Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| methicillin resistant staphylococcus aureus sacroiliac joint septic arthritis in an adult patient treated with daptomycin. | sacroiliac joint septic arthritis is a rare disease entity representing 1-2% of all cases of septic arthritis. establishment of the diagnosis is often challenging given the non-specific presenting features and the potential cross-over with other pathologies. we report the case of a 50 year old gentleman who suffers with psoriasis and presented with sacroiliac joint septic arthritis complicated by methicillin resistant staphylococcus aureus (mrsa) bacteraemia and an iliopsoas abscess. this was su ... | 2017 | 28540151 |
| improved annotations of 23 differentially expressed hypothetical proteins in methicillin resistant s.aureus. | antibiotic resistant staphylococcus aureus is a major public health concern effecting millions of people annually. medical science has documented completely untreatable s. aureus infections. these strains are appearing in the community with increasing frequency. new diagnostic and therapeutic options are needed to combat this deadly infection. interestingly, around 50% of the proteins in s. aureus are annotated as hypothetical. methods to select hypothetical proteins related to antibiotic resist ... | 2017 | 28539731 |
| purpuric drug eruptions caused by epidermal growth factor receptor inhibitors for non-small cell lung cancer: a clinicopathologic study of 32 cases. | purpuric skin lesions have only rarely been reported in patients receiving epidermal growth factor receptor inhibitors. however, their clinical and histopathologic presentations have varied considerably. | 2017 | 28538945 |
| characteristics of and risk factors for severe neurological deficit in patients with pyogenic vertebral osteomyelitis: a case-control study. | severe neurological deficit (snd) is a rare but major complication of pyogenic vertebral osteomyelitis (pvo). we aimed to determine the risk factors and the variables associated with clinical improvement for snd during pvo.this case-control study included patients without pvo-associated snd enrolled in a prospective randomized antibiotic duration study, and patients with pvo-associated snd managed in 8 french referral centers. risk factors for snd were determined by logistic regression.ninety-se ... | 2017 | 28538361 |
| 5-benzylidene-4-oxazolidinones potently inhibit biofilm formation in methicillin-resistant staphylococcus aureus. | investigation into the biological function of 5-benzylidene-4-oxazolidinones revealed dose-dependent inhibition of biofilm formation in methicillin-resistant s. aureus (mrsa). this structurally unusual class of small molecules inhibit up to 89% of biofilm formation with ic50 values as low as 0.78 μm, and disperse pre-formed biofilms with ic50 values as low as 4.7 μm. together, these results suggest that 4-oxazolidinones represent new chemotypes to enable the study of bacterial biofilms with smal ... | 2017 | 28537316 |
| ccpa affects infectivity of staphylococcus aureus in a hyperglycemic environment. | many bacteria regulate the expression of virulence factors via carbon catabolite responsive elements. in gram-positive bacteria, the predominant mediator of carbon catabolite repression is the catabolite control protein a (ccpa). hyperglycemia is a widespread disorder that predisposes individuals to an array of symptoms and an increased risk of infections. in hyperglycemic individuals, the bacterium staphylococcus aureus causes serious, life-threatening infections. the importance of ccpa in regu ... | 2017 | 28536677 |
| economic evaluation of infection control activities. | healthcare-associated infections by drug-resistant bacteria affect a patient's prognosis. infection control activities at medical institutions in japan are increasingly focused on the threat from these bacteria. | 2017 | 28535969 |
| a review of eight cases of cavernous sinus thrombosis secondary to sphenoid sinusitis, including a12-year-old girl at the present department. | cavernous sinus thrombosis (cst) is a severe disease which can result from infection of any of the tissues drained by the cavernous sinus. we here review eight cases, including a 12-year-old girl, all secondary to sphenoid sinusitis. the clinical manifestations, laboratory data, imaging findings, pathogens, medications, surgical treatment and clinical outcomes were analyzed. all eight patients had headache and five of them fever. all cases were associated with one or more ophthalmic symptoms. in ... | 2017 | 28535728 |
| diabetes increases the risk of disease and death due to staphylococcus aureus bacteremia. a matched case-control and cohort study. | this study investigated the effect and influence of diabetes severity on susceptibility and 30-day mortality of staphylococcus aureus bacteremia (sab). | 2017 | 28535702 |
| effect of cephalexin plus trimethoprim-sulfamethoxazole vs cephalexin alone on clinical cure of uncomplicated cellulitis: a randomized clinical trial. | emergency department visits for skin infections in the united states have increased with the emergence of methicillin-resistant staphylococcus aureus (mrsa). for cellulitis without purulent drainage, β-hemolytic streptococci are presumed to be the predominant pathogens. it is unknown if antimicrobial regimens possessing in vitro mrsa activity provide improved outcomes compared with treatments lacking mrsa activity. | 2017 | 28535235 |
| chlorhexidine and silver sulfadiazine coating on central venous catheters is not sufficient for protection against catheter-related infection: simulation-based laboratory research with clinical validation. | objective the efficacy of chlorhexidine- and silver sulfadiazine-coated central venous catheters (css-cvc) against catheter-related infection remains controversial. we hypothesized that the loss of silver nanoparticles may reduce the antibacterial efficacy of css-cvcs and that this loss could be due to the frictional force between the surface of the cvc and the bloodstream. the objective of this study was to investigate whether the antimicrobial effect of css-cvcs decreases with increasing expos ... | 2017 | 28534703 |
| hyaluronic acid-templated ag nanoparticles/graphene oxide composites for synergistic therapy of bacteria infection. | developing methods of decreasing the harm to cell and increasing the antibacterial efficiency is becoming a potential topic of medical treatments. we demonstrated a hyaluronidase-triggered photothermal platform for killing bacteria based on silver nanoparticles (agnps) and graphene oxide (go). the property of the hyaluronidase (haase)-triggered release provided excellent antibacterial activity against staphylococcus aureus. upon illumination of nir light, the go-based nanomaterials locally raise ... | 2017 | 28534395 |
| [acute haematogenous osteomyelitis in children : diagnostic algorithm and treatment strategies]. | acute haematogenous osteomyelitis (aho) in children is a severe condition. a delay in diagnosis and insufficient treatment may result in deformities, chronicity and sepsis. therefore a structured diagnostic workup has to be followed in order to diagnose or rule out osteomyelitis. to identify the causative agent for targeted antibiotic treatment, a bone biopsy or puncture should be performed. however, approximately 25% of cases are culture-negative even after biopsy. the knowledge of the typical ... | 2017 | 28534215 |
