Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| the immunogenic and pathogenic potential of short poly(c) tract mengo viruses. | we have shown previously that genetically engineered mengo viruses with artificial deletions in their 5' noncoding polyribocytidylic acid (poly(c)) tracts are highly attenuated for the natural murine host and also for other animals such as baboons, macaques, and domestic pigs. the present report further characterizes select short poly(c) tract mengo viruses in the natural murine host. a positive correlation was found between the length of the poly(c) tract and murine virulence, as measured by vi ... | 1996 | 8806569 |
| geographic population structure and sequence divergence in the mitochondrial dna control region of the japanese wild boar (sus scrofa leucomystax), with reference to those of domestic pigs. | mitochondrial dna (mtdna) control regions from 40 japanese wild boars were examined by direct sequencing after amplification by pcr. from the dna sequences obtained, we found eight haplotypes, whose differences arose via transitions. the geographical distribution of these different haplotypes indicated that wild boar populations inhabited limited areas and that there was some restricted gene flow between local populations. eight mtdna haplotypes from eastern and western domestic pigs and the ryu ... | 1996 | 8813051 |
| an outbreak of japanese encephalitis in the torres strait, australia, 1995. | to determine the distribution of virus infection during an outbreak of japanese encephalitis (je) in the torres strait, and to describe the environmental factors facilitating the outbreak. | 1996 | 8816682 |
| serum concentrations of melatonin in prepubertal gilts exposed to either constant or stepwise biweekly alteration in scotophase. | melatonin (mel), a hormone known to mediate photoperiodic cues, is secreted from the pineal gland in a circadian fashion in numerous species. the transduction of photoperiodic information into the secretion of mel, however, remains controversial in the pig. to determine whether domestic pigs have a nocturnal increase in serum melatonin when exposed to equatorial photoperiods only, 24 prepubertal gilts (38.7 +/- 0.7 kg; 104.5 +/- 0.8 d) and 12 mature ewes, serving as positive controls, were rando ... | 1996 | 8839625 |
| characterisation of bradykinin receptors from juvenile pig coronary artery. | coronary artery rings from juvenile male farm pigs were incubated for 6 h and precontracted with u46619. the rings relaxed in response to des-arg9-bradykinin (pd2, 7.78 +/- 0.13; emax, 87.4 +/- 4.3%) and to bradykinin (pd2, 8.69 +/- 0.30; emax, 104.2 +/- 4.4%). these responses were abolished by endothelium removal and unaffected by indomethacin whilst ng-nitro-l-arginine reduced the relaxation due to des-arg9-bradykinin only. preincubation with cycloheximide or actinomycin had no effect against ... | 1996 | 8851166 |
| protection of non-murine mammals against encephalomyocarditis virus using a genetically engineered mengo virus. | genetically engineered mengo viruses with artificial deletions in the 5' noncoding poly(c) tracts are highly attenuated for pathogenicity when introduced as live vaccines into the natural murine host. inoculation produces lifelong protective immunity without disease or viral persistence. this report extends the vaccination studies to non-murine hosts, including baboons, macaques and domestic pigs, all of which are susceptible to severe cardiovirus epizootics. all animals of these species that we ... | 1996 | 8852413 |
| a comparison of the pathophysiologic effects of carbon dioxide, nitrous oxide, and helium pneumoperitoneum on intracranial pressure. | previous studies have suggested that diagnostic laparoscopy may be contraindicated in multiple trauma patients with closed head injuries because of the detrimental effects of carbon dioxide (co2) pneumoperitoneum on intracranial pressure (icp). in this study we compared the effects of two alternative inflation gases, helium (he) and nitrous oxide (n2o), against the standard agent used in most hospitals, co2. icp was monitored in experimental animals both with and without a space occupying intrac ... | 1996 | 8862077 |
| the soft tissue cover of the mandibular condyle: age-related changes in high buoyant density proteoglycans, free tissue water and remodelling activity. | age-related changes in the relative proportion of high buoyant density proteoglycans of the soft tissue cover of the mandibular condyle of domestic pigs and the chemical composition of these proteoglycans were investigated by biochemical methods. the relative proportion of high buoyant density proteoglycans has been shown to decrease with age, with their chemical composition varying as follows: with age, the relative proportions of protein increased, galactosamine decreased, glucosamine was simi ... | 1996 | 8874176 |
| starling resistor effects on pulmonary artery occlusion pressure in endotoxin shock provide inaccuracies in left ventricular compliance assessments. | assessment of left ventricular preload and left ventricular compliance changes in septic shock using pulmonary artery occlusion pressure (paop) presumes that this pressure accurately reflects left heart filling pressure. we tested the hypothesis that starling resistor forces render paop inaccurate as an index of left heart filling pressure, resulting in misleading assessments of left ventricular compliance changes. | 1996 | 8874296 |
| the prepubertal ontogeny of luteinizing hormone releasing hormone-like immunoreactivity in the diencephalon and telencephalon of the male meishan pig brain. | luteinizing hormone releasing hormone (lhrh) is a decapeptide that regulates reproductive function and behaviors in mammalian species. because of the importance of proper reproductive function and efficiency in agricultural species, we have investigated the prepubertal ontogeny of lhrh-like immunoreactivity (ir) in the male meishan pig. the meishan is a chinese breed known for reproductive traits including increased litter size and precocious puberty, but slow growth and obesity. brains of anima ... | 1996 | 8874890 |
| transorbital approach to the porcine pituitary. | a transorbital approach to the pituitary gland is described in domestic swine weighing between 40 and 70 kg. a transpalpebral eye exenteration is performed and the optic canal is enlarged caudally, using a bone drill. an operating microscope is used to improve visualization of the surgical site as the pituitary stalk and anterior pituitary are exposed to the level of the optic chiasm. this approach exposes the pituitary sufficiently to perform either a hypophyseal stalk transection or a hypophys ... | 1996 | 8887068 |
