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glucose counterregulation in diabetic autonomic neuropathy. 20072870835
glucose counterregulation in diabetic autonomic neuropathy. 20072870835
indirect fertility analysis in painters exposed to ethylene glycol ethers: sensitivity and specificity.semen analysis has proven useful in the clinical diagnosis of infertility and is the most widely used method of monitoring the effects of occupational exposure on male fertility. collection and analysis of semen samples in a field setting, however, require a highly motivated population and excellent technical resources, limiting the widespread application of the method. techniques of monitoring male worker fertility using questionnaires to avoid some of the difficulties of semen analysis have be ...20071951370
new serologic tests for early detection of coccidioidomycosis.arizona college students suspected of having recently acquired coccidioidomycosis were tested for anticoccidioidal antibodies and circulating fungal antigens using conventional antibody detection methods and new elisa procedures. of 233 patients with compatible symptoms, 26 had anticoccidioidal antibodies detected by conventional tests. elisa detected antibodies in sera from 20 of these patients and also from another 25 patients. patients with antibodies detected by either conventional or elisa ...20071899877
family structure and child health. 20071951818
respiratory-related recruitment of the masseter: response to hypercapnia and loading.to test the hypothesis that a muscle that closes the jaw, the masseter, can be recruited by ventilatory stimuli, we studied the electromyographic activation of the masseter and genioglossus in seven normal awake males who were exposed in random order to progressive hyperoxic hypercapnia, inspiratory threshold loading (-40 cmh2o), and combined hypercapnia and loading. with hypercapnia, the masseter was generally recruited after the genioglossus had been activated. once recruited, activation of bo ...20071885444
relation between airway responsiveness and serum ige in children with asthma and in apparently normal children.although asthma diagnosed by a physician is known to be related to serum ige levels, it is not known whether there is a relation between the level of ige and airway hyperresponsiveness to a methacholine challenge. the characteristics of asymptomatic persons that predispose them to airway hyperresponsiveness are also unknown.20071891008
[hemoptysis disclosing a plasma cell granuloma with intra-bronchial involvement].the authors report a case of a plasma cell granuloma in a young woman of 19 with a past history of congenital rubella, presenting with repeated small haemoptyses related to a pedunculated endo-bronchial tumour. the diagnosis was only made per-operatively, permitting an effective excision.20071857820
lymphokines in asthma: are they there and can they be detected? 20071913262
[mr tomography of aneurysmal bone cyst].the preoperative findings of magnetic resonance imaging (mri) in six histology-proven aneurysmal bone cysts (abc) are examined and compared with previous publications concerning mri of abc. the signal intensities differ considerably, and not all of our cases conform with the literature data. they can be summarised in three different subheadings: one form that is very inhomogeneous in t1- and t2-weighting, with fluid-fluid levels in the cystic spaces; one intermediate form without fluid-fluid lev ...20071932722
inner city psychiatry. 20071932958
synthesis and purification of radioactive fatty acylcarnitines of high specific activity.micromole quantities of radiolabeled fatty acylcarnitines of high specific activity were synthesized by a simple one-step, one-pot acylation of [3h]carnitine in the presence of the respective fatty acid and acid chloride. the acylated product was isolated in high yield and high purity using liquid-liquid partitioning with isopropanol:hydrochloric acid:heptane (4:1:12 v/v) followed by butanol extraction. product recovery was 91% for octanoyl[3h]carnitine and 90% for palmitoyl[3h]carnitine and con ...20071952050
the right to remain psychotic. 20071913407
autokinetic illusion as affected by suggestions of experimenter and observer.two experiments were done to examine whether an experimenter's suggestion and self-suggestion could affect the autokinetic illusion and to specify that effect. exp. i compared the effect of a facilitative suggestion with a suppressive one, by measuring the moving latency, duration, frequency, and by analyzing the movement trace. time and frequency did not detect any effects of marked individual differences. trace analysis, on the other hand, showed that suggestions were effective in the expected ...20071852560
