Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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outcomes of carbapenem-resistant klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies. | carbapenem-resistant klebsiella pneumoniae is an emerging healthcare-associated pathogen. | 2008 | 18973455 |
highly resistant microorganisms in a teaching hospital: the role of horizontal spread in a setting of endemicity. | to determine the incidence density of highly resistant organisms (hros) and the relative contribution of horizontal spread in a setting of endemicity. | 2008 | 18973456 |
molecular characterization of nosocomial ctx-m type beta-lactamase producing enterobacteriaceae from a tertiary care hospital in south india. | ctx-m group of extended spectrum beta lactamases (esbls) represents a rapidly emerging problem in many countries. the prevalence of nosocomial bla ctx-m-1 producing enterobacteriaceae strains has not been reported earlier in indian hospitals. this study describes molecular subtyping of nosocomial bla ctx-m producing strains of enterobacteriaceae . polymerase chain reaction with primers specific for bla ctx-m-1 coding genes was used to identify 95 enterobacteriaceae strains producing bla ctx-m po ... | 2008 | 18974492 |
[meningoencephalitis due to community klebsiella pneumoniae in an adult immunocompetent: a case report]. | we report the first moroccan case of community-acquired meningoencephalitis due to klebsiella pneumoniae in an adult immunocompetent without medical history, complicated of cerebral vasculitis and right endophthalmitis. k. pneumoniae is exceptionally responsible for meningitis community in the world excepted in some countries of southeast asia. it usually occurs on fragile field and is associated with high mortality. the early management of the patient, the immunocompetent field and the wild phe ... | 2008 | 18957347 |
klebsiella pneumoniae pulmonary infection with thyroid abscess: report of a case. | thyroid abscess is a rare clinical entity, usually associated with a pyriform sinus fistula. a prompt diagnosis is important because it may progress rapidly into a life-threatening condition. we report a very unusual case of thyroid abscess associated with a lung infection, both caused by klebsiella pneumoniae. the patient was treated successfully with a culture-appropriate antibiotic and an uneventful thyroid lobectomy. a delay in diagnosis of morbidities associated with a thyroid abscess may r ... | 2008 | 18958563 |
klebsiella oxytoca necrotizing fasciitis after orthotopic heart transplant. | we report a case of klebsiella necrotizing fasciitis after heart transplantation. the infection required debridement of discontinuous areas on three extremities as well as on the trunk. klebsiella sp necrotizing fasciitis is a rare entity and has not been described previously in concert with heart transplantation. klebsiella cases classically have skip lesions as described herein. klebsiella oxytoca is a rare cause of necrotizing fasciitis in north america and presents with multifocal infection ... | 2008 | 18971102 |
evidence for clonal dissemination of the serotype k1 klebsiella pneumoniae strain causing invasive liver abscesses in korea. | seventy-three liver abscess isolates of serotype k1 klebsiella pneumoniae from a nationwide collection in korea were genotypically characterized using pulsed-field gel electrophoresis and multilocus sequence typing. we found that serotype k1 k. pneumoniae strains that caused liver abscesses in korea were genotypically related and that most were sequence type 23. | 2008 | 18971367 |
rhinoscleroma in a young adult with chronic rhinitis and dyspnea. | 2008 | 18816882 | |
bacteriological and clinical evaluation of twelve cases of post-surgical sepsis of odontogenic tumours at a referral centre. | to determine the bacterial aetiology of sepsis occurring following surgery of odontogenic tumours and assess the effect of prompt and proper antibiotic usage. | 2008 | 18817023 |
pyogenic liver abscess associated with septic pulmonary embolism. | septic pulmonary embolism (spe) is one of the metastatic foci of pyogenic liver abscess. the purpose of this study was to investigate the clinical presentations of, and management options for patients with pyogenic liver abscess complicated with spe. | 2008 | 18818136 |
non-susceptibility trends among enterobacteriaceae from bacteraemias in the uk and ireland, 2001-06. | enterobacteriaceae are common agents of bacteraemia, with escherichia coli accounting for 20% of the cases. reflecting this importance, members of the family constitute 4 of the 12 collection groups in the british society for antimicrobial chemotherapy (bsac) bacteraemia surveillance programme. | 2008 | 18819979 |
epidemiology of nosocomial infections in medicine intensive care unit at a tertiary care hospital in northern india. | this prospective observational study describes the rates of nosocomial infections (ni), the sites of infection, the pathogens involved, their antibiogram and the risk factors at a tertiary care hospital in northern india. in 62 of the 182 enrolled patients 95 episodes of ni were recorded (incidence rate 28.6/1000 person days): pneumonia (77%); urinary tract infection (24%) and blood stream infection (24%). all isolates of acinetobacter, pseudomonas and klebsiella and 83.3% of escherichia coli we ... | 2008 | 18820195 |
testing for the cemo, klebsiella pneumoniae and pseudomonas aeruginosa. | 2008 | 18820336 | |
spinal infection caused by esbl-producing klebsiella pneumoniae treated with temocillin. | a case of cervical epidural abscess in a 63-year-old woman with a complex gastrointestinal surgical history is reported. the presenting symptom was neck pain, and blood analysis demonstrated raised erythrocyte sedimentation rate and c-reactive protein. mr imaging of the cervical spine revealed cervical discitis, osteomyelitis, and epidural collection. an esbl-producing strain of klebsiella pneumoniae, isolated from a previous episode of bacteraemia, was the causative organism. surgical treatment ... | 2008 | 18804871 |
