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mortality from infective endocarditis: clinical predictors of outcome.to identify clinical markers available within the first 48 hours of admission that are associated with poor outcome in infective endocarditis.200212067945
acute septic arthritis.acute septic arthritis may develop as a result of hematogenous seeding, direct introduction, or extension from a contiguous focus of infection. the pathogenesis of acute septic arthritis is multifactorial and depends on the interaction of the host immune response and the adherence factors, toxins, and immunoavoidance strategies of the invading pathogen. neisseria gonorrhoeae and staphylococcus aureus are used in discussing the host-pathogen interaction in the pathogenesis of acute septic arthrit ...200212364368
bilateral endogenous endophthalmitis caused by hacek microorganism.to report a case of bilateral endogenous endophthalmitis caused by a hacek group organism (actinobacillus actinomycetemcomitans).200211755854
[kingella kingae: occult bacteriemia in a child]. 200211827663
[kingella kingae: a rare cause of meningitis].kingella kingae is the second most frequent germ involved in arthritis affecting young children. this germ isolation on ordinary environment is difficult, which may explain why it is seldom known. it is now widely accepted that a direct inoculate of articular and osseous samples on liquid substrate improves the culture sensitivity. other septic localizations have been described such as endocarditis or, less commonly, meningitis. case report: we report the observation of a five-year-old child, tr ...200211865547
nontuberculous spondylodiscitis in children.forty-two children with nontuberculous spondylodiscitis treated between 1966 and 1997 were reviewed, and the clinical, paraclinical, and therapeutic results are presented. the study shows the difficulties of diagnosis and understanding the pathophysiology of the disease. additional information is provided by new imaging techniques, disc aspiration, and biopsy. the mean age at treatment was 4 years 6 months. the initial clinical presentation was often misleading and the diagnosis was often delaye ...200211961447
epidemiological features of invasive kingella kingae infections and respiratory carriage of the organism.the age, sex, and seasonal distributions of invasive kingella kingae infections in southern israel were examined and compared to the epidemiology of respiratory carriage of the organism. medical records of all patients diagnosed between 1988 and 2002 were reviewed, and 2,044 oropharyngeal specimens were cultured on selective media during two periods (february to may and october to december) in 2001. invasive infections significantly affected children (73 of 74 patients [98.6%] were younger than ...200212409394
combined antibiotic and free radical trap treatment is effective at combating staphylococcus-aureus-induced septic arthritis.although early antibiotic treatment of patients with septic arthritis eradicates bacteria, joint destruction commonly results from the unregulated host inflammatory responses to infection. the spin trap compound phenyl-n-tert-butyl nitrone (pbn) has been shown to have both anti-inflammatory and antioxidant effects. the aim of this study was to assess the effect of combined systemic administration of pbn and cloxacillin on the development of staphylococcus aureus arthritis.three days after naval ...200212010570
[endocarditis due to hacek bacteria. a case report of endocarditis due to kingella kingae].endocarditis is a common disease in hospital practice. identification of the microorganism responsible for the valvular damage is essential to establish the prognosis and to determine the optimal antibiotic treatment. in some cases of endocarditis the diagnosis is laborious, especially when the responsible microorganism is difficult to detect using standard culture techniques. here we report a case of native aortic valve endocarditis due to kingella kingae, a gram negative organism of the hacek ...200111234709
soft tissue infection caused by kingella kingae in a child.during the last years an increasing number of reports concerning kingella kingae infections in children has been published. most cases were osteoarticular infections. the authors report the clinical and laboratory findings from a 3-year-old child with a presternal soft tissue infection due to k kingae. after surgical excochleation and antibiotic treatment there was an uneventful recovery. j pediatr surg 36:946-947.200111381434
whipple's disease and "tropheryma whippelii".whipple's disease is a rare bacterial infection that may involve any organ system in the body. it occurs primarily in caucasian males older than 40 years. the gastrointestinal tract is the most frequently involved organ, with manifestations such as abdominal pain, malabsorption syndrome with diarrhea, and weight loss. other signs include low-grade fever, lymphadenopathy, skin hyperpigmentation, endocarditis, pleuritis, seronegative arthritis, uveitis, spondylodiscitis, and neurological manifesta ...200111432814
