Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| microbiota of dentinal caries as assessed by reverse-capture checkerboard analysis. | this study aimed to identify the microbiota of different layers of dentinal caries by using a culture-independent molecular biology approach. | 2010 | 21160186 |
| comparison of the use of the halimeter and the oral chroma™ in the assessment of the ability of common cultivable oral anaerobic bacteria to produce malodorous volatile sulfur compounds from cysteine and methionine. | to compare the use of the halimeter and the oral chroma™ to assess the ability of common oral anaerobic bacteria isolated from the kuwaiti population to produce volatile sulfur compounds (vscs). | 2010 | 21160219 |
| [detection of putative periodontal pathogens of periodontitis with type 2 diabetes]. | to detect the putative periodontal pathogens in the subgingival plaque of chronic periodontitis (cp) patients with type 2 diabetes mellitus (dm) and to discuss the role of the periodontal pathogens in the cp and type 2 dm patients. | 2010 | 21163008 |
| cited2 is activated in ulcerative colitis and induces p53-dependent apoptosis in response to butyric acid. | in ulcerative colitis (uc), fusobacterium varium is significantly detected in patients' mucosa, and butyric acid (ba), abundantly produced by the bacterium, activates the p53 system and induces epithelial apoptosis, as we previously reported. however, factors active in the link between ba and p53 have yet to be clarified. here, we identified a gene activated by ba specifically in uc-associated cancer cell lines and ascertained the mechanism of its activation of p53. | 2010 | 21165656 |
| [tonsillitis in young people--consider fusobacterium necrophorum]. | 2010 | 21179877 | |
| significant pathogens in peritonsillar abscesses. | peritonsillar abscesses (pta) are polymicrobial infections, with a diverse aerobic and anaerobic flora. the aim of the present study is to compare bacteriologic culture results from patients with pta to those from patients undergoing elective tonsillectomy (clinically non-infected tonsils), to better elucidate the pathogenic significance of various isolates. a prospective study was conducted on 36 pta patients undergoing acute tonsillectomy and on 80 electively tonsillectomised patients. fusobac ... | 2010 | 21181222 |
| comparative evaluation of bactericidal potential of four root canal filling materials against microflora of infected non-vital primary teeth. | since complete debridement of the root canals of the primary teeth is not practically possible due to the highly variable root canal anatomy, success of the endodontic therapy depends partly on the use ofantibacterial irrigating agents and root canal filling materials. recent literature indicates that anaerobes comprise a majority of the bacteria in necrotic root canals ofprimary teeth. the study determined the antibacterial effectiveness of four root canal filling materials namely calcium hydro ... | 2010 | 21189760 |
| fusobacterium nucleatum-associated beta-defensin inducer (fad-i): identification, isolation, and functional evaluation. | human β-defensins (hbds) are small, cationic antimicrobial peptides, secreted by mucosal epithelial cells that regulate adaptive immune functions. we previously reported that fusobacterium nucleatum, a ubiquitous gram-negative bacterium of the human oral cavity, induces human β-defensin 2 (hbd2) upon contact with primary oral epithelial cells. we now report the isolation and characterization of an f. nucleatum (atcc 25586)-associated defensin inducer (fad-i). biochemical approaches revealed a ce ... | 2010 | 20847052 |
| oral microbiota, dental caries and periodontal status in smokeless tobacco chewers in karnataka, india: a case-control study. | the aim of the present study was to compare dental caries and periodontal disease status associated with oral microflora among smokeless tobacco chewers and non-chewers. | 2010 | 20847998 |
| antimicrobial activity of sodium citrate against streptococcus pneumoniae and several oral bacteria. | the aim of this study is to assess the antibacterial activity of sodium citrate against streptococcus pneumoniae and several oral bacteria. | 2010 | 20849395 |
| apical root canal microbiota as determined by reverse-capture checkerboard analysis of cryogenically ground root samples from teeth with apical periodontitis. | bacteria located in the apical root canal system potentially participate in the pathogenesis of apical periodontitis. detection and identification of apical bacteria can be compromised because of limitations in conventional sampling and identification procedures. this study identified several bacterial taxa in the apical and middle/coronal segments of primarily infected root canal system by using pulverized root segments and a culture-independent molecular method. | 2010 | 20850664 |
| isolation of a novel bacteriophage specific for the periodontal pathogen fusobacterium nucleatum. | fusobacterium nucleatum is a periodontal pathogen that has been directly associated with the development and progression of periodontal disease, a widespread pathology that affects the support tissues of the tooth. we isolated a new bacteriophage (fnpφ02) that specifically infects this bacterium. transmission electron microscopy showed that the virion is composed of an icosahedral head and a segmented tail. the size of the phage genome was estimated to be approximately 59 kbp of double-stranded ... | 2010 | 20851973 |
| lemierre syndrome and nosocomial transmission of fusobacterium necrophorum from patient to physician. | human-to-human transmission of fusobacterium necrophorum has not been described before. | 2010 | 20862633 |
| isolation of two novel fusobacterium necrophorum variants from sheep in australia. | 2010 | 20869818 | |
| [effect of compound chinese traditional medicine on infected root canal bacteria biofilm]. | to assess the efficacy of compound chinese traditional medicine(ctm), which composed of gallic acid, magnolol and polysaccharide of blettila striata, against the infected root canal bacterial biofilm. | 2010 | 20871960 |
