Publications

role of iron in the pathogenesis of vibrio vulnificus infections.	infections with vibrio vulnificus resulting in septicemia and high mortality have been correlated with pre-existing liver disease and hemochromatosis. as these conditions are associated with impaired iron metabolism and as iron availability in the host has been implicated in the pathogenicity of a number of bacterial infections, the role of iron as a possible factor in the pathogenesis of v. vulnificus was examined. injection of mice with iron resulted in a lowering of the 50% lethal dose from 1 ...	1981	7309236
vibrio vulnificus (lactose-positive vibrio) and vibrio parahaemolyticus differ in their susceptibilities to human serum.	eleven vibrio vulnificus (lactose-positive vibrio) strains were less susceptible to the bactericidal activity of normal human serum or serum treated with magnesium-ethyleneglycol-bis (beta-aminoethyl ether)-n,n'-tetraacetic acid than were six vibrio parahaemolyticus strains.	1981	6788703
detection of extracellular toxin(s) produced by vibrio vulnificus.	conditions are described for the production, in high titers, a heat-labile, antigenic, extracellular toxin(s) by vibrio vulnificus, a recently recognized human pathogen. bacteriologically sterile culture filtrate preparations obtained from mid-logarithmic-phase cultures of the bacterium possessed cytolytic activity against mammalian erythrocytes, cytotoxic activity for chinese hamster ovary cells, vascular permeability factor activity in guinea pig skin, and lethal activity for mice. the specifi ...	1981	7024134
prevention and therapy of serous otitis media by oral decongestant: a double-blind study in pediatric practice.	we studied the efficacy of (1) preventing the development of serous otitis media (som) by using an oral decongestant in children with acute otitis media and (2) treating som with an oral decongestant. in a randomized double-blind study, 190 children were treated for acute otitis media with antibiotics and either pseudoephedrine hydrochloride (sudafed) or placebo. they were evaluated two weeks later by tympanometry and (independently) by clinical evaluation and pneumotoscopy. there were no signif ...	1981	351537
primary nursing: one nurse--one client planning care together.		1981	243765
effect of osteotropic hormones on cartilage metabolism.		1979	218877
transcription of endogenous c-type viruses in resting and proliferating tissues of balb/mo mice.		1979	228474
isolation of foot-and-mouth disease virus messenger rna from membrane-bound polyribosomes and characterization of its 5' and 3' termini.		1979	228483
guinea pig very low density lipoproteins are a good substrate for lipoprotein lipase.	in contrast to plasma from most other animals, guinea pig plasma causes little or no stimulation of lipoprotein lipase activity. very low density lipoproteins (vldl) isolated by ultracentrifugation of guinea pig serum caused a definite stimulation of lipase activity, whereas the infranatant inhibited the activity. gel filtration in 5 m guanidinium hydrochloride of delipidated vldl demonstrated that the activation was caused by a low molecular weight protein. the vldl themselves were hydrolized a ...	1979	229910
studies on the isolation and characterization of theilerial antigens: particularly on the applicability to passive hemagglutination test.		1979	261988
immunochemical properties of oligosaccharide-protein conjugates with klebsiella-k2 specificity. i. specificity and crossreactivity of anti-conjugate versus anti-bacterial antibodies.		1979	86152
cytofluorometric and cytochemical comparisons of normal and abnormal human cells from the female genital tract.	acridine orange staining of exfoliated cells from epithelial tissues facilitates discrimination between normal and abnormal cells: abnormal cells develop highly elevated nuclear fluorescence. comparisons of acridine orange (ao) staining with propidium iodide (pi) or feulgen staining have shown that: (a) pi staining also provides highly elevated nuclear fluorescence from abnormal cells; (b) the distributions of nuclear fluorescence following ao or pi staining were usually not significantly differ ...	1979	86579
the puzzle of "urethral syndrome": a possible answer?	82 strains of slow-growing, co2-dependent, gram-positive organisms have been isolated from the urine of 9 male and 73 female patients. 100% of the men and 93% of the women had urinary symptoms at the time of isolation, and 66% of the specimens showed pyuria. these organisms might account for the urinary symptoms of some patients previously diagnosed as having "urethral syndrome". preliminary data show that, if appropriate antibacterial treatment is given, most of these patients become symptom-fr ...	1979	86778
the role of p23,30-bearing human macrophages in antigen-induced t lymphocyte responses.		1979	88270
analysis of antigens in mycobacterium paratubercuolsis.		1979	90456
antigenic correlation between rat brain synaptic vesicles and rat bone marrow b lymphocytes.	rabbit anti-rat brain synaptic vesicle serum reacted with thymocytes and b lymphocytes in cytotoxicity and immunofluorescence assays. quantitative absorption analysis revealed that this antiserum contained antibodies specific for antigenic determinants on the surface membrane of a subpopulation of rat bone marrow b lymphocytes.	1979	91533
