Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| validating the factor structure and testing measurement invariance of modified short-form mcgill pain questionnaire (ortho-sf-mpq) for orthodontic pain assessment. | to validate the factor structure of recently modified short-form mcgill pain questionnaire (ortho-sf-mpq) to assess orthodontic pain; and to test its measurement invariance (mi) across gender. | 2017 | 28168942 |
| psychometric evaluation of the youth eating disorder examination questionnaire in children with overweight or obesity. | this study evaluated the psychometric properties of the youth eating disorder examination questionnaire (yede-q) and its utility for detecting loss of control (loc) eating (i.e., eating episodes, regardless of size, involving a perceived inability to control what or how much one is eating) among school-age children with overweight or obesity. identifying eating pathology, particularly loc eating, in this population may facilitate treatment that improves weight outcomes and reduces eating disorde ... | 2017 | 28205275 |
| validation of the psychometric properties of cognitive fusion questionnaire. a study of the factorial validity and factorial invariance of the measure among osteoarticular disease, diabetes mellitus, obesity, depressive disorder, and general populations. | the cognitive fusion questionnaire (cfq) is a self-report questionnaire that assesses the extent to which individuals are psychologically entangled with, and dominated by the form-content of their thoughts. the aim of this study was to replicate the factor structure of cfq in osteoarticular disease, diabetes mellitus, obesity, depressive disorder, and normative population. it further examined the factorial invariance of the cfq across these 5 groups. | 2017 | 28198068 |
| validated hplc method for the pharmacokinetic study of oral extended-release cefpodoxime proxetil chitosan-alginate beads in rabbits. | the aim of this study is to develop a simple and applicable hplc method for the detection of cefpodoxime acid (cfa) in rabbit plasma after oral administration of cefpodoxime proxetil (cfp) loaded chitosan-alginate (ch-alg) beads formulation. cfp is a prodrug that is deesterified in vivo to its active metabolite cfa to exhibit antibiotic activity. chromatographic separation of cfa and internal standard (is) was achieved by a rp18(c18), phenomenax®100, (250×4.6mm) with the mobile phase consisting ... | 2017 | 28137463 |
| cerebrolysin reduces mechanical allodynia in a rodent model of peripheral inflammation. | cerebrolysin (cbl) is a neuropeptide preparation of cerebroproteins that crosses the blood brain barrier displaying neuroprotective properties and promoting neurogenesis. limited evidence exists on the efficacy of cbl for the treatment of pain, with many studies focusing on neuropathic pain associated to diabetes. therefore, we designed a study to test the hypothesis that cbl would reduce mechanical allodynia in a rat model of peripheral inflammation induced by administration of complete freund' ... | 2017 | 28131658 |
| psychosocial factors in the relationship between socioeconomic status and cardiometabolic risk: the hchs/sol sociocultural ancillary study. | u.s. hispanics/latinos display a high prevalence of metabolic syndrome (metsyn), a group of co-occurring cardiometabolic risk factors (abdominal obesity, impaired fasting glucose, dyslipidemia, elevated blood pressure) associated with higher cardiovascular disease and mortality risk. low socioeconomic status (ses) is associated with higher risk for metsyn in hispanics/latinos, and psychosocial factors may play a role in this relationship. | 2017 | 28130624 |
| a more rational, theory-driven approach to analysing the factor structure of the edinburgh postnatal depression scale. | we endeavoured to analyze the factor structure of the edinburgh postnatal depression scale (epds) during a screening programme in hungary, using exploratory (efa) and confirmatory factor analysis (cfa), testing both previously published models and newly developed theory-driven ones, after a critical analysis of the literature. between april 2011 and january 2015, a sample of 2967 pregnant women (between 12th and 30th weeks of gestation) and 714 women 6 weeks after delivery completed the hungaria ... | 2017 | 28167438 |
| lentiviral vector-encoded microrna-based shrna-mediated gene knockdown of n-methyl-d-aspartate receptors in skin reduces pain. | rna polymerase ii promoters that drive the expression of rationally designed primary microrna-based shrna, for example, shrnamir, can produce more potent gene knockdown than rna polymerase iii promoters. antagonists of peripheral n methyl-d-aspartate (nmda) receptors that do not interfere with central glutamate processing would prevent the development of adverse central nervous system effects. thus, in this study, we examined the effects of gene silencing and antinociception on formalin- and com ... | 2017 | 28127509 |
| adam23 is a common risk gene for canine idiopathic epilepsy. | idiopathic or genetic adult-onset epilepsy is a common neurological disorder in domestic dogs. genetic association has been reported only with adam23 on cfa 37 in few breeds. to identify novel epilepsy genes, we performed genome-wide association (gwa) analyses in four new breeds, and investigated the association of the previously reported adam23 haplotype with the epilepsy phenotype in eight breeds. | 2017 | 28143391 |
| circadian preferences in young adults: psychometric properties and factor structure of the portuguese version of the preferences scale (ps-6). | morningness is a trait-like variable which has been extensively studied within chronobiology. despite the number of existing measures to assess morningness, there is a need for brief instruments that are psychometrically sound to be used in applied settings. accordingly, the modified version of the preferences scale (ps-6) comprises six items and was reported to have adequate reliability and satisfactory validity indicators. in this article, the psychometric properties of the portuguese version ... | 2017 | 28139148 |
| formulation of piperine solid lipid nanoparticles (sln) for treatment of rheumatoid arthritis. | the purpose of this work was to formulate piperine solid lipid nanoparticle (sln) dispersion to exploit its efficacy orally and topically. piperine sln were prepared by melt emulsification method and formula was optimized by the application of 3(2) factorial design. the nanoparticulate dispersion was evaluated for particle size, entrapment efficiency and zeta potential (zp). optimized batch (128.80 nm average size, 78.71% entrapment efficiency and -23.34 mv zeta potential) was characterized for ... | 2017 | 28161984 |