| molecular characterisation of methicillin-resistant staphylococcus aureus (mrsa) isolated at a large referral hospital in zambia. | methicillin-resistant staphylococcus aureus (mrsa) is globally recognized as an important public health problem. whereas comprehensive molecular typing data of mrsa strains is available, particularly in europe, north america and australia, similar information is very limited in sub-saharan africa including zambia. | 2017 | 28533831 |
| risk factors for 30-day mortality in patients with methicillin-resistant staphylococcus aureus bloodstream infections. | methicillin-resistant staphylococcus aureus (mrsa) blood stream infections (bsi) are a major health care problem accounting for a large percentage of nosocomial infections. the aim of this study was to identify risk factors associated with 30-day mortality in patients with mrsa bsi. | 2017 | 28533166 |
| ehs matrix incubated in media containing penicillin retains sufficient concentrations of antibiotic to inhibit growth of susceptible microorganisms. | in studying the interaction between bacteria and host cells in vitro, the latter are frequently cultured on commercially available biotic matrices such as matrigel® or geltrex®. to avoid contamination, host cells are commonly grown in the presence of antibiotics. however, we present here the finding that cell culture on such a matrix in the presence of antibiotics interferes with the outcome of subsequent infection experiments by virtue of diminished bacterial survival. by comparing outcomes for ... | 2017 | 28533107 |
| immune response of staphylococcus aureus strains in a mouse mastitis model is linked to adaptive capacity and genotypic profiles. | staphylococcus aureus is one of the most frequently isolated major pathogens from intramammary infections (imi) worldwide. the mechanisms by which s. aureus imi are established and maintained in dairy cows involve both bacterial escape strategies and modulation of the host immune response. moreover, it was shown that different s. aureus strains have varying effects on the immune response. the aim of this study was to investigate the immune response in a mouse mastitis model of two s. aureus stra ... | 2017 | 28532808 |
| the il-33/st2 axis is crucial in type 2 airway responses induced by staphylococcus aureus-derived serine protease-like protein d. | chronic airway inflammatory diseases, such as chronic rhinosinusitis with nasal polyps and asthma, show increased nasal staphylococcus aureus colonization. staphylococcus aureus-derived serine protease-like protein (spl) d and other closely related proteases secreted by s aureus have recently been identified as inducers of allergic asthma in human subjects and mice, but their mechanism of action is largely unknown. | 2017 | 28532656 |
| clinical outcomes of linezolid and vancomycin in patients with nosocomial pneumonia caused by methicillin-resistant staphylococcus aureus stratified by baseline renal function: a retrospective, cohort analysis. | the primary objective of this study is to assess whether baseline renal function impacts treatment outcomes of linezolid and vancomycin (with a dose-optimized regimen) for methicillin-resistant staphylococcus aureus (mrsa) pneumonia. | 2017 | 28532398 |
| erratum to: the holliday junction resolvase recu is required for chromosome segregation and dna damage repair in staphylococcus aureus. | 2017 | 28532385 | |
| ultra-small silver nanoparticles induced ros activated toll-pathway against staphylococcus aureus disease in silkworm model. | the present study investigated the therapeutic action of flavonoids loaded silver nanoparticles (flv-ag nps) on a silkworm, bombyx mori l., larvae infected by the s. aureus, where an in vivo model system was used. flv-ag nps were synthesized using a ricinus communis l. leaf extracted flavonoid mixture in various concentrations. the reduction reaction was performed under a simple sunlight exposure condition. in the reduction process, quercetin and kaempferol loadings were also found. they were co ... | 2017 | 28532120 |
| the controlled drug release by ph-sensitive molecularly imprinted nanospheres for enhanced antibacterial activity. | in this study, we prepared ph-sensitive hybrid nanospheres through the implementation of a facile molecularly imprinted polymer (mip) technique combined with a uv-initiated precipitation polymerization method using vancomycin (va) for the templates. during the course of this investigation, both 2-hydroxyethyl methacrylate (hema) and 2-(diethylamino) ethyl methacrylate (deaema) were utilized as the functional monomers, while ethylene glycol dimethacrylate (egdma) was used as a cross-linker. the o ... | 2017 | 28532100 |
| electrophoretic deposition of organic/inorganic composite coatings containing zno nanoparticles exhibiting antibacterial properties. | to address one of the serious problems associated with permanent implants, namely bacterial infections, novel organic/inorganic coatings containing zinc oxide nanoparticles (nzno) are proposed. coatings were obtained by electrophoretic deposition (epd) on stainless steel 316l. different deposition conditions namely: deposition times in the range 60-300s and applied voltage in the range 5-30v as well as developing a layered coating approach were studied. antibacterial tests against gram-positive ... | 2017 | 28532093 |
| controlled release of moxifloxacin from intraocular lenses modified by ar plasma-assisted grafting with amps or sbma: an in vitro study. | intraocular lenses (iols) present an alternative for extended, local drug delivery in the prevention of post-operative acute endophthalmitis. in the present work, we modified the surface of a hydrophilic acrylic material, used for manufacturing of iols, through plasma-assisted grafting copolymerization of 2-acrylamido-2-methylpropane sulfonic acid (amps) or [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)ammonium hydroxide (sbma), with the aim of achieving a controlled and effective drug relea ... | 2017 | 28531880 |
| surface-attached molecules control staphylococcus aureus quorum sensing and biofilm development. | bacteria use a process called quorum sensing to communicate and orchestrate collective behaviours, including virulence factor secretion and biofilm formation. quorum sensing relies on the production, release, accumulation and population-wide detection of signal molecules called autoinducers. here, we develop concepts to coat surfaces with quorum-sensing-manipulation molecules as a method to control collective behaviours. we probe this strategy using staphylococcus aureus. pro- and anti-quorum-se ... | 2017 | 28530651 |
| detection of prosthetic joint infection based on magnetically assisted surface enhanced raman spectroscopy. | accurate and rapid diagnosis of prosthetic joint infection (pji) is vital for rational and effective therapeutic management of this condition. several diagnostic strategies have been developed for discriminating between infected and noninfected cases. however, none of them can reliably diagnose the whole spectrum of clinical presentations of pji. here, we report a new method for pji detection based on magnetically assisted surface enhanced raman spectroscopy (ma-sers) using streptavidin-modified ... | 2017 | 28530395 |