dualistic acidic and neutral glucose fermentation balance in small intestine: simulation in vitro. | intestinal microbes live in diminished or deprived oxygen conditions. facultative anaerobic bacteria of the family enterobacteriaceae ferment glucose in the gut using two main pathways: mixed acid and neutral fermentations. the aim of the present study was to clarify the roles of these fermentations in an in vitro model. acid-producing escherichia coli atcc 25922 and neutral end-products producing klebsiella mobilis atcc 13048 were cultured in a portable microbe enrichment unit (pmeu) which perm ... | 2008 | 18804970 |
sitafloxacin hydrate for bacterial infections. | sitafloxacin hydrate (du-6859a, gracevit), a new-generation, broad-spectrum oral fluoroquinolone that is very active against many gram-positive, gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in japan for the treatment of respiratory and urinary tract infections. sitafloxacin is active against methicillin-resistant staphylococci, streptococcus pneumoniae and other streptococci with reduced susceptibility to levofloxacin ... | 2008 | 18806900 |
[1, 3-propanediol production under salt stress]. | through studying the process of glycerol fermentation to 1, 3-propanediol(1, 3-pd) by klebsiella pneumoniae, it was found that the cell growth and product (or by-product) production were under salt stress. cell growth and product formation kept high rate at low salt concentration. high salt concentration led to low growth of cells, final concentration of 1, 3-pd and conversion from glycerol to 1, 3-pd, and, 1, 3-propanediol oxidoreductase activity decreased. when the salt concentration in 5 m3 b ... | 2008 | 18807999 |
role of klebsiella oxytoca in antibiotic-associated diarrhea. | klebsiella oxytoca was recently shown to be the causative agent of antibiotic-associated hemorrhagic colitis. because it is unclear whether k. oxytoca also causes nonhemorrhagic antibiotic-associated diarrhea, our study investigated a possible association between k. oxytoca and that disorder. | 2008 | 18808355 |
plasmid-borne arma methylase gene, together with blactx-m-15 and blatem-1, in a klebsiella oxytoca isolate from china. | an arma-producing klebsiella oxytoca isolate, strain 157, was detected after screening of 447 extended-spectrum beta-lactamase-producing enterobacteriaceae isolates in china. k. oxytoca 157 was resistant to aminoglycosides, ciprofloxacin and most beta-lactams. resistance to aminoglycosides and beta-lactams could be transferred to recipient escherichia coli by conjugation. arma, blactx-m-15 and blatem-1 genes were detected in k. oxytoca 157 and transconjugant e. coli strain 600(pec157). mutation ... | 2008 | 18809557 |
comparison of pfge and multilocus sequence typing for analysis of klebsiella pneumoniae isolates. | 2008 | 18809566 | |
high prevalence of plasmid-mediated quinolone resistance genes qnr and aac(6')-ib-cr in clinical isolates of enterobacteriaceae from nine teaching hospitals in china. | quinolone resistance is an emerging problem in china. to investigate the prevalence of the plasmid-mediated quinolone resistance genes qnr and aac(6')-ib-cr, a total of 265 clinical isolates of escherichia coli, klebsiella pneumoniae, citrobacter freundii, and enterobacter cloacae with ciprofloxacin mics of > or =0.25 microg/ml were screened at nine teaching hospitals in china. the qnra, qnrb, qnrs, and aac(6')-ib genes were detected by pcr. the aac(6')-ib-cr gene was further identified by diges ... | 2008 | 18809939 |
active metabolites from dunalia spinosa resinous exudates. | dunalia spinosa, a plant used in folk medicine for toothaches, breathing problems and cleansing wounds, was found active as antimicrobial and antioxidant. a new (e)-aurone rutinoside (dunaurone) has been isolated from the aerial parts of the plant, and its structure was determined by spectroscopic means. lupeol, beta-sitosterol, scopoletin, quercetin and withaferin a were also found. all the extracts exhibited strong antimicrobial activity while dunaurone showed only weak antimicrobial inhibitio ... | 2008 | 18810990 |
complete nucleotide sequence of pkp96, a 67 850 bp multiresistance plasmid encoding qnra1, aac(6')-ib-cr and blactx-m-24 from klebsiella pneumoniae. | the multiresistance plasmid pkp96 from klebsiella pneumoniae was sequenced completely and analysed concerning its genetic environment and distributing of antimicrobial resistance genes. | 2008 | 18812424 |
arrival of klebsiella pneumoniae producing kpc carbapenemase in the united kingdom. | kpc-type carbapenemases are increasingly prevalent in parts of the usa and israel and are an emerging concern in south america, europe and china. we investigated the uk's first two kpc-producing klebsiella pneumoniae isolates. | 2008 | 18812425 |
[ants in a hospital environment and its importance as vector of bacteria]. | the external ant community of hospital municipal de morrinhos, in morrinhos, goiás state, was characterized by the low rates of richness, diversity, dominance and equity of species abundance. pheidole sp.1, a polygynic species was numerically dominant in this environment, although it coexists with potentially competitive species. this ant species prevailed within all hospital departments and its space-time distribution was a little aggregated (variance/mean ratio = 1.102, chi2 = 29.38, p < 0.01) ... | 2008 | 18813751 |
[bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents--special references to bacteria isolated between april 2006 and march 2007]. | tendency of isolated bacteria from infections in abdominal surgery during the period from april 2006 to march 2007 were investigated in a multicenter study in japan, and the following results were obtained. in this series, 474 strains including 23 strains of candida spp. were isolated from 170 (75.2%) of 226 patients with surgical infections. two hundred and twenty-six strains were isolated from primary infections, and 224 strains were isolated from postoperative infections. from primary infecti ... | 2008 | 18814799 |