| modelling gesture use and early language development in autism spectrum disorder. | nonverbal communication abilities, including gesture use, are impaired in autism spectrum disorder (asd). however, little is known about how common gestures may influence or be influenced by other areas of development. | 2017 | 28120370 |
| the accuracy of a hand-held navigation system in total knee arthroplasty. | this study aims to evaluate the effectiveness of a new hand-held navigation system. the authors of this study hypothesize that this navigation system will improve overall lower limb alignment and implant placement without causing a delay in surgery. | 2017 | 28120025 |
| establishment of a novel autoimmune experimental model of bladder pain syndrome/interstitial cystitis in c57bl/6 mice. | the aim of this study is to identify whether vaccinating twice with bladder homogenate can establish a new model of experimental autoimmune cystitis (eac) in c57bl/6 strain mice. c57bl/6 mice were vaccinated with bladder homogenate in complete freund's adjuvant (cfa) and boost immunized with bladder homogenate in incomplete freund's adjuvant (ifa) after 2 weeks were used as the eac model. mice immunized with phosphate-buffered saline (pbs) in cfa or ifa were used as the control. micturition habi ... | 2017 | 28233078 |
| validation of the children's eating behavior questionnaire in 3 year old children of a multi-ethnic asian population: the gusto cohort study. | the children's eating behaviour questionnaire (cebq) was developed to measure eating behaviors related to obesity risk in children. however, this questionnaire has not been validated for use in south east asia, where parenting practices are different from those in western countries and child obesity rates are increasing. the aim of this study was to examine the validity of the cebq administered to mothers of children aged 3 years in singapore. confirmatory factor analysis (cfa) was used to exami ... | 2017 | 28232104 |
| reexamining the hypoglycemia fear survey for parents of young children in a sample of children using insulin pumps. | we update the psychometric properties of the hypoglycemia fear survey-parents of young children (hfs-pyc), a 26-item measure of parents' hypoglycemia fear for young children using an insulin pump. | 2017 | 28118046 |
| korean translation and validation of the whoqol-dis for people with spinal cord injury and stroke. | the qol assessment to measure disabilities has needed to survey studies for a variety of fields. until now, no korean translation of the world health organization quality of life-disability (whoqol-dis) module existed. | 2017 | 28109695 |
| family food providers' perceptions of the causes of obesity and effectiveness of weight control strategies in five countries in the asia pacific region: a cross-sectional survey. | the rise of the middle classes in developing countries and the associated epidemiological transition raises the importance of assessing this population group's awareness of the causes of obesity and effective weight control strategies in order to develop effective health promotion strategies. the study aimed to examine the perceptions of the causes of obesity and weight control strategies held by middle class household food providers in melbourne, singapore, shanghai, indonesia and vietnam. an o ... | 2017 | 28106781 |
| novel zebrafish eae model: a quick in vivo screen for multiple sclerosis. | pre-clinical drug discovery for multiple sclerosis (ms) is a labor intensive activity to perform in rodent models. this is owing to the long duration of disease induction and observation of treatment effects in an experimental autoimmune encephalomyelitis (eae) model. we propose a novel adult zebrafish based model which offers a quick and simple protocol that can used to screen candidates as a step between in vitro experiments and rodent studies. the experiments conducted for this manuscript wer ... | 2017 | 28104252 |
| the development and validation of the empathy components questionnaire (ecq). | key research suggests that empathy is a multidimensional construct comprising of both cognitive and affective components. more recent theories and research suggest even further factors within these components of empathy, including the ability to empathize with others versus the drive towards empathizing with others. while numerous self-report measures have been developed to examine empathy, none of them currently index all of these wider components together. the aim of the present research was t ... | 2017 | 28076406 |
| feature selection using a one dimensional naïve bayes' classifier increases the accuracy of support vector machine classification of cdr3 repertoires. | somatic dna recombination, the hallmark of vertebrate adaptive immunity, has the potential to generate a vast diversity of antigen receptor sequences. how this diversity captures antigen specificity remains incompletely understood. in this study we use high throughput sequencing to compare the global changes in t cell receptor β chain complementarity determining region 3 (cdr3β) sequences following immunization with ovalbumin administered with complete freund's adjuvant (cfa) or cfa alone. | 2017 | 28073756 |
| compensatory activation of cannabinoid cb2 receptor inhibition of gaba release in the rostral ventromedial medulla in inflammatory pain. | the rostral ventromedial medulla (rvm) is a relay in the descending pain modulatory system and an important site of endocannabinoid modulation of pain. endocannabinoids inhibit gaba release in the rvm, but it is not known whether this effect persists in chronic pain states. in the present studies, persistent inflammation induced by complete freund's adjuvant (cfa) increased gabaergic miniature ipscs (mipscs). endocannabinoid activation of cannabinoid (cb1) receptors known to inhibit presynaptic ... | 2017 | 28100744 |
| psychometric properties of the critical care family needs inventory-emergency department. | the purpose of this study was to test the reliability and validity of the turkish version of the critical care family needs inventory-emergency department (ccfni-ed) in turkey. | 2017 | 28096003 |
| reliability and validity of the turkish version of the rapid estimate of adult literacy in dentistry (treald-30). | to culturally adapt the turkish version of rapid estimate of adult literacy in dentistry (treald-30) for turkish-speaking adult dental patients and to evaluate its psychometric properties. | 2017 | 28093024 |
| spanish adaptation of the frommelt attitude toward care of the dying scale (fatcod-s) in nursing undergraduates. | the frommelt attitude toward care of the dying scale (fatcod) is designed to assess the attitudes of professionals and trainees toward caring for the dying patient and their family members. in this study the main aim is to adapt the fatcod to a spanish context (fatcod-s). in addition, the relations between fatcod-s, sociodemographic variables, emotional intelligence, and death attitudes have been analyzed. a sample of 669 spanish nursing students from four universities responded to a questionnai ... | 2017 | 28092211 |
