Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| studies on shigella isolated in southern taiwan. | during 1969, a total of 1,476 fecal and rectal swab specimens was collected from children with diarrhea and 249 strains of shigella were isolated. the incidence was 16.9%. the serotypes of 249 strains were: shigella dysenteriae, 1.6% (4 strains); s. flexneri, 73.1% (182 strains); s. boydii, 3.2 (8 strains) and s. sonnei, 22.1% (55 strains). there was no marked difference of the isolation rate throughout the whole year. the susceptibility of shigella isolates to chemotherapeutic agents were also ... | 1976 | 1036983 |
| presence of messenger specifying sequences in the dna of chromatin subunits. | messenger-specifying sequences in subunits of human lymphocyte chromatin were detected by hybridization of dna complementary to cytoplasmic polyadenylylated rna with dna isolated from the subunits. comparison of the kinetics and extents of hybridization of complementary dna with chromatin subunit dna and with nuclear dna showed that most of the repetitive sequences and single copy sequences in mrna are present in chromatin subunits. this result indicates that inclusion of a dna sequence into the ... | 1976 | 1064026 |
| the effector cells in human peripheral blood mediating mitogen-induced cellular cytotoxicity and antibody-dependent cellular cytotoxicity. | the identity of the effector cells in human peripheral blood capable of mediating mitogen-induced cellular cytotoxicity (micc) and antibody-dependent cellular cytotoxicity (adcc) was investigated utilizing effector cell populations consisting of purified polymorphonuclear leukocytes, macrophages, lymphocytes, and cell surface immunoglobulin (sig)-negative and sig-positive lymphocyte subpopulations obtained by sephadex anti-fab immunoabsorbent column fractionation techniques. chicken erythrocytes ... | 1976 | 1087314 |
| diagnostic value of indirect hemagglutination in the seroepidemiology of shigella infections. | to evaluate the usefulness of the indirect hemagglutination (iha) test in the epidemiological investigation of shigellosis, single serum specimens were tested from 50 patients with shigella dysenteriae 1 (shiga bacillus) infections, 103 asymptomatic contacts of these cases, 267 adult and 100 student control, and serum specimens collected during two outbreaks caused by s. sonnei and one outbreak due to s. flexneri 6. in patients with s. dysenteriae 1, 74% demonstrated titers of greater than or eq ... | 1976 | 767361 |
| pathogenesis of shigella diarrhea. serum anticytotoxin antibody response produced by toxigenic and nontoxigenic shigella dysenteriae 1. | the serum antitoxin response to the cytotoxin contained in preparations of shigella dysenteriae 1 (shiga's bacillus) exotoxin was studied in natural and experimental infections of man. natural infection resulted in the rapid appearance of toxin-neutralizing antibody, which disappeared some time between 9 and 18 mo after infection. experimental infection of human volunteers provided the opportunity to study immunoglobulin class of the antibody in sera obtained serially from 7 to 50 days after inf ... | 1976 | 1107354 |
| [diagnostic problems in gout in a 44-year-old man]. | 1976 | 1251615 | |
| radioimmunoassays for free and conjugated trienbolone and for trienbolone acetate in bovine tissue and plasma samples. | a specific, sensitive, precise and accurate radioimmunoassay has been developed for the quantitation of the synthetic anabolic steroid trienbolone acetate (tba) and its major metabolites, free and conjugated trienbolone (tboh) in bovine tissues and plasma. with the extraction procedure described unspecific interference with the antigen-antibody reaction could be ruled out. the assay can significantly detect amounts of more than 40 pg tboh and 70 pg tba. 0.1 - 2.0 g tissue and 0.1 - 1 ml plasma a ... | 1976 | 1273899 |
| [an analysis of meat products as possible factors responsible for transmission of dysenterial toxic infections]. | the paper carries experimental data derived from a bacteriological analysis of infected minced meat products for the presence of shigella sonnei and for ascertaining technological stages non-compliance with whose proper course presents the greatest epidemiological hazards. the procedures employed in analyzing infected meat products are shown to be sufficiently sensitive, for they enable one to count shigella dysenteriae in numbers of 102-106/g, depending upon the degree of total bacterial contam ... | 1975 | 1108439 |
| letter: reactions of cartilage. | 1975 | 1113834 | |
| isolation of cyclic 3',5'-pyrimidine mononucleotides from bacterial culture fluids. | 1975 | 1147989 | |