| effectiveness of fibrin glue in the reduction of postoperative intrapericardial adhesions. | the hemostatic properties of fibrin sealant have been well described. previously published reports have attempted to clarify the possible role of fibrin glue in the inhibition of the formation of intrapericardial adhesions following cardiac surgery. earlier work hypothesized that fibrin glue may reduce the severity of postoperative adhesions and that the use of autologous fibrin glue may have similar effects, without the risks that accompany homologous blood products. six juvenile farm pigs were ... | 1996 | 8887071 |
| isolated coronary artery transplantation in pigs: a new model to study transplantation arteriosclerosis and humoral rejection. | graft atherosclerosis is a major cause of death after heart transplantation; its causes are multifactorial and poorly understood. to determine whether specific sensitization to coronary artery antigens is a contributing factor, we developed an isolated coronary artery allotransplantation model in pigs. | 1996 | 8889988 |
| location of external anal sphincter motoneurons in the sacral cord of the female domestic pig. | the location of the striated external anal sphincter motoneurons in the spinal cord was investigated in 12, between 3 and 4 months old, female domestic pigs using the retrograde tracer horseradish peroxidase (hrp). their motoneuronal cell bodies were found in the spinal segments s1-s3, and were not located in the ventral horn, but dorsolateral to the central canal. this location within the spinal gray matter strongly differs from the location of the external and sphincter motoneurons in rat, cat ... | 1996 | 8897493 |
| repair of a mid-diaphyseal femoral fracture in a boar. | a simple, oblique fracture of the middle portion of the diaphysis of the right femur was successfully repaired in a 10-month-old 150-kg berkshire boar, using a 4.5-mm 9-hole broad dynamic compression plate applied to the lateral surface of the bone. a lateral surgical approach provided excellent access to the fragment ends. intravenous administration of atracurium besylate facilitated traction along the long axis of the bone and fracture reduction. the plate was luted with 5% gentamicin sulfate- ... | 1996 | 8899028 |
| neonatal hemodynamic responses to extreme ranges of controlled graded hypoxia. | to determine the hemodynamic responses to a wide range of specific, controlled, graded levels of hypoxic hypoxia over 120 mins in a neonatal porcine model and to identify the pao2 threshold for altered hemodynamic homeostasis. | 1996 | 8917041 |
| husbandry and diseases of captive wild swine and peccaries. | wild swine and peccaries are popular exhibit animals throughout the world, but the anatomy and behaviour of these species make it difficult to construct housing and enclosures which are suitable from an aesthetic and sanitation standpoint. african wild suids may serve as reservoir hosts for african swine fever. likewise, african suids are susceptible to most of the viral, bacterial and parasitic diseases of domestic swine. wild swine and peccaries are not an important source of zoonotic diseases ... | 1996 | 8924700 |
| a karyotypic analysis of the lesser malay chevrotain, tragulus javanicus (artiodactyla: tragulidae). | chevrotains are small forest-dwelling ruminants of the family tragulidae. the chromosome number of the lesser malay chevrotain was determined to be 2n = 32, nf = 64, g- and q-banding allowed the identification of homologous chromosomes, and c-banding demonstrated the presence of pericentromeric, telomeric and interstitial constitutive heterochromatin. q-band comparisons with domestic cattle revealed relatively few monobrachial chromosome band homologies. however, the smallest biarmed autosome of ... | 1996 | 8939367 |
| the continent sigmoid urinary reservoir--an experimental study in pigs. | to evaluate the function of a continence mechanism in combination with a colonic urinary reservoir in a pig model. | 1996 | 8944507 |
| increased cardiac fatty acid uptake with dobutamine infusion in swine is accompanied by a decrease in malonyl coa levels. | malonyl coa is an important regulator of fatty acid oxidation in the heart secondary to its ability to inhibit carnitine palmitoyltransferase 1 (cpt 1). malonyl coa is produced from acetyl coa in a reaction catalyzed by acetyl coa carboxylase (acc). in this study we determined if alterations in malonyl coa regulation of fatty acid metabolism are involved in the increase in energy transduction seen following an increase in cardiac work. | 1996 | 8944819 |
| histopathologic appearance of arterial occlusions with hydrogel and polyvinyl alcohol embolic material in domestic swine. | this study observes the histologic changes resulting from a hydrogel embolic agent (polyacrylonitrile [pan]) compared with polyvinyl alcohol particles (pva) of similar size. | 1996 | 8951758 |
| impaired bronchial healing after lung donation from non-heart-beating donors. | bronchial viability after lung transplantation remains a concern. modern preservation methods, surgical technique, and limited cold ischemic periods have decreased the frequency of bronchial complications. however, lungs procured from non-heart-beating donors are subjected to a mandatory period of warm ischemia. we investigated bronchial healing in a porcine survival model of left lung transplantation using organ procurement from non-heart-beating donors after a 60-minute period of warm ischemia ... | 1996 | 8956117 |
| effects of left heart assist on geometry and function of the interventricular septum. | right ventricular (rv) dysfunction is a common but poorly understood problem associated with mechanical left heart assist (lha). left ventricular unloading may affect rv function even in normal hearts by altering geometry or function of the interventricular septum, although such changes have not been well defined. accordingly, the purposes of this study were to quantify the effects of lha on septal geometry and function in normal swine and to assess the resultant effects on rv function. | 1996 | 8957382 |
| cardiovascular function during the postresuscitation phase after cardiac arrest in pigs: a comparison of epinephrine versus vasopressin. | the administration of vasopressin during cardiopulmonary resuscitation (cpr) provides significantly more vital organ blood flow when compared with epinephrine during cardiac arrest in pigs. the effects of this potent vasoconstrictor on postresuscitation cardiovascular function remain unknown. the purpose of this study was to compare the effects of vasopressin and epinephrine on cardiovascular function in the postresuscitation phase after cpr. | 1996 | 8968270 |