generation of a fibroblast chemotactic factor in serum by activation of complement.	when serum complement is activated by either the classical or alternative pathways, a factor with an apparent 80,000 mol wt is generated that is chemotactic for human dermal fibroblasts. the origin of this serum-derived chemotactic factor (sdcf) is not known; however, it may be a cleavage product from c5 because it is inactivated by monospecific antiserum to human c5, and it is not generated when the complement system is activated in human serum deficient in c5. sdcf is not chemotactic for human ...	1979	91624
human lung tumor-associated antigens of 32,000 daltons molecular weight.	lung tumor-associated antigens of approximately 32,000 daltons were recognized by the use of sensitive radioimmunoassays and rabbit antisera, one raised against an extract of pooled human malignant lung tissues and another raised against a cell line derived from a human squamous cell carcinoma of the lung. these antigens differ from antigens described previously, including carcinoembryonic antigen and alpha-fetoprotein. the antigens were detected on 13 of 13 lung tumors (of all histologic types) ...	1979	91695
human lung tissue and anaphylaxis:cyclic nucleotide response and prostaglandin synthesis.		1979	91946
changes in skin collagen polarization-optical properties after contact burn.		1979	92128
[cutaneous leishmaniasis. alcoy: an endemic zone].		1979	92178
[response to catecholamines in rats deficient in essential fatty acids (proceedings)].		1979	92240
suramin: a potent inhibitor of the reverse transcriptase of rna tumor viruses.	suramin--a well-known antitrypanosomal agent--was found to exert a strong inhibitory effect on the rna-directed dna polymerase (reverse transcriptase) activity of several oncornaviruses such as moloney murine leukemia virus, murine rauscher leukemia viruses, moloney murine sarcoma virus and avian myeloblastosis virus. inhibition of enzyme activity was obtained with both endogenous viral rna and (a)n . oligo(dt) as the template-primer. suramin effected a 50% inhibition of the reverse transcriptas ...	1979	92362
fetotoxicity and cataractogenicity of mirex in rats and mice with notes on kepone.		1979	92402
study on the significance of bronchial hyperreactivity in the bronchus obstruction after inhalation of cat dander allergen.	the role of bronchial hyperreactivity in the process that leads to bronchial obstruction after inhalation of an allergen was investigated. in 30 asthmatic children selected because of a positive skin test to cat dander allergen, we measured the histamine threshold, the reaction after allergen inhalation, the allergen-specific ige concentration in serum, the lowest allergen concentration to which the intracutaneous skin test was positive (skin titer), and the histamine release of leukocytes after ...	1979	92487
macrophage oxygen-dependent antimicrobial activity. i. susceptibility of toxoplasma gondii to oxygen intermediates.	a sensitive method for evaluating extracellular parasite viability was used to determine the in vitro susceptibility of virulent toxoplasma gondii to selected oxygen intermediates. by acridine orange fluorescent staining criteria, toxoplasmas were resistant to up to either 10(-3) m reagent h2o2 or h2o2 generated by glucose-glucose oxidase. in keeping with a lack of sensitivity to h2o2, toxoplasmas contained endogenous catalase (5.7 x 10(-4) baudhuin units/10(6) organisms). the addition of a pero ...	1979	92521
the zinc iodide-osmium (zio) reaction in the central nervous system: localization and relations to functional activity.	the fine structural characteristics of zio reaction was studied in the cerebral and cerebellar cortex and olfactory bulb of the rat and in synaptosomes prepared from rat cerebellar cortex. it was concluded that: 1. organelles of different nerve cell types exhibit different zio reactions provided that the impregnation was carried out under standardized conditions. 2. 6...10 times more synaptic vesicles were stained by zio in the inhibitory terminals than in the excitatory ones. 3. zio positivity ...	1979	92863
[relations between oxoglutarate transport function and variations of space in rat heart mitochondria (proceedings)].		1979	92958
histochemical reactions of gastrointestinal mucosubstances with high iron diamine after prior oxidation and methylation of tissue sections.	high iron diamine reactions after the prior methylation and oxidation of tissue sections with performic acid or potassium permanganate (metox-hid or ox-met-hid) in epithelial mucosubstances and in mucosal mast cells were studied in tissue samples from the human gastrointestinal tract and were compared with reactions with high iron diamine without any pretreatment (hid) and high iron diamine with the prior methylation (met-hid). high iron diamine reactions after the prior oxidation (met-ox-hid, o ...	1979	93103
