Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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sequence analysis of new tuf molecular types of 'candidatus phytoplasma solani' in iranian vineyards. | grapevine bois noir (bn) is caused by 'candidatus phytoplasma solani' ('ca. p. solani') and is one of the most important phytoplasma diseases in the euro-mediterranean viticultural areas. the epidemiology of bn can include grapevine as a plant host and is usually transmitted via sap-sucking insects that inhabit herbaceous host plants. tracking the spread of 'ca. p. solani' strains is of great help for the identification of plant reservoirs and insect vectors involved in local bn outbreaks. the m ... | 2020 | 32599831 |
primary and metastatic intracranial ewing sarcoma at diagnosis: retrospective international study and systematic review. | intracranial ewing sarcoma (ews) is rare and publications on primary or metastatic intracranial ews are minimal. the aim of this study was to describe incidence, clinical behavior, treatment, and factors associated with outcome in patients with primary intracranial ews or patients with a primary extracranial ews and cerebral metastases at diagnosis. we reviewed all patients with primary or with metastatic intracranial ews at diagnosis registered in the international clinical trial euro-e.w.i.n.g ... | 2020 | 32599807 |
reconfiguring health knowledges? contemporary modes of self-care as 'everyday fringe medicine'. | the contestation of expertise is perhaps nowhere more pronounced than in the field of health and well-being, on which this article focuses. a multitude of practices and communities that stand in contentious relationships with established forms of medical expertise and promote personalised modes of self-care have proliferated across euro-american societies. drawing on multi-sited ethnography in three domains - body-mind-spirit therapies, vaccine hesitancy and consumer-grade digital self-tracking ... | 2020 | 32597366 |
the game of science and puzzles of paradigm. | zagaria, andó́ and zennaro (in this issue) have offered that the discipline of psychology is fraught with conceptual chaos and a multiplicity of constructs. they have also assessed psychology to be a soft science, with much potential to be a hard science, should it allow itself to be unified by the principles offered by evolutionary psychology. with this approach, psychology would transition from its pre-paradigmatic to a paradigmatic status. in this commentary, we question their premise, method ... | 2020 | 32596801 |
long-term periodontitis treatment costs according to the 2018 classification of periodontal diseases. | to assess if long-term treatment costs in periodontitis patients differ between stage iii vs. iv and grade b vs. c according to the 2018 classification of periodontal diseases. | 2020 | 32592828 |
efficacy of combined antigravity treadmill and conventional rehabilitation after hip fracture in patients with sarcopenia. | to compare long-term effects of antigravity treadmill (agt) combined with conventional rehabilitation (cr) and cr after hip fracture in patients with sarcopenia. | 2020 | 32592578 |
a probiotic-based sanitation system for the reduction of healthcare associated infections and antimicrobial resistances: a budget impact analysis. | healthcare associated infections (hais) and antibiotic resistance have high social and economic burdens. healthcare environments play an important role in the transmission of hais. the probiotic cleaning hygiene system (pchs) has been shown to decrease hospital surface pathogens up to 90% vs. conventional chemical cleaning (ccc). this study compares pchs to ccc as to reduction of hais and their severity, related antibiotic resistances, and costs. incidence rates of hais/antibiotic resistances we ... | 2020 | 32585922 |
authors' correction for euro surveill. 2020;25(23). | 2020 | 32583763 | |
post-dieselgate: evidence of nox emission reductions using on-road remote sensing. | the dieselgate scandal which broke in september 2015 demonstrated that vehicle manufacturers, such as the volkswagen group (vwg), engaged in software-based manipulation which led to vehicles passing laboratory-based emission testing limits but were far more polluting while being driven on roads. using 23 000 on-road remote sensing measurements of light-duty euro 5 diesel vehicles in the united kingdom between 2012 and 2018, vwg vehicles with the "dieselgate-affected" ea189 engine demonstrated an ... | 2020 | 32582808 |
the impact of internet usage and knowledge-intensive activities on households' healthcare expenditures. | this paper examines the impact of the internet usage and knowledge intensive activities on households' healthcare expenditures similarly, the paper aims to recognize and understand, from a value-creation perspective, the correlation between: internet access of households (ia), individuals frequently using the internet (iu), individuals searching on internet for health-related information (hi), payments made by households for healthcare (phh), expressed as euro per inhabitant and employment in kn ... | 2020 | 32580302 |
the introduction of a third cdk4/6 inhibitor does not change the cost-effectiveness profile in first and subsequent-lines after progression or relapse during previous endocrine therapy in patients with hormone receptor positive (hr+)/human epidermal receptor-2 negative (her-2) advanced or metastatic breast cancer. | the aim of this study was to assess the pharmacological costs of cdk4/6-inhibitors (palbociclib, ribociclib and abemaciclib) in hormone receptor positive (hr+)/human epidermal receptor 2-negative (her2-) advanced or metastatic breast cancer (bc). we have considered pivotal phase iii randomized controlled trials (rcts) of palbociclib, ribociclib and abemaciclib for the treatment of postmenopausal women with hr+/her2- advanced or metastatic bc in first-line in association with letrozole or anastro ... | 2020 | 32576084 |
[optimization of the "pharmaceutical consultation" practiced by pharmacists - review, feedback and future proposals for development since the introduction of the initiative in 2013 focusing on the calvados area]. | in 2012, a national agreement of pharmacists was initiated in france and then amended in 2013 to introduce the "pharmaceutical consultation". these consultations must be conducted by the pharmacist with the patient in a confidential area in pharmacy or patient residence. the objective is to decrease the frequency of negative side effects of the medical treatments (anti-vitamins k, direct oral anticoagulants and inhaled corticoid) and to improve the correct use of medication therefore assure the ... | 2020 | 32574569 |