| ovine footrot: new approaches to an old disease. | footrot is a bacterial disease that has substantial economic and welfare impacts in sheep and can be difficult to manage. research is focussed on reducing the impact that footrot has on farmers and their flocks and better understanding the aetiology of the disease. key areas of current research include, developing better vaccines, deploying tailored vaccines in a specific and targeted fashion on individual farms, analysing and developing better farm management practices to suit specific sheep fa ... | 2010 | 20926208 |
| effect of biofilm on the repair bond strengths of composites. | composite restorations degrade during wear, but it is unknown how wear affects the composite surface and influences composite-to-composite bonding in minimally invasive repair. here, it is hypothesized that in vitro exposure of composites to oral biofilm yields clinically relevant degradation of composite surfaces, and its influence on composite-to-composite bonding is determined. biofilms on composite surfaces in vitro increased their roughness and decreased filler particle exposure, except for ... | 2010 | 20940354 |
| bactericidal activity of stabilized chlorine dioxide as an endodontic irrigant in a polymicrobial biofilm tooth model system. | the purpose of this study was to determine bactericidal efficacy of 0.04% stabilized chlorine dioxide, 3% sodium hypochlorite, 2% chlorhexidine gluconate, and sterile distilled water in a polymicrobial biofilm model. | 2010 | 20951304 |
| severe musculoskeletal infection variant in lemierre's syndrome. | lemierre's syndrome is a severe complication of fusobacterium necrophorum oropharyngeal infection associated with metastatic foci of infection, internal jugular vein thrombosis, and septicemia. musculoskeletal manifestations include isolated or multifocal septic arthritis, soft tissue abscesses, pyomyositis, and osteomyelitis. this article describes a case of a variant of lemierre's syndrome in a 17-year-old girl, demonstrating a relentless case of limb infection refractory to multiple surgical ... | 2010 | 20954654 |
| oxygen tension modulates the cytokine response of oral epithelium to periodontal bacteria. | there is an inverse relationship between pocket depth and pocket oxygen tension with deep pockets being associated with anaerobic bacteria. however, little is known about how the host tissues respond to bacteria under differing oxygen tensions within the periodontal pocket. | 2010 | 20955352 |
| murine fetoplacental infection models. | 2010 | 20956576 | |
| setup of an in vitro test system for basic studies on biofilm behavior of mixed-species cultures with dental and periodontal pathogens. | caries and periodontitis are important human diseases associated with formation of multi-species biofilms. the involved bacteria are intensively studied to understand the molecular basis of the interactions in such biofilms. this study established a basic in vitro single and mixed-species culture model for oral bacteria combining three complimentary methods. the setup allows a rapid screening for effects in the mutual species interaction. furthermore, it is easy to handle, inexpensive, and repro ... | 2010 | 20957048 |
| isolation of streptobacillus moniliformis from the blood of a child with acute lymphoblastic leukaemia. | this is an unusual report of isolation of streptobacillus moniliformis from the blood of a male child with acute lymphoblastic leukaemia. no history of rat bite was there, but rats were present in the house. the possible source of infection may be food or water contaminated with rat excreta. whether this bacteria can cause opportunistic infection in leukaemic patients, need to be evaluated further. | 2010 | 20966577 |
| epizootic rabbit enteropathy inoculum (tec4): antibiograms and antibiotic fractionation. | epizootic rabbit enteropathy (ere) emerged and spread in europe within the last 13 years causing major economical loss. the aims of the study was to evaluate antibiograms of tec4, an inoculum composed of an extract of intestinal content of affected rabbits, and to test the potential of different antibiotic-based tec4 fractions to reproduce the disease. twenty nine different antibiotic discs were incubated for determining bacteria resistance. in a complementary study, nine tubes of liquid medium ... | 2010 | 20978841 |
| energy dose parameters affect antimicrobial photodynamic therapy-mediated eradication of periopathogenic biofilm and planktonic cultures. | this study evaluated the in vitro efficacy of a commercially available apdt system in eradication of the periopathogens porphyromonas gingivalis, fusobacterium nucleatum, and aggregatibacter actinomycetemcomitans in both planktonic and biofilm cultures. | 2010 | 20666581 |
| vaccination of mice with porphyromonas gingivalis or fusobacterium nucleatum modulates the inflammatory response, but fails to prevent experimental periodontitis. | to assess the potential of using vaccination with porphyromonas gingivalis or fusobacterium nucleatum, in modulating local subcutaneous inflammatory response and alveolar bone loss following coinfection with both bacteria. | 2010 | 20670341 |
| commentary: a confusing fusobacterium infection. | 2010 | 20680922 | |
| lemierre's syndrome mimicking leptospirosis. | lemierre's syndrome is a suppurative thrombophlebitis involving the internal jugular vein, most commonly associated with fusobacterium necrophorum, usually a complication of oropharyngeal infections. this syndrome is rare and is often overlooked. we present a case of sepsis mimicking initially severe leptospirosis (weil's disease) due to acute febrile illness with multiorgan failure and hyperbilirubinemia. finally, blood cultures revealed fusobacterium necrophorum and computed tomography (ct) de ... | 2010 | 20680923 |