effectiveness of fortnightly tooth brushing with amine fluorides in caries-prone subjects.the aim of this study was to assess the caries incidence and plaque accumulation in schoolchildren at caries risk, after brushing the teeth fortnightly with gels containing 0, 0.4% f, 1.25% f as amine fluoride (amf) or the common amine fluoride toothpaste containing 0.125% f. the study was conducted double blind over an 18-month period, and after 6 months discontinuation of brushing. only the group that brushed with the 1.25% amf gel showed a significant decrease in caries development compared t ...20071890532
[infectious endocarditis]. 20071855806
glucagon and clonidine testing in the diagnosis of pheochromocytoma.we assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor. in the glucagon stimulation test, blood was sampled 2 minutes after intravenous injection of 0.28 mumol (1 mg) glucagon, and in the clonidine suppression test, blood was sampled 3 hours after administration of oral clonidine, 1.30 mumol (0.3 mg)/70 kg body wt. baseline levels of catechols in antecu ...20072045133
an analysis of the acog and aap ethics statements on conflicts in maternal-fetal care. 20071932792
tissue integration of a12o3-ceramic dental implants (frialit)--a case report.the tissue intraosseous integration of a12o3-ceramic dental implants (frialit) is studied in a patient case, where an implant-fracture made it necessary to remove the implant from a patient's jaw. the surgical removing of the apical part of the implant with the use of a trepan bur made it possible to examine and visualize histologically and microradiographically the tissue adjacent to the implant. the results of both the histological and microradiographical studies showed that a good healing and ...20072374995
orthodontic graduate education survey--1983 to 1989. 20071951200
severe earache following nitrous oxide anaesthesia. 20071952025
hypothyroidism following combined treatment for hypopharyngeal and laryngeal carcinoma.the development of hypothyroidism following combined treatment for pharyngeal and laryngeal cancer has received little attention in the literature. we prospectively studied 32 patients over 4 years to determine the incidence of such hypothyroidism and to examine the effect of hemithyroidectomy associated with a combined treatment modality. all patients were men with pharyngeal or laryngeal squamous cell carcinomas and no prior history of thyroid disease. treatment consisted of radical surgery (3 ...20071951886
the significance of squamous differentiation in endometrial carcinoma. data from a gynecologic oncology group study.squamous differentiation is identified in about 25% of endometrial adenocarcinomas (ac). its significance has been the subject of debate for decades, and it has been reported that the prognosis of adenoacanthoma (aa) is better than, the same as, and worse than that of ac. part of this confusion has resulted from semantic differences relating to the use of aa and adenosquamous carcinoma (as). to investigate the prognostic importance of squamous differentiation in endometrial carcinomas and compar ...20071913465
prostatic cancer: where do we go from here?this paper focuses on advances in prostatic cancer that occurred during the past year. specific areas reviewed here are screening, radical surgery, locoregional disease, the no-therapy option, androgen-ablative therapy, prognostic factors, bone-specific therapy, hormone refractory disease, and prostate cancer biology.20071892925
[successful therapy of acute post-traumatic hepatic insufficiency using massive doses of corticosteroids]. 20072800168
depression in the elderly. characteristics and clinical management.major depression and clinically significant depressive symptoms occur commonly in the community-dwelling, medically ill, and institutionalized elderly. both major depression and depressive symptoms need thorough evaluation and treatment because of the significant morbidity and mortality associated with these syndromes. depression may be difficult to diagnose, especially in the medically ill elderly, because of the masking of depressive symptoms by somatic complaints or the presumption that sympt ...20071891394
perfusion characteristics of hepatic cavernous hemangioma using intravenous ct angiography (ivcta).thirty-three patients with 35 proven hepatic cavernous hemangiomas (hch) were studied with intravenous ct angiography (ivcta). 15 scans were performed during the first 30 s after bolus (6 ml/s) injection of 50 ml iodinated contrast material. thereafter 2 scans/min were obtained up to 30 min. three criteria were utilized at ivcta to make a specific diagnosis of hch: (1) detection of an intense mural nodular enhancement in the arterial phase. the density in the nodular region(s) should have a dens ...20071855518
