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contrasting effects of nifedipine and adenosine on regional myocardial flow distribution and metabolism distal to a severe coronary arterial stenosis: observations in sedated, closed-chest, domestic swine.this study tested the hypothesis that intrinsic negative inotropic effects of a drug used to induce coronary vasodilation distal to a severe coronary arterial stenosis may influence the extent of redistribution of transmural flow and its metabolic consequences. to test this hypothesis, studies were conducted in eight closed-chest, sedated swine with severe (82% reduction in luminal diameter) coronary arterial stenoses. measurement of hemodynamic parameters, regional myocardial blood flow (micros ...19846705159
nor activity, heterochromatin differentiation, and the robertsonian polymorphism in sus scrofa l.the karyotype of the european wild pig (sus scrofa scrofa l.) was analysed by means of silver-staining and the chromomycin a3/distamycin a/dapi fluorescent banding technique to locate active nors and to differentiate types of c-bands. the ribosomal rna genes are localized at the secondary constrictions of chromosomes 8 and 10. all biarmed chromosomes, with the exception of chromosome 15/17 and the y, had a chromomycin bright centromeric region that was moderately fluorescent with distamycin a/da ...19846707448
influence of adenosine on basal myocardial function: observations in anaesthetised, domestic swine.data from experiments in isolated cardiac muscle preparations indicate that adenosine in high concentration (10(-3) mol x litre-1) exerts a negative inotropic effect on the myocardium under basal conditions. the following study was performed to test the hypothesis that adenosine exerts a similar negative inotropic effect when administered in an intact animal model in a dose sufficient to cause maximal coronary vasodilatation. six open chest anaesthetised pigs were studied as follows. ultrasonic ...19846713450
[pre- and perinatal oxygen transport in mammals: the embryonic hemoglobins of the domestic pig (sus scrofa domestica)].pigs express two globin genes of beta-type, the epsilon- and chains during their embryonic stage. with the alpha- and epsilon-chains they form four embryonic hemoglobins. we describe here in detail the experimental procedures for sequencing the epsilon- and chains from the pig (sus scrofa domestica) and we discuss the data with respect to their special functional properties. from the components gower i and heide i, we obtained all embryonic chains by chromatography on cm-cellulose. the sequence ...19846724525
reciprocal chromosome translocation with transfer of centromeric heterochromatin in the domestic pig karyotype. 19846725001
effects of low energy laser on wound healing in a porcine model.low energy helium neon laser has been suggested as an effective adjuvant in the healing of open wounds. to date, supportive studies have been performed in loose-skinned animals. for such data to be clinically meaningful, it was felt necessary to study this effect in an animal with a dermal structure more closely resembling that of man, the pig. after creating 62 partial thickness wounds on the dorsum of domestic swine, one-half of these were randomized to receive laser treatment. the remainder s ...19846727528
trichinella isolates from polar bears in svalbard. freeze resistance and infectivity in rats and swine.the author isolated trichinella strains from five polar bears in svalbard (the high arctic region of norway). based on infectivity experiments with white mice (bom:nmr), the freeze resistance limits of the trichinella strains are outlined. further experiments showed that white rats (mol:wist) and pigs (sus scrofa domestica) are almost refractory to these trichinella strains. the infectivity of svalbard isolates in the above mentioned test animals was compared, in parallel experiments, with that ...19846728674
experimental infection of domestic swine with baylisascaris procyonis from raccoons.six 8-week-old ascarid-naive pigs which were experimentally infected with 72,000 embryonated baylisascaris procyonis eggs of raccoon origin developed lesions limited to the intestines and liver. intestinal lesions consisted of multifocal areas of inflammation by macrophages, eosinophils, and lymphocytes in the mucosa and submucosa, in association with baylisascaris larvae; similar lesions were seen in the mesenteric lymph nodes. typical white, granulation type, multifocal interstitial hepatitis ...19846742572
allergic contact dermatitis in the domestic pig. a new model for evaluating the topical anti-inflammatory activity of drugs and their formulations. 19846743545
immunohistochemical demonstration of target cells for sexual hormones in the skin of the domestic pig. 19846380731
fetal pancreas transplantation in miniature swine. i. developmental characteristics of fetal pig pancreases.the genetically defined miniature pig developed by sachs et al. was selected as a large animal model to test the feasibility of fetal pancreas transplants for reversal of insulin-dependent diabetes. in order to test our approach, the first key was to characterize the development of the pig pancreas tissues throughout fetal life. pancreas samples were obtained from 102 farm pig fetuses ranging in age from 35-110 days and from 39 minipig fetuses removed by caesarean section from 5 timed-pregnant s ...19846388058
blood acid-base curve nomogram for immature domestic pigs.the purpose in this study was to characterize the acid-base status of arterial blood from healthy young domestic swine and to construct an acid-base curve nomogram appropriate to such animals. accordingly, 40 immature, 20- to 31-kg domestic pigs were used to establish acid-base characteristics for arterial blood. samples were collected from chronically implanted catheters while the animals were maintained under steady-state, near-basal conditions. at a measurement temperature of 38 c, ph average ...19836419652
