Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [intestinal parasitism in terena indigenous people of the province of mato grosso do sul, brazil]. | considering that intestinal protozoans and helminths infect more than half of the world population, with high prevalence in the poorest regions, the objective of this study was to conduct parasitological research among indigenous terena people established in the state of matogrosso do sul. an inquiry was performed to find the incidence of parasitism in these communities. | 2015 | 26120856 |
| predicting frequency distribution and influence of sociodemographic and behavioral risk factors of schistosoma mansoni infection and analysis of co-infection with intestinal parasites. | geospatial analysis was used to study the epidemiology of schistosoma mansoni, intestinal parasites and co-infections in an area (ilha das flores) in sergipe, brazil. we collected individually georeferenced sociodemographic, behavioral and parasitological data from 500 subjects, analyzed them by conventional statistics, and produced risk maps by kernel estimation. the prevalence rates found were: s. mansoni (24.0%), trichuris trichiura (54.8%), ascaris lumbricoides (49.2%), hookworm (17.6%) and ... | 2015 | 26054512 |
| dramatic decrease in prevalence of soil-transmitted helminths and new insights into intestinal protozoa in children living in the chaco region, bolivia. | we assessed the prevalence of intestinal parasites among 268 2-12-year-old children living in rural areas, small villages, and semi-urban areas of the chaco region, south-eastern bolivia. the overall parasitism was 69%. only protozoa, helminths, or co-infections were observed in 89.2%, 5.9%, or 4.9% of the positive children, respectively. a significant progressive increase in overall parasite prevalence was found when passing from rural areas to small villages and semi-urban areas. the most comm ... | 2015 | 25711609 |
| cellular cytokine and chemokine responses to parasite antigens and fungus and mite allergens in children co-infected with helminthes and protozoa parasites. | in sub-saharan africa poly-parasite infections are frequently observed in children, and with poly-parasitism modulating immune mechanisms, mediated by cytokines and chemokines, are required to prevent overwhelming inflammation and host tissue damage. we analyzed in children co-infected with helminthes and protozoan parasites their cellular production of regulatory and pro-inflammatory cytokines and chemokines in response to parasite antigens and allergens. | 2015 | 25698903 |
| intestinal parasitic infections among mentally handicapped individuals in alexandria, egypt. | this cross-sectional study was carried to determine the prevalence of intestinal parasitic infections among mentally handicapped individuals in alexandria, egypt, in the period from december 2012 till november 2013. the study was conducted on 200 institutionalized and non-institutionalized mentally handicapped individuals. fresh stool samples were subjected to different stains including; trichrome for detecting intestinal protozoa, modified acid fast stain for intestinal coccidia and quick hot g ... | 2015 | 26878626 |
| intestinal parasites detected during pre-employment stool examination at tertiary health care center in makkah, kingdom of saudi arabia. | this retrospective study determined the intestinal parasites discovered in 2490 new employees in a tertiary health care center in makah as regards nationalities, age groups and sex over the period from january 2010 to january 2014 to decrease introduction of communicable diseases. all the data were provided through the electronic hospital information system. the overall positive cases were 16%, significantly higher in females 57.4% than males 42.6%. differences in distribution of positive record ... | 2015 | 26485855 |
| simultaneous detection of entamoeba histolytica/dispar, giardia duodenalis and cryptosporidia by immunochromatographic assay in stool samples from patients living in the greater cairo region, egypt. | gastrointestinal infection due to intestinal parasites is an enormous health problem in developing countries and its reliable diagnosis is demanding. therefore, this study aimed at evaluating a commercially available immunochromatographic assay (ica) for the detection of cryptosporidia, giardia duodenalis, and entamoeba histolytica/dispar for its usefulness in the greater cairo region, egypt. stool samples of 104 patients who presented between october 2012 and march 2013 with gastrointestinal sy ... | 2015 | 26018117 |
| intestinal parasitic infection among egyptian children with chronic liver diseases. | patients with chronic liver diseases (cld) are often highly susceptible to parasitic infection due to a depressed immune system. the objective of this study was to detect the most commonly intestinal parasites found among egyptian children with cld. the present study was conducted on 50 children with cld of different etiology (25 were having different intestinal symptoms, 25 without intestinal symptoms) and 50 non-cld children with gastrointestinal complaints served as controls. all cases were s ... | 2015 | 25698851 |
| intestinal parasitic infections and anaemia among pregnant women in the highlands of papua new guinea. | this study determined the prevalence of intestinal parasitic infections and associations with risk factors among pregnant women in their second or third trimester in goroka, eastern highlands province, papua new guinea. among the 201 pregnant women enrolled in this study, 163 (81%) were infected with one or more intestinal parasites. infections with protozoan parasites (65%) were more prevalent than infections with nematodes (31%); protozoan infections included entamoeba histolytica (43%), giard ... | 2015 | 26288929 |
| diversity and prevalence of gastrointestinal parasites in seven non-human primates of the taï national park, côte d'ivoire. | parasites and infectious diseases are well-known threats to primate populations. the main objective of this study was to provide baseline data on fecal parasites in the cercopithecid monkeys inhabiting côte d'ivoire's taï national park. seven of eight cercopithecid species present in the park were sampled: cercopithecus diana, cercopithecus campbelli, cercopithecus petaurista, procolobus badius, procolobus verus, colobus polykomos, and cercocebus atys. we collected 3142 monkey stool samples betw ... | 2015 | 25619957 |
| in vitro studies of chromone-tetrazoles against pathogenic protozoa, bacteria, and fungi. | in vitro studies to fourteen previously synthesized chromone-tetrazoles and four novel fluorine-containing analogs were conducted against pathogenic protozoan (entamoeba histolytica), pathogenic bacteria (pseudomonas aeruginosa, and staphylococcus aureus), and human fungal pathogens (sporothrix schenckii, candida albicans, and candida tropicalis), which have become in a serious health problem, mainly in tropical countries. | 2015 | 26184131 |
| amoebiasis masquerading as inflammatory bowel disease. | a 60-year-old japanese man presented with bloody diarrhoea. he stated that he had been diagnosed with ulcerative colitis (uc) 3 years prior, but discontinued follow-up care as treatment was ineffective. one year later, he came to our hospital with anorexia and weight loss. the abdomen was soft and flat without tenderness. laboratory tests were unremarkable; faecal culture and clostridium difficile toxin were negative. findings and biopsy from a subsequent colonoscopy reconfirmed his diagnosis of ... | 2015 | 26607188 |
