, was studied by flow cytometry. reversion of mdr was investigated using a standard functional assay with rhodamine 123 as a fluorescent substrate analogue. for the evaluation of apoptosis, the cells were stained with fitc-labeled annexin v and propidium iodide. the majority of the compounds we ...200415161038
bioactive diterpenoids, a new jatrophane and two ent-abietanes, and other constituents from euphorbia pubescens.a new jatrophane diterpene, pubescenol (1), known ent-abietane lactones, helioscopinolide a (2) and b (3), and taraxerone, 24-methylenecycloartanol, and vanillin have been isolated from euphorbia pubescens. diterpenes 1-3 and previously described pubescene d (4) were shown to be moderate inhibitors of the growth of mcf-7, nci-h460, and sf-268 human tumor cell lines, whereas compounds 2 and 3 also exhibited significant antibacterial activity against staphylococcus aureus.200415165162
in vitro antiplasmodial activity of extracts and fractions from seven medicinal plants used in the democratic republic of congo.the in vitro antiplasmodial activity of seven etoh extracts and twenty fractions from the partition of the initial ethanolic extracts from seven african medicinal plants used in the democratic republic of congo (dr congo) for the treatment of malaria was evaluated. the most active etoh extracts (ic50 < 3 microg/ml) were those from cassia occidentalis leaves, euphorbia hirta whole plant, garcinia kola stem bark and phyllanthus niruri whole plant. their respective petroleum ether soluble fractions ...200415182900
structure and biogenesis of jolkinin, a highly oxygenated ellagitannin from euphorbia jolkinii.a new ellagitannin, jolkinin (2), was isolated from the fresh whole plant of euphorbia jolkinii, and its structure, including absolute configuration, was determined on the basis of spectroscopic and chemical evidence. a highly oxygenated acyl group with unique hexacyclic structure is attached to the 2,4-positions of 1-o-galloyl-3,6-(r)-hexahydroxydiphenoyl-beta-d-glucopyranose. the structural similarity to elaeocarpusin (4) suggests that jolkinin is produced by a condensation reaction between as ...200415217286
[repellent and antifeedant effect of secondary metabolites of non-host plants on plutella xylostella].based on the theory of co-evolution between plants and phytophagous insects, the repellent and antifeedant effect of secondary metabolites of non-host plants on diamondback moth(dbm) plutella xylostella was studied, aimed at finding out the oviposition repellents and antifeedants of insect pests. when the ethanol extracts(etho exts) of bauhinia variegata, eucalyptus tereticornis, euphorbia hirta, duranta repens, zanthoxylum bungeanum, magnolia grandiflora, and nicotiana tabacum were applied resp ...200415228000
structure-activity relationships for euphocharacins a-l, a new series of jatrophane diterpenes, as inhibitors of cancer cell p-glycoprotein.the mediterranean spurge euphorbia characias l. afforded twelve new diterpenes based on a jatrophane skeleton named euphocharacins a-l. their chemical structures were elucidated by extensive nuclear magnetic resonance and mass spectrometry methods. euphocharacins a-l were tested as inhibitors of the daunomycin-efflux activity of p-glycoprotein from cancer cells. the results were used to extend the structure-activity relationship established for this class of compounds, highlighting the positive ...200415254859
purification and characterization of two iron superoxide dismutases of phytomonas sp. isolated from euphorbia characias (plant trypanosomatids).two superoxide dismutases (sodi and sodii) have been purified by differential centrifugation, fractionation with ammonium sulphate followed by chromatographic separation (ionic exchange and affinity), from a plant trypanosomatid isolated from euphorbia characias, and then characterized for several biochemical properties. both enzymes were insensitive to cyanide but sensitive to hydrogen peroxide, properties characteristic of iron-containing superoxide dismutase. sodi had a molecular mass of appr ...200415267114
plants used for poison fishing in tropical africa.fishing with the aid of poisonous plants was formerly very common in africa. today this easy and simple method of fishing is forbidden but still practised in remote areas. the poisonous ingredients are pounded and thrown into a pool or dammed sections of a small river. after a time which varies according to conditions the fish begin to rise to the surface of the water and can readily be taken by hand. in general, the fish can be eaten without problems. 325 fish-poisoning plants, spread among 71 ...200415302524
