Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| reduced imipenem susceptibility in klebsiella pneumoniae clinical isolates with plasmid-mediated cmy-2 and dha-1 beta-lactamases co-mediated by porin loss. | we investigated the resistance mechanisms and clonality among 42 imipenem-non-susceptible klebsiella pneumoniae isolated at a tertiary care hospital in korea. two isolates had bla(vim-2) alleles, whereas bla(cmy-2)- and bla(dha-1)-like alleles were detected in 24 and 16 isolates, respectively, with these enzymes confirmed by sequencing for representative isolates. transfer of bla(cmy-2) and bla(dha-1) was achieved by conjugation. addition of 300 mg/l 3-aminophenylboronic acid (apb) reduced the m ... | 2007 | 17204406 |
| yersiniabactin is a virulence factor for klebsiella pneumoniae during pulmonary infection. | iron acquisition systems are essential for the in vivo growth of bacterial pathogens. despite the epidemiological importance of klebsiella pneumoniae, few experiments have examined the importance of siderophores in the pathogenesis of this species. a previously reported signature-tagged mutagenesis screen identified an attenuated strain that featured an insertional disruption in ybtq, which encodes a transporter for the siderophore yersiniabactin. we used this finding as a starting point to eval ... | 2007 | 17220312 |
| mosaic structure of p1658/97, a 125-kilobase plasmid harboring an active amplicon with the extended-spectrum beta-lactamase gene blashv-5. | escherichia coli isolates recovered from patients during a clonal outbreak in a warsaw, poland, hospital in 1997 produced different levels of an extended-spectrum beta-lactamase (esbl) of the shv type. the beta-lactamase hyperproduction correlated with the multiplication of esbl gene copies within a plasmid. here, we present the complete nucleotide sequence of plasmid p1658/97 carried by the isolates recovered during the outbreak. the plasmid is 125,491 bp and shows a mosaic structure in which a ... | 2007 | 17220406 |
| comparative in vitro killing of carbapenems and aztreonam against klebsiella pneumoniae producing vim-1 metallo-beta-lactamase. | 2007 | 17223016 | |
| is all free time above the minimum inhibitory concentration the same: implications for beta-lactam in vivo modelling. | previously, ertapenem 50 mg/kg every 6h given subcutaneously to mice achieved a similar 24-h cumulative free time above the minimum inhibitory concentration (ft>mic) to 1g every 24h in humans. however, this simplified regimen (sr) does not provide a superimposable concentration-time profile to that observed in humans, thus allowing concentrations to fluctuate above and below the minimum inhibitory concentration (mic) throughout the 24-h period. herein, we compared a complex regimen (cr; 9 variou ... | 2007 | 17223318 |
| synthesis and biological evaluation of new n-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. | a new series of n-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamide and phenylacetamide derivatives (1a-1n, 2a-2n) were synthesized and evaluated for antibacterial and antifungal activities against staphylococcus aureus, bacillus subtilis, klebsiella pneumoniae, pseudomonas aeruginosa, escherichia coli, candida albicans, and their drug-resistant isolate. microbiological results indicated that the compounds possessed a broad spectrum of activity against the tested microorganisms at mic values betwee ... | 2007 | 17223562 |
| emergence of arma and rmtb aminoglycoside resistance 16s rrna methylases in belgium. | 16s rrna methylase-mediated high-level resistance to aminoglycosides has been reported recently in clinical isolates of gram-negative bacilli only from a limited number of countries. this study was conducted to investigate the occurrence of this type of resistance in clinical isolates of enterobacteriaceae from two belgian hospitals and the characteristics of the strains. | 2007 | 17224412 |
| lipopolysaccharide o-antigen promotes persistent murine bacteremia. | bacteremia is a common complication of pneumonia with klebsiella pneumoniae. in the previous work, we have shown that the lipopolysaccharide (lps) o-antigen in k. pneumoniae o1:k2 contributes to lethality during pneumonia in part by promoting bacteremia. in the current work, we studied an o-antigen-deficient k. pneumoniae strain to further evaluate this polysaccharide's role in bloodstream infection. cultured macrophage and murine bacteremia models were studied. in vitro, o-antigen-deficient bac ... | 2007 | 17224794 |
| prevalence of extended-spectrum beta-lactamases-producing isolates over a 1-year period at a university hospital in oman. | to evaluate the prevalence of extended-spectrum beta-lactamases isolates over one year period at sultan qaboos university hospital. | 2007 | 17206284 |
| causes of nosocomial pneumonia and evaluation of risk factors in a university hospital in turkey. | to determine the incidence, risk factors, mortality rate, and organisms causing nosocomial pneumonia (np). | 2007 | 17206302 |
| sputum bacteriology in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease in taiwan with an emphasis on klebsiella pneumoniae and pseudomonas aeruginosa. | bacterial infection is one of the major causes of acute exacerbation of copd (aecopd). this study was undertaken to investigate the microbiology of aecopd. | 2007 | 17207030 |
| differences in the evolution of imipenem susceptibility among klebsiella pneumoniae and escherichia coli isolates during a 6-year period in a tertiary care hospital. | the evolution of imipenem disk-diffusion susceptibility results of 2652 strains of klebsiella pneumoniae and 7596 escherichia coli isolated during the period 2000-2005 were analysed. screening for production of metallo-beta-lactamases was performed using the edta-synergy method. the percentage rate of k. pneumoniae isolates having a zone diameter < or =25 mm increased from 20% in 2000 to 41% in 2005, whereas the respective rate of isolates having a zone diameter > or =30 mm decreased from 48 to ... | 2007 | 17207610 |
| high prevalence of shv-12 and the emergence of ctx-m-12 in clinical isolates of klebsiella pneumoniae from korea. | 2007 | 17227703 | |
| vim-1-producing klebsiella pneumoniae bloodstream infections: analysis of 28 cases. | 2007 | 17229554 | |