| an ikappab homolog encoded by african swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host macrophages. | cytokines stimulate inflammatory defenses against viral infections. in order to evade host defenses, viruses have developed strategies to counteract antiviral cytokines. african swine fever virus (asfv) is a large, double-stranded dna virus that infects macrophages. this study demonstrates that asfv effectively inhibited phorbol myristic acid-induced synthesis of antiviral, proinflammatory cytokines alpha interferon, tumor necrosis factor alpha, and interleukin-8 in infected macrophages as asses ... | 1996 | 8970976 |
| nadph-diaphorase expression of endothelial cells during four weeks' healing of a stretch-eptfe graft: an experimental porcine study. | endothelial nitric oxide synthase (enos) mediates the conversion of l-argine to no and citrulline, which requires nicotinamide adenine dinucleotide phosphate (nadph) as an essential cofactor. evidence has been given that nos accounts for the nadph-diaphorase activity. the aim of the present study was to identify the histochemical and immunocytochemical appearance of nadph-diaphorase and von willebrand factor (factor viii) respectively, in endothelial cells (ecs) during healing of stretch-expande ... | 1996 | 8971580 |
| comparative ureteral microanatomy. | several animals have been used as models for experimental upper urinary tract surgery. although minipigs have recently gained favor because their upper urinary tract is grossly similar to that of humans, the ureteral microanatomic features of the two species have not been compared. we evaluated the histologic features of human and animal ureters in order to provide addition information regarding experimental models for upper urinary tract surgery. cross-sections of upper, middle, and lower urete ... | 1996 | 8972786 |
| ectopic locations of taenia saginata asiatica cysticerci in the abdominal cavity of domestic pig and monkey. | eleven small-ear-miniature pigs, 1 landrace small-ear-miniature pig, and 1 monkey (macaca cyclopis) were infected experimentally with eggs of taenia saginata asiatica. they were found to harbor cysticerci on the liver surface, each with a thin, whitish fiber connecting to another location in the same lobe, or to other lobes of the liver; some were also connected individually to the diaphragm, abdominal muscles, and gall bladder with a short, thin fiber. moreover, they also harbored extrahepatic ... | 1996 | 8973419 |
| isolation of encephalomyocarditis virus from dormice (myoxus glis) in italy. | two isolates of encephalomyocarditis (emc) virus (zrc 276ra/90 and zrc 292ra/90) were isolated from two dormice (myoxus glis) in tuscany, italy. the two isolates were lethal for laboratory mice and caused a rapid cytopathic effect characterized by rounded and wrinkled cells in both baby hamster kidney cells (bhk21) and african green monkey kidney cells (vero). we found neutralizing antibodies against emc virus in 408 (77%) of 529 domestic pigs (sus scrofa scrofa) and in 165 (49%) of 338 wild boa ... | 1995 | 8583644 |
| consequences of selection on muscle composition. a comparative study on gracilis muscle in wild and domestic pigs. | european domestic pigs are derived from the european wild pig by genetic selection and differ in their muscular-growth ability. thus, it was the aim of this study to investigate the consequences of genetic selection on muscle composition and fibre size in the gracilis muscle. fibre typing based on the atpase reaction revealed that this muscle in wild pigs is composed mainly of type-i and -iia fibres, whereas, in domestic pigs, type-iib fibres were predominant. for all fibre types, domestic pigs ... | 1995 | 8588708 |
| classical swine fever in wild boar (sus scrofa)--experimental infections and viral persistence. | a pregnant wild boar and two wild boar weaners were inoculated intranasally with a field isolate of classical swine fever virus (csfv) recently derived from a diseased domestic pig. the clinical, pathological and haematological findings noted in the young wild boars were comparable to those in domestic weaner pigs inoculated with the same virus isolate. both wild boars showed the acute haemorrhagic form of csf, one animal died 18 days post inoculation (p. i.) and the second one had to be euthani ... | 1995 | 8591736 |
| morphological investigations of the glandulae profundae plicae semilunares conjuctivae in the domestic swine (sus scrofa domesticus) and the wild hog (sus scrofa ferus). | samples of glandulae profundae plicae semilunares (harderian glands) from five domestic swine and five wild hogs were used for this research. the gland samples were fixed in bouin solution and mounted in paraffin. the paraffin slices were stained with haematoxylin and eosin, according to the periodic-acid-schiff (pas) method, with alcian blue (ph 2.5), with toluidine blue (ph 4.0), and applying a combination of staining with alcian blue (ph 2.5) and the pas method. in domestic swine and wild hog ... | 1995 | 8592973 |
| peculiarities of the connection between mesangial and glomerular endothelial cells in the domestic-swine kidney. | the peculiarities of the connection between mesangial and endothelial cells are investigated in material from non-perfused swine kidneys. it is established that cytoplasm fragments of the endothelial cells, located between the mesangial angles, abruptly extend their size, and borders between them are difficult to discern. they possess single microvilli on their lumenal surface, some of which are highly corrugated, branched and fenestrated. in those parts, the mesangial-cell excrescences are tigh ... | 1995 | 8592974 |
| microscopical and ultrastructural studies of the renal artery in domestic swine. | both renal arteries from six, 8-month old, camborow hybrid pigs were examined in histological, semithin and ultrathin sections. it was established that the membrana elastica interna showed an expressed degree of wrinkliness. in certain sections, sometimes occupying 20% of the diameter of across-section, its curves were considerably higher and wider than those in the remaining part. the inner elastic membrane in these sections was cleaved in two layers. estates of lengthwise-situated smooth muscl ... | 1995 | 8592976 |
| [an outbreak of brucellosis in pigs and conclusions derived on the epidemiology of this animal disease]. | the examination of an outbreak of brucellosis in domestic pigs showed unambiguously the existence of a natural focus of infection in the population of wild boars. contrary to former assumptions persistence of br. suis, biovar 2, to occur mainly in the population of hares, evidently a change of hosts has taken place. possible cause might be a contrary development of the density of these wild animal populations. health control of wild animals should not be neglected, as it is an important part of ... | 1995 | 8593137 |