analysis of vibrio parahaemolyticus soluble antigens by employing passive hemagglutination.	the passive hemagglutination assay was explored as a sensitive test of immunological reactivity of endotoxin and other antigens prepared from selected strains of vibrio parahaemolyticus. the tannic acid procedure for passive hemagglutination, commonly used with protein antigens, was the only procedure yielding good results with v. parahaemolyticus protein extracts, endotoxins, and related preparations. these results were probably due to the presence of large amounts of protein in the v. parahaem ...	1979	93111
pneumococcal infections and the possible need for a vaccine.	antibiotics and chemotherapeutics have been available for about 40 years, but still bacterial infections constitute some of the greatest problems in medicine. pneumococci causing pneumonia, bacteremia, meningitis and otitis are a leading cause of illness and death. the exact incidence and lethality of pneumococcal infections is not known, however, since they are not reportable diseases in most countries and since microbiological diagnosis is difficult. in the latest years some significant progre ...	1979	93308
relationship of seminal volume to size and disease of the prostate in the beagle.	the seminal volume of young adult beagles was correlated with the size of and disease in their prostates. the ejaculate volume of naturally collected semen increased in a linear manner with prostatic weight in dogs with normal or glandular hyperplastic prostates. this correlation was not observed in the dogs with cystic hyperplasia, in which there was a reduction in volume of 50% in the semen produced for each gram of prostate. there were no significant differences in other seminal characteristi ...	1979	93426
[allergenic properties of the blood serum of drug allergy patients].		1979	93831
study of effectiveness of bleomycin in rat brain tumor model intravenously and intracerebrally.		1979	94056
studies on fibronectin in the skin. iii. indirect immunofluorescence studies in lichen planus.	fibronectin is a glycoprotein which is responsible for a varity of functions in the human organism, such as mediation of contact between cells and between cells and fibres, opsonic qualities, interaction in the stabilization of fibrin, etc. fibronectin is an important constituent of the ground substance having a special affinity to collagen. in indirect immunofluorescence studies its presence has been abundantly demonstrated in normal human skin, in collagen-rich structures such as the basement ...	1979	94206
chlamydia psittaci: growth characteristics and enumeration of serotypes 1 and 2 in cultured cells.	the growth characteristics of chlamydia psittaci serotypes 1 and 2 (ovine and bovine origin) were studed in mouse l cells. formation of inclusions and yield of infectious progeny for serotype 1 were maximal when host cells were treated with cycloheximide and the ph in the cell culture medium was 7.2-7.4. the number of cells that contained inclusions and the infectivity yield for serotype 2 were maximal when the ph was 6.6-7.0. treatments with diethylaminoethyl dextran and cycloheximide increased ...	1979	94339
experimental transmission of wuchereria bancrofti to monkeys.	infective larvae of wuchereria bancrofti from laboratory-raised culex pipiens fatigans and aedes togoi mosquitoes fed on human volunteers in jakarta, indonesia (j strain) and kinmen island, china (k strain) were introduced into taiwan monkeys (macaca cyclopis) by subcutaneous inoculation, by foot puncture, or by permitting infected mosquitoes to feed weekly on the monkeys. some animals were splenectomized and others were treated with varying regimens of immunosuppressants. necropsy was done on m ...	1979	107818
mechanism of folate transport in lactobacillus casei: evidence for a component shared with the thiamine and biotin transport systems.	lactobacillus casei cells have been shown previously to utilize two separate binding proteins for the transport of folate and thiamine. folate transport, however, was found to be strongly inhibited by thiamine in spite of the fact that the folate-binding protein has no measurable affinity for thiamine. this inhibition, which did not fluctuate with intracellular adenosine triphosphate levels, occurred only in cells containing functional transport systems for both vitamins and was noncompetitive w ...	1979	108244
demonstration and characterization of specific binding sites for factor viii/von willebrand factor on human platelets.	the presence of specific factor viii/von willebrand factor (fviii/vwf) binding sites on human platelets has been demonstrated by using 125i-fviii/vwf and washed human platelets. binding is ristocetin-dependent and increases in proportion to the concentration of ristocetin from 0.2 to 1 mg/ml. binding of 125i-fviii/vwf to platelets can be competitively inhibited by unlabeled human or bovine fviii/vwf, but not by human thrombin, fibrinogen, alpha 2-macroglobulin, equine collagen, or a lectin of ri ...	1979	108291
microscopic changes in rat tongue following experimental cryosurgery.	histological changes were studied in the rat tongue for varying periods of time up to 14 days following the application of a cryoprobe to the dorsal surface of rat tongue. within minutes of the application, focal subepithelial vesiculation and hyperemia occurred. at 3 h there was evidence of damage to capillary walls, resulting in hemorrhage. arterioles and venules were thrombosed and there were degenerative changes in the muscle layer of their walls. at 6 h ventral epithelium showed evidence of ...	1979	108379