| in vitro activity of tigecycline against carbapenem-susceptible and -resistant isolates of klebsiella spp. and enterobacter spp. | 2007 | 17229831 | |
| bacterial counts in organic materials used as free-stall bedding following treatment with a commercial conditioner. | an acidic conditioner was tested in recycled manure and sawdust used as free-stall bedding to determine the effect on bacterial counts of common environmental mastitis pathogens. free stalls were bedded with 10 kg of either kiln-dried sawdust or recycled manure per stall. all bedding was removed and fresh bedding was applied every 7 d. approximately 1 kg of commercial bedding conditioner containing 93% sodium hydrosulfate (wt/wt) was spread evenly over bedding in the back one-third of each treat ... | 2007 | 17235185 |
| catheter associated infections in hemodialysis patients. | hemodialysis catheter related infections (hcri) are one of the major causes of increasing mortality, morbidity and cost of therapy in hemodialysis patients. prevention of hcri requires the identification of predisposing risk factors. to determine the frequency of hcri risk factors, we studied 116 patients (54% male, mean age of 49.5+/-16 years) patients with hcri between 2003-2004. forty one percent of the patients were diabetic. there was a history of previous catheter placement and infection i ... | 2007 | 17237890 |
| synthesis, stereochemistry and antimicrobial evaluation of t(3)-benzyl-r(2),c(6)-diarylpiperidin-4-one and its derivatives. | in a wide research program toward new and efficient antimicrobial agents, a series of t(3)-benzyl-r(2),c(6)-diarylpiperidin-4-ones (1-7) were synthesised and tested for their in vitro antibacterial and antifungal activities. also, the structures and their stereochemistry of these synthesised compounds 1-7 were characterized by ir, high resolution (1)h nmr, (13)c nmr and (1)h-(13)c cosy spectra. the analysis of coupling constants of compounds 1-5 reveals that they exist in normal chair conformati ... | 2007 | 17241703 |
| antimicrobial activity of long-chain, water-soluble, dendritic tricarboxylato amphiphiles. | to measure the antimicrobial activities of three series of homologous, dendritic tricarboxylato (three-headed) amphiphiles against a battery of bacteria and fungi. | 2007 | 17242037 |
| molecular characterization of extended-spectrum beta-lactamases in enterobacteriaceae from patients of two hospitals in saxony, germany. | between january and september 2003, 39 isolates of the family enterobacteriaceae with phenotypically positive vitek 1 extended-spectrum beta-lactamase (esbl) test results were collected, originating from patients of two hospitals in saxony, germany. plasmid dna was isolated and screened by pcr for the presence of genes encoding beta-lactamases of shv, tem and ctx-m types. to differentiate esbl and non-esbl among shv and tem genes, detailed analysis of pcr products was performed. twenty-four stra ... | 2007 | 17244807 |
| non-clostridial gas gangrene of the neck and mediastinum. | herein we report a case of gas gangrene of the neck and mediastinum in a poorly managed type ii diabetic with concomitant chronic renal failure and a recent history of mucormycosis. despite the burden of co-morbidities and the gravity of the illness, the patient was successfully treated and remained free of complications in the long term. | 2007 | 17244906 |
| changing trend of neonatal infection: experience at a newly established regional medical center in korea. | the purpose of the present paper was to study the natural history of neonatal sepsis in a newly established neonatal intensive care center that started in 1988 at gyeongsang national university hospital 9 (gnuh) in chinju city, korea. | 2007 | 17250501 |
| antimicrobial resistance patterns in enterobacteriaceae isolated from an urban wastewater treatment plant. | over 18 months, enterobacteria were isolated from the raw (189 isolates) and treated (156 isolates) wastewater of a municipal treatment plant. the isolates were identified as members of the genera escherichia (76%), shigella (7%), klebsiella (12%) and acinetobacter (4%). antimicrobial susceptibility phenotypes were determined using the agar diffusion method for the antibiotics amoxicillin, gentamicin, ciprofloxacin, sulfamethoxazole/trimethoprim, tetracycline and cephalothin, the disinfectants h ... | 2007 | 17250754 |
| characterization of klebsiella pneumoniae isolates from new zealand sea lion (phocarctos hookeri) pups during and after the epidemics on enderby island, auckland islands. | the 2001/2002 and 2002/2003 breeding seasons of new zealand sea lions (nzsls) on the auckland islands were marked by a high pup mortality caused by acute bacterial infections. as part of a health survey from 1998/1999 to 2004/2005, tissues and swabs of lesions had been collected at necropsy to identify the bacteria associated with pup mortality. klebsiella pneumoniae was grown in pure culture from 83% of various organs and lesions in 2001/2002 and 76% in 2002/2003, and less frequently in the fol ... | 2007 | 17250977 |
| antimicrobial resistance pattern among aerobic gram-negative bacilli of lower respiratory tract specimens of intensive care unit patients in a neurocentre. | analysis of the tracheal and bronchial isolates from the lower respiratory tract specimens of the intensive care unit (icu)-admitted patients, was carried out for the year 2002 with a perspective of looking at the antibiotic resistance pattern. | 2007 | 17256562 |
| first national surveillance of susceptibility of extended-spectrum beta-lactamase-producing escherichia coli and klebsiella spp. to antimicrobials in israel. | in this 1st national surveillance study, the susceptibility pattern of 1011 consecutive isolates of extended-spectrum beta-lactamase (esbl)-producing escherichia coli and klebsiella spp. isolated from patients hospitalized in israel hospitals, covering 62.3% of all general hospital beds in the country, was investigated. proportion of susceptibilities (range among institutions, mic(50)/mic(90) in micrograms per milliliter) were to ertapenem 95.0% (88.8-100%, 0.19/0.75), imipenem 98.8% (88.8-100%, ... | 2007 | 17258084 |