[a method for the formalized assessment of neurotic manifestations].a method of estimation of the level of neurotization and psychopathization modified and tried by the author is described. four scales are distinguished: asthenias, depressions, anxieties and hypochondrias. based on a statistical evaluation of the results of examining 152 patients with neurasthenia and 82 normal persons criteria for differentiating between the clinical and subclinical levels of neurotization have been derived.20072168636
[the intradermal tuberculin test and the kveim-siltzbach test in sarcoidosis]. 20072223733
[the intradermal tuberculin test and the kveim-siltzbach test in sarcoidosis]. 20072223733
age, sex, and region adjusted concentrations of chromium and nickel in lung tissue.chromium (cr) and nickel (ni) concentrations were measured in lung tissue from 110 random necropsies by means of atomic absorption spectrometry. the subjects originated from the ruhr district (bochum (71 cases) and dortmund (16 cases) areas), which has been defined as a particular pollution area with locally high cr and ni emissions, and from münster and vicinity (23 cases). the cr and ni concentrations in lung tissue of the subjects from the ruhr district (3.09 (sd 2.99) micrograms cr/g, 0.65 ( ...20072223660
age, sex, and region adjusted concentrations of chromium and nickel in lung tissue.chromium (cr) and nickel (ni) concentrations were measured in lung tissue from 110 random necropsies by means of atomic absorption spectrometry. the subjects originated from the ruhr district (bochum (71 cases) and dortmund (16 cases) areas), which has been defined as a particular pollution area with locally high cr and ni emissions, and from münster and vicinity (23 cases). the cr and ni concentrations in lung tissue of the subjects from the ruhr district (3.09 (sd 2.99) micrograms cr/g, 0.65 ( ...20072223660
induction from a single instance: formation of a novel category.this study examines whether preschoolers can use information from a known category to induce a characteristic attribute of a novel, contrasting category based on a single instance. we showed 32 four-year-olds three instances of a given category and one instance of a target category. these objects could vary along two attribute dimensions, such as color and shape. all instances of the given category shared identical values of one attribute (e.g., all were blue), but could have different values of ...20072258687
induction from a single instance: formation of a novel category.this study examines whether preschoolers can use information from a known category to induce a characteristic attribute of a novel, contrasting category based on a single instance. we showed 32 four-year-olds three instances of a given category and one instance of a target category. these objects could vary along two attribute dimensions, such as color and shape. all instances of the given category shared identical values of one attribute (e.g., all were blue), but could have different values of ...20072258687
intrathecal administration of 131i radiolabelled monoclonal antibody as a treatment for neoplastic meningitis.fifteen patients with neoplastic meningitis received a single intrathecal injection of between 11 and 60 mci of a 131i radiolabelled monoclonal antibody (moab), chosen for its immunoreactivity to tumour. major toxicity was manifest as nausea, vomiting and headache (7/15 patients), reversible bone marrow suppression (3/8 patients) and seizures (2/15 patients). nine patients were evaluable for either a tumour or clinical response. six of these demonstrated an event-free response that was maintaine ...20072223581
intrathecal administration of 131i radiolabelled monoclonal antibody as a treatment for neoplastic meningitis.fifteen patients with neoplastic meningitis received a single intrathecal injection of between 11 and 60 mci of a 131i radiolabelled monoclonal antibody (moab), chosen for its immunoreactivity to tumour. major toxicity was manifest as nausea, vomiting and headache (7/15 patients), reversible bone marrow suppression (3/8 patients) and seizures (2/15 patients). nine patients were evaluable for either a tumour or clinical response. six of these demonstrated an event-free response that was maintaine ...20072223581
the increasing supply of physicians in us urban and rural areas, 1975 to 1988.despite the rapid growth of the us physician supply since the mid-1970s, it remains unclear whether physicians have spread into the most rural areas of the country. this report examines the urban-rural distribution of physicians between 1975 and 1988.20071951824
the beneficial effect of cyclosporine preloading in renal transplants from hla-haploidentical living donors. 20071989137