probenecid-induced increase of 5-hydroxytryptamine synthesis in rat brain, as measured by formation of 5-hydroxytryptophan.	probenecid blocks the efflux of 5-hydroxyindole acetic acid (5-hiaa) from the central nervous system, and has therefore been used for turnover measurements of central 5-hydroxytryptamine (5-ht). this substance also elevates tryptophan (tp) levels in rat brain. in this investigation, the time courses of probenecid and tp levels in rat serum and brain after administration of probenecid were studied. maximal levels of probenecid were reached within 15 min, followed by 50% decrease of serum tp and a ...	1979	108699
feeding parameters with two food textures after chlordiazepoxide administration, alone or in combination with d-amphetamine or fenfluramine.	chlordiazepoxide (5.0, 10.0 mg/kg) reduced the rate of eating and extended the duration of feeding in a 10 min feeding test. it also reduced the latency to feed. both fenfluramine (1.0 mg/kg) and d-amphetamine (0.25 mg/kg) acted to reduce food intake, but by differing mechanisms. fenfluramine reduced eating rate without affecting eating duration, whilst d-amphetamine reduced eating duration without reducing eating rate. the effects of chlordiazepoxide on feeding parameters were generally additiv ...	1979	111292
[oculomotor reflex evoked by vibrassae stimulation in the cat].	the oculomotor effects of vibrissae stimulation have been studied in the "encéphale isolé" non-anaesthetized cat. intracellular recording of lateral rectus motoneurones showed an excitatory projection via the ipsilateral infraorbital nerve to these motoneurones. the afferent fibers are type a alpha, recuited with a low threshold (0.2-0.5 ma) and convey information about vibrissae displacement.	1979	120789
isolation and characterization of actin and myosin from b-lymphocytic guinea pig leukemia cells.	actin and myosin have been isolated from a guinea pig b cell leukemia line, l2c. the m.w. and amino acid compositions of these proteins are similar to actin and myosin from other nonmuscle cell types. l2c actin polymerizes to form filaments and activates the atpase activity of skeletal muscle myosin. actin in crude lymphocyte extracts does not polymerize as well as predicted from the critical concentration of purified lymphocyte actin suggesting that other factors in lymphocyte extracts regulate ...	1979	156229
circular dichroism and ultraviolet absorbance of calf thymus dna in presence of ch3hgoh.		1979	156470
[specific antibodies in the nasal secretum of children with rs viral affection of lower respiratory pathways (author's transl)].		1979	161514
allometric radial growth in muscle, comparing fibres with strong and with weak adenosine triphosphatase activity.	a large flock of male and female white turkeys (meleagris gallopavo) was reared for 22 weeks after hatching. at two weeks intervals small groups of birds were removed from the flock and killed. samples of sartorius muscles were taken from the bird nearest the mean weight for its group. transverse frozen sections were tested for atpase activity by calcium method at ph 9.4. fibres were separated into two categories (strong-atpase and weak-atpase) and their mean minimum diameters were measured with ...	1979	161561
the spontaneous rate of tumours in the laboratory rat: strain chbb: thom (spf).	the aim of this investigation was to examine the time relationship of the rate of development of spontaneous tumours in the rat, strain chbb: thom (spf). the rats were divided into 6 groups, each of which consisted of 100 male and 100 female animals. the first group was killed at the age of 15 months, and the last group when aged 2 1/2 years. thus the time interval between sacrificing the individual groups was 3 months. spontaneous tumours seldom appear in animals up to 15 months of age except i ...	1979	161861
the fate of transplanted pancreatic islets in the rat.	syngeneic pancreatic islets transplanted into the liver or the spleen reverse streptozotocin-induced diabetes in the rat, but allogeneic islets function only briefly and are rejected. shortly after transplantation, thrombi often form around transplanted tissue, particularly around nonislet tissue that contaminates islet preparations. these thrombi are a source of transient liver injury in recipients of intrahepatic grafts. a few days after transplantation, syngeneic islets injected into the port ...	1979	104625
implications for adult roles from differential styles of mother-infant bonding: an ethological study.	ethological observations of maternal and infant behaviors of nine vervet monkey pairs (cercopithecus aethiops sabaeus) showed the effects of differential styles of early maternal responsiveness on later infant competence. those infants receiving the least amount of maternal responsiveness and the most time-off the mother in the first 3 months of development were more socially competent at 6 months of age. the results are discussed within current ethological "attachment" theories. the detachment ...	1979	105083
