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comparative neuromuscular blocking effects of vecuronium, pancuronium, org 6368 and suxamethonium in the anaesthetized domestic pig.the neuromuscular blocking and cardiovascular effects of three competitive neuromuscular blocking drugs, vecuronium, pancuronium and org 6368, and the depolarizing drug suxamethonium, have been evaluated in the anaesthetized domestic pig. both the relative time-course and the order of potency of the drugs agreed well with published data in man. in addition, the cardiovascular side-effects of pancuronium and org 6368 were identified readily. these preliminary results suggest that the pig may prov ...19872883986
trichinella spiralis: genetic evidence for synanthropic subspecies in sylvatic hosts.isolates of the nematode genus trichinella from sylvatic hosts differ in their potential to reproduce in domestic swine. the structure of the genomic dna from 13 sylvatic isolates from north america and 5 pig isolates, 4 from north america and 1 from asia, was examined and correlated with the infectivity of the isolate for domestic pigs. dna restriction fragment length differences, identified by ethidium bromide staining and by hybridization with 32p-labeled ribosomal rna, served as molecular ma ...19872888683
antibodies to vesicular stomatitis new jersey type virus in wild and domestic sentinel swine.wild sentinel swine on ossabaw island, chatham county, georgia, were serially bled and tested for vesicular stomatitis new jersey type virus neutralizing antibody to determine the intensity, distribution, and progression of annual viral activity. from march through september, 1984 and 1985, 112 and 226 juvenile (less than 8 months) swine, respectively, were sampled. seroconversions initially were detected on may 7, 1984 and may 18, 1985. incidence of seroconversion in wild swine reached 32% duri ...19873034056
the effect of intraosseous sodium bicarbonate on bone in swine.five domestic swine weighing 8 to 12 kg were anesthetized with ketamine 20 mg/kg im and pentobarbital 20 mg/kg iv. after a sterile prep each animal received nahco3 1 meq/ml/kg in one tibia and saline 1 ml/kg in the other. the animals were allowed to recover and were observed for 30 days. at the end of this period, roentgenographs were obtained of each tibia and triple phase 99m technetium bone scans were obtained. the tibias also were sectioned, stained, and examined under light microscopy for m ...19873035967
[adaptation of a natural strain of trichinella to domestic swine]. 19872960875
[experimental biological research on dental filling materials in an application test on domestic swine]. 19872961163
tendons: high-field-strength, surface coil mr imaging.high-resolution magnetic resonance (mr) images of the tendons of the hands, wrists, feet, and ankles of six healthy volunteers and six cadavers were obtained using receive-only surface coils and reduced-field-of-view imaging. normal anatomy was identified and compared with gross anatomic sections of the six cadavers. experimentally produced tears of the calcaneal (achilles) tendon in domestic swine were identified on mr images. the hands and feet of 11 patients were examined, and a variety of pa ...19873809487
domestic pigs as sentinels to monitor the activity of japanese encephalitis & west nile viruses in kolar district, karnataka. 19872832323
distribution of the antibody to influenza c virus in dogs and pigs in yamagata prefecture, japan.the distribution of the antibody to influenza c virus in the dogs and pigs in yamagata prefecture, japan was investigated by using three different serological methods: hemagglutination-inhibition (hi), radioimmunoprecipitation (rip), and immunoblotting. the antibody against influenza c virus glycoprotein (gp88) was detected in 5 out of 112 sera collected from mongrel dogs, three by rip test and two by any of the three methods, suggesting that the virus can cause natural infection in dogs. signif ...19872836710
electrophoretic polymorphism of erythrocyte leucine aminopeptidase in the wild boar, sus scrofa.an erythrocyte leucine aminopeptidase (rbc lap) electrophoretic polymorphism was detected in italian wild boars, sus scrofa. such a polymorphism has not previously been reported in the domestic pig. it is suggested that this locus could be a marker for genetic differences between the domestic and the wild forms of sus scrofa.19863826759
protective immunity to ascaris suum: analysis of swine peripheral blood cell subsets using monoclonal antibodies and flow cytometry.outbred domestic swine or sla inbred miniature swine were exposed to ascaris suum either naturally on contaminated lots or by inoculation with uv-irradiated attenuated eggs. both inbred and outbred swine developed virtually complete protection to a challenge of 10 000 eggs after natural exposure, but inbred swine were less resistant than outbred swine after uv-egg exposure. flow cytometric analysis of peripheral blood mononuclear cells from these animals, performed to determine changes in cell s ...19862939618
strain-specific 1.7 kilobase repetitive deoxyribonucleic acid sequence family in trichinella spiralis.eco ri digestion of bulk dna from trichinella spiralis p1, an isolate from domestic pig, reveals the presence of families of repetitive sequences. one of the most prominent of these has a monomer size of 1.7 kb, which exists in minimally dispersed direct tandem arrays, with a copy number of about 2800, and represents 2% of the genome. although there is evidence that the eco ri site is missing in some of the family members and that a 1.9 kb variant of the sequence also occurs, the family is highl ...19863027555
assignment of the major histocompatibility complex to the p1.4----q1.2 region of chromosome 7 in the pig (sus scrofa domestica l.) by in situ hybridization.the pig major histocompatibility complex (sla) was mapped by in situ hybridization. the probe used was a human cdna containing most of the coding sequence for hla-b7. the sla complex was localized to the region p1.4----q1.2 on chromosome 7.19863082605
similar epidermal changes in hyperkeratotic scabies of humans and pigs.we compared some morphological and biochemical aspects of the epidermal changes occurring in hyperkeratotic scabies in humans and domestic pigs. clinically and histologically, pig skin alterations look very similar to those observed in humans, i.e., brittle hyperkeratosis with parakeratotic crusting and thickening of the epidermis. parakeratosis seems to correspond to previous passage of scabies mites through the incompletely differentiated layers of the epidermis. indeed, by serial sectioning w ...19862425653