benzoyl peroxide and epidermal wound healing.the effectiveness of 10%, 20%, and 50% benzoyl peroxide in a lotion, 20% benzoyl peroxide in a gel, and the effect of the vehicles alone on wound reepithelialization were evaluated in young domestic pigs. twenty percent benzoyl peroxide suspension in a lotion base substantially increased the rate of reepithelialization by 33% over a seven-day evaluation period. twenty percent benzoyl peroxide suspension in a gel base and 10% benzoyl peroxide suspension in a lotion base slightly enhanced epiderma ...19836824360
effect of mechanical load in wound healing.this study was designed to investigate the effect of sequentially increasing mechanical load on healing incisions. full-thickness incisions were made on the back of a young domestic pig. during the period of fibroplasia, one of the incisions was mechanically loaded with a subcutaneous tissue expander. mechanical and histological evaluations of mechanically loaded and control incision areas indicated that the mechanical stress encouraged healing and remodeling of dermal tissue.19836838129
[comparative histometrical and histological studies of skeletal muscles in wild and domestic swine]. 19836847599
role of adenosine in the maintenance of coronary vasodilation distal to a severe coronary artery stenosis. observations in conscious domestic swine.the purpose of this study was to test the hypothesis that adenosine is required to maintain arteriolar vasodilation distal to a severe coronary stenosis. eight closed-chest conscious pigs were prepared by placing a 7.5-mm long stenosis (82% lumenal diameter reduction) in the proximal left anterior descending coronary artery. regional myocardial blood flow (microsphere technique) was measured at control 1, after 10 minutes of intracoronary infusion of adenosine deaminase (7-10 u/kg per min) dista ...19836861296
assignment of superoxide dismutase (sod-1) gene to chromosome no. 9 of domestic pig.pig--mouse somatic cell hybrids were obtained by fusing pig lymphocytes with mouse cells of the rag (hptr-) line using polyethylene glycol. the expression of pig superoxide dismutase (sod-1) activity in 11 hybrid clones as well as in the parental cells was investigated. seven hybrid clones positive for the expression of pig sod-1 displayed the corresponding parental rag and pig bands of sod-1 plus a heteropolymeric band of intermediate electrophoretic mobility. the positive and negative expressi ...19836883177
the effect of occlusive dressings on collagen synthesis and re-epithelialization in superficial wounds.the effects on superficial wounds in domestic pigs of (1) two different occlusive dressings, (2) non-occlusive wet to dry gauze dressings, and (3) air exposure were compared. collagen synthesis and re-epithelialization were increased in the wounds treated with occlusive dressings. re-epithelialization was increased beneath both the oxygen-impermeable and the oxygen-permeable dressing. when they were removed the wet to dry gauze dressing and one of the occlusive dressings often damaged the new ep ...19836887836
effect of chronic guanethidine treatment on vascular norepinephrine content in the neonatal domestic pig.vinblastine, 6-hydroxydopamine, and antibody to nerve growth factor have been shown to destroy sympathetic neurons in neonatal rats. high doses of guanethidine produce permanent sympathectomies in the adult or newborn rat. similar studies in the cat, rabbit, and hamster demonstrate that the sympathetic nervous systems are not destroyed with guanethidine. to produce permanent sympathectomy in a large animal model, guanethidine was administered to neonatal pigs. as with the cat, rabbit, and hamste ...19836888189
estimation of instantaneous blood flow through a rigid, coronary artery stenosis in anaesthetised domestic swine. 19836616522
[development of fiber type composition and fiber diameter in the longissimus muscle of the domestic pig (sus scrofa domesticus)].the development of fiber types composition and fiber diameter in porcine longissimus muscle from birth to the age of 5 years was examined by means of cross-sectional study. the fiber types were classified in the following manner: ftg = fast-twitch-glycolytic, fto = fast-twitch-oxidative and sto = slow-twitch-oxidative. the percentage on the oxidative fibers decrease from 60.8% on the 1st d to 39.1% on the 100th d of life. on the 1800th d only 26.5% oxidative fibers are present. the average diame ...19836625187
fine structure of the retinal rods and cones in the domestic pig.the structure of the retinal photoreceptors of the domestic pig has been studied by both light and electron microscopy. in this species the photoreceptors can be traditionally and adequately differentiated into rods and cones, with rods being the more numerous. rods are long, slender cells, while cones are shorter and stouter. both rods and cones consist of an outer segment, a connecting cilium, an inner segment, a nuclear region and a synaptic process leading to a synaptic ending. differences a ...19836629020
histochemistry of complex carbohydrates in the hairy skin of the domestic pig.the hairy skin from eleven body areas of the domestic pig has been studied by means of a series of selected methods for the detection of complex carbohydrates, including peroxidase-labelled lectin-diaminobenzidine procedures. the results obtained were most distinctive in the areas where the skin accessories were involved. the complex carbohydrates in the epidermis appear to be acidic and neutral glycoproteins containing a small amount of sialic acid residues. the dermal connective tissue fibres ...19836629851
[morphologic and functional myocardial changes in experimental pulmonary artery embolism].after acute experimental obstruction of the pulmonary artery, focal ultrastructural lesions of the right ventricular myocardium were observed in domestic swine. these lesions, mainly myofibrillar fragmentation, were not reflected in hemodynamic measurements, which remained unchanged.19836636794