| dermo--epidermal adhesion and its effect on epidermal structure in the mouse. | evidence is presented that dermo--epidermal adhesion is low in mouse ear. consequently the pressure caused by mitotic activity in the basal epidermal layer is readily relieved by cell extrusion distally and the number of basal cells per unit skin area remains low. the rule then is that the number of distal cells per unit skin area must be equally low, and the epidermis is therefore thin. conversely, dermo--epidermal adhesion is high in mouse sole-of-foot epidermis, and the mitotic pressure leads ... | 1975 | 1201191 |
| [changes in the composition of intracellular lipids and hydrocarbons in candida tropicalis in the absence of growth]. | the fatty acid composition of lipids and the composition of hydrocarbons were studied in candida tropicalis cultivated on a medium with propionic acid and incubated in the conditions of starvation and on a medium containing glucose-1-6-14c but no nitrogen. intracellular fatty acids with an odd number of carbon atoms were found to be easily metabolized by yeast cells. the content and composition of intracellular hydrocarbons were very labile and underwent intensive transformation caused by change ... | 1975 | 1214607 |
| epithelio-mesenchymal interface during mouse kidney tubule induction in vivo. | transmission and scanning electron microscopy were used to study the epithelio-mesenchymal interface between the interacting mouse ureter-bud and the metanephric mesenchyme. the gap between the epithelial and mesenchymal cells varied in width. at the stalk of the ureter-bud the interspace was often about 1 mum, but in the inductively active areas at the tips of the branching ureter-bud epithelio-mesenchymal contacts were seen through discontinuities in the basal lamina. at these points the gap b ... | 1975 | 1240119 |
| [bacteriological and epidemiological considerations on shigelloses in south vietnam (1969-1973)]. | during the period from 1969 to 1973, a rectal swabs from 13.943 diarrhea patients of all ages were examined by bacteriological surveys. from these specimens, 981 strains of shigella were isolated. the most commonly encounted were shigella flexneri 2. all of strains of shigella isolated were highly resistant to aureomycin, tetracyclin, terramycin, novobiocin and chloramphenicol. there has been an increase in the development of multiresistance of shigella. colimycin and streptomycin were the most ... | 1975 | 770024 |
| somatic antigen of shigella dysenteriae type 3. structural features of specific polysaccharide chain. | on mild acid hydrolysis of lipolysaccharide from shigella dysenteriae type 3 the o-specific polysaccharide (hapten) was obtained which appeared to be acidic branched hexosaminoglycan. the repeating unit of this polysaccharide represents a pentasaccharide composed of two d-galactose residues, n-acetyl-d-galactosamine, d-glucose and unidentified acidic component. on the basis of methylation analysis, periodate oxidation, partial acid hydrolysis and chromic anhydride oxidation it is concluded that ... | 1975 | 1089541 |
| antimicrobial resistance of shigellae isolated in michigan. | patterns of antimicrobial resistance were studied for 213 strains of shigellae isolated in rural and urban areas of michigan by quantitative techniques: 66% of these organisms were resistant to ampicillin, tetracycline, cephalexin, or chloramphenicol or had multiple resistance to various combinations of these antibiotics. the incidence of resistant organisms was higher in the detroit-wayne county area, which is the most urban part of the state. nalidixic acid and oxolinic acid were noted to be q ... | 1975 | 1089819 |
| observations on the serologic changes in the recombinants in shigella flexneri serotype 4a. | studies on the antigenic composition of 84 diagnostic strains of s. flexneri serotype 4a and their lac+ recombinants from a cross with e. coli hfrc were carried out. considerable differentiation of agglutination reaction was found both in original material and in recombinants. an interesting group included recombinants which completely lost their capability to agglutinate with sera specific for type and group antigens and preserved only the capability to agglutinate in the polyvalent serum of s. ... | 1975 | 1090112 |
| comparison of secretory and histological effects of shigella and cholera enterotoxins in rabbit jejunum. | the purpose of this study was to compare the actions of shigella toxin and cholera toxin to determine if mucosal damage is a prerequisite for shigella toxin-induced secretion. the secretory response to maximal doses of cholera toxin and shigella toxin were compared. the maximal rate of secretion and the electrolyte and protein concentration of the intestinal fluid were similar for both toxins. on the other hand, the time of onset after exposure to the toxin was 105 min for shigella toxin and 15 ... | 1975 | 1090481 |