tigecycline in vitro activity against commonly encountered multidrug-resistant gram-negative pathogens in a middle eastern country. | the lack of data from the middle east warranted studying tigecycline in vitro activity in lebanon against consecutive multidrug-resistant (mdr) bacteria, including extended-spectrum beta-lactamases producing clinical isolates of escherichia coli (n = 150), klebsiella pneumoniae (n = 100), and acinetobacter spp. (n = 64) using the standard disk diffusion method. tigecycline-resistant and intermediate findings were as follows: e. coli, 0% and 0%; k. pneumoniae, 3% and 16%; and acinetobacter spp., ... | 2008 | 18814990 |
empiric treatment with once-daily cefonicid and gentamicin for febrile non-neutropenic pediatric cancer patients with indwelling central venous catheters. | summary: the approach to treating febrile non-neutropenic hematooncologic patients with central venous catheters varies. we recently introduced once-daily administration of cefonicid and gentamicin for such children who were in good clinical condition and without focal signs of infection. our 2-year experience of 125 episodes in 54 children is hereby reported. absolute neutrophil counts were 550 to 16,700/mm. bacteremia occurred in 6.4% episodes: only in patients with hickman/broviac catheters a ... | 2008 | 18797200 |
xla-associated neutropenia treatment: a case report and review of the literature. | x-linked agammaglobulinemia (xla) is a primary b-cell deficiency syndrome with an incidence of 5 to 10 cases per million. the current treatment approach includes intravenous immunoglobulin and aggressive antibiotic regimens for infections. besides recurrent infections, xla patients may present with other manifestations, such as alopecia, enteropathy, amyloidosis, and neutropenia. neutropenia, which has been shown in up to 25% of affected patients, might also contribute to the degree of severity ... | 2008 | 18799945 |
klebsiella oxytoca bacteremia causing septic shock in recipients of hematopoietic stem cell transplant: two case reports. | abstract: | 2008 | 18801186 |
liver abscess due to klebsiella pneumoniae showing the mucoid phenotype. | 2008 | 18801581 | |
removing bacteria from hospital surfaces: a laboratory comparison of ultramicrofibre and standard cloths. | we compared the ability of ultramicrofibre-woven cloths with conventional cloths moistened with water only, for their ability to remove several types of organisms relevant to hospital-acquired infections from a variety of surfaces in hospitals. we showed that ultramicrofibre cloths consistently outperformed conventional cloths in their decontamination ability, across all surfaces, and irrespective of whether the bacteria were coated on to the surfaces with phosphate-buffered saline (pbs) or pbs ... | 2008 | 18801594 |
wound healing, anti-microbial and antioxidant potential of dendrophthoe falcata (l.f) ettingsh. | dendrophthoe falcata (l.f) ettingsh (loranthaceae) of the order santalales, is used ethnomedicinally for treating ulcers, asthma, impotence, paralysis, skin diseases, and wounds. in this context, validations of the ethnotherapeutic claims of the plant in wound healing activity was studied, besides anti-microbial activity and antioxidant activity were performed to understand the mechanism of wound healing potency. the ethanolic extract of aerial parts of dendrophthoe falcata ethanolic extract (df ... | 2008 | 18790035 |
evolution of antimicrobial susceptibility patterns of aerobic and facultative gram-negative bacilli causing intra-abdominal infections: results from the smart studies 2003-2007. | study for monitoring antimicrobial resistance trends (smart) is an ongoing global antimicrobial surveillance program focused on clinical isolates from intra-abdominal infections (iai). the objective of this subanalysis was to assess the evolution of the antimicrobial susceptibility patterns among aerobic and facultative gram-negative bacilli (gnb) recovered over a 5-year period at our institution. we tested the in vitro activity of the antimicrobials, commonly used to treat iai, against consecut ... | 2008 | 18792817 |
[in vitro generation of mutants of klebsiella pneumoniae following exposure to fluorquinolones. relationship with the presence of extended spectrum betalactamases]. | in order to provide data that may help to explain the relationship between production of extended spectrum betalactamases and fluorquinolone resistance in klebsiella pneumoniae, we have developed an in vitro model of exposure to sub-inhibitory concentrations of various fluorquinolones (ciprofloxacin, levofloxacin and moxifloxacin) in two strains, one of which is a producer of extended spectrum betalactamases (esbl). our data show that mutants with reduced fluorquinolone susceptibility appear in ... | 2008 | 18792819 |
the role of diabetes mellitus in patients with bloodstream infections. | since diabetes mellitus predisposes to infection, we evaluated whether diabetes increases the risk of bloodstream infection and worsens its outcome. | 2008 | 18792825 |
impact of empiric antimicrobial therapy on outcomes in patients with escherichia coli and klebsiella pneumoniae bacteremia: a cohort study. | it is unclear whether appropriate empiric antimicrobial therapy improves outcomes in patients with bacteremia due to escherichia coli or klebsiella. the objective of this study is to assess the impact of appropriate empiric antimicrobial therapy on in-hospital mortality and post-infection length of stay in patients with escherichia coli or klebsiella bacteremia while adjusting for important confounding variables. | 2008 | 18793400 |
an unusual case of xanthogranulomatous pyelonephritis in a leukemia patient. | we report a 65-year-old woman with leukemia who presented with urinary tract infection, splenic abscess, and a renal mass. both urine and pus culture of the splenic abscess yielded klebsiella pneumoniae. the differential diagnosis of the renal mass by radiological findings included unliquefied renal abscess, xanthogranulomatous pyelonephritis, and renal cell carcinoma. percutaneous biopsy of the renal mass confirmed the diagnosis of xanthogranulomatous pyelonephritis. because of high surgical ri ... | 2008 | 18793569 |
a prospective study of ceftriaxone treatment in acute pyelonephritis caused by extended-spectrum beta-lactamase-producing bacteria. | much controversy exists as to whether cephalosporin treatment is appropriate for infections caused by esbl-producing organisms because no randomized controlled studies have been performed. | 2008 | 18788687 |