conservation of diagnostic antigen epitopes among biologically diverse isolates of trichinella spiralis.crude and immunoaffinity-purified excretory-secretory antigens derived from a domestic pig isolate of trichinella spiralis were used in an enzyme-linked immunosorbent assay to test serum from mice infected with 25 different pig and wild animal isolates of t. spiralis sspp. all of the sera were found positive by elisa using either of the antigen preparations, indicating all isolates shared certain antigen epitopes. excretory-secretory antigens were prepared from 3 distinct isolates of t. spiralis ...19862434638
[effect of iloprost on aggregation behavior in kidney conditioning and changes in iloprost concentration in kidney preservation].the conditioning of the donor by 1.0 microgram/kg x min iloprost over 15 minutes leads to a considerable inhibition of the aggregation of thrombocytes in the domestic pig. 160% more adp had to be added than before the application of iloprost. when 0.5 microgram/ml iloprost are added to the perfusion fluid and to the reperfusion fluid 0.22 microgram/ml and 0.27 microgram/ml, respectively, are to be proved in the venous efflux. whether or not the difference is absorbed or metabolized must remain o ...19862437731
a preliminary comparison of trypanosoma simiae and t. congolense by isoenzyme electrophoresis.trypanosoma simiae, although similar to t. congolense in morphology and mode of development in the tsetse vector, is regarded as a separate species mainly because it is highly pathogenic to the domestic pig and fails to infect rodents. to establish whether the two species are distinct biochemically, we compared by isoenzyme electrophoresis 2 isolates of t. simiae with 7 stocks of t. congolense, together with one of t. brucei. all isoenzyme patterns of the 6 enzymes examined differed in t. simiae ...19862872783
trypanosoma brucei infection in domestic pigs in a sleeping sickness epidemic area of uganda. short communication. 19862874715
production and evaluation of specific antisera against sera of various vertebrate species for identification of bloodmeals of glossina morsitans centralis.specific antisera against sera of 46 species of vertebrates were prepared. the antisera to 21 bovidae species were raised in goats except the antiserum to goat serum which was raised in sheep. the antisera to 3 suidae species were produced either in domestic pigs or warthogs, while antisera to most of the other vertebrate species were raised in rabbits. the antisera were used in an enzyme-linked immunosorbent assay (elisa) to identify the source of bloodmeals ingested by teneral and non-teneral ...19862882665
[periodontal diseases in domestic swine]. 19863467471
gross anatomy of the mandibular joint and masticatory muscles in the domestic pig (sus scrofa).the mandibular joint (mj) and masticatory muscles in 15 domestic pigs, aged 1 year, were investigated during and after dissection. the joint consisted of a fossa, disc and condyle surrounded by a ligamentous capsule. the fossa was almost flat, slightly convex antero-posteriorly and concave medio-laterally; the disc was biconcave and the condyle oval. the long axis of the condyles formed an anteriorly orientated angle to the frontal plane. the masticatory muscles were similar to human ones except ...19863479064
[treatment of sarcoptic mange in wild and domestic swine with ivermectin (ivomec)]. 19863536415
prostacyclin and thromboxane a2 in septic shock: species differences.prostacyclin and thromboxane a2 have been implicated as mediators of septic shock. correlations between the human prostanoid response to sepsis and experimental paradigms are poorly understood. the purpose of this study was to compare changes in plasma levels of prostaglandin 6-keto-f1 alpha (pgi) and thromboxane b2 (txb) during septic shock in sprague-dawley rats, domestic pigs, mongrel dogs, and man. severe sepsis followed by septic shock (systolic bp less than 90 mmhg) was induced in rats by ...19863539388
morphological characteristics of the gyrus dentatus in some animal species and in man.comparative anatomical investigations have been carried out on the gyrus dentatus of rat, fox, cattle, domestic pig, monkey (cercopithecus sabeus) and man. after removal of the brain stem and scaling off the brain substance from the medial aspect towards the lateral aspect, the gyrus dentatus was preserved and its relation with regard to the hippocampus, the fimbria hippocampi and the gyrus parahippocampalis was studied. a rat's gyrus dentatus occupies a rather wide zone on the medial aspect of ...19863717598
porcine coccidia in papua new guinea.faecal samples from 232 domestic pigs raised on concrete, 98 free-ranging village pigs, and five wild boar showed 46.6 (108/232), 54 (53/98) and 80% (4/5) prevalence of coccidian oocysts, respectively. eight species of eimeria, and isospora suis, were recovered. in their descending order of predominance in the pigs raised on concrete, the species of coccidia were e. debliecki (26.7%), e. scabra (22.4%), e. neodebliecki (19.8%), e. porci (15.5%), e. suis (11.6%), e. polita (8.6%), e. perminuta (7 ...19863727342
chromosomal localization of leukocyte interferon gene in the pig (sus scrofa domestica l.) by in situ hybridization.using as a probe pig genomic dna, including the complete interferon alpha gene, we have mapped the leukocyte interferon gene on pig chromosome 1 by in situ hybridization. a total of 196 silver grains were noted on the 106 metaphases scored: 31% of the grains were observed on chromosome 1, and 67% of these were localized in the region 1q2.2----q2.7.19863731881
[individual variability and inheritance of the number and size of the nucleolar organizer regions in chromosomes of domestic swine].individual variability of the number and size of silver-staining nucleolar organiser regions (nor) was studied in 76 pigs of semirechenskaya, big white and duroc breeds. the variability of the nor number is exclusively caused by the presence of the 8nor- allele (the chromosomes of the 8th homologous pair lacking the silver-staining nor). concentration of the 8nor- allele is about 0.7 in the average for all three breeds. all 7 offsprings from the homozygous parents male 8nor- /8nor- and female 8n ...19863732795