the diagnostic accuracy of rapid dipstick tests to predict urinary tract infection.this study summarizes the diagnostic accuracy data for dipstick nitrite and/or leukocyte esterase tests (the index tests) as predictors of bacterial urinary tract infection as defined by quantitative culture (the reference test). on-line search of the literature using the medlars database identified 1,017 citations, 51 of which were relevant and contained sufficient data for further analysis. from each citation, 2 x 2 tables of true-positive, true-negative, false-positive, and false-negative res ...20071951183
herniation of rae tube through split boyle davis gag. 20072268034
herniation of rae tube through split boyle davis gag. 20072268034
[a case of paroxysmal ventricular tachycardia surgically treated based on electrophysiological diagnosis].there was presented a case of recurrent ventricular tachycardia in the patient after myocardial infarction. considering uneffective pharmacotherapy and several cardiac arrests, the patient underwent guided endo-cardiotomy based on complex electrophysiological diagnostics (including intraoperative examination). postoperative period was uncomplicated. there were no recurrences of ventricular tachycardia during 18-month follow-up.20072082073
cough threshold to citric acid in diabetic patients with and without autonomic neuropathy.the cough reflex has been investigated in insulin dependent diabetic patients with and without autonomic neuropathy. the cough response to inhaled citric acid was determined in eight patients with diabetes who had severe autonomic neuropathy and compared with that in 10 who had no evidence of neuropathy. the patients with autonomic neuropathy had a higher median threshold for the cough response to citric acid (median 50%, range 20- greater than 100%) than non-neuropathic control patients (median ...20073212754
cough threshold to citric acid in diabetic patients with and without autonomic neuropathy.the cough reflex has been investigated in insulin dependent diabetic patients with and without autonomic neuropathy. the cough response to inhaled citric acid was determined in eight patients with diabetes who had severe autonomic neuropathy and compared with that in 10 who had no evidence of neuropathy. the patients with autonomic neuropathy had a higher median threshold for the cough response to citric acid (median 50%, range 20- greater than 100%) than non-neuropathic control patients (median ...20073212754
white cell counting in red cells and platelets: how few can we count? 20072360229
chorionic villus sampling for prenatal diagnosis in wales using dna probes--5 years' experience.chorionic villi were sampled from 125 women who requested prenatal diagnosis, either for genetic disorder or because of advanced maternal age. of these, 105 samples were obtained by the transcervical route and 20 were obtained by the transabdominal approach. the sampling success rate was 97 per cent (122/125). the mean maternal age of the patients was 31 years (range 17-44) and the mean gestational age at which the chorionic villus sampling was performed was 10 weeks (range 7-13 weeks). seventy- ...20072267238
special issue on behavioral pharmacology. 20071955809
[intubation of cadavers in medical training]. 20071948930
raising health care capital through the public equity markets. 20071949002
echocardiographic determination of aortic and pulmonary valve areas in subjects with normal hearts.two-dimensional and doppler echocardiography were performed in 70 subjects (aged 1 day to 16 years, body surface area from 0.08 to 2.1 m2) to determine aortic and pulmonary valve areas in normal children and adolescents. valve areas were determined by the continuity equation using echo-determined ventricular outflow tract diameters and doppler-determined flow velocities from the outflow tracts and corresponding great arteries. left ventricular outflow tract diameter ranged from 0.3 to 2.2 cm and ...20071892085
reliability of prognostic models in malignant melanoma. a 10-year follow-up study.certain histologic and clinical features of malignant melanoma have been shown to be indicators of prognosis, both collectively and individually. even though the predictive value of these features is well established, long-term survival is occasionally seen in individuals with multiple poor prognostic factors. to further examine this phenomenon, histologic sections from 53 patients with malignant melanoma excised between the years 1977 and 1980 in whom reliable clinical follow-up data were obtai ...20071951981
from the centers for disease control. eosinophilia-myalgia syndrome--new mexico. 20072810660