| metronidazole-triazole conjugates: activity against clostridium difficile and parasites. | metronidazole has been used clinically for over 50 years as an antiparasitic and broad-spectrum antibacterial agent effective against anaerobic bacteria. however resistance to metronidazole in parasites and bacteria has been reported, and improved second-generation metronidazole analogues are needed. the copper catalysed huigsen azide-alkyne 1,3-dipolar cycloaddition offers a way to efficiently assemble new libraries of metronidazole analogues. several new metronidazole-triazole conjugates (mtz- ... | 2015 | 26117821 |
| dbdiasnp: an open-source knowledgebase of genetic polymorphisms and resistance genes related to diarrheal pathogens. | diarrhea is a highly common infection among children, responsible for significant morbidity and mortality rate worldwide. after pneumonia, diarrhea remains the second leading cause of neonatal deaths. numerous viral, bacterial, and parasitic enteric pathogens are associated with diarrhea. with increasing antibiotic resistance among enteric pathogens, there is an urgent need for global surveillance of the mutations and resistance genes primarily responsible for resistance to antibiotic treatment. ... | 2015 | 25978092 |
| [the application and epidemiological research of xtag gpp multiplex pcr in the diagnosis of infectious diarrhea]. | to investigate the application value of xtag (®) gastrointestinal pathogen panel (xtag9(®) gpp) multiplex pcr in the early diagnosis of infectious diarrhea, and understand the epidemiology of intestinal diarrhea pathogens. | 2015 | 25916780 |
| spectrum of enteropathogens detected by the filmarray gi panel in a multicentre study of community-acquired gastroenteritis. | the european, multicentre, quarterly point-prevalence study of community-acquired diarrhoea (eucodi) analysed stool samples received at ten participating clinical microbiology laboratories (austria, finland, france, germany, greece, ireland, italy, portugal, romania, and the uk) in 2014. on four specified days, each local laboratory submitted samples from ≤20 consecutive patients to the austrian study centre for further testing with the filmarray gi panel (biofire diagnostics, salt lake city, ut ... | 2015 | 25908431 |
| dead/dexh-box rna helicases in selected human parasites. | dead/dexh-box rna helicases catalyze the folding and remodeling of rna molecules in prokaryotic and eukaryotic cells, as well as in many viruses. they are characterized by the presence of the helicase domain with conserved motifs that are essential for atp binding and hydrolysis, rna interaction, and unwinding activities. large families of dead/dexh-box proteins have been described in different organisms, and their role in all molecular processes involving rna, from transcriptional regulation to ... | 2015 | 26537038 |
| antiparasitic activity of silver and copper oxide nanoparticles against entamoeba histolytica and cryptosporidium parvum cysts. | nanoparticles (nps) have received more attention as antiparasitic agents. in the present study, silver and copper nanoparticles were synthesized and characterized using scanning electron microscopy (sem), transmission electron microscope (tem) and x-ray fluorescence (xrf). the antiparasitic activity of ag and cuo nanoparticles were tested against two of the most environmentally spread parasites in egypt (entamoeba histolytica and cryptosporidium parvum). the average sizes of synthesized ag nps a ... | 2015 | 26939237 |
| intestinal parasites in diabetic patients in sohag university hospitals, egypt. | intestinal parasites usually create benign diseases, though they may induce complications with high morbidity and mortality to the immunocompromised, including diabetic patients. the study detected the prevalence of intestinal parasitic infections in diabetic patients, comparing to non-diabetic controls and other parameters. a total of 100 fecal samples were collected from diabetic patients at the outpatient clinic of sohag university hospitals and another 100 from cross matched controls. the sa ... | 2015 | 26485865 |
| prevalence of cryptosporidium parvum/hominis, entamoeba histolytica and giardia lamblia among young children with and without diarrhea in dar es salaam, tanzania. | although enteroparasites are common causes of diarrheal illness, few studies have been performed among children in tanzania. this study aimed to investigate the prevalence of cryptosporidium parvum/hominis, entamoeba histolytica and giardia lamblia among young children in dar es salaam, tanzania, and identify risk factors for infection. | 2015 | 26452235 |
| burden of major diarrheagenic protozoan parasitic co-infection among amoebic dysentery cases from north east india: a case report. | intestinal diarrheagenic polyparasitic infections are among the major public health concerns in developing countries. here we examined stool specimens by microscopy, dna dot blot and polymerase chain reaction (pcr) to evaluate the co-infection of four principal protozoans among amoebic dysentery cases from northeast indian population. the multiplex pcr confirmed entamoeba histolytica (8.1%), entamoeba dispar (4.8%) and mixed infection of both the parasites (3.4%) in 68 of 356 stool specimens tha ... | 2015 | 26099490 |
| [evaluation of the new immunocard stat!® cge test for the diagnosis of amebiasis]. | for many years, microscopic examination of stool samples has been considered to be the "gold standard" for diagnosis of intestinal parasites although the polymerase chain reaction (pcr) analysis is increasingly utilized due to its high accuracy. recently, pcr has been approved by the world health organization as the current method of choice for the diagnosis of entamoeba histolytica infection. in this study we evaluated a novel immunochromatographic antigen detection rapid test, immunocardstat c ... | 2015 | 26018388 |
| improved orthologous databases to ease protozoan targets inference. | homology inference helps on identifying similarities, as well as differences among organisms, which provides a better insight on how closely related one might be to another. in addition, comparative genomics pipelines are widely adopted tools designed using different bioinformatics applications and algorithms. in this article, we propose a methodology to build improved orthologous databases with the potential to aid on protozoan target identification, one of the many tasks which benefit from com ... | 2015 | 26416523 |
| increasing anaerobic acetate consumption and ethanol yields in saccharomyces cerevisiae with nadph-specific alcohol dehydrogenase. | saccharomyces cerevisiae has recently been engineered to use acetate, a primary inhibitor in lignocellulosic hydrolysates, as a cosubstrate during anaerobic ethanolic fermentation. however, the original metabolic pathway devised to convert acetate to ethanol uses nadh-specific acetylating acetaldehyde dehydrogenase and alcohol dehydrogenase and quickly becomes constrained by limited nadh availability, even when glycerol formation is abolished. we present alcohol dehydrogenase as a novel target f ... | 2015 | 26386051 |