[clinical and animal experiment studies on the pathogenetic significance of small intestine diseases and resections for urolithiasis].the authors report on metabolic studies on growing domestic pigs with resected ilea on a diet supplemented with oxalic acid and calcium. the content of calcium, magnesium and phosphate in the kidneys and ribs was determined and their excretion in urine was measured. the supplement of oxalic acid in the diet mainly affects the calcium content of the kidneys. it is also likely that oxalic acid inhibits the accumulation of calcium in the skeleton. hyperoxaluria and hyperphosphaturia were establishe ...19836637170
the possibility of detecting fetal lymphocytes in the maternal blood of the domestic pig, sus scrofa.fourteen pregnant sows were examined to determine if transplacental migration of fetal lymphocytes had occurred. giemsa-stained and c-banded karyotypes were examined. male metaphases constituted 1% to 4% of all metaphases of peripheral blood leukocytes of pregnant sows. regardless of the experimental method or stage of gestation, no essential differences were found in the number of male cells.19836641289
[mathematic approximations of mass growth in pig fetuses and comparison with homo sapiens].values for fetal mass growth over unequal time intervals of pregnancy as given by brune (1972) for the domestic pig are submitted to nonlinear regressions in order to achieve mathematical approximations. altogether 7 functions of organic growth are considered in their unbound form, as fetal mass growth is extremely slow in the 1st quarter of gravidity thus outruling the necessity of introducing an exact initial value. in contrast to many other investigations into organic growth all functions yie ...19836653997
partial ablation of the kidney by intraarterial ethanol in domestic swine.partial renal ablation was produced in 15/17 swine kidneys after segmental intraarterial injection of 1-2 ml of 95% ethanol. complications were seen in 3 kidneys, including reflux of ethanol into nontarget vessels with subsequent total infarction of 2 kidneys, and the development of hydronephrosis in 1 kidney. strictly selective catheterization and a very slow injection of ethanol are essential to avoid complications. this technique may find clinical application and the possible indications are ...19836659203
occurrence of two different reciprocal translocations in the same litter of domestic pigs. 19836668212
genome size of man and animals relative to the plant allium cepa.a direct feulgen-cytophotometric comparison of the genomic dna content (c value) was performed between the liliaceous plant species allium cepa and a number of animal species to reassess the genome size ratios between plants and animals. these appeared unduly ambiguous as a consequence of divergent picogram estimates in several animal reference species. taking 1c = 16.75 pg for allium cepa, the estimates were (1c value in picograms): man, 3.11; indian muntjak ccl 157 cell line, 2.68; domestic pi ...19836671147
blood coagulation studies in domestic pigs (hanover breed) and minipigs (goettingen breed).blood coagulation studies were performed on 60 hanover domestic pigs ready for slaughter and a total of 84 goettingen minipigs. a tendency to hypercoagulability was found in these pigs, expressed in a shortened ptt, r- and k-time in the thromboelastogram and a slightly reduced plasminogen and plasmin level. many values were similar to those of man. thrombin time was longer. this may be due more to enhanced formation of fibrin degradation products (anti-thrombin vi) than to greater amounts of end ...19836678359
[mapping of the locus for the h blood-group system on the 15th chromosome of domestic swine]. 19836593198
cell cycle time and possible early dna replication in c-band regions in the domestic pig (sus scrofa) lymphocytes.dynamic cell replication studies on peripheric blood lymphocytes cultured from the domestic pig (sus scrofa) were performed. replication started after 18-24 hr in culture and the cell cycle time was about 8-10 hr. chromosomes from cells at first division showed c-banded-like regions. this finding suggests the occurrence of early dna replication zones within the constitutive heterochromatin of the pig chromosomes.19836607699
density profile and cholesterol concentration of serum lipoproteins in pigs (sus scrofa domestica) fed a hypercholesterolemic diet. preliminary results. 19836583920
domestic pigs in the study of myocardial ischemia.during the last 10 years there has been a growing interest in the use of domestic pigs in the study of various aspects of myocardial ischemia. while most studies are still performed on dogs, a number of scientific and non-scientific (emotional) reasons have led to a shift from the use of the former to that of domestic pigs. in this paper the suitability of the pig for cardiovascular studies is dealt with, with special attention to the coronary and collateral circulation. a number of manifestatio ...19836352271
motoneurons of m. semitendinosus in domestic and wild pigs. a horseradish peroxidase and cord-survey study.in domestic and wild pigs motor nuclei of the m. semitendinosus were labelled by retrograde transport of horseradish peroxidase (hrp) from muscle to spinal cord. further motoneurons in the lumbosacral cord were stained with luxol-fast-blue and cresyl violet. motoneurons innervating m. semitendinosus were present in the ventral horns of the last (6th) lumbal and the first sacral cord segments. they were localized within two motor columns lying parallel to each other in the medial and lateroventra ...19836193741
[embryonic hemoglobins in mammals: sequences of zeta-, epsilon- and theta chains in domestic pigs (sus scrofa domestica)].the amino-acid sequences of all expressed hemoglobins of the pig embryo are given: hemoglobin gower i (zeta 2/epsilon 2), hemoglobin gower ii (alpha 2/epsilon 2), hemoglobin heide i (zeta 2/theta 2) and hemoglobin heide ii (alpha 2/theta 2). the zeta-, epsilon- and theta-chains were obtained with chromatography on cm-cellulose from isolated hemoglobin components. the primary structure was established by sequencing the tryptic peptides in the sequenator: they were isolated using hplc. the zeta-ch ...19836195840
