Publications

TitleAbstractYear(sorted descending)
Filter
PMID
Filter
free-running rhythms of adrenocorticotropic hormone (acth), cortisol and melatonin in pigs.in the domestic pig, a circadian rhythm of plasma cortisol occurs, with greatest concentrations in the morning and lowest concentrations in the afternoon. however, photic entrainment of the rhythms of acth and melatonin in pigs have not been defined clearly. this experiment was designed to evaluate free-running rhythms of acth, cortisol and melatonin in pigs housed in constant light (ll) and constant darkness (dd). twelve crossbred barrows, maintained under ambient photoperiod, were catheterized ...19911649029
monitoring japanese encephalitis virus activity using domestic sentinel pigs in mandya district, karnataka state (india).domestic pigs were used as sentinels in mandya district (karnataka state) in india during 1984 to 1986 to monitor the activity of japanese encephalitis (je) virus in nature. out of 213 sentinel pigs studied in 11 localities, 44 pigs placed at 5 localities showed seroconversion to japanese encephalitis virus. a pig mosquito cycle, operating throughout the year appears to be one of the maintenance mechanisms of the virus in the study area in addition to the bird-mosquito cycle.19911657767
species-dependent differences of high affinity [3h]paf-binding to platelets from humans and pigs and its inhibition by selected antagonists.the sensitivity of blood platelets towards paf (1-o-alkyl-2-o-acetyl-sn-glycero-3-phosphocholine) strongly varies with species and is primarily responsible for different pathophysiological effects after its administration to experimental animals. platelets from domestic pigs were shown to possess one single class of high-affinity paf-binding sites. receptor density and sensitivity of pig platelets towards paf were distinctly higher than those from humans. preincubation of platelets from both spe ...19911662546
human vntr sequences in porcine htf-islands.mapping of complex genomes has been influenced substantially by the isolation of locus-specific, but repetitive dna elements known as vntrs. since a high gc-content is characteristic of most of these elements one might expect them to be clustered at least partially in cpg-islands. to address this question we have constructed a porcine liver dna noti-linkage library in puc18 using isolated htf-islands. hpaii tiny fragments ranging from less than 100 bp to 1 kb in length were randomly selected and ...19911678358
protective property of azelastine against histamine challenge of rhinal mucosa in domestic pigs.in anaesthetized domestic pigs a filter paper sampling technique was applied to estimate basal and histamine induced nasal secretion. histamine (0.2 mg/nostril) increased secretion more than twofold, a dose of 2 mg/nostril more than 10 fold. intranasally instilled azelastine (a-5610, cas 58581-89-8) prevented this histamine induced rhinorrhea without reduction of basal secretion. the protective effect remained for more than 2 h even when histamine challenge was repeated.19911686828
histochemical demonstration of zinc in the hippocampal region of the domestic pig: ii. subiculum and hippocampus.the distribution of zinc has been described in two areas of the hippocampal region of the domestic pig, viz., the subiculum and the hippocampus. zinc was demonstrated histochemically according to the neo-timm method, a modification of the sulphide-silver procedure. in each of the examined areas the staining displayed a distinctly stratified pattern which has been compared in detail to fields and layers defined on the basis of cyto- and fibroarchitecture, resulting in a combined chemo- and cytoar ...19911709650
distribution of substance p, gnrh, met-enkephalin in the central nervous system of the pig.the distribution of substance p (sp), gonadotropin releasing hormone (gnrh) and met-enkephalin in the brain and spinal cord of the domestic pig is described for the first time. the levels of sp, gnrh and met-enkephalin were measured by specific radioimmunoassays in various regions of the brain and spinal cord of the pig. substance p and met-enkephalin are widely distributed within the central nervous system of the pig. high levels of sp were found in the preoptic area (poa), suprachiasmatic area ...19911714337
[homology between the lpm system of allotypes in the american mink and the gp system of allotypes in the domestic pig].the 5 alpha-macroglobulin allotypes alpha m1, alpha m2, alpha m3, alpha m4 and alpha m5 were identified in pig. the alpha m1 allotype was reported as a marker of pig alpha-macroglobulin, the latter being homologous to alpha 2-macroglobulins in human and in mink. the allotypes alpha m2-alpha m5 were specified as markers of the second isotypical variant of pig alpha-macroglobulins, which was homologous to mink lpm macroglobulin (alpha 1m). as seen from data obtained by international comparative te ...19911714847
localization of calmodulin in epidermis and skin glands: a comparative immunohistological investigation in different vertebrate species.the study deals with the immunolocalization of calmodulin-reactive epithelial cells in different vertebrates (tinca tinca, ambystoma mexicanum, xenopus laevis, rana ridibunda, columba domestica, sus scrofa domestica, homo sapiens sapiens). the immunoperoxidase technique was performed on acetone fixed frozen sections using monoclonal (bf8) and polyclonal (acam) anti-calmodulin antibodies. we were able to differentiate 2 major types of staining patterns: 1. a more superficial epidermal staining in ...19911718122
new data on aberrant spermatozoa in the ejaculate of sus domesticus.this paper describes 16 new types of aberrant spermatozoa observed by scanning electron microscopy in the ejaculate of two healthy, sexually mature landrace boars. the new anomalies observed were 1) spermatozoa with folded tail and abnormal head; 2) tailless spermatozoa with an abnormal connecting piece; 3) immature spermatozoa with two tails of the same length, fused and coiled; 4) spermatozoa with two tails of the same length, fused and coiled, and a small, rounded head; 5) spermatozoa with tw ...199116726941
an experimental technique for heart-lung transplantation in subprimate models.the success of heart-lung transplant experiments in subprimate models has been limited because most techniques include total pulmonary denervation, which causes respiratory problems, blood loss, and subsequent death. using 20 subprimates (12 domestic swine and 8 mongrel dogs), we tested a heterotopic heart-single lung transplant method intended to preserve unilateral pulmonary innervation and to reduce blood loss. after native right pneumonectomy, the donor heart and right lung were transplanted ...199015227176
pronounced accumulation of metoprolol in ischemic myocardium after coronary venous retroinfusion.the myocardial availability of the beta 1-selective blocker metoprolol was compared following standard intravenous (i.v.) administration and after coronary venous retroinfusion. thirteen open-chest farm pigs were subjected to 90-min occlusion of the left anterior descending coronary artery. in six of these pigs, metoprolol was administered as an i.v. injection while 7 pigs received the drug retrogradely into the coronary vein. the time of administration was 5 min. in both groups, metoprolol was ...19901688978
