Publications

absence of detectable local antibody in genitourinary tract secretions of male contacts of women infected with trichomonas vaginalis.	samples of semen and urine were obtained from 37 male contacts of women with proved trichomonas vaginalis infection; on culture, eight (22%) of the men were shown to harbour the parasite. however, significant amounts of antitrichomonal antibody were found in only two of these samples, and the amounts present were very small. a further 10 samples were tested but none was found to contain antibody. the asymptomatic nature and low parasite numbers commonly described in infections in men is thus unl ...	1978	306858
[possibility of staining trichomonas vaginalis by acridine orange (author's transl)].		1978	151598
mepartricin, a polyene active on both trichomonas and candida. lack of mutagenic activity.	mepartricin, the methyl ester of partricin, is a new polyene antibiotic with antifungal and antiprotozoal activity. the antitrichomonas activity in vitro is comparable to that of metronidazole, the widely used drug recently demonstrated to possess mutagenic activity and thus to be used with caution in therapy. clinical investigations have shown that mepartricin can be successfully used in the topic treatment of vaginal trichomoniasis and candidiasis. the mutagenic activity of mepartricin has bee ...	1978	340260
biological assay of potential trichomonacides in vitro using a counter apparatus.	utilising the accuracy and speed of a coulter counter for cell counting and sizing, a new method of antimicrobial assay has been developed in which the potency of inhibitors is calculated on a mol/cell basis. a total of 72 potential trichomonacides were screened against trichomonas vaginalis and the ed50 value estimated for 27 of the most interesting and potent compounds. the ed50 value for metronidazole was a mean of 5.12 fmol/cell and only 6 compounds were more potent. after the nitroimidazole ...	1978	314804
post-menopausal vaginitis.	the organisms cultured from the vaginal swabs of 383 women over 50 years old with vaginal discharge were compared with those from 148 normal women of similar age attending a cytology clinic. the only significant difference was that yeasts were found in 20% and 6% of the two groups of women, respectively. it is therefore concluded that in post-menopausal women with vaginal discharge, the main microbiological requirement is for the diagnosis and treatment of yeast infection.	1978	207869
synthesis and biological activity of new 2-nitroimidazole derivatives.	in an earlier paper we described the synthesis and the antitrichomonas activity of 2-nitro-alpha,alpha,1-trimethyl-1h-imidazole-5-methanol (2). starting from this compound, several derivatives have been synthesized. among these, the phenyl carbonate 8 has been shown to possess activity equal to that of 2 and to be less toxic. this compound therefore is interesting in comparison with some antitrichomonas agents currently in use clinically. before undertaking an in-depth investigation, compound 8 ...	1978	211235
genital herpesvirus infection in women attending a venereal diseases clinic.	routine cervical viral cultures (and cultures from lesions if present) were performed on 2630 female patients attending a venereal diseases clinic over a period of four years. of these patients 96 (3.7%) had genital herpetic infection; of these 23 (24%) were asymptomatic. the association of herpesvirus with other genital infections is considered, but no increase in the incidence of neisseria gonorrhoeae, trichomonas vaginalis, and genital warts was found; there was an increased incidence of cand ...	1978	213162
relationship of herpes simplex virus type-2 antibodies and squamous dysplasia to cervical carcinoma in situ.	serum specimens from 75 women with cervical carcinoma in situ, 84 with squamous dysplasia, and 132 controls, who had previously been interviewed and tested for complement fixing antibodies against a number of organisms, were analyzed for hsv-2 antibodies. carcinoma in situ and severe dysplasia were associated with hsv-2 antibodies. mild dysplasia was related to evidence of prior infection by trichomonas vaginalis, adenoviruses, and mycoplasma pneumoniae, plus a history of vaginal discharge. seve ...	1978	215294
[study of the prostatic contents in the detection of asymptomatic trichomoniasis in men].		1978	307262
[trichomonas vaginalis].		1978	307485