gonadotrophic stimulation of androgen secretion by the early fetal pig ovary in organ culture.an influence of gonadotropins on steroid secretion by the early fetal ovary of the domestic pig was shown by organ culture and radioimmunoassay. gonads from fetuses at days 32-37 of gestation were cultivated singly for 9-12 days in biologically supplemented medium. one member of each pair of gonads was exposed to human chorionic gonadotropin (hcg) or ovine luteinizing hormone (lh), and the other served as a control. a marked stimulating effect on androgen secretion was noted with both gonadotrop ...19836299410
coronary constriction by leukotriene c4, d4, and e4 in the intact pig heart.leukotrienes are naturally occurring vasoactive metabolites of arachidonic acid that increase during inflammatory reactions and anaphylaxis. coronary constriction and reduced myocardial contractility after leukotriene c4 and d4 administration were demonstrated in the isolated guinea pig heart. to explore the effects of leukotrienes in the in situ, blood-perfused heart, we administered leukotrienes c4, d4, and e4 into the coronary artery of the domestic pig. increasing doses (0.1, 0.3, 1.0, and 3 ...19836303103
the healing of superficial skin wounds is stimulated by external electrical current.we studied the effects of direct electric current supplied by an energized silver-coated electrode on dermal and epidermal wound healing. keratome-induced wounds (0.3 mm deep) on the skin of young domestic pigs were treated with either an energized (50-300 microa) electrode (dc), an unenergized electrode (placebo), or left untreated. wounds were excised on days 1-7 after wounding and the epidermis was separated from the dermis. the epidermal sheet was evaluated for reepithelialization and the de ...19836308102
the localization of genes for hprt, g6pd, and alpha-gal onto the x-chromosome of domestic pig (sus scrofa domesticus).pig--mouse somatic cell hybrids were obtained from fusion of hprt--mouse cells (rag) and pig lymphocytes. the pig-mouse hybrids examined apparently retained on the average only 9 to 15 pig chromosomes. seven of the hybrid clones were karyotyped to determine the pig chromosome constitution, and the same hybrid clones were tested electrophoretically for the expression of pig hypoxanthine-guanine phosphoribosyltransferase (hprt), glucose-6-phosphate dehydrogenase (g6pd), and alpha-galactosidase (al ...19836309343
the formation of unconjugated and sulfoconjugated estrogens by leydig cells of the boar testis.the metabolism of radioactive androstenedione (a) and estrone (e1) was examined in preparations of enzyme-dispersed cells from testicular interstitial tissue of the boar. incubations were made with two-cell populations from a discontinuous density gradient (10-90% percoll). products were separated into unconjugated and "conjugated" (water-soluble) fractions by countercurrent distribution (ccd) using an ether-water partition. as much as 75% of a and 20-25% of e1 appeared in the aqueous phase. unc ...19836313165
influenza virus a/swine-outbreaks in domestic pigs and antibody findings in human sera.in the last years, the occurrence of influenza viruses a/h1n1 (hsw1n1) in pig stocks of different countries has been increasingly reported. in general, the isolated viruses were related to the influenza virus a/new jersey/8/76 h1n1 (hsw1n1). human infections were not reported in these outbreaks. since march 1981, very limited influenza outbreaks in several pig stocks of the gdr with high morbidity and very low lethality have been observed. the illness took an uncomplicated path and generally sub ...19836316691
metabolism of c19 steroids in vitro by the submaxillary salivary gland of mature and immature domestic pigs.homogenates of the submaxillary glands of immature and mature pigs were incubated with 3h-labelled c19 steroids which have been shown previously to be metabolized in vitro by the submaxillary gland of mature boars. dehydroepiandrosterone was metabolized largely to androstenedione, 5 alpha-androstane-3,17-dione and androsterone, and to small amounts of testosterone, 5 alpha-dihydrotestosterone and 5 alpha-androstanediols. testosterone yielded predominantly 5 alpha-androstane-3 alpha, 17 beta-diol ...19826461710
the interposition of lyodura in operations for ankylosis of the temporo-mandibular joint. an experimental study using pigs.experimental investigations using domestic pigs were carried out in order to study the subject of resorption of lyophilized dura (lyodura) interposed in the region of the temporo-mandibular joint after operations for ankylosis. the condyle of the mandible was partially resected on one or both sides, the joint capsule and disc excised and the mandibular fossa stripped of cartilage. lyodura was interposed between the surfaces of the bones and intravital sequential labelling of the bones was carrie ...19826961178
fluoride pharmacokinetics in the domestic pig.plasma fluoride concentrations were studied in 11 pigs following single oral or intravenous doses of fluoride. the results showed a less-than-20% bioavailability of fluoride when administered with calcium-rich food. pharmacokinetic analyses showed that the plasma half-life varied from 0.6 to 1.4 h, depending on diet and route of fluoride administration. these data are comparable to those reported for man, and thus illustrate the suitability of the pig for studies of effects of fluoride on hard t ...19826963284
a robertsonian translocation in the domestic pig (sus scrofa) 37,xx,-13,-17,t rob(13;17). 19826979301
intraperitoneal insulin administration produces a positive portal-systemic blood insulin gradient in unanesthetized, unrestrained swine.the present study was performed to evaluate the porto-systemic insulin gradient in response to (1) glucose feeding (2) intramuscular insulin administration, and (3) peritoneal insulin administration in unanesthetized swine. the experiment was designed to verify the hypothesis that intraperitoneal insulin administered might lead to a more physiologic portal vein insulin concentration than systemic administration of a similar insulin dose. studies were performed in 4 domestic swine with chronic, i ...19826752635
