Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| methotrexate analogs. 3. synthesis and biological properties of some side-chain altered analogs. | 1974 | 4213249 | |
| parasitic protozoa of the blood of rodents: a revision of plasmodium berghei. | 1974 | 4214369 | |
| prospects for vaccination against malaria in man. | rodents have been successfully protected against a challenge of viable plasmodium berghei by employing as vaccine: (1) the irradiated blood stages of the same parasite, or (2) the water-insoluble fraction of the blood stages, or (3) irradiated sporozoites; all these vaccines were shown to be stage-specific. a method is outlined for testing in the field, in the absence of any risks, the efficacy of analogous vaccines against falciparum malaria in man. it is emphasized that: (1) the efficacy of th ... | 1974 | 4216411 |
| recent advances in antimalarial chemotherapy and drug resistance. | 1974 | 4217563 | |
| the chemotherapy of rodent malaria. xx. autophagic vacuole formation in plasmodium berghei in vitro. | 1974 | 4374902 | |
| the effect of rowson-parr virus on the severity of malaria in mice. | 1974 | 4375171 | |
| inhibition of the immune response to pertussis vaccine during plasmodium berghei yoelii infection in mice. | mice infected with plasmodium berghei yoelii responded poorly to pertussis vaccine when administered at peak parasitemia. this was shown by serum agglutinin titers and lack of protection against intracerebral challenge with virulent bordetella pertussis. | 1974 | 4375413 |
| synthesis of potential antimalarial agents. preparation of some 6-amino-5,8-dimethoxyquinolines and the corresponding 6-amino-5,8-quinolinediones. | 1974 | 4598023 | |
| naphthothiophenes. 4. preparation of multisubstituted 4-naphtho(2,1-b)thiophenemathanols and the effect of side chain modification on antimalarial activity of 8-trifluoromethyl-4-naphtho(2,1-b)thiophenemethanols. | 1974 | 4598132 | |
| antimalarials. 6. synthesis, antimalarial activity, and configurations of racemic alpha-(2-piperidyl)-4-pyridinemethanols. | 1974 | 4598133 | |
| synthesis and antimalarial activity of anthracene amino alcohols. | 1974 | 4598134 | |
| antimalarials. 2. alpha-di-n-butylaminomethyl-2-(p-chlorophenyl)-5-quinazolinemethanol. | 1974 | 4598262 | |
| effective recovery and immunity to virulent malaria following red cell transfusion at crisis. | 1974 | 4599485 | |
| potential antimalarials. 8. some 10-substituted 9-phenanthrenemethanols. | 1974 | 4599520 | |
| antimalarial, antiamoebic and toxicity tests on gentianine. | 1974 | 4599567 | |
| high-affinity accumulation of chloroquine by mouse erythrocytes infected with plasmodium berghei. | washed erythrocytes infected with chloroquine-susceptible (cs) or with chloroquine-resistant (cr) p. berghei were used in model systems in vitro to study the accumulation of chloroquine with high affinity. the cs model could achieve distribution ratios (chloroquine in cells: chloroquine in medium) of 100 in the absence of substrate. 200-300 in the presence of 10 mm pyruvate or lactate, and over 600 in the presence of 1 mm glucose or glycerol. in comparable studies of the cr model, the distributi ... | 1974 | 4600044 |
| the mitochondria of pre-erythrocytic plasmodium berghei. | 1974 | 4600125 | |
| ultrastructural analysis of plasmodium berghei sporozoite antigens prepared by freeze thawing and heat inactivation. | 1974 | 4600225 | |
| synthesis of analogs of 6-arylthio-, 6-arylsulfinyl-, and 6-arylsulfonyl-2, 4-diaminoquinazolines as potential antimalarial agents. | 1974 | 4600305 | |
| the chemotherapy of rodent malaria, xix. the action of a tetracycline derivative, minocycline, on drug-resistant plasmodium berghei. | 1974 | 4602012 | |
| fluorescent-antibody cross reactions between four blood parasites. | 1974 | 4602679 | |
| dihydropteroate synthetase from plasmodium berghei: isolation, properties, and inhibition by dapsone and sulfadiazine. | 1974 | 4602912 | |
| the surface of the malaria parasite. i. scanning electron microscopy of the oocyst. | 1974 | 4602986 | |
| synthesis and screening of potential antimalarial agent alpha-(2-piperidyl)-2-(1-adamantyl)-6,8-dichloro-4-quinolinemethanol hydrochloride. | 1974 | 4605197 | |
| a structural modification study of the antimalarial 2-(p-chlorophenyl)-2-(4-piperidyl)tetrahydrofuran. | 1974 | 4606154 | |
| amodiaquine analogs. synthesis of 6-((3-(n,n-diethylamino)methyl-4-hydroxy)anilino)5,8-dimethoxy-2,4-dimethylquinoline and related compounds. | 1974 | 4606204 | |
| antimalarials. 4. tetrahydroquinolinemethanols. | 1974 | 4606233 | |