| staphylococcus aureus manipulates innate immunity through own and host-expressed proteases. | neutrophils, complement system and skin collectively represent the main elements of the innate immune system, the first line of defense of the host against many common microorganisms. bacterial pathogens have evolved strategies to counteract all these defense activities. specifically, staphylococcus aureus, a major human pathogen, secretes a variety of immune evasion molecules including proteases, which cleave components of the innate immune system or disrupt the integrity of extracellular matri ... | 2017 | 28529927 |
| a novel esat-6 secretion system-secreted protein esxx of community-associated staphylococcus aureus lineage st398 contributes to immune evasion and virulence. | the esat-6 secretion system (ess) has been reported to contribute to the virulence and pathogenicity of several staphylococcus aureus strains such as usa300 and newman. however, the role of the ess in community-associated s. aureus (ca-sa) lineage st398 in china is not well understood. by comparing the ess locus of st398 with the published s. aureus sequence in the ncbi database, we found one gene in the ess locus encoding a novel wxg superfamily protein that is highly conserved only in st398. l ... | 2017 | 28529509 |
| effect of rocket (eruca sativa) extract on mrsa growth and proteome: metabolic adjustments in plant-based media. | the emergence of methicillin-resistant staphylococcus aureus (mrsa) in food has provoked a great concern about the presence of mrsa in associated foodstuff. although mrsa is often detected in various retailed meat products, it seems that food handlers are more strongly associated with this type of food contamination. thus, it can be easily postulated that any food could be contaminated with this pathogen in an industrial environment or in household and cause food poisoning. to this direction, th ... | 2017 | 28529502 |
| pancreatic abscess in a cat due to staphylococcus aureus infection. | a 16-year-old spayed female american shorthair cat was presented with lethargy, anorexia, and wamble. physical and blood examination did not reveal any remarkable findings. abdominal ultrasonography identified the presence of a localized anechoic structure with a thick wall in contact with the small intestine and adjacent to the liver. ultrasound-guided fine-needle aspiration of the structure revealed fluid containing numerous cocci and neutrophils. two days after antibiotic treatment, explorato ... | 2017 | 28529270 |
| continued expansion of usa300-like methicillin-resistant staphylococcus aureus (mrsa) among hospitalized patients in the united states. | we characterized spa types, sccmec types, and antimicrobial resistance patterns of 516 methicillin-resistant staphylococcus aureus (mrsa) isolates, collected between 2011 and 2014 from nares and blood cultures of united states patients. among nares isolates, 45 spa types were observed; 29.9% were t002/sccmec ii and 30.9% were t008/sccmec iv. among blood isolates, 40 spa types were identified; 24.4% were t002/sccmec ii and 39.9% were type t008/sccmec iv. compared to data from our 2009-2010 survey ... | 2017 | 28529090 |
| staphylococcus aureus lipoteichoic acid inhibits keratinocyte differentiation through a p63-mediated pathway. | 2017 | 28528912 | |
| mertk does not mediate phagocytosis of staphylococcus aureus but attenuates inflammation induced by staphylococcal lipoteichoic acid through blocking nf-κb activation. | mer receptor tyrosine kinase (mertk) expressed in macrophages is essential for phagocytosis of apoptotic cells. here, we investigate whether mertk is involved in the phagocytosis of staphylococcus aureus (s. aureus) and regulation of staphylococcal lipoteichoic acid (lta)-induced inflammatory response in macrophages. we found that stimulating raw264.7 macrophages with s. aureus activated multiple signaling pathways including toll-like receptor 2 (tlr2), scavenger receptor a (sr-a), and mertk. me ... | 2017 | 28528507 |
| dna carryover in milk samples from routine milk recording used for pcr-based diagnosis of bovine staphylococcus aureus mastitis. | real-time pcr techniques are increasingly used to detect udder pathogens from milk samples collected non-aseptically at routine milk recording. the objectives of this study were (1) to estimate the statistical associations between cycle threshold (ct) values for staphylococcus aureus in non-aseptically collected composite samples taken at routine milk recording from cows milked consecutively with the same milking unit and milk meter; and (2) to formulate practical and plausible guidelines for un ... | 2017 | 28527807 |
| improving the pharmacokinetics and tissue distribution of pyrinezolid by self-assembled polymeric micelles. | antibiotic-resistance by bacteria is a growing global concern within the healthcare field, and it has provided an impetus for continued antimicrobial development. pyrinezolid (pz), a novel oxazolidinone compound, can effectively inhibit most gram-positive bacteria, including methicillin-resistant staphylococcus aureus (mrsa) and vancomycin-resistant enterococci (vre). though pz is a promising antimicrobial candidate, the druggability of pz is limited by its poor water solubility. therefore, the ... | 2017 | 28527358 |
| zinc resistance within swine-associated methicillin-resistant staphylococcus aureus isolates in the united states is associated with multilocus sequence type lineage. | zinc resistance in livestock-associated methicillin-resistant staphylococcus aureus (la-mrsa) sequence type 398 (st398) is primarily mediated by the czrc gene colocated with the meca gene, encoding methicillin resistance, within the type v staphylococcal cassette chromosome mec (sccmec) element. because czrc and meca are located within the same mobile genetic element, it has been suggested that the use of zinc in feed as an antidiarrheal agent has the potential to contribute to the emergence and ... | 2017 | 28526788 |
| total joint replacement for neglected posterior knee dislocation following septic arthritis after arthroscopy. | this report presents the first case of a knee dislocation following septic arthritis after arthroscopy. a 65-year-old woman had an arthroscopy with irrigation and debridement (i&d) of the joint and microfracture for the chondral lesions. she had complaints of postarthroscopic infection but non-steroidal anti-inflammatory medication and local ice compression was recommended. she revisited her physician twice and at the last visit she had a large purulent effusion in her knee. the gram stain of th ... | 2017 | 28526569 |
| staphylococcus aureus colonization is associated with increased inhaled corticosteroid requirements in patients with atopic dermatitis and asthma. | 2017 | 28526276 | |
| environmental contamination with staphylococcus aureus at a large, midwestern university campus. | staphylococcus aureus can cause minor to severe life-threatening infections. the changing epidemiology of s. aureus is of public health concern due to the emergence of multi-drug resistant (mdr) strains. environmental surfaces play a crucial role in the transmission of s. aureus. the objective of this study was to examine environmental contamination and molecular characteristics of s. aureus in health professional-associated (hpa) and non-health professional-associated (nhpa) buildings at a larg ... | 2017 | 28525941 |
| two are better than one: dual targeting of riboswitches by metabolite analogs. | in this issue of cell chemical biology, wang et al. (2017) examine the effect of the novel synthetic molecule ribocil-c and the natural compound roseoflavin in gram-positive pathogens. in methicillin-resistant staphylococcus aureus (mrsa), ribocil-c and roseoflavin target two autonomous riboswitches simultaneously, thereby inhibiting de novo synthesis and uptake of riboflavin. | 2017 | 28525764 |