class i and class ii major histocompatibility complex antigens on hepatocytes: importance of the method of detection and expression in histologically normal and diseased livers.methodological differences in major histocompatibility complex (mhc) antigen detection were investigated on isolated, viable hepatocytes and cryostat hepatic sections from 27 children with liver disorders, six of whom had normal histology. class i antigens were constantly found on sections using a three step immunoperoxidase technique after acetone/chloroform fixation, other techniques being less sensitive, or on isolated hepatocytes by indirect immunofluorescence alone. with mechanical isolatio ...20071864983
comparison of within-group variabilities across older and younger adults: a meta-analysis.the hypothesis that individual differences in performance scores increase with increasing adult age was reviewed. a meta-analysis of memory articles appearing in the journal of gerontology from 1985 to 1990 was conducted to examine potential age differences in within-group variabilities. there was no strong evidence in the data reported here that overall younger adults are consistently more alike in their memory abilities than are older adults. this result was obtained whether the younger group ...20071838980
[instruction in self care by patients with chronic respiratory failure]. 20072630706
new advances in anesthesia.pharmacologic advances in anesthesia over the last decade have focused on drug safety, shorter durations of action, reversibility, and ease of administration. this is reflective of major changes in the focus of patient care from inpatient to outpatient settings as well as from available risk management data that support the investigation of these new drugs. the pharmacologic advances discussed included those drugs in current practice as well as experimental drugs yet to be released for general c ...20072047291
the effects of race on norepinephrine clearance.eighteen normotensive and 19 unmedicated hypertensive black and white male subjects were studied twice, during a 10 meq sodium diet for 5 days and a 200 meq sodium diet for 4 days. the subjects received an infusion of 3h-norepinephrine (3h-ne) during both low and high sodium diets to measure ne clearance. dietary sodium and blood pressure classification had no effect on 3h-ne clearance. infusion of pressor doses of ne also failed to alter 3h-ne clearance. both normotensive and hypertensive black ...20071865747
[patient's autonomy--it can be supported]. 20071797178
percutaneous transjugular portosystemic shunt.--to determine the effectiveness of the palmaz balloon expandable stent for the creation of a transjugular intrahepatic portosystemic shunt. the device is designed to achieve portal decompression in patients with variceal hemorrhage secondary to portal hypertension.20071829120
[health economics--stopgap measures are no decisions. interview by kaj nyman]. 20062095080
if reliance on epidemiology were to become epidemic, we would need to assess its social validity. 20061890043
if reliance on epidemiology were to become epidemic, we would need to assess its social validity. 20061890043
effects of stimulus level on forward-masked psychophysical tuning curves in quiet and in noise.forward-masked psychophysical tuning curves were obtained from normal-hearing listeners at different probe levels in quiet and in a broadband background noise. in quiet, tuning-curve shape changed with probe level. for six listeners, tuning curves became broader with increasing probe level, primarily due to a decrease in the low-frequency slopes. for one listener, tuning curves became narrower with increasing probe level. the addition of a background noise, which was presented continuously at a ...20062269730
results of meniscal repair and partial meniscectomy in stable knees.in a study using matched pairs of 50 patients, meniscal repair was compared with partial meniscectomy in knees without major ligament injuries. there was a failure rate of 24% after meniscal repair in a follow up from 6 to 9 years after operation. a further meniscectomy was needed in 16% of those who had had a partial meniscectomy. function was better after meniscal repair, but the compliance rate was lower because of the prolonged rehabilitation. repair led to less osteoarthritis than menisecto ...20061809716
[intrapericardial lipoma with stenosis of the left bronchus and pulmonary artery].in a 1-year-6 month-old girl with asthma, a chest magnetic resonance imaging revealed an intrapericardial lipoma at the site of the transverse sinus behind the great arteries. the tumor compressed the left bronchus and pulmonary artery resulting in the stenosis. under cardiopulmonary bypass, the tumor was successfully removed. the stenosis of the left bronchus and pulmonary artery were released.20061593168