| [intestinal parasitosis among non-permanent resident students in tunisia: a review of 23 years of monitoring in the department of parasitology-mycology at the rabta hospital of tunisia]. | in order to fight digestive parasitism in tunisia, a national program of surveillance of non-permanent resident students in tunisia has been found to detect these parasitosis in this target population. | 2015 | 26757499 |
| evolution of the prevalence of intestinal parasitosis in the region of tunis from 1996 at 2012. | the prevalence of intestinal parasitosis is very different according to countries. therefore, it is always interesting to update the data in tunisia to better direct control measures. | 2015 | 27126425 |
| prevalence of intestinal opportunistic parasites infections in the university hospital of bobo-dioulasso, burkina faso. | gastrointestinal parasites infections are widespread in africa and their prevalence infections vary from country to country. this study aimed at assessing the prevalence of opportunistic intestinal parasites infection and other gastrointestinal parasites infection among patients attending the laboratory of parasitology and mycology of the university hospital souro sanou of bobo-dioulasso. | 2015 | 26217488 |
| prevalence of intestinal protozoan infections among individuals living with hiv/aids at felegehiwot referral hospital, bahir dar, ethiopia. | hiv infection continues to pose a serious challenge to global health by predisposing patients to opportunistic infections. a cross-sectional study was conducted from december 2012 to february 2013 to assess the enteric protozoan infection status among individuals living with hiv/aids in felegehiwot referral hospital, bahir dar, northwest ethiopia. | 2015 | 25917962 |
| prevalence of intestinal protozoa among saudi patients with chronic renal failure: a case-control study. | it has been hypothesized that chronic renal failure (crf) predisposes patients to infection with intestinal protozoa. we tested this hypothesis with a matched case-control study to determine the prevalence of these protozoa and their diarrhea associated symptoms among 50 patients with crf (cases) from taif, western saudi arabia. fifty diarrheal patients without crf were recruited in the study as controls. participants were interviewed by a structured questionnaire and stool samples were collecte ... | 2015 | 26491455 |
| [environmental conditions and prevalence of parasitic infection in xukuru-kariri indigenous people, caldas, brazil]. | to describe the environmental conditions and the parasitic infection status of xukuru-kariri individuals living in the municipality of caldas, state of minas gerais, brazil. | 2015 | 26506320 |
| intestinal parasites in patients with chronic abdominal pain. | information about intestinal parasites in sohag (upper egypt) in patients with chronic abdominal pain is scarce. this study determined the intestinal parasites symptoms in 130 patients with chronic abdominal pain and cross-matched 20 healthy persons. parasitic infection was confirmed by stool analysis.the most commonest clinical data with stool analysis was as following: 1-entamoeba histolytica associated with nausea 20 (3 7.74%) followed by anorexia 19 (35.85%), 2-entamoeba coli associated with ... | 2015 | 26485858 |
| evaluation of factors affecting real-time pcr performance for diagnosis of entamoeba histolytica and entamoeba dispar in clinical stool samples. | although pcr offers the potential for sensitive detection of parasites there are several pitfalls for optimal performance, especially when dna is extracted from a complex sample material such as stool. with the aid of a sensitive inhibitor control in a duplex real-time pcr (qpcr) for identification of entamoeba histolytica and entamoeba dispar we have evaluated factors that influenced the performance of the qpcr and have suggested a rationale to be used in the analysis of clinical samples. pre-p ... | 2015 | 26296348 |
| cell-matrix interactions of entamoeba histolytica and e. dispar. a comparative study by electron-, atomic force- and confocal microscopy. | invasion of tissues by entamoeba histolytica is a multistep process that initiates with the adhesion of the parasite to target tissues. the recognition of the non-invasive entamoeba dispar as a distinct, but closely related protozoan species raised the question as to whether the lack of its pathogenic potential could be related to a weaker adhesion due to limited cytoskeleton restructuring capacity. we here compared the adhesion process of both amebas to fibronectin through scanning, transmissio ... | 2015 | 26231438 |
| intestinal amebae. | among the entamoeba species that infect humans, entamoeba histolytica causes diseases, entamoeba dispar is a harmless commensal, entamoeba moshkovskii seems to be a pathogen, and the pathogenicity of entamoeba bangladeshi remains to be investigated. species-specific detection needed for treatment decisions and for understanding the epidemiology and pathogenicity of these amebae. antigen-based detection methods are needed for e dispar, e moshkovskii, and e bangladeshi; and molecular diagnostic te ... | 2015 | 26004649 |
| maldi-tof mass spectrometry for the detection and differentiation of entamoeba histolytica and entamoeba dispar. | detection of entamoeba histolytica and its differentiation from entamoeba dispar is an important goal of the clinical parasitology laboratory. the aim of this study was the identification and differentiation of e. histolytica and e. dispar by maldi-tof ms, in order to evaluate the application of this technique in routine diagnostic practice. maldi-tof ms was applied to 3 amebic reference strains and to 14 strains isolated from feces that had been differentiated by molecular methods in our labora ... | 2015 | 25874612 |
| bioconjugated fluorescent silica nanoparticles for the rapid detection of entamoeba histolytica. | rapid detection of entamoeba histolytica based on fluorescent silica nanoparticle (fsnp) indirect immunofluorescence microscopy was evaluated. silica nanoparticles were synthesized using stöber's method, with their surface activated to covalently bind to, and immobilize, protein a. for biolabeling, fsnp was added to conjugated e. histolytica trophozoites with monoclonal anti-e. histolytica igg1 for microscopic observation of fluorescence. fluorescent silica nanoparticle sensitivity was determine ... | 2015 | 25697865 |
| entamoeba infections in different populations of dogs in an endemic area of lahore, pakistan. | entamoeba histolytica, a protozoan parasite that affects humans and other primates all over the world. it is a common waterborne pathogen in endemic areas that have fecal oral transmission cycle. the aim of the present study was to examine the prevalence of e. histolytica and other entamoeba species cysts in three different dog populations. fecal samples from 600 dogs were collected and processed to detect entamoeba cysts using the triple fecal test (light microscopy) and fecal antigens of e. hi ... | 2015 | 25557213 |
| prevalence of entamoeba histolytica/entamoeba dispar in the city of campina grande, in northeastern brazil. | there is a clear need to perform epidemiological studies to find the true prevalence of entamoeba histolytica around the world. the evaluation of this prevalence has been hindered by the existence of two different species which are morphologically identical, but genetically different, namely e. histolytica, which causes amebiasis, and e. dispar, which is non-pathogenic. in brazil, the e. dispar has been detected in communities in the southeastern (se) and northeastern (ne) regions with poor sani ... | 2015 | 25229229 |