| a brain abscess following dental extractions in a patient with hereditary hemorrhagic telangiectasia. | oral and maxillofacial surgeons must be aware of the potentially life-threatening complications of dental extractions in patients with hereditary haemorrhagic telangiectasia because of their high prevalence of pulmonary arteriovenous fistulas. despite the lack of evidence-based guidelines, antibiotic cover should be given to patients with hht who require oral surgery according to the same rules as those used for patients at high risk of bacterial endocarditis. | 2010 | 20719417 |
| a teenager with sore throat and neck pain. | 2010 | 20724333 | |
| subgingival microbial profiles of smokers with periodontitis. | the subgingival microbiome is largely uncultivated, and therefore, cultivation-based and targeted molecular approaches have limited value in examining the effect of smoking on this community. we tested the hypothesis that the subgingival biofilm is compositionally different in current and never-smokers by using an open-ended molecular approach for bacterial identification. subgingival plaque from deep sites of current and never-smokers matched for disease was analyzed by 16s sequencing. smokers ... | 2010 | 20739702 |
| streptobacillus moniliformis bacteremia in a child: case report. | background: we report a case of bacteremia caused by streptobacillus moniliformis. case presentation and intervention: a 2 years and 3 months female kuwaiti child presented with febrile convulsions, mild cough and vomiting. the patient's history, clinical findings and radiological investigations were reviewed. there was no history of rat/animal bite, but the child had been camping in the desert prior to the illness and may have been exposed to rodent excreta. on two occasions, blood culture spec ... | 2010 | 20639668 |
| examination of periodontal pathogens in stenotic valve specimens and in whole blood samples in patients affected by aortic valve stenosis and chronic periodontitis. | periodontitis may be a risk factor for atherosclerosis and coronary heart disease. the influence of periodontal pathogens in cardiovascular diseases needs further investigation. therefore, the aims of this clinical study are: to test the presence of periodontal bacteria dna in aortic valves and to assess the concomitant presence of the same periodontal bacteria dna in whole blood samples in patients affected by aortic valve stenosis and chronic periodontitis. nineteen consecutive patients (12 ma ... | 2010 | 20646351 |
| lemierre's syndrome with paradoxical emboli. | lemierre's syndrome is a rare anaerobic oropharyngeal infection complicated by internal jugular thrombosis, the predominant etiology is fusobacterium necrophorum. septic emboli to lungs and distant organs have been described, however, to date there have been no published cases associated with embolization across a patent foramen ovale. we describe a case of lemierre's syndrome with septic arterial emboli resulting in multiple cerebral abscesses and cutaneous manifestations. the outcome was favor ... | 2010 | 20647662 |
| the pott's puffy tumor: an unusual complication of frontal sinusitis, methods for its detection. | this is a case report of a pott's puffy tumor, characterized by a subperiosteal abscess associated with frontal bone osteomyelitis, as a consequence of a frontal sinusitis, in a 15-year-old boy. pott's puffy tumor is a rare condition usually seen as a complication of frontal sinusitis and more commonly described in children. given that, superficial temporal artery pseudoaneurysms might be interpreted as a cyst or lipoma, it is imperative that physicians be aware of their presentation. | 2010 | 20653869 |
| lemierre syndrome caused by co-infection by arcanobacterium haemolyticum and fusobacterium necrophorum. | 2010 | 20661621 | |
| proteomic analysis of a noninvasive human model of acute inflammation and its resolution: the twenty-one day gingivitis model. | the 21-day experimental gingivitis model, an established noninvasive model of inflammation in response to increasing bacterial accumulation in humans, is designed to enable the study of both the induction and resolution of inflammation. here, we have analyzed gingival crevicular fluid, an oral fluid comprising a serum transudate and tissue exudates, by lc-ms/ms using fourier transform ion cyclotron resonance mass spectrometry and itraq isobaric mass tags, to establish meta-proteomic profiles of ... | 2010 | 20662485 |
| microbiota around teeth and dental implants in periodontally healthy, partially edentulous patients: is pre-implant microbiological testing relevant? | this study aimed to assess the prevalence of seven periodontal marker pathogens, before implant placement and 1 yr after loading, in periodontally healthy individuals and to assess the long-term effectiveness of pre-implant reduction of pathogens to below threshold levels. in 93 individuals needing single tooth replacement, pooled subgingival microbiological samples from standard sites were cultured and analyzed before implant treatment and 1 yr after loading. threshold levels commonly used in p ... | 2010 | 20662908 |
| production of indole from l-tryptophan and effects of these compounds on biofilm formation by fusobacterium nucleatum atcc 25586. | the l-tryptophan degradation product indole is a purported extracellular signaling molecule that influences biofilm formation in various bacteria. here we analyzed the mechanisms of indole production in fusobacterium nucleatum and the effects of tryptophan and indole on f. nucleatum planktonic and biofilm cells. the amino acid sequence deduced from the fn1943 gene in f. nucleatum atcc 25586 was 28% identical to that deduced from tnaa in escherichia coli, which encodes tryptophanase catalyzing th ... | 2010 | 20472741 |
| lemierre-like syndrome: a series of unique cases. | 2010 | 20488807 | |
| competition between yogurt probiotics and periodontal pathogens in vitro. | to investigate the competition between probiotics in bio-yogurt and periodontal pathogens in vitro. | 2010 | 20491536 |
