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associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the canary islands.the single nucleotide polymorphism (snp) lct -13910 c>t, associated with genetically determined phenotypes of lactase persistence (lp) or non-persistence (lnp), was studied in relation to the metabolic syndrome (ms).201019844753
an examination of amphibian sensitivity to environmental contaminants: are amphibians poor canaries?nearly two decades ago, the global biodiversity crisis was catapulted to the front pages of newspapers with the recognition of worldwide amphibian declines. amphibians earned their appellation, 'canaries in a coal mine', because of apparent high sensitivity to human-mediated environmental change. the most frequently cited causes for high susceptibility include permeable skin, a dual aquatic-terrestrial life cycle and a relatively rudimentary immune system. while some researchers have questioned ...201019845728
heavy and trace metal concentrations in three rockpool shrimp species (palaemon elegans, palaemon adspersus and palaemon serratus) from tenerife (canary islands).trace metal concentrations (fe, cu, co, zn, ni and v) were investigated in three rockpool shrimp species (palaemon elegans, palaemon adspersus and palaemon serratus) from six littoral sampling sites (polluted and non-polluted) of tenerife in the canary islands (central eastern atlantic), spain. sex ratio for all three species has been determined: females predominate over males in all species and significant differences in total length and cephalothorax length was detected between sexes, being fe ...201019685272
canary prostate active surveillance study: design of a multi-institutional active surveillance cohort and biorepository.active surveillance is a management plan for localized prostate cancer that offers selective delayed intervention on indication of disease progression, allowing patients to delay or avoid treatment and associated side-effects. outcomes from centers that promote active surveillance are favorable, with high rates of disease-specific survival. however, there remains a need for prognostic variables or biomarkers that distinguish with high specificity the aggressive cancers that progress on surveilla ...201019758683
accumulation of toxic metals (pb and cd) in the sea urchin diadema aff. antillarum philippi, 1845, in an oceanic island (tenerife, canary islands).this document shows the results obtained from a study on the concentration of toxic heavy metals in the internal tissue and exoskeleton of sea urchins, collected from their natural habitat. the levels of lead and cadmium were measured by graphite furnace atomic absorption spectrometry. the mean concentrations of lead and cadmium in the internal tissue were 304.04 and 260.54 microg/kg respectively, whereas in the shell they were 185.02 and 142.48 microg/kg. we also performed a statistical analysi ...201019399849
insulin-like growth factor-i (igf-i) serum concentrations in healthy children and adolescents: relationship to level of contamination by ddt-derivative pesticides.serum levels of insulin-like growth factor i (igf-i) play a critical role in children growth and in the pathogenesis of several diseases. in addition, recent studies suggest that ddt-derivative organochlorine pesticides (oc-ddts) could influence igf levels in human beings.201019699127
determinants of health care costs of hiv-positive patients in the canary islands, spain.the aims of this study were to estimate medical expenditures on human immunodeficiency virus (hiv) treatment and to identify significant associated variables. we performed a retrospective multi-centre study in the canary islands using a sample of 569 patients recruited at outpatient visits. the study examined demographic and clinical variables, health-related quality of life (hrqol), and health care resources. clinical data was obtained from medical records and patient interviews. several empiri ...201020049503
disproportionately high incidence of diabetes-related end-stage renal disease in the canary islands. an analysis based on estimated population at risk.an exceptionally high incidence of diabetes-related end-stage renal disease (dm-esrd) has been reported in the canary islands. this phenomenon was attributed to an increased prevalence of diabetes in this community. we compared the incidence of dm-esrd in the canary islands with the rest of spain among the estimated number of individuals at risk (people with diabetes in the population).201020064954
a canary in the coal mine: documenting citizenship and identity in the state of massachusetts.the u.s. federal government requires original documentation of citizenship and identity for applicants to qualify for coverage under medicaid. the purpose of this investigation is to identify what challenges one state medicaid agency has faced when implementing this requirement; and to identify what strategies this agency and other interested parties (e.g., providers, community advocates) adopted to help overcome them.201020074830
health information exchange, biosurveillance efforts, and emergency department crowding during the spring 2009 h1n1 outbreak in new york city.novel h1n1 influenza spread rapidly around the world in spring 2009. few places were as widely affected as the new york metropolitan area. emergency departments (eds) in the region experienced daily visit increases in 2 distinct temporal peaks, with means of 36.8% and 60.7% over baseline in april and may, respectively, and became, in a sense, the "canary in the coal mine" for the rest of the country as we braced ourselves for resurgent spread in the fall. biosurveillance efforts by public health ...201020079955
chemotaxonomy of gonospermum and related genera.aerial parts of gonospermum fruticosum collected at several locations in the canary islands afforded, in addition to known compounds, four sesquiterpene alcohols related to costol and a sesquiterpene lactone, whose structures were established on the basis of their spectroscopic data and chemical transformations. except for gonospermum species collected on the island of tenerife, those collected on the island of el hierro and, in a previous study those from la gomera, contain sesquiterpene lacton ...201020096903
innovative individuals are not always the best demonstrators: feeding innovation and social transmission in serinus canaria.feeding innovation occurs when individuals choose a novel, unknown type of food and/or acquire new feeding skills. here we studied feeding innovation and social transmission of the new feeding habit in canaries. adult canaries eat a wide variety of seeds but avoid larger ones such as those of sunflowers. we determined whether adults of both sexes are equally prone to innovate when confronted with sunflower seeds and whether free-interactions facilitate transmission of the new feeding habit in a ...201020111590