| complete degradation of dimethyl isophthalate requires the biochemical cooperation between klebsiella oxytoca sc and methylobacterium mesophilicum sr isolated from wetland sediment. | two bacterial strains klebsiella oxytoca sc and methylobacterium mesophilicum sr were isolated and identified from enrichment cultures using dimethyl isophthalate (dmi) as the sole source of carbon and energy, and mangrove sediment as an inoculum. dmi was rapidly transformed by k. oxytoca sc in the culture with formation of monomethyl isophthalate (mmi), which accumulated in the culture medium. m. mesophilicum sr, incapable of utilizing dmi, showed high capability of degrading mmi to a transitor ... | 2007 | 17258288 |
| [community-acquired urinary tract infections in 15 to 65 years old female patients in france. susceptibility of e. coli according to history: aforcopi-bio network 2003]. | a multicenter study was implemented in order to determine the distribution and antibiotic susceptibility patterns of strains isolated from 15 to 65 year old female patients with community-acquired urinary tract infections. | 2007 | 17258415 |
| computed tomographic differences of pyogenic liver abscesses caused by klebsiella pneumoniae and non-klebsiella pneumoniae. | to investigate the distinctive computed tomographic(ct) features of pyogenic liver abscess (pla) caused by klebsiella pneumoniae (kla). | 2007 | 17259834 |
| klebsiella oxytoca septicemia complicating rotavirus-associated acute diarrhea. | 2007 | 17259891 | |
| optimization of bio-hydrogen production from biodiesel wastes by klebsiella pneumoniae. | biodiesel wastes containing glycerol were utilized by klebsiella pneumoniae dsm 2026 to produce hydrogen. the optimization of medium components was performed using both plackett-burman and uniform design methods. using the plackett-burman design, glycerol, yeast extract, nh(4)cl, kcl and cacl2 were found to be the most important components, which were further investigated by uniform design and second-order polynomial stepwise regression analysis. the optimized medium containing 20.4 g.l(-1) glyc ... | 2007 | 17260330 |
| adsorption of olive leaf (olea europaea l.) antioxidants on silk fibroin. | the adsorption isotherms of oleuropein and rutin were evaluated at different temperatures, ph values, and solid/liquid ratios. the experimental data of adsorption isotherms were well fitted to a langmuir model. the maximum adsorption capacities were determined as 108 mg of oleuropein/g of silk fibroin and 21 mg of rutin/g of silk fibroin. after adsorption of oleuropein and rutin, the antioxidant capacity of silk fibroin increased from 1.93 to 3.61 mmol of teac/g. silk fibroin also gained antimic ... | 2007 | 17261014 |
| clinical variables associated with the isolation of klebsiella pneumoniae expressing different extended-spectrum beta-lactamases. | clinical variables associated with the isolation of klebsiella pneumoniae expressing different extended-spectrum beta-lactamases (esbls) were studied. clinical records of patients with esbl-positive k. pneumoniae isolates between 1989 and 2003 (n = 80) were reviewed retrospectively. patients with shv- and tem-type esbls were identified more frequently in the intensive care units (67% and 78%, respectively), whereas those with ctx-m esbls were found in medical wards (52.2%) or were outpatients (1 ... | 2007 | 17263834 |
| biofilm formation by multidrug-resistant salmonella enterica serotype typhimurium phage type dt104 and other pathogens. | the biofilm-forming capability of salmonella enterica serotypes typhimurium and heidelberg, pseudomonas aeruginosa, listeria monocytogenes, escherichia coli o157:h7, klebsiella pneumoniae, and acinetobacter baumannii isolated from humans, animal farms, and retail meat products was evaluated by using a microplate assay. the tested bacterial species showed interstrain variation in their capabilities to form biofilms. strong biofilm-forming strains of s. enterica serotypes, e. coli o157: h7, p. aer ... | 2007 | 17265855 |
| detection of bacteria in platelet concentrates prepared from spiked single donations using cultural and molecular genetic methods. | bacteria show differences in their growth kinetics depending on the type of blood component. on to storage at 22 degrees c, platelet concentrates (pcs) seem to be more prone to bacterial multiplication than red cell concentrates. knowledge of the potential for bacterial proliferation in blood components, which are stored at a range of temperatures, is essential before considering implementation of a detection strategy. the efficacy of bacterial detection was determined, using real-time reverse t ... | 2007 | 17266705 |
| membrane topology prediction by hydropathy profile alignment: membrane topology of the na(+)-glutamate transporter glts. | structural classification of families of membrane proteins by bioinformatics techniques has become a critical aspect of membrane protein research. we have proposed hydropathy profile alignment to identify structural homology between families of membrane proteins. here, we demonstrate experimentally that two families of secondary transporters, the ess and 2hct families, indeed share similar folds. members of the two families show highly similar hydropathy profiles but cannot be shown to be homolo ... | 2007 | 17269795 |
| neutrophil elastase depends on serglycin proteoglycan for localization in granules. | granule proteins play a major role in bacterial killing by neutrophils. serglycin proteoglycan, the major intracellular proteoglycan of hematopoietic cells, has been proposed to play a role in sorting and packing of granule proteins. we examined the content of major neutrophil granule proteins in serglycin knockout mice and found neutrophil elastase absent from mature neutrophils as shown by activity assay, western blotting, and immunocytochemistry, whereas neutrophil elastase mrna was present. ... | 2007 | 17272511 |
| hyperkalemia and cardiac arrest following succinylcholine administration in a 16-year-old boy with acute nonlymphoblastic leukemia and sepsis. | to report a case of potentially lethal hyperkalemia related to succinylcholine administration. | 2007 | 17273116 |