immunocytological study of the chronology of pituitary cytogenesis in the domestic pig (sus scrofa) with special reference to the functioning of the hypothalamo-pituitary-gonadal axis.this paper reports an immunofluorescent study of the pituitary in the fetal pig (sus scrofa). fifteen antisera were used against most of the hormones present in the pituitary. five types of hypophysial endocrine cells were observed in the anterior and intermediate lobes. we determined the sequential appearance of these various cell types in the fetus. the first hormones found at 33 days were acth, beta-msh, beta- and gamma-lph and alpha- and beta-endorphin; alpha-msh appeared at 40 days and sth ...19826760297
[alloxan induced long term diabetes in the domestic pig. i].an insulin-deficient diabetes of long duration was induced by intravenous injection of alloxanmonohydrate (200 mg/kg and 100 mg/kg body mass, respectively) in 23 pigs (landrace, duroc) of 20-44 kg body mass. the dose of 200 mg/kg body mass was too high and there were fatal outcomes only. with the dose of 100 mg/kg and an initial body mass of 30-35 kg it is possible to induce a chronic diabetes mellitus in the pig. as complications we observed intoxications caused by alloxan, hypoglycemic situati ...19826761106
[studies on the prevalence of corynebacterium suis in wild boars and domestic pigs in the federal republic of germany (author's transl)]. 19827044746
the effect of the proline analogue l-azetidine-2-carboxylic acid (laca) on epidermal and dermal wound repair.to evaluate epidermal-dermal interdependency during the wound-healing process, the proline analogue l-azetidine-2-carboxylic acid (laca) was topically applied to split-thickness skin wounds in young domestic pigs. laca is incorporated into collagen and the collagen containing this analogue is extruded from the cell at a decreased rate. wounds were assigned to one of three treatment groups: control (no treatment), laca (0.2 mg in 0.1ml of water), and placebo (0.1 ml of water). on days 2 through 1 ...19827054798
noninvasive measurement of systolic and diastolic blood pressure in swine.arterial blood pressure was measured noninvasively using doppler ultrasound and an occluding cuff. the subjects were 28 domestic pigs (10-49 kg) anesthetized with pentobarbital sodium (25 mg/kg). indirect pressure measurements were made with the doppler unit placed over the radial or the ulnar artery proximal to the carpal joint. comparison was made with directly measured pressure to determine the reliability and reproducibility of the indirect method. direct systolic pressures between 73 and 23 ...19827058906
collagen fibre arrangement in the skin of the pig.the arrangement and proportion of collagen fibres and fibre bundles in the dermis of the pig have been investigated with light microscopical (nomarski's interference contrast, polarization optics) and scanning electron microscopical methods. skin samples were obtained from different body regions of wild boars, domestic pigs and miniature pigs. all the methods used have demonstrated that the bulk of the dermis is dominated by a massive three dimensional network of collagen fibres and fibre bundle ...19827076540
[investigations on the retention period and tolerance of hexabrix as x-ray contrast medium in arthrography (author's transl)].arthrography of the knee joint was performed in 12 domestic pigs using hexabrix (meglumine and sodium ioxaglate). conray ev (sodium and meglumine iothalamate) was used for comparison. x-ray films were taken at periodic intervals. hexabrix was found to stay slightly longer in the joints. the animals were sacrificed at 3 different times after injection and the synovial membrane of the knee joints and the joint cartilage of the patella were assessed histologically. 3 of 6 joints showed a strictly l ...19827079664
fractionation and identification of pig lymph node plasma membrane glycoproteins.plasma membrane vesicles purified from pig mesenteric lymph node tissue were solubilized in 1% (w/v) sodium deoxycholate and the fractionation of both membrane proteins and glycoproteins assessed by gel filtration on aca 34. milligram quantities of the glycoprotein fraction, consisting of 12 distinct bands on sds-page ranging in apparent mol. wt from 12,000 to 250,000, were purified by affinity chromatography on lentil lectin-sepharose. identified among these by specific immunoprecipitation were ...19827099163
morphological studies on the epiphyseal growth plate combined with biochemical and x-ray microprobe analyses.the epiphyseal growth plate of the domestic pig was investigated topologically combining biochemical methods with electron microprobe microanalyses both correlated to histological controls. a lateral resolution of about 50 micrometer was reached. highest nuclease activity was found in the lower columnar cell zone, while alkaline phosphatase showed maximal activity in the hypertrophic area, connected with maximal values for extractable, organically bound phosphorus, and extractable ca and mg. aci ...19827107329
tfi transferrin variant in domestic pig. 19827125302
the effects of antisperm plasma membrane antibodies on sperm-egg binding, penetration, and fertilization in the pig.a procedure using published surgical techniques is described for determining the effects of antiplasma membrane antibodies on sperm-egg binding, penetration, and fertilization in vivo in the domestic pig. time of ovulation was controlled and sperm inseminated at precise times relative to ovulation. sperm were exposed to antibodies (fab) and then washed free of excess antibody and placed in one uterine horn near the uterotubal junction. sperm exposed to control material were placed in the opposit ...19827130938