[glove perforation in surgery and protective effect of double gloves].to investigate the incidence of glove perforation in programmed surgery and compare perforation rates between single-gloves and double-gloves. to evaluate the extent to which glove perforations remain undetected during surgery.201020116312
strains nodulating lupinus albus on different continents belong to several new chromosomal and symbiotic lineages within bradyrhizobium.in this work we analysed different chromosomal and symbiotic markers in rhizobial strains nodulating lupinus albus (white lupin) in several continents. collectively the analysis of their rrs and atpd genes, and 16s-23s intergenic spacers (its), showed that they belong to at least four chromosomal lineages within the genus bradyrhizobium. most isolates from the canary islands (near to the african continent) grouped with some strains isolated on mainland spain and were identified as bradyrhizobium ...201020135225
mine wastewater treatment using phalaris arundinacea plant material hydrolyzate as substrate for sulfate-reducing bioreactor.a low-cost substrate, phalaris arundinacea was acid hydrolyzed (reed canary grass hydrolyzate, rcgh) and used to support sulfate reduction. the experiments included batch bottle assays (35 degrees c) and a fluidized-bed bioreactor (fbr) experiment (35 degrees c) treating synthetic mine wastewater. dry plant material was also tested as substrate in batch bottle assays. the batch assays showed sulfate reduction with the studied substrates, producing 540 and 350mgl(-1) dissolved sulfide with rcgh a ...201020137922
air pollution and mortality in the canary islands: a time-series analysis.the island factor of the cities of las palmas de gran canaria and santa cruz de tenerife, along with their proximity to africa and their meteorology, create a particular setting that influences the air quality of these cities and provides researchers an opportunity to analyze the acute effects of air-pollutants on daily mortality.201020152037
finding of parastrongylus cantonensis (chen, 1935) in rattus rattus in tenerife, canary islands (spain).parastrongylus cantonensis is a parasite of murid rodents that can infect humans and cause health problems as eosinophilic meningitis. although it is endemic in south asia, the pacific islands, australia, usa, and a few caribbean islands, it has been extended to new geographical regions. in the canary islands (spain) a survey of helminths of rattus rattus, rattus norvegicus and mus musculus domesticus was carried out. furthermore, five species of molluscs were examined for nematode larvae to det ...201020153283
[seasonal influence in characteristics of patients admitted to an intensive care unit].to investigate seasonal variability in the epidemiology and the outcome of critical illness.201020156706
twins switched at birth: a case from the canary islands.monozygotic (mz) twins switched at birth represent a rare class of twins who are reared apart and reunited (mza). background data and descriptive findings from a case study of such a pair, born thirty-six years ago in the canary islands, are presented.201020158315
area-specific migration and recruitment of new neurons in the adult songbird brain.neuron recruitment has been implicated in morphological and functional plasticity in the adult brain. whereas mammals restrict neuron recruitment specifically to two regions of known plasticity, the hippocampus and olfactory bulb, newborn neurons are found throughout the forebrain of adult songbirds. in order to study the area-specificity of the widespread proliferation and recruitment in the songbird brain, six adult male canaries received repetitive intraperitoneal injections of the mitotic ma ...201020187140
overcrowding: emergency departments are the canary in the coal mine and overcrowding is the poisonous gas. 201020195156
geographical pcb and ddt patterns in shearwaters (calonectris sp.) breeding across the ne atlantic and the mediterranean archipelagos.although seabirds have been proposed as useful biomonitors for organochlorine contaminants (ocs) in marine environments, their suitability is still unclear. to understand the geographic variability and the influence of seabird trophic ecology in oc levels, we analyzed pcbs, ddts, delta(13)c, and delta(15)n in the blood of adult calonectris shearwaters throughout a vast geographic range within the northeast atlantic ocean (from cape verde to azores) and the mediterranean sea (from the alboran sea ...201020205384
in-hospital complications and mortality following major lower extremity amputations in a series of predominantly diabetic patients.the purpose of this study was to analyze the outcomes of major lower extremity amputations (mleas) in a series, including diabetic patients, with the aim to study whether diabetes mellitus is a risk factor of in-hospital mortality and perioperative complications. a retrospective analysis of 283 mleas (221 of these patients were diabetic and 62 were nondiabetic) performed between january 1, 1998, and december 31, 2008, at the general surgery department and diabetic foot unit of la paloma hospital ...201020207619
avian bornavirus associated with fatal disease in psittacine birds.thanks to new technologies which enable rapid and unbiased screening for viral nucleic acids in clinical specimens, an impressive number of previously unknown viruses have recently been discovered. two research groups independently identified a novel negative-strand rna virus, now designated avian bornavirus (abv), in parrots with proventricular dilatation disease (pdd), a severe lymphoplasmacytic ganglioneuritis of the gastrointestinal tract of psittacine birds that is frequently accompanied by ...201020219910
bark beetles and pinhole borers (curculionidae, scolytinae, platypodinae) alien to europe.invasive bark beetles are posing a major threat to forest resources around the world. daisie's web-based and printed databases of invasive species in europe provide an incomplete and misleading picture of the alien scolytines and platypodines. we present a review of the alien bark beetle fauna of europe based on primary literature through 2009. we find that there are 18 scolytinae and one platypodinae species apparently established in europe, from 14 different genera. seventeen species are natur ...201021594183