| occurrence of the bacteriophage lambda receptor in some enterobacteriaceae. | in escherichia coli k-12, the receptor for phage lambda is an outer membrane protein which inactivates the phage in vitro. lambda receptor activity was found in extracts from all wild strains of e. coli tested, although most of them fail to support growth of the phage. in some cases this failure is due to a masking of the receptor in vivo, the bacteria being unable to adsorb the phage or to react with antireceptor antibodies. in other cases, adsorption does occur, and the nature of the block in ... | 1975 | 1090748 |
| shiga bacillus dysentery associated with marked leukocytosis and erythrocyte fragmentation. | granulocytic leukemoid reactions (white blood cell counts greater than 50,000 with myelocytes and promyelocytes in the peripheral blood) were documented in 15 per cent of 273 patients with dysentery due to shigella dysenteriae, type 1 (shiga bacillus) in bangladesh. peak granulocytosis occurred during the second week of illness, when the children were commonly afebrile and diarrhea had ceased or was subsiding. more than half of the patients with leukemoid reactions subsequently developed a fall ... | 1975 | 1090770 |
| production and characterization of exotoxin(s) of shigella dysenteriae type 1. | a semicontinuous fermenter system was developed in which broth culture filtrates of shigella dysenteriae type 1 yielded substantial amounts of exotoxin. biologic activity of the exotoxin was characterized by means of three assays: the rabbit ileal loop for fluid evocation (enterotoxicity), mouse lethality after parenteral injection (neurotoxicity), and hela cell toxicity in vitro (cytotoxicity). although the culture filtrate was highly active, disc electrophoresis revealed that the toxin is a mi ... | 1975 | 1092769 |
| superiority of macconkey's agar over salmonella-shigella agar for isolation of shigella dysenteriae type 1. | the efficiency of macconkey's agar in the isolation of various types of shigella was compared with that of salmonella-shigella (ss) agar during an extensive 18-month outbreak of disease caused by shigella. in all, 1,580 isolates of shigella were obtained from 12,307 rectal swab and fecal samples of patients with diarrhea and their contacts by direct plating onto macconkey's and ss agars. shigella dysenteriae type 1 and shigella flexneri constituted 55 percent and 33 percent of all isolates, resp ... | 1975 | 1094073 |
| letter: hemolytic uremic syndrome after shigellosis. | 1975 | 1094293 | |
| proceedings: dissociation of bacterial pyrexia from prostaglandin e activity. | 1975 | 1097014 | |
| selective cleavage of glycosidic linkages: studies with the o-specific polysaccharide from shigella dysenteriae type 3. | treatment of the o-specific polysaccharide from shigella dysenteriae type 3 with hydrazine in the presence of hydrazine sulphate resulted in quantitative n-deacetylation with the formation of a modified polysaccharide containing free amino groups. oxidation of the modified polysaccharide with periodate did not destroy the 2-amino-2-deoxygalactose residues, thus indicating that they were substituted at position 3. acid hydrolysis of the modified polysaccharide afforded 3-o-(2-amino-2-deoxy-beta ... | 1975 | 1097111 |
| shigella strains associated with infantile diarrhea in the kaohsiung area. | in 1969 and 1974, 375 shigella strains were isolated in the kaohsiung area, and their serotypes and in vitro susceptibility to antimicorbial agents were studied. in 1969, 249 (16.2%) strains were isolated from 1,476 specimens collected from infantile and young children dirrheal cases, whereas 126 strains (11.6%) were isolated from 1,086 specimens in 1969. the isolation rates were higher in may (21.2%), october (20.8%), april (20.6%), august (19.7), november (18.8%) and january (18.5%), than in o ... | 1975 | 1097211 |
| [antigenic relationships between "levinea amalonatica" and "shigella dysenteriae" and "boydii" (author's transl)]. | twenty-eight strains among thirty-five levinea amalonatica show o antigenic relationships with shigella as follows: with s. dysenteriae 3 (5 strains), s. dysenteriae 4 (1 strain), s. dysenteriae 5 (3 strains), s. dysenteriae 7 (11 strains), s. boydii 6 (7 strains), and with both s. boydii 15 and s. dysenteriae 8 (1 strain). these strains do not induce purulent keratogenous conjunctivitis in guinea pigs as shigella do. | 1975 | 1098541 |