[are porous tricalcium phosphate ceramics suited for the replacement of bony walls in ear surgery? an animal experiment study of the hypotympanum of the domestic swine].the purpose of this study was to examine the possibility of a partially or totally posterior canal and lateral attic wall reconstruction with a more stable and therefore less porous tricalcium phosphate ceramic plate (s8). the hypotympanon of 4 pigs was drilled out, leaving the bony shell intact. in the middle part of this cavity a 2 mm thick s8-ceramic plate was placed horizontally. the hypotympanon of further 11 pigs was drilled out and obliterated with a more porous tricalcium phosphate ceram ...19827154802
structural studies of purified pig lymph node plasma membrane: association of cytoskeletal compounds with the plasma membrane and the effect of detergent solubilization.the reproducibility of preparation, stability at 4 degrees c, and detergent solubilization characteristics of plasma membrane vesicles purified from domestic pig mesenteric lymph node tissue have been examined. it was found that 2% (w/v) nonidet p-40 solubilized 50-60% and 2% (w/v) sodium deoxycholate solubilized 60-70% of the total membrane protein. as judged by 125i-labelled lentil lectin staining of the sodium dodecyl sulfate--polyacrylamide gel electrophoresis patterns, 2% (w/v) nonidet p-40 ...19827199963
epidemiological studies on the animal reservoir of gambiense sleeping sickness. part iii. characterization of trypanozoon stocks by isoenzymes and sensitivity to human serum.polymorphism in 12 enzymes, as shown by electrophoresis on thin-layer starch-gel, was examined in 88 stocks of trypanosomes of the subgenus trypanozoon isolated from man and animals in the ivory coast and upper volta. three of the enzyme profiles seen in trypanosomes from man in the ivory coast were exactly the same as in trypanosomes from local domestic pigs and from various game animals and a bovine in the upper volta, thus confirming previous evidence that human trypanosomiasis is a zoonosis ...19826287687
hemodynamic measurements after administration of aprotinin and/or heparin during pancreatic cell autotransplantation in the dog, pig, and monkey.transient shock in the form of systemic hypotension and portal venous hypertension has accompanied the portal vein infusion of pancreatic mixed cell autografts in human and canine recipients. the use of aprotinin and/or heparin has been suggested as blocking agents for this vascular reaction. the supernatant from the collagenase-digested pancreatic cells contains the pancreatic shock factor (psf). a total of 45 animals were studied: 15 mongrel dogs, 15 domestic pigs, and 15 rhesus monkeys. femor ...19826175285
characterization of a new alpha-glycoprotein as the major serum component in later fetal and newborn pigs.1. using crossed immunoelectrophoresis, fetuin, alpha-fetoprotein, albumin, transferrin, alpha1-antitrypsin and a fetospecific-like alpha-glycoprotein, were identified as the main serum components in fetal pig (sus scrofa domesticus). 2. fetuin was found to be a trypsin inhibitor, but not a chymotrypsin inhibitor. 3. the fetospecific-like alpha-glycoprotein, not previously reported, accounted for 50% of the total serum proteins in newborn pigs. this protein, however, was a minor component of the ...19826180861
glucagon and tolbutamide as insulin secretagogues in the pig (sus domesticus).1. glucagon tolbutamide, either alone or in combination, were injected i.v. into pigs and the effect upon plasma glucose and insulin concentrations measured. 2. glucagon gave similar insulin responses to those seen in humans, but insulin responses to tolbutamide were less than in humans. 3. combined doses of glucagon and tolbutamide gave similar, though reduced, responses to those seen in humans. at the highest combined doses applied, glucose concentration remained reduced for up to 6 hr. the in ...19826128123
social dominance relationships and spacing behavior of swine.dominance ranks were determined within each of eight pens of domestic swine, susscrofa. data on spacing and orientation of subjects were obtained from 16 mm time-lapse films and 35 mm overhead photographs with the aid of a digitizer assisted fortran program, disangl 2. dominance orders among subjects were relatively linear and stable. no pattern in pen location preferences (fixed space) was found but there were relationships between dominance rank and portable spacing patterns of the subjects. d ...198224895965
fibre types in longissimus dorsi from wild and highly selected pig breeds.longissimus dorsi muscles from six pig breeds were examined histologically. it was found that mean fibre diameter increased with degree of selection in domestic pigs and that the percentage of red fibres decreased-i.e. from mangulica and black slavonian to large white and swedish landrace. the percentage of white fibres showed the reverse tendency whilst that of the intermediate type was not markedly changed. in semi-wild pigs, the percentage of red fibres was still higher and in forest pigs the ...198122054604
on the persistence of human serum resistance and isoenzyme patterns of trypanozoon in experimentally infected pigs.'mini-pigs' were infected with salivarian trypanozoon clones to examine the persistence and stability of the human serum resistance [blood incubation infectivity test (biit)] and isoenzyme characteristics during infection in a new host. a stock regarded as trypanosoma brucei, derived from a domestic pig in the ivory coast, retained its biit negative (serum sensitive), alanine aminotransferase (alat) and peptidase 2 (pep 2) characteristics throughout 343 days of infection in pigs. similarly there ...19816123244
tissue distribution of substance p in the domestic pig during postnatal development. 19816167335
challenge of penicillin-allergic volunteers with penicillin-contaminated meat.in order to obtain information about the clinical course and immunological background of possible allergic reactions due to penicillin-containing food, nine volunteers with penicillin allergy proved by case history, positive skin tests and/or positive penicilloyl-specific rast were exposed to penicillin-contaminated pork. for this purpose a farm pig from an inbred strain received "therapeutic" doses of benzyl procain penicillin before being slaughtered. meat samples were taken from muscle tissue ...19816175241