risk of cervical cancer among an electrocoagulated population.	in finland an organized mass screening program covers the total female population. based on the material (429,832) from a nationwide mass screening registry it was estimated that the female population not subjected to electrocoagulation of the uterine cervix (362,511) had a sixfold risk of frankly invasive carcinoma, a fourfold risk of carcinoma in situ or dysplasia of high degree, and a twofold risk of dysplasia of low degree as compared with the female population subjected to electrocoagulatio ...	1978	307910
effect of oxygen and carbon dioxide on the growth of trichomonas vaginalis and tritrichomonas foetus.		1978	309937
[vagicult set for detection of trichomonas vaginalis and yeasts in vaginal smears].		1978	310116
evaluation of the indirect hemagglutination technique for study of trichomonas vaginalis infections, particularly in men.	the indirect hemagglutination (iha) technique was evaluated for use in the serologic study of infection with trichomonas vaginalis. the iha test showed that sera from 88% of women attending a venereal disease clinic had antibody to t. vaginalis. the antibody frequency and titers were highest in women who had documented infections due to t. vaginalis. serologic and cultural evidence of recent or active trichomonal infection was found in 11% of 85 men who had nongonococcal urethritis, but was abse ...	1978	310166
an electron microscopic investigation on the pathogenesis of human vaginal trichomoniasis.	the fine structure of trichomonas vaginalis and its acid phosphatase activity in the vaginal medium was investigated with the aid of the electron microscope. the relationship among trichomonads, desquamated epithelial cells, macrophages and bacteria was examined with special attention directed towards their phagocytic behavior. acid phosphatase activity was observed in the golgi apparatus, phagolysosomes and in the chromatic granules of trichomonas vaginalis. macrophages and leukocytes also exhi ...	1978	310614
lipid synthesis by trichomonas vaginalis.		1978	310661
isolation of trichomonas vaginalis resistant to metronidazole.		1978	80664
[round forms of trichomonas vaginalis. demonstration using vital staining and phase contrast. morphological differentiation in practice].		1978	84442
[personal prophylaxis of venereal diseases].		1978	97875
microbiology of the vagina in children: normal and potentially pathogenic organisms.	vaginal cultures from 100 healthy girls, 2 months to 15 years of age, were examined for the presence of normal and potentially pathogenic microorganisms. corynebacterium vaginale, yeast species, and genital mycoplasmas were isolated from vaginal cultures from 13.5 %, 28%, and 28% of the girls examined, respectively. colonization with these organisms was not associated with signs or symptoms of vaginitis. neisseria gonorrhoeae was isolated from a 4-year-old with purulent vaginitis. trichomonas va ...	1978	98750
[non-gonorrhoic urethritis caused by trichomonas vaginalis].		1978	101829
in vitro sensitivity of trichomonas vaginalis and candida albicans to chemotherapeutic agents.	strains of fresh clinical isolates of trichomonas vaginalis and candida albicans have been tested in vitro for their sensitivity to eight drugs used in the therapy of monilial and trichomonal vaginitis. three of the chemotherapeutic agents, chlorchinaldol, clotrimazole and broxyquinoline were effective against both organisms. tinidazole and metronidazole were active against t. vaginalis. the strains of c. albicans were also sensitive to trichomycin, natamycin and nystatin. tinidazole was the mos ...	1978	102108
chlamydia trachomatis cervicitis in gynecologic outpatients.	symptoms suggestive of a lower genital tract infection (lgti) are common complaints in women who consult gynecologists. sexually transmitted microorganisms, such as chlamydia trachomatis. neisseria gonorrhoeae, and trichomonas vaginalis, are responsible for a substantial proportion of lgti. this study was performed to establish the frequency of lgti caused by c trachomatis in women attending a gynecologic outpatient clinic. of 170 women with lgti, 32.9% harbored one or more of these organisms: c ...	1978	104212
vaginal discharge and sexually transmitted diseases.		1978	108216
activity-electroreduction relationship of antimicrobial metronidazole analogues.		1978	25969
[conference held in warsaw on 3rd april 1976 "standardization of methods of identification of t. vaginalis"].		1978	31733
duration of colposcopic changes associated with trichomonas vaginitis.	the possibility that an abnormal papanicolaou smear of the uterine cervix may be associated with vaginitis due to trichomonas vaginalis has been known for some time. since colposcopy is being used with increased frequency to evaluate patients with cytologic abnormalities noted on the cervical smear and the colposcopic changes produced by trichomonal vaginitis are quite typical, a study was designed to evaluate the duration of these changes after effective eradication of the parasite. among 12 pa ...	1978	619328