[cytoarchitecture and topography of the ventromedial hypothalamic nuclei of swine (sus scrofa domestica)].the topography and cytoarchitecture of nc. hypothalamicus ventromedialis, nc. hypothalamicus dorsomedialis and nc. infundibularis were descripted in the pig. the nc. hypothalamicus ventromedialis is the dominant nucleus in the tuber cinereum. the rostral pole lies caudal to the nc. hypothalamicus anterior. its caudal pole is bounded by the nc. premamillaris and the nc. hypothalamicus ventrolateralis. scattered neurons separate the nc. hypothalamicus ventromedialis dorsal from the nc. hypothalami ...19901707075
[histotopographic studies of the intramural coronary arteries in the trabecula septomarginalis of the right cardiac ventricle in swine (sus scrofa domesticus) and dwarf goats (capra aegagrus f. domestica)].in the trabecula septomarginalis (moderator band) of pig and pygmy goat regularly till to 6 arteries are found, which traverse from the interventricular septum to the m. papillarius magnus. these intramural coronary arteries (diameter 50-300 microns)--without any exception-musculoelastic intimal thickenings are recognizable, which often marked extensive and formed in the whole vessel length. it is concluded that coronary arteries enlarge in response to increasing intimal thickening and that such ...19902077762
morphology of normal and osteochondrotic porcine articular-epiphyseal cartilage. a study in the domestic pig and minipig of wild hog ancestry.osteochondrosis is a generalized skeletal disorder that affects the growth cartilage in the growing domestic pig but not in the minipig of wild hog ancestry. in the present study, we compare the ultrastructure of the articular and epiphyseal growth cartilage in the domestic pig with that in the minipig. the domestic pigs had areas of enlarged epiphyseal cartilage with chondronecrosis, which had caused focal impairment of the endochondral ossification, with retention of cartilage in the subchondr ...19902077805
recovery after cold cardioplegic arrest of isolated blood-perfused hearts excised from non-anesthetized pigs.an isolated blood-perfused pig heart model has been established in order to evaluate the recovery of hearts obtained from slaughterhouse domestic pigs avoiding anesthesia and direct experiments on animals. eleven hearts subjected to 9 min of normothermic ischemia were infused with cold modified bretschneider solution. after 180 min of cardioplegic-induced global ischemia (including 9 min of normothermic ischemia) 8 hearts were reperfused for 120 min. left ventricular function (measured isovolume ...19902079092
brain oedema and intracranial pressure in superior sagittal sinus balloon occlusion. an experimental study in pigs.about 2/3 of all patients with thrombosis of the superior sagittal sinus (sss) develop signs of increased icp and/or brain oedema (be). the time of onset and the spectrum of symptoms in sss thrombosis vary extremely. this variability might be caused by differences in pathomechanism like be and rise of icp, parameters studied in the present contribution. 10 domestic pigs received a standardized occlusion of the sss with two different balloon types (spherical and cylindrical). they were monitored ...19902089903
[animal experiments for testing the behavior of compacted bone sections using compression osteosynthesis after hyperthermic denaturation].in animal experiments on domestic pigs the behaviour of hyperthermically denatured autogenic compact bone grafts after orthotopic replantation was investigated histologically. it was shown that the inductive osteogenetic celldifferentiation of the lair tissue caused by the autogenetic osteoimplantation depends on the location relationship of the replanted bone grafts to the lair bone tissue. this differentiation had progressed after 14 and 21 days further in the upper indifference area than in t ...19902095646
coronary reactivity in the porcine heart after short lasting myocardial ischaemia: effects of duration of ischaemia and myocardial stunning.the aim was to characterise reactive hyperaemia and endothelium dependent (adp) and independent (adenosine) vasodilatation after ischaemic periods of increasing duration, and in the stunned myocardium.19902097067
intravenous midazolam suppression of pentylenetetrazol-induced epileptogenic activity in a porcine model.generalized tonic-clonic seizures are a neurologic emergency. duration of ictal activity has been associated with neurologic sequelae. the purpose of this study was to determine if midazolam, a short-acting benzodiazepine, could effectively ablate ictal activity in an animal model without significant cardiorespiratory compromise. ten domestic swine (10 to 20 kg) were ventilated and hemodynamically monitored. bifrontal craniotomies were performed and electrocortical activity was recorded througho ...19902105874
increases in coronary vein co2 during cardiac resuscitation.we investigated the aortic, mixed venous, and great cardiac vein acid-base changes in eight domestic pigs during cardiac arrest produced by ventricular fibrillation and during cardiopulmonary resuscitation (cpr). the great cardiac vein pco2 increased from a control value of 52 +/- 2 to 132 +/- 28 (sd) torr during cpr, whereas the arterial pco2 was unchanged (39 +/- 4 vs. 38 +/- 4). the coronary venoarterial pco2 gradient, therefore, increased remarkably from 13 +/- 2 to 94 +/- 29 torr. the simul ...19902112125
[determinants of survival in cardiopulmonary resuscitation].prognostic indices for survival after cardiopulmonary resuscitation (cpr) were investigated in 14 male sprague-dawley rats (500 +/- 50 g) and in 16 domestic pigs (25 +/- 4 kg). arterial and venous blood gas and lactate measurements in association with the coronary perfusion pressure (cpp) and the end-expiratory co2 concentration (etco2) were evaluated. additional parameters in the porcine studies were coronary venous blood gas measurements and intramyocardial ph. volume controlled ventilation wa ...19902112683
opioid control of growth hormone in the suckled sow is primarily mediated through growth hormone releasing factor.endogenous opioid peptides mediate the effect of suckling on lh and prl in the domestic pig. however, the role of opioids in modulating gh during lactation in swine is not known. primiparous sows that had been immunized against grf(1-29) conjugated to human serum albumin (grf-hsa, n = 5) or hsa (n = 4) were used to determine changes in gh after naloxone. treatments were imposed in all sows on day 21 of lactation when antibody titers were 9100 +/- 1629. all sows received (i.v.) naloxone (0.25 mg/ ...19902114957
mono-hydroxyeicosatetraenoic acids during porcine endotoxemia. effect of a platelet-activating factor receptor antagonist.infusion of endotoxin into domestic pigs induces an acute respiratory failure that has many similarities with the adult respiratory distress syndrome. we hypothesized that mono-hydroxyeicosatetraenoic acids (hete) and platelet-activating factor (paf) might be involved in this model of respiratory failure. escherichia coli endotoxin (055-b5) was infused intravenously into anesthetized young pigs at 5 micrograms/kg the first hour, followed by 2 micrograms/kg/hour for 3 hours in the presence and ab ...19902116563