polygraphic analysis of the sleep-wake states and the rem sleep periodicity in domesticated pigs (sus scrofa).electrocorticography and concurrent electromyography were used during a total of nineteen 24 hr periods in three juvenile pigs in order to establish the quantitative duration of the sleep-wake states and the rem sleep cycles. wakefulness (w), drowsiness (dr), slow-wave sleep (sws) and paradoxical sleep (rem) occupied respectively 46.5%, 15.9%, 26.7% and 10.9% of the 24 hr period. mean duration of episodes was 4.1 min for dr, 6.2 min for sws and 3.3 min for rem. sleep cycles (sc) duration was 13. ...19863737741
[unsaturated fatty acids in the lipids of the spermatozoa of ovis amon aries l. and sus scrofa domestica l].spectrophotometric investigations were carried out with five unsaturated fatty acids found in the composition of spermatozoid lipids of animals belonging to four breeds of ovis amon aries l. parallel comparative analysis were made of the fatty acids in the lipids extracted from spermatozoa of landrace swine of the sus scrofa domestica l. species. differences were established as to the percent content of fatty acids, having low points of freezing. it is believed that the criterion of cold resista ...19863765375
the analgesic effect of buprenorphine, etorphine and pethidine in the pig: a randomized double blind cross-over study.in order to find a suitable analgesic for the treatment of postoperative pain in pigs the analgesic effect of buprenorphine, etorphine and pethidine has been compared in 8 domestic pigs. for assessment of the analgesic action on thermal (hot plate) and two mechanical (cannulation of ear vein, needle prick) noxious stimuli have been employed. in a pilot experiment on 2 pigs in which methadone was included the maximal effective doses were estimated for each drug. methadone was found unsuitable bec ...19863766147
povidone-iodine in polyethylene oxide hydrogel dressing. effect on multiplication of staphylococcus aureus in partial-thickness wounds.we studied the ability of a polyethylene oxide hydrogel dressing (vigilon) containing povidone-iodine to prevent staphylococcus aureus proliferation in partial-thickness wounds. we previously reported that a single application of povidone-iodine on wounds challenged with 2 x 10(6) s aureus was not effective in reducing the number of s aureus after 24 hours. it was therefore hypothesized that povidone-iodine might be effective if it was available continuously and applied to wounds containing a sm ...19863767400
effect of a reduction in blood viscosity on maximal myocardial oxygen delivery distal to a moderate coronary stenosis.this study tested the hypothesis that a reduction in blood viscosity by means of isovolumetric hemodilution will permit an increase in maximal oxygen delivery to myocardium distal to a moderate coronary arterial stenosis. it is known that blood viscosity is a determinant of resistance to blood flow at both the stenotic and the arteriolar levels. accordingly, a reduction in blood viscosity could exert a favorable influence on maximal myocardial oxygen delivery in the setting of stenosis, provided ...19863769166
the pig as a model for myocardial ischemia and exercise.the pig has been well characterized as an appropriate model for the study of coronary physiology, the coronary collateral circulation and exercise physiology. we compared both yucatan miniature swine and young farm pigs in experiments involving myocardial ischemia, infarction and exercise. the yucatan pig was vigorous, docile and proved to be an appropriate model of coronary physiology and exercise in man. the exercise capacity of the yucatan pig was greater than that of the similar weight hamps ...19863773444
long-acting intramuscular anesthetic regimen for swine.a two-stage, long-acting, injectable anesthetic regimen which provided pain-free restraint for swine was developed using nine mixed-breed domestic pigs. each animal was administered a first-stage drug combination consisting of meperidine hydrochloride and azaperone in the caudal thigh muscles, followed after 20 minutes by a second-stage group of injections consisting of ketamine hydrochloride combined with morphine sulfate in the same muscles of the opposite leg. a mean surgical anesthetic time ...19863773452
serum biochemistry of healthy yucatan miniature pigs.sera collected from 24 (12 boars and 12 gilts) healthy, fasted 28-43 week-old yucatan miniature pigs were analyzed for 21 clinical chemistry parameters. the mean, standard deviation, median, and observed range for each parameter are presented as reference values for the normal blood chemistry for this breed. comparison with published values reveals that the yucatan miniature pig has a blood chemistry profile comparable to that of domestic pigs and other breeds of miniature swine.19863773456
role of adenosine in mediating myocardial blood flow response to isoproterenol: observations in closed chest, sedated, domestic swine.to test the hypothesis that adenosine is required to mediate the sustained increase in myocardial flow evoked by isoproterenol haemodynamic indices, myocardial blood flow (microspheres), and regional myocardial oxygen consumption were measured in eight closed chest, sedated pigs at control, after isoproterenol (6.9(2.8) ng x kg-1 x min-1 (mean (sd)) infused into the left anterior descending coronary artery, repeat control, and after a simultaneous infusion of the same dose of isoproterenol and a ...19863779747
pig beta-lactoglobulin i (sus scrofa domestica, artiodactyla). the primary structure of the major component.beta-lactoglobulins from pooled milk (sus scrofa domestica) are isolated and characterized. the complete primary structure of the major beta-lactoglobulin component i is presented. the amino-acid sequence was elucidated by automated edman degradation of tryptic peptides and cyanogen bromide cleavage products in a liquid phase sequencer. the tryptic and cyanogen bromide peptides were separated by reverse-phase (rp-2) or size exclusion (tsk 2000 sw) high performance liquid chromatography. pig beta ...19863790256
storage of pathogenic leptospires in liquid nitrogen.the virulence and viability of various serovars of leptospira interrogans were successfully preserved by storage in liquid nitrogen. dimethyl sulphoxide at a final concentration of 2.5% (v/v) was added as cryoprotectant to a culture of leptospires grown in ellinghausen-mccullough-johnson-harris medium. ampoules were cooled at a controlled rate of 1 degree-3 degrees c/min to -70 degrees c, then transferred to the liquid phase of a liquid nitrogen storage unit. glycerol was discounted as a cryopro ...19863804861