| molecular epidemiology of amoebiasis: a cross-sectional study among north east indian population. | epidemiological studies carried out using culture or microscopy in most of the amoebiasis endemic developing countries, yielded confusing results since none of these could differentiate the pathogenic entamoeba histolytica from the non-pathogenic entamoeba dispar and entamoeba moshkovskii. the northeastern part of india is a hot spot of infection since the climatic conditions are most conducive for the infection and so far no systemic study has been carried out in this region. | 2015 | 26633890 |
| [investigation on entamoeba histolytica infection in diarrhea patients from general hospitals in shanghai city]. | to understand the status of entamoeba histolytica infection in diarrhea patients in general hospitals, so as to provide the evidences for the prevention and control of the disease. | 2015 | 27097477 |
| the first case of huge amebic intra-abdominal tumor with asymptomatic amebic colitis. | we report a rare case of huge amebic intra-abdominal tumor with asymptomatic amebic colitis. this appears to represent the first report of amebic intra-abdominal tumor. a 31-year-old woman presented to a local doctor with only a sensation of abdominal fullness. abdominal computed tomography (ct) showed a huge intra-abdominal tumor in the left abdominal cavity, and she was referred to our hospital. colonofiberscopy for detailed examination showed multiple slight, discrete ulcers in the cecum. ame ... | 2015 | 26366345 |
| novel hemagglutinating, hemolytic and cytotoxic activities of the intermediate subunit of entamoeba histolytica lectin. | galactose and n-acetyl-d-galactosamine (gal/galnac) inhibitable lectin of entamoeba histolytica, a common protozoan parasite, has roles in pathogenicity and induction of protective immunity in mouse models of amoebiasis. the lectin consists of heavy (hgl), light (lgl), and intermediate (igl) subunits. hgl has lectin activity and lgl does not, but little is known about the activity of igl. in this study, we assessed various regions of igl for hemagglutinating activity using recombinant proteins e ... | 2015 | 26354528 |
| a whole-genome rnai screen uncovers a novel role for human potassium channels in cell killing by the parasite entamoeba histolytica. | the parasite entamoeba histolytica kills human cells resulting in ulceration, inflammation and invasion of the colonic epithelium. we used the cytotoxic properties of ameba to select a genome-wide rnai library to reveal novel host factors that control susceptibility to amebic killing. we identified 281 candidate susceptibility genes and bioinformatics analyses revealed that ion transporters were significantly enriched among susceptibility genes. potassium (k(+)) channels were the most common tra ... | 2015 | 26346926 |
| a surface membrane protein of entamoeba histolytica functions as a receptor for human chemokine il-8: its role in the attraction of trophozoites to inflammation sites. | entamoeba histolytica trophozoites respond to the presence of il-8, moving by chemotaxis towards the source of the chemokine. il-8 binds to the trophozoite membrane and triggers a response that activates signaling pathways that in turn regulate actin/myosin cytoskeleton organisation to initiate migration towards the chemokine, suggesting the presence of a receptor for il-8 in the parasite. antibodies directed to the human il-8 receptor (cxcr1) specifically recognised a 29 kda protein in trophozo ... | 2015 | 26343219 |
| entamoeba invadens: identification of a serca protein and effect of serca inhibitors on encystation. | calcium has an important role on signaling of different cellular processes, including growth and differentiation. signaling by calcium also has an essential function in pathogenesis and differentiation of the protozoan parasites entamoeba histolytica and entamoeba invadens. however, the proteins of these parasites that regulate the cytoplasmic concentration of this ion are poorly studied. in eukaryotic cells, the calcium-atpase of the serca type plays an important role in calcium homeostasis by ... | 2015 | 26318877 |
| enhancing protein capture using a combination of nanoyeast single-chain fragment affinity reagents and alternating current electrohydrodynamic forces. | new high-performance detection technologies and more robust protein capture agents can be combined to both rapidly and specifically capture and detect protein biomarkers associated with disease in complex biological samples. here we demonstrate the use of recently developed recombinant affinity reagents, namely nanoyeast-scfv, in combination with alternating current electrohydrodynamic (ac-ehd)-induced shear forces, to enhance capture performance during protein biomarker analysis. the use of ac- ... | 2015 | 26551436 |
| intestinal parasitic infections among children under five years of age presenting with diarrhoeal diseases to two public health facilities in hawassa, south ethiopia. | diarrhoea is the leading cause of morbidity and mortality in children under 5 years of age in developing countries, including ethiopia. it is caused by a wide range of pathogens, including parasites, bacteria and viruses. the aim of this study was to determine the prevalence of infection with intestinal parasites (ips) (and types) among children under 5 years of age with diarrhoeal diseases. | 2015 | 26530964 |
| heat shock protein 90 regulates encystation in entamoeba. | enteric protozoan entamoeba histolytica is a major cause of debilitating diarrheal infection worldwide with high morbidity and mortality. even though the clinical burden of this parasite is very high, this infection is categorized as a neglected disease. parasite is transmitted through feco-oral route and exhibit two distinct stages namely - trophozoites and cysts. mechanism and regulation of encystation is not clearly understood. previous studies have established the role of heat shock protein ... | 2015 | 26528271 |
| ethanol and isopropanol in concentrations present in hand sanitizers sharply reduce excystation of giardia and entamoeba and eliminate oral infectivity of giardia cysts in gerbils. | enteric protozoan parasites, which are spread by the fecal-oral route, are important causes of diarrhea (giardia duodenalis) and amebic dysentery (entamoeba histolytica). cyst walls of giardia and entamoeba have a single layer composed of fibrils of β-1,3-linked galnac and β-1,4-linked glcnac (chitin), respectively. the goal here was to determine whether hand sanitizers that contain ethanol or isopropanol as the active microbicide might reduce transmission of these parasites. we found that treat ... | 2015 | 26282413 |
| taking a bite: amoebic trogocytosis in entamoeba histolytica and beyond. | entamoeba histolytica is a diarrheal pathogen with the ability to cause profound host tissue damage. this organism possesses contact-dependent cell killing activity, which is likely to be a major contributor to tissue damage. e. histolytica trophozoites were recently shown to ingest fragments of living human cells. it was demonstrated that this process, termed amoebic trogocytosis, contributes to cell killing. recent advances in ex vivo and 3-d cell culture approaches have shed light on mechanis ... | 2015 | 26277085 |