assignment of nucleoside phosphorylase gene to q2.1----q2.2 region of chromosome 7 in the pig, sus scrofa domestica l.using in situ hybridization with a human probe, we have mapped the nucleoside phosphorylase gene on pig chromosome 7. these results are in agreement with those obtained by other groups, but give a more precise localization in the q2.1----q2.2 region of chromosome 7.19902117408
occlusive dressings. does dressing type influence the growth of common bacterial pathogens?we studied the effect of different occlusive dressings and of air exposure on the growth of four pathogenic bacteria in wounds. partial-thickness wounds on domestic pigs were inoculated with staphylococcus aureus, clostridium perfringens, bacteroides fragilis, or pseudomonas aeruginosa. each wound was covered with three dressings (duoderm, opsite, or vigilon), or left exposed to air. groups of wounds were sampled at 24, 48, and 72 hours. staphylococcus aureus reached high levels beneath all of t ...19902119166
in vivo evaluation of simultaneous administration of incompatible drugs via a double-lumen peripheral catheter.for the critically ill patient with complex and prolonged needs, multiple drug infusions and, when indicated, peripheral hyperalimentation require simultaneous administration through a simple peripheral catheter site with a multilumen catheter. we studied a double-lumen peripheral venous catheter. ten domestic swine, 10 to 20 kg, were divided into two groups of five each. total parenteral nutrition was administered through the distal port and phenytoin was administered as a bolus and as an infus ...19902119936
brief report: experimental hepatitis e infection in domestic pigs. 19902122999
the high resolution r-banded karyotype of sus scrofa domestica l. 19902133260
localization of atrial natriuretic peptide/cardiodilatin (anp/cdd)-immunoreactivity in the lacrimal gland of the domestic pig.the presence of atrial natriuretic peptic/cardiodilatin-immunoreactive material was demonstrated in the lacrimal gland of the domestic pig by high performance liquid chromatography and radioimmunoassay. the immunohistochemical localization revealed a distinct population of cuboid or spindle-shaped anp/cdd-ir cells in the epithelium of the terminal portion of the secretory tubules. in addition, a moderate number of positive cells was localized intraepithelially in the intralobular ducts as well a ...19902138565
[immunogenetic characteristics of the gene fund of kakhetian swine and dynamics of population parameters in several generations].some peculiarities of gene fund and dynamics of populational characters of the oldest in europe kakhetian (georgian) pigs were investigated during 18 years (10 generations). genetic peculiarity of the aboriginal species populations in conditions of intensive pressure of natural selection and relatively weak artificial selection was determined with the help of codominant alleles of the blood groups e system. considerable qualitative and quantitative differences were detected between kakhetian pig ...19902146185
simulated left ventricular aneurysm and aneurysm repair in swine.patch reconstruction of left ventricular aneurysm may be superior to linear closure, but this hypothesis has not been tested experimentally. accordingly, six anesthetized domestic pigs were instrumented to measure regional left ventricular wall thickening, stroke volume, systolic left ventricular pressure, and myocardial oxygen consumption. with total bypass and cardioplegia, a 6 by 8 cm dacron patch was inserted into the anteroapical left ventricle. simulations were as follows: left ventricular ...19902146447
restenosis after balloon angioplasty. a practical proliferative model in porcine coronary arteries.a model of proliferative human restenosis was developed in domestic pigs by using deep injury to the coronary arterial media. metal wire coils were delivered percutaneously to the coronary arteries of 11 pigs with an oversized, high-pressure (14 atm) balloon and were left in place for times ranging from 28 to 70 days. during placement, the balloon expanded the coils and delivered them securely within the arterial lumen. light microscopic examination of the vessels confirmed fracture of the inter ...19902146991
detection of aujeszky's disease virus in nasal cells of fattening pigs by immunoassay.both conventional and specific pathogen free pigs were inoculated intranasally with a strain of aujeszky's disease virus (adv). nasal cells were collected daily by swab, aspiration or wash. the nasal cells were examined for adv by isolation on cell culture, direct or indirect immunofluorescence and immunoperoxidase staining by monoclonal antibodies. the infected pigs were studied for nasal shedding of infected cells until 30 days after infection. the study was also extended to naturally infected ...19902154020
fasting energy metabolism of the yucatan miniature pig.the fasting metabolic rates (fmr) of yucatan miniature swine were determined using an open-circuit indirect respiration calorimeter. mature nulliparous females had a mean fmr of 93 kcal/kg bw.75 and did not change significantly during the estrous cycle. this value is comparable to that observed in mature domestic swine. the calculated metabolizable energy requirement for maintenance for the yucatan sow is 116 kcal/kg bw.75. growing yucatan boars had fmr of 127, 119 and 101 kcal/kg bw.75 at 15, 2 ...19902157095
normal physiological values for conscious pigs used in biomedical research.although the domestic pig is rapidly becoming an animal of choice in certain areas of biomedical research requiring a large animal model, effective utilization of the species is often encumbered by a lack of reference values for common functional variables. to address this problem, normal data for over 100 physiologic or related variables were collected from conscious chronically instrumented animals that were maintained under near basal conditions. included were measurements of body composition ...19902162986
serologic survey for transmissible gastroenteritis virus neutralizing antibodies in selected feral and domestic swine sera in the southern united states.serum samples collected from feral and domestic swine (sus scrofa) in florida and feral swine in georgia and texas were assayed by plaque reduction for their virus neutralizing (vn) antibodies against the porcine transmissible gastroenteritis virus (tge). none of 560 samples collected from feral swine contained vn antibodies for tge virus, but experimentally infected feral swine seroconverted. none of 665 samples from domestic swine contained tge-vn antibodies. these results indicate feral swine ...19902167395
neuromuscular transmission in the gastrocnemius muscle of young domestic and wild pigs.the gastrocnemius muscle was stimulated in situ in young female domestic pigs (dp, sus scrofa domestica, german landrace; n = 24) and in european wild pigs (wp, sus scrofa scrofa; n = 20), by short (0.1 ms) square-wave impulses via the sciatic nerve. evoked compound action potentials were recorded from the sciatic nerve, from the ramus muscularis distalis of the tibial nerve and from the end plate region of the muscle tissue. maximum nerve conduction velocities (ncv) were 58.8 +/- 10.4 m/s in dp ...19902168115