comparative in vitro activity of tigecycline against enterobacteria producing two or more extended-spectrum beta-lactamases. | 2008 | 18789848 | |
computational redesign of the shv-1 beta-lactamase/beta-lactamase inhibitor protein interface. | beta-lactamases are enzymes that catalyze the hydrolysis of beta-lactam antibiotics. beta-lactamase/beta-lactamase inhibitor protein (blip) complexes are emerging as a well characterized experimental model system for studying protein-protein interactions. blip is a 165 amino acid protein that inhibits several class a beta-lactamases with a wide range of affinities: picomolar affinity for k1; nanomolar affinity for tem-1, sme-1, and blai; but only micromolar affinity for shv-1 beta-lactamase. the ... | 2008 | 18775544 |
[aminoglycosides and colistin inhibit biofilm formation in klebsiella pneumoniae]. | to evaluate the effect of subinhibitory concentrations (sub-mics) of amikacin, tobramycin and colistin on biofilm formation, surface hydrophobicity, lipase activity and response to oxidative stress in two clinical k. pneumoniae strains. | 2008 | 18767377 |
bacterial communities on electron-beam pt-deposited electrodes in a mediator-less microbial fuel cell. | the content of a bacterial consortium found on an electron beam (e-beam) pt-deposited electrode in a mediator-less microbial fuel cell (mfc) using glucose and glutamate as fuel is reported in this paper. the e-beam pt-deposited electrode and electrochemically active bacteria (eab) consortium were developed to improve the mediator-less mfc performance. denaturing gradient gel electrophoresis (dgge), restriction fragment length polymorphism (rflp), and 16s rrna sequencing were used to identify the ... | 2008 | 18767694 |
pandrug-resistant klebsiella pneumoniae, pseudomonas aeruginosa and acinetobacter baumannii infections: characteristics and outcome in a series of 28 patients. | we describe the characteristics and outcome of pandrug-resistant (pdr) gram-negative bacterial infections (23 klebsiella pneumoniae isolates, 3 pseudomonas aeruginosa and 3 acinetobacter baumannii) of hospitalised patients at a tertiary-care centre (1 january 2006-31 may 2007). the site of infection was central venous catheter-related in 5 of 24 patients with clinical infection, bacteraemia in 5, the respiratory system in 5, surgical site in 5, the urinary system in 2, the ascitic fluid in 1 and ... | 2008 | 18768302 |
ruptured hepatic abscess mimicking perforated viscus. | in the majority of pneumoperitoneum cases we diagnose perforated viscus. we present herein a case of ruptured hepatic abscess mimicking perforated viscus. | 2008 | 18768341 |
first occurrence of kpc-2-possessing klebsiella pneumoniae in a greek hospital and recommendation for detection with boronic acid disc tests. | to investigate the first kpc carbapenemase-producing klebsiella pneumoniae isolate from a greek hospital, including phenotypic methods to aid recognition of this resistance type. | 2008 | 18772158 |
gene cloning, protein purification, and enzymatic properties of multicopper oxidase, from klebsiella sp. 601. | a gene encoding a putative multicopper oxidase (mco) was cloned from the soil bacterium klebsiella sp. 601 and its corresponding enzyme was overexpressed in an escherichia coli strain. klebsiella sp. 601 mco is composed of 536 amino acids with a molecular mass of 58.2 kda. theoretical calculation gave a pi value of 6.11. the amino acid sequence of klebsiella sp. 601 mco is strongly homologous to that of e. coli cueo with a similarity of 90% and an identity of 78%. unlike e. coli cueo, klebsiella ... | 2008 | 18772935 |
[the analysis of the bacterial and fungal flora in maxillary sinuses in patients operated due to fess method]. | the aim of this work was to analyse the bacterial and fungal flora in maxillary sinuses in patients operated due to the fess method. | 2008 | 18837224 |
[antibacterial activity of lactic acid bacteria community sfc-2 used for fermentation of air-dried crop straws]. | to evaluate the antibacterial activity of lactic acid bacteria community sfc-2 in fermented crop straw. | 2008 | 18837364 |
in vitro activity of tigecycline and occurrence of tetracycline resistance determinants in isolates from patients enrolled in phase 3 clinical trials for community-acquired pneumonia. | the in vitro activity of tigecycline was evaluated against baseline pathogens isolated from patients enrolled in phase 3 clinical trials for community-acquired pneumonia conducted in 29 countries worldwide. tigecycline was active against the most prevalent pathogens, including streptococcus pneumoniae (mic(90) 0.06 mg/l), staphylococcus aureus (mic(90) 0.25 mg/l), haemophilus influenzae (mic(90) 0.5 mg/l) and klebsiella pneumoniae (mic(90) 1 mg/l). twelve isolates of s. pneumoniae expressing tet ... | 2008 | 18844692 |
oxacillinase-mediated resistance to carbapenems in klebsiella pneumoniae from lebanon. | 2008 | 18844693 | |
renal abscess in children: a 10-year clinical and radiologic experience in a tertiary medical center. | renal abscess is a rare disease in childhood and early diagnosis is essential to minimize the renal damages. experiences gained from this 10-year study on patients with ct-proved diagnosis include the varied clinical presentations and use of sonographic-marked nephromegaly and focal mass as indications for further ct diagnosis. | 2008 | 18845984 |
multiresistant enterobacteriaceae: new threat of an old problem. | the enterobacteriaceae are among the most important causes of serious nosocomial and community-onset bacterial infections in humans, and resistance to antimicrobial agents in these species has become an increasingly relevant problem for healthcare providers. beta-lactam and fluoroquinolone antibiotics are important drug classes used to treat infections caused by enterobacteriaceae. emerging resistance mechanisms against these agents have recently been described in enterobacteriaceae and include ... | 2008 | 18847404 |