[epidemiologic survey of the cysticercosis endemic on réunion island].the high incidence of cysticercosis was underestimated in reunion island before computed tomography (january, 1984). in 1974, soulayrolles et boyer-vidal found that cysticercosis was responsible for 0.5 p. 100 of the cases of epilepsy. in hospitalized people, routine cranial and muscles radiographies detected: 1/among 242 epileptics: 183 men: 36 positive (19.67 p. 100); 59 women: 9 positive (15.25 p. 100), 2/among 166 non epileptic-related neurological disorders: 106 men, 6 positive (5.66 p. 100 ...19863797934
comparison of experimental hypercholesterolemia and atherosclerosis in göttingen mini-pigs and swedish domestic swine.mini-pigs of the göttingen strain and domestic swine of the swedish landrace were compared with respect to their susceptibility to alimentary hypercholesterolemia and experimental atherosclerosis. hypercholesterolemia was produced in both strains by adding 11.2% egg yolk and 0.5% cholesterol to the diet. the plasma cholesterol rose significantly faster and reached a higher level in the mini-pigs than in the domestic swine. in both strains most of the elevated plasma cholesterol was found in the ...19863964345
regeneration of epidermis by cells grown in tissue culture.pig epidermal cells were grown in vitro for 21 to 180 days, forming multilayered sheets of epidermis varying from thirteen to forty layers. for an evaluation of their use in wound coverage, they were transplanted onto surgically prepared full-thickness wound beds on domestic swine. autologous epidermal cells were studied on twenty-five of the animals, and allogeneic epidermal cells were studied on thirteen. autologous epidermal cells grown in vitro provided functional wound coverage 10 to 15 day ...19853973141
effects of calcium entry blockers on coronary constriction and myocardial ischemia due to leukotriene d4.recent studies show that leukotrienes (lts) produce profound coronary artery constriction. although calcium entry blockers are commonly used to remedy coronary vasospasm, their capacity to interfere with lt-mediated coronary constriction is unknown. therefore, we compared effects of intracoronary ltd4 before and during treatment with calcium entry blockers in the in situ, blood-perfused hearts of domestic pigs. intravenous administration of verapamil (0.1-1.6 mg/kg), nifedipine (10 or 100 microg ...19853981457
notes on placentation in the suina.we examined the gross and microscopic anatomy of placental tissues and umbilical cords from six species representing the three living families of the suina. these species included, of the suidae, the wart hog (phacochoerus aethiopicus), the giant forest hog (hylochoerus meinertzhageni), the domestic pig (sus scrofa), and the banded pig of malaysia (sus scrofa vittatus); of the tayassuidae, the white-lipped peccary (tayassu pecari); of the hippopotamidae, the hippopotamus (hippopotamus amphibius) ...19853991477
group r streptococci: wild boars as a second reservoir.group r streptococci have caused many cases of septicaemia and meningitis in patients handling live or slaughtered pigs which were the only known reservoir of group r streptococci. a human case, due to a wild boar, is reported here and it is therefore concluded that there exist both a domestic (pig) and a wild (wild boar) reservoir of group r streptococci.19853992197
trichinella spiralis: acquired immunity in swine.the ability of domestic pigs to develop protective immunity to trichinella spiralis in response to inoculation with different doses of muscle larvae was assessed. adult worms developing from the inoculations of 112, 500, and 10,000 larvae were expelled from the intestine about 6 weeks after inoculation. inoculation with 25,000 larvae, however, resulted in more rapid intestinal worms expulsion, indicating that gut expulsion is dose dependent. secondary expulsion also tended to be dependent upon p ...19853996525
comparison of lung antioxidant levels in humans and laboratory animals.basal lung concentrations of ascorbic acid (aa), nonprotein sulfhydryls (npsh), and alpha-tocopherol (alpha-t) were determined in rabbits, guinea pigs, rats, hamsters, mice, domestic pigs and sheep, and in human lung samples obtained from cancer surgery patients. significant differences were found among the laboratory animals: aa levels ranged from 25.6 mg% (mg/100 g wet weight) in hamsters to 41.7 mg% in mice, npsh from 50.9 mg% in rats to 84.7 mg% in rabbits, and alpha-t from 1.01 mg% in hamst ...19854003918
histologic and temperature alterations induced by skin refrigerants.the histologic alterations induced by spray refrigerants independent of and in combination with dermabrasion were studied with the use of the domestic pig as a model. tissue injury was found to be a function of spray duration and freeze intensity. both preabrasion freezing and postabrasion refreezing could produce damage additive to that of mechanical planing. skin surface and intradermal temperature variations during refrigeration were recorded. the possible implications of these findings as th ...19854008684
peripheral plasma prolactin concentrations during oestrous cycles in different types of primitive gilt.plasma prolactin concentrations were determined by radioimmunoassay during oestrous cycles and around the time of oestrus in different types of primitive gilts: vietnamese, zlotnicka and wild-boar x domestic pig hybrids. the animals were bled without stress from an indwelling arterial catheter. the following results were obtained: (1) in all gilts the main prolactin peak was observed at day 15 or 16 of the oestrous cycle; (2) vietnamese and hybrid gilts showed a second smaller prolactin surge af ...19854038515
assignment of the porcine major histocompatibility complex to chromosome 7 by in situ hybridization.the major histocompatibility complex (sla) of the domestic pig (sus scrofa) was regionally mapped to 7p12----q12 by in situ hybridization with an sla class i-specific recombinant dna probe. this localization contradicts linkage data suggesting a possible assignment of the sla locus to porcine chromosome 15.19854042688
topical chemotherapy of intradermal walker 256 carcinosarcoma with diaziquone and doxorubicin in the rat.a model for metastatic skin cancer using intradermal injection of walker 256 carcinosarcoma has been developed in the rat. using this model, antitumor activity of topically applied doxorubicin and diaziquone in vanicream, plastibase, and dimethyl sulfoxide (dmso) as vehicles was compared with intraperitoneal injection of the drugs at the same doses beginning 4 days after injection of tumor cells. doxorubicin applied topically at 0.5 mg/day for 4 days in vanicream or plastibase exhibited no antit ...19854053022