| chemotherapy of rodent malaria: transfer of resistance vs mutation. | 1974 | 4606333 | |
| plasmodium berghei berghei: ectopic development of the anka strain in anopheles stephensi. | 1974 | 4606913 | |
| plasmodium berghei: possible role of thyroxine in growth and metabolism. | 1974 | 4606914 | |
| quinazolines. 12. 1,3-diaminobenzo(f)quinazolines containing long-chain alkyl or chloro substituents on the central ring. synthesis and biological evaluation as candidate antifolate and antimalarial agents. | 1974 | 4606974 | |
| scanning electron microscope observations of plasmodium berghei ookinetes in primary mosquito cell cultures. | 1974 | 4607047 | |
| slow maturing primary exo-erythrocytic schizonts of plasmodium berghei in an experimentally infected tree-rat (thamnomys surdaster). | 1974 | 4607414 | |
| variation in glutamate dehydrogenase in subspecies of plasmodium berghei. | 1974 | 4607629 | |
| selections of anopheles gambiae species a for susceptibility and refractoriness to malaria parasites. | 1974 | 4607768 | |
| proceedings: the effect of mouse haemoglobins of plasmodium berghei and babesia rodhaini infections. | 1974 | 4607933 | |
| proceedings: the interaction between an ascites tumour and rodent malarias in mice. | 1974 | 4607934 | |
| letter: relation between plasmodium berghei and hepatosplenic and blood rates of paba and folates in mice. | 1974 | 4608060 | |
| synthesis and antimalarial evaluation of 9,10-dihydrophenanthrene amino alcohols. | 1974 | 4608227 | |
| an experimental approach to the demonstration of a single generation of exo-erythrocytic schizonts in plasmodium berghei. | 1974 | 4609378 | |
| erythropoietin production in virulent malaria. | erythropoietin, the hormone responsible for stimulating erythrocyte production, was shown to increase significantly in the serum of mice during virulent malaria infection. although erythropoiesis was enhanced, it did not keep pace with the rate of erythocyte destruction; hence all plasmodium berghei-infected mice quickly succumbed to the deleterious consequences of severe uncompensated hemolytic anemia. since this apparently inadequate rate of erythropoiesis is not attributed to impaired erythro ... | 1974 | 4609912 |
| in vitro ookinete development of the rodent malarial parasite, plasmodium berghei. | 1974 | 4610107 | |
| babesia microti and plasmodium berghei yoelii infections in nude mice. | 1974 | 4610411 | |
| host-cell specific proteolytic enzymes in plasmodium berghei infected erythrocytes. | 1974 | 4610782 | |
| influence of allopurinol on the multiplication of rodent malaria parasites. | 1974 | 4610931 | |
| comparison of the effects of neonatal thymectomy on plasmodium berghei, trypanosoma lewisi and trypanosoma cruzi infection in the albino rat. | 1974 | 4611081 | |
| immunity to plasmodium berghei in rats: passive serum transfer and role of the spleen. | pools of rat antiserum to plasmodium berghei had different levels of protective activity as assessed by a passive transfer test. preincubation of parasite inocula with an effective pool before injection did not significantly enhance protective activity. removal of the antiserum from preincubated parasite inocula abolished the bulk of protective activity. similarly, antiserum effective in intact animals was largely ineffective in splenectomized recipients. these experiments suggest a minimal role ... | 1974 | 4611920 |
| plasmodium berghei ookinete formation in a nonvector cell line. | 1974 | 4612127 | |
| malaria and the permeability of the host erythrocyte. | 1974 | 4612377 | |
| [treatment of drug-resistant malaria: animal experiments]. | 1974 | 4613506 | |
| ultrastructural studies on the early ookinete stage of plasmodium berghei nigeriensis and its transformation into an oocyst. | 1974 | 4614723 | |
| acid hydrolases of the sporogonic stage of plasmodium berghei nigeriensis. | 1974 | 4614726 | |
| the effect of plasmodium berghei and trypanosoma brucei infections on the immune expulsion of the nematode trichuris muris from mice. | 1974 | 4615070 | |
| the uptake and incorporation of nucleosides into normal erythrocytes and erythrocytes containing plasmodium berghei. | 1974 | 4615289 | |
| suppression of schistosome granuloma formation by malaria in mice. | plasmodium berghei yeolii infection in mice suppressed granuloma formation around schistosoma mansoni eggs in the lungs. this suppressive effect was observed as early as 4 days after schistosome eggs were injected into malaria-infected mice and the maximum suppressive effect was seen by the 16th day. at this time granulomas in control mice than in mice infected with malaria. these data suggest that malaria has a direct influence on an immunologic reaction of the delayed hypersensitivity type. th ... | 1974 | 4615597 |