| mr imaging of gadolinium-dtpa-bma-enhanced reperfused and nonreperfused porcine myocardial infarction. | to investigate whether gd-dtpa-bma-enhanced mr imaging permits differentiation between reperfused and nonreperfused myocardial infarction, myocardial infarction was induced in 12 domestic pigs. in 6 pigs, gd-dtpa-bma, 0.3 mmol/kg b.w. was administered i.v. 60 min after the occlusion. in 6 other pigs, the infarctions were reperfused 80 min after the occlusion, followed by injection of gd-dtpa-bma after 20 min of reperfusion. radiolabeled microspheres were used to confirm zero-flow during the occl ... | 1995 | 8519575 |
| pathogenicity of artyfechinostomum oraoni in naturally infected pigs. | in an attempt to establish the diarrhoeogenic potential of the newly identified artyfechinostomum oraoni, which was associated with human diarrhoea in a tribal community near calcutta, india, two naturally infected domestic pigs of the locality were followed in captivity. both pigs developed fatal diarrhoea after 5 months. the autopsy revealed a massive infection with the echinostome on a haemorrhagic and oedematous mucosa of the jejunum and duodenum extending up to pyloric end of the stomach. i ... | 1995 | 8525286 |
| genetic differences in recombination frequency in the pig (sus scrofa). | a comparison has been performed on 3 recently published linkage maps of the pig, hereafter designated as the american (a), european (e), and swedish (s) maps. the cumulated distances between common markers in these 3 maps were in the ratio 1.00 (a):0.88 (e):0.77 (s), in keeping with the ratio of the percentages of domestic genome in the reference families used to build the corresponding maps, i.e., 1.00 (a):0.81 (e):0.50 (s). from further recombination frequencies reported in wild boars (in the ... | 1995 | 8536996 |
| renal venous architectonics in domestic swine. | renal venous architectonics were investigated in 240 kidneys from 120 swines at an age of 1-8 months. the methods used were: preparation, corrosion and x-ray examination. it was established that, in 75% of the cases, v. renalis cranialis and v. renalis caudalis were present. in the rest of the cases (25%), v. renalis intermedia was present. it was also observed that right and left renal veins formed distentions, which enveloped the caudal medial part of each adrenal gland. v. adrenalis (supraren ... | 1995 | 8546320 |
| morphological studies of the valves of the kidney vein in domestic swine. | it was established macroscopically that 37.5% of the renal veins investigated possess valves. valves were observed on both sides, but predominantly on the left side of the kidneys (14.58%). some valves were also observed in the main branches of the renal veins. the structure of the valves was studied with the use of light and electron microscopy. the most important finding was the observation of mast cells in the valves. this is probably a common biological phenomenon, since mast cells have been ... | 1995 | 8546321 |
| histomorphologic and histochemical characteristics of carpal glands (glandulae carpeae) in domestic swine (sus scrofa domesticus) and wild swine (sus scrofa ferus). | investigations were carried out on samples from carpal glands of domestic and wild swine of different ages. the anatomic position of carpal glands is identical in domestic and wild swine. glandular acini in domestic swine are bigger and more scarce than in wild swine. ldh activity is more intense in wild swine, while the activity of the investigated diaphorases is almost even. the activity alkaline and acid phosphatase is stronger in domestic swine, while the activity of non-specific esterases i ... | 1995 | 8546329 |
| effects of dexmedetomidine on coronary hemodynamics and myocardial oxygen balance. | alpha 2-adrenergic agonists decrease central sympathetic outflow and maintain normal transmural myocardial blood flow distribution, but intravenous bolus doses of these agents can also induce excessive coronary vasoconstriction and myocardial ischemia. the hypothesis of the present study was that a rapid intravenous bolus of dexmedetomidine, a specific alpha 2-adrenergic agonist, will cause coronary vasoconstriction and accompanying myocardial ischemia in young pigs. | 1995 | 8547552 |
| augmentation of coronary blood flow by ace inhibition: role of angiotensin and bradykinin. | inhibition of the angiotensin converting enzyme (ace) is known to enhance coronary blood flow via partial suppression of angiotensin ii and potentiation of bradykinin. the purpose of these experiments was to evaluate the contribution of each of these mechanisms to the ace inhibition induced changes in blood flow in myocardial regions perfused by intact or stenotic coronary arteries. seven domestic swine were submitted to an 82% stenosis of the left anterior descending artery with the circumflex ... | 1995 | 8556004 |
| a closed-chest porcine model of coronary dissection and thrombosis. | coronary dissection and thrombosis are important as pathophysiological mechanisms in acute coronary syndromes and as consequences of various interventional procedures. the present study was designed to develop and characterize a simple percutaneous method to produce coronary dissection and thrombosis in the pig. | 1995 | 8574461 |
| a comparative study of open, laparoscopic intracorporeal, and laparoscopic assisted low anterior resection and anastomosis in pigs. | this study was done to investigate whether laparoscopic intracorporeal (li) or laparoscopic assisted (la) colon resection results in improved anastomotic healing compared with open colon resection (or). thirty-six domestic swine were randomly assigned to undergo either li, la, or or of the rectosigmoid. for or cases, the sigmoid was resected through a midline incision, and a transanal end-to-end stapled anastomosis was constructed with an ils device. for la and li cases, the sigmoid was laparosc ... | 1995 | 7887528 |
| dissociation between anti-infarct effect and anti-edema effect of ischemic preconditioning. | this study tested the hypothesis that preconditioning, by reducing catabolite accumulation during ischemia, reduces osmotic swelling and myocardial necrosis during subsequent reperfusion. farm pigs were randomly allocated to one of three groups of treatment: a control group undergoing a 48-min coronary occlusion (co) of the middle left anterior descending artery, a preconditioned group (2 cycles of 5-min co and 5-min reperfusion before the 48-min co), or an intracoronary perfusion group receivin ... | 1995 | 7840267 |
| polymerase chain reaction based genotyping for characterization of sla-dqb and sla-drb alleles in domestic pigs. | molecular genotyping of swine major histocompatibility complex sla-dqb and sla-drb genes using polymerase chain reaction (pcr)-based amplification is described. locus-specific oligonucleotide primers were designed for the analysis of expressed sla genes by reverse transcription-polymerase chain reaction (rt-pcr). rt-pcr products were sequenced, and the information gained was used to design primers for pcr genotyping of the exon 2 (beta 1) region from genomic dna templates. a single segregating a ... | 1995 | 7537478 |
