Publications

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nitrous acid mutation of transforming dna: consideration of mode of action.apparently nitrous acid produces genetic alterations, expressed as antibiotic-resistant markers, directly on heat-denatured transforming dna of haemophilus influenzae, rather than producing dna which acts as a non-specific mutagen. the markers which arise as a result of treatment with nitrous acid behave similarly to naturally occurring antibiotic markers. in addition, data comparing the expression and replication of induced markers to natural markers suggest that the nitrous acid-induced marker ...196514289610
residual activity of thermally denatured transforming deoxyribonucleic acid from haemophilus influenzae.barnhart, benjamin j. (johns hopkins university school of hygiene and public health, baltimore, md.). residual activity of thermally denatured transforming deoxyribonucleic acid from haemophilus influenzae. j. bacteriol. 89:1271-1279. 1965.-the level of residual transforming activity of heated deoxyribonucleic acid (dna) (i.e., 1 to a few per cent of native dna-transforming activity) was found to be independent of the heating and quenching temperatures and less susceptible than native or renatur ...196514292997
empyema due to hemophilus influenza in infants and children. 196514308119
an aetiological study of respiratory infection in children, edinburgh city hospital, 1961-1963. 196514308350
amelioration by ingestion of phenylalanine of toxic effects of chloramphenicol on bone marrow. 196514222017
[demonstration of "haemophilus influenxae" in sputum]. 196514313202
kinetic studies on the thermal denaturation of deoxyribonucleic acid with a high-frequency heating method. 196514314362
rapid method for demonstrating bile solubility of diplococcus pneumoniae. 196514329473
immunofluorescence techniques for demonstrating bacterial pathogens associated with cerebrospinal meningitis. i. clinical evaluation of conjugates on smears prepared directly from cerebrospinal fluid sediments. 196514331108
hemophilus influenzae psyarthrosis in an adult: a case report. 196514340449
cephaloridine in chronic bronchitis. 196514237936
aminobenzoic acid (paba) in polyethylene glycol-8. 1965315756
[gastro-duodenal complications after coronary surgery (author's transl)]. 1965315751
identification of alpha 1-antitrypsin variants. 1965315710
[a case of quadruple cancer composed of the breast, kidney, liver and uterus carcinomas].a case of quadruple cancer is reported. a 74-year-old female was admitted because of surgery for left breast cancer. abdominal echography showed a mosaic patterned mass of the liver and a solid tumor with central necrosis at the left kidney. echographic diagnosis was hepatoma and grawitz's tumor. all the tumors were justified as being operable. progressive cystorrhagia which was due to radiation cystitis after radiotherapy for uterine carcinoma could not be controlled. autopsy diagnosis was a qu ...19652166900
clinical-pathological conference: case 24, part 1. 1965277639
studies on contact dermatitis in stomatological staff.84 patients with contact dermatitis (38 dentists, 18 dental nurses and 28 dental technicians) were studied. all were patch tested with standard patch test series of the cmea countries and with some professional allergens. 31 (36.9%) of them had allergic occupational contact dermatitis and 39 (46.2%) had irrtiant contact dermatitis. the highest prevalence of irritant contact dermatitis was found among dental surgeons. the percentage of atopics in the group of patients with irritant contact dermat ...19652138093
isolation of two benzocoumarins from 'clover stone' a type of renal calculus found in sheep. 19644158344
the effect of adrenalectomy on the metabolism of the mammary glands of lactating rats. 19644378736
effect of interspecific transformation on linkage relationships of markers in haemophilus influenzae and haemophilus parainfluenzae.nickel, lois (university of pennsylvania, philadelphia), and sol h. goodgal. effect of interspecific transformation on linkage relationships of markers in haemophilus influenzae and haemophilus parainfluenzae. j. bacteriol. 88:1538-1544. 1964.-highly competent cells of haemophilus parainfluenzae were obtained by a modification of the aerobic-"anaerobic" method of goodgal and herriott. the mutant markers for streptomycin and novobiocin resistance in h. parainfluenzae were shown to be unlinked. th ...196414240934
dexamethasone (16-alpha-methyl, 9-alpha-fluoroprednisolone) in obstructive respiratory tract infections in children. a controlled study. 196414243474
mastoiditis in children. 196414222850
[aureomycin in the prevention of recurrent bronchitis and pneumonia; a double-blind study]. 196414224082
fluorescent antibody detection of human occurrence of an unclassified bacterial group causing endocarditis. 196414233141
etiology and mortality of purulent meningitis at the detroit receiving hospital. 196414234268