disparities of indoor temperature in winter: a cross-sectional analysis of the nationwide smart wellness housing survey in japan. | the who housing and health guidelines recommend a minimum indoor temperature of 18°c to prevent cold-related diseases. in japan, indoor temperatures appear lower than in euro-american countries because of low insulation standards and use of partial intermittent heating. this study investigated the actual status of indoor temperatures in japan and the common characteristics of residents who live in cold homes. we conducted a nationwide real-world survey on indoor temperature for 2 weeks in winter ... | 2020 | 32573794 |
"changing the narrative": a study on professional identity formation among black/african american physicians in the u.s. | professional identity formation (pif) is considered a key process in physician development. however, early pif research may have inadvertently left out experiences from ethnically/racially minoritized physicians. as a result, the pif literature may have forwarded dominant perspectives and assumptions about pif that does not reflect those of minoritized physicians. this study used a cross-sectional study design, in which interview data was initially collected using constructivist grounded theory ... | 2020 | 32572728 |
risk factors for mortality in acute aortic dissection type a: a centre experience over 15 years. | acute aortic dissection type a (aada) is still associated with a high mortality rate and frequent postoperative complications. this study was designed to evaluate the risk factors for mortality in aada patients. | 2020 | 32559807 |
autopsy registry can facilitate covid-19 research. | the who declared the global outbreak of sars-cov-2 a pandemic on march 11, 2020, and "call(ed) on all countries to exchange country experiences and practices in a transparent and timely way" (http://www.euro.who.int/en/health-topics/health-emergencies/pages/news/news/2020/03/who-announces-covid-19-outbreak-a-pandemic). to date, many medical societies have announced their intention to collect and analyze data from covid-19 patients and some large-scale prospective data collections are already run ... | 2020 | 32559338 |
the euro heart survey and eurobservational research programme (eorp) in atrial fibrillation registries: contribution to epidemiology, clinical management and therapy of atrial fibrillation patients over the last 20 years. | management of atrial fibrillation (af) may be challenging in clinical practice. given the complexity of af patients and the continuous advances in af clinical management, there is a need for standardized programmes aimed at collecting so-called 'real-world clinical practice data' regarding the epidemiology, diagnostic/therapeutic/management practices and assessing adherence to guidelines. over the past 20 years, the number of registries and surveys based on real-world af patients has been dramat ... | 2020 | 32557091 |
spatial pattern of bois noir: case study of a delicate balance between disease progression and recovery. | bois noir (bn) is the most important phytoplasma disease of euro-mediterranean area and induces severe loss of production and even the death of vines. understanding the delicate balance between disease progression and recovery of bn infected plants over space and time is crucial to set up management tools. the data collected and analysed allowed to provide insights into dispersal pattern of the disease, caused by'candidatus phytoplasma solani'. point pattern analysis (ppa) was applied to assess ... | 2020 | 32555207 |
economic analysis of brief motivational intervention following trauma related to drugs and alcohol. | very few studies have conducted an economic assessment of brief motivational intervention (bmi) in patients experiencing traumatic injuries related to alcohol and/or substance use. furthermore, findings concerning the potential long-term economic benefits of bmi applied in nursing are promising but very scarce. | 2020 | 32555008 |
particulate emissions of a modern diesel passenger car under laboratory and real-world transient driving conditions. | exhaust emissions from diesel vehicles are significant sources of air pollution. in this study, particle number emissions and size distributions of a modern euro 5b -compliant diesel passenger car exhaust were measured under the nedc and us06 standard cycles as well as during different transient driving cycles. the measurements were conducted on a chassis dynamometer; in addition, the transient cycles were repeated on-road by a chase method. since the diesel particulate filter (dpf) removed prac ... | 2020 | 32554088 |
proposal for a en 149 acceptable reprocessing method for ffp2 respirators in times of severe shortage. | transmission of sars-cov-2 to health care workers (hcw) poses a major burden in the current covid-19 pandemic. unprotected exposure to a covid-19 patient is a key risk factor for hcws. transmission mainly occurs by droplet transmission, or by aerosol generating procedures. respirators such as filtering face piece masks (ffp2), also called respirators, are required to prevent transmission during aerosol generating procedures, as part of the personal protective equipment (ppe) for hcws. however, m ... | 2020 | 32552867 |
impact of different geriatric conditions on choice of therapy and in-hospital outcomes in elderly patients with acute coronary syndrome. | the clinical benefit of invasive therapy in elderly patients with acute coronary syndrome (acs) remains unclear. furthermore, the decision-making process to treat this growing patient group is also debatable. the purpose of this study was to assess the association between elderly acs patients, the treatment choice and their in-hospital outcomes after non-st-elevation (nste)-acs in a consecutive series of patients >75 years of age. | 2020 | 32546990 |
cost-utility analysis of antibiotic treatment in patients with chronic low back pain and modic changes: results from a randomised, placebo-controlled trial in norway (the aim study). | to evaluate the cost-utility of 100 days of antibiotics in patients with chronic low back pain (lbp) and type i or ii modic changes included in the antibiotic treatment in patients with chronic low back pain and modic changes (aim) study. | 2020 | 32546490 |