| molecular characterization and detection of enterotoxins, methicillin resistance genes and antimicrobial resistance of staphylococcus aureus from fish and ground beef. | a total of 120 samples including 40 freshwaterfish(oncorhynchus mykiss), 40 seawater fish (sparus aurata) and 40 ground beef samples were examined for the presence of staphylococcus aureus. the isolates were identified using biochemical tests and a pcr for the species-specific fragment (sa442) and thermonuclease gene (nuca). the presence of staphylococcal enterotoxin genes (sea, seb, sec, sed and see), toxin genes (eta, etb, tsst), methicillin resistance gene (meca) and some phenotypic virulence ... | 2017 | 28525337 |
| epidemiology of intramammary infections with staphylococcus aureus and mastitis streptococci in a dairy cattle herd with a history of recurrent clinical mastitis. | the aim of the present work was to examine a dairy herd with an anamnesis of recurrent clinical mastitis and decreased milk production. a total of 239 individual cow milk samples originating from asymptomatic cows were collected at four-month intervals and examined mainly for the presence of staphylococcus aureus and mastitis streptococci using standard cultivation methods. in total, 29.7% and 9.2% samples were positive for s. aureus and mastitis streptococci, respectively. unlike for mastitis s ... | 2017 | 28525325 |
| polydatin reduces staphylococcus aureus lipoteichoic acid-induced injury by attenuating reactive oxygen species generation and tlr2-nfκb signalling. | staphylococcus aureus (s. aureus) causes severe inflammation in various infectious diseases, leading to high mortality. the clinical application of antibiotics has gained a significant curative effect. however, it has led to the emergence of various resistant bacteria. therefore, in this study, we investigated the protective effect of polydatin (pd), a traditional chinese medicine extract, on s. aureus lipoteichoic acid (lta)-induced injury in vitro and in vivo. first, a significant improvement ... | 2017 | 28524642 |
| in vitro ability of mastitis causing pathogens to form biofilms. | this research communication describes the study of in vitro biofilm formation of mastitis causing pathogens. biofilms are communities of bacteria that are attached to a surface and to each other and are embedded in a self-produced matrix of extracellular polymeric substances. biofilm formation is an important virulence factor that may result in recurrent or persistent udder infections and treatment failure through increased resistance to antibiotics and protection against host defences. in the p ... | 2017 | 28524019 |
| humanized mouse models of staphylococcus aureus infection. | staphylococcus aureus is a successful human pathogen that has adapted itself in response to selection pressure by the human immune system. a commensal of the human skin and nose, it is a leading cause of several conditions: skin and soft tissue infection, pneumonia, septicemia, peritonitis, bacteremia, and endocarditis. mice have been used extensively in all these conditions to identify virulence factors and host components important for pathogenesis. although significant effort has gone toward ... | 2017 | 28523002 |
| molecular characterization of community acquired staphylococcus aureus bacteremia in young children in southern mozambique, 2001-2009. | background: the emergence of community-acquired staphylococcus aureus infections is increasingly recognized as life threating problem worldwide. in manhiça district, southern mozambique, s. aureus is the leading cause of community-acquired bacteremia in neonates. methods: eighty-four s. aureus isolates from children less than 5 years admitted to manhiça district hospital from 2001 to 2009 were randomly selected and genetically characterized by dna microarray and spa typing. antimicrobial suscept ... | 2017 | 28522992 |
| crispr/dcas9-mediated inhibition of gene expression in staphylococcus aureus. | the understanding of the genetic mechanism of staphylococcus aureus requires efficient tools, however, genetic manipulation in s. aureus is always laborious and time-consuming. here we proposed a novel crispr/dcas9 interference method for the rapid knockdown of target genes. furthermore, multiple genes can be repressed simultaneously by using this method. | 2017 | 28522389 |
| m2 macrophage is the predominant phenotype in airways inflammatory lesions in patients with granulomatosis with polyangiitis. | macrophages may present two distinct phenotypes indicated as m1 and m2 under different stimuli. m1 and m2 macrophages have divergent functions that range from enhancement of inflammation for m1 to tissue repair and remodeling for m2 macrophages. the objective of this study was to evaluate the distribution of m1 and m2 macrophage phenotypes in biopsies from the airways of patients with active granulomatosis with polyangiitis (gpa) and to analyze their associations with t and b cells in those biop ... | 2017 | 28521792 |
| effects of adaptation to carvacrol on staphylococcus aureus in the planktonic and biofilm phases. | the effect of exposure to sub-minimum inhibitory concentrations of carvacrol, for either 3-10 days, on direct (carvacrol) or cross-protection (cinnamaldehyde, eugenol, antibiotics) and the influence on planktonic and biofilm growth of four staphylococcus aureus strains were reported. the sequential exposure to carvacrol resulted in a direct protection that was more evident in two of the four strains after 10 days. no significant cross-protection against cinnamaldehyde, eugenol and antibiotics wa ... | 2017 | 28521511 |
| ethanol-induced stress response of staphylococcus aureus. | transcriptional profiles of 2 unrelated clinical methicillin-resistant staphylococcus aureus (mrsa) isolates were analyzed following 10% (v/v) ethanol challenge (15 min), which arrested growth but did not reduce viability. ethanol-induced stress (eis) resulted in differential gene expression of 1091 genes, 600 common to both strains, of which 291 were upregulated. with the exception of the downregulation of genes involved with osmotic stress functions, eis resulted in the upregulation of genes t ... | 2017 | 28521110 |
| relationship between toll-like receptor 2 r753q and t16934a polymorphisms and staphylococcus aureus nasal carriage. | the association among specific single-nucleotide polymorphisms (snps) in tlr2 r753q (rs5743708) and t16934a (rs4696480) and the nasal carriage of staphylococcus aureus was studied in adults before cabg. | 2017 | 28518213 |
| nasal decontamination for the prevention of surgical site infection in staphylococcus aureus carriers. | surgical site infection rates in the month following surgery vary from 1% to 5%. due to the large number of surgical procedures conducted annually, the costs of these surgical site infections (ssis) can be considerable in financial and social terms. nasal decontamination using antibiotics or antiseptics is performed to reduce the risk of ssis by preventing organisms from the nasal cavity being transferred to the skin where a surgical incision will be made. staphylococcus aureus (s aureus) coloni ... | 2017 | 28516472 |