[a new tetracycline in the treatment of bronchial infection in asthma and chronic bronchopneumopathy]. 196414234367
[conditions favoring bacterial iridescence and observation of the phenomenon]. 196414237170
[the forms of clinical evolution in infection with influenza bacteria]. 196414309222
"black light" inactivation of transforming deoxyribonucleic acid from haemophilus influenzae.cabrera-juárez, emiliano (instituto politecnico nacional, mexico, d.f., mexico). "black light" inactivation of transforming deoxyribonucleic acid from haemophilus influenzae. j. bacteriol. 87:771-778. 1964.-the biological activity (intrinsic genetic markers or nitrous acid mutable regions) of transforming deoxyribonucleic acid (dna) from haemophilus influenzae has been inactivated by "black light" (bl) by two mechanisms: (i) photodynamic action (oxygen-dependent) and (ii) "bl inactivation" (oxyg ...196414139527
the enhancing effect of swine lungworms on swine influenza infections. 196414140870
haemophilus influenzae meningitis--treated with parenteral and intrathecal penbritin. 196414142159
antibiotics in the treatment of maxillary sinusitis. 196414146701
the bacterial flora of sinusitis with an in vitro study of the bacterial resistance to antibiotics. 196414146702
aerobacter aerogenes bacteremia: control of a lethal complication. 196414154552
otitis media in pediatric practice. 196414154585
the kinetics of dna uptake by haemophilus influenzae. 196414188766
[haemophilus influenzae and its importance in clinical practice. ii. pathogenesis]. 196414192999
haemophilus influenzae type-c bronchopneumonia. 196414194995
infectious agents associated with cylindrical bronchiectasis. 196414195402
serological studies on haemophilus influenzae and related species. 6. examination of a selection of previously untypable h. influenzae m- and s-strains for evidence of type specific antigens different from the used type reference standards. 196414197682
serological studies on haemophilus influenzae and related species. 7. examination by means of gel precipitation of somatic antigens prepared by various disintegration procedures in an m- and an r-strain of h. influenzae. 196414197683
serological studies on haemophilus influenzae and related species. 8. examinations of ultrasonically prepared haemophilus antigens by means of immuno-electrophoresis. 196414197684
[bacteriological problems of chronic bronchitis]. 196414200889
[characteristics of the microflora in gastric cancer]. 196414201023
a survey of infections in a community hospital. 196414201577
pathogenicity of haemophilus influenzae. 196414206027
the aetiology of acute middle ear infection. 196414210225
chronic obstructive airway disease. bacterial and cellular content of the sputum. 196414211459
septicemia in infants and children. 196414212462
alterations in the glucose transport mechanism in patients with complications of bacterial meningitis. 196414212464
comparison of lymecycline with tetracycline hydrochloride. 196414214184
ampicillin in the treatment of haemophilus influenzae infections of the respiratory tract. 196414214918
hemophilus influenzae pyarthrosis in an adult. 196414215992
erythromycin in the management of childhood infections. 196414219591
[hemolytic strains of haemophilus]. 196414220007
influence of daily penicillin, tetracycline, erythromycin, and sulphamethoxypyridazine on exacerbations of bronchitis. a report to the research committee of the british tuberculosis association. 196414102014
[therapy of chronic bronchitis]. 196414110967
bacterial species isolated from the sputum of patients with chronic bronchitis. a comparison of homogenization and nonhomogenization techniques. 196414114406
etiology of respiratory infections. further studies during infancy and childhood. 196414115225
[on croup and croup treatment]. 196414118770
the changing pattern of empyema thoracis in pediatrics. 196414118857
bacterial aspects of respiratory infections in young children; diagnosis and therapy. 196414118936
quantitative study of bacteria in mixed populations. a surface-plating method for enumerating, identifying, and determining antimicrobial susceptibility. 196414119126
chronic bronchitis. 196414122804
porcine contagious pleuropneumonia. i. experimental transmission, etiology, and pathology.an acute frequently rapidly fatal respiratory illness occurring as an epidemic disease in argentine swine has been shown to have a bacterium of the genus hemophilus as its causative agent. this organism, for which the name hemophilus pleuropneumoniae is suggested, causes a singular, fulminating pleuropneumonia in experimental swine. the very marked effectiveness of h. pleuropneumoniae as a respiratory pathogen contrasts strikingly with the relatively mild pathogenicity of the well known swine he ...196414129707