c-band fusion and behaviour of the involved chromosomes during meiotic prophase i of the male domestic pig.behaviour of acrocentric chromosome synaptonemal complexes (scs) and constitutive heterochromatin (c-band) during meiotic prophase i of the male domestic pig was studied using surface spreading and silver staining techniques. at late zygotene c-band regions of complete or incomplete scs of the acrocentric chromosomes are represented by enlarged structures. at the same time these structures commenced fusion, which is accomplished at pachytene. using kinetochores and nors as markers, the pachytene ...19902211180
recruitment of mononuclear cells by endothelial cell binding into wounded skin is a selective, time-dependent process with defined molecular interactions.wound healing involves a complex series of interactions between cells in the dermis and epidermis, and important relationships exist between keratinocytes and resident dermal cells. monocytes and lymphocytes secrete cytokines that are capable of stimulating dermal repair and influencing keratinocyte and fibroblast migration and proliferation, although the mechanism by which mononuclear cells are recruited into the wound is unknown. we have tested the hypothesis that in wounded skin specialized e ...19902212726
maintenance and differentiation in culture of pluripotential embryonic cell lines from pig blastocysts.cell lines were established from explanted blastocysts of domestic pigs; the cells could be maintained indefinitely when grown on mouse fibroblast feeder cell layers. they differentiate spontaneously at high densities, or when allowed to form aggregates when cultured on a non-adhesive substratum. their appearance and differentiative behaviour resembles that of mouse embryonic stem cell lines. we are currently attempting to establish whether these cultures represent primary ectodermal lineages wh ...19902213715
responses of harbor seal and pig heart to progressive and acute hypoxia.myocardial oxidative and glycolytic reserves were evaluated in four harbor seals, phoca vitulina richardsi, and six domestic pigs, sus scrofa (hematocrits: 58 +/- 5 and 34 +/- 1%., respectively). progressive hypoxia was induced by lowering arterial hemoglobin-oxygen saturation in 10% decrements, each maintained for 10-min periods, until the onset of heart failure. myocardial oxygen consumption rate (vo2), lactate release/uptake rate (l), and triple product, an index of myocardial energetic deman ...19902221153
nisoldipine inhibits lipid peroxidation induced by coronary occlusion in pig myocardium.the aim was to investigate the effect of the ca++ channel blocker nisoldipine on the content of lipid peroxidation products in pig myocardium after acute coronary occlusion.19902224937
protective effect of verapamil in ischemic porcine hearts: analysis of ultrastructural and metabolic changes using in vivo 31p-nmr spectroscopy.to assess the protective effect of verapamil on ischemic myocardium, the changes in high energy phosphates, inorganic phosphate, and intracellular ph were serially and quantitatively measured in ischemic porcine hearts without collateral circulation using 31p-nmr spectroscopy, together with ultrastructural examination. twenty-six farm pigs weighing 11 to 14 kg were anesthetized with fluothane and were divided into control (c) group and verapamil pretreatment (v) group. in v group 0.2 mg/kg of ve ...19902231744
importance of acid-base strategy in reducing myocardial and whole body oxygen consumption during perfusion hypothermia.during induced hypothermia with cardiopulmonary bypass, acid-base management usually follows one of two strategies: the so-called ectothermic or alpha-stat strategy, in which the ph of the arterial blood increases 0.015 ph units for every degree celsius decrease in body temperature, or the ph-stat strategy, in which ph remains 7.4 at all temperatures. it has been assumed that oxygen consumption decreases approximately equally during hypothermia with either strategy, although there are biochemica ...19902232832
quantum type bone remodeling in the otic capsule of the pig.normal quantum type bone remodeling was studied in temporal bones of young domestic pigs by means of combined microradiography, osteofluorochrome labelling and osteoid staining. evolving secondary osteons were morphologically normal although much less in the otic capsule than in the surrounding compacta of the temporal bones or in long bones. moreover, remodeling was totally absent in bone tissue immediately adjacent to perilymphatic spaces suggesting the presence of a local mechanism controllin ...19902239210
postnatal development of the hair cycle in the domestic pig.the postnatal patterns of hair follicle activity have been quantified in pigs born in summer and winter. animals were skin sampled monthly during the first year of life and the stages of the hair cycle were identified from follicles in histological sections. percentages of active follicles were used to determine hair cycle patterns and as a measure of how the hair cycle became synchronised with that of the adult. at birth, in excess of 95% of follicles were active in fibre production. within the ...19902254156
meiotic chromosome behaviour reflects levels of sequence divergence in sus scrofa domestica satellite dna.we present a general model for the evolution of chromosome-specific satellite dna subfamilies. sus scrofa domestica has a bimodal karyotype with two autosomal subsets of 12 meta-/submetacentric (mc) and 6 acrocentric (ac) chromosome types (mc and ac "subgenomes"). we show that the centromeric heterochromatin is characterised by two distinct satellite dna families designed mc1 and ac2. mc1 is a diverse satellite family of the mc subgenome of which certain members with a 100 bp repeat unit are fou ...19902265570
[expression of constitutive heterochromatin by alui restriction endonuclease treatment and ca3/da/dapi staining of domestic pig chromosome].the heterogeneity of constitutive heterochromatin in two domestic pigs has been studied by restriction endonuclease alui banding, ca3/da/dapi banding and c-banding techniques. the results show that the centromere constitutive heterochromatin can be subdivided into three types, which located in different chromosomes. it is found that there is correspondence between no. 13--18 chromosomes in pigs and no. 1, 9, 16, y chromosome in human by comparing the banding patterns of alui and ca3/da/dapi. the ...19902268447
hearing in domestic pigs (sus scrofa) and goats (capra hircus).behavioral audiograms were determined for three pigs and two goats. the hearing of the pigs ranged from 42 hz to 40.5 khz with a region of best sensitivity from 250 hz to 16 khz. hearing in goats ranged from 78 hz to 37 khz with a well-defined point of best sensitivity at 2 khz. because these animals are unable to localize high-frequency tones, it seems unlikely that selective pressure to use the interaural spectral-difference cue for sound localization is behind their high-frequency hearing. in ...19902272932
plasma concentrations of laudanosine, but not of atracurium, are increased during the anhepatic phase of orthotopic liver transplantation in pigs.to quantify the changes in plasma concentrations of atracurium and laudanosine induced by the lack of hepatic function and circulation, the authors studied nine domestic pigs (22-25 kg) undergoing an orthotopic liver transplantation, and three control animals without surgery, using atracurium as the muscle relaxant. after intubation facilitated by isoflurane 2-3%, anesthesia was maintained with isoflurane (0.5% in oxygen) and fentanyl (4 micrograms.kg-1.hr-1). ventilation was controlled to keep ...19902297117