| electroacupuncture attenuates cfa-induced inflammatory pain by suppressing nav1.8 through s100b, trpv1, opioid, and adenosine pathways in mice. | pain is associated with several conditions, such as inflammation, that result from altered peripheral nerve properties. electroacupuncture (ea) is a common chinese clinical medical technology used for pain management. using an inflammatory pain mouse model, we investigated the effects of ea on the regulation of neurons, microglia, and related molecules. complete freund's adjuvant (cfa) injections produced a significant mechanical and thermal hyperalgesia that was reversed by ea or a transient re ... | 2017 | 28211895 |
| confirmatory factor analysis of the combined social phobia scale and social interaction anxiety scale: support for a bifactor model. | for the social phobia scale (sps) and the social interaction anxiety scale (sias) together, this study examined support for a bifactor model, and also the internal consistency reliability and external validity of the factors in this model. participants (n = 526) were adults from the general community who completed the sps and sias. confirmatory factor analysis (cfa) of their ratings indicated good support for the bifactor model. for this model, the loadings for all but six items were higher on t ... | 2017 | 28210232 |
| arterial access-site complications after use of a vascular closure device related to puncture height. | to analyze differences of access-site complications related to the height of femoral arterial puncture and the use of a vascular closure device (vcd) following percutaneous coronary intervention (pci). | 2017 | 28209184 |
| endovascular treatment of the common femoral artery in the vascular quality initiative. | endovascular interventions of the common (cfa) and deep (dfa) femoral arteries are becoming more common. however, there is very little published data for guidance. our objective was to analyze practice patterns and outcomes from these interventions. | 2017 | 28041804 |
| [xinfeng capsule improves pulmonary function of rats with adjuvant-induced arthritis via regulating the expressions of autophagy-related proteins]. | objective to observe the effect of xinfeng capsule (xfc) on autophagy related gene (atg), microtubule-associated protein 1 light chain 3ii (lc3-ii), beclin 1 in the rat model of adjuvant-induced arthritis (aa). methods rats were divided for four groups: normal control (nc) group, model control (mc) group, leflunomide (lef) group, and xfc group, with 10 rats in each group. complete freund's adjuvant (cfa, 0.1 ml) was injected into the right foot plantar skin of all rats except for the nc group. t ... | 2017 | 28031105 |
| validation of the european cyberbullying intervention project questionnaire for colombian adolescents. | cyberbullying is the act of using unjustified aggression to harm or harass via digital devices. currently regarded as a widespread problem, the phenomenon has attracted growing research interest in different measures of cyberbullying and the similarities and differences across countries and cultures. this article presents the colombian validation of the european cyberbullying intervention project questionnaire (ecipq) involving 3,830 high school students (m = 13.9 years old, standard deviation = ... | 2017 | 28061035 |
| a novel inhibitor of active protein kinase g attenuates chronic inflammatory and osteoarthritic pain. | activating pkg-1α induces a long-term hyperexcitability (lth) in nociceptive neurons. since the lth correlates directly with chronic pain in many animal models, we tested the hypothesis that inhibiting pkg-1α would attenuate lth-mediated pain. we first synthesized and characterized compound n46 (n-((3r,4r)-4-(4-(2-fluoro-3-methoxy-6-propoxybenzoyl)benzamido)pyrrolidin-3-yl)-1h-indazole-5-carboxamide). n46 inhibits pkg-1α with an ic50 of 7.5 nmol, was highly selective when tested against a panel ... | 2017 | 28059868 |
| recovery assessment scale: examining the factor structure of the german version (ras-g) in people with schizophrenia spectrum disorders. | the recovery framework has found its way into local and national mental health services and policies around the world, especially in english speaking countries. to promote this process, it is necessary to assess personal recovery validly and reliably. the recovery assessment scale (ras) is the most established measure in recovery research. the aim of the current study is to examine the factor structure of the german version of the ras (ras-g). | 2017 | 28049083 |
| what to do when scalar invariance fails: the extended alignment method for multi-group factor analysis comparison of latent means across many groups. | scalar invariance is an unachievable ideal that in practice can only be approximated; often using potentially questionable approaches such as partial invariance based on a stepwise selection of parameter estimates with large modification indices. study 1 demonstrates an extension of the power and flexibility of the alignment approach for comparing latent factor means in large-scale studies (30 oecd countries, 8 factors, 44 items, n = 249,840), for which scalar invariance is typically not support ... | 2017 | 28080078 |
| peptide from sea anemone metridium senile affects transient receptor potential ankyrin-repeat 1 (trpa1) function and produces analgesic effect. | the transient receptor potential ankyrin-repeat 1 (trpa1) is an important player in pain and inflammatory pathways. it is a promising target for novel drug development for the treatment of a number of pathological states. a novel peptide producing a significant potentiating effect on allyl isothiocyanate- and diclofenac-induced currents of trpa1 was isolated from the venom of sea anemone metridium senile. it is a 35-amino acid peptide cross-linked by two disulfide bridges named τ-anmtx ms 9a-1 ( ... | 2017 | 28077580 |
| cutting edge: adenosine a2a receptor signals inhibit germinal center t follicular helper cell differentiation during the primary response to vaccination. | adenosine a2a receptor (a2ar) signaling acts as a barrier to autoimmunity by promoting anergy, inducing regulatory t cells, and inhibiting effector t cells. however, in vivo effects of a2ar signaling on polyclonal cd4 t cells during a primary response to foreign ag has yet to be determined. to address this problem, we immunized mice with peptide ag 2w1s coupled to pe in cfa and treated with the selective a2ar agonist cgs-21680 (cgs). 2w1s:i-a(b)-specific tetramer-binding cd4 t cells did not beco ... | 2017 | 27986907 |