deconstructing earth's oldest ichnofossil record from the pilbara craton, west australia: implications for seeking life in the archean subseafloor. | microtextures of titanite (catisio5 ) in exceptionally preserved archean pillow lavas have been proposed as the earliest examples of microbial ichnofossils. an origin from microbial tunneling of seafloor volcanic glass that is subsequently chloritized and the tunnels infilled by titanite has been argued to record the activities of subseafloor microbes. we investigate the evidence in pillow lavas of the 3.35 ga euro basalt from the pilbara craton, western australia, to evaluate the biogenicity of ... | 2020 | 32542902 |
ultrasonographic measurement of talar cartilage thickness in patient with cerebral palsy. | foot deformities are one of the most common musculoskeletal problems in children with cerebral palsy (cp). these deformities affect the walking ability and function of the patients. talar cartilage is the hyaline joint cartilage of the tibiotalar joint which plantarflexes and dorsiflexes of the ankle. the aim of this study was to determine whether talar cartilage thickness was affected in children with ambulant diplegic cerebral palsy. | 2020 | 32541350 |
decades of tight fiscal policy have left the health care system in italy ill-prepared to fight the covid-19 outbreak. | although austerity was particularly strong in the aftermath of the economic crisis of 2008 and its consequences in the euro area, italian fiscal policies have been characterised by tough consolidation periods ever since the 1990s. | 2020 | 32536710 |
[the gambling industry: a public health perspective.] | gambling may cause a variety of problems, both health and social, to the player, his family and his environment; problems can be more serious for those who gamble more frequently or bet more money. beyond the mental health gambling disorder and considering other harms derived from gambling, it is possible to develop a public health approach to the issue, including both prevention and harm reduction aspects. in recent decades gambling availability has expanded, with attempts at regulation. the ob ... | 2020 | 32536686 |
community acquired pneumonia: a cost-of-illness analysis in greece. | community acquired pneumonia (cap) is an acute respiratory infection with high clinical and economic burden, especially when hospitalisation is required. the present study aimed to assess the mean direct cost per cap outpatient and inpatient care in greece, in the absence of previous estimates. | 2020 | 32536183 |
cost of decentralized car t-cell production in an academic nonprofit setting. | chimeric antigen receptor (car) t-cell therapy is a promising immunotherapy with high acquisition costs, and it has raised concerns about affordability and sustainability in many countries. furthermore, the current centralized production paradigm for the t cells is less than satisfactory. therefore, several countries are exploring alternative t-cell production modes. our study is based on the t-cell production experience in a nonprofit setting in germany. we first identified the work steps and m ... | 2020 | 32535920 |
trends in drug costs and overall survival in patients with metastatic non-small cell lung cancer in the netherlands diagnosed from 2008 through 2014. | the value-based health care concept defines patient value as patient-relevant outcomes divided by costs. the aim of the present study was to assess the development of systemic treatment costs over the years compared with changes in overall survival (os) at the level of a diagnosis of stage iv non-small cell lung cancer (nsclc). | 2020 | 32533521 |
on-road detection of trucks with high nox emissions from a patrol vehicle with on-board ftir analyzer. | technological advances in heavy-duty vehicle engines, allowing them to reach nox emissions comparable to european diesel passenger cars per km driven, are being compromised by aftermarket defeat devices such as selective catalytic reduction (scr) emulators, many of which can be quickly deactivated by the driver. in a pilot study, the prevalence of trucks with excess nox emissions on czech motorways was evaluated using an ordinary customs administration patrol vehicle temporarily fitted with a po ... | 2020 | 32531593 |
author's correction for euro surveill. 2020;25(10). | 2020 | 32524952 | |
analysis of monitoring data where butterflies fly year-round. | butterfly monitoring schemes (bmss) engage the public in conservation and provide data sets that cover broad geographical areas over long timescales. most existing bmss are in temperate climates; however, the israeli butterfly monitoring scheme (bms-il), established in 2009, is a notable exception as it encompasses a large climatic gradient from euro-siberian through mediterranean to hyper-arid regions. israel's climate poses challenges in analyzing data from year-round butterfly activity, as in ... | 2020 | 32524681 |
low-value care practice in headache: a spanish mixed methods research study. | headache is one of the most prevalent diseases. the global burden of disease study ranks it as the seventh most common disease overall and the second largest neurological cause of disability in the world. the "do not do" recommendations are a strategy for increasing the quality of care and reducing the cost of care for headache. this study aimed to identify specific low-value practices in headache care, determine their frequency, and estimate the cost overrun that they represent, in order to est ... | 2020 | 32522142 |
impact of dominant symptom on 12-month patient-reported outcomes for patients undergoing lumbar spine surgery. | the impact of symptom characteristics on outcomes of spine surgery remains elusive. | 2020 | 32521016 |
cost-effectiveness of coronary and peripheral artery disease antithrombotic treatments in finland. | currently, 15-20% of individuals with coronary artery disease (chronic coronary syndrome [ccs]) or peripheral artery disease (pad) receiving routine treatment experience cardiovascular events (cves) within 3-4 years. using picosteps (patients-intervention-comparators-outcomes-setting-time-effects-perspective-sensitivity analysis) reporting, we evaluated the cost-effectiveness of recently approved rivaroxaban 2.5 mg twice daily in combination with acetylsalicylic acid 100 mg daily (riv + asa) for ... | 2020 | 32519113 |
establishment of a guided, in vivo, multi-channel, abdominal, tissue imaging approach. | novel tools in humane animal research should benefit the animal as well as the experimentally obtained data. imaging technologies have proven to be versatile and also in accordance with the demands of the 3 r principle. however, most imaging technologies are either limited by the target organs, number of repetitive imaging sessions, or the maximal resolution. we present a technique-, which enables multicolor abdominal imaging on a tissue level. it is based on a small imaging fiber endoscope, whi ... | 2020 | 32513950 |