postnatal developmental profile of 3-hydroxy-3-methylglutaryl-coa reductase, squalene synthetase and cholesterol 7 alpha-hydroxylase activities in the liver of domestic swine.activities of 3-hydroxy-3-methylglutaryl-coa reductase, squalene synthetase and cholesterol 7 alpha-hydroxylase, measured in liver microsomal preparations from domestic swine between birth and adolescence, correlated strongly in individual animals. a synchronous increase was observed between 4 and 6 weeks after birth, i.e., immediately after weaning. rise in activity was highest for hmg-coa reductase (30-fold), and smallest for squalene synthetase (5-fold). in pubertal pigs (16 to 30 weeks old), ...19902297519
atherosclerotic yucatan microswine: an animal model with high-grade, fibrocalcific, nonfatty lesions suitable for testing catheter-based interventions.a new breed of swine, the yucatan microswine, that was derived from repetitive inbreeding of selected, small yucatan swine, was investigated as an animal model of advanced vascular atherosclerosis. nineteen animals were fed an atherogenic diet for 9.9 +/- 1.5 (mean +/- sem) weeks before and 19.9 +/- 1.8 weeks after balloon endothelial denudation of all four iliac arteries. in 18 (94.7%) of the 19 microswine, angiography performed at 33 to 87 weeks of age disclosed some degree of luminal diameter ...19902301218
effects of physostigmine on the cardiopulmonary system of conscious pigs.physostigmine, as a pretreatment candidate for nerve agent poisoning, was examined for cardiopulmonary side effects. cardiovascular and pulmonary parameters were monitored in unanesthetized domestic pigs which received pulmonary arterial infusion of 5 micrograms/kg/min physostigmine salicylate for 2 hr. a level of 74% inhibition of red blood cell (rbc) acetylcholinesterase (ache) activity was attained in 45 min, and this level of carbamylation increased only slightly during the remaining infusio ...19902307326
second-degree burn healing: the effect of occlusive dressings and a cream.because occlusive dressings and some creams have been found to speed epithelialization of blade-induced wounds, we studied the effect of two occlusive dressings and a polyglycerylmethacrylate cream containing low concentration of fibronectin on epithelialization in second-degree burn wounds. cylindrical brass rods were heated in a boiling water bath, removed, wiped dry, and placed (6 sec) on the skin of domestic pigs. the burned epidermis was removed and each burn wound was assigned to one of th ...19902314098
cocaine hepatotoxicity in cultured liver slices: a species comparison.studies were carried out in order to find a sensitive in vitro model with which to investigate cocaine-mediated hepatotoxicity. precision-cut liver slices were prepared from: human, domestic pig, new zealand white rabbit, sprague-dawley (s/d) rat, and two mouse strains (dba/2ha and icr). the rationale for the choice of these species was that information on in vivo effects of cocaine was available in the literature. slices were cultured for up to 6 h in the presence of 0-5 mm cocaine. indices of ...19902321245
masseter muscle performance. significance of structure and metabolism. a morphological and experimental study.the aim of this thesis was to characterize structural factors in masticatory systems relevant to functional evaluations and to elucidate the effect on energy metabolism of electrically induced jaw muscle fatigue. an omnivorous masticatory system (the domestic pig) was compared morphologically with a carnivorous (the dog). porcine masseter muscles were evaluated by atp-ase histochemistry as well as with nadh-dehydrogenase and pas-staining. contractional characteristics were obtained from the porc ...19902326743
analysis of naturally occurring deletion variants of african swine fever virus: multigene family 110 is not essential for infectivity or virulence in pigs.a comparison of uncloned african swine fever virus isolates with their cloned counterparts revealed the presence of genetic variants in three out of seven uncloned field virus populations tested. five different virus clones were isolated from the uncloned kir69 virus stock by limit dilution. structural analysis of the variants showed that they differed by single deletions of 10-16 kilobases in the region located between 6.8 and 27 kilobases from the left dna terminus. there was no homology betwe ...19902330671
[crown wall thickness, external dimensions and solid pulp substance relationships of swine teeth].investigations had been carried out with 60 premolars of the upper and lower jaws in 2-year old domestic pigs in relation to their crown dimensions, their layer thickness of enamel and dentine.19902334060
the purification and characterization of a fatty acid binding protein specific to pig (sus domesticus) adipose tissue.western-blot analysis using antiserum to 3t3-l1-cell fatty acid binding protein (fabp) revealed that pig adipose tissue contains a 15 kda protein immunologically similar to the murine protein. this 15 kda protein was purified from pig adipose tissue by sequential application of sephadex g-50 gel filtration, cation exchange and covalent chromatography on thiol-sepharose-4b. the purity of the pig protein was established by two-dimensional polyacrylamide-gel electrophoresis. isoelectric focusing in ...19902334399
[light and electron microscopic studies of the histopathogenicity of macracanthorhynchus hirudinaceus (archiacanthocephala) in experimentally infected domestic swine].one and 12 weeks after infection the lesions in the small intestine of two domestic pigs caused by macracanthorhynchus hirudinaceus were studied by means of light and electron microscopy. worms of 7 d.p.i. were found to have penetrated with their presoma into the tunica propria and partly into the tunica muscularis where they had caused local mechanic destructions and heavy eosinophilic-like and hemorrhagic reactions. most eosinophilic-like granulocytes were attracted to the proboscis hooks, at ...19902336449
rapid ventricular pacing in pigs: an experimental model of congestive heart failure.to develop an improved animal model of congestive heart failure, 11 female farm pigs (wt, 42-46 kg) underwent rapid ventricular pacing at 230 beats/min for 7 days with a modified medtronic unipolar pacemaker connected to an apical pacing lead. after 7 days the pacemaker was turned off, anesthesia induced, the chest opened, and cardiac hemodynamic and dimensional studies were performed. results were subsequently compared with data from 12 control pigs that received no pacing. two pigs died before ...19902337189
electrocardiographic effects of experimental myocardial infarction in pigs.myocardial infarctions were produced in young domestic farm pigs by ligating coronary arteries. arteries ligated in four groups were (a) left anterior descending, (b) branches of left anterior descending, (c) left circumflex, and (d) right coronary artery. after 7 or 8 days, the hearts were removed and dissected and the infarcted areas measured. vectorcardiograms were taken before ligation and just before termination. high recording speeds and sensitivities were used so that details of the qrs c ...19902341815