polychlorinated biphenyl-induced morphologic changes in the gastric mucosa of the rhesus monkey.	the early morphologic events in polychlorinated biphenyl-induced lesions of the gastric mucosa of immature male rhesus monkeys (macaca mulatta) were studied in serial biopsies taken during consumption of diets containing 3, 10, 30, and 100 mg. per kg. (p.p.m.) of aroclor 1242. the severity of the lesions correlated directly with both the duration and the level of exposure. the first changes were seen after ingestion of 30 and 100 mg. per kg. for 2 weeks; changes were not seen until 10 weeks at 3 ...	1979	106183
[isolation and general characteristics of a group of pseudomonas aeruginosa temperate phages].	eighteen temperate phages were isolated from 38 natural strains of pseudomonas aeruginosa. the phages belong to five heteroimmune groups according to the ability of lysogenic variants of the strains pao1 and pat2 to exclude the growth of the superinfecting phage. phages of the ii and v immunity groups are serologically similar; the remaining phages are not inactivated by antisera against phages b26 (ii group) and k1338 (v group). prophages of the ii, iv, and v groups are induced by uv for vegeta ...	1979	106221
[xerophytic microorganisms multiplying under conditions close to martian ones].	the xerophytic cultures bacillus megaterium and mycococcus ruber can grow in the imitated martian conditions. therefore, they are resistant to the extreme factors of the environment: the composition of atmosphere, low pressure, the maximum hygroscopicity of a substrate, periodic freezing-thawing.	1979	106224
[present concepts of ultrastructure of gonococcus].		1979	106576
fat-induced jejunal inhibition of gastric acid secretion and release of pancreatic glucagon, enteroglucagon, gastric inhibitory polypeptide, and vasoactive intestinal polypeptide in man.	the effect of intrajejunal (i.j.) infusion of fat on meal-stimulated gastric acid secretion and release of pancreatic glucagon (pg), enteroglucagon (eg), gastric inhibitory polypeptide (gip), and vasoactive intestinal polypeptide (vip) was studied in seven healthy volunteers. i.j. fat markedly inhibited meal-stimulated acid secretion as compared to a control study with i.j. saline infusion. the acid inhibition was accompanied by augmental plasma concentrations of eg, gip, and vip but not of pg, ...	1979	107575
helical structure of the human umbilical cord.	the helical structure of the human umbilical cord has been studied on 528 full-term cords from normal deliveries, 18 cords from aborted and developmentally normal fetuses with a cr length of 1.2-19.5 cm, 10 cords from monozygotic twins. in order to resolve the discrepancy in the nomenclature of the twist direction, a method has been suggested which takes into account the direction to which the fetus must have rotated to produce the twist. the incidence of the right helical pattern was 64.58%, of ...	1979	419931
lesions of the myofibril in myopathic and normal tissue from seven striated muscles. experimental myopathy of isometric activity produced by phencyclidine and restraint.		1979	419941
stability of estrogen receptors in frozen human breast tumor tissue.	the effect of freezing on the stability of the estrogen receptors in human breast tumors was measured. portions of three tumors kept frozen for 3 days after removal from the patients were analyzed by the sucrose density gradient method. the initial measurements demonstrated positive receptor values. the remaining portions were kept frozen for 30 days, and the receptor values were reevaluated. the 8s receptor was 80% destroyed under these freezing conditions. the 4s receptor was found to be more ...	1979	427754
contribution of adrenal medulla, spleen and lymph, to the plasma levels of dopamine beta-hydroxylase and catecholamines induced by hemorrhagic hypotension in dogs.		1979	438992
the effect of some anti-rheumatic agents on tuberculin pleurisy in the guinea-pig [proceedings].		1979	497564
2,3,7,8-tetrachlorodibenzo-p-dioxin: covalent binding of reactive metabolic intermediates principally to protein in vitro.	2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) is metabolized by the mouse liver cytochrome p-450-mediated monooxygenase system to reactive intermediates which bind 'covalently' to cellular macromolecules. although very difficult to quantitate, the presumably covalent binding to microsomal protein occurs between 120 and 2,640 times more readily than binding to deproteinized dna in the in vitro reaction. because of the extremely high rate of binding to protein rather than to dna, it is visualized tha ...	1979	515166
[response of certain laboratory animals to being fed an ocean fish, the ruvette].		1979	516605
[dry adapting additive and its use in dairy products for approximating the composition of human milk].	the paper concerns a procedure for a new product, dry adapting additive (daa), designed for manufacture of liquid substitutes of breast milk under industrial conditions. the chemical composition of adapted milk mixtures is compared to that of breast milk. procedures for adapted mixtures to be manufactured at city milk kitchens, food concentrate factories and under domestic conditions have been developed, with the mixtures being widely tried on clinical basis.	1979	516610