| intracellular morphological changes in staphylococcus aureus induced by treatment with sodium hypochlorite. | sodium hypochlorite (naocl) is commonly used as a disinfectant; however, its bactericidal mechanism has not yet been clarified. in the present study, the bactericidal mechanism of naocl was examined using microscopy and gel electrophoresis techniques with staphylococcus aureus strain 209p. s. aureus cells treated with 500 and 1000 ppm naocl for 5 and 15 min were observed by sem and tem. sem images of the bacterial cells treated with naocl showed an irregular surface, with cells being partially i ... | 2017 | 28516285 |
| prevalence and comparing of some microbiological properties, somatic cell count and antibiotic residue of organic and conventional raw milk produced in turkey. | the aim of this study was to investigate the effects of production systems and milk collection periods on the somatic cell count (scc), some microbiological properties, total aerobic mesophilic bacteria (tamb), coliform, staphylococcus aureus (s. aureus), yeast and mould) and antibiotic residue of milk; in turkey. milk samples were collected from 9 conventional farms and 9 organic farms during one year time, at six different months (december 2013 to october 2014), and all farms were selected fro ... | 2017 | 28515650 |
| molecular typing and antimicrobial susceptibility of staphylococcus aureus strains isolated from raw milk, cheese, minced meat, and chicken meat samples. | the objectives of this study were: i) to detect the presence of staphylococcus aureus and methicillin-resistant s. aureus (mrsa) in raw milk, cheese, beef minced meat, and chicken meat samples; ii) to evaluate the antimicrobial susceptibility of the isolates; and iii) to determine clonal relation among the isolates by using pulsed-field gel electrophoresis (pfge) method. therefore, a total of 160 food samples were randomly collected between august 2014 and may 2015 in hatay province, located in ... | 2017 | 28515641 |
| acquisition of virulence factors in livestock-associated mrsa: lysogenic conversion of cc398 strains by virulence gene-containing phages. | staphylococcus aureus mrsa strains belonging to the clonal complex 398 (cc398) are highly prevalent in livestock and companion animals but may also cause serious infections in humans. cc398 strains in livestock usually do not possess well-known virulence factors that can be frequently found in other mrsa sequence types (st). since many staphylococcal virulence genes are residing on the genomes of temperate phages, the question arises why livestock-associated (la-) cc398 strains are only rarely i ... | 2017 | 28515479 |
| transmission of st8-usa300 latin american variant methicillin-resistant staphylococcus aureus on a neonatal intensive care unit: recurrent skin and soft- tissue infections as a marker for epidemic community-associated-mrsa colonization. | 2017 | 28514970 | |
| exposure to fermentation supernatant of staphylococcus aureus accelerated dedifferentiation of chondrocytes and production of antimicrobial peptides. | staphylococcus aureus (s. aureus) is the most popular pathogen found in septic arthritis. despite bacteria was eradicated from joint cavity during acute infection, destruction of articular cartilage often continues for years, leading to permanent joint damage. the mechanism responsible for this consistent catabolic reaction in septic arthritis remains unclear. here, we found that fermentation supernatant (fs) of s. aureus accelerated dedifferentiation of chondrocytes and induced expression of ca ... | 2017 | 28513981 |
| the structural basis for inhibition of the classical and lectin complement pathways by s. aureus extracellular adherence protein. | the extracellular adherence protein (eap) plays a crucial role in pathogenesis and survival of staphylococcus aureus by inhibiting the classical and lectin pathways of complement. we have previously shown that eap binds with nanomolar affinity to complement c4b and disrupts the initial interaction between c4b and c2, thereby inhibiting formation of the classical and lectin pathway c3 pro-convertase. although an underlying mechanism has been identified, the structural basis for eap binding to c4b ... | 2017 | 28512867 |
| an unusual case of methicillin-resistant staphylococcus aureus necrotic soft tissue infection of the lip. | 2017 | 28512754 | |
| laboratory mice are frequently colonized with staphylococcus aureus and mount a systemic immune response-note of caution for in vivo infection experiments. | whether mice are an appropriate model for s. aureus infection and vaccination studies is a matter of debate, because they are not considered as natural hosts of s. aureus. we previously identified a mouse-adapted s. aureus strain, which caused infections in laboratory mice. this raised the question whether laboratory mice are commonly colonized with s. aureus and whether this might impact on infection experiments. publicly available health reports from commercial vendors revealed that s. aureus ... | 2017 | 28512627 |
| mitral valve vegetation diagnosed with oesophageal ultrasound with bronchoscope (eus-b). | oesophageal ultrasound with bronchoscope (eus-b) is designed to evaluate mediastinal structures. we describe a case of a 78-year-old woman who presented with altered mental status for 2 weeks. ct head revealed a subacute infarct in the right middle cerebral artery distribution. she was also found to have a lung mass on chest imaging. eus-b-guided fine needle aspiration demonstrated the presence of adenocarcinoma in station 7 lymph node and in the mass. immunohistochemistry confirmed it to be a l ... | 2017 | 28512099 |
| highly effective antibacterial activity by the synergistic effect of three dimensional ordered mesoporous carbon-lysozyme composite. | aiming at developing a safe and efficient alternative to traditional drinking water disinfection, this work successfully synthesized a novel antibacterial material with high surface area, ultra large pore size and tunable loading of immobilized lysozyme. the immobilized enzymes exhibit high antibacterial efficacy without forming carcinogenic disinfection byproducts. critical immobilization parameters were optimized to keep the activity of the immobilized enzyme at a high level. the immobilizatio ... | 2017 | 28511102 |
| efflux pumps might not be the major drivers of qac resistance in methicillin-resistant staphylococcus aureus. | quaternary ammonium compounds (qacs) are commonly used antiseptics that are now known to be subject to bacterial resistance. the prevalence and mechanisms of such resistance, however, remain underexplored. we investigated a variety of qacs, including those with multicationic structures (multiqacs), and the resistance displayed by a variety of staphylococcus aureus strains with and without genes encoding efflux pumps, the purported main driver of bacterial resistance in mrsa. through minimum inhi ... | 2017 | 28510317 |
| molecular epidemiology of methicillin-resistant and methicillin-susceptible staphylococcus aureus in the ovine dairy chain and in farm-related humans. | staphylococcus aureus is a major cause of clinical infections in humans and its enterotoxins cause foodborne disease. in the present study, we tested a total of 51 isolates of s. aureus from small-ruminant dairy farms with artisan dairy facilities, all located in latium, italy. the farms have a known history of a high prevalence of methicillin-resistant s. aureus (mrsa). most of the mrsa isolates (27 of 51) belonged to spa-type t127 (43.1%), followed by t2678 (3.9%), t044 (2%), t1166 (2%), and t ... | 2017 | 28509842 |