virtual education: dental morphologies in a virtual teaching environment. | digital technology is already playing an increasingly important role in the education of students. the present investigation examined the acceptance of preclinical students for learning dental morphologies in virtual reality (vr). | 2020 | 32511757 |
indirect costs of myocardial infarction in portugal. | cardiovascular disease, and particularly myocardial infarction (mi), carries a significant economic burden, through productivity losses (indirect costs) associated with temporary absence from work, that has not yet been adequately studied in portugal. our objective was to quantify the indirect costs of mi in the first year after admission. | 2020 | 32505635 |
infective endocarditis in the netherlands: current epidemiological profile and mortality : an analysis based on partial esc eorp collected data. | infective endocarditis (ie) is associated with a high in-hospital and long term mortality. although progress has been made in diagnostic approach and management of ie, morbidity and mortality of ie remain high. in the latest european guidelines, the importance of the multi-modality imaging in diagnosis and follow up of ie is emphasized. | 2020 | 32504340 |
acute toxicity related to misuse (nonmedical use) of tramadol: experience of the european drug emergencies network plus. | following the development of the tramadol crisis currently affecting countries in the middle east, and africa, there has been increasing international interest in the regulation of tramadol. this study investigates the misuse of tramadol in patients presenting to emergency departments across europe. data from 32 emergency departments in 21 countries were extracted from the euro-den plus database for the 4-year period from 1 january 2014 to 31 december 2017. of the reported 24,957 emergency depar ... | 2020 | 32503085 |
a comparison of chemo-free strategy with g-csf plus plerixafor on demand versus intermediate-dose cyclophosphamide and g-csf as pbsc mobilization in newly diagnosed multiple myeloma patients: an italian explorative cost analysis. | upfront single or tandem asct still represents an integral part of treatment for patients with multiple myeloma. the combination of intermediate dose (id) - cyclophosphamide plus g-csf, has been considered the standard method as mobilization regimen. no prospective randomized clinical trials have compared efficacy and costs using id - cyclophosphamide against a chemo-free mobilization strategy with g-csf and plerixafor on demand. | 2020 | 32499108 |
fifteen years of a nationwide culture collection of neisseria gonorrhoeae antimicrobial resistance in portugal. | neisseria gonorrhoeae antimicrobial resistance (amr) and gonorrhea disease burden remain major public health concerns worldwide. to contribute to the supranational demands to monitor and manage the spread of antimicrobial-resistant n. gonorrhoeae, the portuguese nih promoted the creation of the national laboratory network for neisseria gonorrhoeae collection (ptgononet). the present study reports the n. gonorrhoeae major amr trends observed from 2003 up to 2018. all isolates described in the pre ... | 2020 | 32494956 |
brain activity and connectivity differences in reward value discrimination during effort computation in schizophrenia. | negative symptoms in the motivational domain are strongly correlated with deficits in social and occupational functioning in schizophrenia. however, the neural substrates underlying these symptoms remain largely unknown. twenty-eight adults with schizophrenia and twenty healthy volunteers underwent functional magnetic resonance while completing a lottery game designed to capture reward-related cognitive processes. each trial demanded an initial investment of effort in form of key presses to incr ... | 2020 | 32494887 |
are our babies off to a healthy start? the state of implementation of the global strategy for infant and young child feeding in europe. | to protect children's right to optimal nutrition, who/unicef developed a global strategy for infant and young child feeding, endorsed by all 53 who/euro member states. the world breastfeeding trends initiative (wbti) is a tool for monitoring implementation of the global strategy. it comprises 15 indicators, ten referring to policies and programmes, and five to feeding practices. each is scored on a scale of 10, giving a total score of 150 for global strategy implementation. to date, 18 who/euro ... | 2020 | 32493416 |
improved diagnostic policy for respiratory tract infections essential for patient management in the emergency department. | aim: establishing an optimal diagnostic policy for patients with respiratory tract infections, at the emergency department (ed) of a university hospital in the netherlands. methods: adult patients were sampled at admission, during the respiratory season (2014-2015). the filmarray-rp was implemented at the clinical virology laboratory. diagnostics were provided from 8 am to 10 pm, weekends included. results: 436/492 (89%) results were available while patients were still at the ed. median tat from ... | 2020 | 32490688 |
the second euro-asian congress of pharmacoepidemiology recently held in tehran 2019. | 2020 | 32489953 | |
occupational medicine and environmental health in the border areas of euro-arctic barents region: a review of 30-year russian-norwegian research collaboration outcomes. | this year marks 30 years of close collaboration between a consortium of institutions, namely, the northwest public health research center, saint-petersburg (nwphrc); the institute of community medicine (icm) of uit (the arctic university of norway, tromsø); the national institute of occupational health (nioh), oslo; the university hospital of northern norway (unn) at tromsø; and mcmaster university (mu), hamilton, on, canada. during the early years of cooperation, dr. chashchin was the director ... | 2020 | 32486198 |
impacts of climate change on reservoir water availability, quality and irrigation needs in a water scarce mediterranean region (southern portugal). | future climate for the mediterranean climatic region is expected to bring an increase in temperatures, decrease in the precipitation quantity and shifts in the seasonal precipitation pattern. although the impacts of climate change on water resources have been relatively well explored for the mediterranean climatic region, the specific consequences for reservoirs and, in particular, water availability and irrigation issues have been less studied. the objective of this work is two-fold: (i) to ass ... | 2020 | 32485369 |