[the role of trichomonas vaginalis and fungal infections in urologic inflammatory diseases].		1978	353649
description of trichomonas vaginalis by m. a. donné.		1978	364686
[vaginal candidiasis].	three hundred and eighty eight patients from the out-patient service of the "10 de octubre" maternal-infantile hospital were studied and 126 (32,46%) out of them were infected with candida genus organisms. ninety nine (78,57%) patients had c. albicans; 16 (12,69%) patients had c. tropicalis; 9 (7,14%) patients had c. parakrusei; 1 (0,79%) patient had c. krusei; and 1 (0,79%) patient had c. guilliermondi. leukorrhea predominated in 42% of patients; vaginal pruritus predominated in 22%; and low ab ...	1978	368915
ureaplasma urealyticum (t-mycoplasma) in vaginal fluid and cervical mucus from fertile and infertile women.	ureaplasma urealyticum (t-mycoplasma) was isolated more frequently and in heavier growth from cervical mucus (49%) than from vaginal fluid (34%). it was isolated in 24% of vaginal fluid samples and in 35% of cervical mucus samples from fertile women, and in 29% of vaginal fluid samples and in 47% of cervical mucus samples from infertile women. the incidence of infection was high following abortion or total hysterectomy and during pregnancy or oral contraceptive use. t-mycoplasma was also isolate ...	1978	568567
[trichomonas vaginalis, a reservoir for retention of the gonococcus. the treatment of a mixed gonorrhea-trichomonas infection].		1978	418592
[the efficacy of established, systemically active trichomonacidal agents in the infection model tri-chomonas vaginalis/rat (author's transl)].	experimental chemotherapeutical studies were carried out with metronidazole, tinidazole, nitrimidazine and ornidazole in rats infected with trichomonas vaginalis intravaginally. all compounds tested showed a systemic trichomonacidal activity within rather a narrow dosage range after three oral doses and also after a single dose, i.e., 1.4-3.0 mg/kg and 7.7-15.9 mg/kg body weight (dc50), respectively.	1977	577434
an evaluation of tinidazole as single-dose therapy for the treatment of trichomonas vaginalis.	fifty patients suffering from trichomonas vaginalis infection were treated with a single dose of four 500 mg tablets of tinidazole; 41 patients returned for follow-up, and 39 of these were judged to be cured by the results of microscopic examination and culture of vaginal secretion.	1977	607115
a comparative study of trichomonas vaginalis prevalence in filipino women.	a comparative study of trichomonas vaginalis prevalence among filipino women is presented herein. a total of 288 women randomly drawn from various sources, including social hygiene clinics, health centers, and family planning centers in the metropolitan manila area were examined for t. vaginalis. nineteen or (6.8%) were found positive either by wet mount or stained smear methods. prevalence was significantly higher among the group of single than married women and five times higher among the wait ...	1977	607419
observations on trichomonas vaginalis infections in zambia.	microscopy and culture of high vaginal swabs from an ante-natal clinic showed that 38.5% of the women harboured trichomonas vaginalis; the corresponding figure from a gynaecology clinic was 31.4%. the incorporation of the culture method together with direct microscopy as a diagnostic technique in a routine laboratory is emphasized. urine microscopy in out-patients, in-patients and medical examinees indicates that t. vaginalis in both males and females is not a rare infestation but the prevalence ...	1977	562376
[trichomoniasis in the newborn (author's transl)].	trichomonas vaginalis was diagnosed in two girls out of 948 newborn babies (0.21%) admitted for various reasons to the universitäts-kinderklinik graz during a 21 months period. one of the patients revealed leukocyturia and vulvovaginitis, the other had both bacterial urinary tract infection and vulvovaginitis being controlled but incomplete with antibiotica therapy. the radiologic finding of the urinary tract were normal. in both cases trichomonas vaginalis was identified in a routine urine spec ...	1977	896250