trace element concentrations in raillietina micracantha in comparison to its definitive host, the feral pigeon columba livia in santa cruz de tenerife (canary archipelago, spain).the use of systems involving bird parasites as bioindicators of environmental pollution has been scarcely studied in comparison to other models involving fish and rodent parasites, which have been demonstrated as particularly adequate due to their bioaccumulation capacities. the present study evaluated the accumulation of nine trace elements in the cestode raillietina micracantha and in its host columba livia collected from the densely populated city of santa cruz de tenerife (canary islands, sp ...201019526264
a chemotaxonomic study of nine canarian sideritis species.nine taxa of the sideritis genus, sideritis argosphacelus var. spicata, sideritis candicans var. eriocephala,sideritis discolor, sideritis kuegleriana, sideritis lotsyi, sideritis lotsyi var. mascaensis, sideritis marmorea, sideritis soluta and sideritis tenoi, which are endemic from the canary islands, have been chemically studied. the diterpene sicanatriol 7beta,18-diacetate was obtained from s. argosphacelus var. spicata, whilst a nor-diterpene, epiadejone, and the 3(2h)-benzofuranone solutin ...200919535115
goats, birds, and emergent diseases: apparent and hidden effects of exotic species in an island environment.exotic species can have devastating effects on recipient environments and even lead to the outbreak of emergent diseases. we present here several hidden effects that the introduction of goats has had on the lesser short-toed lark, calandrella rufescens, the commonest native bird inhabiting the island of fuerteventura (canary islands). vegetation structure varied with grazing pressure, and indeed, vegetation was all but eradicated from the locality with greatest goat densities, which was also whe ...200919544728
clinicopathologic analysis of uterine sarcomas from a single institution in the canary islands.to evaluate the clinicopathologic data and prognostic factors for patients with uterine sarcomas treated at a single institution, with special emphasis on malignant mixed müllerian tumors (mmmt).200919555952
[outcome of the critical patient according to the sex and the age].to determine if gender and age are associated with differences in mortality in patients requiring critical care.200919558936
content of lead and cadmium in barred hogfish, bodianus scrofa, island grouper, mycteroperca fusca, and portuguese dogfish, centroscymnus coelolepis, from canary islands, spain.concentration of lead and cadmium has been analyzed in bodianus scrofa and mycteroperca fusca captured in the canary islands coast. concentration of pb ranged from 2.53 to 306.40 and 4.97 to 792.00 microg kg(-1) respectively, while that of cd ranged from 1.75 to 1854.50 and 6.78 to 656.00 microg kg(-1). the same metals have been analyzed in muscles, liver and skin of centroscymnus coelolepis from canary islands, with contents of pb and cd ranged between 24.18-96.12 microg kg(-1) and 32.00-3266.5 ...200919597713
epidemiology of diabetes-related lower extremity amputations in gran canaria, canary islands (spain).we have studied the rate of lower extremity amputations (leas) in the south of gran canaria. the incidence rate was 319.7 per 100,000 (95% ci, 258.6-380.8) per year in the diabetic subjects. the incidence of both diabetic and non-diabetic leas is the highest reported in spain.200919604593
impact of alien plant invaders on pollination networks in two archipelagos.mutualistic interactions between plants and animals promote integration of invasive species into native communities. in turn, the integrated invaders may alter existing patterns of mutualistic interactions. here we simultaneously map in detail effects of invaders on parameters describing the topology of both plant-pollinator (bi-modal) and plant-plant (uni-modal) networks. we focus on the invader opuntia spp., a cosmopolitan alien cactus. we compare two island systems: tenerife (canary islands) ...200919609437
susceptibility to infection and immune response in insular and continental populations of egyptian vulture: implications for conservation.a generalized decline in populations of old world avian scavengers is occurring on a global scale. the main cause of the observed crisis in continental populations of these birds should be looked for in the interaction between two factors -- changes in livestock management, including the increased use of pharmaceutical products, and disease. insular vertebrates seem to be especially susceptible to diseases induced by the arrival of exotic pathogens, a process often favored by human activities, a ...200919623256
[lifestyle, socioeconomic status and morbidity in postmenopausal women with grade ii and iii obesity].obesity has become a major public health problem in all western countries, and its prevalence is increasing. this condition is associated with a higher prevalence of diabetes mellitus, hypertension, and coronary heart disease; furthermore, obesity is a risk factor for mortality.200919627743
phylogeography and genetic structure of the canarian common chaffinch (fringilla coelebs) inferred with mtdna and microsatellite loci.the widespread common chaffinch (fringilla coelebs) inhabits five of the seven canary islands. sequences of the mitochondrial cytochrome b gene (1002bp) revealed new insights into the systematics and phylogeography of this taxon. additionally, a set of microsatellite loci were analyzed to examine the structure of these populations. our results suggest that a new species of the genus fringilla is present in the canary islands, which comprises at least three subspecies, but with a different distri ...200919632343
demographic history of canary islands male gene-pool: replacement of native lineages by european.the origin and prevalence of the prehispanic settlers of the canary islands has attracted great multidisciplinary interest. however, direct ancient dna genetic studies on indigenous and historical 17th-18th century remains, using mitochondrial dna as a female marker, have only recently been possible. in the present work, the analysis of y-chromosome polymorphisms in the same samples, has shed light on the way the european colonization affected male and female canary island indigenous genetic poo ...200919650893
measurement of key compositional parameters in two species of energy grass by fourier transform infrared spectroscopy.two energy grass species, switch grass, a north american tuft grass, and reed canary grass, a european native, are likely to be important sources of biomass in western europe for the production of biorenewable energy. matching chemical composition to conversion efficiency is a primary goal for improvement programmes and for determining the quality of biomass feed-stocks prior to use and there is a need for methods which allow cost effective characterisation of chemical composition at high rates ...200919660936