| an outbreak of dysentery caused by shigella dysenteriae type 1 on a coral island in the bay of bengal. | an epidemic of severe dysentery occurred on st. martin island in the bay of bengal at a time when the island, with a population of 1,318, was isolated from the mainland because of the monsoon season. there were 434 cases and 28 deaths within a three-month period. mortality (2%) was limited to the very young and the elderly. shigella dysenteriae type 1 (shiga bacillus) was isolated from 12 of 65 rectal swab specimens. all strains gave similar biochemical reactions and were resistant to tetracycli ... | 1975 | 1099145 |
| epidemiologic investigation of an outbreak of shiga bacillus dysentery in an island population. | an epidemic of dysentery broke out in st. martin island during may through july 1973. the epidemic was caused by shigella dysenteriae type 1. the dysentery could not be controlled by conventional antibiotics and other antidysenteric drugs. the average attack rate was 32.9%. the age specific attack rate was highest in the age group 1-4 years (52.2%). the attack rates were higher in smaller families. the rates were not greatly different amongst people using different sources of water. the overall ... | 1975 | 1101385 |
| some immunochemical and chemical aspects of s and r shigella dysenteriae 1 endotoxins. | endotoxins of s and r forms of shigella dysenteriae 1 were prepared by nacl-na citrate extraction, purified by gel chromatography on sephadex g 200 and on sepharose 4b and subjected to immunochemical and chemical analysis. the toxins contained 25--30% of lipids, 40--50% of carbohydrates and 14--24% of protein. the lipid and protein moieties of the lipopolysaccharide-protein complexes exhibited no significant difference, whereas the sugar moieties differed markedly (both qualitatively and quantit ... | 1975 | 1102598 |
| superinfection immunity and prophage repression in phage p1. ii. mapping of the immunity-difference and ampicillin-resistance loci of p1 and phi amp. | 1975 | 1103441 | |
| selective cleavage of glycosidic linkages: studies with the polysaccharide component of shigella dysenteriae type 6 lipopolysaccharide. | the polysaccharide component obtained from the lipopolysaccharide of shigella dysenteriae type 6 was subjected to milk hydrolysis with acid, and the products were fractionated on sephadex g-50. an acidic hexosaminoglycan and a core oligosaccharide fraction were obtained, the former containing d-glucose, d-galactose, 2-acetamido-2-deoxy-d-galactose (in the ratios 1:1:1), and an unidentified acidic component (x). the hexosaminoglycan was n-deacetylated and then hydrolysed and deaminated to give 3- ... | 1975 | 1104165 |
| [pathogenicity factors of gramnegative enteropathogenic bacteria and pathogenesis of intestinal diseases (author's transl)]. | enterotoxins as produced by the majority of enteropathogenic bacteria play a central role in the pathogenesis of cholera and e. coli enteritis but are obviously of little significance as to the development of salmonella enteritis and dysentery. pathology of salmonella enteritis and dysentery results from multiplication of bacteria within the bowel wall and from the damage of tissue caused thereby. the lipopolysaccharides (endotoxins) of invasive enteropathogenic bacteria do not possess the chara ... | 1975 | 1106437 |
| the destruction of tumor cells by alloimmune peritoneal cells: mechanism of action of activated macrophages in vitro. | 1975 | 804549 | |
| microbial development of drug resistance: mechanisms and clinical significance. | bacteria have demonstrated a disconcerting ability to develop resistance to antimicrobial agents nearly as quickly as new compounds become available. during the past two decades the molecular bases of several types of resistance have been elucidated. mechanisms of resistance include the transference of genetic material either through conjugation (involving direct contact between microorganisms), or indirectly through transduction (involving bacteriophages). in addition to this "infectious" drug ... | 1975 | 806419 |
| conditions critical for optimal visualization of bacteriophage adsorbed to bacterial surfaces by scanning electron microscopy. | the potential of scanning electron microscopy as a tool for the detection of viruses on cell surfaces has been studied using bacteriophage p1 adsorbed to shigella dysenteriae as a model system. viral particles were readily detectable by scanning electron microscopy on the surface of infected cells which were fixed with glutaraldehyde followed by postfixation in oso4 and prepared by critical point drying. the virus-studded surface of the infected cells differed markedly from the relatively smooth ... | 1975 | 806704 |