| evaluation of the growth inhibitory activities of triphala against common bacterial isolates from hiv infected patients. | the isolation of microbial agents less susceptible to regular antibiotics and the rising trend in the recovery rates of resistant bacteria highlights the need for newer alternative principles. triphala has been used in traditional medicine practice against certain diseases such as jaundice, fever, cough, eye diseases etc. in the present study phytochemical (phenolic, flavonoid and carotenoid) and antibacterial activities of aqueous and ethanol extracts of triphala and its individual components ( ... | 2007 | 17273983 |
| frequency of detection of periodontopathic and superinfecting bacteria in hiv-positive patients with periodontitis. | the aim of this investigation was to establish the frequency of detection of periodontopathic bacteria and gram-negative enteric rods in hiv-positive (hiv+) patients with periodontitis. | 2007 | 17274235 |
| effects of bacterial lipopolysaccharide on the pharmacokinetics of metformin in rats. | it was reported that the hepatic microsomal cytochrome p450 (cyp) 2c11, 2d1, and 3a1 (not via the cyp1a2, 2b1/2, and 2e1) were involved in the metabolism of metformin in rats. it was also reported that the expressions of cyp2c11 and 3a2 decreased in rats pretreated with klebsiella pneumoniae lipopolysaccharide (kplps). therefore, the pharmacokinetic parameters of metformin could be changed in rats pretreated with kplps. hence, the pharmacokinetic parameters of metformin were compared after both ... | 2007 | 17275228 |
| characterisation of plasmids encoding ctx-m-3 extended-spectrum beta-lactamase from enterobacteriaceae isolated at a university hospital in taiwan. | ctx-m-3 is the most common extended-spectrum beta-lactamase produced by enterobacteriaceae in taiwan. the present study was conducted to characterise the genetic environment surrounding bla(ctx-m-3). a total of 11 ceftriaxone-resistant isolates were studied: escherichia coli (n=4), klebsiella pneumoniae (n=5) and salmonella enterica serotypes anatum (sa831r) and potsdam (sc72). molecular methods used included polymerase chain reaction, sequencing, dna-dna hybridisation, conjugation, physical map ... | 2007 | 17275265 |
| nosocomial outbreak of genetically related imp-1 beta-lactamase-producing klebsiella pneumoniae in a general hospital in japan. | gram-negative bacteria with acquired metallo-beta-lactamase (mbl) resistance are being increasingly described worldwide. here we report the first case of an outbreak by a cluster of genetically related strains of klebsiella pneumoniae producing the imp-1 mbl. six isolates of k. pneumoniae with a ceftazidime minimum inhibitory concentration >/=64 microg/ml were collected between february 2003 and june 2004 in hanyu general hospital, saitama, japan. these isolates were analysed to establish the me ... | 2007 | 17276038 |
| differential expression of bla(shv) related to susceptibility to ampicillin in klebsiella pneumoniae. | klebsiella pneumoniae usually shows intrinsic resistance to ampicillin and other beta-lactams. bla(shv) is thought to be a key beta-lactamase gene responsible for this intrinsic resistance to ampicillin. nevertheless, surveys of clinical strains reveal that some isolates of k. pneumoniae that carry bla(shv) remain susceptible to ampicillin. to explore susceptibility to ampicillin in relation to bla(shv) in k. pneumoniae, we analysed the existence and transcription of bla(shv) and determined beta ... | 2007 | 17276039 |
| takotsubo cardiomyopathy associated with sepsis in type 2 diabetes mellitus. | 2007 | 17276831 | |
| inhibition of cyanide-insensitive respiration in klebsiella oxytoca sysu-011 by 8-hydroxyquinolone. | the inhibition of the cyanide (kcn)-insensitive respiration of klebsiella oxytoca sysu-011 by 8-hydroxyquinoline (8-hq) was determined. results showed that the profile of the rate of oxygen uptake of normal-grown and 8-hq-grown k. oxytoca sysu-011 was biphasic and similar, suggesting that 8-hq did not inhibit the respiration of normal-grown k. oxytoca sysu-011. a different biphasic kcn inhibition profile of respiration was observed for kcn-grown cells treated with and without 8-hq. no decrease i ... | 2007 | 17277908 |
| characterization of the proteins of bacterial strain isolated from contaminated site involved in heavy metal resistance--a proteomic approach. | the present study describes response of a bacterial strain isolated from a polluted river to heavy metal toxicity. the bacterium was identified to be klebsiella pneumoniae by biochemical tests using api 20e strips and 16s ribotyping. the isolate was studied for its tolerance to two heavy metals, i.e., cobalt (co(2+)) and lead (pb(2+)) by growing it in citrate mineral medium (cmm). proteomic approach involving two-dimensional polyacrylamide gel electrophoresis (2d page) and mass spectrometry (ms) ... | 2007 | 17210198 |
| emphysematous prostatitis caused by klebsiella pneumoniae. | emphysematous prostatitis is a rare condition that is characterized by gas and abscess accumulation in the prostate. we report a 60-year-old man with emphysematous prostatitis caused by klebsiella pneumoniae. he had a history of recently diagnosed diabetes mellitus and a 16-year history of alcoholic liver cirrhosis. he was admitted due to fever, dysuria and difficult urination. physical examination revealed lower abdominal tenderness and prostatic fluctuance on digital examination. leukocytosis, ... | 2007 | 17282974 |
| bactericidal activities of meropenem and ertapenem against extended-spectrum-beta-lactamase-producing escherichia coli and klebsiella pneumoniae in a neutropenic mouse thigh model. | the purpose of this study was to examine the in vivo efficacies of meropenem and ertapenem against extended-spectrum-beta-lactamase (esbl)-producing isolates with a wide range of mics. human-simulated dosing regimens in mice were designed to approximate the free drug percent time above the mic (ft>mic) observed for humans following meropenem at 1 g every 8 h and ertapenem at 1 g every 24 h. an in vivo neutropenic mouse thigh infection model was used to examine the bactericidal effects against 31 ... | 2007 | 17283197 |
| detection of extended-spectrum beta-lactamases among enterobacteriaceae by use of semiautomated microbiology systems and manual detection procedures. | three commercially available microbiology identification and susceptibility testing systems were compared with regard to their ability to detect extended-spectrum beta-lactamase (esbl) production in enterobacteriaceae, i.e., the phoenix automated microbiology system (bd diagnostic systems, sparks, md), the vitek 2 system (biomérieux, marcy l'etoile, france), and the microscan walkaway-96 system (dade behring, inc., west sacramento, ca), using routine testing panels. one hundred fifty putative es ... | 2007 | 17287329 |