hospitalization direct cost of adults with community-acquired pneumonia in portugal from 2000 to 2009. | hospitalizations due to community-acquired pneumonia (cap) in mainland portugal from 2000 to 2009 accounted for 3.7% of all hospital admissions in population with 18 or more years of age. there is no direct-cost data regarding these admissions. | 2020 | 32482604 |
secukinumab shows high and sustained efficacy in nail psoriasis: 2.5-year results from the randomized placebo-controlled transfigure study. | secukinumab, a fully human monoclonal antibody that selectively neutralises interleukin-17a, a cornerstone cytokine in psoriasis, has shown long-lasting efficacy and safety in the complete spectrum of psoriasis manifestations. | 2020 | 32479641 |
genetic variability of blood groups in southern brazil. | we evaluated genetic variability among the blood groups kell (c.578c > t and c.1790t > c), kidd (c.838a > g), duffy (c.125a > g, c.265c > t and c.1-67t > c), diego (c.2561c > t), mns (c.143t > c) and rh (c.676g > c) in rio grande do sul in southern brazil. genetic profiling from 382 volunteer blood donors was performed through allelic discrimination assays using a hydrolysis probe (taqman®) with a real-time pcr system. the sample was divided into two groups: euro-brazilian and afro-brazilian. a ... | 2020 | 32478792 |
prevalence of cochlear implants in europe: trend between 2010 and 2016. | objective: to collect figures on the numbers of children and adults receiving cochlear implants across europe, compare the figures for 2016 with those for 2010, and identify any trends. materials and methods: in 2018 euro-ciu invited their 23 member countries to conduct a survey collecting data on the number of ci recipients in 2016 and 2017. data were received from 15 countries, representing more than 100 000 ci recipients in europe. results: for paediatric ci, there was an increase in nearly a ... | 2020 | 32476613 |
action seniors! cost-effectiveness analysis of a secondary falls prevention strategy among community-dwelling older fallers. | the otago exercise program (oep) has demonstrated cost-effectiveness for the primary prevention of falls in a general community setting. the cost-effectiveness of exercise as a secondary falls prevention (ie, preventing falls among those who have already fallen) strategy remains unknown. the primary objective was to estimate the cost-effectiveness (incremental cost-effectiveness/utility ratio) of the oep from a healthcare system perspective. | 2020 | 32472567 |
future heat waves over the mediterranean from an euro-cordex regional climate model ensemble. | heat waves are among the most relevant extreme climatic events due to their effects on society, agriculture and environment. the aim of this work is to improve our understanding of heat waves over the mediterranean basin during the 21st century from an ensemble of regional climate models (rcms). focus has been placed on sensitivities to forcing global models, emissions scenarios and the rcm resolution, being the first work based on euro-cordex simulations to fully analyze future heat waves in th ... | 2020 | 32472098 |
simulating automated emergency braking with and without torricelli vacuum emergency braking for cyclists: effect of brake deceleration and sensor field-of-view on accidents, injuries and fatalities. | this study estimates how many additional cyclist accidents, injuries or fatalities are avoided or mitigated by adding a system which increases braking levels, the torricelli vacuum emergency brake (veb), to a state-of-the-art automated emergency braking (aeb) system. to obtain a realistic state-of-the-art aeb system, the aeb parameter settings were defined to fulfil but not exceed the performance necessary to achieve a full score in the european new car assessment program (euro ncap). the system ... | 2020 | 32470821 |
the purchase of the diabetic healthy food basket in cyprus results in cost savings: is it affordable among the low-income population? | the main objective was to assess the cost, acceptability and affordability of the cypriot diabetic healthy food basket (dhfb). | 2020 | 32466821 |
real-world assessment of vehicle air pollutant emissions subset by vehicle type, fuel and euro class: new findings from the recent uk edar field campaigns, and implications for emissions restricted zones. | this paper reports upon and analyses vehicle emissions measured by the emissions detecting and reporting (edar) system, a vehicle emissions remote sensing system (verss) type device, used in five uk based field campaigns in 2016 and 2017. in total 94,940 measurements were made of 75,622 individual vehicles during the five campaigns. the measurements are subset into vehicle type (bus, car, hgv, minibus, motorcycle, other, plant, taxi, van, and unknown), fuel type for car (petrol and diesel), and ... | 2020 | 32464378 |
vaccination is a suitable tool in the control of aujeszky's disease outbreaks in pigs using a population dynamics p systems model. | aujeszky's disease is one of the main pig viral diseases and results in considerable economic losses in the pork production industry. the disease can be controlled using preventive measures such as improved stock management and vaccination throughout the pig-rearing period. we developed a stochastic model based on population dynamics p systems (pdp) models for a standard pig production system to differentiate between the effects of pig farm management regimes and vaccination strategies on the co ... | 2020 | 32456342 |
[loans from the european stability mechanism to combat the corona crisis are not enough]. | on 9 april 2020, the euro area finance ministers agreed on credit lines with the european stability mechanism (esm) to counter the corona crisis. the esm loans are estimated at 200 billion euros. however, this figure is misleading. only a few states would benefit at all over a 10-year government bond in their own country. moreover, the scope of esm loans is limited. | 2020 | 32454546 |
real world fuel consumption prediction via a combined experimental and modeling technique. | this study investigates the possibility to evaluate real-world fuel consumption and co2 emissions based on a simulation approach and usage of generic vehicle simulation models, calibrated on the basis of experimental data recorded during on-road tests. a methodology for the development, calibration and validation of the models is described and the proposed simulation approach is applied on three euro 6 vehicles, one diesel, one gasoline and one plug-in hybrid vehicle. the validation of the devel ... | 2020 | 32454332 |