| live-cell crispr imaging in plants reveals dynamic telomere movements. | elucidating the spatiotemporal organization of the genome inside the nucleus is imperative to our understanding of the regulation of genes and non-coding sequences during development and environmental changes. emerging techniques of chromatin imaging promise to bridge the long-standing gap between sequencing studies, which reveal genomic information, and imaging studies that provide spatial and temporal information of defined genomic regions. here, we demonstrate such an imaging technique based ... | 2017 | 28509419 |
| antimicrobial activity of two garlic species (allium sativum and a. tuberosum) against staphylococci infection. in vivo study in rats. | purpose: this study observed the effect of garlic extracts and amoxicillin against an induced staphylococcal infection model. mic and mbc were also obtained for aqueous extracts of allium sativum (asa) and allium tuberosum (atu) against staphylococcus aureus penicillin-sensitive (pssa - atcc 25923) and mrsa (atcc 33592). methods: granulation tissues were induced in the back of 205 rats. after 14 days, 0.5 ml of 10(8) cfu/ml of pssa or mrsa were injected inside tissues. after 24h, animals were di ... | 2017 | 28507945 |
| patient engagement with surgical site infection prevention: an expert panel perspective. | despite remarkable developments in the use of surgical techniques, ergonomic advancements in the operating room, and implementation of bundles, surgical site infections (ssis) remain a substantial burden, associated with increased morbidity, mortality and healthcare costs. national and international recommendations to prevent ssis have been published, including recent guidelines by the world health organization, but implementation into clinical practice remains an unresolved issue. ssi improveme ... | 2017 | 28507731 |
| inhibition of staphylococcus aureus cell wall biosynthesis by desleucyl-oritavancin: a quantitative peptidoglycan composition analysis by mass spectrometry. | oritavancin is a lipoglycopeptide antibiotic that exhibits potent activities against vancomycin-resistant gram-positive pathogens. oritavancin differs from vancomycin by a hydrophobic side chain attached to the drug disaccharide, which forms a secondary binding site to enable oritavancin binding to the cross-linked peptidoglycan in the cell wall. the mode of action of secondary binding site was investigated by measuring the changes in the peptidoglycan composition of staphylococcus aureus grown ... | 2017 | 28507244 |
| controlled release of plectasin nz2114 from a hybrid silicone-hydrogel material for inhibition of staphylococcus aureus biofilm. | staphylococcus aureus is a major human pathogen in catheter-related infections. modifying catheter material with interpenetrating polymer networks is a novel material technology that allows for impregnation with drugs and subsequent controlled release. here, we evaluated the potential for combining this system with plectasin derivate nz2114 in an attempt to design an s. aureus biofilm-resistant catheter. the material demonstrated promising antibiofilm properties, including properties against met ... | 2017 | 28507110 |
| reduced vancomycin susceptibility of methicillin-susceptible staphylococcus aureus has no significant impact on mortality but results in an increase in complicated infection. | methicillin-susceptible staphylococcus aureus (mssa) bloodstream infections (bsis) often lead to severe complications despite the availability of effective antibiotics. it remains unclear whether elevated vancomycin mics are associated with worse outcomes. we conducted a 2-year retrospective cohort study (n = 252) of patients with mssa bsis at a tertiary care hospital. we defined reduced vancomycin susceptibility (rvs) as a microscan mic of 2 mg/liter. all strains were genotyped (spa) and assess ... | 2017 | 28507105 |
| saers is responsive to cellular respiratory status and regulates fermentative biofilm formation in staphylococcus aureus. | biofilms are multicellular communities of microorganisms living as a quorum rather than as individual cells. the bacterial human pathogen staphylococcus aureus uses oxygen as a terminal electron acceptor during respiration. infected human tissues are hypoxic or anoxic. we recently reported that impaired respiration elicits a programmed cell lysis (pcl) phenomenon in s. aureus leading to the release of cellular polymers that are utilized to form biofilms. pcl is dependent upon the atla murein hyd ... | 2017 | 28507069 |
| old drug, new wrapping - a possible comeback for chloramphenicol? | the antimicrobial drug chloramphenicol (cam) exhibits activity against resistant bacteria, such as methicillin-resistant staphylococcus aureus (mrsa). however, its use has been limited due to its toxicity. as the threat of antibiotic resistance continues to grow, a promising approach might be to increase the use of historical antimicrobial agents that demonstrate clinical efficacy, but are hampered by toxicity. we therefore aimed to prepare a liposome-in-hydrogel system for dermal delivery of ca ... | 2017 | 28506801 |
| correspondence analysis to evaluate the transmission of staphylococcus aureus strains in two new york state maximum-security prisons. | prisons/jails are thought to amplify the transmission of staphylococcus aureus (sa) particularly methicillin-resistant sa infection and colonisation. two independently pooled cross-sectional samples of detainees being admitted or discharged from two new york state maximum-security prisons were used to explore this concept. private interviews of participants were conducted, during which the anterior nares and oropharynx were sampled and assessed for sa colonisation. log-binomial regression and co ... | 2017 | 28506332 |
| antimicrobial resistance profile of staphylococcus aureus isolates isolated from ear discharges of patients at university of hawassa comprehensive specialized hospital. | drug-resistant microorganism are a growing global danger. strains of s. aureus have developed resistance to many commonly used antimicrobials due to indiscriminate use of antimicrobials, and treatment becoming a challenge. studies assessing pattern and determinants of s. aureus resistance in ear infection in ethiopia are very scarce. this study presents overview of pattern and determinants s. aureus resistance from samples of ear discharge in ethiopia. | 2017 | 28506250 |
| intramammary inoculation of panax ginseng plays an immunoprotective role in staphylococcus aureus infection in a murine model. | the immunoprotective effect of panax ginseng (pg) extract was investigated in a mouse mastitis model. lactating female mice were intramammarily inoculated with pg or placebo, and then were challenged with s. aureus, while other group was inoculated with s. aureus alone. the number of bacteria recovered from mammary glands was significantly lower in pg-treated s. aureus-infected mice (group i) compared with placebo-treated s. aureus-infected mice (group ii) and s. aureus-infected mice (group iii) ... | 2017 | 28505549 |