| evaluation of the etest method for fosfomycin susceptibility of esbl-producing klebsiella pneumoniae. | 2007 | 17289760 | |
| comment on: occurrence, prevalence and genetic environment of ctx-m beta-lactamases in enterobacteriaceae from indian hospitals. | 2007 | 17289764 | |
| role of ceftazidime dose regimen on the selection of resistant enterobacter cloacae in the intestinal flora of rats treated for an experimental pulmonary infection. | the effect of ceftazidime dosing increments and frequency of dosing on the selection of ceftazidime-resistant enterobacter cloacae in the intestine was studied in rats, during treatment of a pulmonary infection caused by klebsiella pneumoniae. | 2007 | 17289765 |
| ertapenem resistance among klebsiella and enterobacter submitted in the uk to a reference laboratory. | the emergence of carbapenem resistance in enterobacteriaceae represents a major public health concern. we investigated ertapenem-resistant clinical isolates of klebsiella spp. and enterobacter spp. referred to the uk's national reference laboratory for antibiotic resistance. minimum inhibitory concentrations (mics) were determined and interpreted according to british society for antimicrobial chemotherapy guidelines. genes for carbapenemases and ctx-m extended-spectrum beta-lactamases (esbls) we ... | 2007 | 17293088 |
| in vitro antimicrobial activity of n-acetylcysteine against bacteria colonising central venous catheters. | 2007 | 17293092 | |
| effects of bacterial prey species and their concentration on growth of the amoebae acanthamoeba castellanii and hartmannella vermiformis. | two amoebae were presented with six bacterial prey at a range of concentrations, and the growth parameters of the amoebae were deduced. all but one bacterium (synechococcus) resulted in a positive growth response, but the gram-positive bacterium staphylococcus aureus proved to be difficult to digest and the heavily pigmented bacterium klebsiella ozaenae induced unusual amoebic behavior prior to ingestion. | 2007 | 17293529 |
| extended-spectrum and ampc beta-lactamases in escherichia coli and klebsiella pneumoniae from a rural south indian tertiary care hospital. | 2007 | 17296286 | |
| short communication: patterns of fecal shedding of klebsiella by dairy cows. | patterns and persistency of fecal shedding of klebsiella spp. by healthy adult dairy cattle were explored with probabilistic, statistical, and molecular methods. fecal shedding was monitored longitudinally in 92 animals in 1 herd for 5 mo. shedding patterns followed a random binomial distribution, and associations with host factors were not detected. for 12 animals from 4 herds, strain-typing of multiple fecal klebsiella isolates was performed by means of random-amplified polymorphic dna typing. ... | 2007 | 17297098 |
| the effect of amikacin and imipenem alone and in combination against an extended-spectrum beta-lactamase-producing klebsiella pneumoniae strain. | in vitro and in vivo activities of amikacin and imipenem alone, and in combination, were studied against an extended-spectrum beta-lactamase-producing klebsiella pneumoniae strain. the strain was in vitro susceptible to both antimicrobials at 10(5) and 10(7) cfu/ml. in time-kill studies amikacin, imipenem, and amikacin plus imipenem decreased the bacterial counts; difference between the bactericidal effects was not observed. chequerboard technique showed no interaction between the tested drugs. ... | 2007 | 17300908 |
| porin loss and ges-type extended-spectrum beta-lactamase primarily responsible for reduced susceptibility to imipenem. | 2007 | 17300909 | |
| detection of extended-spectrum beta-lactamases by using boronic acid as an ampc beta-lactamase inhibitor in clinical isolates of klebsiella spp. and escherichia coli. | we evaluated highly sensitive methods using boronic acid (ba) to detect extended-spectrum beta-lactamase (esbl) production. a total of 182 clinical isolates of klebsiella spp. (n = 118) and escherichia coli (n = 64) were analyzed: 62 harbored only esbls, 80 harbored both esbls and plasmid-mediated ampc beta-lactamases (pampcs), and 40 harbored only pampcs. the clsi confirmatory test detected all isolates that produce only esbls but detected 85% of isolates that produce both enzymes. when a >/=5- ... | 2007 | 17301276 |
| pandrug-resistant gram-negative bacteria: the dawn of the post-antibiotic era? | the evolving problem of antimicrobial resistance in pseudomonas aeruginosa, acinetobacter baumannii and klebsiella pneumoniae has led to the emergence of clinical isolates susceptible to only one class of antimicrobial agents and eventually to pandrug-resistant (pdr) isolates, i.e. resistant to all available antibiotics. we reviewed the available evidence from laboratory and clinical studies that reported on polymyxin-resistant and/or pdr p. aeruginosa, a. baumannii or k. pneumoniae clinical iso ... | 2007 | 17306965 |
| colistin-resistant isolates of klebsiella pneumoniae emerging in intensive care unit patients: first report of a multiclonal cluster. | infections due to multidrug-resistant (mdr) gram-negative pathogens in the icu have prompted the use of colistin, an antibiotic forgotten for decades. the aim of this retrospective observational study was to record and present the emergence of colistin-resistant klebsiella pneumoniae (crkb) in a greek icu. | 2007 | 17307769 |
| characterization of bacterial coliform occurrences in different zones of a drinking water distribution system. | to compare the bacterial coliforms detected from occurrences in three zones of a water distribution system supplied by two separate water sources. | 2007 | 17309620 |
| effect of ovotransferrin, protamine sulfate and edta combination on biofilm formation by catheter-associated bacteria. | to determine the effect of a composition comprising ovotransferrin (ot), protamine sulfate (ps) and ethylenediaminetetraacetic acid (edta) on biofilm formation by catheter-associated bacteria. | 2007 | 17309621 |