clinical significance of extended-spectrum beta-lactamases. | the spread of extended-spectrum beta-lactamases (esbls) in nosocomial and community-acquired enterobacteria is an important challenge for clinicians as the therapeutic options for these organisms are limited. the emergence of esbl-producing escherichia coli in the community, associated with the spread of ctx-m esbl, is one of the most significant epidemiologic changes in infectious diseases during recent years. the epidemiology of these infections is complex and combines the expansion of mobile ... | 2008 | 18847405 |
[recent evolution and characterization of extended-spectrum beta-lactamase producing enterobacteria in the chu of nice (2005-2007)]. | esbl producing enterobacteria (e-esbl+) are always a public health concern, mainly due to increase of ctx-m beta-lactamase. so, 542 new strains were isolated in the chu de nice during the 2005-2007 period. the aim of this work was to characterize the esbl and to type isolates suspected to be implicated in outbreaks. | 2008 | 18848404 |
in vivo pharmacokinetics of a gentamicin-loaded collagen sponge in acute periprosthetic infection: serum values in 19 patients. | the in vivo pharmacokinetics of gentamycin- loaded collagen fleeces in humans have not been described in the current literature. we therefore analyzed in vivo pharmacokinetics of these fleeces when used in the treatment of periprosthetic infections. | 2008 | 18839370 |
microflora of bile aspirates in patients with acute cholecystitis with or without cholelithiasis: a tropical experience. | the current study determined the spectrum of biliary microflora with special emphasis on enteric fever organisms in patients with acute cholangitis with and without cholelithiasis or other biliary diseases. the patients were divided into three groups: group a consisted of patients with acute cholecystitis with cholelithiasis; group b consisted of patients with acute cholecystitis with gastrointestinal ailments requiring biliary drainage and group c consisted of patients with gallbladder carcinom ... | 2008 | 18839486 |
clinicobacteriological study of chronic dacryocystitis in adults. | chronic dacryocystitis is the inflammation of lacrimal sac, frequently caused by bacteria. obstruction of nasolacrimal duct converts the lacrimal sac a reservoir of infection. it is a constant threat to cornea and orbital soft tissue. moreover, it causes social embarrassment due to chronic watering from the eye. this study was conducted to find out the current clinicobacteriological profile of chronic dacryocystitis in adults. a total of 56 adult patients were selected from ophthalmology opd. de ... | 2008 | 18839635 |
the molecular epidemiology of extended-spectrum beta-lactamase producing organisms. | 2008 | 18842233 | |
[characterization and molecular epidemiology of esbl in escherichia coli and klebsiella pneumoniae in 11 spanish hospitals (2004)]. | the epidemiological distribution of extended-spectrum beta-lactamase (esbl) types in escherichia coli and klebsiella pneumoniae was evaluated in various hospitals in spain and compared with previous studies. | 2008 | 18842234 |
[fluoroquinolones and gram-negative bacteria: antimicrobial activity and mechanisms of resistance]. | fluoroquinolones acts by interacting with type ii topoisomerases (dna gyrase and topoisomerases iv). related to this mechanism of action, bacteria have developed resistance mechanisms consisting in some target mutations (gyra/gyrb for dna gyrase and parc/pare for topoisomerase iv) or in a reduced access to the target itself, by either decreased permeability or augmented expression of efflux pumps, such as acrab and mexab. along with these classical mechanisms of chromosomal resistance, the prese ... | 2008 | 18843219 |
milk production change following clinical mastitis and reproductive performance compared among j5 vaccinated and control dairy cattle. | naturally occurring cases of bovine clinical mastitis (cm) were studied among j5 vaccinates and controls on 3 commercial dairy farms. milk production change and reproductive performance following cm were compared between the 2 groups. among 306 controls and 251 vaccinates, there were 221 new cases of cm affecting 120 cows; 437 lactations never had a case of cm. environmental pathogens made up 90% (159/176) of etiologic agents isolated. change in daily milk production following cm was associated ... | 2008 | 18832209 |
cleanliness scores as indicator of klebsiella exposure in dairy cows. | this study was designed to explore the relationship between cow and udder cleanliness scores and the risk of isolation of klebsiella spp. from lower hind legs and teat ends, respectively. the distribution of klebsiella species was compared among isolates from teat ends, legs, and cases of clinical mastitis obtained from 2 dairy farms in new york state, with 850 and 1,000 cows, respectively. farms were visited twice approximately 4 wk apart in august and september 2007 to obtain cleanliness score ... | 2008 | 18832213 |
mast cell il-6 improves survival from klebsiella pneumonia and sepsis by enhancing neutrophil killing. | the pleiotropic cytokine il-6 has favorable and harmful effects on survival from bacterial infections. although many innate immune cells produce il-6, little is known about relevant sources in vivo and the nature of its contributions to host responses to severe bacterial infections. to examine these roles, we subjected mast cell-specific il-6-deficient mice to the cecal ligation and puncture model of septic peritonitis, finding that survival in these mice is markedly worse than in controls. foll ... | 2008 | 18832718 |
pyogenic liver abscess as endemic disease, taiwan. | pyogenic liver abscess has become a health problem in taiwanese society. however, the extent of this problem has remained unclear because of the lack of a population-based study. we therefore performed a nationwide analysis of pyogenic liver abscess in taiwan from 1996 through 2004. we analyzed 29,703 cases from the taiwan national health insurance database and 506 cases from national taiwan university hospital. our analysis showed that the annual incidence of pyogenic liver abscess increased st ... | 2008 | 18826824 |