| 5-ht3 receptor antagonism by anpirtoline, a mixed 5-ht1 receptor agonist/5-ht3 receptor antagonist. | 1. the aim of this study was to provide evidence that anpirtoline, which is an agonist at 5-ht1b and 5-ht1d receptors and also displays submicromolar affinity for 5-ht1a recognition sites, in addition, acts as an antagonist at 5-ht3 receptors. 2. in radioligand binding studies on rat brain cortical membranes, anpirtoline inhibited specific binding of [3h]-(s)-zacopride to 5-ht3 receptor recognition sites (pki: 7.53). 3. in n1e-115 neuroblastoma cells in which [14c]-guanidinium was used as a tool ... | 1995 | 7881726 |
| incompetence of domestic pigs as amplifying hosts of vesicular stomatitis virus for lutzomyia shannoni (diptera: psychodidae). | seven domestic pigs, sus scrofa l., were infected by intradermal inoculation at 3 different sites with the new jersey serotype of vesicular stomatitis (vsnj) virus. laboratory-reared lutzomyia shannoni dyar sand flies, a suspected biological vector of vsnj virus, were allowed to feed on pigs at the lower abdomen or at sites of their own selection on days 1-7 and on day 10 postinfection. blood samples were taken from infected swine concomitant with most feeding trials and tested for the presence ... | 1995 | 7473632 |
| renal perfusion: pharmacologic changes depicted with power doppler us in an animal model. | to evaluate the ability of power doppler ultrasonography to depict changes in renal perfusion after pharmacologic manipulations. | 1995 | 7480728 |
| sutured or fibrin-glued laparoscopic choledochojejunostomy. | minimally invasive techniques for choledochojejunostomy offer theoretical advantages for palliating unresectable periampullary neoplasms. fibrin glue, a biologic adhesive containing concentrated fibrinogen, may obviate suturing and promote healing without stricture formation. we examined the technical ability to perform laparoscopic choledochojejunostomy (lcj) and the applicability of thrombin-activated fibrin glue in an animal model of biliary obstruction. domestic pigs underwent laparoscopic c ... | 1995 | 7482208 |
| mr imaging of contrast-enhanced porcine myocardial infarction. assessment of reperfusion and tissue viability. | to assess the usefulness of dy-dtpa-bma-induced signal reduction, as an indicator of myocardial viability, myocardial infarction was induced in 17 domestic pigs by ligating a diagonal branch of the left anterior descending coronary artery (lad). in 6 pigs, dy-dtpa-bma (1 mmol/kg b.w.) was administered 4 hours after induction of ischaemia. in 5 additional pigs, gd-dtpa-bma (0.3 mmol/kg b.w.) and dy-dtpa-bma (1 mmol/kg b.w.) were simultaneously injected after 4 hours of ischaemia to ascertain whet ... | 1995 | 7484207 |
| number and distribution of silver-stained nucleolar organizer regions and evolutionary relationships in domestic pigs. | variation in the numbers of silver-stained nucleolar organizer regions (ag-nors) were examined in 36 breeds of domestic pig of different geographic origins and five subspecies of wild boar. the relationship between ag-nors and evolution of domestic pigs was investigated. in all pigs observed, ag-nors were localized on the secondary constriction of chromosomes 10 and 8. the mean ag-nor numbers varied from 2.0-4.0, and decreased gradually with the different geographical distribution from south to ... | 1995 | 7486245 |
| formation of the scab and the rate of epithelisation of superficial wounds in the skin of the young domestic pig. 1962. | 1995 | 7553187 | |
| localization of fragile sites in the karyotype of sus scrofa domestica: present status. | fragile sites were induced to expression in pig lymphocyte chromosomes by in vitro exposure to folate antagonists and budr-hoechst 33258. expressed fragility was localized according to the presented idiograms and compared with the location of known spontaneous translocations. | 1995 | 7558883 |
| laparoscopic assisted continent urinary diversion in the pig. | the ideal urinary reservoir would be low pressure, nonrefluxing and simple to construct. hohenfellner recently described creating an in situ ureterosigmoidostomy with a 5 to 6 cm. detubularized portion of sigmoid colon and rectum (sigmoid-rectum pouch). in an effort to further study the reconstructive applications of laparoscopy, we sought to laparoscopically create a sigmoid-rectum pouch in an animal model. in addition, we sought to compare a "dunked" (right ureter) with a hand-sewn end-to-side ... | 1995 | 7563387 |
| detection of hepatitis e virus infections among domestic swine in the kathmandu valley of nepal. | the prevalence of hepatitis e virus (hev) infections among 55 domestic swine living in the kathmandu valley of nepal was investigated. sera and stool specimens were collected from 47 free-roaming swine and examined for the presence of hev genomic sequences by the reverse transcription-polymerase chain reaction. sera from these animals, as well as sera from eight other swine, were also examined for the presence of hev-specific antibodies by an enzyme-linked immunosorbent assay and by a fluorescen ... | 1995 | 7573701 |
| [diagnosis of trichinellosis in living pigs using indirect elisa]. | a modified e/s-elisa based on the procedure described by gamble et al. (1988) was used for the diagnosis of trichinellosis in the domestic pig. the results of screening the sera of 92 pigs experimentally infected with trichinella larvae (t. spiralis, t. nativa) with different doses, confirmed that the e/s-elisa is suitable for the serological detection of trichinella-specific igg. although the serotest shows a high sensitivity especially in the case of a low infection rate, it can not be used as ... | 1995 | 7575386 |
| immunohistochemical demonstration of non-muscle myosin in the developing porcine epidermis. | using an immunohistochemical technique, the study demonstrates for the first time non-muscle myosin stress fibres in fetal mammalian epidermis, with special regard to cellular development during integumentary ontogenesis in the sparsely haired domesticated pig. the results obtained are discussed in view of possible cytoskeletal functions of the cytofilaments. | 1995 | 7577838 |
| chemical ablation of the gallbladder: is it feasible? | transcatheter ablation of the gallbladder has been attempted in animals and humans with a variety of chemical and physical agents. initial in vitro experiments suggested sodium hydroxide and hydrogen peroxide were more effective sclerosants than previously reported chemical agents. a phase i trial of escalating concentrations of and exposure times to these agents was performed in vivo. | 1995 | 7579863 |