| the influence of some cations on bacterial endotoxins: copper. | in the course of its isolation and purification, bacterial endotoxin may be contaminated by some inorganic cations. the present study was concerned with cu-2+ contamination of the lipopolysaccharide-protein complex (lps) extracted from shigella dysenteriae 1 s and r strains. the cu-2+ contamination level of lps prepared by raynaud's method and partly purified through sephadex g200 and sepharose 4b was in the range of 1-5 mug cu-2+/mg lps. crude raynauds extract, similarly as lps prepared by west ... | 1975 | 808051 |
| antigenic specificity of cell-mediated antitumor reaction in the msv system. | 1975 | 60997 | |
| particulate cytochrome c in agrobacterium tumefaciens. | in agrobacterium tumefaciens the main part of c-type cytochromes is tightly bound to the bacterial cell envelope structures. several techniques were attempted to solubilize these cytochromes. the highest yield of cytochromes released is obtained by treatment of particle suspensions with 5% triton x-100. further purification confirms that the proteins are not really solubilized, but still aggregated in small heterogeneous complexes. chromatography on a cm-cellulose column demonstrates that at lea ... | 1975 | 58606 |
| [method of preparation and use of paper bands with levomycetin for isolation of shigella]. | 1975 | 48593 | |
| [improvement of the method of isolation of the causative agents of acute intestinal diseases]. | 1975 | 48601 | |
| effects of renal nerves on renal hemodynamics. i. direct stimulation and carotid occlusion. | renal nerves were stimulated either directly (loop electrodes) or indirectly (bilateral carotid occlusion with maintenance of control blood pressure) in anesthetized dogs to determine the effects on renal blood flow (rbf), glomerular filtration rate (gfr), sodium excretion (unav), and intrarenal distribution of blood flow (microsphere method). direct nerve stimulation decreased rbf 20% in 9 of 10 dogs; but gfr, unav, and intrarenal distribution of blood flow did not change significantly. carotid ... | 1975 | 124020 |
| [possible causes determining the developmental rhythm of populations of the nasopharyngeal gadfly of sheep, oestrus ovis l. (diptera, oestridae)]. | on the basis of observations undertaken in azerbaijan and available literary data the author considers the hypotheses concerning the reasons causing the delay of the ist instar larvae development and determining the age structure changes in population of oestrus ovis l. within a year. the main reasons are as follows: factors depending on the population density at the larval phase, the light day duration within the life cycle of the botfly females. | 1975 | 124845 |
| behavioral changes following vmh lesions in rats with controlled insulin levels. | the effects of ventromedial hypothalamic (vmh) lesions were studied in female rats made diabetic with streptozotocin that were given twice daily injections of protamine zinc insulin (0.75 mu/100g/day) and in non-diabetic animals of the same sex. hyperphagia resulted from vmh lesions in both diabetic animals whose insulin levels were controlled and in non-diabetic animals. all animals with lesions exhibited persistent increases in feeding during the light protion of the light-dark cycle. signific ... | 1975 | 125424 |
| effect of methysergide, a blocker of serotonin receptors, on plasma prolactin levels in lactating and ovariectomized rats. | the effect of methysergide (mes, 2.5 mg/100 g body wt), a serotonin antagonist, on prolactin release has been studied in lactating and ovariectomized rats. mes caused significant increases in prolactin release in both animals. studies in ovariectomized, hypophysectomized rats indicate that this effect is not due to a decrease in the peripheral metabolism of prolactin. in vitro incubations of anterior pituitary fragments with mes failed to demonstrate any increase in prolactin release, suggesting ... | 1975 | 126860 |
| characterization of 5.8s ribosomal ribonucleic acid in neurospora crassa. | neurospora crassa ribosomes contain a species of ribonucleic acid (rna) of molecular weight 54,000, similar to 5.8s ribosomal rna previously described for other eukaryotic organisms. the 5.8s rna from n. crassa was found to be released by heat treatment at 60 c from 25s ribosomal rna but not from 18s ribosomal rna. the base composition of n. crassa 5.8s rna was similar to that of 5.8s rna from saccharomyces cerevisiae, but differed from animal 5.8s rna. during the course of this study, it was di ... | 1975 | 126993 |