an evaluation of trichomoniasis in two ethnic groups in papua new guinea.	different population groups in papua new guinea were examined for infestation with trichomonas vaginalis. melanesian women (44.6%) were more likely to be infected than caucasian women (14.2%). similarly, melanesian men (10.9%) had a higher prevalence of infection than caucasian men (0%). among the women, infection with t. vaginalis was also correlated with increasing age, parity, and place of residence.	1977	910202
an evaluation of cervical cytological screening in the university teaching hospital, lusaka.	a diagnostic cytology service was started in the obstetric and gynaecology department of university teaching hospital, lusaka in september, 1974. its primary aim was to diagnose precancerous lesions or early invasive cancer of the cervix. however, the service was offered to other disciplines in the hospital who could benefit from cytology. during the two and a half period, september 1974, to 31st december 1976, 2,877 cervical smears were examined. of these, 138 smears (4.8%) showed evidence of c ...	1977	919782
synthesis and biological activity of some vinyl-substituted 2-nitroimidazoles.	in previous studies 1-methyl-2-nitro-1h-imidazole-5-carboxaldehyde and 1-methyl-2-nitro-5-vinyl-1h-imidazole were found to posses interesting antimicrobial activities. we have now prepared some 2-nitro-1h-imidazoles in which the 5-vinyl chain bears selected functional groups (cho, coch3, no2) as well as nitrogen-condensation derivatives of the carbonyl functions. furthermore, 5-methyl-2-nitro-1-vinyl-1h-imidazole has been synthesized. all the compounds, and some intermediates, have been assayed ...	1977	16132
a study of the possible value of acridine orange-o strain in the diagnosis of trichomonas vaginalis infection.		1977	66993
[pictures of t. vaginalis obtained by a modified method of staining cytological preparations].		1977	75611
1,4-bis-[1-methyl-5-nitroimidazolyl-(2-methyleneimino)]-piperazine, a new drug with marked activity against entamoeba histolytica. short communication.	1,4-bis-[1-methyl-5-nitroimidazolyl-(2-methyleneimino)]-piperazine (hoe 316) administered orally produces an effect which is clearly superior to that of metronidazole against entamoeba histolytica in the golden hamster and slightly inferior against trichomonas fetus and t. vaginalis in the mouse. the acute tolerance of the compound is very good (ld 50% greater than 10 g/kg body weight). it is assumed that the possible main metabolite of hoe 316 is a monohydrazone: 1-methyl-2-(4-amino-piperazino- ...	1977	195590
microbiology of the female reproductive tract. v. changing patterns within one decade in a french canadian population.		1977	299891
additional uses of polyvinyl alcohol (pva) in the fixation and staining of parasitic protozoa.		1977	300520
[trichomoniasis. physiopathology and therapy].	based on many years' experience with trichomonas vaginalis the author comes to the conclusion that trichomonads are much more common than expected. therefore the possibility of trichomoniasis shoudl be taken into account not only when discharge is found in females or persistent urethritis in males, but also in other affections. remote reactions may occur in either sex, e.g. prostatis or adnexitis. sterility is sometimes due to trichomonas vaginalis. apart from classical pictures in either sex ar ...	1977	300704
comparisons between direct microscopic and cultural methods for recognition of corynebacterium vaginale in women with vaginitis.	the frequency with which clue cells could be detected in gram-stained vaginal smears and/or cervical papanicolaou (pap) smears was compared with the frequency of corynebacterium vaginale (haemophilus vaginalis) isolation in a group of 236 female patients, of whom 221 had vaginitis. vaginal clue cells were found most often in women from whom c. vaginale was isolated (p = 0.00006) whereas, conversely, clue cells in cervical pap smears were reported more frequently in women with negative cultures f ...	1977	300740
[trichomonas vaginalis in patients with non-gonorrheal inflammation of the urogenital tract and in healthy subjects].		1977	300889
[presence of trichomonas vaginalis in the urethra and bladder of women with colpitis trichomonalis].		1977	300992
comparative studies on the trichomonacidal activity of 5-nitroimidazole-derivatives in mice infected s.c. or intravaginally with t. vaginalis.	the trichomonacidal efficacy of metronidazole, tinidazole, nimorazole and ornidazole was studied in mice infected s.c., or for comparison purposes intravaginally. in both test systems, the drugs revealed nearly the same order of efficacy, whereby the compounds showed a marked decrease of activity when analyzed in s.c. infected mice.	1977	302218
[diagnosis of asymptomatic trichomonas vaginalis in men].		1977	302456