| multiple amoebic liver abscess as initial manifestation in hiv sero-positive male. | amoebic liver abscess is the most frequent extra-intestinal manifestation of entamoeba histolytica infection. immunosuppression is known to predispose to amoebic liver abscess. although amoebic liver abscess is seen more commonly in patients of human-immunodeficiency virus (hiv), first presentation of hiv sero-positive patient as multiple liver abscess is quite uncommon.the author reports an unusual case of multiple liver abscesses in an hiv seropositive patient. this middle aged male with histo ... | 2015 | 26266151 |
| magnetic removal of entamoeba cysts from water using chitosan oligosaccharide-coated iron oxide nanoparticles. | amebiasis, a major health problem in developing countries, is the second most common cause of death due to parasitic infection. amebiasis is usually transmitted by the ingestion of entamoeba histolytica cysts through oral-fecal route. herein, we report on the use of chitosan oligosaccharide-functionalized iron oxide nanoparticles for efficient capture and removal of pathogenic protozoan cysts under the influence of an external magnetic field. these nanoparticles were synthesized through a chemic ... | 2015 | 26261417 |
| the effect of ifn-γ and tgf-β in the functional activity of mononuclear cells in the presence of entamoeba histolytica. | entamoeba histolytica (e. histolytica) causes amoebiasis, which is a disease with significant morbidity and mortality. phagocytic cells and cytokines appear to be important in amoebiasis, but very little is known about the influence of these cells and cytokines in protozoan infections. the aim of this study was to analyse the supernatant of cultures of mononuclear (mn) cells with e. histolytica to determine: 1) the levels of the cytokines ifn-γ and tgf-β, and 2) the amoebicidal activity of mn ce ... | 2015 | 26249205 |
| high throughput sequencing of entamoeba 27nt small rna population reveals role in permanent gene silencing but no effect on regulating gene expression changes during stage conversion, oxidative, or heat shock stress. | the human parasite entamoeba histolytica has an active rna interference (rnai) pathway with an extensive repertoire of 27nt small rnas that silence genes. however the role of this pathway in regulating amebic biology remains unknown. in this study, we address whether silencing via 27nt small rnas may be a mechanism for controlling gene expression changes during conversion between the trophozoite and cyst stages of the parasite. we sequenced small rna libraries generated from trophozoites, early ... | 2015 | 26248204 |
| post-transcriptional regulation of ribosomal protein genes during serum starvation in entamoeba histolytica. | ribosome synthesis involves all three rna polymerases which are co-ordinately regulated to produce equimolar amounts of rrnas and ribosomal proteins (rps). unlike model organisms where transcription of rrna and rp genes slows down during stress, in e. histolytica rdna transcription continues but pre-rrna processing slows down and unprocessed pre-rrna accumulates during serum starvation. to investigate the regulation of rp genes under stress we measured transcription of six selected rp genes from ... | 2015 | 26247142 |
| ehvps32 is a vacuole-associated protein involved in pinocytosis and phagocytosis of entamoeaba histolytica. | here, we investigated the role of ehvps32 protein (a member of the endosomal-sorting complex required for transport) in endocytosis of entamoeba histolytica, a professional phagocyte. confocal microscopy, tem and cell fractionation revealed ehvps32 in cytoplasmic vesicles and also located adjacent to the plasma membrane. between 5 to 30 min of phagocytosis, ehvps32 was detected on some erythrocytes-containing phagosomes of acidic nature, and at 60 min it returned to cytoplasmic vesicles and also ... | 2015 | 26230715 |
| a single rnaseiii domain protein from entamoeba histolytica has dsrna cleavage activity and can help mediate rnai gene silencing in a heterologous system. | dicer enzymes process double-stranded rna (dsrna) into small rnas that target gene silencing through the rna interference (rnai) pathway. dicer enzymes are complex, multi-domain rnaseiii proteins, however structural minimalism of this protein has recently emerged in parasitic and fungal systems. the most minimal dicer, saccharomyces castellii dicer1, has a single rnaseiii domain and two double stranded rna binding domains. in the protozoan parasite entamoeba histolytica 27nt small rnas are abund ... | 2015 | 26230096 |
| ent-kaurene glycosides from ageratina cylindrica. | the aqueous extract of the leaves of ageratina cylindrica afforded six new ent-kaurenoic acid glycosides together with the known diterpenoid paniculoside v, the flavonoid astragalin, chlorogenic acid, and l-chiro-inositol. the structures were elucidated mainly by nmr and ms methods, and the absolute configuration was established by vibrational circular dichroism spectroscopy. the new compounds showed moderate antiprotozoal activity against entamoeba histolytica and giardia lamblia trophozoites. | 2015 | 26517282 |
| determining intestinal parasitic infections (ipis) in inmates from kajang prison, selangor, malaysia for improved prison management. | the prison management in malaysia is proactively seeking to improve the health status of the prison inmates. intestinal parasitic infections (ipis) are widely distributed throughout the world and are still gaining great concern due to their significant morbidity and mortality among infected humans. in malaysia, there is a paucity of information on ipis among prison inmates. in order to further enhance the current health strategies employed, the present study aims to establish firm data on the pr ... | 2015 | 26511347 |
| calpain-like: a ca(2+) dependent cystein protease in entamoeba histolytica cell death. | entamoeba histolytica programmed cell death (pcd) induced by g418 is characterized by the release of important amounts of intracellular calcium from reservoirs. nevertheless, no typical caspases have been detected in the parasite, the pcd phenotype is inhibited by the cysteine protease inhibitor e-64. these results strongly suggest that ca(2+)-dependent proteases could be involved in pcd. in this study, we evaluate the expression and activity of a specific dependent ca(2+) protease, the calpain- ... | 2015 | 26496790 |
| new drug target in protozoan parasites: the role of thioredoxin reductase. | amebiasis causes approximately 70,000 deaths annually and is the third cause of death due to parasites worldwide. it is treated primarily with metronidazole, which has adverse side effects, is mutagenic and carcinogenic, and emergence of resistance is an increasing concern. unfortunately, better therapeutic alternatives are lacking. re-purposing of older fda approved drugs is advantageous to drug discovery since safety and pharmacokinetic effects in humans are already known. in high throughput s ... | 2015 | 26483758 |
| [mean platelet volume in children with acute gastroenteritis caused by entamoeba histolytica]. | mean platelet volume (mpv) is a marker of platelet activation, which is a determinant of inflammation. the first aim of the present study was to investigate the mpv levels in children with amebiasis and compare the mpv levels with healthy controls. the second aim of this study was to evaluate the relationship between mpv and other acute phase reactants. | 2015 | 26470926 |