neuronal and adrenal enkephalins and catecholamines in response to acute cns ischemia and reserpine in pig.co-storage of enkephalins and catecholamines in coronary artery, mesenteric artery and vein, middle cerebral artery, vas deferens and adrenal medulla was studied in domestic pig (sus scrofa). responses to acute cns ischemia were correlated with time to peak plasma levels of central venous and adrenal vein outflow samples in controls, during reserpine treatment and after drug withdrawal. endogenous enkephalins are co-stored in chromaffin granules of adrenal epinephrine-type cells and large dense ...19902348053
[the effect of large-faced cerebral meningeal fibroses on the development of hemispheric volume. experimental and morphometric studies of swine brains].alterations that occurred to the hemispheric structure as a result of experimentally induced meningeal fibrosis are reported in this paper. the rinsing function of cerebrospinal fluid was unilaterally stopped in the subarachnoidal space of domestic pigs by means of a viscous medium which contained soluble fatty acid salts. the animals were sacrificed 35 or 95 d after the experiments. series of frontal sections of both cerebral hemispheres were planimetrically measured to establish differences be ...19902356672
the physiology of adaptation to small bowel resection in the pig: an integrated study of morphological and functional changes.this study examined the adaptive response to extensive small intestinal resection in the juvenile domestic pig. control animals underwent an ileal transection with end-to-end anastomosis, whereas resected pigs had a resection of the mid-75% of the total small bowel length. animals were followed for 16 weeks. resected animals gained less weight than controls, with no significant difference in feed intake per unit animal weight. in vivo fat, protein, carbohydrate, and total energy absorption were ...19902359003
measurement of mean circulatory filling pressure and vascular compliance in domestic pigs.to measure mean circulatory filling pressure (pmcf), a balloon was placed in the right atrium of seven pentobarbital sodium-anesthetized open-chest pigs for transient occlusion of flow combined with mechanical transfer of blood from the arterial to the venous circulation. equilibration occurred within 6-8 s at a pressure at 12.3 +/- 0.3 (se) mmhg after a 2.9 +/- 0.2 ml/kg transfer of blood. in another group of pentobarbital sodium-anesthetized closed-chest pigs, acetylcholine (ach) was used to i ...19902360680
[mortality by crushing in domestic pigs: study of the causes and their relationship to the time and the month of the year in the climatic conditions of cuba].in the course of 3 years a complex of 25,000 pigs were investigated once per week for the dead among the 398 sucking piglets, and in the case of losses due to crushing to death the type of lesions and the connection with diseases was investigated. of the piglets investigated, 88 were crushed to death (21.2%), among them 65 (73.8%) diseased--mainly infected by coli bacilli (60 = 68.2%)--and 23 (5.8%) healthy animals. the losses due to crushing to death were highest in january and differed from al ...19902360897
temporomandibular synovial fluid pressure response to altered mandibular positions.hydrostatic synovial fluid pressure within the superior aspect of the temporomandibular joint space of the growing pig, sus scrofa domesticus, was examined in response to various acute and chronic alterations of mandibular position. bilateral measurements of pressure were recorded with chronically implanted wick catheters in three 8-week-old pigs before and at the time of appliance placement and then at 2-day intervals until the animals were 20 weeks old. besides confirming the observations of a ...19902363402
cholinergic regulation of resting coronary blood flow in domestic swine.cholinergic vasoconstriction in vivo and the influence of resting cholinergic activity on basal coronary tone were investigated by measuring coronary blood flow, cardiac function, and blood gases during either acetylcholine injection, muscarinic receptor blockade, or vagal ligation, in open-chest chloralose-urethan-anesthetized swine. intracoronary injections of acetylcholine (0.5-3.0 micrograms) caused significant (p less than 0.05) dose-dependent reductions in coronary blood flow (19.0-75.5%) ...19902375397
volumetric comparison of auditory structures in the brains of european wild boars (sus scrofa) and domestic pigs (sus scrofa f. dom.).the size of certain brain parts involved in the processing of auditory stimuli was measured in european wild boars (sus scrofa) and domestic pigs (sus scrofa f. dom.). by means of intraspecific allometric methods for analyzing the brain weight to body weight relationships, the volumes were compared in both groups. in general, all measured structures were smaller in the domestic form, indicating that domestication has led to a decrease in the size of auditory brain parts. within the auditory syst ...19902375973
immunocytochemical demonstration of the calcium-binding proteins calbindin-d 28k and parvalbumin in the subiculum, hippocampus and dentate area of the domestic pig.the distribution of the calcium-binding proteins calbindin-d 28k (cabp) and parvalbumin (pv) in the hippocampal region of the domestic pig was demonstrated by immunocytochemistry. scattered cabp-immunoreactive cell bodies were present in the subiculum, stratum oriens, pyramidal cell layer and stratum radiatum of the hippocampal regio superior and inferior, and the outer plexiform layer and outer hilar cell layer of the dentate hilus. other cell bodies and bundles of stained fibers were present i ...19902392572
the role of alpha 1-adrenoceptors in adrenaline-induced hyperkalaemia.the hyperkalaemic action of adrenaline was investigated in 44 anaesthetized domestic pigs. plasma and epicardial concentrations of k+ were measured, in the latter case with an ion-selective electrode. adrenaline 10 micrograms kg-1 caused a rapid increase in the plasma concentration of k+ from 4.2 to 5.9 mmol litre-1. the magnitude and the time course of epicardial concentration of k+ were similar. alpha-adrenoceptor block with either phentolamine 5 mg kg-1 (non-selective block) or prazosin 0.1 m ...19901979911
protective effects of nipradilol, isosorbide dinitrate, and bunazosin on coronary artery constriction induced by intracoronary injection of acetylcholine in pigs.protective effects of nipradilol, a newly synthesised vasodilating beta adrenoceptor antagonist, isosorbide dinitrate, and bunazosin on coronary artery constriction induced by intracoronary injection of acetylcholine were determined by coronary arteriography and compared in vivo in pigs.19901982930
epinephrine-induced premature ventricular contractions and changes in arterial blood pressure and heart rate during i-653, isoflurane, and halothane anesthesia in swine.i653 is a new inhalation anesthetic having especially desirable recovery characteristics because of its very low blood and tissue solubility. investigations of its cardiovascular and electroencephalographic effects have revealed actions similar to those of isoflurane. however, these studies did not evaluate the potential of i653 to predispose the heart to epinephrine-induced arrhythmias. in this investigation, we studied eight domestic swine to compare the effects of i653 with those of other ane ...19892464293