new organoselenium compounds active against pathogenic bacteria, fungi and viruses. | different n-substituted benzisoselenazol-3(2h)-ones, analogues of ebselen were designed as new antiviral and antimicrobial agents. we report their synthesis, chemical properties as well as study on biological activity against broad spectrum of pathogenic microorganisms (staphylococcus aureus, staphylococcus simulans, escherichia coli, pseudomonas aeruginosa, klebsiella pneumoniae, candida albicans, aspergillus niger) and viruses (herpes simplex virus type 1 (hsv-1), encephalomyocarditis virus (e ... | 2008 | 18827382 |
causative agents of urinary tract infections in children and their antibiotic sensitivity pattern: a hospital based study. | a retrospective study was conducted to find out the causative agents of urinary tract infection (uti) in children and their antibiotic sensitivity pattern among nepalese children. this was done at kanti children's hospital in kathmandu (nepal) by analyzing the records of urine samples collected for culture and sensitivity tests over a period of six months (april to november, 2007). of the total 1878 mid-stream urine samples collected from suspected cases of uti, 538 (28.6%) were positive for pat ... | 2008 | 18828428 |
distribution frequency of pathogenic bacteria isolated from cutaneus leishmaniasis lesions. | cutaneous leishmaniasis (cl) is a parasitic disease characterized by single or multiple ulcerations. secondary bacterial infections are one of the complications that can increase the tissue destruction and the resulting scar. to better determine the incidence of real secondary bacterial infections in cl, we designed the current study. this was a cross-sectional study performed in skin diseases and leishmaniasis research centre, isfahan, iran. a total of 1,255 patients with confirmed cl enrolled ... | 2008 | 18830062 |
fournier's gangrene: is it scrotal gangrene? | fournier's gangrene was originally described as scrotal gangrene in young males. today, it is generally accepted as synergistic necrotizing fasciitis of perineal, genital, or perianal regions, and the epidemiologic data have changed. however, there are still limited data about females due to the lack of female patients, even in large case series. | 2008 | 18821069 |
artificial binding proteins (affitins) as probes for conformational changes in secretin puld. | the dna-binding protein sac7d was previously modified to bind with high affinity to the n domain of the outer membrane secretin puld from the bacterium klebsiella oxytoca. here, we show that binding of the sac7d derivatives (affitins) to puld is sensitive to conformational changes caused by denaturant and by the zwitterionic detergent zwittergent 3-14 routinely used to extract secretins from outer membranes. this sensitivity to the conformational state of puld allowed us to use the affitins as p ... | 2008 | 18822295 |
[active forms of oxygen as a factor regulating surface characteristics of bacterial cells]. | effects of sublethal concentration of active forms of oxygen (hydrogen peroxide and hydroxyl radical) on cell surface properties of escherichia coil, staphylococcus aureus, bacillus subtilis, and klebsiella pneumoniae were studied. | 2008 | 18822495 |
[protective activity of secreted proteins of streptococcus pneumoniae and klebsiella pneumoniae]. | protective efficacy of secreted proteins of streptococcus pneumoniae and klebsiella pneumoniae cultivated on cardiocerebral broth and semisynthetic growth medium respectively was studied in vivo. fraction with molecular weight 30 - 50 kda obtained by the method of membrane fractionation had high protective efficacy. two-dose immunization of mice with this fraction provided 80 - 100% protection from infection by homologous strains of s. pneumoniae and k. pneumoniae. cross-protective activity of t ... | 2008 | 18822497 |
[nosocomial meningitis with dual agents and treatment with intraventricular gentamicin]. | nosocomial central nervous system infections constitute 0.4% of all nosocomial infections. the responsible pathogens of nosocomial meningitis are quite different from community-acquired meningitis with high rates of morbidity and mortality. the most important prognostic factor is the appropriate choice of pathogen-specific antibacterial therapy. in this report, a 64 years old woman with nosocomial meningitis caused by klebsiella pneumoniae and acinetobacter spp. after lumbar disc hernia operatio ... | 2008 | 18822895 |
the structure of urease activation complexes examined by flexibility analysis, mutagenesis, and small-angle x-ray scattering. | conformational changes of klebsiella aerogenes urease apoprotein (ureabc)(3) induced upon binding of the ured and uref accessory proteins were examined by a combination of flexibility analysis, mutagenesis, and small-angle x-ray scattering (saxs). proflex analysis of urease provided evidence that the major domain of ureb can move in a hinge-like motion to account for prior chemical cross-linking results. rigidification of the ureb hinge region, accomplished through a g11p mutation, reduced the e ... | 2008 | 18823937 |
synthesis of the trisaccharide repeating unit related to klebsiella 012 serotype. | synthesis of the trisaccharide, allyl alpha-l-rhamnopyranosyl-(1-->3)-2-acetamido-2-deoxy-beta-d-glucopyranosyl-(1-->4)-alpha-l-rhamnopyranoside related to o-chain glycans isolated from the deaminated lpss of klebsiella pneumoniae serotype 012, was achieved through condensation of suitably synthesized disaccharide, allyl 4,6-o-benzylidene-2-deoxy-2-phthalimido-beta-d-glucopyranosyl-(1-->4)-2,3-di-o-benzoyl-alpha-l-rhamnopyranoside and donor, ethyl 2,3,4-tri-o-acetyl-1-thio alpha-l-rhamnopyranosi ... | 2008 | 18804201 |
pyogenic liver abscess: clinical profile, microbiological characteristics, and management in a hong kong hospital. | pyogenic liver abscess (pla) is a major hepatobiliary infection with a significant mortality rate of 10% to 25%. over the past 2 decades, there have been significant developments in the management of this disease. this study describes the demographic, clinical, and microbiological features, management, and poor prognostic factors of pla in hong kong. | 2008 | 19255692 |
[antimicrobial resistance of the bacteria isolated from blood cultures in 2007]. | antimicrobial resistance become emerging global problem. particularly dramatic increase in the number and type of bacteria resistant to numerous and structurally different antibiotics has taken place in the last two decades. | 2008 | 19256064 |