[antimicrobial susceptibility and molecular typing of enterococcus faecium isolated from humans, chickens and environment in canary islands (spain)].comparative studies on antimicrobial susceptibility patterns and molecular typing of enterococcus isolates of different origins provides valuable information concerning the epidemiology of enterococcal infections. we analyzed clinical isolates and we surveyed faecal samples of humans (hospitalised patients and healthy volunteers), faecal samples of poultry and environmental samples. a total of 68 e. faecium isolates were obtained: 43 from humans, 5 from poultry and 20 from water. we compared the ...200919662544
[assessment of nutritional quality in healthy pregnant women of the canary islands, spain].to describe the composition of the diet of healthy pregnant women of the canary islands and to estimate the nutritional quality using the healthy eating index (hei).200919679322
removal of personal care compounds from sewage sludge in reed bed container (lysimeter) studies--effects of macrophytes.sludge reed beds have been used for dewatering (draining and evapotranspiration) and mineralisation of sludge in europe since 1988. although reed beds are considered as a low cost and low contamination method in reducing volume, breaking down organic matter and increasing the density of sludge, it is not yet clear whether this enhanced biological treatment is suitable for degradation of organic micro-pollutants such as personal care products. within this project the effect of biological sludge t ...200919682727
molecular characterization of cryptosporidium spp. from fecal samples of birds kept in captivity in brazil.the aim of this study was to determine the prevalence of cryptosporidium species and genotypes in birds kept in captivity in brazil. a total of 966 samples from 18 families of birds was collected and stored in 5% potassium dichromate solution at 4 degrees c until processing. oocysts were purified in sheather sugar solution following extraction of genomic dna. molecular analyses were performed using nested-pcr for amplification of fragments of the 18s subunit of rrna gene and of the actin gene. a ...200919683397
silicosis in lymph nodes: the canary in the miner?to investigate evidence that lymph node silicosis can precede parenchymal silicosis.200919209037
foraging segregation between two closely related shearwaters breeding in sympatry.trophic segregation has been proposed as a major mechanism explaining the coexistence of closely related animal taxa. however, how such segregation varies throughout the annual cycle is poorly understood. here, we examined the feeding ecology of the two subspecies of cory's shearwater, calonectris diomedea diomedea and calonectris diomedea borealis, breeding in sympatry in a mediterranean colony. to study trophic segregation at different stages, we combined the analysis of isotope values (delta( ...200919364709
linkages between animal and human health sentinel data.in order to identify priorities for building integrated surveillance systems that effectively model and predict human risk of zoonotic diseases, there is a need for improved understanding of the practical options for linking surveillance data of animals and humans. we conducted an analysis of the literature and characterized the linkage between animal and human health data. we discuss the findings in relation to zoonotic surveillance and the linkage of human and animal data.200919389228
delta6-desaturase sequence evidence for explosive pliocene radiations within the adaptive radiation of macaronesian echium (boraginaceae).the oceanic islands of macaronesia provide an ideal temporal and spatial context to test hypotheses of plant evolution using a novel set of phylogenetic markers, delta(6)-desaturase sequences. in contrast to the limited resolution of standard molecular markers (nrdna and plastid sequences), the delta(6)-desaturase sequence phylogeny of echium unequivocally reconstructs its active colonization across islands and archipelagos (madeira, the canary islands, and cape verde), as well as its subsequent ...200919398027
history of uterine artery occlusion and subsequent pregnancy.objective: during mature placenta formation, select fetal trophoblasts invade maternal decidual arterioles and junctional zone arteries and change them into low-resistance uteroplacental arteries. consequently, physicians performing vascular procedures that occlude the uterine arteries should understand their effects on miscarriage rates, the various toxemias of pregnancy, gross and microscopic placental anatomy, and invasive placentation. thus, the objective of this article is to review the eff ...200919457823
[health services utilization by the immigrant population in spain].to compare health services utilization between the immigrant and indigenous populations in spain.200919467739
fluxes of nitrous oxide and methane on an abandoned peat extraction site: effect of reed canary grass cultivation.drained organic soils are among the most risky soil types as far as their greenhouse gas emissions are considered. reed canary grass (rcg) is a potential bioenergy crop in the boreal region, but the atmospheric impact of its cultivation is unknown. the fluxes of n(2)o and ch(4) were measured from an abandoned peat extraction site (an organic soil) cultivated with rcg using static chamber and snow gradient techniques. the fluxes were measured also at an adjacent site which is under active peat ex ...200919467859
song learning in domesticated canaries in a restricted acoustic environment.many songbirds learn their songs early in life from a song model. in the absence of such a model, they develop an improvised song that often lacks the species-typical song structure. open-ended learners, such as the domesticated canary, are able to modify their songs in adulthood, although the mechanisms that guide and time the song-learning process are still not fully understood. in a previous study, we showed that male domesticated canaries lacking an adult song model in their first year subst ...200919474048