| identification of immunological parameters associated with the alveolar bone level in periodontal patients. | the present study was performed to clarify the relationship between periodontal disease severity and selected immunological parameters consisting of serum igg titer against periodontopathogenic bacteria, the expression of the helper t-cell cytokine by gingival mononuclear cells, and patients' immunoreactivity to cross-reactive heat shock protein (hsp) epitope peptide from p. gingivalis hsp60. | 2010 | 20498762 |
| in vitro cytokine responses to periodontal pathogens: generalized aggressive periodontitis is associated with increased il-6 response to porphyromonas gingivalis. | generalized aggressive periodontitis (gagp) is an inflammatory condition resulting in destruction of tooth-supporting tissues. we examined the production of il-1beta, il-6, tumour necrosis factor (tnf)-alpha, il-12 and il-10 in cultures of peripheral mononuclear cells (mnc) from 10 patients with gagp and 10 controls stimulated with periodontal pathogens or a control antigen, tetanus toxoid (tt) in the presence of autologous serum. the pathogens used were porphyromonas gingivalis, prevotella inte ... | 2010 | 20500696 |
| luc's abscess: the return of an old fellow. | mastoiditis, subperiosteal abscess and sigmoid vein thrombosis are the most common suppurative complications of acute otitis media (aom). luc's abscess, a subperiosteal temporal collection, is an infrequent complication with a particularly benign course. | 2010 | 20502372 |
| the recolonization hypothesis in a full-mouth or multiple-session treatment protocol: a blinded, randomized clinical trial. | to test recolonization of periodontal lesions after full-mouth scaling and root planing (fm-srp) or multiple session-srp (ms-srp) in a randomized clinical trial and whether fm-srp and ms-srp result in different clinical outcomes. | 2010 | 20507375 |
| mechanical non-surgical treatment of peri-implantitis: a single-blinded randomized longitudinal clinical study. ii. microbiological results. | peri-implantitis is common in patients with dental implants. we performed a single-blinded longitudinal randomized study to assess the effects of mechanical debridement on the peri-implant microbiota in peri-implantitis lesions. | 2010 | 20507380 |
| [reversible metronidazole-induced encephalopathy and hypertrophic olivary degeneration]. | 2010 | 20508563 | |
| effects of a composition containing lactoferrin and lactoperoxidase on oral malodor and salivary bacteria: a randomized, double-blind, crossover, placebo-controlled clinical trial. | we report a clinical trial of the effects of test tablets containing bovine lactoferrin and lactoperoxidase on oral malodor and salivary bacteria. fifteen subjects with volatile sulfur compounds (vscs) in mouth air above the olfactory threshold (h(2)s >1.5 or ch(3)sh >0.5 ng/10 ml) as detected by gas chromatography were enrolled in the trial. either a test or a placebo tablet was ingested twice at 1-h intervals in two crossover phases. mouth air was monitored for vsc levels at the baseline befor ... | 2010 | 20512389 |
| antimicrobial efficacy of 3 oral antiseptics containing octenidine, polyhexamethylene biguanide, or citroxx: can chlorhexidine be replaced? | use of oral antiseptics decreases the bacterial load in the oral cavity. | 2010 | 20518635 |
| oropharyngeal infection with metastatic hand infection: an uncommon variant of lemierre's syndrome. | lemierre's syndrome is caused by acute oropharyngeal infection with septic secondary thrombophlebitis of the internal jugular vein and metastatic infection. fusobacterium necrophorum is the most commonly implicated aetiological agent. the authors present the case of a healthy young man presenting with a history of general malaise and sore throat who developed septic metastatic complications in the left upper limb. he made a complete recovery after treatment with a combination of parenteral antib ... | 2010 | 20527653 |
| gram-negative periodontal bacteria induce the activation of toll-like receptors 2 and 4, and cytokine production in human periodontal ligament cells. | periodontitis is a bacterially induced chronic inflammatory disease. toll-like receptors (tlrs), which could recognize microbial pathogens, are important components in the innate and adaptive immune systems. both qualitatively and quantitatively distinct immune responses might result from different bacteria stimulation and the triggering of different tlrs. this study explores the interaction of porphyromonas gingivalis, prevotella intermedia, fusobacterium nucleatum, and aggregatibacter actinomy ... | 2010 | 20528699 |
| folding of a transcriptionally acting preq1 riboswitch. | 7-aminomethyl-7-deazaguanine (preq(1)) sensitive mrna domains belong to the smallest riboswitches known to date. although recent efforts have revealed the three-dimensional architecture of the ligand-aptamer complex less is known about the molecular details of the ligand-induced response mechanism that modulates gene expression. we present an in vitro investigation on the ligand-induced folding process of the preq(1) responsive rna element from fusobacterium nucleatum using biophysical methods, ... | 2010 | 20534493 |
| [case of subdural empyema caused by porphyromonas and fusobacterium identified by 16s ribosomal rna gene sequence analysis]. | a 24-year-old woman presented subdural empyema developing from sinusitis caused by porphyromonas and fusobacterium infection. she experienced fever and progressive headache with gradually worsening symptoms. neurological examination revealed drowsiness and neck stiffness. a csf examination detected pleocytosis and a low glucose level. gadolinium-enhanced t1-weighted images from brain mri showed thickening enhancement at the leptomeninges in the left frontal to temporal lobes and interhemispheric ... | 2010 | 20535979 |