[ontogenesis of the entorhinal region of the human cerebral cortex].	the ontogenesis of the entorhinal region of the human brain was studied on a series of continuous frontal sections of the brain in 13 pre- and postnatal ages. the sections were stained with crezyl violet. use was made of the quantitative methods. the study revealed some peculiarities in the ontogenetic development of certain subregions and areas of the entorhinal cortex of the human brain. peculiar of the development of the human antorhinal region in the second half of pregnancy is appearance of ...	1979	525118
the effects of sudden airway hypercapnia on the initiation of exercise hyperpnoea in man.	1. in three healthy individuals, the first breath of cycle ergometer exercise was characterized by increases of minute ventilation (ve) and pulmonary capillary co2 output (vco2), with little change of end-tidal pco2, suggesting a concomitant increase of pulmonary blood flow (q) and preservation of v/q status. functional residual capacity fell, depleting lung gas stores of o2 and co2. 2. the following hypothesis purporting to account for the initiation of exercise hyperpnoea was examined (filley, ...	1979	529086
time-course of changes in baroreflex sensitivity during the development of renovascular hypertension in rats [proceedings].		1979	529094
effects of acetaminophen on normal human peripheral blood lymphocytes: enhancement of mitogen- and antigen-stimulated incorporation of tritiated thymidine.	this report describes hitherto unrecognized immunoenhancing properties of acetaminophen on cultured human lymphocytes. the addition of acetaminophen (2.5--300 micrograms/ml) significantly enhanced mitogen-induced blastogenesis. the stimulation of cells by candida albicans, from individuals who were skin-test positive for antigen and two-way responses of mixed lymphocytes, were similarly augmented. cells stimulated in the presence of acetaminophen were comparably enhanced in cultures lasting for ...	1979	535186
an evaluation of the bovine -- onchocerca gibsoni, onchocerca gutturosa model as a tertiary screen for drugs against onchocerca volvulus in man.	in this trial suramin, diethylcarbamazine, trichlorphon, levamisole, mebendazole, melarsonyl potassiu, hoechst 33258 and tinidazole were administered to cattle infected with o. gibsoni and o. gutturosa to determine the usefulness of this screen in predicting the effect of drugs in man against. o. volvulus except for melarsonyl potassium which was macrofilarticidal against o. gutturosa but not o. gibsoni when cattle were slaughtered 6 weeks after treatment. it was concluded that cattle infected w ...	1979	538819
identification of a new allele of es-i segregating in an inbred strain of mice.	a new allele of es-1, designated es-1e, has been identified in the mouse. this allele was discovered segregating among the progeny of a strain dba/2j male and is apparently the result of a spontaneous mutation within this strain. genetic analyses have shown that this mutation is heritable and, further, that both heterozygous and homozygous progeny are viable and fertile. to date, no discernible deleterious effects have been identified as associated with this mutation.	1979	540008
identification of a new allele of es-i segregating in an inbred strain of mice.	a new allele of es-1, designated es-1e, has been identified in the mouse. this allele was discovered segregating among the progeny of a strain dba/2j male and is apparently the result of a spontaneous mutation within this strain. genetic analyses have shown that this mutation is heritable and, further, that both heterozygous and homozygous progeny are viable and fertile. to date, no discernible deleterious effects have been identified as associated with this mutation.	1979	540008
effect of sodium hydroxide upon protein binding to filter paper disks and its significance in the determination of protein in colorimetric and radioisotopic assays.		1979	543545
biochemical properties and drug sensitivity of klebsiella species isolated in lusaka.		1979	544262
effect of dietary fats and triiodothyronine administration on the lipid components of serum and tissues in the rat.	twelve groups of rats were included in this study. six groups (3 males and 3 females) received high fat diets containing 20% of either peanut oil, maize oil or lard. the other six groups received the same diets plus triiodothyronine. triiodothyronine t3 added to diets containing peanut oil caused slight increase in total serum lipids in female rats, while in male rats serum total lipids were increased about 20-fold. t3 administration caused almost no change in aortic total and all lipid fraction ...	1979	549273
abrupt (sharp cut) type sensorineural hearing loss--a human temporal bone study--.	histopathology of a case of bilateral sensorineural hearing loss of abrupt (sharp cut) type is reported. while there was a 45 db gap in threshold between 1,000 hz and 2,000 hz bilaterally, the patient had a good hearing at 1,000 hz and lower frequencies. the patient was suffering from takayasu's arteritis. major histopathological findings were as follows: almost complete loss of the outer hair cells from the basal end to 12 mm area in the left cochlea (length: 30.5 mm) and 13 mm in the right (le ...	1979	549560