septic arthritis due to kingella kingae in an adult. 200111235790
[kingella kingae osteomyelitis].a case of kingella kingae osteomyelitis in a 1-year-old child is described. kingella kingae osteoarticular infections in children and the difficulties of isolating this slow growing, fastidious bacterium are discussed.200111723690
[kingella kingae endocarditis]. 200111852509
optimisation of the prevention and treatment of bacterial endocarditis.this paper reviews currently established guidelines for the prevention and treatment of bacterial endocarditis. endocarditis remains a life-threatening disease with substantial morbidity and mortality. primary prevention of endocarditis, whenever possible, is therefore very important. in an individual with endocarditis, rapid diagnosis and effective treatment are essential to good patient outcome. the guidelines discussed here are largely based on those issued by the american heart association. ...200111419916
production of bartonella genus-specific monoclonal antibodies.monoclonal antibodies (mabs) which react with heat-resistant proteins with molecular masses of 32 to 33 kda of 14 different bartonella species were produced. these antibodies did not react with antigens of 26 diverse bacterial strains by microimmunofluorescence assay except mab b3d4, which reacted with chlamydia psittaci and chlamydia trachomatis at low titers. the identification of a common bartonella antigenic protein will make it possible to later produce a diagnostic antigen by cloning and e ...200111427441
structural and genetic analyses of o polysaccharide from actinobacillus actinomycetemcomitans serotype f.the oral bacterium actinobacillus actinomycetemcomitans is implicated as a causative agent of localized juvenile periodontitis (ljp). a. actinomycetemcomitans is classified into five serotypes (a to e) corresponding to five structurally and antigenically distinct o polysaccharide (o-ps) components of their respective lipopolysaccharide molecules. serotype b has been reported to be the dominant serotype isolated from ljp patients. we determined the lipopolysaccharide o-ps structure from a. actino ...200111500407
endocarditis due to rare and fastidious bacteria.the etiologic diagnosis of infective endocarditis is easily made in the presence of continuous bacteremia with gram-positive cocci. however, the blood culture may contain a bacterium rarely associated with endocarditis, such as lactobacillus spp., klebsiella spp., or nontoxigenic corynebacterium, salmonella, gemella, campylobacter, aeromonas, yersinia, nocardia, pasteurella, listeria, or erysipelothrix spp., that requires further investigation to establish the relationship with endocarditis, or ...200111148009
antibiotic susceptibility of kingella kingae isolates from respiratory carriers and patients with invasive infections.the antimicrobial drug susceptibilities of 145 isolates of kingella kingae to eight antibiotics were determined by the disc diffusion method. in addition, penicillin mics were determined by the etest. study isolates included 37 from blood, 34 from the skeletal system and 74 from respiratory carriers. all isolates were beta-lactamase negative and susceptible to erythromycin, gentamicin, chloramphenicol, tetracycline and ciprofloxacin. a single isolate exhibited resistance to trimethoprim-sulphame ...200111157905
use of bactec 9240 blood culture system for detection of brucella melitensis in synovial fluid.synovial fluid specimens aspirated from patients with arthritis were inoculated into an aerobic peds plus blood culture bottle and monitored by the bactec 9240 instrument for 4 weeks. a total of 1,072 synovial fluid cultures were processed, and 15 (0.14%) were positive for brucella melitensis. a single culture, harboring 1.3 cfu of viable organisms per ml, was missed by the instrument. all 14 positive bactec cultures were detected within 3 to 7 days.200111158139
two cases of diskitis attributable to anaerobic bacteria in children.diskitis, an inflammation of the intervertebral disk, is generally attributable to staphylococcus aureus and rarely staphylococcus epidermidis, kingella kingae, enterobacteriaciae, and streptococcus pneumoniae. in many cases, no bacterial growth is obtained from infected intervertebral discs. although anaerobic bacteria were recovered from adults with spondylodiscitis, these organisms were not reported before from children. the recovery of anaerobic bacteria in 2 children with diskitis is report ...200111158500
diagnostics of neisseriaceae and moraxellaceae by ribosomal dna sequencing: ribosomal differentiation of medical microorganisms.fast and reliable identification of microbial isolates is a fundamental goal of clinical microbiology. however, in the case of some fastidious gram-negative bacterial species, classical phenotype identification based on either metabolic, enzymatic, or serological methods is difficult, time-consuming, and/or inadequate. 16s or 23s ribosomal dna (rdna) bacterial sequencing will most often result in accurate speciation of isolates. therefore, the objective of this study was to find a hypervariable ...200111230407