histochemical demonstration of zinc in the hippocampal region of the domestic pig: i. entorhinal area, parasubiculum, and presubiculum.a detailed description is given of the distribution of zinc in three areas of the domestic pig hippocampal region, viz., the entorhinal area, the parasubiculum, and the presubiculum. zinc was demonstrated histochemically with use of the neo-timm method, a recent modification of the sulphide silver procedure. each of the studied areas showed a distinctly stratified staining pattern, which has been correlated in detail to fields and layers defined on the basis of cyto- and fibroarchitecture, provi ...19892477401
prenatal development of the adrenal gland in the pig (sus scrofa domestica). part i. the differentiation and development of the adrenal cortex primordium in the first half of pregnancy.the differentiation and development of the adrenal gland in pig embryos from 18 to 48 days of pregnancy were investigated with histological and histochemical methods and in electron microscope. primordia of the adrenal cortex appear at 21st day as two symmetrical streaks of the condensed mesenchymal cells between the mesonephros, aorta dorsalis and mesenterium. the capillaries and chromaffinoblasts penetrate the primordium. the mesenchymal cells differentiate into adrenal cortical cells. in the ...19892485767
prenatal development of the adrenal in pig sus scrofa dom. part ii. adrenal cortex development in the second part of pregnancy.the development of the adrenal cortex in pig fetuses between the 50 and 112 day of pregnancy were investigated with histological and histochemical methods and in electron microscope. three consecutive generations of the cortical cells were observed. they had features of steroidogenic cells and differed with mature of mitochondria and in amount of ser and in enzyme activity. the earliest differentiated fetal cortical cells demonstrated alkaline phosphatase activity and giant mitochondria. they we ...19892485783
ultrastructural and histochemical investigations of the development of the medullary part of the adrenal gland in domestic pig (sus scrofa dom.) during the prenatal period.the development of the adrenal medulla was investigated during the prenatal period in the pig. the observations were carried out on 221 embryos from 21 to 112 day post coitum. the histological, histochemical, ultrastructural and stereological methods were performed. first chromaffinoblasts infiltrated the adrenal cortex primordium around the 27-th day pc. they were mixed with cortical cells and just in the last days of pregnancy they were localized only in central part of adrenal. the chromaffin ...19892485784
the ultrastructure of capillary walls and perivascular space of the pineal gland in three representatives of suidae species.the ultrastructure of capillary vessels and the perivascular space (pvs) of the pineal gland were investigated in the domestic pig, miniature pig, and wild boar. it has been ascertained that the capillaries of these animals have continuous thick walls without pores and fenestrations. in fetal period, capillaries with spacious lumina, bordered by 3 to 4 endothelial cells predominate. the pvs, as a rule wide open, contain nerve endings, pinealocyte process endings, and collagenous fibers which inc ...19892485786
spectral sensitivity of cones in an ungulate.ungulates have been classified as having arrhythmic eyes in the sense that they contain features appropriate both to diurnal and nocturnal life. the former is typically associated with multiple classes of cones and a color-vision capacity. to see if an arrhythmic animal has these features, the number of cone classes was determined and the spectra of these cones were measured in a common ungulate, the domestic pig (sus scrofa). examination with electroretinogram (erg) flicker photometry revealed ...19892487648
myocardial acidosis associated with co2 production during cardiac arrest and resuscitation.previous studies from our institution demonstrated significant hypercarbic acidosis in the mixed venous (pulmonary artery) blood in animals and human patients during cardiac arrest and cardiopulmonary resuscitation (cpr). in the present study, the acid-base state of the myocardium during cardiac arrest was investigated. cardiac arrest was electrically induced in 11 pentobarbital-anesthetized and mechanically ventilated domestic pigs. precordial compression was begun 3 minutes after onset of vent ...19892504512
myocardial potassium uptake during experimental cardiopulmonary resuscitation.changes in myocardial k+ handling were examined during ventricular fibrillation and subsequent cpr in ten domestic swine. during ventricular fibrillation, there was initial k+ efflux from the myocardium which was followed by myocardial k+ uptake during precordial compression. after successful defibrillation, a washout in k+ was observed. coronary potassium clearance was inversely related to the myocardial [h+], pco2, and lactate production. a negative correlation between cardiac vein [k+] and my ...19892504539
the effect of gas permeability of film dressings on wound environment and healing.we have determined the effect of oxygen and carbon dioxide permeability of thin film dressings on wound exudate p o2, p co2, ph, and epithelialization in shallow wounds on domestic pigs. three kinds of films were compared: polyvinylidine chloride, a low gas permeability film; polyurethane, a medium gas permeability film; and poly(dimethyl silicone), a high gas permeability film. exudate under the silicone film had the highest p o2 and the lowest p co2; exudate under the polyurethane had intermed ...19892506289
effect of zearalenone on early pregnancy in guinea pigs.female guinea pigs were tested to determine whether they could serve as a model of zearalenone (zen) toxicosis during early pregnancy, as observed in domestic swine. only 1 of 4 female guinea pigs that were given 21 mg of zen/kg of body weight orally during the first 8 days after mating was pregnant when examined 22 days after mating. guinea pigs that were given 7 or 14 mg of zen/kg had normal fetal development. serum concentrations of progesterone were less than 12 ng/ml in all guinea pigs 8 an ...19892528930
a survey of wild swine in the united states for evidence of hog cholera.the results of surveillance for hog cholera (hc) in wild swine (sus scrofa) collected from throughout the united states from 1979 to 1987 are presented. sera collected from 1,218 wild swine and tissues from 637 were evaluated for hc antibodies and virus, respectively. included within this surveillance were samples from santa cruz and santa rosa islands, california, where hc virus had been deliberately introduced into wild swine during the 1950's in attempts to eradicate these animals. all evalua ...19892536850
[estimation of the incidence of human trypanosomiasis due to trypanosoma brucei gambiense using epidemiological parameters essentially linked to the vector: case of a focus in the ivory coast].the entomo-epidemiological studies carried out from 1980 to 1985 in the human trypanosomiasis focus at bouaflé (ivory coast) were designed to estimate the main epidemiological parameters related to g. palpalis palpalis, the sleeping sickness vector in the zone considered. this paper defines the mathematical relationships which can exist between these parameters leading to the production of a simple model enabling estimates to be made of the incidence of human trypanosomiasis caused by t.b. gambi ...19892552942