biological properties and clinical application of propolis. ii. studies on the antiprotozoan activity of ethanol extract of propolis.	solutions of the ethanol extract of propolis (eep) have shown a lethal effect on trichomonas vaginalis in vitro. similar lethal action was exhibited by eep after a 24-h contact with toxoplasma gondii.	1977	302709
[study of trichomonas vaginalis resistance to metronidazol spofa (author's transl)].		1977	302730
[trichomonas vaginalis incidence in the material of the hygiene centre of bratislava city (1970-1975) (author's transl)].		1977	302731
[isolation of trichomonas vaginalis].		1977	303171
interference of human spermatozoal motility by trichomonas vaginalis.	human spermatozoa were exposed to concentrations of live trichomonas vaginalis varying from 10(4) to 10(7) organisms per ml. a striking decrease in spermatozoal motility ensued. the possible role of trichomoniasis in human reproductive failure is considered.	1977	303705
[bacteriostatic, antimycotic and antitrichomonal effects in vitro of a new antineoplastic drug, ledakrin, polfa].		1977	303764
[trichomonas vaginalis and cytological findings (author's transl)].	the detection of trichomonas vaginalis by the method of the papanicolaou smear has proven as suitable. alterations of surface cells in the presence of trichomonas vaginalis are described, and causal relations between atypic cells and trichomonas vaginalis are discussed. from a total of 13000 in investigations of cancer screening in 1975, an infection with trichomonas vaginalis was found in 850 cases = 6,69 p.c. in contrast to this result 28 p.c. of the 116 patients with cancer of precancer of th ...	1977	303893
[some questions on the relationship between vaginal biocenosis and the course of pregnancy (proceedings)].		1977	304384
trichomonas vaginalis: effect of tinidazole on ultrastructure in vitro.		1977	304415
[morphological variability of t. vaginalis in vivo and in vitro].		1977	305158
[t. vaginalis donné variability in axenic cultures evaluated in scanning electron microscope].		1977	305159
[rosette and vegetative form of trichomonas vaginitis in women of the wrocław district and the wrocław district management of state railroads examined in the years 1973-1975].		1977	305160
[reproduction of vaginal trichomonas depending on the conditions of their habitat].		1977	305161
[penetration by t. vaginalis of female uterine cavity].		1977	305162
[effect on t. vaginalis of vaginal contents following electrocoagulation of the uterine neck].		1977	305163
[comparison of the population density of t. vaginalis donné in cultures with fungi strains isolated from cases of trichomonadosis or trichomonadosomycosis].		1977	305164
[behavior of the common part of the uterus in guinea pigs following infection with t. vaginalis. i. mast cells].		1977	305165
[diagnosis of trichomonas vaginitis by means of the carbonate agglutination reaction].		1977	305166
[effect of vaginal microorganisms on the epithelium of the vaginal part of the uterus].		1977	305167
[antitrichomonal action of new beta-diethylaminethyl acetophenone, isoxazole and chromanone ethers].		1977	305168
[in vitro effects of tinidazole on selected microorganisms of vaginal ontocenosis in trichomonas vaginitis].		1977	305169
microbes associated with leucorrhoea.		1977	305453
characteristics of some pathogenic fungi and trichomonas vaginalis donne in the scanning electron microscope.		1977	345751
synthesis and biological activity of two metabolites of 1-methyl-5-(1-methylethyl)-2-nitro-1 h-imidazole, an antiprotozoal agent.	5-(-hydroxyl-1-methylethyl-)-1-methyl-2-nitro-1 h-imidazole (6) and 5-(1,2-dihydroxyl-1-methylethyl)-1-methyl-2-nitro-1 h-imidazole (9) are the principal metabolites found in urines of animals (mice, rats, and dogs) treated with 1-methyl-5-(1-methylethyl)-2-nitro-1 h-imidazole (1), an effective antitrichomonas agent. these two metabolites have been synthesized. compound 6 was found to be less toxic than the parent compound 1 and to possess essentially the same activity against trichomonas vagina ...	1977	199729
immune response and degree of protection in mice immunized with trichomonas vaginalis antigen.	the immune response and degree of protection of mice immunized with t. vaginalis sonicated antigen injected by intraperitoneal route, intraperitoneal and intravaginal only has been studied. humoral response has been evaluated by indirect immunofluorescence and agglutination techniques; moreover, cytotoxicity of vaginal secreta has been investigated. cellular response has been evaluated by stimulation of peripheral lymph-node cells and spleen lymphocytes with t. vaginalis antigen. it has been obs ...	1977	306940