kingella kingae endocarditis in a sixteen-month-old-child.we report the case of a child with acute neurologic symptoms who was found to have bacterial endocarditis caused by kingella kingae. the case alerts microbiologists and pediatricians to an organism that has rarely been reported to cause endocarditis in children.200111332678
bacterial diversity in human subgingival plaque.the purpose of this study was to determine the bacterial diversity in the human subgingival plaque by using culture-independent molecular methods as part of an ongoing effort to obtain full 16s rrna sequences for all cultivable and not-yet-cultivated species of human oral bacteria. subgingival plaque was analyzed from healthy subjects and subjects with refractory periodontitis, adult periodontitis, human immunodeficiency virus periodontitis, and acute necrotizing ulcerative gingivitis. 16s ribos ...200111371542
recurrent soft tissue abscesses caused by legionella cincinnatiensis.recurrent soft tissue abscesses of the jaw, wrist, and arm developed in a 73-year-old housewife with nephrotic syndrome and immunoglobulin a(kappa) gammopathy of unknown etiology. conventional cultures remained negative, despite visible gram-negative rods on microscopy. broad-spectrum pcr revealed legionella cincinnatiensis, which was confirmed by isolation of the organism on special legionella medium. infections due to legionella species outside the lungs are rare. l. cincinnatiensis has been i ...200111724886
review article: paediatric bone and joint infection.paediatric musculoskeletal infection remains an important cause of morbidity. methicillin sensitive staphylococcus aureus is still the most common organism although the incidence of methicillin resistant s. aureus in the community is rising. osteomyelitis and septic arthritis due to haemophilus influenzae is decreasing in incidence secondary to immunisation and in some units has been replaced by infections with the gram negative bacillus, kingella kingae. recent prospective studies indicate that ...200112468850
culture with bactec peds plus/f bottle compared with conventional methods for detection of bacteria in synovial fluid.an evaluation was undertaken to determine the utility of the bactec peds plus/f bottle and the bactec 9240 instrument (becton dickinson diagnostic instrument systems, sparks, md.) for the detection of clinically significant microorganisms in synovial fluid specimens. the peds plus/f bottle was used because in our laboratory the quantity of synovial fluid available for culture is frequently in the range of 0.5 to 3.0 ml. the culture results obtained with the peds plus/f bottle were compared to th ...200111724863
kingella kingae infections in children.to increase awareness of kingella kingae infections in children by presenting four cases seen at the gold coast hospital, southport, queensland, and reviewing the literature.200010723701
global aphasia without hemiparesis secondary to kingella kingae endocarditis. 200011115245
isolation of pantoea agglomerans in two cases of septic monoarthritis after plant thorn and wood sliver injuries.arthritis after plant injury is often apparently aseptic. we report two cases due to pantoea agglomerans. in one case, the bacterium was isolated only from the pediatric blood culture media, bactec peds plus, monitored in bactec 9240, and not from the other media inoculated with the joint fluid. this procedure could help improve the diagnosis of septic arthritis.200010618144
population-based study of invasive kingella kingae infections. 200010653579
importance of kingella kingae as a pediatric pathogen in the united states. 200010749477
kingella endocarditis and meningitis in a patient with sle and associated antiphospholipid syndrome.we describe a patient with sle and antiphospholipid syndrome who presented with severe headache and fever. lumbar puncture analyses indicated meningitis. kingella kingae was isolated from her blood cultures. a large mobile vegetation was seen on her mitral valve. the association between sle, libman-sacks endocarditis and bacterial endocarditis is discussed.200010878736
[kingella kingae osteoarticular infections in children. a report of a series of eight new cases].kingella kingae is a gram-negative bacillus which belongs to the neisseriaceae family. its involvement in osteoarticular infections is relatively recent.200011028199
nonspecific adherence by actinobacillus actinomycetemcomitans requires genes widespread in bacteria and archaea.the gram-negative coccobacillus, actinobacillus actinomycetemcomitans, is the putative agent for localized juvenile periodontitis, a particularly destructive form of periodontal disease in adolescents. this bacterium has also been isolated from a variety of other infections, notably endocarditis. fresh clinical isolates of a. actinomycetemcomitans form tenacious biofilms, a property likely to be critical for colonization of teeth and other surfaces. here we report the identification of a locus o ...200011029439