| structural basis for xenosiderophore utilization by the human pathogen staphylococcus aureus. | staphylococcus aureus produces a cocktail of metallophores (staphylopine, staphyloferrin a, and staphyloferrin b) to scavenge transition metals during infection of a host. in addition, s. aureus displays the extracellular surface lipoproteins fhud1 and fhud2 along with the abc transporter complex fhucbg to facilitate the use of hydroxamate xenosiderophores such as desferrioxamine b (dfob) for iron acquisition. dfob is used as a chelation therapy to treat human iron overload diseases and has been ... | 2017 | 28505405 |
| synthesis, antifungal and antibacterial activity of novel 1,2,4-triazole derivatives. | a large number of 1,2,4-triazole-containing ring system have been incorporated into a wide variety of therapeutically interesting drug candidates including anti-inflammatory, central nervous system stimulants, antianxiety, and antimicrobial agents. to overcome the rapid development of drug resistance, new agents should preferably have chemical characteristics that clearly differ from those of existing agents. thus led to the design and synthesize the new antimicrobial agents. a novel series of s ... | 2017 | 26317080 |
| aspergillus terreus brain abscess complicated by tension pneumocephalus in a patient with angiosarcoma. | background aspergillus terreus is an evolving opportunistic pathogen, and patients with a. terreus often have poor outcomes due to its intrinsic resistance to several systemic antifungal agents. here we present a unique case of intracranial abscesses of a. terreus in a patient with recurrent angiosarcoma, complicated by development of tension pneumocephalus. case report a 67-year old gentleman with history of scalp angiosarcoma with wide excision two years prior presented to the hospital for lef ... | 2017 | 28070116 |
| isolation and identification of phase i metabolites of butyrolactone i in rats. | 1. butyrolactone i (bl-i), one of the major secondary metabolites of fungus aspergillus terreus, is a selective cdc2 kinase inhibitor. in the present study, the metabolism of bl-i in male wistar rats was investigated by characterizing metabolites excreted into feces. 2. following an oral dose of 40 mg/kg bl-i, 10 phase i metabolites were isolated from the feces of rats, and their structures were identified on the basis of a range of spectroscopic data and icd analysis. these metabolites were ful ... | 2017 | 27604497 |
| evaluating bionanoparticle infused fungal metabolites as a novel antimicrobial agent. | therapeutic properties of fungal metabolites and silver nanoparticles have been well documented. while fungal metabolites have been used for centuries as medicinal drugs, potential of biogenic silver nanoparticles has recently received attention. we have evaluated the antimicrobial potential of aspergillus terreus crude extract, silver nanoparticles and an amalgamation of both against four pathogenic bacterial strains. antimicrobial activity of the following was evaluated - a. terreus extract, b ... | 2017 | 27429931 |
| new metabolites from the sponge-derived fungus aspergillus sydowii j05b-7f-4. | two new metabolites, diorcinolic acid (1) and β-d-glucopyranosyl aspergillusene a (8), together with six diphenylethers (2-7), a diketopiperazine (9), a chromone (10) and a xanthone (11) were isolated from the fungus aspergillus sydowii derived from the marine sponge stelletta sp. the planar structures and their relative configurations were elucidated by analysing 1d, 2d nmr and hresims data. compound 8 is the first glycoside of phenolic bisabolane sesquiterpenes. compounds 1 and 8 exhibited mil ... | 2017 | 28278674 |
| combating drug resistant pathogenic bacteria isolated from clinical infections, with silver oxide nanoparticles. | the antibiogram study of methicillin resistant staphylococcus aureus isolates revealed 100% resistance to vancomycin, bacitracin, erythromycin, ciprofloxacin and nalidixic acid. eight isolates (53.3%) showed resistance to co-trimoxazole and one isolate to rifampicin, which was the drug of choice. an effort was made to evaluate the antimethicillin resistant staphylococcus aureus activity of silver oxide (ag2o) nanoparticles synthesized from aspergillus terreus vit 2013. production of ag2o nanopar ... | 2017 | 26009646 |
| development of antibacterial conjugates using sulfamethoxazole with monocyclic terpenes: a systematic medicinal chemistry based computational approach. | to develop 6 conjugate agents of the moribund antibiotic sulfamethoxazole (smz) joined to 6 individual monoterpenes, followed by protocols of medicinal chemistry as potent antibacterials, against multidrug resistant (mdr) human gruesome pathogenic bacteria. | 2017 | 28254074 |
| isolation, characterization and antimicrobial activities of polyacetylene glycosides from coreopsis tinctoria nutt. | polyacetylene glycosides, (6z, 12e)-tetradecadiene-8,10-diyne-1-ol-3(r)-o-β-d-glucopyranoside (trivially named coreoside e) and (6z, 12e)-tetradecadiene-8,10-diyne-1-ol-3(r)-o-β-l-arabinopyranosyl-(1 → 2)-β-d-glucopyranoside (trivially named coreoside f), were isolated from buds of coreopsis tinctoria nutt., together with one known compound, coreoside b. their chemical structures were elucidated by extensive spectroscopic analysis and on the basis of their chemical reactivities. coreoside e exhi ... | 2017 | 28104231 |
| transcriptional classification and functional characterization of human airway macrophage and dendritic cell subsets. | the respiratory system is a complex network of many cell types, including subsets of macrophages and dendritic cells that work together to maintain steady-state respiration. owing to limitations in acquiring cells from healthy human lung, these subsets remain poorly characterized transcriptionally and phenotypically. we set out to systematically identify these subsets in human airways by developing a schema of isolating large numbers of cells by whole-lung bronchoalveolar lavage. six subsets of ... | 2017 | 28031342 |
| design, synthesis and antimicrobial activities of thiouracil derivatives containing triazolo-thiadiazole as seca inhibitors. | a series of novel thiouracil derivatives containing a triazolo-thiadiazole moiety (7a-7l) have been synthesized by structural modifications on a lead seca inhibitor, 2. all the compounds have been evaluated for their antibacterial activities against bacillus amyloliquefaciens, staphylococcus aureus, and bacillus subtilis. compounds 7d and 7g were also tested for their inhibitory activities against seca atpase due to their promising antimicrobial activities. the inhibitory activity of compound 7d ... | 2017 | 28039774 |
| potential immunomodulatory effects of non-dialyzable materials of cranberry extract in poultry production. | studies on effects of cranberry products in animals, especially in chickens, are very scarce or even lacking. this study investigated the immunomodulatory effect of high molecular weight non-dialyzable materials (ndms) of cranberry extract. the in vitro antioxidant and anti-inflammatory activities were investigated. the ability of ndms (0, 1, 2, or 4 mg/ml) to enhance phagocytic activities was also evaluated using chicken heterophils (ches) against staphylococcus aureus furthermore, a broiler mo ... | 2017 | 27587728 |
| rapid and sensitive detection of mycoplasma synoviae by an insulated isothermal polymerase chain reaction-based assay on a field-deployable device. | mycoplasma synoviae (ms), causing respiratory diseases, arthritis, and eggshell apex abnormalities in avian species, is an important pathogen in the poultry industry. implementation of a biosecurity plan is important in ms infection management. working on a field-deployable pockit™ device, an insulated isothermal polymerase chain reaction (iipcr) assay has a potential for timely ms detection on the farm. the ms iipcr assay had limit of detection 95% of about 9 genome equivalents by testing seria ... | 2017 | 27389062 |