interrelationship of chlamydia trachomatis and other pathogens in the female genital tract.	the isolation of neisseria gonorrhoeae, chlamydia trachomatis, trichomonas vaginalis, and candida albicans in the female genital tract was studied in 1323 patients attending a venereal disease clinic. disruption of the cell monolayers use for the isolation of c. trachomatis was significantly associated with the presence of t. vaginalis; this effect was markedly reduced by the addition of vancomycin to gentamicin and amphotericin b in the transport and growth media. the only significant positive ...	1977	412875
[effect of t. vaginalis on the physiological vaginal flora].		1977	415437
ornidazole: a new antiprotozoal compound for treatment of trichomonas vaginalis infection.	a new anti-protozoal compound, ornidazole, a derivative of nitroimidazole, was given in a single 2 g dose to 20 women with trichomonas vaginalis infection. all the women were cured, but they suffered some side-effects. plasma levels of ornidazole reached a peak five to eight times higher than minimum inhibitory concentrations and exceeded this level for at least 36 hours. it is therefore possible that a smaller dose might have had an adequate trichomonicidal effect and fewer side-effects. furthe ...	1977	321095
single dose of two grams of metronidazole for trichomonas vaginalis infection.	in this study, 243 women with symptomatic trichomonal vaginitis were treated with eight 250 mg. tablets of metronidazole for themselves, and eight tablets were given to each of their male consorts. they were given instructions to ingest "all eight in a row" and "avoid alcohol for 48 hours." ninety-five per cent of 203 women that returned for re-examination were cured. this single-dose treatment is effective, well tolerated, and less expensive than current recommended dosages.	1977	324287
[in vitro action of mepartricin in combination with chlortetracycline].	the microbiological activity of a mepartricin + chlortetracycline hydrochloride association was evaluated on the principal agents causing cervico-vaginal infections. beside confirming the antimycotic and antiprotozoal efficacy of mepartricin, is was possible to demonstrate an absence of antagonism with chlortetracycline. on the other hand, in some cases this antibiotic could potentiate the antitrichomonas effect of mepartricin.	1977	324437
antibiotics produced by streptomyces olivaceus 142. ii. isolation, purification and activity spectrum of antibiotic wr 142-fpg.	a method of isolating antibiotic wr 142-fpg from the fermentation broth and mycelium of mutant fpg of the strain streptomyces olivaceus 142 has been developed. the method of purification of the active substance and activity spectrum agains microorganisms are described. some of the basic properties of two preparations are given: a) the preparation designed i, partly purified, containing a peptide moetye and b) the preparation designed ii, which is a homogeneous chromatographically preparation wit ...	1977	326221
comparison of ornidazole and tinidazole in single-dose treatment of trichomoniasis in women.	a comparison is made between oral ornidazole in a single 1-5 g dose and tinidazole given in a 2 g dose using a double-blind technique. all the 45 women with trichomonas vaginalis infection who were treated with ornidazole were cured. in the tinidazole-treated group 41 out of 43 women had negative cultures after treatment. tolerance was good in both groups.	1977	326349
[diagnosis of trichomonas vaginalis infestation in a fresh slide by the phase contrast microscopy (author's transl)].		1977	333419
n-substituted derivatives of em 49 structure-activity relationships.		1977	336594
current concepts of treating vaginitis.	vaginitis can be a frustrating entity to treat, since the incidence of recurrence is high. this paper examines evidence from the literature concerning diagnosis and treatment of candida albicans, trichomonas vaginalis, corynebacterium vaginale, herpes simplex type 2 and gonorrhea. a protocol based on these readings is outlined.	1977	21304797
[imidazoles in the treatment of infections due to parasitic protozoa "lumenals". (t. vaginalis, giardia intestinalis, e. histolytica--general principles)].		1976	196967
[infections transmitted in swimming pools].	public swimmingpools can be the source of infections due to micro-organism such as mycobacterium balnei, adeno and enteroviruses, the virus of plantar warts and molluscum contagiosum, the tric-agent of swimmingpool-conjonctivitis and pathogenic fungi. the transmission of trichomonas vaginalis is considered unlikely-water of pools, supposed to present satisfactory qualities by standard controls, was found to contain pathogenic staphylococci and pseudomonas aeruginosa. effective preventive measure ...	1976	186978