the effect of medicinal plants of islamabad and murree region of pakistan on insulin secretion from ins-1 cells.in vitro testing of the extracts of medicinal plants collected from islamabad and the murree region on insulin secretagogue activity was carried out. dried ethanol extracts of all plants (zh1-zh19) were dissolved in ethanol and dmso, and tested at various concentrations (between 1 and 40 microg/ml) for insulin release from ins-1 cells in the presence of 5.5 mm glucose. glibenclamide was used as a control. promising insulin secretagogue activity in various plant extracts at 1, 10, 20 and 40 micro ...200414750205
jatrophane diterpenes as modulators of multidrug resistance. advances of structure-activity relationships and discovery of the potent lead pepluanin a.from the whole plant of euphorbia peplus l., five new diterpenes based on a jatrophane skeleton (pepluanins a-e, 1-5) were isolated, together with two known analogues (6 and 7), which served to divulge in detail the structure-activity relationships within this class of p-glycoprotein inhibitors. the results revealed the importance of substitutions on the medium-sized ring (carbons 8, 9, 14, and 15). in particular, the activity is collapsed by the presence of a free hydroxyl at c-8, while it incr ...200414761200
activity of euphorbia splendens var. hislopii n.e.b. (euphorbiaceae) latex against lymnaea columella (say, 1817) (pulmonata: lymnaeidae), intermediate host of fasciola hepatica, linnaeus, 1758 (trematoda: fasciolidae). 2: limited field-testing.the molluscicidal evaluation of euphorbia splendens var. hislopii (crown of thorns) against lymnaea columella snails, intermediate host of fasciola hepatica, in irrigation ditches of the pisciculture station at universidade federal rural do rio de janeiro, was studied under limited field conditions. an aqueous solution of the latex at 5 mg/l was tested in two irrigation ditches (experimental and control ditches), after initial sampling of the snail population present. twenty-four hours after app ...200414762529
rearranged jatrophane-type diterpenes from euphorbia species. evaluation of their effects on the reversal of multidrug resistance.the rearranged jatrophane-type diterpenes ( 1 - 3), isolated from the me (2)co extracts of euphorbia portlandica and euphorbia segetalis, were examined for their effects on multidrug resistance (mdr) in mouse lymphoma cells. compounds 2 and 3 revealed to be active with the latter being more active than the positive control verapamil, a known resistance modifier. the new compound 1, named portlandicine, was isolated from euphorbia portlandica and its structure characterised by high-field nmr spec ...200414765292
pubescenes, jatrophane diterpenes, from euphorbia pubescens, with multidrug resistance reversing activity on mouse lymphoma cells.the macrocyclic jatrophane diterpene polyesters, pubescenes a - d ( 1 - 4) were isolated from the whole dried plant of euphorbia pubescens, and evaluated for multidrug resistance (mdr) reversing activity on mouse lymphoma cells. all the compounds displayed very strong activity compared with the positive control verapamil. pubescene d ( 4) is a new compound, whose structure was established as 3beta,9alpha,-diacetoxy-7beta-benzoyloxy-15beta-hydroxy-14-oxo-2beta h-jatropha-5 e,12 e-diene by spectro ...200414765302
chemical constituents and energy content of some latex bearing plants.the latex bearing plants plumeria alba, calotropis procera, euphorbia nerrifolia, nerium indicum and mimusops elengi were evaluated as potential renewable sources of energy and chemicals. plant parts (leaf, stem, bark) and also whole plants were analyzed for elemental composition, oil, polyphenol, hydrocarbons, crude protein, alpha-cellulose, lignin and ash. the dry biomass yields were between 4.47 and 13.74 kg/plant. the carbon contents in whole plants varied from 38.5% to 44.9%, while hydrogen ...200414766154
self assembly of epicuticular waxes on living plant surfaces imaged by atomic force microscopy (afm).the cuticle of terrestrial vascular plants and some bryophytes is covered with a complex mixture of lipids, usually called epicuticular waxes. self-assembly processes of wax molecules lead to crystalline three-dimensional micro- and nanostructures that emerge from an underlying wax film. this paper presents the first afm study on wax regeneration on the surfaces of living plants and the very early stages of wax crystal formation at the molecular level. wax formation was analysed on the leaves of ...200414966216