| detection of antibodies against fusobacterium necrophorum and porphyromonas levii-like species in dairy cattle with papillomatous digital dermatitis. | bovine digital epidermitis involves different pathologies, including pdd, interdigital dermatitis, and foot rot. bacteriological and molecular biological studies suggest that these are multimicrobial infections. during our study on the isolation of treponemes from biopsies of pdd, colonies producing black pigment were isolated frequently from the primary cultures, suggesting that porphyromonas species were present. moreover, 16s rrna genes of fusobacterium necrophorum and porphyromonas levii-lik ... | 2010 | 20536732 |
| antimicrobial activity of n-6, n-7 and n-9 fatty acids and their esters for oral microorganisms. | this study is to assess the antibacterial activity of omega-6, -7, -9 (n-6, n-7, n-9) fatty acids against various oral microorganisms. | 2010 | 20541177 |
| antibiotic resistance of subgingival species in chronic periodontitis patients. | the increasing rate of resistance of microorganisms to penicillin and other antibiotics has generated concern among health authorities in latin america. the present investigation determined the in vitro susceptibility of porphyromonas gingivalis, fusobacterium nucleatum, black-pigmented prevotella spp. and aggregatibacter actinomycetemcomitans to metronidazole, amoxicillin, amoxicillin/clavulanic acid, clindamycin and moxifloxacin in patients with chronic periodontitis. | 2010 | 20546113 |
| [identification of anaerobic bacteria isolated from various clinical specimens and determination of antibiotic susceptibilities]. | routine isolation, identification and susceptibility testing of anaerobic bacteria present several difficulties leading to defects in the determination of local susceptibility patterns which will guide empirical treatment protocols. this study was carried out to identify the anaerobic bacteria isolated from various clinical materials obtained from the suspected patients with anaerobic infection and to determine the antibiotic susceptibilities against several antibiotics. one hundred clinical spe ... | 2010 | 20549955 |
| [usefulness and limit of gram staining smear examination]. | gram staining is one of the most simple and inexpensive methods for the rapid diagnosis of bacterial and fungal infections. it yields results much faster than culture, and provides important data for the patient's treatment and prognosis. however, a difference exists in the quality and quantity of information yielded by gram staining smears based on the experience and knowledge of those conducting the tests. therefore, a risk of misdiagnosis based on the information obtained from gram staining s ... | 2010 | 20560458 |
| fusobacterium septicemia complicated by cerebral subdural and epidural empyemas: a rare case of lemierre syndrome. | background: lemierre syndrome is characterized by postanginal septicemia and internal jugular vein thrombophlebitis with secondary septic emboli, typically to the lungs. the central nervous system (cns) is rarely involved. objective: to present a case of lemierre syndrome featuring cerebral subdural and epidural empyemas. case report: this case report describes the case of a 17-year-old youth with cerebral subdural and epidural empyemas. the findings of chest computed tomography of the neck and ... | 2010 | 20566261 |
| [lemierre syndrome: several clinical features of "a forgotten disease"]. | lemierre syndrome (ls) is considered as a forgotten disease since the beginning of penicillin. the lack of use of beta-lactamase inhibitors antibiotics together with the increase in the use of macrolids or second-generation and third-generation cephalosporins for oropharyngeal processes has led to an increasing incidence. we propose to review all ls cases seen in an emergency department over the last 5 years. | 2010 | 20570017 |
| lemierre syndrome from an odontogenic source: a review for dentists. | lemierre syndrome, which can result from a recent oropharyngeal or odontogenic infection, is characterized by clinical or radiographic signs of thrombosis of the internal jugular vein, distant infected emboli and the presence of anaerobic pathogens, usually fusobacterium necrophorum. the septic emboli resulting from the infected thrombophlebitis of the internal jugular vein give the syndrome its constellation of central nervous system, pulmonary and many other manifestations including septic sho ... | 2010 | 20579443 |
| neurological complications in two children with lemierre syndrome. | lemierre syndrome is a distinct clinical syndrome comprising oropharyngeal sepsis and fever, internal jugular vein thrombosis and remote septic metastases caused by fusobacterium species. the mortality rate was historically high and although use of antibiotics led to a dramatic fall in incidence, a resurgence has been seen recently. a 14-year-old male developed lemierre syndrome after tonsillitis. there was extensive leptomeningitis, especially over the clivus, causing 6th and 12th cranial nerve ... | 2010 | 20584047 |
| use of a sustained release chlorhexidine varnish as treatment of oral necrobacillosis in macropus spp. | oral necrobacillosis or lumpy jaw is a common cause of morbidity and mortality affecting captive macropods. this article describes several cases of a new treatment regimen using a sustained release chlorhexidine varnish applied locally to the teeth and the gingivae of two macropus species, eastern grey kangaroos (macropus gigantus) from gan-garoo australian park and a red-necked wallaby (macropus rufogriseus fruticus) from the tisch family zoological gardens in jerusalem. the varnish was applied ... | 2010 | 20597238 |
| lemierre's and lemierre's-like syndromes in association with infectious mononucleosis. | this study aimed to review cases of lemierre's and lemierre's-like syndromes in paediatric patients, to examine a possible association with epstein-barr virus as a predisposing factor, and to assess the impact of this virus on the severity of illness. | 2010 | 20602850 |
| [fever and dysphagia of a young woman]. | we report the case of a 39-year old patient with septicemia treated for pharyngitis with antibiotics since a few days. she wasn't able to swallow her antibiotics anymore because of dysphagia. radiologic examination revealed pulmonary infiltrates and vena iugularis interna-thrombosis. these findings and anamnesis led to the diagnosis of lemierre syndrome inspite of lacking detection of bacteria. after changing the antibiotic therapy and start of anticoagulation further course of illness was favor ... | 2010 | 20607669 |