plasma catecholamines, ph, and blood pressure during cardiac arrest in pigs.this study examined plasma epinephrine (e) and norepinephrine (ne) concentrations, ph, and mean arterial blood pressure (map) in a cardiac arrest model. twenty-three domestic swine (15-26 kg) were anesthetized with ketamine 20 mg/kg, i.m. and alpha-chloralose 25 mg/kg, i.v. and ventilated with a respirator. catheters were placed in the right ventricle, left ventricle and femoral arteries for map recordings and blood ph sampling every 2 min. catecholamine samples were taken from the femoral arter ...19892554447
[effect of cysteinyl leukotrienes on uterine strips from pregnant and non-pregnant swine].cysteinyl leukotrienes c4, d4 and e4 elicited concentration-dependent contractile response of pregnant and non-pregnant pig uterine strips during incubation in de jalon solution in concentrations between 1 x 10(-9)m and 1 x 10(-5)m for ltc4 and ltd4, and between 1 x 10(-8)m and 1 x 10(-5)m for lte4. the maximum contractions elicited by leukotrienes were 77.5 +/- 3.0%, 86.0 +/- 2.6% and 37.5 +/- 2.5% of these elicited by histamine 1 x 10(-5)m for ltc4, ltd4 and lte4, respectively. fpl 55712, leuk ...19892562080
porcine adrenal prolactin receptors: characterization, changes during neonatal development and effects of hypoprolactinemia.1. adrenal prolactin (prl) receptors were identified within the adrenal cortex of pigs (sus domesticus), and found to be located specifically on isolated zona fasciculata/reticularis cells (6437 sites per cell). 2. these prl receptors were associated with binding to [125i]-oprl which was characterized as being time and temperature dependent, specific for prl, saturable, of high affinity (ka = 10(10)/m) with a single class of binding sites, and irreversible except under extreme conditions. 3. the ...19892566410
influence of various adrenergic compounds on plasma potassium levels in conscious dogs and anaesthetized domestic pigs.the influence of various compounds with affinity to beta-adrenoceptors on plasma potassium levels was investigated in conscious dogs and anaesthetized pigs. there was a marked fall, amounting to about 1 mmol/l following salbutamol and pirbuterol but nearly no effect following dobutamine and xamoterol. in dogs the hypokalaemic effect of salbutamol was augmented when prazosin was additionally applied. it is concluded, that the plasma potassium level is reduced mainly by beta 2-adrenoceptor stimula ...19892576204
a highly repeated sequence in the domestic pig: a gender-neutral probe. 19892602124
histopathological features of unilateral stapling in animal experiments.blount stapling of the proximal medial tibial growth was performed in 10-week-old domestic pigs. a total of 37 animals for up to 17 weeks were followed up. the histological evaluation showed a different reaction of the growth plate in the medial (stapled), central and lateral area. up to 6 days after stapling the morphological features were characterized by deviations of the cell column from the axial alignment. herniations of mature chondrocytes as well as isles of epiphyseal cartilage splinter ...19892619521
effects of fluoride on cortical bone remodeling in the growing domestic pig.the purpose of the experiment was to assess the effects of fluoride (f-) on the remodeling process of cortical bone. sixteen pigs, eight experimental animals receiving a supplement of 2 mg f-/kg b.w. and eight controls, were studied in individual sites from age 8 to 14 months. at slaughter samples of cortical bone were obtained from the right femur and embedded undecalcified. a new stereologic model based on fluorochrome tissue time markers and isotropic uniform random histologic sections was im ...19892624822
evidence from immunoblotting studies on uncoupling protein that brown adipose tissue is not present in the domestic pig.adipose tissues and other tissues of the pig have been examined for the presence of the mitochondrial "uncoupling protein," characteristic of brown adipose tissue, in order to assess whether brown fat is present in this species. mitochondria were prepared from various tissues and the proteins separated on the basis of molecular weight by sodium dodecyl sulphate--polyacrylamide gel electrophoresis. immunoblotting procedures were then used to probe for uncoupling protein, employing a rabbit anti-( ...19892627687
[trichinelliasis in western podolia].situation with trichinosis in the ternopol province (ukraine) in the period from 1962 to 1987 was studied. muscle samples taken from 6695 animals of 20 species were investigated by the compressor method and by the method of digestion in artificial gastric juice. trichinosis was detected in wolves, foxes, martens, ferrets, domestic dogs, cats and gray rats. in 1954--1979 39 trichinosis cases were registered in humans with 4 lethal cases. domestic pigs proved to be the source of invasion. since 19 ...19892628712
[morphometric study of bone in domestic pigs with fluorosis caused by coal-burning pollution].forty four domestic pigs were divided into 2 groups: control group: 17 pigs; fluorosis group: 27. they were fed for 14 months in the endemic area or non-endemic area respectively. in some of the pigs, double tetracycline was given for bone dynamic study, and blood and urine were collected for biochemical analyses. iliac, tibia, fibula, the 2nd metatarsal and the 2nd vertebrae were reserved either for bone density measurement or for bone histomorphometric study. the results showed that fluoride c ...19892630015
fetal pancreas transplantation in miniature swine. ii. survival of fetal pig pancreas allografts cultured at room temperature.islet-allograft survival has been shown to be markedly prolonged in rodents when donor tissue has been precultured at 24 degrees c. in this study, the feasibility of this approach was tested in nih minipigs transplanted with fetal pancreases. collagenase-digested fetal pig pancreatic tissues survived in culture at 24 degrees c for 6-7 days and continued to grow in vitro at 37 degrees c after being transferred. these tissues no longer stimulated allogeneic lymphocytes in vitro, although some tiss ...19892642849
prevalence of streptococcus suis types 1 and 2 in domestic pigs in australia and new zealand.using an indirect fluorescent antibody test, 54 per cent of 734 palatine tonsils of conventional pigs slaughtered in australia and new zealand were found to be infected with streptococcus suis type 1 and 73 per cent of 959 were infected with s suis type 2. variations in the prevalence of infection in pigs from different herds were thought to be due to differences in the sample sizes rather than to real differences in the prevalence between herds. the prevalence of infection with s suis was simil ...19892658296
ciclopirox olamine lotion 1%: bioequivalence to ciclopirox olamine cream 1% and clinical efficacy in tinea pedis.studies were conducted to assess the bioequivalence of a new antimycotic formulation, ciclopirox olamine lotion 1%, to an established compound, ciclopirox olamine cream 1%. results of in vitro studies, using skin samples from human cadavers and domestic pigs, demonstrated that the two formulations equally penetrate all layers of the stratum corneum and inhibit the growth of trichophyton mentagrophytes and candida albicans. in vivo studies in guinea pigs and in human volunteers demonstrated the c ...19892663159
Refresh
firstprev
...31323334353637383940...
nextlast
Displaying items 3901 - 4000 of 4678