a new tetracyclic triterpene from the latex of euphorbia nerifolia.a new tetracyclic triterpene 9,19-cyclolanost-22(22'), 24-diene-3beta-ol, named as nerifoliene (2) along with euphol (1) were isolated from the fresh latex of euphorbia nerifolia. their structures were elucidated on the basis of spectral (ir, 1h and 13c nmr, fab and ei mass) data.200414974615
two new flavonol glycosides from gymnema sylvestre and euphorbia ebracteolata.two new flavonol glycosides, namely kaempferol 3-o-beta-d-glucopyranosyl-(1-->4)-alpha-l-rhamnopyranosyl-(1-->6)-beta-d-galactopyranoside (1) and quercetin 3-o-6"-(3-hydroxyl-3-methylglutaryl)-beta-d-glucopyranoside (2), have been isolated from the aerial parts of gymnema sylvestre and euphorbia ebracteolata, respectively. their structures were determined on the basis of chemical and spectroscopic methods.200414980834
two novel steroids from euphorbia officinarum latex.two novel steroids, 3beta,7alpha-dihydroxy-4alpha,14alpha-dimethyl-5alpha-cholest-8-en-11-one (2) and 3beta,7beta-dihydroxy-4alpha,14alpha-dimethyl-5alpha-cholest-8-en-11-one (3) were isolated from the latex of euphorbia officinarum. their structures were established on the basis of nmr and ms studies.200414984093
molecular determinants of vanilloid sensitivity in trpv1.vanilloid receptor 1 (trpv1), a membrane-associated cation channel, is activated by the pungent vanilloid from chili peppers, capsaicin, and the ultra potent vanilloid from euphorbia resinifera, resiniferatoxin (rtx), as well as by physical stimuli (heat and protons) and proposed endogenous ligands (anandamide, n-arachidonyldopamine, n-oleoyldopamine, and products of lipoxygenase). only limited information is available in trpv1 on the residues that contribute to vanilloid activation. interesting ...200414996838
putranjivain a from euphorbia jolkini inhibits both virus entry and late stage replication of herpes simplex virus type 2 in vitro.to investigate the in vitro antiviral properties of putranjivain a, isolated from the whole plant of euphorbia jolkini bioss (euphorbiaceae).200414998984
chemical constituents of euphorbia marschalliana boiss.acetone extract of aerial parts of euphorbia marschalliana collected from iran has been subjected to different chromatography techniques for fractionation and purification. the stereo-structures of the myrsinol esters 15-o-acetyl-3-o-propionyl-5-o-butanoyl-7-o-nicotinoylmyrsinol (1) and 15-o-acetyl-3,5-o-dibutanoyl-7-o-nicotinoylmyrsinol (2) have been probed using roesy spectroscopy and modified for the stereochemistry at c-6, c-12 and c-13. beta-sitosterol (3), 29-norcycloart-5-ene (4), 5,8-lan ...200415018044
abiotic stress alters transcript profiles and activity of glutathione s-transferase, glutathione peroxidase, and glutathione reductase in euphorbia esula.glutathione s-transferase (gst), glutathione peroxidase (gpx), and glutathione reductase (gr) are enzymes that utilize glutathione to play an important role in plant defense mechanisms. in leafy spurge (euphorbia esula l.), transcript and activity profiles for these enzymes are differentially influenced in tissue exposed to xenobiotic (diclofop-methyl) and environmental stress (cold and drought). five different eegst cdna (including phi, tau, theta, and zeta class gsts), one eegpx cdna, and one ...200415032839
toxicity of euphorbia canariensis latex to some developmental stages of drosophila melanogaster (diptera: drosophilidae). 200415058653
phylogeny of a macaronesian radiation: host-plant use and possible cryptic speciation in liparthrum bark beetles.the macaronesian islands are well known for their unique endemic floras of woody plants. many of these unusual plant groups provide important novel resources for bark and wood boring beetles which breed in dead or moribund parts of their host plants. the bark beetle genus liparthrum exploits a wide range of unusual host plants and has its highest proportion of species living on the macaronesian islands. we used dna sequences of the mitochondrial cytochrome oxidase i gene and the nuclear elongati ...200415062794
antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death.options for skin cancer treatment currently include surgery, radiotherapy, topical chemotherapy, cryosurgery, curettage, and electrodessication. although effective, surgery is costly and unsuitable for certain patients. radiotherapy can leave a poor cosmetic effect, and current chemotherapy is limited by low cure rates and extended treatment schedules. here, we describe the preclinical activity of a novel topical chemotherapeutic agent for the treatment of skin cancer, 3-ingenyl angelate (pep005 ...200415087400
asthma induced by latex from 'christmas flower' (euphorbia pulcherrima). 200415355476
structural characterization of rubber from jackfruit and euphorbia as a model of natural rubber.a structural study of low molecular weight rubbers from jackfruit (artocarpus heterophyllus) and painted spurge (euphorbia heterophylla) was carried out as model compounds of natural rubber from hevea brasiliensis. the rubber content of latex from jackfruit was 0.4-0.7%, which is very low compared with that of 30-35% in the latex from hevea tree. the rubber from jackfruit latex was low molecular weight with narrow unimodal molecular weight distribution (mwd), whereas that obtained from e. hetero ...200415360318
activity of macrocyclic jatrophane diterpenes from euphorbia kansui in a trka fibroblast survival assay.three new macrocyclic diterpenes, kansuinins f (1), g (2), and h (3), together with four known jatrophane diterpenes, kansuinins d (4), e (5), and a (6) and 3beta,5alpha,7beta,15beta-tetraacetoxy-9alpha-nicotinoyloxyjatropha-6(17)-11e-dien-14-one, were isolated from the roots of euphorbia kansui. compounds 1 and 2 were assigned as 6(17)-en-11,12-epoxy-14-one-type jatrophane diterpenes, and compound 3 as a 6(17)-en-11,14-epoxy-12-one jatrophane diterpene. the structures of compounds 1-3 and the r ...200415387657
acute toxicity of euphorbia kamerunica on oreochromis niloticus.a series of static short-term bioassays was conducted to assess the acute toxicity of the plant euphorbia kamerunica on the fingerlings of oreochromis niloticus. the 96-h lc(50) was computed using two methods: probit analysis and the arithmetic graphic method. the overall mean value of 0.023 +/- 0.002 g/l was obtained. aquatic invertebrates are generally much more sensitive than fish species. poisoning of streams with this plant to capture fish may therefore have ecological consequences, as nont ...200415978298
plant medicines of indian origin for wound healing activity: a review.research on wound healing drugs is a developing area in modern biomedical sciences. scientists who are trying to develop newer drugs from natural resources are looking toward the ayurveda, the indian traditional system of medicine. several drugs of plant, mineral, and animal origin are described in the ayurveda for their wound healing properties under the term vranaropaka. most of these drugs are derived from plant origin. some of these plants have been screened scientifically for the evaluation ...200315866825
lipophylic compounds from euphorbia peplis l.--a halophytic plant from the bulgarian black sea coast.the chemical composition of the lipophylic fraction from the halophytic plant euphorbia peplis l. was investigated. compared to other terrestrial higher plants an increase of triacylglycerols and especially of glycolipids was observed. the main phospholipid was phosphatidyl choline, followed by almost equal concentrations of phosphatidyl ethanolamine and phosphatidyl glycerol. a relatively high concentration of phosphatidic acids (6.5% of the total phospholipids) was found. the main sterol appea ...200314713150
new bioactive diterpene polyesters from euphorbia decipiens.a reinvestigation with a modified extraction procedure of euphorbia decipiens resulted in the isolation and structure elucidation of three new myrsinane-type diterpene esters (1-3). the structures of compounds 1-3 were elucidated by spectroscopic data interpretation. compound 1 showed inhibitory activity against prolyl endopeptidase (pep), whereas compound 2 exhibited dna-damaging activity in a mutant yeast bioassay.200314510601
evaluation of the antiviral and antimicrobial activities of triterpenes isolated from euphorbia segetalis.a phytochemical reinvestigation of the whole plant of euphorbia segetalis yielded five tetracyclic triterpenes: 3beta-hydroxy-cycloart-25-en-24-one (1), cycloart-25-ene-3beta,24-diol (2), cycloart-23-ene-3beta,25-diol (3), lanosta-7,9(11),24-trien-3beta-ol (4) and lanosta-7,9(11),24(31)-trien-3beta-ol (5). beta-acetoxy-cycloart-25-en-24-one (1a) and glutinol (6), lupenone (7), dammaranodienol (9), cycloartenol acetate (10), 24-methylenecycloartanol acetate (11) and beta-sitosterol (12), isolated ...200314526920