| engagement in and continuity of hiv care among african and caribbean black women living with hiv in ontario, canada. | engagement in care is a key component of the hiv care cascade, yet there are knowledge gaps regarding how to assess hiv care engagement. this study aimed to develop a tool to assess hiv care engagement and to assess associations between hiv care engagement and quality of life (qol) among african, caribbean and black (acb) women living with hiv (wlwh). we conducted a cross-sectional survey with acb wlwh across ontario, canada. we developed the 'hiv engagement in and continuity of care scale' (hec ... | 2017 | 27956646 |
| urinary metabolomics of complete freund's adjuvant-induced hyperalgesia in rats. | the aim of this study was to demonstrate the differences of metabolomics changes in a hyperalgesia model and find potent biomarkers of hyperalgesia. seven rats were placed in metabolic cages. an emulsion containing 500 μg of complete freund's adjuvant (cfa) was used to induce hyperalgesia. urine samples were collected prior to the injection of cfa and on post-injection days 1, 3 and 7. ultraperformance liquid chromatography, coupled with quadrupole-time-of-flight mass spectrometry (uhplc-q-tof/m ... | 2017 | 28058725 |
| cross-cultural validity of morningness-eveningness stability scale improved (messi) in iran, spain and germany. | morningness-eveningness stability scale improved (messi) is a newly constructed measure to assess circadian types and amplitude. in this study, we applied this measure to participants from three different countries: germany, spain and iran. confirmatory factorial analysis (cfa) of messi displayed mediocre fit in the three countries. comparing increasingly stringent models using multigroup confirmatory factor analyses indicated at least partial measurement invariance (metric invariance) by countr ... | 2017 | 28055262 |
| psychometric evaluation of the finnish version of the impact on participation and autonomy questionnaire in persons with multiple sclerosis. | the objective of this study was to evaluate the psychometric properties of the impact on participation and autonomy (ipa) questionnaire. the finnish version of ipa (ipafin) was translated into finnish using the protocol for linguistic validation for patient-reported outcomes instruments. | 2017 | 28049364 |
| international development and psychometric properties of the child and adolescent trauma screen (cats). | systematic screening is a powerful means by which children and adolescents with posttraumatic stress symptoms (ptss) can be detected. reliable and valid measures based on current diagnostic criteria are needed. | 2017 | 28049104 |
| spinal intracellular metabotropic glutamate receptor 5 (mglur5) contributes to pain and c-fos expression in a rat model of inflammatory pain. | metabotropic glutamate receptor 5 (mglur5) is an excitatory g-protein-coupled receptor (gpcr) present in the spinal cord dorsal horn (scdh) where it has a well-established role in pain. in addition to its traditional location on the cytoplasmic membrane, recent evidence shows that these receptors are present intracellularly on the nuclear membrane in the spinal cord dorsal horn and are implicated in neuropathic pain. nuclear mglur5 is a functional receptor that binds glutamate entering the cell ... | 2017 | 28030475 |
| agmatine ameliorates adjuvant induced arthritis and inflammatory cachexia in rats. | the present study investigated the pharmacological effect of agmatine in complete freud adjuvant (cfa) induced arthritis and cachexia in rats. the rats were injected with cfa (0.1ml/rat) to induced symptoms of arthritis. day 8 onwards of cfa administration, rats were injected daily with agmatine for next 7days, and arthritis score, body weights and food intake were monitored daily (g). since cachexia is known to produce severe inflammation, malnutrition and inhibition of albumin gene expression, ... | 2017 | 28006753 |
| testing event-based forms of causality. | three fundamental types of causal relations are those of necessity, sufficiency, and necessity and sufficiency. these types are defined in contexts of categorical variables or events. using statement calculus or boolean algebra, one can determine which patterns of events are in support of a particular form of causal relation. in this article, we approach the analysis of these forms of causality taking the perspective of the analyst of empirical data. it is proposed using configural frequency ana ... | 2017 | 28092016 |
| evaluation of microrna stability in plasma and serum from healthy dogs. | early and specific detection of cancer is of great importance for successful treatment of the disease. new biomarkers, like micrornas, could improve treatment efficiency and survival ratio. in human medicine, deregulation of microrna profiles in circulation has shown great potential as a new type of biomarker for cancer diagnostics. there are, however, few studies of circulating micrornas in dogs. extracellular circulating micrornas have shown a high level of stability in human blood and other b ... | 2017 | 28088915 |
| translation, cross-cultural adaption and measurement properties of the evidence-based practice profile. | the evidence-based practice profile (ebp(2)) questionnaire assesses students' self-reported knowledge, behaviour and attitudes related to evidence-based practice. the aim of this study was to translate and cross-culturally adapt ebp(2) into norwegian and to evaluate the reliability, validity and responsiveness of the norwegian version. | 2017 | 28086967 |
| psychometric properties of the finnish version of the young person's clinical outcomes in routine evaluation (yp-core) questionnaire. | an increasing need exists for suitable measures to evaluate treatment outcome in adolescents. yp-core is a pan-theoretical brief questionnaire developed for this purpose, but it lacks studies in different cultures or languages. | 2017 | 28084134 |
| validity and reliability of the positive aspects of caregiving (pac) scale and development of its shorter version (s-pac) among family caregivers of older adults. | to (a) assess the validity and reliability of the 9-item positive aspects of caregiving (pac) scale among a national sample of caregivers for older adults with functional limitations, (b) develop a shorter version (short-pac [s-pac] scale) and assess its psychometric properties, and (c) investigate both scales' measurement equivalence/invariance (me/i) across language of administration (chinese/english/malay). | 2017 | 28082275 |