endobronchial rupture from endotracheal reintubation with an endotracheal tube guide.endotracheal tube guides are often used to facilitate endotracheal tube exchange in patients whose airways are difficult to intubate. the absence of reported complications with this technique suggests it is a safe technique; however, we report a case of endobronchial rupture associated with such a guide. diagnosis and management of tracheobronchial tears and alternative approaches to difficult reintubation are described.20062627389
effects of propofol on cerebral hemodynamics and metabolism in patients with brain trauma.the authors determined the effect of propofol on cerebral blood flow, intracranial pressure, and cerebral arteriovenous oxygen content difference in severely brain-injured patients during orthopedic treatment of fractures of the extremities. the glasgow coma scale score was 6 or 7 at the time of the study. data were collected in the operating room before and during (5 and 15 min) administration of propofol (2 mg/kg iv bolus immediately followed by a 150 micrograms.kg-1.min-1 infusion) before sur ...20062118315
in memoriam: peter mitchell, 1920-1992. 20061474903
[a case of turner's syndrome with ulcerative colitis]. 20062600511
the correlation of middle ear aeration with mastoid pneumatization. the mastoid as a pressure buffer.atelectatic ears, which by definition are poorly aerated, are also usually associated with poor mastoid pneumatization. on the other hand, otosclerotic patients, whose middle ears are usually exceptionally well aerated, also have excellent mastoid pneumatization. three unusual cases are presented, in which partial atelectasis developed in stapedectomized patients. in each case the mastoid was later found to be nonpneumatized, and further analysis revealed that their stapes fixation had in effect ...20061418937
acute improvement of cardiac function with intravenous l-propionylcarnitine in humans.as the myocardial carnitine content, a key control factor in myocardial oxidative metabolism and energy transfer, is reduced in heart failure, administration of l-propionylcarnitine (lpc), a potent analogue of l-carnitine, potentially may improve cardiac function, possibly through a positive inotropic effect. as its hemodynamic profile is unknown in humans, 32 fasting normotensive patients with coronary artery disease received either 15 mg/kg of lpc (n = 16) or vehicle (mannitol/acetate, n = 16) ...20061383625
higher formant normalization results from auditory integration of f2 and f3.two experiments were conducted to test the hypothesis that higher formant normalization results from the auditory integration of f2 and f3 when they are within 3 bark of each other. in the first experiment, formants 3-5 were manipulated in both a "hid"-"head" continuum (in which f2 and f3 are within 3 bark of each other) and a "hood"-"hud" continuum (in which f2 and f3 are not within 3 bark of each other). it was found that there was a shift in identification consistent with the higher formant n ...20062762105
the case of the case study. 20061367212
diaphragmatic movement using ultrasound during spontaneous and mechanical ventilation: effect of tidal volume.using ultrasound (us) the effect of various tidal volumes on the movement of ventral, dome and dorsal parts of the right hemidiaphragm was studied, both during spontaneous and mechanical ventilation. six healthy non-medicated volunteers who were in the supine position breathed spontaneously shallowly (tidal volume (vt) being 400 ml) (sb), and deeply (vt 1000 ml) (sb-deep). in addition, they were mechanically ventilated with intermittent positive pressure ventilation at three different vt's: 500 ...20061449048
[endoscopic ultrasonographic study of gastric ulcer treated with proton pump inhibitor].we examined 70 cases of gastric ulcer by endoscopic ultrasonography. of these, 18 cases were treated with proton pump inhibitor (ppi), another cases were treated with histamine h2 receptor antagonist or mucosal protective drugs. the endoscopic cumulative healing rate at the eighth week was 71.4% in all gastric ulcers. on the other hand, all of gastric ulcers treated with ppi were healed within eight weeks endoscopically. gastric ulcers which were revealed ultrasonographically to be refractory wi ...20061347334
scut: clinical data organization for physicians using pen computers.the role of computers in assisting physicians with patient care is rapidly advancing. one of the significant obstacles to efficient use of computers in patient care has been the unavailability of reasonably configured portable computers. lightweight portable computers are becoming more attractive as physician data-management devices, but still pose a significant problem with bedside use. the advent of computers designed to accept input from a pen and having no keyboard present a usable computer ...20061483012