| the selection of arylamidinourea antimalarials by their predicted physicochemical properties. | 1 a small group of arylamidinoureas for which the predicted physicochemical properties were widely spaced and uncorrelated was selected for study.2 the antimalarial activity of each compound was measured against three species of plasmodium. three corresponding regression equations were calculated relating the potency of each compound to its predicted physicochemical properties.3 the potency of further test compounds was forecast for each species, by using the corresponding regression equation. t ... | 1974 | 4615765 |
| erythrocyte atp levels in mice infected with plasmodium berghei malaria. | 1974 | 4617309 | |
| effect of hypothyroidism on parasitemia and survival in rodent malaria. | 1974 | 4617503 | |
| development and decline of antiplasmodial indirect fluorescent antibodies in mice infected with plasmodium berghei (nk65) and treated with drugs. | malaria parasites in mice present a simplified rodent model for the immunological study of malaria. experiments have been performed to determine the pattern and persistence of malaria antibody as detected by the indirect fluorescent antibody (ifa) test utilizing specific antimouse igm and igg conjugates. the antibody levels in mice inoculated with plasmodium berghei and treated with antimalarial drugs were traced after complete elimination of the parasites from the host. within 1-2 weeks after i ... | 1974 | 4617640 |
| [immunological aspects of plasmodium berghei infections (action of cortisone in therapeutic doses)]. | 1974 | 4618434 | |
| [evaluation of anti-plasmodium antibodies in idiopathic african splenomegaly]. | 1974 | 4618790 | |
| modification by a latent contaminant of glomerular pathology in mice infected with plasmodium berghei. | this study was designed to determine, by means of electron microscopy, the effect of latent contaminants-which are associated with the syringe passage of the parasite-on the findings in the glomeruli of p. berghei-infected mice. a rapid alteration of the glomerular basement membrane was observed in mice infected with the syringe-transmitted n strain, but not in those infected with the cyclically passaged nig strain. glomerular changes were also seen in mice inoculated with nonparasitized blood f ... | 1974 | 4619058 |
| prevention of drug resistance in rodent malaria by the use of drug mixtures. | development of resistance to chloroquine in rodent malaria is inhibited by giving this compound together with a potentiating mixture of pyrimethamine and sulfadoxine but this does not prevent the development of resistance to the last two compounds. the use of drug mixtures should be explored as a means of "protecting" chloroquine or new blood schizontocides intended for mass chemotherapy against human malaria. however, no general rule can be laid down without testing specific drug mixtures in lo ... | 1974 | 4619060 |
| [research on congenital plasmodium berghei berghei malaria in mice. transplacental passage of the parasite and its evolution]. | 1974 | 4619061 | |
| [characterization of the antigen produced by solubilization of cell membranes of plasmodium berghei]. | 1974 | 4620172 | |
| optical isomers of aryl-2-piperidylmethanol antimalarial agents. preparation, optical purity, and absolute stereochemistry. | 1974 | 4588275 | |
| 4(1h)-quinolones. 2. antimalarial effect of some 2-methyl-3-(1'-alkenyl)-or-3-alkyl-4(1h)-quinolones. | 1974 | 4588278 | |
| synthesis of 2,4-diamino-5-(4-arylthiophenyl)-and 5-(4-arylsulfonylphenyl)pyrimidines as antimalarials. | 1974 | 4590245 | |
| sulfide, disulfide, and sulfone derivatives of 2-phenylcinchoninic acid as antimalarial congeners. | 1974 | 4590249 | |
| a comparative account of the effects of betamethasone on mice infected with plasmodium vinckei chabaudi and plasmodium berghei yoelii. | 1974 | 4592839 | |
| proceedings: ultrastructural changes following treatment of plasmodium berghei with quinine, and with a 9-phenanthrenemethanol, wr 122, 455. | 1974 | 4594465 | |
| proceedings: ultrastructural studies of the oökinete of p. b. nigeriensis. | 1974 | 4594466 | |
| labeling of sporozoites of plasmodium berghei with tritiated purines. | 1974 | 4595208 | |
| plasmodium berghei: experimental rodent model for malarial renal immunopathology. | 1974 | 4595293 | |