[kingella kingae in a 10-year-old girl]. 200011109731
isolation of kingella kingae from synovial fluids using four commercial blood culture bottles.according to the literature, kingella kingae may be an underdiagnosed cause of joint and bone infections in children. the use of the bactec blood culture system for culture of joint fluids has dramatically improved the isolation of this fastidious bacterium. the aim of this study was to test the recovery rate and detection time of four commercial blood culture systems: three different bact/alert (organon teknika, usa) bottles and one bactec (becton dickinson microbiology systems, usa) bottle, al ...200011014623
[septic arthritis in two young children caused by unusual gram-negative pathogens].two children, a girl aged 2 years and a boy aged 10 months, were moderately ill with signs of inflammation of the left and the right knee, respectively. both had had pharyngitis, and the boy also had paronychia of the right foot. the gram preparation of synovial fluid showed gram-positive cocci in the girl, while kingella kingae was cultured. in the boy, a moraxella was cultured from the synovial fluid using an aerobic blood culture system. both recovered without sequelae after adequate antibiot ...200010941437
[kingella kingae ostemyelitis and septic arthritis in paediatric patients. six cases from the department of pediatrics, national university hospital of iceland.]kingella kingae (k. kingae) is a gram negative rod most often associated with septic arthritis and osteomyelitis in children. infections caused by k. kingae had not been reported in iceland when six cases were diagnosed at the pediatric department at the national university hospital of iceland. in this report we describe those cases and review the literature.200017018942
a rare manifestation of kingella kingae infection.kingella kingae is an aerobic gram-negative coccobacillus that has been associated predominantly with bone and joint infection but also with septicemia and endocarditis. until now, only four cases of proven k. kingae meningitis have been reported. we describe a case of a k. kingae meningitis in a male adolescent who presented with a history of fever of unclear origin.200011113660
nested duplex pcr to detect bordetella pertussis and bordetella parapertussis and its application in diagnosis of pertussis in nonmetropolitan southeast queensland, australia.a duplex pcr to detect bordetella pertussis and bordetella parapertussis was developed with the insertion sequences is481 (b. pertussis) and is1001 (b. parapertussis) and evaluated with specimens from 520 consecutive patients presenting with possible pertussis. no culture-positive-pcr-negative results occurred, giving the method a sensitivity of 100%. for b. pertussis, 58 of 520 patients (11.2%) were positive by pcr compared to 17 of 520 patients positive (3.3%) by culture. for b. parapertussis, ...19999986820
etiology of septic arthritis in children: an update for the 1990s.to establish the etiology of septic arthritis in children after implementation of hib immunization guidelines.199910069312
[osteoarticular infection by kingella kingae: two case reports]. 199910394189
gliding motility in bacteria: insights from studies of myxococcus xanthus.gliding motility is observed in a large variety of phylogenetically unrelated bacteria. gliding provides a means for microbes to travel in environments with a low water content, such as might be found in biofilms, microbial mats, and soil. gliding is defined as the movement of a cell on a surface in the direction of the long axis of the cell. because this definition is operational and not mechanistic, the underlying molecular motor(s) may be quite different in diverse microbes. in fact, studies ...199910477310
diagnosis of kingella kingae arthritis by polymerase chain reaction analysis. 199910530485
kingella kingae prosthetic valve endocarditis. 199910547947
use of blood culture systems for isolation of kingella kingae from synovial fluid. 199910610378
recovery of kingella kingae from blood and synovial fluid of two pediatric patients by using the bact/alert system. 199910084890
molecular identification of gemella species from three patients with endocarditis.gemella morbillorum and gemella haemolysans are opportunistic pathogens which cause endocarditis and other severe infections. we report on three patients with endocarditis, one with endocarditis caused by g. haemolysans and two with endocarditis caused by g. morbillorum. the paucity of reports concerning these bacteria is probably related to the difficulties associated with their identification. for example, one of the strains reported in this study was originally sent to our laboratory with a p ...19989542900