| [evaluation of two methods (nativ-lugol preparation and enzyme-linked immunosorbent assay) for detection of entamoeba histolytica in stool samples]. | this study aims to compare the performance of native-lugol examination and eia antigen detection test using stool samples obtained from patients diagnosed as clinical gastroenteritis and submitted to the parasitology laboratory in uludağ university between january 2010 and february 2011. | 2015 | 26470922 |
| molecular epidemiology of entamoeba: first description of entamoeba moshkovskii in a rural area from central colombia. | entamoeba histolytica, e. dispar and e. moshkovskii are the most frequent species described in human infection where e. histolytica is the only true pathogen. the epidemiology of this infection is complex due to the absence of a routine exam that allows a correct discrimination of the entamoeba species complex. therefore, molecular methods appear as the unique epidemiological tool to accomplish the species discrimination. herein, we conducted a cross-sectional study to determine the frequency of ... | 2015 | 26465744 |
| amoeboid movement in protozoan pathogens. | entamoeba histolytica, the causative agent of amoebiasis, is a protozoan parasite characterised by its amoeboid motility, which is essential to its survival and invasion of the human host. elucidating the molecular mechanisms leading to invasion of human tissues by e. histolytica requires a quantitative understanding of how its cytoskeleton deforms and tailors its mode of migration to the local microenvironment. here we review the wide range of methods available to extract biophysical informatio ... | 2015 | 26459974 |
| identification of natural inhibitors of entamoeba histolytica cysteine synthase from microbial secondary metabolites. | amebiasis is a common worldwide diarrheal disease, caused by the protozoan parasite, entamoeba histolytica. metronidazole has been a drug of choice against amebiasis for decades despite its known side effects and low efficacy against asymptomatic cyst carriers. e. histolytica is also capable of surviving sub-therapeutic levels of metronidazole in vitro. novel drugs with different mode of action are therefore urgently needed. the sulfur assimilatory de novo l-cysteine biosynthetic pathway is esse ... | 2015 | 26441896 |
| characterization of the protein tyrosine phosphatase prl from entamoeba histolytica. | protein tyrosine phosphatase of regenerating liver (prl) is a group of phosphatases that has not been broadly studied in protozoan parasites. in humans, prls are involved in metastatic cancer, the promotion of cell migration and invasion. ptps have been increasingly recognized as important effectors of host-pathogen interactions. we characterized the only putative protein tyrosine phosphatase prl (ptp ehprl) in the eukaryotic human intestinal parasite entamoeba histolytica. here, we reported tha ... | 2015 | 26431820 |
| intestinal amoebiasis in a patient with acute graft-versus-host disease after allogeneic bone marrow transplantation successfully treated by metronidazole. | amoebiasis has rarely been reported in patients undergoing hematopoietic stem cell transplantation, although it is a world-wide infection and extremely common. we present a case of intestinal amoebiasis unexpectedly revealed by colonoscopy after allogeneic bone marrow transplantation from a human leukocyte antigen-mismatched unrelated donor for acute myeloid leukemia arising from chronic myelomonocytic leukemia and successfully treated by metronidazole. | 2015 | 26426525 |
| entamoeba histolytica dmc1 catalyzes homologous dna pairing and strand exchange that is stimulated by calcium and hop2-mnd1. | meiosis depends on homologous recombination (hr) in most sexually reproducing organisms. efficient meiotic hr requires the activity of the meiosis-specific recombinase, dmc1. previous work shows dmc1 is expressed in entamoeba histolytica, a eukaryotic parasite responsible for amoebiasis throughout the world, suggesting this organism undergoes meiosis. here, we demonstrate dmc1 protein is expressed in e. histolytica. we show that purified ehdmc1 forms presynaptic filaments and catalyzes atp-depen ... | 2015 | 26422142 |
| the amoebicidal effect of ergosterol peroxide isolated from pleurotus ostreatus. | dysentery is an inflammation of the intestine caused by the protozoan parasite entamoeba histolytica and is a recurrent health problem affecting millions of people worldwide. because of the magnitude of this disease, finding novel strategies for treatment that does not affect human cells is necessary. ergosterol peroxide is a sterol particularly known as a major cytotoxic agent with a wide spectrum of biological activities produced by edible and medicinal mushrooms. the aim of this report is to ... | 2015 | 26392373 |
| is procalcitonin increased in cases of invasive amoebiasis? a retrospective, observational study. | procalcitonin (pct) levels are commonly used for diagnostic guidance in routine bacterial infections. by contrast, little data are currently available regarding pct in parasitic diseases, and its role in cases of invasive amoebiasis has not yet been described. for this purpose, 35 adult patients with a proven diagnosis of invasive or digestive amoebiasis were included in a 4-year study period. serum pct was retrospectively assessed. results were analysed with regard to the usual inflammatory bio ... | 2015 | 26388549 |
| evidence that the entamoeba histolytica mitochondrial carrier family links mitosomal and cytosolic pathways through exchange of 3'-phosphoadenosine 5'-phosphosulfate and atp. | entamoeba histolytica, a microaerophilic protozoan parasite, possesses mitosomes. mitosomes are mitochondrion-related organelles that have largely lost typical mitochondrial functions, such as those involved in the tricarboxylic acid cycle and oxidative phosphorylation. the biological roles of entamoeba mitosomes have been a long-standing enigma. we previously demonstrated that sulfate activation, which is not generally compartmentalized to mitochondria, is a major function of e. histolytica mit ... | 2015 | 26385892 |
| comparison of the anaerocult a and the oil blocking methods for the in vitro cultivation of entamoeba histolytica. | entamoeba histolytica, the causative agent for human amoebiasis, is among the most deadly parasites, accounting for the second highest mortality rate among parasitic diseases. because this parasite dwells in low oxygen tension, for its cultivation, microaerophilic conditions are required to mimick the human gut environment. several methods developed for optimal growth environment are commercially available and some are conventionally modified in-house which include the anaerocult a and oil block ... | 2015 | 26712674 |
| immune evasion mechanisms of entamoeba histolytica: progression to disease. | entamoeba histolytica (eh) is a protozoan parasite that infects 10% of the world's population and results in 100,000 deaths/year from amebic dysentery and/or liver abscess. in most cases, this extracellular parasite colonizes the colon by high affinity binding to muc2 mucin without disease symptoms, whereas in some cases, eh triggers an aggressive inflammatory response upon invasion of the colonic mucosa. the specific host-parasite factors critical for disease pathogenesis are still not well cha ... | 2015 | 26696997 |