| brain capillary blockage produced by a virulent strain of rodent malaria. | a sudden enhancement in virulence of a mild plasmodium berghei yoelii 17 x strain resulted in fulminating and fatal infections in cf1 and a/j mice. the virulent strain has maintained its characteristics after ten cyclical transmissions through anopheles stephensi. the visible expression of virulence of the mutated strain is its ability to cross the blood-brain barrier and cause intravascular sequestration of injected erythrocytes and blockage of brain capillaries. we, therfore, believe that the ... | 1974 | 4595458 |
| antimalarial quinones for prophylaxis based on a rationale of inhibition of electron transfer in plasmodium. | knowledge of the biochemistry of plasmodium is emerging as a new field. previous studies showed that the parasite apparently requires electron transfer for energy, and techniques to study such energy mechanisms are available. the discovery of the existence of coenzyme q(8) in plasmodium implies an indispensable functionality for this redox entity in the electron transfer of the parasite, as coenzyme q(n) similarily functions in other forms of life. effective antimalarial activity in prophylaxis ... | 1974 | 4595578 |
| cross immunofluorescent reactions between human and rodent malaria. | 1974 | 4594072 | |
| [preparation of an anti-plasmodium berghei serum using the mouse and the rabbit]. | 1973 | 4594318 | |
| the challenge of drug-resistant malaria. | 1973 | 4631761 | |
| infectivity of plasmodium berghei and of babesia rodhaini to various primates. | 1973 | 4631764 | |
| a direct counting technique for estimating high parasitaemias in infections of babesia argentina, babesia bigemina and plasmodium berghei. | 1973 | 4595621 | |
| chemotherapeutic activity of combination doses of chloroquine, pyrimethamine, and sulfamethoxy-diazine, a long-acting sulfanilamide, against plasmodium berghei infections in mice. | during the course of antimalarial screening, it was discovered that sulfamethoxydiazine, a long-acting sulfanilamide extensively used in genitourinary tract infections, not only was effective against plasmodium berghei infections in mice when administered alone but also was active when used in combination with chloroquine, in effect making it possible to use half as much of the latter drug as normally required to achieve the same results. the triple combination of chloroquine, sulfamethoxydiazin ... | 1973 | 4597722 |
| enzyme variation in plasmodium berghei and plasmodium vinckei. | 1973 | 4595114 | |
| genetic recombination in plasmodium berghei. | 1973 | 4595115 | |
| some factors influencing the induction, maintenance and degree of maternally transmitted protective immunity to malaria (plasmodium berghei). | 1973 | 4593640 | |
| influence of various cooling and warming temperatures on survival after thawing of cryopreserved plasmodium berghei. | 1973 | 4574975 | |
| autoimmunity in plasmodium berghei malaria. | 1973 | 4590388 | |
| two lines of p. berghei berghei resistant to a phenanthrene methanol. | 1973 | 4591213 | |
| the action of minocycline, a tetracycline derivative on drug-resistant p. berghei. | 1973 | 4591214 | |
| 1. isocitrate dehydrogenase activity in relation to the mitochondrial changes during the life-cycle of p. berghei. 2. observations on the host-parasite relationship between p. berghei and the mouse reticulocyte. | 1973 | 4591215 | |
| uptake of 3h-adenosine and 3h-thymidine by oöcysts of p. berghei berghei. | 1973 | 4591216 | |
| 1. carbohydrate metabolism in p. berghei: preliminary observation. 2. chloroquine-induced pigment clumping in p. berghei: dependence on composition of the medium. | 1973 | 4591217 | |
| plasmodium berghei: detection in organs of infected mice by means of immunofluorescence. | 1973 | 4591505 | |
| a comparative study on the ultrastructure of plasmodium sporozoites within the oöcyst and salivary glands, with particular reference to the incidence of the micropore. | 1973 | 4591782 | |
| [selective invasion of reticulocytes by parasites of plasmodium berghei berghei strain with acquired resistance to chloroquine]. | 1973 | 4588788 | |
| suppression of plasmodium berghei parasitaemia and enhancement in survival by reticuloendothelial stimulation. | 1973 | 4588949 | |
| summary of recent abstracts. 3. malaria. 1. | 1973 | 4573170 | |
| the effect of malaria on the relative affinity of mouse antiprotein antibody. | 1973 | 4573426 | |
| depression of immune response to moloney leukaemia virus by malarial infection. | 1973 | 4573475 | |
| the immunological significance of histological changes in the spleen and liver in mouse malaria. | 1973 | 4573765 |