person-to-person transmission of kingella kingae among day care center attendees.fifty kingella kingae organisms, isolated from tonsillar cultures of day care center attendees during an 11-month period, and 60 isolates derived from epidemiologically unrelated individuals, including 19 isolates from respiratory carriers and 41 isolates from patients with invasive infections, were typed by immunoblotting, pulsed-field gel electrophoresis, and ribotyping. one strain, defined by unique immunoblotting, pulsed-field gel electrophoresis, and ribotyping patterns, represented 14 day ...19989815248
[multifocal invasive kingella kingae infection].case report: a 2-year-old child, non immunodeficient, presented with septicemia due to kingella kingae successively complicated by meningitis, arthritis of one knee and endocarditis. outcome was favourable after a long and adjusted antibiotherapy, involving in particular for the endocarditis ceftriaxone (100 mg/kg/d) and amikacin (20 mg/kg/d) during 3 weeks, then amoxicillin per os (200 mg/kg/d) during 3 weeks. conclusions: bacteriologic characteristics of the bacteria, the culture of which requ ...199810223137
increasing prevalence of kingella kingae in osteoarticular infections in young children.sixty children younger than 3 years with culture-positive hematogenous septic arthritis and acute/subacute osteomyelitis treated between 1990 and 1995 were reviewed to identify the infecting organism. gram-positive bacteria were identified in 47 (78.3%) patients, and gram-negative organisms were identified in 13 (21.7%) patients. haemophilus influenzae was cultured in none of the cases of septic arthritis and in only one (1.6%) case of acute osteomyelitis. kingella kingae was cultured in 10 (16. ...19989531414
[osteomyelitis of the astragalus caused by kingella kingae]. 19989666597
antibody response in six hacek endocarditis cases under therapy.the antibody response to bacteria of the so-called hacek group, i.e. haemophilus spp., actinobacillus actinomycetemcomitans, cardiobacterium hominis, eikenella corrodens and kingella kingae, was measured in sera of six patients with endocarditis. the corresponding isolates from their blood cultures were identified by conventional methods, including reactions for nitrate reduction and catalase as well as acid production from sugars. crude antigens were prepared by glycine extraction and sonificat ...19989674892
invasive kingella kingae infection associated with stomatitis in children. 19989726357
five cases of kingella kingae skeletal infection in a french hospital.five cases of kingella kingae skeletal infections were diagnosed in children admitted to la timone hospital between 1992 and 1997. patients were between 6 and 31 months old and presented with septic spondylodiskitis, calcaneus osteomyelitis, and hip-joint arthritis. all displayed either an upper respiratory tract infection or eczema during the month prior to their admission. laboratory findings included an elevated leukocyte count and an elevated erythrocyte sedimentation rate. standard radiogra ...19989764556
use of the bact/alert blood culture system for culture of sterile body fluids other than blood.studies have demonstrated that large-volume culture methods for sterile body fluids other than blood increase recovery compared to traditional plated-medium methods. bact/alert is a fully automated blood culture system for detecting bacteremia and fungemia. in this study, we compared culture in bact/alert standard aerobic and anaerobic bottles, bact/alert fan aerobic and fan anaerobic bottles, and culture on routine media for six specimen types, i.e., continuous ambulatory peritoneal dialysate ( ...19989774578
polymerase chain reaction diagnosis of kingella kingae arthritis in a young child. 19989827297
an assessment of the current diagnostic criteria for infective endocarditis.a firm diagnosis of infective endocarditis is difficult to establish. clinicians often face a decision-making dilemma about whether to treat a patient presenting with some features that suggest endocarditis. this article summarizes both the previous and the recently proposed criteria for the diagnosis of infective endocarditis, and reviews the efficacy of the new criteria. the authors also discuss the experience at the toronto hospital, toronto, ontario, with this disease, paying specific attent ...199822346546
infective endocarditis due to unusual or fastidious microorganisms.infective endocarditis due to fastidious microorganisms is commonly encountered in clinical practice. some organisms such as fungi account for up to 15% of cases of prosthetic valve infective endocarditis, whereas organisms of the hacek group (haemophilus parainfluenzae, h. aphrophilus, and h. paraphrophilus, actinobacillus actinomycetemcomitans, cardiobacterium hominis, eikenella corrodens, and kingella kingae) cause 3% of community-acquired cases of infective endocarditis. special techniques a ...19979179137