rates of antimicrobial resistance in latin america (2004-2007) and in vitro activity of the glycylcycline tigecycline and of other antibiotics. | as a part of the tigecycline evaluation and surveillance trial (t.e.s.t.), gram-positive and gram-negative bacterial isolates were collected from 33 centers in latin america (centers in argentina, brazil, chile, colombia, guatemala, honduras, jamaica, mexico, panama, puerto rico, and venezuela) from january 2004 to september 2007. argentina and mexico were the greatest contributors of isolates to this study. susceptibilities were determined according to clinical laboratory standards institute gu ... | 2008 | 19219281 |
inadequate timing between corticosteroid and antibiotics applications increases mortality due to sepsis. | this study tested the hypothesis that the use of corticosteroids prior to antibiotics can lower the mortality rate in severe infections by s. aureus or gram-negative bacilli, using an animal model. this study was a prospective and controlled study, placed in a university laboratory. seven hundred and sixty mice distributed into three groups (staphylococcus aureus, escherichia coli and klebsiella pneumoniae infected). the interventions in each group were: i) infection control (intra-peritoneal); ... | 2008 | 19219282 |
[bacterial etiology of the conditions associated with bacteremia/septicemia during the years 2006-2007]. | evaluation of the etiology of bacterial diseases associated with bacteremia/ sepsis in the emergency county hospital of tg. mureş during 2006-2007. | 2008 | 19241994 |
[cumulative antibiogram--means of following local resistance phenomena based on material gathered in the laboratory of microbiology]. | the cumulative antibiogram (ca) represents a report which summarizes the susceptibility of commonly isolated microorganisms to usual antibiotics in a defined period of time. we have evaluated the local resistance data during the year 2007 by generating ca from the bacteriology laboratory's database in mures county emergency clinical hospital for 3 categories of microorganisms: gram-positive cocci, gram-negative enteric rods and non-fermenters. a total of 1382 individual antibiotic susceptibility ... | 2008 | 19241995 |
antimicrobial activity of some macrophytes from lake manzalah (egypt). | the antimicrobial activities of aqueous and organic solvents (chloroform, ethanol and methanol) extracts of four plants ceratophyllum demersum l., eichhornia crassipes, potamogeton crispus and potamogeton pectinatus were tested in vitro against seventeen different microorganisms including gram-positive and gram-negative bacteria and fungi. nine of these identified organisms were obtained from different sources, bacillus subtilis 1020, bacillus cereus 1080, staphylococcus aureus, erwinia carotovo ... | 2008 | 19205264 |
re-usable low density polyethylene arm glove for puerperal intrauterine exploration. | to design a long arm glove that can be used within a puerperal uterus to prevent the health-care worker contracting hiv from an infected patient. the designed long arm glove should be cheap (affordable) and readily available in low resource centres and must have proven sterility assurance and tensile strength to confer protection for the health worker. | 2008 | 19133425 |
[modification of bacterial population structure on anti-lysozyme activity under the influence of hexylresorcinol]. | to investigate the modifying effect of hexylresorcinol chemical analog on anti-lysozyme activity of bacteria. | 2008 | 19189462 |
peritoneal dialysis-related peritonitis in the years 2005-2007 among patients of the peritoneal dialysis clinic of the department of nephrology, transplantology and internal medicine, pomeranian medical university in szczecin. | peritoneal dialysis-related peritonitis (pdrp) is the most common complication of dialysis in patients undergoing continuous ambulatory peritoneal dialysis. | 2008 | 19202946 |
[current bacterial causes of osteomyelitis in children with sickle cell disease]. | introduction: osteomyelitis in children with sickle cell disease has been caused mainly by salmonella species, but in recent years, greater variation has resulted in other bacteria sometimes heading this list. we conducted this survey to determine the present distribution of causative bacteria, to improve initial probabilistic antibiotic therapy. | 2008 | 19188128 |
[multiple antibiotic resistance of associative microflora during urogenital pathology]. | susceptibility of associative microflora isolated from patients with inflammatory diseases of urogenital tract was investigated. etiologic structure of the diseases and cross-resistance to antibiotics of escherichia coli, staphylococcusaureus, and klebsiella pneumoniae strains isolated from women with endocervicitis and men with urethritiswas assessed. ciprofloxacin and gentamycin had the highest activity, whereas beta-lactam antibiotics were mildly active. isolated strainswere resistant to macr ... | 2008 | 19186554 |
[emergence of 16s rrna methylase gene rmtb in klebsiella pneumoniae isolates from the inpatients in zhejiang province, china]. | to investigate the presence and genetic background of 16s rrna methylase gene and aminoglycoside modifying enzymes (ames) genes in klebsiella pneumoniae isolated from the people's liberation army 98th hospital, huzhou district, zhejiang province, china. | 2008 | 19173857 |
[isolation, identification and 16s rdna phylogenetic analysis of klebsiella pneumonia from diarrhea specimens]. | to understand the biochemical characteristics and 16s rdna genetic sequence evolution of strains isolated from diarrhea specimens so as to provide basis for classification and identification of klebsiella pneumoniae. | 2008 | 19173969 |
[application of nano-sized tio2 photocatalysis to air purification and sterilization]. | to develop and evaluate the efficiency of air purification and sterilization instrument based on nano-sized tio(2) photocatalytic technique. | 2008 | 19176145 |