effects of different-shaped tissue expanders on transluminal pressure, oxygen tension, histopathologic changes, and skin expansion in pigs.this study, performed on domestic pigs, was designed to show whether the shape and size of a tissue expander influences the amount of surface area increase. when a defect is irregular, a larger custom-fitted implant is more efficient than several smaller expanders. oval implants gained 5 percent more skin using 50 percent less time and almost 20 percent less intraluminal pressure, while u-shaped implants yield 2.2 percent more skin in 10 percent less time with 35 to 50 percent less pressure when ...19854059413
reperfusion before global ischemic arrest improves the salvage of infarcting myocardium.to study the effect of hypothermic global ischemic arrest on an evolving myocardial infarction and of perfusion of the ischemic zone or region at risk before global ischemia, 62 farm pigs underwent 15, 30, or 60 minutes of reversible coronary occlusion. twenty-eight of these animals served as controls: reflow to the region at risk was established by removal of the coronary occluder without the addition of global ischemia. another 26 animals had similar periods of coronary occlusion and then were ...19854062403
a four-year survey of african swine fever in malawi.a serological survey of free-ranging domestic pigs in the central and southern regions of malawi, together with laboratory data on confirmed cases of african swine fever (asf) and data from interviews with pig owners, undertaken over a four-year period from 1981-4, has enabled the asf enzootic area of malawi to be identified. the area covers much of the western part of the central region and includes mchinji district and parts of kasungu, ntchisi, dowa and lilongwe districts. mortality is substa ...19854067292
[effect of sodium selenite on the course of acute experimental myocardial infarct].the effect of sodium selenite on experimental myocardial infarction was investigated in 47 domestic pigs, with a major emphasis on the hemodynamic antiarrhythmic effects of selenium. intravenous sodium selenite administered in a dose of 1-2 mg/kg body weight produced a favorable pharmacologic effect. the hemodynamic action consisted in an increase of heart rate, and the maximum aortic flow rate, cardiac output, minute volume of the heart and coronary flow, as well as a decrease in total peripher ...19854079230
[mathematical formulations of the fetal mass growth in cattle].after a short review of investigations into fetal weight growth of cattle, the first mathematical treatment of values gained by swett and collaborators (1948) and approximated by simple power functions after a proposal from bereskin and touchberry (1967) is recalled. thereafter values for the weight of fetus and uterus with content as summarized by huth (1962) are approximated with growth functions applying nonlinear regressions. the 6 functions taken into consideration range from classical to q ...19854096405
detecting arterial and venous obstruction in flaps.island skin flaps based on the latissimus dorsi muscle were raised in domestic pigs. flap circulation, maintained only by the vascular pedicle, was monitored by laser doppler flowmetry, laser photometry, and transcutaneously measured carbon dioxide tension. both arterial and venous occlusion were accompanied by very low laser doppler flow values. in laser photometry, the backscattered intensity of light remained unchanged or was slightly increased during arterial occlusion. in response to venous ...19853156550
effects of platelet-activating factor on coronary hemodynamics and coronary venous plasma levels of txb2, 6-keto-pgf1 alpha, and leukotriene c4 immunoreactivity in the intact domestic pig heart. 19853159202
streptozotocin diabetes in juvenile pigs. evaluation of an experimental model.spontaneous diabetes in the domestic pig, an animal suitable for metabolic and endocrine studies and for experimental surgery, is extremely rare. in this study we have compared the diabetogenic response of various doses of streptozotocin in comparison to surgically induced diabetes. streptozotocin in a low dose, 35 mg/kg body weight did not influence glucose metabolism while an intermediate dose, 85 mg/kg, resulted in a transient diabetic reaction. streptozotocin, 100-150 mg/kg body weight, caus ...19853160643
ultrastructure of the integument of the domestic pig (sus scrofa) from one through fourteen weeks of age. 19853161419
ultrastructure and topography of dense bodies in pinealocytes of castrated males of domestic pig. 19853836180
pharmacokinetics of chronic fluoride ingestion in growing pigs.the present study was undertaken to estimate bio-availability and biological half-life of fluoride and accumulation of fluoride in bone in the domestic pig. eight animals receiving 2 mg f-/kg b.w. per day from age 8 to 14 months were compared with eight controls. plasma fluoride concentrations just prior to the daily oral dose were measured at regular intervals. after 112 days post-dose, plasma fluoride levels were measured over a 48-hour period following the daily oral dose or a single intraven ...19853855893
[genetic and functional effects on fiber type composition and fiber diameters in the longissimus muscle of the thorax and the semitendinous muscle of swine. studies of exercised domestic swine and wild swine kept under restricted mobility]. 19853886351
lipid transport systems: some recent aspects in swine, cattle and trout during development.lipids such as triacylglycerols, free and esterified cholesterol and phospholipids are essentially insoluble in water; lipoproteins, which are complex macromolecules of pseudomicellar structure, have evolved to ensure their efficient transport in the vascular system of vertebrates. plasma lipoproteins are operationally classified according to their relative lipid and protein contents and thus according to density. the protein components, i.e. apolipoproteins, have a highly specialized structure ...19853887526
nucleoside transport and metabolism in erythrocytes from the yucatan miniature pig. evidence that inosine functions as an in vivo energy substrate.erythrocytes from the yucatan miniature pig, like those from the normal domestic pig, lack functional glucose transporters and were unable to utilize plasma glucose as an energy source. in contrast, inosine and adenosine entered the cells rapidly. the nucleoside transporter responsible for this uptake was identified as a band 4.5 polypeptide (5000 copies per cell; apparent mr 45 000-66 000). inosine concentrations in the physiological plasma range (1.6-2.5 microm) were found to maintain normal e ...19853902093