kingella kingae bacteremia in an immunocompetent adult host. 19979196226
use of the isolator 1.5 microbial tube for culture of synovial fluid from patients with septic arthritis.synovial fluid specimens obtained from patients with arthritis were plated onto solid media (conventional cultures) or inoculated into an isolator 1.5 microbial tube (isolator cultures), and the yield and time to detection of organisms were compared. overall, 144 specimens obtained from 137 patients were processed, and 31 (21.5%) cultures obtained from 29 patients were positive by at least one method. staphylococcus aureus was isolated from 12 patients, streptococcus pneumoniae and kingella king ...19979276427
kingella kingae endocarditis in a child with hair-cartilage hypoplasia.abstract. kingella kingae is a fastidious gram-negative rod that since the 1980s has been appreciated as a cause of a variety of human infections, including bone and joint infections, bacteremia, and rarely endocarditis [2, 6, 7, 9]. k. kingae endocarditis is rare, and only a few cases occur in normal, native valves. we report a case of k. kingae endocarditis in a patient with hair-cartilage hypoplasia who had previously undergone bone marrow transplantation. the combination of these rare condit ...19979326695
kingella kingae infections in paediatric patients: 5 cases of septic arthritis, osteomyelitis and bacteraemia.kingella kingae is a gram-negative rod most often recognized as 1 of the organisms causing septic arthritis and osteomyelitis in children. infection caused by k. kingae had not been diagnosed in iceland until 5 cases were diagnosed at the paediatric department at the university hospital of iceland over a 1 year period. in this report we describe these 5 children with invasive infection caused by k. kingae (2 with septic arthritis, 1 with osteomyelitis, 1 with septic arthritis and osteomyelitis, ...19979435039
kingella kingae endocarditis following chickenpox in infancy. 19979495681
kingella kingae: an emerging cause of invasive infections in young children.kingella kingae, a fastidious hemolytic gram-negative bacillus once considered to be an exceptional cause of disease, has emerged in recent years as an important invasive pathogen in children. when synovial fluid and other exudates were inoculated into blood culture bottles, enhanced recovery of the organism was observed, and an annual incidence of invasive k. kingae infections of 27.4 per 100,000 children younger than age 24 months was demonstrated in southern israel. skeletal infections are th ...19979142783
kingella kingae occult bacteremia in a toddler. 19968783365
respiratory carriage of kingella kingae among healthy children.the role of kingella kingae as an invasive pathogen of young children is being increasingly recognized, but the niche of the organism in the respiratory tract and its prevalence in the normal flora of children remain unknown. to investigate these two aspects throat and nasopharyngeal cultures were obtained every 2 weeks from two cohorts of children, ages 6 to 42 months on enrollment, attending a day-care center in southern israel. to determine the age-related prevalence of k. kingae, throat cult ...19958532424
growth differences of capnocytophaga canimorsus strains and some other fastidious organisms on various columbia-based blood agar media.three human isolates of capnocytophaga canimorsus from blood cultures showed no growth when cultivated on sheep blood agar plates based on bbl columbia agar base, whereas the same three strains grew excellently on sheep blood agar plates based on difco columbia agar bases no. 2 or eh. two of the three strains also grew well on blood agar plates based on biomérieux columbia agar. strains that grew better on either difco or biomérieux columbia based blood agar plates were found among eikenella cor ...19959810657
outpatient treatment of endocarditis in a clinic-based program in argentina.the major cost in the treatment of infective endocarditis (ie) is the length of hospitalization required for the administration of intravenous antibiotics. this can be reduced by substituting shorter regimens and by the introduction of outpatient parenteral antibiotic therapy (opat). careful selection of patients is vital for the success of opat in ie. the patients should be hemodynamically stable and without clinical complications. the delivery of opat for ie followed a clinical and home-based ...19957588859
evaluation of novel vancomycin-containing medium for primary isolation of kingella kingae from upper respiratory tract specimens.a new selective medium (bav), consisting of trypticase agar with 5% sheep hemoglobin and 2 micrograms of vancomycin per ml, was compared with the routine blood-agar medium for the primary isolation of kingella kingae from upper respiratory specimens from a population of young children. infection was detected by the bav medium in 43 of 44 (98%) cultures positive for k. kingae, and detection of the organism was facilitated by inhibition of gram-positive flora. infection was detected in only 10 of ...19957615773