ensifer meliloti bv. lancerottense establishes nitrogen-fixing symbiosis with lotus endemic to the canary islands and shows distinctive symbiotic genotypes and host range.eleven strains were isolated from root nodules of lotus endemic to the canary islands and they belonged to the genus ensifer, a genus never previously described as a symbiont of lotus. according to their 16s rrna and atpd gene sequences, two isolates represented minority genotypes that could belong to previously undescribed ensifer species, but most of the isolates were classified within the species ensifer meliloti. these isolates nodulated lotus lancerottensis, lotus corniculatus and lotus jap ...200919477097
[analysis of the epidemiological characteristics and prognostic factors in probable or confirmed invasive meningococcal disease in a cohort of adolescents and adults during an epidemic outbreak].to describe the profile of people suffering invasive meningococcal disease in andalusia and the canary islands, and identify the risk factors for death.200919480778
influence of social conditions in song sharing in the adult canary.in songbirds, experience of social and environmental cues during a discrete period after birth may dramatically influence song learning. in the canary, the ability to learn new songs is assumed to persist throughout life. the aim of the present study was to investigate whether social context could guide changes in adult song. three groups of canaries were kept in different social and temporal conditions. results showed that the multiple hierarchical levels of the canary song structure were affec ...200919495816
correcting for purifying selection: an improved human mitochondrial molecular clock.there is currently no calibration available for the whole human mtdna genome, incorporating both coding and control regions. furthermore, as several authors have pointed out recently, linear molecular clocks that incorporate selectable characters are in any case problematic. we here confirm a modest effect of purifying selection on the mtdna coding region and propose an improved molecular clock for dating human mtdna, based on a worldwide phylogeny of > 2000 complete mtdna genomes and calibratin ...200919500773
bdnf increases brdu-ir cells in the injured adult zebra finch hippocampus.steroid-mediated cell proliferation, differentiation, and survival can be triggered by learning, experience, and brain injury. in the uninjured canary song system, testosterone induces cell proliferation that is blocked by an antibody to brain-derived neurotrophic factor (bdnf). however, little is known with regard to the effects of neurotrophic factors on injury-induced cell proliferation and incorporation. to address this, adult male zebra finches received bilateral hippocampal lesions by infu ...200919512953
low-dimensional dynamical model for the diversity of pressure patterns used in canary song.during song production, oscine birds produce large air sac pressure pulses. during those pulses, energy is transferred to labia located at the juncture between the bronchii and the trachea, inducing the high frequency labial oscillations which are responsible for airflow modulations, i.e., the uttered sound. in order to generate diverse syllables, canaries (serinus canaria) use a set of air sac pressure patterns with characteristic shapes. in this work we show that these different shapes can be ...200919518278
a new anoplocephalid (cestoda: cyclophyllidea) from gallotia atlantica (reptilia, lacertidae) in the canary islands, spain.a new species of anoplocephalid cestode is described from gallotia atlantica (reptilia, lacertidae) on the canary islands, spain. oochoristica feliui n. sp. belongs to the group of oochoristica spp. having circular suckers and fewer than 25 testes in a single cluster: o. lygosomae burt, 1933; o. lygosomatis skinker, 1935; o. elongata dupouy et kechemir, 1973; o. jonnesi bursey, mcallister and freed, 1997; o. junkea johri, 1950; o. macallisteri bursey and goldberg, 1996; o. novaezelandae schmidt ...200919090647
no "canary in the coalmine" for intra-abdominal hypertension. 200919112315
genetic diversity and differentiation processes in the ploidy series of olea europaea l.: a multiscale approach from subspecies to insular populations.geographical isolation and polyploidization are central concepts in plant evolution. the hierarchical organization of archipelagos in this study provides a framework for testing the evolutionary consequences for polyploid taxa and populations occurring in isolation. using amplified fragment length polymorphism and simple sequence repeat markers, we determined the genetic diversity and differentiation patterns at three levels of geographical isolation in olea europaea: mainland-archipelagos, isla ...200919143937
withanolides from whitania aristata and their diuretic activity.withania aristata is an endemic plant used traditionally in canary islands as a diuretic. in this paper, we report on this pharmacological activity in several extracts of the dry vegetal material collected and the identification and diuretic activity of two withanolides, one of them previously not reported, isolated from the most active fraction.200919146940
repertoire sharing and auditory responses in the hvc of the canary.in songbirds, auditory neurons of the nucleus hvc respond selectively to a particular complex sound, the bird's own song (bos). in the canary, this song selectivity did not exclude responses to conspecific songs. here, we recorded single units in nucleus hvc of adult canaries to assess to what extent repertoire sharing among birds contributed to auditory responsiveness to birds' songs other than the bos. results indicated that song phrases driving auditory responses could differ from bird's own ...200919151601
the ggn and cag repeat polymorphisms in the exon-1 of the androgen receptor gene are, respectively, associated with insulin resistance in men and with dyslipidemia in women.the human androgen receptor (ar) gene possesses two trinucleotide repeats of cag and ggn in exon-1. the ggn repeat affects the amount of ar protein translated, while the cag repeat affects the efficiency of ar transcriptionaly. in this study, we have genotyped these polymorphic tracts in a representative sample of 557 caucasian adult individuals (314 women and 243 men) from the canary islands, spain (the enca study), and investigated their association with fasting serum levels of lipids, glucose ...200919159685
caboxamycin, a new antibiotic of the benzoxazole family produced by the deep-sea strain streptomyces sp. ntk 937.caboxamycin, a new benzoxazole antibiotic, was detected by hplc-diode array screening in extracts of the marine strain streptomyces sp. ntk 937, which was isolated from deep-sea sediment collected in the canary basin. the structure of caboxamycin was determined by mass spectrometry, nmr experiments and x-ray analysis. it showed inhibitory activity against gram-positive bacteria, selected human tumor cell lines and the enzyme phosphodiesterase.200919198633