structure of two subfractions of normal porcine (sus domesticus) serum low-density lipoproteins. x-ray small-angle scattering studies.two subfractions of low-density lipoproteins (ldl) were isolated from normal pig (sus domesticus) serum by a combined method including precipitation, ultracentrifugation, and gel chromatography. the fractions recovered from the buoyant density ranges 1.020-1.050 and 1.050-1.090 g/ml, denoted as ldl1 and ldl2, respectively, were studied with regard to structure and thermotropic behavior by x-ray small-angle scattering and were compared to human serum low-density lipoprotein of density 1.020-1.063 ...19817248280
effects of isoproterenol on the ultrastructure of pig parotid gland.following chronic administration of isoproterenol, the parotid glands of the domestic pig were removed and studied with transmission electron microscopy. acinar cells were markedly altered, whereas ductal elements were apparently unchanged. a notable hypertrophy of golgi membranes was observed. in addition, electron-dense bodies located near the golgi membranes were more numerous after isoproterenol administration.19817257726
[occurrence of exudative (pse) meat consistency in some domestic swine breeds]. 19817258021
elastic fibre arrangement in the skin of the pig.after the removal of collagen and ground substance by autoclaving tissue samples and subsequently applying the sem technique, a dense meshwork of elastic fibres could be demonstrated in the dermis of the pig (wild boar, domestic pig, miniature pig). the abdominal body region showed relatively large amounts of elastic fibres compared to the back and the lateral body wall. in comparison with the papillary layer and the mid-dermis, thicker elastic fibres predominated in the deeper dermis; thinner f ...19817283467
lectin-induced lymphocyte stimulation in pigs--a kinetic study of nors.early reactions of rrna-cistrons in lectin-stimulated pbl cultures of domestic pigs are shown. interphases showing 3 or more clusters of stained areas were attributed mainly to cells after first division. clear differences are shown between pha- and cona-induced nor-expression patterns compared to the patterns in pw-stimulated cultures.19817297648
the nasal cycle in swine.the domestic pig exhibits characteristic fluctuations in nasal mucous membrane congestion and decongestion which meet the stipulated criterion for the existence of a nasal cycle. this phenomenon was documented in 6 of the 11 pigs studied. also, unilateral sympathectomy acutely affects ipsilateral nasal resistance, but this elevated nasal resistance gradually decreases to preoperative values over several weeks. finally, a new technique using active anterior rhinomanometry has been developed which ...19817302471
interfollicular smooth muscle in the skin of the domesticated pig (sus scrofa).an interfollicular smooth muscle that spans the triad of hair follicles has been identified in the skin of the domesticated pig (sus scrofa). this muscle has been previously noted by other investigators and identified as an arrector pili muscle. however, it cannot be interpreted as such for the following reasons: 1) it lies opposite the arrector pili muscle on the follicle; 2) the orientation of its fibers is perpendicular to those of the arrector pili; 3) the two muscles are not continuous; the ...19817305026
experimental atherosclerosis model in domestic pigs. part ii. electrocardiographic and morphologic investigation.experimental atherosclerosis was produced in domestic pigs by administration for 24 weeks a high lipid diet containing cholesterol and coconut oil. ecg changes were not uniform: negative t, prolonged intraventricular conduction, and premature ventricular beats were observed. macroscopic and microscopic anatomo-pathological studies revealed atheromatous changes in the aorta.19817329865
[histometric studies of neurons of selected nuclear regions in the hypothalamic sex centers of swine (sus scrofa domesticus) under various lighting conditions]. 19817337534
a model of experimental atherosclerosis in pigs. part iii. electroretinography and the diameter of retinal vessels.domestic pigs were fed with high lipid diet (hld) for 24 weeks. electroretinographic studies and the measurement of the diameter of retinal arterioles were investigated before and after the administration of hld. the most significant change produced by hld was negativization of electroretinogram. at the same time the diameter of retinal arterioles was significantly decreased.19817347809
[picture documentation of leukemia in domestic swine]. 19817348921
[genetic characteristics of the 1st soviet miniswine minisibs. ii. the immunogenetic characteristics of laboratory minisibs].a laboratory miniature siberian pig "minisibs"--a new laboratory animal in ussr is characterized by a very wide immunogenetic polymorphism for all the blood group systems studied, significantly differing in this respect from all the wild and domestic pigs. when "minisibs" were compared with american, west-german and japanese miniature pigs in relation to the blood group systems e, f, g and l, the considerable distinction was demonstrated. these immunogenetic peculiarities indicate adequately the ...19817197654
periestrous and midluteal time courses of circulating lh, fsh, prolactin, estradiol-17 beta and progesterone in the domestic pig. 19816783133
histological and ultrastructural studies on the pineal gland of castrated male and pregnant female of domestic pig. 19816981549
histology and ultrastructure of the pineal gland in mature female domestic pig. 19816981552
[behavioral reactions of domestic swine to odors]. 19816792826
setaria worms from the domestic pigs in burma. 19816455085