reform and restructuring in nursing education: a necessity for nursing's future in florida. 20061563527
[multifactorial studies of 154 fatalities of psychotropic drug poisoning].the documents of 154 drug victims dissected in the centre of legal medicine of the university of frankfurt am main in 1987 and 1988 were examined by computer. the average age i.e. was 26 years, the share of women 23 per cent. in 47 per cent the main cause of death was an overdoses of heroin and in 48 per cent heroin was the first drug that was taken. 58 per cent of the drug victims came from totally intact families.20061489313
epididymitis in children and adolescents on clean intermittent catheterisation.the records of 119 children and adolescents on clean intermittent catheterisation (cic) were reviewed to assess the incidence and predisposing factors, if any, of epididymo-orchitis. cic had been performed for a total of 448 patient years with a mean of 4.5 years (range 3 months to 19 years). of the evaluable 99 patients, 10 suffered attacks of epididymo-orchitis after commencing cic. there was an equal incidence on both sides. three patients had recurrent attacks. epididymitis occurred at the r ...20061425846
present status of research abroad concerning the effect of acupuncture and moxibustion on immunologic functions.japan is one of the countries that have done extensive research on the effect of acupuncture and moxibustion on the immunologic functions. with china first, japan ranks second among the countries in this study. concerning research in this field concerned the level abroad can scarcely reach that in china. scholars abroad fail to base their research on tcm theory. in addition not only the type of diseases studied, and the indexes observed are far less than those in china, but also the scope of the ...20061453763
inhibition of trypsin by t-butyloxycarbonyl-alpha-aza-(4-aminophenyl)alanine phenyl ester.t-butyloxycarbonyl-alpha-aza-(4-aminophenyl)alanine phenyl ester (iii: r = nh2) has been synthesized. the rate of inhibition of trypsin (ec 3.4.21.4) by this compound (due to acylation followed by slower deacylation) shows a marked ph maximum at approximately 6. the shape of the ph-rate curve is discussed in terms of (i) the normal ph-activity curve of trypsin reacting with a charged substrate, i.e. the protonated form of the amino compound, (ii) the deprotonation of the 4-amino group with pka 4 ...20061367228
antithrombin budapest 3. an antithrombin variant with reduced heparin affinity resulting from the substitution l99f.the molecular basis and functional properties of a variant antithrombin (at) protein. at budapest 3, were studied. a single base substitution was identified in codon 99, ctc----ttc, altering the normal leucine to phenylalanine. the proband presented with a history of venous thrombotic disease and was found to be homozygous for the mutation. the variant protein demonstrated reduced heparin affinity and reduced antiproteinase activity in the presence of either unfractionated heparin or the at-bind ...20061555650
sister chromatid exchange (sce) frequency in lymphocytes of patients with colorectal carcinoma treated with razoxane.the increased risk of neoplasia following cytotoxic therapy for both malignant and nonmalignant disease is well known. sister chromatid exchange (sce) frequencies in patients receiving such chemotherapy are often elevated, and the persistence of high levels after treatment may provide an indicator for susceptibility to secondary neoplasia. the cytostatic drug razoxane has been used for the treatment of psoriasis, acute myeloid leukemia (aml), and colorectal carcinoma. prolonged use of this drug, ...20061458513
[laser therapy of external genital lesions]. 20061563686
epidemiology of respiratory hazards: recent advances.a bibliographical review of epidemiological studies published over the last five years has led us to individualize the themes that have been the subject of most recent publications (table i). these research themes are not new, which shows a certain continuity in epidemiological research on the respiratory risks of occupational origin. few studies are devoted to the identification of unrecognized respiratory risks; nevertheless, the methodology used, the indicators of effects studies contribute t ...20061626104
[the causes of cerebral complications in patients with ischemic heart disease following myocardial revascularization operations].in the period from jan. 1988 to jan. 1991 operations for the formation of an aortocoronary shunt were carried out in 437 patients at the department of combined affections of the coronary and peripheral arteries, bakulev research institute. in some cases the operation was combined with resection of a postinfarction aneurysm of the left ventricle. cerebral complications developed in the postoperative period in 28 (6.4%) patients. their analysis showed the prevalence of severe forms of consciousnes ...20061482586