fog reduces transpiration in tree species of the canarian relict heath-laurel cloud forest (garajonay national park, spain).the ecophysiologic role of fog in the evergreen heath-laurel 'laurisilva' cloud forests of the canary islands has not been unequivocally demonstrated, although it is generally assumed that fog water is important for the survival and the distribution of this relict paleoecosystem of the north atlantic macaronesian archipelagos. to determine the role of fog in this ecosystem, we combined direct transpiration measurements of heath-laurel tree species, obtained with granier's heat dissipation probes ...200919203969
ultrastructural study of the spermatozoon of taenia taeniaeformis (batsch, 1786) (cestoda, cyclophyllidea, taeniidae), an intestinal parasite of felis catus from la palma (canary islands, spain).the ultrastructural characters of the mature spermatozoon of taenia taeniaeformis are described by means of transmission electron microscopy. materials were obtained from a naturally infected road-killed cat (felis catus) from la palma (canary islands, spain). the mature spermatozoon of t. taeniaeformis is a filiform cell, which is tapered at both extremities and lacks mitochondria. it is characterised by the presence of (1) a single spirallised crested body about 140 nm thick, (2) a single axon ...200919205741
[epidemiological features of invasive pneumococcal disease before and after the introduction of pneumococcal conjugate vaccine in gran canaria (canary islands)].the introduction of pneumococcal conjugate vaccine (pcv-7) has modified the epidemiology of invasive pneumococcal disease (ipd). our aim was to investigate the epidemiological features of ipd before and after implementing the use of pcv-7.200919217998
rhizobia from lanzarote, the canary islands, that nodulate phaseolus vulgaris have characteristics in common with sinorhizobium meliloti isolates from mainland spain.the stable, low-molecular-weight (lmw) rna fractions of several rhizobial isolates of phaseolus vulgaris grown in the soil of lanzarote, an island of the canary islands, were identical to a less-common pattern found within sinorhizobium meliloti (assigned to group ii) obtained from nodules of alfalfa and alfalfa-related legumes grown in northern spain. the p. vulgaris isolates and the group ii lmw rna s. meliloti isolates also were distinguishable in that both had two conserved inserts of 20 and ...200919218416
kleemeier award lecture 2008--the canary in the coal mine: telomeres and human healthspan.telomeres, the repeated series of dna sequences that cap the ends of linear chromosomes, become shorter during cell division and oxidative stress. shortened telomeres have been documented in a wide variety of pathologies associated with aging and are also predictive of early mortality in the very old. however, telomere shortening--like the canary in the coal mine--is not the cause of the deleterious effects, but rather, the harbinger of increased health risk. using immune responses to infection ...200919228779
[regional differences between glomerulonephritis in the canary islands]. 200919240780
[framingham function estimates the risk of cardio vascular mortality more effectively than score function in the population of the canary islands (spain)].to compare the performance of the framingham and score functions to estimate fatal cardiovascular events. in addition, we explored the ability of both functions to detect the risk contributed by factors not included in their equations: sedentariness, obesity, abdominal circumference, abdomen/height razón, abdomen/pelvis ratio, and excessive alcohol consumption.200919250709
[review of the protocol for the treatment of diabetic retinopathy].we present general guidelines to help us with the treatment of diabetic retinopathy (dr) at a time when numerous therapeutic alternatives have been developed although their role has not yet been adequately defined. this protocol is not directed at experienced retinologists but rather at general ophthalmologists who require a practical and up to date guide of a pathology as prevalent as rd. the different therapeutic options available, and their most accepted indications depending on the degree of ...200919253176
biogas production from boreal herbaceous grasses--specific methane yield and methane yield per hectare.the objective of this study was to determine the specific methane yields of four grass species (cocksfoot, tall fescue, reed canary grass and timothy) cultivated under boreal conditions as well as how harvesting time and year of cultivation affects the specific methane yields per ha. the specific methane yields of all grasses and all harvests varied from 253 to 394 nl ch4/kg volatile solids (vs) added. the average specific methane yield of the 1st harvest of all grasses was higher than the 2nd h ...200919261471
involvement of phytosulfokine in the attenuation of stress response during the transdifferentiation of zinnia mesophyll cells into tracheary elements.phytosulfokine (psk) is a sulfated peptide hormone required for the proliferation and differentiation of plant cells. here, we characterize the physiological roles of psk in transdifferentiation of isolated mesophyll cells of zinnia (zinnia elegans 'canary bird') into tracheary elements (tes). transcripts for a zinnia psk precursor gene, zepsk1, show two peaks of expression during te differentiation; the first accumulation is transiently induced in response to wounding at 24 h of culture, and th ...200919270060
a global assessment of chromium pollution using sperm whales (physeter macrocephalus) as an indicator species.chromium (cr) is a well-known human carcinogen and a potential reproductive toxicant, but its contribution to ocean pollution is poorly understood. the aim of this study was to provide a global baseline for cr as a marine pollutant using the sperm whale (physeter macrocephalus) as an indicator species. biopsies were collected from free-ranging whales around the globe during the voyage of the research vessel the odyssey. total cr levels were measured in 361 sperm whales collected from 16 regions ...200919324391
respiratory fluxes in a canary islands pine forest.we estimated component and whole-ecosystem co(2) efflux (r(eco)) in a pinus canariensis chr. sm. ex dc stand in tenerife, canary islands, an ecotone with strong seasonal changes in soil water availability. from november 2006 to february 2008, we measured foliage, stem and soil co(2) efflux by chamber techniques. site-specific co(2) efflux models obtained from these chamber measurements were then combined with half-hourly measurements of canopy, stem and soil temperature as well as soil water pot ...200919324703