biology of human skin transplanted to the nude mouse: i. response to agents which modify epidermal proliferation.to accept human skin transplanted to the congenitally athymic (nude) mouse as a system to study human skin and its physiologic and pathologic states, it must be demonstrated that skin so maintained retains its function as a biologic unit. we have found that responses of grafted human skin and nude mouse skin to various agents differ. this difference in response has been utilized to assess barrier function and proliferative capacity of human skin grafts. human skin grafts undergo a proliferative ...19817017014
influence of development factors on nutritional patterns in the solomon islands.looks at the general changes brought about by development, and how the nutritional habits of the solomon island communities have been affected by development. the development aspirations of third world countries include the introduction of cash crops for foreign exchange; moving away from subsistence-type economy and self-reliance in feeding one's family to dependence on outside sources; employment of more people at salaried jobs, small industries and factories; and modernization. many governm ...198112265890
retrograde coronary venous perfusion at low pressure.the effectiveness of localized retrograde coronary venous perfusion (rcvp) in preventing or reversing myocardial ischemia after acute ligation of a coronary artery is described. ten domestic pigs (group i) underwent aorto left anterior coronary vein grafting with rcvp at systemic pressure. in another set of ten pigs (group ii), the coronary vein was similarly grafted, but the proximal end of the graft was perfused with oxygenated blood by means of an external pump at reduced pressure and flow. i ...198015216280
effects of peep and of increased frequency of ventilation during cpr.previous reports have attributed increased carotid blood flow to lung ventilation during cpr. this study was undertaken to determine whether peep (20 torr airway pressure) or increased frequency of ventilation (3:1) improved arterial pressure, flow, and blood gases. thirty-three domestic pigs were studied using three protocols (standard 5:1 cpr, 5:1 cpr plus peep, 3:1 cpr) distributed such that comparisons could be made between groups as well as within the same pig. for intrapig comparisons, po2 ...19806988167
ice treatment of injured ligaments: an experimental model.using the radiocarpal ligament of the domestic pig as an experimental model the effects of ice therapy were studied. the results indicate that application of ice causes: (1) increased subcutaneous swelling to injured or uninjured soft tissue; (2) a diminution of histological evidence of inflammation in injured ligamentous tissue.19806928055
retention of fluoride by enamel during maturation in unerupted permanent teeth of the domestic pig. 19806944002
postmeiotic nor-expression during spermiogenesis of the domestic pig (sus scrofa domestica l.). 19806784408
porcine (sus scrofa domestica) chromosome identification and suggested nomenclature.various banding techniques have been used for chromosome analysis in domestic pigs (sus scrofa domestica). the techniques used in karyotype analysis were q-banding by (cma)2s, trypsin-g-banding, brdu-acridine-orange r-banding and c-banding. sequential staining techniques of quinacrine-giemsa were used to record the length of each chromosome and determine arm ratios. sequential quinacrine-giemsa-ag-as treatment was used to locate the nucleolar organizer (nor) on specific chromosomes. a g-c specif ...19807388680
the effects of alinidine, an n-allyl derivative of clonidine, on regional myocardial perfusion and performance in the pig with or without atrial pacing.the effects of alinidine (0.2-6.0 mg . kg-1), an n-allyl derivative of clonidine, were investigated on systemic and regional haemodynamics, in particular myocardial perfusion and performance in the domestic pig, during or in the absence of atrial pacing. the drug had a pronounced bradycardic action and also caused dose-dependent reductions in the maximum rate of rise in left ventricular pressure (max lvdp/dt) cardiac output (co), arterial blood pressure and in the mean velocity of systolic wall ...19807389819
resting metabolism of yucatan miniature swine.oxygen consumption, carbon dioxide production, rectal temperature and skin temperatures were measured in six conscious yucatan miniature swine. heat production was calculated from oxygen consumption and carbon dioxide production data. under ambient conditions (20 degrees c), the parameters studied were similar to what has been reported for conventional domestic swine. during 90 minutes of cold exposure (0 degrees c), oxygen consumption increased by approximately 50%. at 0 degrees c, excessive sh ...19807401619
very low density lipoprotein metabolism in domestic pigs.patterns of triacylglycerol (tg) turnover in plasma and liver, and the hepatic secretion of very density lipoprotein triacylglycerol (vldl tg) into the circulation, have been studied in young large white female pigs, using i.v. tracer [1,3-14c]- and [2-3h]glycerol. serial measurements were made of plasma [14c]glycerol and [14c]glucose and of liver tg and plasma vldl tg specific activities. in other studies vldl tg obtained from a donor pig was reinjected into recipient animals to measure the ear ...19807426088
effect of water and salt intake on pituitary catecholamines in the rat and domestic pig. 19807432631
experimental infection of warthos (phacochoerus aethiopicus) with african swine fever virus.although there were no obvious signs of illness following experimental infection of young warthog with african swine fever virus, the animals developed viraemias between 10(2,4) and 10(3,6) hd50/ml within the first week of infection, and virus concentrations in a number of lymphatic tissues attained high levels (greater than or equal to 10(6) hd50/g). unlike in blood, and to some extent in the spleen, virus titres in lymph nodes did not decline appreciable during the 33-day observation period, s ...19807454231
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