| the hurler syndrome: treatment of cultured hurler fibroblasts with normal human serum. | prolonged replacement of fetal calf serum by normal human serum for the enrichment of medium during tissue culture of hurler fibroblasts resulted in increased acid mucopolysaccharides in the cells and in the medium. the predominant intracellular mucopolysaccharide had the characteristics of dermatan sulfate when hurler cells were treated with either serum. normal human serum contains a nonspecific coreective factor capable of augmenting the loss of 35so4-amps from hurler cells, but not from norm ... | 1975 | 127180 |
| [first izolation of enterobacterium a 12 (sachs) in bratislava in the year 1971 (author's transl)]. | 1975 | 127664 | |
| scattered mitoses in mature joint cartilage in rabbits after local trauma. a chalone effect? | this is a demonstration of local traumatization of articular cartilage inducing mitoses in parts of a joint other than the site of inquiry. parts of one of the patellar cartilages of the full-grown rabbit were scored while the other knee was subjected only to arthrotomy. radioactive thymidine and autoradiographic technique demonstrated that labeled chondrocytes appeared not only around the score in the patella but also scattered in the tibia and femoral condyles. whether the mechanism of regiona ... | 1975 | 127681 |
| immunologic relationship among fibrinolysins secreted by cultured mammalian tumor cells. | 1975 | 127717 | |
| identification and actions of gastric inhibitory polypeptide. | 1975 | 128084 | |
| in vitro fertilisation of human oöcytes. | this paper describes attempts to cure infertility due to irremediable fallopian tube lesions by the laparoscopic recovery of pre-ovulatory ovarian oöcytes, their fertilisation in vitro, and their subsequent reimplantation into the uterine cavity. | 1975 | 128140 |
| [changes in the lungs and the mass of the right ventricle of the heart in chronic hypoxia (experimental-morphological study)]. | in experiments on 105 white rats using histological, histochemical, and morphometric methods the state of the lungs following daily "rises" in a pressure chamber to the "hight" of 5000--9000 m at verious time intervals--from 1 day to 9 weeks was studied. in 18 animals "ascents" were preceded by sinistral pulmonectomy. in parallel, the heart was investigated by the method of separate weighing. at initial stages changes in the lungs were characterized predominantly by impairment of the blood- and ... | 1975 | 128341 |
| the effect of butacaine on adenine nucleotide binding and translocation in rat liver mitochondria. | the effect of the local anaesthetic, butacaine, on adenine nucleotide binding and translocation in rat liver mitochondria partially depleted of their adenine nucleotide content was investigated. the range of butacaine concentrations that inhibit adenine nucleotide translocation and the extent of the inhibition are similar to the values obtained for native mitochondria. butacaine does not alter either the total number of atractyloside-sensitive binding sites of depleted mitochondria, or the affin ... | 1975 | 128352 |
| [organization of the veterinary service of a dairy complex]. | 1975 | 129913 | |
| regulation of mitochondrial protein turnover by thyroid hormone(s). | 1. the effect of thyroidectomy on turnover rates of liver, kidney and brain mitochondrial proteins was examined. 2. in the euthyroid state, liver and kidney mitochondria show a synchronous turnover with all protein components showing more or less identical half-lives compared with the whole mitochondria. the brain mitochondrial proteins show asynchronous turnover, the soluble proteins having shorter half-lives. 3. mitochondrial dna (m-dna) of liver and kidney has half-lives comparable with that ... | 1975 | 177002 |
| degenerative alterations in the ventral cochlear nucleus of the guinea pig after impulse noise exposure. a preliminary light and electron microscopic study. | guinea pigs were exposed to the noise of 40 shots of an alarm pistol held at a distance of about 60 cm. the ventral cochlear nuclei were studied in phase contrast and electron microscopy after both survival periods and longer periods of up to 55 days survival. marked degeneration of primary cochlear nerve endings and of synapting secondary neurons of the posterior caudal part of the ventral cochlear nucleus (avcn) and the octupus cell area (oca) of the posterior ventral cochlear nucleus (pvcn) w ... | 1975 | 175774 |