| hiv-1 reactivation induced by the periodontal pathogens fusobacterium nucleatum and porphyromonas gingivalis involves toll-like receptor 2 [corrected] and 9 activation in monocytes/macrophages. | although oral coinfections (e.g., periodontal disease) are highly prevalent in human immunodeficiency virus type 1-positive (hiv-1(+)) patients and appear to positively correlate with viral load levels, the potential for oral bacteria to induce hiv-1 reactivation in latently infected cells has received little attention. we showed that hiv-1 long terminal repeat (ltr) promoter activation can be induced by periodontopathogens in monocytes/macrophages; nevertheless, the mechanisms involved in this ... | 2010 | 20610663 |
| differential and coordinated expression of defensins and cytokines by gingival epithelial cells and dendritic cells in response to oral bacteria. | epithelial cells and dendritic cells (dcs) both initiate and contribute to innate immune responses to bacteria. however, much less is known about the coordinated regulation of innate immune responses between gecs and immune cells, particularly dcs in the oral cavity. the present study was conducted to investigate whether their responses are coordinated and are bacteria-specific in the oral cavity. | 2010 | 20618959 |
| new aspects and new concepts of maintaining "microbiological" health. | the human mouth is host to a diverse collection of microorganisms including bacteria, viruses, fungi and protozoa. recent advances using molecular methods for the analysis of complex bacterial communities have demonstrated the richness of the oral bacterial biota and the presence of numerous previously undescribed lineages. dental plaque forms in a structured way with pioneer species able to colonise pellicle-coated enamel followed by secondary plaque formers such as fusobacterium nucleatum that ... | 2010 | 20621241 |
| [study of putative periodontal pathogens colonies in type 2 diabetes with chronic periodontitis]. | ppurpose: to study the permanent planting of periodontal pathogens in the subgingival plaque of periodontitis patients with type 2 diabetes, and evaluate role of periodontal pathogens in chronic periodontitis and type 2 diabetes. | 2010 | 21431261 |
| modeling of diffusion transport through oral biofilms with the inverse problem method. | the purpose of this study was to develop a mathematical model to quantitatively describe the passive transport of macromolecules within dental biofilms. | 2010 | 21404968 |
| development of species-specific polymerase chain reaction primers for detection of fusobacterium periodonticum. | the purpose of this study was to develop species-specific pcr primers for detection of fusobacterium periodonticum. the specificity data showed that two sets of pcr primers, fp-f3/fp-r2 and fp-f1/fp-r2 pcr, produced amplicons from all the f. periodonticum, but not from the other species tested, which included 12 fusobacterium species or subspecies and representative oral bacteria. the sensitivity of the primer sets was 4 or 40 pg of the chromosomal dna from f. periodonticum atcc 33693(t) . these ... | 2010 | 21223363 |
| myrsinoic acid b inhibits the production of hydrogen sulfide by periodontal pathogens in vitro. | recently, we reported that myrsinoic acid b purified from myrsine seguinii inhibited methyl mercaptan (ch(3)sh) production by fusobacterium nucleatum jcm8532. since hydrogen sulfide (h(2)s) is the main component of physiological halitosis, while ch(3)sh is involved in pathological oral halitosis, the objective of this study is to determine whether myrsinoic acid b inhibits h(2)s production by oral microorganisms. f. nucleatum, porphyromonas gingivalis and treponema denticola were incubated with ... | 2010 | 21383473 |
| preterm low birthweight and the role of oral bacteria. | preterm and low birthweight (ptlbw) continues to be a major cause of mortality and morbidity across the world. in recent years, maternal periodontal disease has been implicated as a risk factor for adverse pregnancy outcomes. there is conflicting evidence to support such an outcome as illustrated by descriptive, case control and randomised controlled trials involving pregnant women from across the world, using different measurement tools to determine the level of periodontal disease. whilst cons ... | 2010 | 21523222 |
| osteoradionecrosis contains a wide variety of cultivable and non-cultivable bacteria. | direct microscopy, anaerobic culture and dna-dna hybridization have previously demonstrated an association between microorganisms and osteoradionecrosis (orn). the purpose of our study was to use culture independent molecular techniques to detect bacteria in necrotic bone lesions of the mandible after radiation therapy. | 2010 | 21523230 |
| differential effects of periopathogens on host protease inhibitors slpi, elafin, scca1, and scca2. | secretory leukocyte peptidase inhibitors (slpi), elafin, squamous cell carcinoma antigen 1 and 2 (scca1 and scca2) are specific endogenous serine protease inhibitors expressed by epithelial cells that prevent tissue damage from excessive proteolytic enzyme activity due to inflammation. to determine the effects of various periopathogens on these protease inhibitors, we utilized human gingival epithelial cells (gecs) challenged with cell-free bacteria supernatants of various periopathogens porphyr ... | 2010 | 21523231 |
| [lemierre syndrome]. | lemierre's syndrome is a rare and severe condition, with a primary focus in the cervicofacial area and followed by thrombosis of the internal jugular vein and metastatic infections, most often pulmonary. the principal pathogen is fusobacterium necrophorum. less rare and associated with high mortality before antibiotics, lemierre syndrome had became exceptional until the increase in the number of cases in recent years. recovery is usually the rule, but often only after long convalescence and ofte ... | 2010 | 19914026 |