epidemiology, etiology, and clinical features of septic arthritis in children younger than 24 months.to examine the incidence, etiology, and clinical features of septic arthritis in patients younger than 24 months.19957735407
kingella kingae bacteremia in children. 19947892088
a numerical phenotypic taxonomic study of the genus neisseria.a numerical phenotypic taxonomic study of 315 strains of neisseria and some allied bacteria examined for 155 phenotypic tests showed 31 groups, most of which were reasonably distinct. these fell into four major areas. areas a, b and c contained species of neisseria, whereas area d contained the organisms known as 'false neisserias' together with branhamella, moraxella and kingella species. area a contained n. gonorrhoeae (which showed two subgroups), n. meningitidis (with two subgroups, and n. c ...19948000550
in-vitro activity of beta-lactam and other antimicrobial agents against kingella kingae. 19948040128
eleven year review of infective endocarditis.twenty children were treated for infective endocarditis (ie) at our lady's hospital for sick children during an eleven year period from january 1980 to december 1990. one child had i.e. on two occasions due to different microorganisms. two had down syndrome. congenital heart disease (chd) was the single most common underlying condition and there was none with rheumatic heart disease. two had no clinically recognised cardiac anomaly. 13/20 (65%) had acyanotic heart disease and 5/20 (25%) had cyan ...19948056546
phylogenetic relationships between some members of the genera neisseria, acinetobacter, moraxella, and kingella based on partial 16s ribosomal dna sequence analysis.we obtained 16s ribosomal dna (rdna) sequence data for strains belonging to 11 species of proteobacteria, including the type strains of kingella kingae, neisseria lactamica, neisseria meningitidis, moraxella lacunata subsp. lacunata, [neisseria] ovis, moraxella catarrhalis, moraxella osloensis, [moraxella] phenylpyruvica, and acinetobacter lwoffii, as well as strains of neisseria subflava and acinetobacter calcoaceticus. the data in a distance matrix constructed by comparing the sequences suppor ...19947520730
kingella kingae septicaemia in association with hiv disease. 19948091526
clinical features and epidemiology of invasive kingella kingae infections in southern israel.to characterize the clinical spectrum and epidemiology of invasive kingella kingae infections in children living in southern israel.19938233740
septicemia due to beta-lactamase-positive kingella kingae. 19938268376
kingella kingae osteomyelitis of the calcaneus in young children. 19938345991
phylogeny of species in the family neisseriaceae isolated from human dental plaque and description of kingella oralis sp. nov [corrected].fourteen human periodontal isolates recovered from a purported eikenella corrodens-selective medium containing 1 microgram of clindamycin per ml displayed biochemical traits which differed from those described for e. corrodens. these organisms were gram-negative rods which corroded agar. the isolates were oxidase positive and urease, indole, and esculin negative. they differed from e. corrodens in catalase, nitrate reduction, lysine decarboxylase, and ornithine decarboxylase activities. one isol ...19938347509
relatedness of three species of "false neisseriae," neisseria caviae, neisseria cuniculi, and neisseria ovis, by dna-dna hybridizations and fatty acid analysis.dna-dna hybridization was used to determine the levels of genomic relatedness of the three species of "false neisseriae," neisseria caviae, neisseria cuniculi, and neisseria ovis. the reference strains of these species exhibited high levels of intraspecies relatedness (93 to 100% for n. caviae, 79 to 100% for n. cuniculi, and 68 to 100% for n. ovis) but low levels of interspecific relatedness (less than 34%) to each other and to various species belonging to the beta subclass of the proteobacteri ...19938494736
kingella kingae, a rare cause of bacterial meningitis.a male adolescent with a history of pharyngitis developed meningitis due to kingella kingae. this is a gram-negative coccobacillus belonging to the family of neisseriaceae. it is a rarely reported human pathogen, from which only 2 cases of meningitis have been described up to the present day. our patient developed ophthalmoplegia, suggestive of basal meningitis. he was treated with penicillin g and recovered completely.19921324818
isolation of kingella kingae from a corneal ulcer.kingella kingae was isolated from a corneal ulcer in an 11-month-old male. this organism has been previously reported from normally sterile sites, including sites of endophthalmitis, but this is the first time isolation from the cornea has been reported.19921401031