[resistance to newer beta-lactams and related esbl types in gram-negative nosocomial isolates in turkish hospitals: results of the multicentre hitit study]. | increasing resistance due to extended-spectrum beta-lactamases (esbls) and multiple resistance mechanisms in gram-negative hospital isolates restrict the role of beta-lactam antibiotics in empirical treatment of serious infections. as the prevalence of esbl producing strains and resistance rates to antimicrobial agents can vary in each center, local surveillance studies are required to guide therapy. in this study, in vitro rates of resistance to ceftriaxone, ceftazidime, cefepime, imipenem, cef ... | 2008 | 19149074 |
[investigation of plasmid-mediated ampc beta-lactamase types in klebsiella spp. and escherichia coli isolates resistant or intermediate to cefoxitin]. | plasmid mediated ampc beta-lactamases are reported from enterobacteriaceae with increasing frequency. there have been reports of treatment failures in patients infected with these organisms and given broad-spectrum cephalosporins. the aim of this study was to investigate the presence of plasmid mediated ampc beta-lactamases in escherichia coli and klebsiella spp. a total of 41 strains of cefoxitin resistant or intermediate e. coli (n= 27) and klebsiella spp. (n= 14) were collected from january 2 ... | 2008 | 19149075 |
[antibiotic resistance rates of extended spectrum beta-lactamase producing escherichia coli and klebsiella spp. strains isolated from urinary tract infections in a private hospital]. | the aim of this study was to detect the antibiotic resistance rates of extended spectrum beta-lactamase (esbl) producing escherichia coli and klebsiella spp. strains isolated from urinary tract infections (utis) in private acibadem hospital, istanbul, turkey. a total of 1100 e. coli and 356 klebsiella spp. strains isolated from 17.028 urine cultures which were processed between october 2006 and august 2007 in the clinical laboratory, were included to the study. identification of bacteria and ant ... | 2008 | 19149097 |
tem & shv genes in extended spectrum beta-lactamase producing klebsiella species beta their antimicrobial resistance pattern. | extended spectrum beta-lactamases (esbls) are often plasmid mediated derived from mutations in the classic tem and shv genes by one or more amino acid substitution around the active site. detection of tem and shv genes by molecular methods in esbl producing bacteria and their pattern of antimicrobial resistance can provide useful information about its epidemiology and risk factors associated with these infections. we investigated the presence of tem and shv genes in esbl producing klebsiella spp ... | 2008 | 19246801 |
in-vitro bioactivity of venda medicinal plants used in the treatment of respiratory conditions. | infectious diseases, especially those affecting the respiratory tract, represent a critical problem to health. crude methanol and water extracts of 10 venda plants reported to be used ethnomedically in the treatment of respiratory conditions were assessed for their antimicrobial activity against standard strains and clinical isolates of candida albicans, haemophilis influenzae, klebsiella pneumoniae, staphylococcus aureus, streptococcus pneumoniae, and mycobacterium smegmatis using the disc diff ... | 2008 | 19244294 |
bacterial indicators of pollution of the douala lagoon, cameroon: public health implications. | indiscriminate disposal of untreated wastes which are often heavily laden with sewage microorganisms some of which are pathogenic to humans into aquatic environments near cities could serve as potential dangers to human health. | 2008 | 19357756 |
phenotypic detection and occurrence of extended-spectrum beta-lactamases in clinical isolates of klebsiella pneumoniae and escherichia coli at a tertiary hospital in trinidad & tobago. | the incidence and distribution of esbl producing microorganisms such as e. coli and k. pneumoniae have been demonstrated and varies in different health care facilities and as well as other countries this study was carried out to determine the frequency of occurrence and the antimicrobial susceptibility pattern of esbl producing e. coli and k. pneumoniae species from clinical isolates at a tertiary hospital in trinidad & tobago. standard microbiological procedures and automated microscan system w ... | 2008 | 19287841 |
[influence of sub-mics of selected antibiotics on hydrophobic and adhering properties of klebsiella pneumoniae strains isolated from urine samples]. | the aim of this study was to evaluate the effects of sub-mics of selected antinbiotics on hydrophobic and adhering properties of klebsiella pneumoniae rods. cefotaxime, gentamicin, ciprofloxacin and tetracycyline were used. the hydrophobicity was evaluated according to the method of rosenberg et al. the adhering properties were estimated by method of christensen et al. the exposure of k. pneumoniae strains to submics of antibiotics reduced hydrophobicity and adhesion to polystyrene. all antibiot ... | 2008 | 19382601 |
[antimicrobial resistance profile of e. coli and klebsiella spp. from urine in the infectious diseases hospital iaşi]. | the increasing frequency of extended-spectrum beta-lactamases (esbls) producing enterobacteriaceae among nosocomial and community-acquired infections is an important problem for both microbiologists and clinicians, because of the difficulty in correctly detecting, reporting and treating such infections. results: in the clinical hospital of infectious diseases iaşi the most frequent etiological agents of urinary tract infections were: e. coli - 64%, klebsiella spp. 11% and enterococcus spp - 5%. ... | 2008 | 19295023 |
antibacterial profile of fermented seed extracts of ricinus communis: findings from a preliminary analysis. | the study was carried out to ascertain the antibacterial properties inherent in fermented seed extracts of ricinus communis. dry seeds of r. communis (castor oil plant) were deshelled, grounded to powder, fermented, and then extracted both with alcohol and water using soxhlet machine. different concentrations of the extracts were tested against selected bacteria using diffusion method of susceptibility testing on sensitivity testing agar medium. klebsiella pneumoniae, escherichia coli, proteus v ... | 2008 | 19434215 |