| first report of genitourinary amoebiasis in thailand. | genitourinary amoebiasis is a rare form of kidney and urinary tract infection caused by entamoeba histolytica. here, we describe the first case of unusual infection caused by e. histolytica in bueng kan province, northeast, thailand. a 63-year-old female patient was diagnosed as acute pyelonephritis. e. histotolytica trophozoites were accidentally found in urine collected from a catheter. | 2015 | 26695217 |
| scrotal abscess, a rare case of extra intestinal amoebiasis. | the majority of amoeba infection are asymptomatic, but clinically intestinal amoebiasis or extra intestinal amoebiasis may result. genital amoebiasis is very rare manifestation of extra intestial amoebiasis, but a case of amoebic scrotal abscess, seen in surabaya. the invasive form of entamoeba histolytica trophozoite was seen in giemsa stained aspirate of the abscess. in case of an abscess bacteria are primarly considered, but the case presented here shows that amoeba can be the cause, although ... | 2015 | 26695210 |
| methodology for preservation of yeast-bound single chain fragment variable antibody affinity reagents. | readily accessible affinity reagents are critical to the validation of biomarkers and to the development of new diagnostic tests. as alternatives to monoclonal antibodies, yeast-bound single chain fragment variable antibody (yeast-scfv) can be rapidly selected from yeast display libraries. an important characteristic for any diagnostic reagent is its stability or ability to store it. a lyophilization procedure that has extended the shelf life of yeast-scfv by a factor of ≥10-fold relative to pre ... | 2015 | 26571425 |
| the entamoeba histolytica, arp2/3 complex is recruited to phagocytic cups through an atypical kinase ehak1. | the parasite entamoeba histolytica is the etiological agent of amoebiasis and phagocytosis plays a key role in virulence of this organism. signaling pathways involved in activation of cytoskeletal dynamics required for phagocytosis remain to be elucidated. phagocytosis is initiated with sequential recruitment of ehc2pk, ehcabp1, ehcabp3 and an atypical kinase ehak1 after particle attachment. here we show that eharpc1, an essential subunit of the actin branching complex arp 2/3 is recruited to th ... | 2015 | 26646565 |
| kaempferol inhibits entamoeba histolytica growth by altering cytoskeletal functions. | the flavonoid kaempferol obtained from helianthemum glomeratum, an endemic mexican medicinal herb used to treat gastrointestinal disorders, has been shown to inhibit growth of entamoeba histolytica trophozoites in vitro; however, the mechanisms associated with this activity have not been documented. several works reported that kaempferol affects cytoskeleton in mammalian cells. in order to gain insights into the action mechanisms involved in the anti-amoebic effect of kaempferol, here we evaluat ... | 2015 | 26620675 |
| vagotomy induces deregulation of the inflammatory response during the development of amoebic liver abscess in hamsters. | the parasympathetic nervous system modulates the immune response in the abdominal-pelvic gut through the vagus nerve, which releases acetylcholine. this endogenous ligand acts on α7 nicotinic receptors expressed on immune cells. | 2015 | 24819982 |
| [ameboma: possible therapeutic decisions in an amebiasis-endemic region]. | amebiasis can mimic cecal tumors. unless this infection is diagnosed in a timely manner, affected individuals may undergo extensive surgery. | 2015 | 25195079 |
| headache following occipital brain lesion: a case of migraine triggered by occipital spikes? | this study describes the case of an 8-year-old boy who developed a genuine migraine after the surgical excision, from the right occipital lobe, of brain abscesses due to selective infestation of the cerebrum by entamoeba histolytica. after the surgical treatment, the boy presented daily headaches with typical migraine features, including right-side parieto-temporal pain, nausea, vomiting, and photophobia. electroencephalography (eeg) showed epileptiform discharges in the right occipital lobe, al ... | 2015 | 25406125 |
| cellular and proteomics analysis of the endomembrane system from the unicellular entamoeba histolytica. | entamoeba histolytica is the protozoan parasite agent of amoebiasis, an infectious disease of the human intestine and liver. specific active pathogenic factors are secreted toward the external milieu upon interaction of the parasite with human tissue. trafficking dynamics and secretion of these factors is not known and characterization of the dynamics interplay of subcellular compartments such as the er or golgi apparatus is still pending. in this work, we took advantage of cell fractionation an ... | 2015 | 25109464 |
| in vivo identification of the steps that control energy metabolism and survival of entamoeba histolytica. | the steps that control the entamoeba histolytica glycolytic flux were here identified by elasticity analysis, an experimental approach of metabolic control analysis. the concentrations of glycolytic metabolites were gradually varied in live trophozoites by (a) feeding with different glucose concentrations and (b) inhibiting the final pathway steps; in parallel, the changes in the pathway flux were determined. from the metabolite concentration-flux relationship, the elasticity coefficients of ind ... | 2015 | 25350227 |
| colonoscopic diagnosis of amebiasis: a case series and systematic review. | nonspecific gastrointestinal symptoms make diagnosis of amebiasis difficult. certain colonoscopic findings predict amebic colitis while others suggest different diagnoses. we aimed to evaluate the diagnostic capability of colonic evaluation of amebiasis. | 2015 | 25346004 |
| immunization with the entamoeba histolytica surface metalloprotease ehmsp-1 protects hamsters from amebic liver abscess. | diarrhea and amebic liver abscesses due to invasive entamoeba histolytica infections are an important cause of morbidity and mortality in the developing world. entamoeba histolytica adherence and cell migration, two phenotypes linked to virulence, are both aberrant in trophozoites deficient in the metallosurface protease ehmsp-1, which is a homologue of the leishmania vaccine candidate leishmanolysin (gp63). we examined the potential of ehmsp-1 for use as a vaccine antigen to protect against ame ... | 2015 | 25452550 |
| multisite clinical evaluation of a rapid test for entamoeba histolytica in stool. | rapid point-of-care detection of enteric protozoa in diarrheal stool is desirable in clinical and research settings to efficiently determine the etiology of diarrhea. we analyzed the ability of the third-generation e. histolytica quik chek assay developed by techlab to detect amebic antigens in fecal samples collected from independent study populations in south africa and bangladesh. we compared the performance of this recently released rapid test to that of the commercially available prospect e ... | 2015 | 25428152 |