| fin-tiera: a tool for assessing technology induced errors. | due to the complexity of healthcare processes, the potential for health information systems (his) to cause technology-induced errors is a growing concern. health information technology (hit) errors nearly always threaten good patient care and can lead to patient harm. instruments to allow hospitals to proactively identify areas of electronic health records (ehr) safety, to set priorities and to intervene before incidents occur are currently underdeveloped. | 2017 | 27922661 |
| efficacy of pancreatic enzyme replacement therapy in chronic pancreatitis: systematic review and meta-analysis. | the benefits of pancreatic enzyme replacement therapy (pert) in chronic pancreatitis (cp) are inadequately defined. we have undertaken a systematic review and meta-analysis of randomised controlled trials of pert to determine the efficacy of pert in exocrine pancreatic insufficiency (epi) from cp. | 2017 | 27941156 |
| minimal impact of response shift for sf-12 mental and physical health status in homeless and vulnerably housed individuals: an item-level multi-group analysis. | the purpose of this study was to examine whether homeless or vulnerably housed individuals experienced response shift over a 12-month time period in their self-reported physical and mental health status. | 2017 | 27933427 |
| factor analyses for the örebro musculoskeletal pain questionnaire for working and nonworking patients with chronic low back pain. | the örebro musculoskeletal pain questionnaire (ömpq) has good psychometric properties to predict return to work in patients with acute low back pain. although it is used in patients with chronic back pain and nonworkers, there is no evidence on the factor structure of the ömpq in these populations. this is deemed an important prerequisite for future prediction studies. | 2017 | 27916683 |
| using hospital anxiety and depression scale (hads) on patients with epilepsy: confirmatory factor analysis and rasch models. | the problems of mood disorders are critical in people with epilepsy. therefore, there is a need to validate a useful tool for the population. the hospital anxiety and depression scale (hads) has been used on the population, and showed that it is a satisfactory screening tool. however, more evidence on its construct validity is needed. | 2017 | 27915110 |
| bilateral increases in erk activation at the spinomedullary junction region by acute masseter muscle injury during temporomandibular joint inflammation in the rats. | we determined the role of persistent monoarthritis of temporomandibular joint region (tmj) on bilateral masseter muscle (mm) nociception in male rats using orofacial nocifensive behaviors, phosphorylated extracellular signal-regulated kinase and fos induction at the trigeminal subnucleus caudalis/upper cervical spinal cord (vc/c2) region in response to formalin injection to the mm region. tmj inflammation was induced by local injection of cfa into the left tmj region. orofacial nocifensive behav ... | 2017 | 27933357 |
| a novel approach for the control of inflammatory pain: prostaglandin e2 complexation by randomly methylated β-cyclodextrins. | inhibitors of cyclooxygenase, which block the formation of prostaglandin (pg) e2, are the standard treatment of inflammatory pain. these drugs, however, have serious gastrointestinal, renal, and cardiovascular side effects that limit their clinical use. cyclodextrins are neutral glucose oligomers that form a hydrophilic outer and a hydrophobic interior cavity used to carry hydrophilic substances. methyl-β-cyclodextrins are used currently in several drugs as enhancers and also to deliver pgs. we ... | 2017 | 27930390 |
| psychological adjustment to craniofacial conditions (excluding oral clefts): a review of the literature. | a congenital craniofacial anomaly (cfa) is expected to impact upon several domains of psychological, emotional and social functioning, yet no recent reviews have comprehensively summarised the available literature. further, existing reviews tend to draw upon literature in the field of cleft lip and palate, and do not give substantive attention to other types of cfas. | 2017 | 27925479 |
| long-term outcomes of common femoral artery stenting. | the purpose of this study was to report the 5-year outcome relative to endovascular repair of the common femoral artery (cfa) for occlusive disease. | 2017 | 27903480 |
| development and measurement properties of the chinese breastfeeding self-regulation questionnaire. | although new mothers are aware of the benefits of breastfeeding, many of them stop breastfeeding early in the postpartum period. maternal psychosocial factors have been shown to contribute to early breastfeeding cessation. according to self-determination theory (sdt) maternal self-determination is an indispensable factor in studying motivation to breastfeed. there are no validated instruments to assess maternal breastfeeding motivation and self-determination. | 2017 | 27889680 |
| the chinese version of instrument of professional attitude for student nurses (ipasn): assessment of reliability and validity. | professional attitude is of great importance for nursing talents in the modern society. to develop an effective educational program for student nurses in china, an appropriate instrument is required for the assessment of their professional attitude. | 2017 | 27889582 |
| cool and hot aspects of executive function in childhood obsessive-compulsive disorder. | aspects of executive functioning (ef) have been put forward as endophenotypes in obsessive- compulsive disorder (ocd) and meta-analyses support ef underperformance in adult samples. childhood-onset ocd has been suggested to constitute a separate neurodevelopmental subtype of the disorder but studies on neuropsychological functioning in childhood ocd are limited. the aim of the present study was to investigate performance-based ef in pediatric ocd using observed and latent variable analyses. a ca ... | 2017 | 27838893 |
| a multimethod latent state-trait model for structurally different and interchangeable methods. | a new multiple indicator multilevel latent state-trait (lst) model for the analysis of multitrait-multimethod-multioccasion (mtmm-mo) data is proposed. the lst-com model combines current cfa-mtmm modeling approaches of interchangeable and structurally different methods and lst modeling approaches. the model enables researchers to specify construct and method factors on the level of time-stable (trait) as well as time-variable (occasion-specific) latent variables and analyze the convergent and di ... | 2017 | 27905055 |
| cardamonin (2',4'-dihydroxy-6'-methoxychalcone) isolated from boesenbergia rotunda (l.) mansf. inhibits cfa-induced rheumatoid arthritis in rats. | boesenbergia rotunda (l.) mansf. had been traditionally used as herbs to treat pain and rheumatism. cardamonin (2',4'-dihydroxy-6'-methoxychalcone) is a compound isolated from boesenbergia rotunda (l.) mansf.. previous study had shown the potential of cardamonin in inhibiting the release of pro-inflammatory cytokines such as tumour necrosis factor-α (tnf-α), interleukin-1β (il-1β), and interleukin-6 (il-6) in vitro. thus, the possible therapeutic effect of cardamonin in the rheumatoid arthritis ... | 2017 | 27845065 |