| association of hla-dqa1*03011-dqb1*0301 haplotype with the development of respiratory scleroma. | respiratory scleroma (rs) is a progressive, chronic, granulomatous disease caused by klebsiella rhinoscleromatis. there is only one report of rs association with hla-dq3. in this study, molecular association of hla class ii and rs was determined. | 2007 | 17321882 |
| relationship of antimicrobial control policies and hospital and infection control characteristics to antimicrobial resistance rates. | antibiotic misuse and noncompliance with infection control precautions have contributed to increasing levels of antimicrobial resistance in hospitals. | 2007 | 17322010 |
| hydrolytic resolution of (r,s)-2-hydroxycarboxylic acid esters in biphasic media: implication for rate-limiting formation or breakdown of tetrahedral intermediates in acylation step. | a thermally stable esterase (snsm-87) from klebsiella oxytoca is explored as an enantioselective biocatalyst for the hydrolytic resolution of (r,s)-2-hydroxycarboxylic acid esters in biphasic media, where the best methyl esters possessing the highest enantioselectivity and reactivity are selected and elucidated in terms of the structure-enantioselectivity correlations and substrate partitioning in the aqueous phase. with (r,s)-2-chloromandelates as the model substrates, an expanded michaelis-men ... | 2007 | 17323376 |
| antibacterial potency of methanol extracts of lower plants. | antibacterial potency of methanol extracts of three green lower plants, pneumatopteris afra, platycerium bifurcatum and nephrolepsis bisserata was determined using agar dilution method on clinical strains of escherichia coli, staphylococcus aureus, klebsiella spp. and salmomelia typhi. antibacterial activities were observed at concentrations of 12.5, 25.0, 50.0 and 100.0 microg/ml. their minimum inhibitory concentrations ranged from 12.5approximately 100 microg/ml. extracts of p. afra and p. bif ... | 2007 | 17323431 |
| pyogenic liver abscesses caused by klebsiella pneumoniae: us appearance and aspiration findings. | to retrospectively compare the ultrasonographic (us) appearance and amount of pus obtained at initial aspiration for liver abscesses caused by klebsiella pneumoniae with those for liver abscesses caused by other bacterial pathogens. | 2007 | 17325065 |
| screening of the antibacterial effects of a variety of essential oils on microorganisms responsible for respiratory infections. | the aim of this study was to examine the cytotoxicity and the antibacterial effects of a variety of essential oils on major respiratory tract pathogens. the cytotoxicity of 13 essential oils was evaluated on vero cells. the antibacterial activity was evaluated by the kirby bauer paper method, minimum inhibitory and bactericidal concentration against streptococcus pyogenes, agalactiae, pneumoniae and klebsiella pneumoniae, haemophilus influenzae, staphylococcus aureus and stenotrophomonas maltoph ... | 2007 | 17326042 |
| activity of imipenem against vim-1 metallo-beta-lactamase-producing klebsiella pneumoniae in the murine thigh infection model. | the in-vivo activity of imipenem against vim-1-producing klebsiella pneumoniae (vpkp) was assessed in a thigh infection model in neutropenic mice. animals were infected with three vpkp isolates (imipenem mics 2, 4 and 32 mg/l, respectively) and a susceptible clinical isolate (mic 0.125 mg/l) that did not produce any beta-lactamase with broad-spectrum activity. bacterial density at the site of infection was determined after imipenem treatment (30 and 60 mg/kg every 2 h for 24 h). the log(10) redu ... | 2007 | 17328735 |
| a dam methylation mutant of klebsiella pneumoniae is partially attenuated. | in klebsiella pneumoniae, a chromosomal insertion mutation was constructed in the dam gene, which encodes dna adenine methylase (dam), resulting in a mutant unable to methylate specific nucleotides. in some bacteria, the dam methylase has been shown to play an important role in virulence gene regulation as well as in methyl-directed mismatch repair and the regulation of replication initiation. disruption of the normal dam function by either eliminating or greatly increasing expression in several ... | 2007 | 17328745 |
| biodegradation of 4-chloroaniline by bacteria enriched from soil. | 4-chloroaniline has been released into the environment due to extensive use in chemical industries and intensive agriculture; hence, it becomes one of the hazardous pollutants in the priority pollutant list. in this study, three gram-negative bacteria were enriched and isolated from agricultural soil as 4-chloroaniline-degrading bacteria. they were identified as acinetobacter baumannii ca2, pseudomonas putida ca16 and klebsiella sp. ca17. they were able to utilize 4-chloroaniline as a sole carbo ... | 2007 | 17328747 |
| biochemical studies of klebsiella pneumoniae nifl reduction using reconstituted partial anaerobic respiratory chains of wolinella succinogenes. | in the diazotroph klebsiella pneumoniae the flavoprotein nifl inhibits the activity of the nif-specific transcriptional activator nifa in response to molecular oxygen and combined nitrogen. sequestration of reduced nifl to the cytoplasmic membrane under anaerobic and nitrogen-limited conditions impairs inhibition of cytoplasmic nifa by nifl. to analyze whether nifl is reduced by electrons directly derived from the reduced menaquinone pool, we studied nifl reduction using artificial membrane syst ... | 2007 | 17329251 |
| crystallization and preliminary x-ray characterization of 1,3-propanediol dehydrogenase from the human pathogen klebsiella pneumoniae. | 1,3-propanediol dehydrogenase (1,3-pd-dh), encoded by the dhat gene, is a key enzyme in the dissimilation process for converting glycerol to 1,3-propanediol in the human pathogen klebsiella pneumoniae. single colourless crystals were obtained from a recombinant preparation of 1,3-propanediol dehydrogenase overexpressed in escherichia coli. the crystals belong to space group p2(1), with unit-cell parameters a = 91.9, b = 226.6, c = 232.6 a, beta = 92.9 degrees. the crystals probably contain two d ... | 2007 | 17329826 |