porcine contagious pleuropneumonia. ii. studies of the pathogenicity of the etiological agent, hemophilus pleuropneumoniae.hemophilus pleuropneumoniae is highly pathogenic for swine when given intranasally. as few as 100 organisms induce characteristic porcine contagious pleuropneumonia (pcp) and, when as many as one-half million are given, the infection usually proceeds to a fatal termination. while the organism is highly pathogenic when introduced by way of the respiratory tract, it is innocuous when given subcutaneously even in large numbers. swine that have been inoculated subcutaneously are rendered solidly imm ...196414129708
[threat of suffocation in haemophilus influenzae]. 196414131550
combined pyarthrosis, meningitis and septicemia due to hemophilus influenzae, type b. report of case. 196414132439
[diagnosis of whooping cough by the immuno-fluorescence technic]. 196414132902
albamycin-t: an in vitro trial in uganda. 196414133990
bacteriology and antibiotic treatment of acute maxillary sinusitis. 196414135207
[sensitivity to antibiotics of haemophilus influenzae strains]. 196414135859
[medical treatment of purulent meningitis]. 196414137089
[medical treatment of purulent meningitis]. 196414137090
danomycin, a new antibiotic. 196414157008
clinical entity of cryptogenic mycotic aneurysm. 196414159066
the survival of haemophilus influenzae and pneumococci in specimens of sputum sent to the laboratory by post.the isolation rates of h. influenzae and pneumococci from fresh specimens of sputum are compared with those from samples sent to the laboratory by post. the rate for both organisms from postal specimens is found to be approximately one half of that from fresh ones. the finding that postal specimens tend to be more acid than fresh ones does not seem to bear significantly on the survival of organisms. the examination of three fresh specimens from each patient, instead of a single sample, increases ...196414159453
measurement of antibodies reacting with capsular antigens of haemophilus influenzae.a simple haemagglutination procedure is described which measures antibodies that react with capsular antigens of haemophilus influenzae. abnormally high antibody titres of appropriate type-specificity are common in the blood of human subjects who are known to have carried capsulate strains of h. influenzae. it is not yet clear whether all such antibodies are due to such carriage.196414159464
short-term storage of haemophilus influenzae.by a simple procedure, using a readily reproducible medium, most strains of h. influenzae can be stored for four weeks or more and can be sent through the post. capsulate strains can be stored in this way without apparent change.196414159465
penicillinase-resistant penicillins and cephalosporins. 196414160224
the epidemiology of the origin and perpetuation of a new disease. 196414161259
[haemophilus influenzae and its important in clinical practice. i. microbiological-epidemiological aspects]. 196414162969
croup. 196414163227
typing of haemophilus influenzae with fluorescent antibody reagent. 196414166687
antibacterial activity of lincomycin and pristinamycin: a comparison with erythromycin. 196414171066
nonspecific abscess of the lung: 129 cases. ii. bacteriology. 196414171727
hemophilus influenzae pyarthrosis in an adult. 196414172272
cephalothin--a new antibiotic. preliminary clinical and laboratory studies. 196414172279
[the bacterial flora of the sputum in chronic bronchial inflammations. review of the literature and casuistic contribution]. 196414180470
the relationship of results of sputum cultures to clinical effects in a controlled trial of continuous antibiotic treatment of chronic bronchitis with demethylchlortetracycline or penicillin-v. 196414181067
deafness following hemophilus influenzae meningitis. 196414096396
pneumonia in hospital practice in edinburgh 1960-1962. 196414104970
the bacterial flora of the upper respiratory tract and sputum of working men. 196414106344
primary atypical pneumonia: current concepts. 196414106884
crystalline beta-d-ribofuranosyl-beta-d-ribofuranoside: a new diriboside synthesis. 19645294934
[drug therapy of endometriosis]. 19641018834
[electrophysiologic studies of postoperative conduction disturbances following surgical closure of ventricular septal defect (author's transl)]. 1964480747
[the late follow-up results of congenital heart disease in japan (author's transl)]. 1964480746
[lymph node metastases in carcinoma of the lung (author's transl)]. 1964480734
hepatotoxicity in patients with liver disease.the biochemical and physiological disturbances caused by liver disease may enhance the toxicity of drugs. besides alterations in liver blood flow and drug binding, a decreased rate of drug metabolism is an important phenomenon. studies with phenazone, a model drug, demonstrates that the rate of microsomal drug metabolism is related to the degree of metabolic hepatic impairment. individual dosage adjustments in patients with liver disease are complicated for many drugs, because of the counteracti ...1964277091
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