| vendor-derived differences in injury-induced pain phenotype and pharmacology of sprague-dawley rats: does it matter? | outbred sprague-dawley (sd) rats are a commonly used strain in preclinical pain research. here, we established empirically how sd rats obtained from different vendors might vary in sensitivity to injury and pharmacotherapy. | 2017 | 27805755 |
| intra-articular injection of botulinum toxin a reduces neurogenic inflammation in cfa-induced arthritic rat model. | currently, administration of botulinum toxin type a (bont/a) to treat arthritic pain has promising efficacy in clinical research. however, the mechanisms underlying anti-neurogenic inflammation mediated by bont/a remains unclear. the aim of this study was to demonstrate the effectiveness in macro and micro levels and to explore the causal mechanism of bont/a. wistar rats (n = 60) were injected with 50ul complete freund's adjuvant (cfa) in the left ankle joint capsule to establish a model of chro ... | 2017 | 27838288 |
| adjustment disorder: empirical study of a new diagnostic concept for icd-11 in the general population in lithuania. | adjustment disorder (ad) is one of the most debated diagnoses in psychiatry since it has been recognised as vaguely defined and causing a lot of difficulties in clinical practice. we aimed to analyse the structure of adjustment disorder based on international classification of diseases (icd)-11 proposals by the who icd-11 working group on the classification of disorders specifically associated with stress in the general population in lithuania. three structural models of adjustment disorder were ... | 2017 | 27837668 |
| the effects of sex and gender-role characteristics on facets of sociosexuality in heterosexual young adults. | the present study was designed to systematically investigate the functional relationships among biological sex; masculine and feminine gender-role characteristics; and sociosexual behavior, attitude toward, and desire for uncommitted casual sex as three facets of sociosexual orientation. for this purpose, facets of sociosexuality were assessed by the revised sociosexual orientation inventory (soi-r) and masculine and feminine gender-role characteristics were assessed by a revised german version ... | 2017 | 27834495 |
| impacts of regional transport on black carbon in huairou, beijing, china. | the 22(nd) asia-pacific economic cooperation (apec) conference was held near yanqi lake, huairou, in beijing, china during november 10-11, 2014. to guarantee haze-free days during the apec conference, the beijing government and the governments of the surrounding provinces implemented a series of controls. three months of aethalometer 880 nm black carbon (bc) measurements were examined to understand the hourly fluctuations in bc concentrations that resulted from emission controls and meteorology ... | 2017 | 27889086 |
| the roland-morris disability questionnaire: one or more dimensions? | the roland-morris disability questionnaire (rmdq) is one of the most recommended questionnaires to assess disability. some previous studies support the assumption that the rmdq is a unidimensional measure; however, recent studies have suggested that this measure has more than one domain and should be considered as a multidimensional scale. therefore, the aim of this study was to analyse the structure of the rmdq in a large sample of patients with low back pain using two different statistical app ... | 2017 | 27885478 |
| internal consistency, convergent validity, and structural validity of the japanese version of the physical activity self-regulation scale (pasr-12) among japanese workers: a validation study. | self-regulation for physical activity is considered as one of the most effective factors in promoting physical activity. however, there is no reliable and valid scale to measure it in japanese. the purpose of this study was to investigate the internal consistency, convergent validity, and structural validity of the newly developed japanese version of the 12-item physical activity self-regulation scale (pasr-12) among japanese workers. | 2017 | 27885244 |
| factor structure of sizing me up, a self-reported weight-related quality of life instrument, in community children across weight status. | to further understand the psychometric properties of the sizing me up-a newly developed quality of life (qol) instrument related to weight status. we extended the target population to a community sample, including obese, overweight, normal-weight, and underweight children. | 2017 | 27996301 |
| incorporation of conjugated fatty acids into nile tilapia (oreochromis niloticus). | the aim of this work was to improve the nutritional quality of nile tilapia meat through enriched diets with conjugated isomers of linolenic acid from tung oil. the transfer process of conjugated fatty acids (cfas) into fish muscle tissue was evaluated by gas chromatography-flame ionization detection (gc-fid) and easy ambient sonic-spray ionization mass spectrometry (easi-ms). | 2017 | 27873315 |
| inhibitory effect of estrogen receptor beta on p2x3 receptors during inflammation in rats. | estrogen receptor beta (erβ) has been shown to play a therapeutic role in inflammatory bowel disease (ibd). however, the mechanism underlying how erβ exerts therapeutic effects and its relationship with p2x3 receptors (p2x3r) in rats with inflammation is not known. in our study, animal behavior tests, visceromotor reflex recording, and western blotting were used to determine whether the therapeutic effect of erβ in rats with inflammation was related with p2x3r. in complete freund adjuvant (cfa)- ... | 2017 | 27817132 |
| translation and validation of the thai version of a modified brief pain inventory: a concise instrument for pain assessment in postoperative cardiac surgery. | acute pain after cardiac surgery can be assessed using validated instruments such as the modified interference subscale of the brief pain inventory (mod-bpi). despite the available knowledge, the thai version of a mod-bpi has not yet been presented. | 2017 | 27676458 |
| concept mapping as an approach for expert-guided model building: the example of health literacy. | concept mapping served as the starting point for the aim of capturing the comprehensive structure of the construct of 'health literacy.' ideas about health literacy were generated by 99 experts and resulted in 105 statements that were subsequently organized by 27 experts in an unstructured card sorting. multidimensional scaling was applied to the sorting data and a two and three-dimensional solution was computed. the three dimensional solution was used in subsequent cluster analysis and resulted ... | 2017 | 27771012 |