| false susceptibility to cefotetan reported by microscan for dha-type ampc beta-lactamase-producing klebsiella pneumoniae. | this study evaluated the accuracy of cefotetan susceptibility determination using the microscan walkaway system for ampc-producing klebsiella pneumoniae. in total, 57 k. pneumoniae isolates that showed a d-shape flattening in a double-disk synergy test were studied. cefotetan mics were determined by the agar dilution method. the bla(dha) gene was detected in all 57 isolates, one of which co-harboured bla(cmy-1). according to the microscan system, 28 isolates were susceptible, 18 were intermediat ... | 2007 | 17331122 |
| clinical factors indicating the presence of pyogenic liver abscess in community-acquired klebsiella pneumoniae bacteremia. | 2007 | 17331777 | |
| prevalence & antimicrobial resistance pattern of extended spectrum beta-lactamase producing klebsiella spp isolated from cases of neonatal septicaemia. | extended spectrum beta-lactamase (esbl) producing klebsiella spp led to serious concern about septicaemic neonates in neonatal intensive care units (nicu) due to high resistance against commonly used antimicrobial agents. knowledge of disease burden and information on resistance to antimicrobials are required for proper management of such cases in nicus. here we report the prevalence and resistance pattern of esbl producing klebsiella spp isolated from cases of neonatal septicaemia at a tertiary ... | 2007 | 17332661 |
| microbiology of diabetic foot infections in a teaching hospital in malaysia: a retrospective study of 194 cases. | diabetes mellitus is a progressive disease with chronic complications. foot infections are a major complication of diabetes and eventually lead to development of gangrene and lower extremity amputation. the microbiological characteristics of diabetic foot infections have not been extensively studied in malaysia. this study investigated the microbiology of diabetic foot infections and their resistance to antibiotics in patients with diabetic foot infections treated at university of malaya medical ... | 2007 | 17332905 |
| resistance to gram-negative organisms due to high-level expression of plasmid-encoded ampc beta-lactamase blacmy-4 promoted by insertion sequence isecp1. | a klebsiella pneumoniae strain, ku6500, which showed resistance to extended-spectrum beta-lactams and produced the plasmid-encoded ampc beta-lactamase cmy-4, was identified from clinical isolates in japan. the aim of this study was to identify the mechanism of the high-level expression of blacmy-4. sequence analysis indicated that the promoter element of citrobacter freundii was conserved, but the insertion sequence isecp1 coding with the putative promoter element, was inserted into the ampr bin ... | 2007 | 17334724 |
| pyogenic liver abscess caused by klebsiella pneumoniae: analysis of the clinical characteristics and outcomes of 84 patients. | the increased incidence of pyogenic liver abscess caused by klebsiella pneumoniae (k.pneumoniae) was reported in the recent literature. this study was conducted retrospectively to investigate the clinical characteristics and outcomes of these patients. | 2007 | 17335656 |
| chronic nasal infection caused by klebsiella rhinoscleromatis or klebsiella ozaenae: two forgotten infectious diseases. | klebsiella rhinoscleromatis and klebsiella ozaenae are associated with chronic diseases of the upper airways: rhinoscleroma and ozena, respectively. these have become uncommon in developed countries. we report herein one case of each disease in patients living in marseilles, france, and include a review of the literature. | 2007 | 17337224 |
| imipenem-resistance in klebsiella pneumoniae in malaysia due to loss of ompk36 outer membrane protein coupled with ampc hyperproduction. | 2007 | 17337225 | |
| antibacterial activities of emblica officinalis and coriandrum sativum against gram negative urinary pathogens. | present investigation is focused on antibacterial potential of aqueous infusions and aqueous decoctions of emblica officinalis (amla) and coriandrum sativum (coriander) against 345 bacterial isolates belonging to 6 different genera of gram negative bacterial population isolated from urine specimens by employing well diffusion technique. aqueous infusion and decoction of emblica officinalis exhibited potent antibacterial activity against escherichia coli (270), klebsiella pneumoniae (51), k. ozae ... | 2007 | 17337425 |
| characterization of extended-host-range pseudo-t-even bacteriophage kpp95 isolated on klebsiella pneumoniae. | kpp95, isolated on klebsiella pneumoniae, is a bacteriophage with the morphology of t4-type phages and is capable of rapid lysis of host cells. its double-stranded genomic dna (ca. 175 kb, estimated by pulsed-field gel electrophoresis) can be cut only by restriction endonucleases with a cleavage site flanked either by a and t or by t, as tested, suggesting that it contains the modified derivative(s) of g and/or c. over 26 protein bands were visualized upon sodium dodecyl sulfate-polyacrylamide g ... | 2007 | 17337566 |
| [clinical and bacterial analysis of pediatric urinary tract infection]. | we analyzed the clinical and bacterial backgrounds of 120 patients with pediatric urinary tract infection (uti). escherichia coli was the main pathogen recovered from 98 patients (81.7%). all causative agents isolated from 50 uncomplicated uti cases were e. coli. of 98 cases of e. coli uti, 71 were treated with second-generation cephems, whose therapeutic effect was equal to that of third and fourth-generation cephems. mic50 and mic90 (microg/ml) for e. coli were as follows: cefazolin :2, 4; cef ... | 2007 | 17338310 |
| evaluation of endophytic colonization of citrus sinensis and catharanthus roseus seedlings by endophytic bacteria. | over the last few years, the endophytic bacterial community associated with citrus has been studied as an important component interacting with xylella fastidiosa, the causal agent of citrus variegated chlorosis (cvc). this bacterium may also colonize some model plants, such as catharanthus roseus and nicotiana clevelandii. in the present study, we compared the endophytic colonization of citrus sinensis and catharanthus roseus using the endophytic bacteria klebsiella pneumoniae. we chose an appro ... | 2007 | 17342049 |
| surveillance of antimicrobial susceptibility of urinary pathogens in a tertiary care hospital. | 2007 | 17342301 | |