kingella kingae intervertebral diskitis in an adult.kingella kingae rarely causes infection and is mainly associated with endocarditis and septic arthritis in adults. the organism is also capable of causing intervertebral diskitis in children, but thus far, no reports of this infection occurring in adults have been published. a case of diskitis due to k. kingae in an adult is reported for the first time, and the literature on this infection in children is reviewed.19921520804
kingella kingae infection in children. 19921565566
high prevalence of kingella kingae in joint fluid from children with septic arthritis revealed by the bactec blood culture system.in an effort to improve detection of fastidious organisms, joint fluid aspirates of pediatric patients were inoculated into bactec 460 aerobic blood culture bottles, in addition to cultures on solid media. culture records for the 1988 to 1991 period were reviewed to compare the performance of both methods for the recovery of pathogens. overall, 216 children underwent a diagnostic joint tap, and 63 specimens grew significant organisms, including kingella kingae in 14. while both methods were comp ...19921583131
application of quadferm+ for the identification of fastidious gram-positive and gram-negative bacilli.the 2-hr quadferm+ kit (qf) (analytab products, plainview, ny) was compared with conventional tube tests for the identification of the hacek bacteria (haemophilus aphrophilus, actinobacillus actinomycetemcomitans, cardiobacterium hominis, eikenella corrodens, kingella kingae), other haemophilus and kingella spp., capnocytophaga, corynbacterium, and moraxella spp. test results were identical for 296 comparisons with 74 isolates (74%). in the remaining 104 comparisons for 26 isolates, 50 reactions ...19911873978
kingella kingae meningitis in an infant. 19911885909
osteoarticular infections due to kingella kingae in children.by the description of two cases of osteoarticular infections due to kingella kingae in two young children we wish to draw the attention of clinicians to invasive infections due to this micro-organism. since its biological characterization in 1976, k. kingae has been increasingly reported as a human pathogen. most common presentations are endocarditis, bacteraemia, septic arthritis, osteomyelitis and spondylodiscitis. interestingly, osteorticular involvement is largely predominant in previously h ...19911915510
kingella kingae infection in children: ten cases and a review of the literature. 19911923682
kingella kingae endophthalmitis in an infant.an 11-month-old girl presented with metastatic endophthalmitis. the causative organism was the gram-negative coccobacillus kingella kingae. this is an uncommon organism first recognised in 1967. it has never been previously reported to cause endophthalmitis, but is associated with at least four other infective syndromes in children. endophthalmitis is a potentially lethal and sight-threatening disease. kingella kingae is primarily a paediatric pathogen which fortunately responds well to antibiot ...19911958367
kingella kingae dactylitis in an infant. 19912002223
kingella kingae intervertebral disk infection.disk inflammation in children is believed to result from infection, and staphylococcus aureus is reported to be the organism most commonly isolated from cases of intervertebral disk infection. a case of disk inflammation caused by the unusual pathogen kingella kingae is described. the antibiotic susceptibility of other k. kingae isolates and the clinical features of 11 other previously reported cases of disk infection caused by this microorganism are reviewed.19912056049
polymicrobic septic arthritis caused by kingella kingae and enterococcus. 19902308886
[cervical spondylodiscitis caused by kingella kingae. apropos of a case].we report a new case of spondylodiscitis due to kingella kingae in a 19-month-old infant who had torticollis as the first manifestation. the main characteristics of kingella kingae infections are reviewed: frequency of ent and joint localizations, slow course, difficult clinical and bacteriological diagnosis, and satisfactory susceptibility to antimicrobial agents.19902350142
infections caused by moraxella, moraxella urethralis, moraxella-like groups m-5 and m-6, and kingella kingae in the united states, 1953-1980.from 1953 to 1980 the centers for disease control received 933 isolates of bacteria belonging to species of the genus moraxella, moraxella-like moraxella urethralis, now renamed oligella urethralis, unnamed groups m-5 and m-6, and kingella kingae. ordinarily sterile sites were the source of 233 isolates. moraxella nonliquefaciens, the most common isolate (356 strains), was recovered from upper respiratory or ocular sites in 208 (58%) of the cases. moraxella osloensis was next most common (199 st ...19902359906
[the isolation of kingella kingae by hemoculture must always suggest the diagnosis of endocarditis]. 19892529496
kingella kingae endocarditis in a patient with the acquired immunodeficiency syndrome. 19892603424
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