| reliability and validity of the japanese version of the emotion regulation skills questionnaire. | the emotion regulation skills questionnaire (ersq) comprehensively assesses nine aspects of emotion regulation skills: awareness, clarity, sensation, understanding, compassionate self-support, modification, acceptance, tolerance, and readiness to confront. however, it is unknown about the levels of emotion regulation skills in various mental disorders, and its cross-cultural validity. we developed a japanese version of the ersq, then examined its validity and reliability in clinical and non-clin ... | 2017 | 27770644 |
| validation of a latent construct for dementia in a population-wide dataset from singapore. | the latent variable δ has been proposed as a proxy for dementia. previous validation studies have been conducted using convenience samples. it is currently unknown how δ performs in population-wide data. | 2017 | 27802230 |
| testing the psychometric properties of kidscreen-27 with irish children of low socio-economic status. | kidscreen-27 was developed as part of a cross-cultural european union-funded project to standardise the measurement of children's health-related quality of life. yet, research has reported mixed evidence for the hypothesised 5-factor model, and no confirmatory factor analysis (cfa) has been conducted on the instrument with children of low socio-economic status (ses) across ireland (northern and republic). | 2017 | 27757774 |
| validation of a brief insomnia severity measure in youth clinically referred for sleep evaluation. | evaluate psychometric properties of the pediatric insomnia severity index (pisi), a brief measure of insomnia severity. | 2017 | 27694574 |
| ventral striatum and amygdala activity as convergence sites for early adversity and conduct disorder. | childhood family adversity (cfa) increases the risk for conduct disorder (cd) and has been associated with alterations in regions of affective processing like ventral striatum (vs) and amygdala. however, no study so far has demonstrated neural converging effects of cfa and cd in the same sample. at age 25 years, functional mri data during two affective tasks, i.e. a reward (n = 171) and a face-matching paradigm (n = 181) and anatomical scans (n = 181) were acquired in right-handed currently heal ... | 2017 | 27694318 |
| analysis of inflammation-induced depression of home cage wheel running in rats reveals the difference between opioid antinociception and restoration of function. | opioids are effective at inhibiting responses to noxious stimuli in rodents, but have limited efficacy and many side effects in chronic pain patients. one reason for this disconnect is that nociception is typically assessed using withdrawal from noxious stimuli in animals, whereas chronic pain patients suffer from abnormal pain that disrupts normal activity. we hypothesized that assessment of home cage wheel running in rats would provide a much more clinically relevant method to assess opioid ef ... | 2017 | 27746208 |
| confirmatory factor analysis of the quality of life scale and new proposed factor structure for the quality of life scale-revised. | the quality of life scale (qls) is a frequently used semistructured interview for the assessment of functional outcomes in schizophrenia. despite the use of the qls for over 30years, the original 4-factor structure of the instrument (interpersonal relations, instrumental role, intrapsychic foundations, and common objects and activities) has not been rigorously examined. exploratory factor analyses (efas) and confirmatory factor analyses (cfas) were used to evaluate the factor structure of the ql ... | 2017 | 27756514 |
| pulsed radiofrequency attenuates complete freund's adjuvant-induced epigenetic suppression of potassium chloride cotransporter 2 expression. | pulsed radiofrequency (prf) treatment offers pain relief for patients suffering from chronic pain who do not respond well to conventional treatments. we tested whether prf treatment attenuated complete freund's adjuvant (cfa)-induced inflammatory pain. epigenetic modification of potassium-chloride cotransporter 2 (kcc2) gene expression was examined to elucidate the potential contributing mechanism. | 2017 | 27688312 |
| α5gabaa receptors mediate tonic inhibition in the spinal cord dorsal horn and contribute to the resolution of hyperalgesia. | neuronal inhibition mediated by gabaa receptors constrains nociceptive processing in the spinal cord, and loss of gabaergic inhibition can produce allodynia and hyperalgesia. extrasynaptic α5 subunit-containing gabaa receptors (α5gabaa rs) generate a tonic conductance that inhibits neuronal activity and constrains learning and memory; however, it is unclear whether α5gabaa rs similarly generate a tonic conductance in the spinal cord dorsal horn to constrain nociception. we assessed the distribut ... | 2017 | 27792253 |
| development of a measure to evaluate gains among spanish dementia caregivers: the gains associated with caregiving (gac) scale. | the study is aimed at developing a new measure devised to evaluate gains associated with caregiving for a person with dementia. | 2017 | 27668548 |
| the superficial femoral artery: an alternative access for percutaneous endovascular aneurysm repair. | the aim of this study was to report the results of percutaneous endovascular aortic aneurysm repair (pevar) using the superficial femoral artery (sfa) for large bore vessel access. | 2017 | 27666800 |
| spinal cord injury suppresses cutaneous inflammation: implications for peripheral wound healing. | people who suffer a traumatic spinal cord injury (sci) are at increased risk for developing dermatological complications. these conditions increase cost of care, incidence of rehospitalization, and the risk for developing other infections. the consequences of dermatological complications after sci are likely exacerbated further by post-injury deficits in neural-immune signaling. indeed, a functional immune system is essential for optimal host defense and tissue repair. here, we tested the hypoth ... | 2017 | 27650169 |
| development of short-form and screening cutoff point of the smartphone addiction inventory (spai-sf). | smartphone addiction is considered a form of technological addiction that has attracted increasing attention. the present study developed and validated the short-form smartphone addiction inventory (spai-sf) and established cutoff point for screening smartphone addiction based on diagnostic criteria established by psychiatric interview. a total of 268 participants completed an online survey that collected demographic data, smartphone use behaviours, and responses to the 26-item spai. each partic ... | 2017 | 27658956 |