bcg at the cross roads.		1979	263227
human cell membrane components dominant in t cell lineage: identification and characterization of human tl-like antigens.	cell membrane components that contain beta 2-microglobulin were purified from cells of a human t cell-type leukemia cell line, hpb-all. they contained membrane components that have the same molecular size and the same subunit structure as hla(a,b,c) antigens but are separable from the typical beta 2-microglobulin-containing cell membrane components, i.e., the hla (a,b,c) antigens, by xenoantibody reagents. a sensitive radioimmunoassay was constructed for detection of the t cell membrane componen ...	1979	387877
scanning electron microscope observations of microvascular anastomosis in the rat carotid artery.	microvascular anastomosis is gaining increasing significance in the field of replantation and reconstructive surgery. although traumatic interference is minimized by microsurgery, thrombotic occlusions remain the major reason for clinical failure. with the improvement of suturing technique studies were directed towards the causes of failure using light and scanning electron microscopy. our study was focussed on the latter aspect. the left common carotid artery of 55 albino rats was transsected ...	1979	387900
human plasma angiotensinogen: a review of purification procedures.	the current status of the purification and characterization of human angiotensinogen is reviewed. one problem encountered in the past has been the copurification of a protein with similar porperties. this protein has tentatively been designated alanine-protein. an efficient separation of angiotensinogen and alanine-protein was obtained on a zinc chelate column. alanine-protein has been purified and its amino acid and carbohydrate composition determined. the cooh-terminal amino acid and the nh2-t ...	1979	390363
[measurements of the temperature during the use of dental ultrasonic devices].	this investigation worked at temperature measurements in cylindric pieces of copper for determination of surface temperatures and in root dentin of calves using ultrasonics by varying intensity, water flowing and pressure. in each experiment two different dental ultrasonic devices were used with two tips. the experiments with sufficient water flowing showed that the spray temperature which was determined separately in further experiments influenced the measurements mainly. on the other hand an i ...	1978	271584
apparatus for uniaxial testing of soft human tissues in vitro.		1978	309051
on the regional and specific serotonin uptake inhibition by lm 5008.		1978	310012
birthday of a sacred cow.		1978	351578
gel filtration of sialoglycoproteins.	the role of sialic acid in the gel-filtration behaviour of sialoglycoproteins was investigated by using the separated isoenzymes of purified human liver alpha-l-fucosidase and several other well-known sialic acid-containing glycoproteins (fetuin, alpha1-acid glycoprotein, thyroglobulin and bovine submaxillary mucin). for each glycoprotein studied, gel filtration of its desialylated derivative gave an apparent molecular weights much less than that expected just from removal of sialic acid. for th ...	1978	356853
connective tissue composition of aortas from non-human primates. a comparative study.	connective tissue composition of aortas from several non-human primate species has been studied in an effort to relate collagen, elastin, ang glycosaminoglycan (gag) content to species susceptibility to atherosclerosis. among the species studied the baboon contained the highest content of gag in the aorta. while the distribution of individual gag varied from species to species, heparan sulfate (hs) was the highest gag in aortas from most of the species. the ratio of hs to chondroitin sulfates (c ...	1978	415748
prostaglandin (pg) analysis in urine of humans and rats by different radioimmunoassays: effect on pg-excretion by pg-synthetase inhibitors, laparotomy and furosemide.	the radioimmunological (ria) determination of prostaglandin (pg) e2 and of pgf2alpha in urine of humans and rats is described in detail. after extraction and chromatography pge2 was determined by using a pge specific antibody or by using either pgb or pgf2alpha specific antibodies after the respective conversion procedures. the three different ria procedures were compared to each other. pgf2alpha was determined by a specific antibody to pgf2alpha. basal excretion of pge2 and of pgf2alpha in heal ...	1978	416466
comparison of interferon action in interferon resistant and sensitive l1210 cells.	translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ...	1978	212514
a three month inhalation toxicity study in the squirrel monkey (saimiri sciureus) with terbutaline sulfate (bricanyl).	a study of the subacute toxicity of inhaled terbutaline sulfate was performed in the squirrel monkey (saimiri sciureus). 3 groups of monkeys were exposed 1 h daily 7 days/week for 3 months to terbutaline sulfate aerosols at concentrations of 0.039, 0.185 and 0.799 mg terbutaline/litre of air respectively. a fourth group was a chamber control receiving air only. the following clinical parameters were evaluated: physical appearance and behavior, weight gain, ophthalmoscopic appearance, electrocard ...	1978	107616