| bacterial diversity in persistent periapical lesions on root-filled teeth. | the purpose of this study was to analyze the bacterial diversity in persistent apical lesions on root-filled teeth by using culture-independent molecular methods. | 2009 | 21523213 |
| vaccine preparation by radiation processing. | a new radiation biotechnology for the acquirement of a commercial vaccine, designed for prophylaxis of ruminant infectious pododermatitis (ip), produced by gram negative bacteria fusobacterium necrophorum (f.n.), is presented. two different processes for preparing f.n. vaccine are used: a) the inactivation of f.n. bacteria exotoxins by microwave (mw) or/and electron beams (eb) irradiation; b) the isolation of exotoxins from f.n. cultures irradiated with mw or/and eb and the inactivation of isola ... | 2009 | 21384715 |
| unusual findings and diagnostic challenges in a child with lemierre's disease. | 16s rdna polymerase chain reaction (pcr) in the diagnosis of fastidious organisms is becoming increasingly commonplace. we present the case of a child admitted to an acute paediatric unit of a university teaching hospital with otorrhoea, torticollis, and cervical lymphadenopathy. examination revealed hepatosplenomegaly associated with pancytopenia. radiological imaging confirmed a retropharyngeal abscess, bilateral mastoiditis, cerebellar lesions, and venous sinus thrombosis. swabs of aural disc ... | 2009 | 21833343 |
| factors contributing to the spread of odontogenic infections: a prospective pilot study. | spreading odontogenic infections (soi) are the commonest type of serious infections encountered in the orofacial region. a prospective multi-centre study was conducted in the west of scotland to investigate the contributing role of social, systemic and microbial factors in the pathogenesis of soi. | 2009 | 21509313 |
| lemierre syndrome: once seen it can never be mistaken. | lemierre syndrome is a rare but severe septicaemia due most frequently to fusobacterium necrophorum, with primary foci in the head, internal jugular vein thrombosis and metastatic infections, mainly in the lungs. we report two cases of lemierre syndrome admitted to the paediatric unit of our hospital at 2-month intervals. the first was 10 years old and the second one was a 3-month-old infant. they were diagnosed on the 25th hospital day and at the time of admission, respectively. in the first ca ... | 2009 | 21686487 |
| more than just drainage. | 2009 | 20830965 | |
| bacterial colonization of oral implants from nondental sources. | implants showing signs of peri-implantitis harbor a microbiota similar to that of periodontitis-affected teeth. this case report describes the subgingival microbiota of a 45-year-old female with advanced periodontitis before and after complete edentulation and reconstruction with dental implants. a 3-month healing period post extraction passed before implants were placed using a two-stage submerged implant protocol. at 4- to 6-month recall visits after definitive prosthetic reconstruction, some ... | 2009 | 18657153 |
| biomaterial and antibiotic strategies for peri-implantitis: a review. | dental implants have 89% plus survival rates at 10-15 years, but peri-implantitis or dental implant infections may be as high as 14%. peri-implantitis can limit clinical success and impose health and financial burdens to patients and health providers. the pathogenic species associated with periodontitis (e.g., fusobacterium ssp, a. actinomycetemcomitans, p. gingivalis) are also associated with peri-implantitis. incidence of peri-implantitis is highest within the first 12 months after implantatio ... | 2009 | 18698626 |
| fusobacterium necrophorum: a ruminal bacterium that invades liver to cause abscesses in cattle. | fusobacterium necrophorum, a gram-negative, rod-shaped, and an aerotolerant anaerobe, is a normal inhabitant of the rumen of cattle. the organism is in ruminal contents and adherent to the ruminal wall. its role in ruminal fermentation is to metabolize lactic acid and degrade feed and epithelial proteins. the ruminal concentration is higher in grain-fed than forage-fed cattle. from the rumen, the organism gains entry into the portal circulation and is trapped in the liver to cause abscesses. the ... | 2009 | 18595747 |
| orbital cellulitis and cavernous sinus thrombosis secondary to necrobacillosis. | 2009 | 18600243 | |
| lemierre's syndrome: methicillin-resistant staphylococcus aureus (mrsa) finds a new home. | lemierre's syndrome is septic thrombophlebitis of the internal jugular vein, arising as a complication of an oropharyngeal infection. this thrombophlebitis frequently results in septic emboli to organs such as the lungs. the causative agent in most previously described cases is fusobacterium necrophorum, an anaerobic gram-negative organism. we present the case of an 8-year-old previously healthy girl who came to the emergency department with a 5-day history of left-sided neck pain and was subseq ... | 2009 | 18280087 |
| clinical and microbiological determinants of ailing dental implants. | the failure of the host tissue to establish or maintain osseointegration around dental implants is due to either occlusal or parafunctional forces, premature loading, ill-directed stress, or microbial infection. the long-term failure rate of dental implants is generally 5-10%. although a variety of etiologies of early peri-implant bone loss (from implant placement to 1-year post-loading) have been proposed, factors associated with late implant failures are less well understood but are probably r ... | 2009 | 18384407 |
| photodynamic therapy as adjunct to non-surgical periodontal treatment in patients on periodontal maintenance: a randomized controlled clinical trial. | recent preclinical and clinical data have suggested the potential benefit of photodynamic therapy (pdt) in the treatment of periodontitis. however, currently, there are very limited data from controlled clinical trials evaluating the effect of pdt in the treatment of periodontitis. the aim of the present study was to evaluate the clinical and microbiological effects of the adjunctive use of pdt in non-surgical periodontal treatment in patients receiving supportive periodontal therapy. twenty-fou ... | 2009 | 18465191 |