| population pharmacokinetics and pharmacodynamics of cefpirome in critically ill patients against gram-negative bacteria. | to develop a population pharmacokinetics model for cefpirome in icu patients, to assess pharmacokinetic-pharmacodynamic profiles vs. mic distribution of likely icu pathogens, and to assess their expected cumulative fraction of response (cfr). | 2007 | 17342515 |
| detection and spread of escherichia coli possessing the plasmid-borne carbapenemase kpc-2 in brooklyn, new york. | a carbapenem-resistant isolate of escherichia coli was identified that possessed a 23-kb plasmid encoding klebsiella pneumoniae carbapenemase type 2 (kpc-2). a subsequent surveillance study involving hospitals in brooklyn, new york, revealed that, among 1417 e. coli isolates, 7 isolates (from 3 hospitals) possessed bla(kpc-2). e. coli possessing kpc-2 is emerging in our region, and improved methods for detection are urgently needed. | 2007 | 17342651 |
| prevalence and significance of a negative extended-spectrum beta-lactamase (esbl) confirmation test result after a positive esbl screening test result for isolates of escherichia coli and klebsiella pneumoniae: results from the sentry asia-pacific surveillance program. | a negative extended-spectrum beta-lactamase (esbl) confirmation test result obtained after a positive esbl screening test result using clinical and laboratory standards institute methods has been a common occurrence among isolates of escherichia coli and klebsiella pneumoniae in the sentry antimicrobial surveillance program in the asia-pacific region. among isolates collected between 1998 and 2004 this screen-positive, nonconfirmed profile (failed to show clavulanate synergy) was observed in 8.9 ... | 2007 | 17344367 |
| susceptibilities of esbl-producing enterobacteriaceae to ertapenem, meropenem and piperacillin-tazobactam with and without clavulanic acid. | faced with the extended-spectrum beta-lactamase (esbl) pandemic, we compared the susceptibilities of esbl-producing enterobacteriaceae to ertapenem, meropenem and piperacillin-tazobactam with and without clavulanate. | 2007 | 17347564 |
| salvage treatment of pneumonia and initial treatment of tracheobronchitis caused by multidrug-resistant gram-negative bacilli with inhaled polymyxin b. | systemic colistin has shown efficacy against multidrug-resistant pseudomonas aeruginosa and acinetobacter spp., but it has presented poor results in pneumonia. aerosolized polymyxin in cystic fibrosis patients has had good results. in this study, inhaled polymyxin b was used to treat respiratory infections by multidrug-resistant gram-negative bacilli (mr-gnbs). nineteen patients were treated with inhaled polymyxin b: 14 pneumonia, most of which had previously failed treatment with intravenous po ... | 2007 | 17350201 |
| reevaluation of current susceptibility breakpoints for gram-negative rods based on pharmacodynamic assessment. | although pharmacodynamic (pd) modeling is now being considered for decision support for susceptibility breakpoint determination against gram-negative bacteria, these pd-derived breakpoints should be verified using a clinically applicable population of organisms. in this analysis, a 5000-patient monte carlo simulation was used to determine pd breakpoints, the highest 2-fold mic in which the probability of bactericidal target attainment (pta) remained > or = 90%. percent susceptibilities for 639 p ... | 2007 | 17350206 |
| biodiversity of chloramphenicol-resistant mesophilic heterotrophs from southeast asian aquaculture environments. | in the present study, samples of pond water, sediment and farmed species were collected at 12 fish and shrimp farms in malaysia, thailand and vietnam to determine the biodiversity and environmental distribution of chloramphenicol-resistant (cmr) mesophilic heterotrophs in southeast asian aquaculture sites. following isolation on iso-sensitest agar supplemented with 35mug ml(-1) cm and dereplication using (gtg)(5)-pcr fingerprinting, 557 genotypically unique cmr strains were subjected to polyphas ... | 2007 | 17350231 |
| microbiological profile of septic complication in patients with cardiogenic shock following acute myocardial infarction (from the shock study). | we sought to assess the microbiologic profile of patients with suspected sepsis who participated in the should we emergently revascularize occluded coronaries in cardiogenic shock? (shock) trial, a randomized controlled trial of early coronary revascularization in patients with cardiogenic shock complicating acute myocardial infarction. a protocol-mandated sepsis form was completed prospectively for 54 patients (18%) with fever or leukocytosis suggestive of sepsis. these patients were divided fu ... | 2007 | 17350369 |
| surveillance of extended-spectrum beta-lactamase-producing bacteria and routine use of contact isolation: experience from a three-year period. | the usefulness and applicability of isolation precautions were questioned for extended-spectrum beta-lactamase (esbl)-producing strains of enterobacteriaceae in the endemic setting. we performed a surveillance programme for esbl-positive organisms and the infection control management of patients colonized or infected with these organisms. between 1 january 2002 and 31 december 2004, a total of 147 cases of esbl-producing strains of escherichia coli, klebsiella pneumoniae and proteus mirabilis fr ... | 2007 | 17350720 |
| fluvastatin ameliorates endotoxin induced multiple organ failure in conscious rats. | sepsis is a severe inflammatory disorder that may lead to multiple organ failure. lipopolysaccharide (lps) is associated with gram-negative sepsis and can activate monocytes and macrophages to release pro-inflammatory mediators such as tumor necrosis factor-alpha (tnf-alpha), nitric oxide (no) and anti-inflammatory mediator such as interleukin-10 (il-10). in this present study, we used fluvastatin, a hmg-coa reductase inhibitor, to study its effects upon lps-induced endotoxic shock in conscious ... | 2007 | 17353078 |
| activity of faropenem against cephalosporin-resistant enterobacteriaceae. | there is a need for new oral agents active against extended-spectrum beta-lactamase (esbl) producers, as these increasingly cause community-onset infections. we therefore evaluated faropenem, a penem in phase iii development, against recently collected oxyimino-cephalosporin-resistant bacteria. | 2007 | 17353220 |