[animal experiment studies on the healing of bone transplants by clamping plate fixation following hyperthermic denaturation].the re-use of resident bone transplants after hyperthermic denaturalization is demonstrated in radiologically, clinically, and histologically in the lower jaw of the domestic pig. periosteal and enosteal osteogenic effect is induced.19853909673
influence of light and photoperiodicity on pig prolificacy.in the wild pig mating activity is seasonal. the main breeding period is in late autumn but a second period may occur around april. it is known from other species that seasonal variations in breeding activity are mainly regulated by photoperiod. in the domestic pig seasonal influences on prolificacy still exist: for example, ai boars not only show decreased steroid synthesis, sperm counts and libido in summer compared with the optima which occur in winter but also a biphasic pattern with a trans ...19853910824
the epidemiology of african swine fever: the role of free-living hosts in africa.the known distribution of african swine fever (asf) virus in africa is reviewed in relation to the distributions of its free-living hosts as are the infection rates of these species in different localities in southern africa. mechanisms by which asf virus is maintained in its sylvatic state and ways in which the infection may enter domestic pig populations are discussed.19853911134
[in vitro oxidation of [u-14c] palmitate, [1-14c] and [6-14c] glucose in newborn and adult rats and pigs].studies have been made on the intensity of oxidation of [u-14c]-palmitate, [1-14c]- and [6-14c]-glucose by slices of the liver and skeletal muscles of new-born, 1-day, 5-day and adult wistar rats and domestic pigs. it was found that the level of 14co2 production from these substrates is higher in tissues of rats than in those of pigs. at early stages of ontogenesis, in tissues of both species intensive oxidation of glucose is observed together with oxidation of fatty acids. in the course of onto ...19853920843
measurement by electrical impedance aggregometry of porcine platelets response to selected physiological agonists.although the domestic swine is commonly employed for physiological studies of the coronary circulation, there is relatively little data available concerning the responsiveness in whole blood of normal porcine platelets to standard physiological agonists. such information is essential if the domestic swine is to be used as an animal model for studying potential interactions between platelets and the coronary circulation. accordingly, the present study was undertaken to characterize the responses ...19853923491
chromosome mapping in domestic pigs (sus scrofa): mpi and np located to chromosome 7. 19853930426
chromosome mapping in domestic pigs (sus scrofa): pk is not linked to the syntenic group mpi-np on chromosome no. 7. 19853930427
the oxygen affinity of mammalian hemoglobins in the absence of 2,3-diphosphoglycerate in relation to body weight.we studied the oxygenation of mammalian hemoglobins: mouse (mus musculus molossinus), rabbit (oryctolagus cuniculus domesticus), japanese monkey (macaca fuscata), man (homo sapiens), sheep (ovis aries), llama (lama glama), pig (sus scrofa domesticus), cow (bos taurus domesticus) and horse (equus caballus), in the absence of 2,3-diphosphoglycerate (dpg) and compared their oxygen affinity in relation to the body weight. the negative correlation between body weight and the oxygen affinity of the wh ...19852866879
ontogeny of neuropeptidergic systems: luteinizing hormone releasing hormone (lhrh); somatostatin (srif) and neurophysin (nf) in the hypothalamus of the domestic pig by immunocytochemistry.the ontogenic development of some hypothalamic neuropeptides: luteinizing hormone releasing hormone (lhrh); somatostatin (srif) and neurophysin (nf) and their localization in the hypothalamus of fetuses in different stages of the fetal life were studied by immunoperoxidase method. it was found that differentiation of the neurons which produce the examined hormones begins in the midstage of pregnancy. lhrh is stored in the nerve terminals of the median eminence (me) and organum vasculosum of the ...19852867938
comparison of intraosseous, central, and peripheral routes of sodium bicarbonate administration during cpr in pigs.obtaining venous access continues to be one of the most difficult problems faced by a physician caring for the pediatric patient in cardiac arrest. our study examined the use of the intraosseous route (through the bone) to obtain venous access for sodium bicarbonate administration in a cardiac arrest model. ventricular fibrillation was induced in 23 domestic swine. cardiopulmonary resuscitation was performed for five minutes and sodium bicarbonate (1 meq/kg) was administered through a peripheral ...19852998236
substance k: vascular and cardiac effects in rat and pig.the effects of substance k (sk), a newly discovered tachykinin, on the cardiovascular and sympathetic system were evaluated in the pithed rat preparation and in the in situ domestic pig heart. in pithed rats, sk (10 nmol/kg, iv) produced a triphasic mean blood pressure (map) response: short depressor, short pressor (+11 +/- 1 mmhg), and prolonged depressor phase (-9 +/- 1 mmhg, n = 9-24, p less than 0.001). neither effect was significantly affected by pretreatment with propranolol (2 mg/kg) or p ...19853001674
detecting changes of arterial and venous blood flow in flaps.island skin flaps based on the latissimus dorsi muscle were raised in domestic pigs. simultaneous recordings of laser doppler flowmetric and laser photometric values were made on the skin in the middle of the flap. occlusion of either the artery or the vein of the pedicle was accompanied by very low laser doppler flow values. in laser photometry the total intensity of backscattered light remained unchanged or was sightly increased during arterial occlusion. in response to venous occlusion, howev ...19852935062
endoscopic treatment of bronchus stump fistulae following pneumonectomy with fibrin sealant in domestic pigs.occlusion of the transected bronchus after pneumonectomy was achieved by transthoracic fibrin sealing in 14 domestic pigs. in 9 additional animals standardized bronchus stump fistulae could also be closed with fibrin sealant which was applied through a flexible bronchoscope. an average of 1 ml of fibrin sealant containing 500 units of thrombin and 3500 units of aprotinin was necessary to achieve bronchial closure and to prevent early dissolution of the sealant. endoscopic closure of a bronchus f ...19852417369