| myocardial interstitial purine metabolites and lactate with increased work in swine. | dobutamine stimulates the beta-receptors in the heart and increases myocardial blood flow and oxygen consumption 2-3-fold, similar to effects seen with exercise. the purpose of this study was to assess temporal changes in myocardial interstitial purine metabolites, adenosine monophosphate (amp) and lactate during and following 30 min of dobutamine infusion. | 1995 | 7585825 |
| intracoronary low-dose beta-irradiation inhibits neointima formation after coronary artery balloon injury in the swine restenosis model. | neointima formation contributing to recurrent stenosis remains a major limitation of percutaneous transluminal angioplasty. endovascular low-dose gamma-irradiation has been shown to reduce intimal thickening (hyperplasia) after balloon overstretch injury in pig coronary arteries, a model of restenosis. the objective of this study was to determine whether the use of a beta-emitting radioisotope for this application would have similar effects and to examine the dose-response relations with this ap ... | 1995 | 7586273 |
| monitoring of tissue oxygenation in shock: an experimental study in pigs. | to evaluate different methods and markers for assessing adequacy of tissue oxygenation in shock. | 1995 | 7587236 |
| a new reciprocal translocation (7q+;15q-) in the domestic pig. | a reciprocal translocation was identified in a phenotypically normal large white boar. chromosome preparations from the carrier were studied by flow sorting, chromosome painting and g-banding. the flow karyotype displayed one additional clearly distinguishable peak, while in situ hybridization and g-banding showed two abnormal chromosomes involved in the translocation. all the results suggested that the translocation involved chromosomes 7 and 15 and the karyotype investigated was 38,xy,rcp(7;15 ... | 1995 | 7587395 |
| on the mechanism of skin wound "contraction": a granulation tissue "knockout" with a normal phenotype. | this report explores the mechanism of spontaneous closure of full-thickness skin wounds. the domestic pig, often used as a human analogue for skin wound repair studies, closes these wounds with kinetics similar to those in the guinea pig (mobile skin), even though the porcine dermis on the back is thick and nearly immobile. in the domestic pig, as in the guinea pig, daily full-thickness excisions of the central granulation tissue up to but not including the wound edges in both back and flank wou ... | 1995 | 7597065 |
| anastomotic diameter of circular stapled oesophagojejunal anastomoses and its implication for weight development. a clinical and experimental study. | to investigate the increase in diameter of the oesophagojejunal anastomosis after total gastrectomy with a circular stapler, and to assess experimentally the influence of oesophageal diameter on weight. | 1995 | 7599298 |
| débridement of the pig retinal pigment epithelium in vivo. | to study the morphologic effects of surgical débridement of the retinal pigment epithelium (rpe) in an animal model. | 1995 | 7605288 |
| comparative study of in vitro lipogenesis in various adipose tissues in the growing domestic pig (sus domesticus). | activities of acetyl-coa-carboxylase, malic enzyme and glucose-6-phosphate-dehydrogenase were measured in seven different anatomical sites in the growing pig (20-120 kg weight). the three enzyme activities increased up to 40-60 kg weight and then decreased, malic enzyme becoming the main producer of nadph, irrespective of the adipose tissue. subcutaneous adipose tissue of the neck area was much thicker and exhibited much lower lipogenic enzyme activities than backfat. subcutaneous adipose tissue ... | 1995 | 7613762 |
| lower esophageal sphincter pressure during prolonged cardiac arrest and resuscitation. | unprotected airway ventilation models have been based on a lower esophageal sphincter (les) pressure found in human beings under general anesthesia. whether this assumption is applicable during cardiac arrest in human beings is unknown. we attempted to determine the effects of prolonged ventricular fibrillation (vf) on the tension of the les in a swine model of cardiac arrest. | 1995 | 7618786 |
| percutaneous serial catheterization in swine: a practical approach. | in a model designed for experimental cryoablation of the his bundle in swine, a study that required multiple and follow-up cardiac catheterizations, femoral percutaneous cannulations were successfully performed in 14 of 15 swine: 6/6 yucatan miniature, 5/6 hanford miniature, and 3/3 yorkshire farm pigs, weight range 15-50 kg. a follow-up cardiac catheterization was performed in 10 of these animals: 5 hanford and 5 yucatan. femoral percutaneous cannulation was successful in 6. a cutdown approach ... | 1995 | 7619782 |
| swine model of haemophilus ducreyi infection. | haemophilus ducreyi is a strict human pathogen that causes sexually transmitted genital ulcer disease. we infected domestic swine with h. ducreyi 35000, resulting in the development of cutaneous ulcers histologically resembling human chancroid lesions. intraepidermal lesions progressed from pustules to ulcers containing polymorphonuclear leukocytes and were accompanied by a dermal inflammatory infiltrate containing t cells and macrophages. h. ducreyi was recovered from lesions up to 17 days afte ... | 1995 | 7622236 |
| chronic effects of misoprostol in combination with the nsaid, diclofenac, on gastrointestinal tract of pigs. relation to diarrheagenic activity, leukocyte infiltration, and mucosal leukotrienes. | to determine the mode of protective effects of misoprostol against the chronic gastrointestinal ulceration from the nsaid, diclofenac, studies were undertaken in domestic pigs, a model of human gastrointestinal ulceration, to determine (1) the effects of repeated daily dosing for 10 days of diclofenac 5 mg/kg/day twice a day (as voltaren tablets) on the gastrointestinal morphology, 59fe-red blood loss, mucosal myeloperoxidase (mpo) activity (as an indicator of leukocyte infiltration), and mucosa ... | 1995 | 7628265 |
| does hypoxia or hypercarbia independently affect resuscitation from cardiac arrest? | in a previous cardiopulmonary resuscitation (cpr) study in swine, ventilation was associated with improved rate of return of spontaneous circulation (rosc) compared with nonventilated animals, which had greater hypoxia and hypercarbic acidosis. we used the same model to determine the independent effect of hypoxia and hypercarbic acidosis on rosc after cardiac arrest. | 1995 | 7634893 |