[pharmacologic study of the amebicidal and trichomonicidal activity of ornidazole (1-(2-hydroxy-3-chloropropyl)-2-methyl-5-nitroimidazole].		1976	188370
[study of the antiprotozoal activity of compounds of the series of diphenyl ethers and certain nitrostyrols].		1976	192989
comparison of four techniques for the routine diagnosis of trichomonas vaginalis infection.	specimens from 495 patients attending johannesburg hospitals and family planning clinics were examined for trichomonas vaginalis by microscopy of giemsa (gs), papanicolaou (pap), and acridine-orange (ao) stained smears, and by culture in feinberg-whittington medium. culture, pap and gs stained smears from vaginal swabs yielded fewer positives than ao stained smears. although pap-stained cytological smears gave the highest number of positives, in 30% of these cases the presence of t.vaginalis cou ...	1976	58872
the fine structure of cells of trichomonas vaginalis donné obtained from the exponential phase of growth and from stationary cultures.	in cells of trichomonas vaginalis in logarithmic phase of growth (log. t. vaginalis) the number of free cytoplasmic ribosomes was higher than that in cells from stationary cultures (stat. t. vaginalis). polyribosomes closely surrounding the chromatic granules were present in equal amounts in both categories fo cells, which indicates that they have specific functions and are not directly involved in the protein synthesis of the growing cell. the volume of the golgi region and of the food vacules ...	1976	60874
microbiology of the female genital tract during pregnancy and parturition.		1976	10196
tinidazole: a review of its antiprotozoal activity and therapeutic efficacy.	tinidazole, a synthetic imidazole derivative, has been used in the oral treatment of several protozoal infections - trichomoniasis, giardiasis and amoebiasis. among the protozoal organisms inhibited by tinidazole are trichomonas vaginalis, trichomonas foetus, and entamoeba histolytica. in vitro, tinidazole has been shown to possess antiprotozoal activity at least comparable to, and in some cases greater than, metronidazole. tinidazole also has activity against some gram-negative anaerobic bacill ...	1976	954609
[short-term treatment of trichomonas vaginalis infection with metronidazole (flagyl forte)].		1976	968874
corynebacterium vaginale (haemophilus vaginalis) in women with leukorrhea.	corynebacterium vaginale was recovered from vaginal-cervical swab specimens in 164 of 288 women with leukorrhea and in four of 30 women without signs or symptoms of lower genital tract infection. the amount and character of the leukorrhea observed in association with c. vaginale infection were variable; in typical cases the discharge had the appearance of a thin paste. in a series of 100 patients studied to determine the apparent causes of leukorrhea, noninfectious causes were inferred in seven ...	1976	984128
tinidazole (fasigyn)--single-dose therapy for trichomonas vaginalis.	in this open evaluation trial, tinidazole in a single dose of 2 g proved highly effective in the treatment of trichomonal vaginitis in 25 women. there were minimal side effects and patient acceptance was good.	1976	994982
[single oral administration of fasigyn in the treatment of genitourinary trichomoniasis].	in 35 women and 30 men with trichomoniasis one day therapy with fasigyn was applied. 8-th day after treatment trichomonas vaginalis was found in only three women and two men, but they were also curred by the repeated treatment. side effects were not observed. authors opinion is that this kind of therapy is specially acceptable in women with metrorhagia and those in preoperative care.	1976	1018507
[therapeutic trial of trichomonas vaginalis in male by using a single dose of tinidazole (author's transl)].		1976	786326
cervical bacterial flora in women fitted with a copper-releasing intra-uterine contraceptive device (iud).	a bacterial culture was taken from the cervix in 85 sexually active women before, and 3 and 6 months after, insertion of either a copper-releasing or an inert intra-uterine contraceptive device (iud). sixty had a copper-t (tcu-200) and 25 a lippes loop d. although in more than a quarter of the patients the bacterial flora increased slightly in diversity and abundance after iud insertion, there was no difference in effect between the tcu-200 and lippes loop d.	1976	788452