| a radiometric method for predicting effectiveness of chemotherapeutic agents in murine leprosy. | a simple radiometric method has been developed for evaluating the effect of drugs on the metabolism of m. lepraemurium. the method is based on the measurement of the 14co2 produced through bacterial metabolism of acetate-u-14c. seventeen drugs were tested: bacitracin, cephaloridine, chloramphenicol, cycloserine, dactinomycin, dds, ethionamide, inh, kanamycin, methenamine mandelate, nitrofurantoin, oxacillin, polymyxin b, rifampicin, streptomycin, sulfadimethoxine and vancomycin. the drugs which ... | 1975 | 176120 |
| acid mucopolysaccharides in metal-induced tumor and connective tissue capsules surrounding implants in rats. | 1975 | 142824 | |
| classification of enterotoxins on the basis of activity in cell culture. | two cell culture systems were used in a study of the biological properties of several bacterial enterotoxins in vitro. by means of one model, in which hela cell monolayers were used, cytotoxic effects, interms of detachment of cells from a glass surface due to cell death, were assayed. by means of the second model, activation of the adenyl cyclase-cyclic adenosine 3', 5'-monophosphate (amp) system, in terms of increased steroidogenesis by y-1 adrenal cells (an effect which we have termed cytoton ... | 1975 | 162926 |
| cyclic 3',5'-amp phosphodiesterase of rabbit aorta. | cyclic amp and cyclic gmp phosphodiesterase activities (3' : 5'-cyclic amp 5'-nucleotidohydrolase, ec 3.1.4.17) were demonstrated in the isolated intima, media, and adventitia of rabbit aorta. the activity for cyclic amp hydrolysis in the intima was 2.7-fold higher than that for cyclic gmp hydrolysis. the activity for cyclic amp hydrolysis in the media was approximately equal to that for cyclic gmp hydrolysis, but in the adventitia, cyclic gmp hydrolytic activity was 2.1-fold higher than cyclic ... | 1975 | 164219 |
| cyclic adenosine-3',5'-monophosphate in cerebrospinal fluid during fever and antipyresis. | 1975 | 166164 | |
| template specificity of the cytoplasmic dna polymerase in xenopus laevis oocytes. | 1975 | 167780 | |
| effect of klebsiella pneumoniae enterotoxin on intestinal transport in the rat. | the effects on intestinal transport of either a semipurified preparation of enterotoxin elaborated by klebsiella pneumoniae or similaryly prepared control material were tested by marker perfusion studies in the small intestine of rats. at a concentration of 2 mg/ml, the enterotoxin produced net secretion of water, na, and cl in both jejunal and ileal segments; hco3 transport was not affected. net secretion was evident within 30 min after intorduction of the toxin and was maximal after 90 min. th ... | 1975 | 169297 |
| characterization of monkey peripheral neutrophil granules during infection. | rhesus monkey (macaca mulatta) neutrophils were shown to contain the azurophilic granule maker enzymes myeloperoxidase and beta-glucuronidase but were deficient in the specific granule markers alkaline phosphatase (akp) and lysozyme. isopycnic centrifugation of leukocyte homogenates on linear sucrose gradients resulted in cosedimentation of myeloperoxidase and beta-glucuronidase with an equilibrium density of 1.18. after an intravenous inoculation of monkeys with salmonella typhimurium akp activ ... | 1975 | 170208 |
| solubilization of the [8-lysine]vasopressin receptor and adenylate cyclase from pig kidney plasma membranes. | adenylate cyclase and the [8-lysine]vasopressin receptor were solubilized from pig kidney medulla membranes using the nonionic detergent triton x-100. optimal conditions for solubilization were under continuous stirring in a medium containing 0.5% (/v) triton x-100, 100 mm tris-hcl, ph 8, and 10 mm mgcl2. both adenylate cyclase activity and [3h][8-lysine]vasopressin binding activity were recovered in a -26,000 x g supernatant of detergent-treated membranes. the yield of solubilized adenylate cyc ... | 1975 | 170274 |
| [characteristics and types of clostridium perfringens derived from various animals]. | 1975 | 170433 | |
| effect of shigella enterotoxin on electrolyte transport in rabbit ileum. | shigella dysenteriae i is one of several bacteria which produces an enterotoxin capable of stimulating intestinal water and electrolyte secretion. unlike cholera and escherichia coli enterotoxins which have been shown to increase intracellular cyclic adenosine monophosphate levels in the small intestine, the mechanism by which shigella enterotoxin causes intestinal secretion is not known. to study shigella enterotoxin-stimulated intestinal secretion, rabbit ileal mucosa exposed in vivo to shigel ... | 1975 | 172398 |
| ultrastructural myocardial changes produced by viruses. | some of the ultrastructural pathological alterations in the myocardium produced by viral infections with members of the picornavirus group are described. these alterations varied from mild to severe, with necrosis. in animals infected with coxsackie b1 virus and emc virus, readily identifiable viral crystals were frequently found in association with the myocardial lesions by means of electron microscopy. the electron microscope made it possible to study vary early myocardial changes which were n ... | 1975 | 172990 |