| allopurinol improves myocardial reperfusion injury in a xanthine oxidase-free model. | the ability of allopurinol to protect against reperfusion injury in the heart has usually been attributed to its xanthine oxidase (xo)-inhibiting properties. human myocardium however, has exhibited low levels of xo activity. to investigate the effects of allopurinol in an xo-free model and determine whether pretreatment is necessary, 12 domestic pigs (15 kg to 20 kg) underwent occlusion of the left circumflex for 8 minutes followed by reperfusion for 4 hours. one group received allopurinol infus ... | 1995 | 7636893 |
| functional characteristics of a new coronary perfusion balloon: comparison with the flowtrack 40 in closed chest swine. | this study was designed to compare a new investigational coronary perfusion balloon (wave, scimed life systems inc.) with that of an approved, widely used, current generation device (flowtrack 40, advanced cardiovascular systems). domestic swine were anesthetized with pentobarbital and instrumented using standard percutaneous technique. left ventricular contractile function (dp/dt) was monitored using a micromanometer while intracoronary and surface ecgs were also recorded. eight target vessels ... | 1995 | 7656316 |
| mechanical ventilation may not be essential for initial cardiopulmonary resuscitation. | in a rodent model of cardiac arrest and resuscitation in which the inspired gas mixture was enriched with oxygen, resuscitability and survival were unaffected by positive pressure ventilation. in the present study, in a larger animal model, tidal volumes generated during precordial compression and with spontaneous gasping were quantitated. | 1995 | 7656640 |
| the need for ventilatory support during bystander cpr. | to compare cpr with chest compressions plus ventilatory support (cc+v) and chest compressions alone (cc). | 1995 | 7661426 |
| dysregulation of the veno-arterial response in the superior mesenteric artery during endotoxic shock. | to investigate whether the vascular dysfunction in endotoxic shock is associated with inhibition of the veno-arterial response of the superior mesenteric artery. | 1995 | 7664554 |
| dopamine-1-receptor stimulation and mucosal tissue oxygenation in the porcine jejunum. | to evaluate the effects of dopamine-1-receptor stimulation on intestinal mucosal tissue oxygenation. | 1995 | 7664559 |
| dynamics of myocardial metabolism in the preconditioned porcine heart studied using continuous microdialysis. | a microdialysis technique was used to measure myocardial catabolism of adenine nucleotides during preconditioning. following thoracotomy in domestic pigs, a probe was inserted into the ischaemic myocardium and two probes into normal myocardium. preconditioning was instituted by occluding a diagonal branch of the left anterior descending coronary artery four times over a 10 min period (interspersed with 20 min of reperfusion each time), followed by index ischaemia for 40 min and terminated by 20 ... | 1995 | 7671904 |
| sex differences in the distribution of estrogen receptors in the septal area and hypothalamus of the domestic pig (sus scrofa). | recently in the pig hypothalamus a vasopressin- and oxytocin-containing nucleus was identified which, like the supraoptic nucleus, becomes sexually dimorphic after puberty. following the increase in circulating steroids at puberty, the vasopressin- and oxytocin-containing nucleus becomes twice as large in both males and females. in adulthood, the vasopressin- and oxytocin-containing nucleus of females is approximately twice as large as that in males. because these alterations are possibly due to ... | 1995 | 7708211 |
| olfactory sensitivity to the pheromone, androstenone, is sexually dimorphic in the pig. | sexually dimorphic pheromone pathways have been used successfully to study insect olfactory coding. as one of the few mammalian species with an identified sex pheromone, the domestic pig (sus scrofa) may be an ideal vertebrate species in which to examine sex differences in olfactory processing of a specific stimulus. in this experiment, androstenone and control odor detection thresholds were measured in adult male, female, and castrated male pigs. in an operant task, pigs were tested with descen ... | 1995 | 7716200 |
| the pigmap consortium cytogenetic map of the domestic pig (sus scrofa domestica). | 1995 | 7749224 | |
| combination of vitamins c and e alters the response to coronary balloon injury in the pig. | restenosis is the major limitation of the long-term success of percutaneous transluminal coronary angioplasty. the process of restenosis involves repair of vascular injury and remodeling of vessel architecture. therapeutic interventions that improve vascular function may therefore be beneficial in the treatment of restenosis. antioxidants such as probucol and vitamins c and e have proved effective in improving endothelial function in hypercholesterolemia, inhibiting lipid accumulation in animal ... | 1995 | 7749812 |
| the pattern of coronary arteriolar bifurcations and the uniform shear hypothesis. | by minimizing the cost function, which is the sum of the friction power loss and the metabolic energy proportional to blood volume, murray derived an optimal condition for a vascular bifurcation. murray's law states that the cube of the radius of a parent vessel equals the sum of the cubes of the radii of the daughters. we tested murray's law against our data of pig's maximally vasodilated coronary arteriolar blood vessels at bifurcation points in control and hypertensive ventricles. data were o ... | 1995 | 7762878 |
| myocardial technetium-99m-teboroxime activity in acute coronary artery occlusion and reperfusion: relation to myocardial blood flow and viability. | the purpose of this study was to test the hypothesis that 99mtc-teboroxime retention within the heart depends at least in part on the presence of viable myocytes. | 1995 | 7769429 |
| effect of testosterone treatment on vasoconstrictor response of left anterior descending coronary artery in male and female pigs. | androgens may be risk factors in the pathogenesis of coronary artery disease by promoting coronary vasoconstriction. we studied the effect of testosterone treatment on coronary vascular reactivity of male and female domestic pigs treated for 2 weeks with either placebo or testosterone 10 mg/kg subcutaneous (s.c.) pellets. vascular reactivity was studied in ring segments (4-5 mm) isolated from the left anterior descending coronary artery (lad). no significant sex difference was noted in the respo ... | 1995 | 7769819 |
| laparoscopic partial splenic resection. | twenty domestic pigs with an average weight of 30 kg were subjected to laparoscopic partial splenic resection with the aim of determining the feasibility, reliability, and safety of this procedure. unlike the human spleen, the pig spleen is perpendicular to the body's long axis, and it is long and slender. the parenchyma was severed through the middle third, where the organ is thickest. an 18-mm trocar with a 60-mm endopath linear cutter was used for the resection. the tissue was removed with a ... | 1995 | 7773460 |