| fermentation of sarshir (kaymak) by lactic acid bacteria: antibacterial activity, antioxidant properties, lipid and protein oxidation and fatty acid profile. | the antioxidant and antibacterial activity of fermented sarshir (traditional dairy food), with three probiotic lactobacillus plantarum strains (lp3, af1, and lu5) were investigated. the oxidative stability and lipid profile of non-fermented and fermented sarshir were compared, as well as radical scavenging activity, peroxide, anisidine, and carbonyl values (pv, anv, and cv, respectively). | 2017 | 28349539 |
| cytotoxicity, bactericidal, and antioxidant activity of sodium alginate hydrosols treated with direct electric current. | the aim of the study was to investigate the effect of using direct electric current (dc) of 0, 200, and 400 ma for five minutes on the physiochemical properties, cytotoxicity, antibacterial, and antioxidant activity of sodium alginate hydrosols with different sodium chloride concentrations. the ph, oxidation-reduction potential (orp), electrical conductivity (ec), and available chlorine concentration (acc) were measured. the effect of sodium alginate hydrosols treated with dc on staphylococcus a ... | 2017 | 28327520 |
| cellulase-assisted extraction of polysaccharides from malva sylvestris: process optimization and potential functionalities. | enzyme-assisted extraction process of the water-soluble malva sylvestris polysaccharides (msps) was optimized using response surface methodology (rsm). the highest yield (10.40%) of msps was achieved at 5.64% cellulase, 55.65°c temperature, 3.4h time, and 5.22 ph. three homogeneous polysaccharide fractions (msp-1, msp-2, msp-3) were purified by deae-cellulose and sephadex g-100 chromatography, which were composed of galactose, glucuronic acid, arabinose, rhamnose and mannose in different molar r ... | 2017 | 28327424 |
| biofilm inhibition formation of clinical strains of pseudomonas aeruginosa mutans, photocatalytic activity of azo dye and gc-ms analysis of leaves of lagerstroemia speciosa. | the investigation was conducted to analyse the bioactive compounds from the leaf extracts of l. speciosa by gc-ms. the extracts were screened for antibacterial and antibiofilm activities against potential clinical strains. the bioactive compounds from the leaves of l. speciosa were extracted by soxhlet continuous extraction method and their chemical composition was analysed by gas chromatography-mass spectroscopy (gc-ms). the antibacterial activity was evaluated against clinical strain like stap ... | 2017 | 28319869 |
| exploiting fruit byproducts for eco-friendly nanosynthesis: citrus × clementina peel extract mediated fabrication of silver nanoparticles with high efficacy against microbial pathogens and rat glial tumor c6 cells. | process byproducts from the fruit industry may represent a cheap and reliable source of green reducing agents to be used in current bio-nanosynthesis. this study reports the use of orange (citrus × clementina) peel aqueous extract (ope) for one-pot green synthesis of silver nanoparticles (agnps) with high effectiveness against various microbial pathogens as well as rat glial tumor c6 cells. the effects of various operational parameters on the synthesis of agnps were systematically investigated. ... | 2017 | 28303540 |
| in vitro antibacterial, antifungal and antioxidant activities of eucalyptus spp. leaf extracts related to phenolic composition. | the crude methanolic extracts from leaves of eucalyptus camaldulensis l., e. camaldulensis var obtusa and e. gomphocephala grown in egypt were investigated to explore their chemical composition as well as their antibacterial, antifungal and antioxidant activities. major phenolics found were ellagic acid, quercetin 3-o-rhamnoside, quercetin 3-o-b-d-glucuronide, caffeic acid and chlorogenic acid. the antioxidant activities were examined by the 2,2'-diphenypicrylhydrazyl (dpph) and β-carotene-linol ... | 2017 | 28299978 |
| chemical composition and biological properties of satureja avromanica maroofi. | satureja avromanica is an indigenous plant which is frequently used as a spice in avraman-kurdistan region of iran. the present study aimed to investigate the chemical composition, antimicrobial and antioxidant properties of the s. avromanica. in addition, rosmarinic acid and total phenolic content of s. avromanica was assessed by spectrophotometric method and hptlc. the essential oil and methanolic extract were isolated by hydrodistillation and maceration methods, respectively. a total of 32 co ... | 2017 | 28298686 |
| antibacterial activity and synergistic antibacterial potential of biosynthesized silver nanoparticles against foodborne pathogenic bacteria along with its anticandidal and antioxidant effects. | silver nanoparticles plays a vital role in the development of new antimicrobial substances against a number of pathogenic microorganisms. these nanoparticles due to their smaller size could be very effective as they can improve the antibacterial activity through lysis of bacterial cell wall. green synthesis of metal nanoparticles using various plants and plant products has recently been successfully accomplished. however, few studies have investigated the use of industrial waste materials in nan ... | 2017 | 28261161 |
| should we care about transmission of infectious bacterial agents through serum handling? | immunological assays are valuable diagnostic tools to detect infections due to most of bacterial microorganisms. however, the question is how much safe are the common serum samples used as sources of antibodies in these assays? here, we experimentally followed the issue. 10-fold serial dilutions of two gram-positive, staphylococcus aureus and bacillus cereus, and one gram-negative bacteria, escherichia coli, were prepared and spiked into freshly taken blood samples of human and four animal speci ... | 2017 | 28242424 |
| the antibacterial activity of extracts of nine plant species with good activity against escherichia coli against five other bacteria and cytotoxicity of extracts. | the development of antibiotic resistant bacteria stems from a number of factors, including inappropriate use of antibiotics in human and animal health and their prolonged use as growth promoters at sub-clinical doses in poultry and livestock production. we were interested in investigating plants that could be useful in protecting humans or animals against diarrhoea. we decided to work on extracts of nine plant species with good activity against escherichia coli based on earlier work in the phyto ... | 2017 | 28241818 |
| synthetic investigation, physicochemical characterization and antibacterial evaluation of ternary bi(iii) systems with hydroxycarboxylic acid and aromatic chelator substrates. | due to its physical and chemical properties, bismuth (bi(iii)) is widely used in the treatment of several gastrointestinal and skin diseases, and infections caused by bacteria. herein, its known antimicrobial potential was taken into consideration in the synthesis of two new hybrid ternary materials of bi(iii) with the physiological α-hydroxycarboxylic glycolic acid and 1,10-phenanthroline (phen), [bi2(c2h2o3)2(c2h3o3)(no3)]n(.) nh2o (1) and [bi(c12h8n2)(no3)4](c10h8n4) (2), aiming at improving ... | 2017 | 28231455 |