| development of the participation measure-3 domains, 4 dimensions (pm-3d4d): a new outcome measure for rehabilitation. | to describe the development of a participation measure that assesses 3 domains (productivity, social, and community) and 4 dimensions (frequency, diversity, desire for change, and perceived difficulty) of participation and to evaluate the initial psychometric properties in rehabilitation outpatients. | 2017 | 27594516 |
| the conceptualization and measurement of cognitive reserve using common proxy indicators: testing some tenable reflective and formative models. | the examination of cognitive reserve (cr) literature reveals a lack of consensus regarding conceptualization and pervasive problems with its measurement. this study aimed at examining the conceptual nature of cr through the analysis of reflective and formative models using eight proxies commonly employed in the cr literature. we hypothesized that all cr proxies would significantly contribute to a one-factor reflective model and that educational and occupational attainment would produce the stron ... | 2017 | 27647132 |
| impaired development and dysfunction of endothelial progenitor cells in type 2 diabetic mice. | dysfunction of circulating endothelial progenitor cells (epcs) has been shown to affect the development of microvascular diseases in diabetes patients. the aim of this study was to elucidate the development and mechanical dysfunction of epcs in type 2 diabetes (t2d). | 2017 | 27638126 |
| measuring burden in dementia caregivers: confirmatory factor analysis for short forms of the zarit burden interview. | to examine the psychometric properties of different short versions of the zarit burden interview (zbi), and to find an efficient and valid short version for clinical use among dementia caregivers. | 2017 | 27580015 |
| patient perceptions of deprescribing: survey development and psychometric assessment. | although clinicians ultimately decide when to discontinue (deprescribe) medications, patients' perspectives may guide the process. | 2017 | 27579916 |
| defining the common femoral artery: insights from the femoral arterial access with ultrasound trial. | we sought to establish the typical location of the common femoral artery (cfa) bifurcation, the origin and most inferior reflection of the inferior epigastric artery (iea) relative to the femoral head (fh) and whether patient demographics predicted anatomical variations. | 2017 | 27566991 |
| reaction pathway mechanism of thermally induced isomerization of 9,12-linoleic acid triacylglycerol. | to clarify the formation mechanism of trans linoleic acid isomers in edible oils during the heating process, trilinolein and trilinoelaidin, as representative oils, were placed in glass ampoules and sealed before heating at 180, 240 and 320 °c. the glass ampoules were removed at regular time intervals, and the contents were analyzed by infrared spectroscopy. the samples were then subjected to derivatization into their methyl esters for gas chromatographic analysis. | 2017 | 27507439 |
| epigenetic suppression of potassium-chloride co-transporter 2 expression in inflammatory pain induced by complete freund's adjuvant (cfa). | multiple mechanisms contribute to the stimulus-evoked pain hypersensitivity that may be experienced after peripheral inflammation. persistent pathological stimuli in many pain conditions affect the expression of certain genes through epigenetic alternations. the main purpose of our study was to investigate the role of epigenetic modification on potassium-chloride co-transporter 2 (kcc2) gene expression in the persistence of inflammatory pain. | 2017 | 27506893 |
| validation of world health organization assessment schedule 2.0 in specialized somatic rehabilitation services in norway. | the world health organization disability assessment schedule (whodas) 2.0 is a generic instrument to assess disability covering six domains. the purpose of this study was to investigate the potential of the instrument for monitoring disability in specialized somatic rehabilitation by testing reliability, construct validity and responsiveness of whodas 2.0, norwegian version, among patients with various health conditions. | 2017 | 27506525 |
| sinomenine attenuates chronic inflammatory pain in mice. | sinomenine, an alkaloid originally isolated from the roots of sinomeniumacutum, is used as a traditional chinese medicine for rheumatic arthritis. however, little is known about the neuronal mechanisms underlying the analgesic effects of sinomenine in animals with chronic inflammatory pain. in this study, we investigated the persistent inflammatory pain induced by hind paw injection of complete freund's adjuvant (cfa) in mice, which was reversed by sinomenine administration. in the anterior cing ... | 2017 | 27585465 |
| nociception contributes to the formation of myogenic contracture in the early phase of adjuvant-induced arthritis in a rat knee. | it is unknown how joint contracture is generated in inflamed joints. this study aimed to clarify the role of nociception on the formation of joint contracture secondary to arthritis. monoarthritis was induced by intra-articular injections of complete freund's adjuvant (cfa) into rat knees. on day 5 after cfa injection, the passive extension range of motion (rom) of knee joints were measured, both before and after myotomy of knee flexors, to evaluate the extent of muscular contribution to cfa-ind ... | 2017 | 27584936 |
| diminished il-17a levels may protect filarial-infected individuals from development of rheumatoid arthritis and systemic lupus erythematosus. | nematode infections have been observed to inversely correlate with autoimmune disorders. recently, we have shown the absence of filarial infection in patients with rheumatoid arthritis (ra) and systemic lupus erythematosus (sle) who live in filarial-endemic areas. the mechanism(s) by which filarial-infected individuals are protected against the development of ra or sle are unknown. in mice cia, an experimental model for ra, es-62, an execratory product of rodent filarial nematode , has been show ... | 2017 | 27488471 |
| lps-matured cd11c+ bone marrow-derived dendritic cells can initiate autoimmune pathology with minimal injection site inflammation. | the pathogenesis of human autoimmune disorders is incompletely understood. this has led to the development of numerous murine models in which the pathogenesis of autoimmunity can be probed and the efficacy of novel therapies can be tested. one of the most widely-used murine models of autoimmunity is experimental autoimmune encephalomyelitis (eae). to induce autoimmune pathology, mice are often immunized with an autoantigen alongside an adjuvant, typically complete freund's adjuvant (cfa). unfort ... | 2017 | 27488372 |