control of epidermal cell proliferation in vitro.epidermis from explants of keratome slices of domestic pig skin can be induced to migrate, proliferate, and stratify if at least two serum protein factors and a source of nucleosides are present. the factor which is necessary for cell movement or spreading is destroyed by heating the serum to 100 degrees c and is resistant to 80 degrees c heating. this factor has a molecular weight of 65,000 and is identical to the 'epibolin' found by stenn. proliferation is dependent on a serum factor which is ...19846204674
proteins in the amniotic and allantoic fluids of fetal pigs.seven proteins were identified in the amniotic and allantoic fluids of fetal pigs (sus scrofa domesticus) using crossed immunoelectrophoresis: albumin, fetuin, transferrin, alpha-fetoprotein (afp), alpha 1-acid glycoprotein, alpha 1-antitrypsin and alpha 2-macroglobulin. the total protein concentrations were determined by the method of bradford and individual protein concentrations by radial immunodiffusion or rocket immunoelectrophoresis. transferrin and fetuin were the major proteins in amniot ...19846206980
effect of topically applied steroidal and nonsteroidal anti-inflammatory agents on skin repair and regeneration.we studied the effects of topically applied steroidal and nonsteroidal anti-inflammatory agents on dermal and epidermal wound healing. superficial wounds (0.3 mm deep) on the skin of domestic pigs were treated daily with either 0.1% triamcinolone acetonide (ta), 1% hydrocortisone (hc), 1% nandrolone decanoate (nd), 1% nd + 0.1% ta, 10 mg ibuprofen, 10 mg meclofenamate sodium, 3 mg indomethacin, vehicle (usp petrolatum or 70% ethanol), or control (untreated). wounds were excised on days 2-7 after ...19846207052
physiologic concentrations of cortisol suppress cell-mediated immune events in the domestic pig.mild restraint of the domestic pig (sus scrofa) caused activation of the hypothalamic-pituitary-adrenal axis, atrophy of the thymus gland, and a significant reduction in cell-mediated, delayed-type hypersensitivity reactions. physiologic concentrations of cortisol suppressed, in vitro, phytohemagglutinin- and concanavalin a-induced proliferation of porcine thymocytes, splenocytes, and peripheral blood mononuclear cells, even though cortisol was only mildly cytolytic. these results extend the con ...19846332317
penetration of trolamine salicylate into the skeletal muscle of the pig.studies to determine the extent of local tissue penetration of topically applied trolamine [14c]salicylate were conducted in domestic pigs. the preparation was applied onto a 100-cm2 shaved area of skin overlying the biceps femoris at a concentration of 0.7 mg of salicylate/cm2 to closely approximate the actual use in humans. at least 82% of the topically applied trolamine salicylate was absorbed over a 2-h period. based on blood and muscle salicylate levels, a localization of the absorbed drug ...19846470939
improvements in the miniature anion exchange centrifugation technique for detecting trypanosomes in domestic pigs. 19846485066
segmental hepatic arterial occlusion with absolute ethanol in domestic swine.four to five ml of absolute ethanol was injected into a segmental hepatic artery in eight pigs to study the occlusive effect on the hepatic arterial system. liver cell damage was indicated by a transient moderate elevation of liver enzymes. follow-up angiography at various time intervals showed persistent occlusion of intrahepatic arteries at different levels in all pigs and occlusion of the common hepatic artery in four. reconstitution of the intrahepatic arterial circulation via abundant intra ...19846485864
the identification of behavioural key features and their incorporation into a housing design for pigs.an ethological approach is presented which aims at meeting the welfare requirements of domestic pigs by satisfying their motivations and behavioural needs. based on the causation of behaviour, welfare may be defined by motivational balance and behavioural needs by environmental and behavioural key features that are essential for the performance of behavioural sequences. ethological minimum requirements were determined from observations of adult and juvenile large-white pigs in semi-natural enclo ...19846486700
[anesthesia protocol in the swine. effects of bleeding on circulation and acid-base equilibrium].haemodynamic parameters and their variations after the loss of 250 and 500 ml of blood under anaesthesia were studied in nine, 11 to 12 week-old, domestic swine weighing 37.4 +/- 2.6 kg. premedication consisted of 2 ml azaperone i.m. anaesthesia was induced with thiopentone, followed by suxamethonium to allow the easy placement of a cuffed endotracheal tube. anaesthesia was maintained with phenoperidine and pancuronium. the animals were mechanically ventilated with a 50/50 nitrous oxide-oxygen m ...19846517396
poor vasoconstrictor response to adrenergic stimulation in the arteriovenous anastomoses present in the carotid vascular bed of young yorkshire pigs.studies using electromagnetic flowmeters and radioactive labeled microspheres (15 +/- 1 micron) have revealed that about 80% of the total common carotid artery blood flow in young domestic pigs (12-14 weeks) is shunted through arteriovenous anastomoses (avas). to investigate the influence of the sympathetic nervous system we measured the distribution of carotid blood flow before and after cervical sympathetic nerve stimulation (2-16 hz), intracarotid infusions of noradrenaline (0.025-0.2 microgr ...19846517648
an electrophoretic characterization of serum proteins of the collared peccary (tayassu tajacu).serum proteins of the collared peccary (tayassu tajacu) were analyzed by agarose gel electrophoresis for wild adult males and females, nursing young, and reproductively-active females in captivity. electrophoretic profiles of the adult peccary showed at least six distinct protein bands corresponding to the fractions: albumin, alpha-1, alpha-2, beta-1, beta-2, and gamma globulin. globulin fractions of the peccary had different mobilities from the domestic swine. the only sexual dimorphisms were a ...19846518761
[cytogenetic studies of crossing of the wild boar (sus scrofa ferus) and the domestic pig (sus scrofa dom.)].in cytogenetic studies on 2 domestic sows (male) crossed with a wild boar (female) karyotype 2n = 37, xx was found. the localization of g brands permitted to confirm that the submetacentric chromosome in the hybrids inherited from the european wild boar corresponds to 2 acrocentric chromosomes of pair 15 and 17 fused by centromeres in the domestic pig. both sows had regular, 18-day sexual cycles. after covering with the wild boar they become pregnant and gave birth to alive progeny. polymorphism ...19846537490