[determinaton of intracellular immunoglobulins by means of immunofluorescence. 1. the standardization of monospecific luminescent antisera against human g-, a- and m-class immunoglobulins in bone marrow preparations from patients with paraproteinemic hemoblastosis].	to assess the specificity and the activity of fluorescent antisera against human g-, a-, m-classes the authors used in the capacity of a substrate, containing specific antigen preparations, bone marrow cells of patients with paraproteinemic hemoblastosis. the method of making the preparations used permitted sufficiently objective assessment of the activity and specificity of the mentioned monospecific fluorescent conjugates. as revealed, the bone marrow preparations could be stored at -70 degree ...	1978	106607
radical scavenging as the mechanism for stimulation of prostaglandin cyclooxygenase and depression of inflammation by lipoic acid and sodium iodide.	certain radical-trapping reducing agents have been shown to stimulate prostaglandin biosynthesis in vitro (1--6) and to depress phorbol myristate acetate-induced mouse ear edema (16). the increased prostaglandin synthesis resulted from influences on the cyclooxygenase. to ascertain whether these alterations were due to direct interaction with the enzyme or to indirect scavenging of the oxidant released during pgg2 reduction, we report the effects of lipoic acid and sodium iodide. both of these a ...	1978	107544
the metabolism and disposition of 3,4,4'-trichlorocarbanilide in the intact and bile duct-cannulated adult and in the newborn rhesus monkey (m. mulatta).		1978	106490
[biochemistry of myocardium taken at autopsy. preliminary report].	the findings after biochemical analysis of heart muscle taken at autopsy are given in this preliminary communication. human myosin is made up of two heavy sub-units and two light sub-units: it is similar to cardiac myosin found in other mammals, but is different in certain characteristics, particularly immunological ones. tropomyosin is made up of two different sub-units. the normal human heart contains 1 mg of collagen and 130 microgram of desoxyribonucleic acid (dna) per 100 mg of fresh tissue ...	1978	152617
[retrograde axonal transport of horseradish peroxidase along the striato-thalamic pathways of cats].		1978	98719
changes in composition of tears of malnourished children.		1978	98738
cats as definitive hosts for sarcocystis of sheep.		1978	98741
studies on the occurrence of peptococcus indolicus and corynebacterium pyogenes in abscesses in swine, and on the occurrence of pc. indolicus in apparently normal skin and mucous membranes of piglets.	pc. indolicus was isolated from 42.7% and cb. pyogenes from 48.7% of 150 pus-samples from abscesses in pigs (slaughter-house material, table i). in 41 specimens the two organisms were found together. further, pc. indolicus was demonstrated in 22.4% of 290 swabs from apparently normal skin and mucous membranes of piglets (autopsy material, table ii). by gel diffusion analysis the strains of pc. indolicus were referred to the serotypes b, c, d, e, or f. the type distribution (table iii) possibly r ...	1978	98755
[immunological relations between mother and child during pregnancy (author's transl)].	the relations between the maternal and foetal organisms during pregnancy are partly very complicated and remain inexplicable. blastocyst, trophoblast, embryo and foetus have membrane antigens at a very early stage, and the immunocompetence of the foetus develops already during the second third of the pregnancy period. many non-specific factors are involved in preventing the castingoff reaction of the foetal organism. the trophoblastic tissue is probably of central importance. the focal point of ...	1978	98927
interferon inducing activity of polyinosinic acid.	although poly(i) is generally considered to be inactive as an interferon inducer, we have found several authentic poly(i) preparations to be effective inducers. their interferon inducing ability varied considerably from one cell system to another. in human diploid fibroblasts, primed with interferon and superinduced by cycloheximide and actinomycin d, all active poly(i) samples proved nearly as effective in inducing interferon as poly(i).poly(c). in primary rabbit kidney cell cultures, the activ ...	1978	99486
salvizol as an intracanal antiseptic for endodontic use.		1978	99707
electrophoretic strand separation of long dnas with poly (u,g) in agarose gels.	we have found that binding of poly(u,g) to single-stranded dna decreases its mobility in 0.3% agarose gels. differential binding to the complementary strands of denatured duplex dna provides a simple method for strand separation. the method is shown to work with bacteriophage lambda dna, adenovirus dna and mtdna for tetrahymena pyriformis. in all cases the strand that binds more poly(u,g) in cscl gradients also binds more in gels. the separated strands can be directly blotted from the gel onto n ...	1978	99728
behavioral measurement measurements of excitability changes in reward sites in the dog: a frequency dependent effect.		1978	99757