interictal hm-pao spect: a routine investigation in patients with medically intractable complex partial seizures?single photon emission computed tomography (spect) is increasingly being used as an adjunctive technique in the localisation of epileptogenic foci prior to surgery. as yet, few studies have been undertaken to establish the clinical associations of areas of reduced cerebral perfusion. sixty-three consecutive patients (15 male, 48 female; median age 30 years, range 14-57 years) with medically intractable complex partial seizures (median/month 8, range 1-36) were investigated as outpatients. all ha ...20061478200
the relation of communication and language development to mental retardation. 20061418929
solitary cervical lymphoma presenting as a neurofibroma.a patient is described who presented with cervical cord compression. the imaging and operative findings were typical of a neurofibroma of the right third cervical root. however, histological studies confirmed that the tumour was a b-cell lymphoma. isolated spinal lymphomas can therefore occur and may present as nerve sheath tumours.20061472324
aspects of the analytic relationship.in this article the analysand-analyst relationship is investigated from the classical and from the post-classical point of view. this leads to the distinction of four fundamental aspects of the analytic relationship: the realistic relationship, the working relationship, the transference relationship, and the primary relationship. similarities and differences between these various aspects of the analytic relationship are discussed. examples of confusion about the aspects are given. disagreement a ...20061797722
aspects of the analytic relationship.in this article the analysand-analyst relationship is investigated from the classical and from the post-classical point of view. this leads to the distinction of four fundamental aspects of the analytic relationship: the realistic relationship, the working relationship, the transference relationship, and the primary relationship. similarities and differences between these various aspects of the analytic relationship are discussed. examples of confusion about the aspects are given. disagreement a ...20061797722
central nervous system and langerhans' cell histiocytosis. 20061694006
marking width, calibration from tip and tine diameter of periodontal probes.the present study comprises an investigation of 7 different probe types, representing currently-marketed major designs (who-cpitn, williams, michigan), as well as available calibration systems (engraved, etched and painted markings). width of markings, accuracy of calibration from probe tip, and tine diameter at the tip and at specified points along the tine were assessed, using a stereomicroscope at a magnification of x 40. blind duplicate measurements of these probe tine characteristics were 1 ...20061894745
hepatitis b antigen (hb-ag, australia antigen) in mixed saliva of patients with hb antigenemia. 20064125676
pancreatic apudomas. 20062885951
increases in knowledge and use of information technology by entering medical students at mcmaster university in successive annual surveys.to determine self-reported microcomputer and information technology competency, access, and usage by entering medical students and their perceptions of the need for training in additional applications.20061482936
37 aids clinical trials units funded by niaid. 20061594749
[differentiation therapy of acute promyelocytic leukemia: two successful cases of remission induction by all-trans retinoic acid].we described two pediatric patients with acute promyelocytic leukemia (apl) who were successfully induced into complete remission with all-trans retinoic acid (atra, 45 mg/m2 per day) after failing on conventional chemotherapy. initial response was observed as correction of dic within a week of treatment. hematologically, initial increase of maturing leukocytes reached a peak peripheral wbc count on the 16th and 20th day, respectively. however, these seemingly differentiated leukocytes retained ...20061635178
total exenteration, two or one ostomy.total exenterations require fecal and urinary diversions, necessitating ostomies in the anterior abdominal wall. this article was done to explore the possibility of extremely low anastomoses of the intestine to the anal stump, to reduce the number of ostomies to only one for the urinary diversion. although technically feasible, the long term follow-up evaluation of these patients resulted in us having reservations concerning function.20061636136
the resurgence of free radicals. 20061447450
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