sexual dimorphism involving steroidal pheromones and their binding protein in the submaxillary salivary gland of the göttingen miniature pig.submaxillary glands of mature göttingen miniature pigs were examined for the presence of a sexual dimorphism. gland weights, serous cell hypertrophy and total protein in the glands were much greater in male than female pigs. high concentrations of the pheromonal 16-androstene steroids were present in the glands of males and exceeded 2 mmol/g in some animals; this was primarily due to 5 alpha-androst-16-en-3 alpha-ol. the high concentration of 16-androstene steroids in boar glands was correlated ...19846537966
heterochromatin and nucleolus-organizer-region behaviour at male pachytene of sus scrofa domestica.in the domestic pig (2n = 38) two types of constitutive heterochromatin can be differentiated by fluorescence counterstaining techniques. all 24 biarmed autosomes and the x chromosome have chromomycin a3-positive centromeric c-bands, whereas all 12 acrocentric chromosomes exhibit da-dapi-positive centromeric heterochromatin. fluorescence analysis of male pachytene nuclei revealed that the da-dapi-positive c-bands form one or two large chromocentres per cell, while the chromomycin a3-bright c-mat ...19846543170
[cytogenetic studies of hybridization in wild boars (sus scrofa ferus) and domestic swine (sus scrofa dom.)].in cytogenetic studies on 2 domestic sows (male) crossed with a wild boar (female) karyotype 2n = 37,xx was found. the localization of g brands permitted to confirm that the submetacentric chromosome in in the hybrids inherited from the european wild boar corresponds to 2 acrocentric chromosomes of pair 15 and 17 fused by centromeres in the domestic pig. both sows had regular, 18-day sexual cycles. after covering with the wild boar they become pregnant and gave birth to alive progeny. polymorphi ...19846571467
[localization of ribosomal genes and nucleolar activity in lymphocytes of swine (sus scrofa domestica) stimulated by phytohemagglutinins].the pig chromosomes that contain rdna sites displayed a polymorphism in the distribution of the genes among the nucleolar organizers located on pairs nos. 8 and 10. two, or more often three, active sites were observed in the chromosomes of lymphocytes stimulated with phytohemagglutinin. only 5% of the metaphases showed a 4th small active site. at the onset of stimulation most cells contained one-two nucleoli; four nucleoli were never observed. after prolonged stimulation, the number of nuclei co ...19846428712
evidence for associations of da-dapi fluorescent regions in a subset of peripheral blood lymphocyte nuclei in man (homo sapiens l.) and domestic pig (sus scrofa dom. l.). 19846432637
construction of acid-base alignment nomograms to estimate buffer base and base-excess concentrations in arterial blood from immature pigs.acid-base characteristics of a population of immature domestic pigs were used to construct a blood acid-base alignment nomogram with scales to estimate porcine buffer base concentration. the nomogram was based on average plasma bicarbonate concentration of 31.6 meq/l and plasma albumin and globulin values of 25.4 and 32.2 g/l, respectively. a measurement temperature of 38 c was assumed. subsequently, this nomogram was used to construct a blood acid-base alignment nomogram with scales to estimate ...19846437297
experimental osteo-fluorosis in the domestic pig: a histomorphometric study of vertebral trabecular bone.the experiment aimed at describing effects of fluoride on structure and remodeling of vertebral trabecular bone in pigs. eight animals receiving a supplement of 2 mg f-/kg b.w. per day from age eight to 14 mo were compared with eight controls. plasma fluoride increased from 0.7 +/- 0.1 microm/1 to 12.7 +/- 2.0 microm/1 in pigs receiving fluoride. at slaughter, the concentration of fluoride in dry fat-free bone was 149.3 +/- 10.5 mm/kg for fluorotic animals and 9.5 +/- 0.9 mm/kg for controls. mor ...19846588072
synovial fluid pressure determination in the temporomandibular joint.synovial fluid hydrostatic pressure within the temporomandibular joint of the pig, sus scrofa domesticus, was examined, utilizing the "wick method" for the determination of fluid pressure. acute hydrostatic pressure levels were monitored in seven surgically exposed tmj capsules of five animals. in six out of seven of the surgically exposed tmj capsules, synovial fluid hydrostatic pressure was subatmospheric with the jaw in the resting position (mean = -3.8 mm of mercury). fluid pressure increase ...19846588337
cardiovascular actions after intravenous and intracoronary administration of the slow channel blocker bepridil.the effects of 1-[3-isobutoxy-2-(benzylphenyl)amino]propyl pyrrolidine hydrochloride (bepridil), a new calcium channel blocker, on the systemic and coronary circulation were studied in intact anesthetized domestic pigs. intravenous administration (0.125-0.500 mg x kg-1 x min-1 over 5 min) caused dose-dependent decreases in systemic (8-26%) and coronary vascular resistance (10-41%), but had only a minor effect on cardiac output and myocardial contractility. myocardial o2-consumption decreased sli ...19846608356
[quantitative characteristics of the nucleolus organizer region of the chromosomes in the domestic pig].absolute and relative dimensions of ag+-nors and secondary constrictions (sc) of pig chromosomes were determined. interchromosomal and interindividual variability of these indices were marked. an attempt was undertaken to standardize the absolute sizes of ag+-nors and sc, degrees of chromosome condensation being taken into consideration. a high correlation between the dimensions of ag+-nor and of sc was noted.19846701970
effect of platelet-activating factor on coronary circulation of the domestic pig.the platelet-activating factor released by white blood cells and platelets has been shown to be 1-o-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (agepc). to fully understand the cardiovascular actions of this substance, we examined the effects of agepc on coronary blood flow (cbf) and other hemodynamic parameters in anesthetized open-chest domestic pigs. mean arterial blood pressure (mbp), electrocardiogram, heart rate (hr), left ventricular pressure, and cbf were continuously recorded. agepc ...19846703081
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