absence of tumor promoting activity of euphorbia milii latex on the mouse back skin.euphorbia milii (euphorbiaceae) is a decorative plant used in gardens and living fences. in china, it has also been employed in herbal remedies for hepatitis and abdominal edema. since e. milii latex--lyophilized or in natura--proved to be a potent plant molluscicide, its toxicity to non-target organisms has been comprehensively studied. concerns on a possible tumor promoting activity have discouraged its use as a locally-available alternative molluscicide in schistosomiasis control programs. tw ...200314581170
modified jatrophane diterpenes as modulators of multidrug resistance from euphorbia dendroides l.the new diterpenoids terracinolides j-l (1-3), 13alpha-oh terracinolide f (8), abeodendroidin f (11) and epiabeodendroidin f (12) have been identified from euphorbia dendroides l. the new compounds and six co-occurring known terracinolides were tested as inhibitors of the drug-efflux activity of p-glycoprotein from cancer cells. the results were used to extend the structure-activity relationships established for this class of compounds highlighting the relevance of substitution at positions 2, 3 ...200314604686
morphometric and histopathological studies on the effects of some chromatographic fractions of phyllanthus amarus and euphorbia hirta on the male reproductive organs of rats.the aqueous crude extracts of p. amarus and e. hirta were administered to thirty eight-week old sexually mature male albino to determine the effects of these extracts on the male reproductive organs of these animals. the results from this study revealed that the aqueous crude extracts of p. amarus and e. hirta caused varying degrees of testicular degeneration as well as reduction in the mean seminiferous tubular diameter (std) in the treated rats. it thus shows that the aqueous crude extracts of ...200314610373
new cerebrosides from euphorbia peplis l.: antimicrobial activity evaluation.the less polar fraction of the methanolic extract from the plant euphorbia peplis l. exhibited interesting antifungal and antitubercular activity. a complex mixture of four glucocerebrosides was responsible for this activity. two new cerebrosides were isolated for the first time from euphorbiaceae, 4 was assigned as 1-o-(beta-d-glucopyranosyl)-(2s,3s,4e,8e)-2n-[(2'r)-2'-hydroxy-hexadecanoyl]-4 (e), 8 (e)-octadecadiene-1,3-diol and 3 as the 1-o-(beta-d-glucopyranosyl)-(2s,3s,4r,8z)-2n-[(2'r)-2'-h ...200314643323
efficacy of euphorbia splendens and leonotis nepetaefolia on aflatoxin producing fungi aspergillus flavus and aspergillus parasiticus.efficacy of three different concentrations (5, 10 and 15 mg/ml) of dry flower powder of e. splendens and l. nepetaefolia was tested on the growth of aflatoxin-producing toxigenic strains of fungi a. flavus (ncbt 101) and a. parasiticus (ncbt 128) in sabouraud dextrose agar medium (sda). maximum (75%) inhibition of growth of a. flavus was seen at 15 mg/ml concentration of e. splendens flower dry powder, while a. parasiticus showed 50% inhibition of growth at 10 and 15 mg/ml concentrations. total ...200315320507
cross resistance to als-inhibiting herbicides in euphorbia heterophylla l. biotypes resistant to imazethapyr.the effect of weeds on the diminution of agricultural production is considered to be between 30 and 50%. imazethapyr is a herbicide which acts on the enzyme als, the first common enzyme in the biosynthetic pathway of valine, leucine and isoleucine. euphorbia heterophylla is a common species in soybean fields in brazil and different populations resistant to herbicides of the sulfonylurea and imidazolinone groups are currently being reported. the objectives of this work were: to determine the resi ...200315149128
molluscicidal and in-vitro schistosomicidal activities of the latex and some extracts of some plants belonging to euphorbiacea.plant molluscicicdes proved to be good means for controlling fresh water snails of schistosomiasis. the molluscicidal activities of the natural and lyophilized latex extracts of euphorbia royleana and e. mouritanica and acetonitril and chloroform extracts of jatropha carcus were investigated against biomphalaria alexandrina the intermediate hosts for s. mansoni. the lyophilized latex extract of e. royleana showed the highest toxicity against snails with lc90 value of 11 ppm. while the natural la ...200314708864
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