cost-minimization analysis of individually tailored or fixed-scheduled rituximab maintenance therapy for antineutrophil-cytoplasm antibody associated vasculitides. | patients included in mainritsan2 trial received either an individually tailored or a fixed-schedule therapy with rituximab as maintenance treatment of antineutrophil cytoplasm antibody associated vasculitides. the aim of this study was to compare the real-world costs of both arms. | 2020 | 32452315 |
setting maximum levels for lead in game meat in ec regulations: an adjunct to replacement of lead ammunition. | each year, hunters from 12 of the 27 european union (eu) countries and the uk shoot over 6 million large game mammals, 12 million rabbits and hares and over 80 million birds. they support an international game meat market worth over 1.1 thousand million euros. animals shot with lead ammunition frequently contain lead fragments in the carcass which contaminate meals made from game meat with concentrations of lead substantially above the maximum allowable level (ml) set by european commission regu ... | 2020 | 32451970 |
burden of hodgkin and non-hodgkin lymphoma in spain over a 10-year period: productivity losses due to premature mortality. | cancer is annually responsible for millions of deaths in europe and billions of euros in productivity losses; the estimated mortality rate of lymphoma was of 7.07 per 100,000 individuals in spain in 2018. this study aimed to evaluate the burden that lymphoma mortality represents for the spanish society. | 2020 | 32450710 |
[data sharing policies of clinical trials funders in france]. | the aims of this survey were to evaluate the percentage of french clinical trial funders with a data sharing policy, to describe their data sharing policies and, more generally, the transparency of the research they fund. | 2020 | 32446662 |
economic costs incurred by the patients with multiple sclerosis at different levels of the disease: a cross-sectional study in northwest iran. | multiple sclerosis (ms) causes significant economic burden to the patients, families, health systems and society. this study aimed to estimate the annual economic costs incurred by patients with multiple sclerosis (pwms) at different levels of the disease. | 2020 | 32446303 |
adolescent social withdrawal, parental psychological control, and parental knowledge across seven years: a developmental cascade model. | social withdrawal can be problematic for adolescents, increasing the risk of poor self-efficacy, self-esteem, and academic achievement, and increased levels of depression and anxiety. this prospective study follows students across adolescence, investigating links between social withdrawal and two types of parenting hypothesized to impact or be reactive to changes in social withdrawal. | 2020 | 32446111 |
health and economic consequences of applying the united states' pm2.5 automobile emission standards to other nations: a case study of france and italy. | the us has among the world's strictest automobile emission standards, but it is now loosening them. it is unclear where a nation should draw the line between the associated cost burden imposed by regulations and the broader societal benefits associated with having cleaner air. our study examines the health benefits and cost-effectiveness of introducing stricter vehicle emission standards in france and italy. | 2020 | 32445933 |
guided internet-based cognitive behavioral therapy in japanese patients with obsessive-compulsive disorder: protocol for a randomized controlled trial. | cognitive behavioral therapy for obsessive-compulsive disorder has been established, but access to this therapy in japan is limited. internet-based cognitive behavioral therapy may improve treatment accessibility and sufficiently improve obsessive-compulsive symptoms. there are few randomized controlled trials examining the effectiveness of internet-based cognitive behavioral therapy in patients with obsessive-compulsive disorder. we designed a randomized controlled trial protocol to assess the ... | 2020 | 32442142 |
genomic history of the italian population recapitulates key evolutionary dynamics of both continental and southern europeans. | the cline of human genetic diversity observable across europe is recapitulated at a micro-geographic scale by variation within the italian population. besides resulting from extensive gene flow, this might be ascribable also to local adaptations to diverse ecological contexts evolved by people who anciently spread along the italian peninsula. dissecting the evolutionary history of the ancestors of present-day italians may thus improve the understanding of demographic and biological processes tha ... | 2020 | 32438927 |
linked work lives: the interrelation of own and partner's employment history and their relationship with mental health in older european couples. | there is strong evidence for the importance of previous employment for mental health at older age but little is known about the role of partner's employment history in this. life course theory suggests that individual trajectories are linked and evidence from cross-sectional studies suggest that there are cross-over effects within couples. therefore, the present study tests the interdependence of own and partner's employment history and their relationship with depressive symptoms. | 2020 | 32438218 |
long-term outcomes of lupus nephritis treated with regimens based on cyclophosphamide and mycophenolate mofetil. | lupus nephritis (ln) has a considerable impact on the morbidity and mortality of systemic lupus erythematosus (sle) patients. long-term comparative outcome data from the indian subcontinent on treatment regimens with cyclophosphamide (cyp) and mycophenolate mofetil (mmf) are sparse. we assessed renal and patient survival for these patients in terms of the types of induction - cyp or mmf - and the two maintenance therapies - mmf or azathioprine (aza). | 2020 | 32437258 |
the economic burden of prostate cancer - a swedish prevalence-based register study. | incidence and prevalence of prostate cancer in sweden have increased markedly due to prostate-specific antigen (psa) testing. moreover, new diagnostic tests and treatment technologies are expected to further increase the overall costs. our aims were (i) to estimate the societal costs for existing testing, diagnosis, management and treatment of prostate cancer, and (ii) to provide reference values for future cost-effectiveness analyses of prostate cancer screening and treatment. | 2020 | 32434566 |
cost-effectiveness analysis of pretreatment screening for nudt15 defective alleles. | nucleotide triphosphate diphosphatase (nudt15) genetic testing in addition to thiopurine methyl transferase (tpmt) is recommended to reduce the incidence of adverse severe myelotoxicity episodes induced by thiopurines. | 2020 | 32433339 |