| [acute mastoiditis in children: can mastoidectomy be avoided?]. | mastoidectomy is the standard management for exteriorized mastoiditis. the objective of this study was to assess the results of conservative management of acute mastoiditis and to study the types of bacteria isolated and their sensitivity to antibiotics. | 2009 | 19524875 |
| bacterial colonization of enamel in situ investigated using fluorescence in situ hybridization. | oral biofilms are one of the greatest challenges in dental research. the present study aimed to investigate initial bacterial colonization of enamel surfaces in situ using fluorescence in situ hybridization (fish) over a 12 h period. for this purpose, bovine enamel slabs were fixed on buccal sites of individual splints worn by six subjects for 2, 6 and 12 h to allow biofilm formation. specimens were processed for fish and evaluated with confocal laser-scanning microscopy, using probes for eubact ... | 2009 | 19528150 |
| epidemiology of pharyngeal carriage of fusobacterium necrophorum. | 2009 | 19528186 | |
| starvation response and growth in serum of fusobacterium nucleatum, peptostreptococcus anaerobius, prevotella intermedia, and pseudoramibacter alactolyticus. | the microbiota inhabiting the untreated root canal differ markedly from those found in post-treatment disease, yet there is limited information on the microbial characteristics distinguishing the different infections. we hypothesized that starvation survival is a key microbial property in species selection. this study analyzed starvation-survival behavior over 60 days of species representative of the untreated root canal infection: fusobacterium nucleatum, peptostreptococcus anaerobius, prevotel ... | 2009 | 19540450 |
| risk assessment of ciprofloxacin, flavomycin, olaquindox and colistin sulfate based on microbiological impact on human gut biota. | trace levels of veterinary antibiotics that reside in livestock products may disturb the balance of human intestinal microbiota and impair the colonized barrier function, which is critical to protect against the invasion or overgrowth of exogenous pathogens. we investigated the colonization barrier disruption effect of ciprofloxacin, flavomycin, olaquindox and colistin sulfate by the minimum inhibitory concentration (mic) assay in pure culture of human gut bacteria and evaluated the no-observed- ... | 2009 | 19545513 |
| lemierre's syndrome: a systematic review. | lemierre's syndrome is characterized by a history of recent oropharyngeal infection, clinical or radiological evidence of internal jugular vein thrombosis, and isolation of anaerobic pathogens, mainly fusobacterium necrophorum. it was once called the forgotten disease because of its rarity, but it may not be that uncommon after all. this review aims to provide physicians with an update on the etiology, management, and prognosis of lemierre's syndrome. | 2009 | 19554637 |
| a 21-year-old man with fever and abdominal pain after recent peritonsillar abscess drainage. | lemierre syndrome an extremely rare and unreported disease typically results from oropharyngeal infection and/or local tissue trauma with invasion of the parapharyngeal soft tissue with bacteria. once local tissue invasion occurs, internal jugular vein septic thrombophlebitis with or without metastatic complications may occur. the etiology of lemierre syndrome is generally fusobacterium necrophorum, reported to be present in approximately 80% of the cases. the outcome of lemierre syndrome in the ... | 2009 | 19555636 |
| bite-related and septic syndromes caused by cats and dogs. | bite infections can contain a mix of anaerobes and aerobes from the patient's skin and the animal's oral cavity, including species of pasteurella, streptococcus, fusobacterium, and capnocytophaga. domestic cat and dog bite wounds can produce substantial morbidity and often require specialised care techniques and specific antibiotic therapy. bite wounds can be complicated by sepsis. disseminated infections, particularly those caused by capnocytophaga canimorsus and pasteurella multocida, can lead ... | 2009 | 19555903 |
| real-time polymerase chain reaction to determine the prevalence and copy number of epstein-barr virus and cytomegalovirus dna in subgingival plaque at individual healthy and periodontal disease sites. | detection of cytomegalovirus (cmv) and epstein-barr virus (ebv) in plaque from patients with periodontal disease provides support for the theory that these viruses play a role in the pathogenesis of periodontitis. this study sought to further define this relationship by determining the prevalence of these viruses at individual disease and healthy sites of patients with periodontal disease and to determine whether the presence and amount of viral dna correlate with disease severity. | 2009 | 19563294 |
| fusobacterium nucleatum enters normal human oral fibroblasts in vitro. | fusobacterium nucleatum, a commensal opportunistic oral bacterium, is capable of invading gingival epithelial cells, but the entrance into human primary oral fibroblast cells has not been documented. this study evaluated the ability of three strains of f. nucleatum (f. nucleatum ssp. nucleatum, f. nucleatum ssp. polymorphum, and f. nucleatum ssp. vincentii) to enter gingival fibroblasts (gfs) and periodontal ligament fibroblasts (plfs). | 2009 | 19563299 |
| comparison between polymerase chain reaction-based and checkerboard dna hybridization techniques for microbial assessment of subgingival plaque samples. | to compare polymerase chain reaction (pcr) with subsequent reverse hybridization (micro-ident test) and checkerboard dna-dna hybridization for the identification of 13 bacterial species in subgingival plaque samples. | 2009 | 19563330 |