| modulation of endogenous cysteine protease inhibitor (icp) 1 expression in entamoeba histolytica affects amoebic adhesion to extracellular matrix proteins. | entamoeba histolytica is an enteric tissue-invading protozoan parasite that causes amoebic colitis and occasionally liver abscess in humans. during tissue invasion, amoebic adhesion to host components is an important event for host cell death leading to successful invasion and infection. among amoebic virulence factors, gal/galnac lectin is known to be major adhesion factor to host cells. in this study, we investigated the role of amoebic secreted cp (cysteine proteases) in amoebic adhesion to e ... | 2015 | 25500214 |
| ascaris spp. and capillaria caudinflata infections in captive-bred crested ibis (nipponia nippon) in china. | crested ibis (nipponia nippon), an endan gered native bird, was called the "precious stone" of oriental birds. n. nippon was considered a critically endangered species in the iucn red list of threatened species and a first-class national protected animal in china. the chinese government had exerted considerable effort to protect the n. nippon population. an effective approach to increase the number of these birds was captive breeding. however, several pathogens, including parasites, could jeopar ... | 2015 | 25486916 |
| pulmonary thromboembolism complicating amebic liver abscess: first reported case in the united states-case report and literature review. | even in the absence of amebic colitis, amebic liver abscess (ala) is the most common extraintestinal complication of entamoeba histolytica infection. in the usa, it is most prevalent in middle aged immigrant males from endemic countries such as africa, mexico, and india. one of the complications of ala is inferior vena cava (ivc) thrombosis, which is believed to result from the mechanical compression of the ivc and the consequent thrombogenic nidus elicited from the resultant inflammatory respon ... | 2015 | 26294987 |
| synthesis and characterization with antineoplastic, biochemical, cytotoxic, and antimicrobial studies of schiff base cu(ii) ion complexes. | copper(ii) complexes containing two schiff base ligands derived from 2-hydroxybenzaldehyde with 2-aminophenol and 3-aminophenol have been synthesized and characterized by means of analytical, magnetic, and spectroscopic methods. bacteria, fungus, entamoeba histolytica, and antineoplastic activities of the synthesized complexes have been determined by monitoring the parameters cell growth inhibition, survival time of tumour mice, time-body relation, causing of intraperitoneal cells and macrophage ... | 2015 | 26294901 |
| fatal case of amoebic liver abscess in a child. | we reported a case of amoebic liver abscess (ala) in a 6-year-old malaysian boy who presented with fever, lethargy, diarrhoea and right hypochondriac pain. on admission he was diagnosed with perforated acute appendicitis and a laparotomy was done. after surgery he developed acute respiratory distress. ultrasonography, chest x-ray and ct scan revealed two alas in the posterior segment of right lobe of liver, pleural effusion and collapsed consolidation of lungs bilaterally. percutaneous liver abs ... | 2015 | 26522307 |
| a new anthraquinone from morinda elliptica ridl. | a new anthraquinone, morinquinone, together with 18 known anthraquinones were isolated from the stems of morinda elliptica ridl. their structures were elucidated on the basis of spectroscopic data. they each showed weak inhibitory activity against a susceptible strain of staphylococcus aureus and a methicillin-resistant s. aureus. damnacanthal was effective against microsporum gypseum (mic 1 μg/ml). lucidin was active against entamoeba histolytica (mic 31.25 μg/ml) and giardia intestinalis (mic ... | 2015 | 25686628 |
| molecular and functional characterisation of a stress responsive cysteine protease, ehcp6 from entamoeba histolytica. | entamoeba histolytica cysteine protease 6 (ehcp6) is a stress responsive cysteine protease that is upregulated in response to heat shock and during pathogen invasion of the host tissue. in the present study an attempt has been made to express and purify recombinant ehcp6 in order to gain insights into its biochemical properties. the recombinant and refolded protein has been shown to undergo autoproteolysis in the presence of dtt and sds to give rise to ∼25kda mature form. the mature form of the ... | 2015 | 25680771 |
| a pcr-rflp method for the simultaneous differentiation of three entamoeba species. | amoebiasis caused by entamoeba histolytica continues to be one of the most common parasitic diseases in the developing world. despite its relevance, due to the lack of accurate diagnostic methods, the true clinical and public health importance of this parasite remains uncertain. the aim of this study was to develop a new diagnostic tool to differentiate e.histolytica from the morphologically undistinguishable e.dispar and e.moshkovskii. we developed a specific, fast and simple pcr-rflp method th ... | 2015 | 25680279 |
| importance of microscopic stool examination in patients with diarrhoea. | loose motion is a common symptom in patients reporting to our hospital. as it is a small set up where only facility for microscopic stool examination is available, we designed this study to know how much microscopic stool examination can help us in management of patients with diarrhoea. | 2015 | 25672169 |
| entamoeba histolytica: adhesins and lectins in the trophozoite surface. | entamoeba histolytica is the causative agent of amebiasis in humans and is responsible for 100,000 deaths annually, making it the third leading cause of death due to a protozoan parasite. pathogenesis appears to result from the potent cytotoxic activity of the parasite, which kills host cells within minutes. although the mechanism is unknown, it is well established to be contact-dependent. the life cycle of the parasite alternates with two forms: the resistant cyst and the invasive trophozoite. ... | 2015 | 25671365 |
| comparison of four rapid diagnostic tests, elisa, microscopy and pcr for the detection of giardia lamblia, cryptosporidium spp. and entamoeba histolytica in feces. | microscopy is the diagnostic reference standard for the detection of parasites, but it is labor-intensive and requires experience. rapid diagnostic tests (rdts) can provide an alternative to microscopy. | 2015 | 25615719 |
| maintenance of intracellular hypoxia and adequate heat shock response are essential requirements for pathogenicity and virulence of entamoeba histolytica. | adhesion to cells, cytotoxicity and proteolysis are functions required for virulence and pathogenicity of entamoeba histolytica. however, there was no correlation between these in vitro functions and the early elimination of non-pathogenic e. dispar and non-virulent e. histolytica (nveh) in experimental amoebic liver abscesses developed in hamsters. thus, additional functions may be involved in amoebic pathogenicity and virulence. in the present study, an integral experimental assessment, includ ... | 2015 | 25611463 |
| is the evaluation of entamoeba histolytica infection in hiv-positive patients of any clinical significance? | amoebiasis caused by entamoeba histolytica (e. histolytica) is one of the most problematic parasitic infections worldwide. data regarding the effect of hiv-induced immunodeficiency on the status of e. histolytica infection are sparse in iran. this study aimed to assess the seroprevalence of anti-e. histolytica igg among iranian hiv patients. further, it determined whether the advancement of immunodeficiency accompanies an increased risk of amoebiasis. a total of 91 hiv-infected patients and 91 c ... | 2015 | 25597605 |