the world's first immunization campaign: the spanish smallpox vaccine expedition, 1803-1813.summary: smallpox produced the death of up to thirty percent of those infected, so jenner's preventive method spread quickly. the spanish government designed and supported a ten-year effort to carry smallpox vaccine to its american and asian territories in a chain of arm-to-arm vaccination of children. an expedition directed by doctor francisco xavier de balmis sailed from corunna in november 1803, stopping in the canary islands, puerto rico, and venezuela. balmis led a subexpedition to cuba, me ...200919329842
the economic costs and health-related quality of life of people with hiv/aids in the canary islands, spain.the objective was to determine the economic burden, as well as the impact on hrqol for people with hiv/aids in spain in 2003.200919331682
the maternal aborigine colonization of la palma (canary islands).teeth from 38 aboriginal remains of la palma (canary islands) were analyzed for external and endogenous mitochondrial dna control region sequences and for diagnostic coding positions. informative sequences were obtained from 30 individuals (78.9%). the majority of lineages (93%) were from west eurasian origin, being the rest (7%) from sub-saharan african ascription. the bulk of the aboriginal haplotypes had exact matches in north africa (70%). however, the indigenous canarian sub-type u6b1, also ...200919337312
pre-hospital antibiotic treatment and mortality caused by invasive meningococcal disease, adjusting for indication bias.mortality from invasive meningococcal disease (imd) has remained stable over the last thirty years and it is unclear whether pre-hospital antibiotherapy actually produces a decrease in this mortality. our aim was to examine whether pre-hospital oral antibiotherapy reduces mortality from imd, adjusting for indication bias.200919344518
detection of myocardial dysfunction during cancer chemotherapy with tissue doppler imaging: a canary in the coal mine? 200919345310
willingness to undergo colorectal cancer screening in first-degree relatives of hospitalized patients with colorectal cancer.to evaluate whether willingness to undergo colonoscopy screening is influenced by being a first-degree relative of hospitalized patients with or without colorectal cancer after briefing and surgeon recommendation.200919349529
poverty is a risk factor for osteoporotic fractures.this study assesses the possible association between poverty and osteoporosis and/or fragility fractures in a population of postmenopausal women. we found that postmenopausal women with low socioeconomic status had lower values of bmd at the lumbar spine, a higher prevalence of densitometric osteoporosis, and a higher prevalence of total and vertebral fractures.200918773136
fungal diversity in the rhizosphere of endemic plant species of tenerife (canary islands): relationship to vegetation zones and environmental factors.knowledge about fungal diversity scaling relationships relative to that of plants is important to understand ecosystem functioning. tenerife island, a natural laboratory to study terrestrial biodiversity, is represented by six different vegetation zones characterized by specific abiotic conditions and plant communities with a high proportion of endemic plants. little is known about the biodiversity of associated fungi. to understand the relationship between plant and fungal communities, we analy ...200918830279
avian mycobacteriosis in companion birds: 20-year survey.the causative agents of avian mycobacteriosis in pet birds are rarely identified. the aim of this study is to add information about the etiology of avian mycobacteriosis. the identification of mycobacterium species in 27 cases of avian mycobacteriosis in pet birds was investigated by polymerase chain reaction (pcr) and sequencing of a rrna hypervariable region. avian mycobacteriosis appeared to be an infrequent diagnosis. interestingly, a few cases of avian mycobacteriosis were recorded in very ...200918789612
bird pollination of canary island endemic plants.the canary islands are home to a guild of endemic, threatened bird-pollinated plants. previous work has suggested that these plants evolved floral traits as adaptations to pollination by flower specialist sunbirds, but subsequently, they appear to have co-opted generalist passerine birds as sub-optimal pollinators. to test this idea, we carried out a quantitative study of the pollination biology of three of the bird-pollinated plants, canarina canariensis (campanulaceae), isoplexis canariensis ( ...200918931830
negative per capita effects of two invasive plants, lythrum salicaria and phalaris arundinacea, on the moth diversity of wetland communities.invasive plants have been shown to negatively affect the diversity of plant communities. however, little is known about the effect of invasive plants on the diversity at other trophic levels. in this study, we examine the per capita effects of two invasive plants, purple loosestrife (lythrum salicaria) and reed canary grass (phalaris arundinacea), on moth diversity in wetland communities at 20 sites in the pacific northwest, usa. prior studies document that increasing abundance of these two plan ...200918947450
evaluating new candidate snps as low penetrance risk factors in sporadic breast cancer: a two-stage spanish case-control study.a polygenic model has been proposed in order to explain the genetic susceptibility to sporadic breast cancer. according to this model, common population variants would be responsible for low to modest effects on the risk of developing the disease. we have carried out a high-throughput snp genotyping project in order to shed some light on the complex genetic aetiology of non-familial breast cancer.200918950845
long-term effects of lead poisoning on bone mineralization in vultures exposed to ammunition sources.long-lived species are particularly susceptible to bioaccumulation of lead in bone tissues. in this paper we gain insights into the sublethal effects of lead contamination on egyptian vultures (neophron percnopterus). our approach was done on the comparison of two populations (canary islands and iberian peninsula) differing in exposures to the ingestion of lead ammunition. blood lead levels were higher in the island population (canary islands range: 5.10-1780 microg l(-1) n=137; iberian peninsul ...200918995938