authors' correction for euro surveill. 2020;25(17). | 2020 | 32431292 | |
impact of environmental factors and physical activity on disability and quality of life in cidp. | a few observational studies and randomized trials suggest that exercise and rehabilitation may improve activity limitation and quality of life (qol) in patients with chronic inflammatory demyelinating polyradiculoneuropathy (cidp), but the impact of other modifiable factors on the severity of the disease is not well understood. using a structured questionnaire, we collected data on lifestyle and dietary habits of the patients included in the italian cidp database to investigate the possible infl ... | 2020 | 32430573 |
endovascular versus surgical creation of arteriovenous fistula in hemodialysis patients: cost-effectiveness and budget impact analyses. | the aim of the present study was to perform cost-effectiveness and budget impact analyses comparing endovascular arteriovenous fistula creation to surgical arteriovenous fistula creation in hemodialysis patients from the national healthcare service (nhs) perspective in italy. | 2020 | 32425096 |
the politicization of the european central bank: what is it, and how to study it? | the politicization of the european central bank (ecb) is a recurrent theme in debates on the eu after the crisis, yet it is one that still suffers from a considerable degree of vagueness. this is unfortunate as it hinders the development of useful discussions on the place and legitimacy of the ecb within europe's institutional order. to tackle this problem, this article presents a systematic analysis of the concept of ecb politicization and an agenda for future research on this phenomenon. after ... | 2020 | 32421056 |
preventing nosocomial infections in resource-limited settings: an interventional approach in healthcare facilities in burkina faso. | nosocomial pathogens are transmitted by contamination of surfaces causing healthcare-associated infections (hai). the impact of locally produced disinfectant with operational training as a means to improve hygiene in resource-limited healthcare facilities and prevent hai was evaluated. | 2020 | 32417112 |
early cardiac rehabilitation: could it improve functional outcomes and reduce length of stay and sanitary costs in patients aged 75 years or older? a retrospective case-control study. | cardiac rehabilitation (cr) is considered as a cornerstone in improving physical function in older people after cardiac procedures; however, its effects in patients aged more than 75 years are still debated. | 2020 | 32415667 |
what does cell therapy manufacturing cost? a framework and methodology to facilitate academic and other small-scale cell therapy manufacturing costings. | recent technical and clinical advances with cell-based therapies (cbts) hold great promise in the treatment of patients with rare diseases and those with high unmet medical need. currently the majority of cbts are developed and manufactured in specialized academic facilities. due to small scale, unique characteristics and specific supply chain, cbt manufacturing is considered costly compared to more conventional medicinal products. as a result, biomedical researchers and clinicians are increasin ... | 2020 | 32414635 |
real-world gaseous and particulate emissions from euro iv to vi medium duty diesel trucks. | this study offers emission factors for earlier and late technology medium duty diesel particulate filter (dpf) -equipped trucks, operating on real-world conditions. the analysis includes levels of nitrous oxide (n2o) emissions as well as the impacts of dpf regenerations on emission levels. the real-driving gaseous and particulate emissions, as well as fuel consumption of 14 euro iv, euro v, and euro vi medium duty diesel trucks were analysed and the efficiency of different emission control techn ... | 2020 | 32413659 |
the cost and the effectiveness of cholangiography for the diagnosis and treatment of a bile duct injury after difficult identification of the cystic duct. | this study aims to assess the cost and the effectiveness of intraoperative cholangiography (ioc) for the diagnosis and treatment of a bile duct injury (bdi) after incorrect or difficult identification of the cystic duct (dicd) during a cholecystectomy. | 2020 | 32410182 |
a comparison of minimally invasive and open transforaminal lumbar interbody fusion for grade 1 degenerative lumbar spondylolisthesis: an analysis of the prospective quality outcomes database. | it remains unclear if minimally invasive transforaminal lumbar interbody fusion (mi-tlif) is comparable to traditional, open tlif because of the limitations of the prior small-sample-size, single-center studies reporting comparative effectiveness. | 2020 | 32409828 |
do custom 3d-printed revision acetabular implants provide enough value to justify the additional costs? the health-economic comparison of a new porous 3d-printed hip implant for revision arthroplasty of paprosky type 3b acetabular defects and its closest alternative. | total hip arthroplasty (tha) is a common operation for patients suffering from hip arthrosis. it has been proven effective in improving quality of life while being cost-effective. meanwhile, the number of revision hip arthroplasty is growing and those may require bone reconstruction and are potential indications for 3d custom implants. in these specific indications, medical 3d-printing has grown over the years and the use of 3d-printed implants has become more frequent. to date, the cost-effecti ... | 2020 | 32409268 |
lineage-specific differences in lipid metabolism and its impact on clinical strains of mycobacterium tuberculosis. | mycobacterium tuberculosis (m. tb) is the causative agent of tb and its incidences has been on the rise since 1993. lipid metabolism is an imperative metabolic process, which grants m. tb the ability to utilize host-derived lipids as a secondary source of nutrition during infection. in addition to degrading host lipids, m. tb is proficient at using lipids, such as cholesterol, to facilitate its entry into macrophages. mycolic acids, constituents of the mycobacterial cell wall, offer protection a ... | 2020 | 32407863 |
financial distress and its impact on symptom expression in advanced cancer patients. | to assess financial distress (fd) and its impact on symptom expression and other quality of life issues patients and methods: advanced cancer patients admitted to inpatient and outpatient clinics were selected. standard epidemiological data including age, gender, primary cancer diagnosis, and karnofsky level were recorded. data regarding marital status, number of cohabitants, religious belief, educational level, and family income (< 1000, 1000-3.000, > 3000 euros), as well as extra costs not cov ... | 2020 | 32405963 |