| [observational and experimental studies on relationship between domestic pigs and epidemic hemorrhagic fever investigation]. | observational and experimental studies on the relationship between domestic pigs and epidemic hemorrhagic fever (ehf) were carried out during 1986 to 1994 with reverse passive hemagglutination (rpha), reverse passive hemagglutination inhibition (rphi), horse-radish peroxidase-staphylococcal protein a (hrp-spa), indirect immunofluorescence assay (ifa) and reverse transcript polymerase chain reaction (rt-pcr) to understand the roles of domestic pigs played in the epidemic areas. results showed dom ... | 1995 | 8697938 |
| [zoo-anthroponoses in vojvodina. iv. epidemiologic characteristics of trichinosis in vojvodina]. | epidemiological characteristics of trichinellosis in vojvodina have been analyzed on the basis of registered cases of the disease, registration of epidemics and also epidemiological investigation of exposed persons. in the period 1984-1993, 1802 diseased persons were registered, 958 male and 844 female. death was registered in one case. average morbidity was 8.9/10(5). trichinellosis affects all age groups. at younger age the disease affects both sexes, but in the group over 20 years of age the ... | 1995 | 8657070 |
| immunocytochemical studies on endocrine cells of alimentary tract of the pig in the embryonic and fetal period of life. | the study aimed at immunocytochemical analysis of alimentary tract endocrine cells between 20th day of embryonal life and 105th day of fetal life of domestic pig. in the pancreas, presence of endocrine cells was detected already in 20th day and, at the time, the cells comprised around 3/4 all cells in primordia of the organ. starting at that time, numerous endocrine cells produced insulin and glucagon and individual cells synthesized somatostatin and pancreatic polypeptide. in the 20th day, stom ... | 1995 | 8606027 |
| interferon, the oxytocin receptor and the maternal recognition of pregnancy in ruminants and non-ruminants: a comparative approach. | ruminant and non-ruminant members of the artiodactyla appear to use different mechanisms for the maternal recognition of pregnancy. in ruminants, the trophoblast of the developing blastocyst produces a characteristic type i interferon of the interferon-tau family; this acts by blocking endometrial synthesis of the oxytocin receptor. a similar mechanism applies to domestic ruminants (sheep, cow, goat) and deer. in roe deer, which have embryonic diapause and are monoestrus, there is no requirement ... | 1995 | 8606939 |
| serological study of pigs for antibody against african swine fever virus in two areas of southern malawi. | a serological survey was conducted in july 1991 on domestic pigs in two areas of southern malawi which were severely affected by the african swine fever (asf) epizootic in 1989-1991. sixty-six of the 216 owners questioned reported having witnessed asf in their pigs. forty-seven owners had pigs with antibodies against asf virus, and the overall prevalence of pigs with anti-asf virus antibodies was found to be 12.4%, in 445 pigs sampled in 35 villages. spread of asf was thought to occur principall ... | 1995 | 8593400 |
| spontaneous agonal respiration in a swine model of out-of-hospital cardiac arrest. | to describe ventilatory dynamics following the onset of ventricular fibrillation (vf) in an experimental swine model. | 1995 | 8597915 |
| localization of landmarks and bands in the karotype of sus scrofa domestica. comparison between different classifications. | representative rbg-banded chromosomes of sus scrofa domestica and diagrammatic representation of the banding patterns at the 600 band stage are presented. comparison between different classification systems has been performed. it is suggested that the data presented can be applied to gene mapping, localization of chromosome aberrations, comparative cytogenetics, and translation between different classification systems. | 1995 | 8984097 |
| magnetic resonance imaging of the hepatobiliary system: intestinal absorption studies of manganese mesoporphyrin. | we studied the intestinal absorption of manganese mesoporphyrin (mn-mesoporphyrin), a potential oral hepatobiliary contrast agent. | 1995 | 9419672 |
| review of taeniasis in asia. | although asian taenia is closely related to t. saginata, it is a genetically distinct entity and can be distinguished from the classical t. saginata. man is the only definite host of this parasite. the domestic pig and wild boar in taiwan as well as domestic pig in korea have been determined to be the natural intermediate hosts. moreover, the pig has been demonstrated to be the most favorable experimental intermediate host. the cysticerci are situated mainly in the liver. they are smaller than t ... | 1995 | 9774987 |
| differential response to transforming growth factors-beta(1) and beta(2): connective tissue deposition in animal models. | the ability of transforming growth factor (tgf)-beta(1) and tgf-beta(2) to promote connective tissue deposition were compared in different animal models. a single subcutaneous injection of tgf-beta(2) in collagen/heparin gel carrier promoted markedly more extensive development of connective tissue than tgf-beta(1) at the site of injection in both neonatal and adult mice. both tgf-beta(1) and tgf-beta(2) promoted deposition of dense and well-vascularized connective tissue matrix infiltrated with ... | 1995 | 17147660 |
| in vitro development of embryos from sinclair miniature pigs: a preliminary report. | the goal of this project was to identify conditions that result in development from the zygote or the 2-cell stage sinclair miniature pig embryos to the blastocyst stage. four media were selected, 2 that have been shown to result in in vitro development in domestic pigs (hepes buffered tyrode's medium and whitten's medium), 1 that is compatible with similar development in the cow (cr-1), and 1 that is compatible with development in the mouse (czb). one- and two-cell stage embryos from sinclair m ... | 1995 | 16727687 |
| pancreatic contrast enhancement with mn-bis pyridoxal ethylene diamine diacetic acid and the influence of a hormonal stimulation of the pancreas in pigs. | pancreatic and hepatic contrast enhancement after different modes of administration of mn-bis pyridoxal ethylene diamine diacetic acid (mn-dpdp) and the influence of the hormones secretin and cholecystokinin on the uptake of this new contrast agent were studied by using magnetic resonance (mr) imaging and atomic absorption spectroscopy (aas) examinations carried out on 13 young domestic pigs. | 1994 | 9419495 |