photosynthesis, chloroplast pigments, and antioxidants in pinus canariensis under free-air ozone fumigation.high o3 levels, driving uptake and challenging defense, prevail on the canary islands, being associated with the hot and dry summers of the mediterranean-type climate. pinus canariensis is an endemic conifer species that forms forests across these islands. we investigated the effects of ozone on photosynthesis and biochemical parameters of p. canariensis seedlings exposed to free-air o3 fumigation at kranzberg forest, germany, where ambient o3 levels were similar to those at forest sites in the ...200919000645
therapy in a subtropical climate for children with cerebral palsy. evidence of physical and psychosocial effects?to assess a possible therapeutic effect in children and adolescents with cerebral palsy of a habilitation programme in a warm sunny climate.200919006523
molecular markers reveal no genetic differentiation between myrica rivas-martinezii and m. faya (myricaceae).myrica rivas-martinezii is a critically endangered endemic of the laurel forest of the canary islands and co-occurs very close to m. faya. some authors suggest that m. rivas-martinezii and m. faya are two morphs of the same species, so molecular markers were used to estimate the levels and structuring of genetic variation within and among natural populations in order to evaluate genetic relationships between these two congeners.200919008254
hypericum grandifolium choisy: a species native to macaronesian region with antidepressant effect.various species of hypericum genus have been used in the canary islands as sedative, diuretic, vermifuge, wound healing, antihysteric and antidepressant agent. studies have shown that methanol extract of hypericum grandifolium choisy is active in tetrabenazine-induced ptosis and forced swimming tests. in the current study, the aqueous, butanol and chloroform fractions obtained from the methanol extract as well as three sub-fractions derived from the chloroform fraction were evaluated for their c ...200919041704
the peopling of madeira archipelago (portugal) according to hla genes.the madeira-porto santo archipelago was officially colonized in 1420 by portuguese settlers. its importance in columbus' information for the american discovery and for slave traffic across the atlantic is unquestionable. thus, a complex peopling may have given rise to a present-day high admixture of ethnicities according to hla genes. a sample of 173 healthy unrelated madeirans was analysed and compared with 6986 hla chromosomes from other worldwide populations. genetic distances, neighbour-join ...200919055604
maternal effects and beta-carotene assimilation in canary chicks.carotenoids are pigments responsible for the red, orange and yellow coloration of plants and animals. they may be beneficial in two ways; they have a powerful antioxidant activity, and they can behave as an immunostimulant. animals however cannot synthesize carotenoids de novo, they must obtain them through their diet. in our experiments on canaries, we investigated how mothers transfer their dietary carotenoid-related benefits to their offspring; either through the egg, or through the diet (dur ...200919059274
high levels of polychlorinated biphenyls in tissues of atlantic turtles stranded in the canary islands, spain.polychlorinated biphenyls (pcbs 28, 31, 52, 101, 138, 153, 180, and 209) were measured in tissue samples (liver and fat) from 30 loggerhead turtles caretta caretta, 1 green turtle chelonia mydas, and 1 leatherback dermochelys coriacea stranded on the coasts of the canary islands, trying to establish a possible relation between pcb concentrations and the lesions and causes of death. tissues from these turtles contained higher levels of pcbs than those reported in turtles from other geographical r ...200919062067
obesity and health related quality of life in the general adult population of the canary islands.to explore the relationship between excess weight and health related quality of life (hrql) in the general population by means of the euroqol-5d questionnaire.200919067234
local adaptation of stress related traits in drosophila buzzatii and drosophila simulans in spite of high gene flow.we addressed the question if local adaptation to a thermal gradient is possible in spite of a high gene flow among closely spaced populations of two species of drosophila from the island of la gomera (canary islands). variation in multiple traits related to stress resistance in different life stages was measured in both species in flies collected from five localities at different altitudes and thereby with different climatic conditions. based on microsatellite loci, the populations were not gene ...200921462416
characterization of six microsatellite loci in myrica faya (myricaceae) and cross amplification in the endangered endemic m. rivas-martinezii in canary islands, spain.six novel polymorphic microsatellite markers were isolated from enriched libraries in myrica faya ait., recently renamed morella faya, (fayatree, firetree, or firebush) in order to examine the genetic diversity in natural populations. also, test cross-specific amplification and genetic diversity in myrica rivas-martinezii, which is endemic on the canary islands. microsatellite loci were screened in 225 individuals of both species from different islands of the canarian archipelago. all markers we ...200921637655
ionic liquid based dispersive liquid-liquid microextraction for the extraction of pesticides from bananas.this paper describes a dispersive liquid-liquid microextraction (dllme) procedure using room temperature ionic liquids (rtils) coupled to high-performance liquid chromatography with diode array detection capable of quantifying trace amounts of eight pesticides (i.e. thiophanate-methyl, carbofuran, carbaryl, tebuconazole, iprodione, oxyfluorfen, hexythiazox and fenazaquin) in bananas. fruit samples were first homogenized and extracted (1g) with acetonitrile and after suitable evaporation and reco ...200919700165
novel avian bornavirus in a nonpsittacine species (canary; serinus canaria) with enteric ganglioneuritis and encephalitis.a canary bird (serinus canaria) died with nonsuppurative ganglioneuritis of the proventriculus and gizzard and encephalitis, lesions comparable to proventricular dilatation disease (pdd) of psittacine birds. recently, several genotypes of a novel avian bornavirus have been linked to pdd. in the canary, bornaviral antigen was detected by immunohistochemistry in both neural and extraneural tissues. the widespread viral dissemination was confirmed by reverse transcription-pcr. sequence analysis rev ...200919706702
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