stenting the ureteroneocystostomy reduces urological complications in kidney transplantation: a noninferiority randomized controlled trial, splint trial. | the role of ureteral stents in living-donor kidney transplantation remains uncertain. in this randomized controlled trial (splint), we compared urological complications in living-donor kidney transplantations performed with or without stents. we included 200 consecutive patients that received living-donor kidney transplantations at the erasmus mc, university medical center, rotterdam. patients (124 males, 76 females, mean age 54 ± 13) were randomized for suprapubic externalized single j stents ( ... | 2020 | 32403158 |
how do drivers negotiate intersections with pedestrians? the importance of pedestrian time-to-arrival and visibility. | forward collision warning (fcw) and autonomous emergency braking (aeb) systems are increasingly available and prevent or mitigate collisions by alerting the driver or autonomously braking the vehicle. threat-assessment and decision-making algorithms for fcw and aeb aim to find the best compromise for safety by intervening at the "right" time: neither too early, potentially upsetting the driver, nor too late, possibly missing opportunities to avoid the collision. today, the extent to which activa ... | 2020 | 32402866 |
authors' correction for euro surveill. 2020;25(17). | 2020 | 32400360 | |
quantifying the economic impact of caregiving for duchenne muscular dystrophy (dmd) in spain. | to establish the potential economic burden in caregivers to patients with dmd and the potential causative factors. | 2020 | 32399780 |
gardening in ashes: the possibilities and limitations of gardening to support indigenous health and well-being in the context of wildfires and colonialism. | in this paper, we will discuss gardening as a relationship with nature and an ongoing process to support indigenous health and well-being in the context of the climate crisis and increasingly widespread forest fires. we will explore the concept of gardening as both a euro-western agriculture practice and as a longstanding indigenous practice-wherein naturally occurring gardens are tended in relationship and related to a wider engagement with the natural world - and the influences of colonialism ... | 2020 | 32397077 |
climate change patterns in precipitation over spain using cordex projections for 2021-2050. | this work presents an analysis of the climate change scenarios in some extreme precipitation indices over spain using simulations from the euro-cordex project. change projections of precipitation are evaluated for the near future (2021-2050) relatively to a reference past climate (1971-2000). projections of annual precipitation show a general decrease in almost the whole region except over the central area where positive changes are detected due to a significant increase in winter. for consecuti ... | 2020 | 32392673 |
diversity and distribution of the millipedes (diplopoda) of georgia, caucasus. | the diplopod fauna of georgia, transcaucasia, is very rich given the country's relatively small territory; it presently comprises 103 species from 44 genera, 12 families, and 7 orders. most of the diplopoda known from georgia (86 species, or 83%) demonstrate caucasian distribution patterns, 36 and 46 species, as well as 8 and 9 genera being endemic or subendemic to the country, respectively. a single holarctic family, anthroleucosomatidae (order chordeumatida), contains 44 caucasian species and ... | 2020 | 32390753 |
a social cost-benefit analysis of meat taxation and a fruit and vegetables subsidy for a healthy and sustainable food consumption in the netherlands. | implementation of food taxes or subsidies may promote healthier and a more sustainable diet in a society. this study estimates the effects of a tax (15% or 30%) on meat and a subsidy (10%) on fruit and vegetables (f&v) consumption in the netherlands using a social cost-benefit analysis with a 30-year time horizon. | 2020 | 32389120 |
is testing of aspartate aminotransferase necessary along with every alanine aminotransferase for health check in elderly individuals? | this study is to evaluate whether aspartate aminotransferase (ast) is necessary to screen for liver function in apparently healthy elderly individuals. | 2020 | 32380092 |
preoperative intragastric balloon in morbid obesity is unable to decrease early postoperative morbidity of bariatric surgery (sleeve gastrectomy and gastric bypass): a clinical assay. | there are few studies that investigate the usefulness of the preoperative intragastric balloon (igb). this study will evaluate if pre-surgical weight loss with igb reduces morbidity and mortality after surgery. | 2020 | 31399943 |
cost-effectiveness analysis of peripheral nerve field stimulation as add-on therapy to spinal cord stimulation in the treatment of chronic low back pain in failed back surgery syndrome patients. | presently, there is only limited evidence about the cost-effectiveness of peripheral nerve field stimulation (pnfs) and no evidence to date on the cost-effectiveness of pnfs as an add-on therapy to spinal cord stimulation (scs). in a multicenter randomized controlled trial, pnfs as add-on therapy to scs demonstrated clinical effectiveness in treating chronic low back pain in failed back surgery syndrome (fbss) patients. we report here the cost-effectiveness of pnfs as additional therapy. | 2020 | 31423686 |
pre-emptive deceased-donor kidney transplant: a matched cohort study. | currently, kidney transplantation is the treatment of choice for patients with kidney disease who require replacement therapy. dialysis is a necessary step, but not mandatory prior to transplantation. there is the possibility of pre-emptive transplantation or transplantation in pre-dialysis, that is, without previous dialysis. the aim of the present study is to evaluate the result of our experience with a pre-emptive kidney transplant from a deceased donor. | 2020 | 31416631 |
effect modification of the association between total cigarette smoking and als risk by intensity, duration and time-since-quitting: euro-motor. | we investigated the association between cigarette smoking and risk of amyotrophic lateral sclerosis (als) in a pooled analysis of population-based case-control studies and explored the independent effects of intensity, duration and time-since-quitting. | 2020 | 31434759 |