| suppression of pulmonary antibacterial activity following sendai virus infection in mice: dependence on virus dose. | 1975 | 173264 | |
| the pathogenesis of shigella diarrhea. v. relationship of shiga enterotoxin, neurotoxin, and cytotoxin. | the biological activity of the enterotoxin of shigella dysenteriae 1 was compared with that of a well-studied 20-year-old partially purified preparation of neurotoxin from the same organism. enterotoxicity, neurotoxicity, and cytotoxicity were present to an equivalent extent in both preparations. human convalescent antisera and experimental rabbit antisera had equal toxin-neutralizing antibody to the cytotoxic activity in these toxin preparations. multiple protein bands were present in each toxi ... | 1975 | 236346 |
| inhibition of pathogenic enteric bacteria by hyperbaric oxygen: enhanced antibacterial activity in the absence of carbon dioxide. | the antibacterial effects of 24-h exposures to high-pressure oxygen in relation to environmental co(2) were studied at 3 atm absolute (ata) and at 1 ata. eight gram-negative, aerobic and facultatively aerobic, pathogenic enteric bacteria (salmonella typhosa, salmonella paratyphi, salmonella schottmuelleri, shigella dysenteriae, shigella flexneri, proteus vulgaris, pseudomonas aeruginosa, and escherichia coli) were exposed as shallow-broth cultures and agar surface cultures. although broths suppl ... | 1975 | 238466 |
| [antibacterial action by bacteriocin produced by shigella sonnei 100052]. | 1975 | 765567 | |
| [microtubular structures in the cytoplasm of macrophages and their enzymatic activity in interaction with salmonella typhi and shigella dysenteriae]. | 1975 | 765699 | |
| receptors for t2, t4 and t6 phages in sh. dysenteriae 7 and other serotypes of sh. dysenteriae. | the sensitivity of four strains of sh. dysenteriae and of nine strains representing other serotypes of sh. dynsenteriae to phages t2, t4 and t6 was examined. different extracts, prepared from sensitive strains were tested for their capacity of phage inactivation. we found that the receptor substance for phage t2 is localized differently in various strains: in sh. dysenteriae 7, it was found in bacterial extracts obtained by water/phenol at 68 degrees c and in extracts obtained by trichloracetic ... | 1975 | 766504 |
| letter: leukaemoid reaction, haemolytic anaemia, and hyponatraemia in severe shigella dysenteriae type-1 infection. | 1974 | 4133631 | |
| influence of heart rate on regional myocardial blood flow measured with radioactive microspheres in anaesthetized dogs. | 1974 | 4135896 | |
| verification of the previously reported t(3p minus:17q plus) by g banding. | 1974 | 4136169 | |
| editorial: bongo-drum disease. | 1974 | 4136655 | |
| editorial: bongo-drum disease. | 1974 | 4136655 | |
| effects of cyclophosphamide on b- and t-lymphocytes in rheumatoid arthritis. | 1974 | 4136699 | |
| lysogeny and lysosensitivity in shigella dysenteriae group of bacteria. 3. serological specificity of receptors of t2 and t4 phages in shigella dysenteriae 7, strain d7. | 1974 | 4137048 | |
| use of dna-dna annealing to detect new virus-specific dna sequences in chicken embryo fibroblasts after infection by avian sarcoma virus. | labeled, virus-specific dna synthesized in vitro by the virion-associated polymerase of avian sarcoma virus (asv) was used to measure virus-specific sequences in cell dna in three ways: (i) by determining the effect of cell dna upon the reassociation rate of double-stranded polymerase products; (ii) by measuring the kinetics of annealing of single-stranded polymerase product (cdna) to cell dna; or (iii) by measuring the amount of cdna which anneals to a large excess of cell dna. with these three ... | 1974 | 4138674 |
| [immunological relationship between neurotoxin and heavy purified endotoxins extracted from "shigella dysenteriae" (shiga), smooth and rough forms (author's transl)]. | 1974 | 4141595 | |
| [skin test indices with several bacterial allergens in patients with viral hepatitis]. | 1974 | 4141844 | |
| immune responses to myelin basic protein in mycobacterial-induced suppression of experimental allergic encephalomyelitis. | 1974 | 4143110 | |
| letter: ampicillin-resistant shiga bacillus in bangladesh. | 1974 | 4131053 | |
| synthesis of pivaloyloxymethyl 6-n'-cyanoamidinopenicillanates and the antibacterial activity of the corresponding acids. | 1974 | 4148419 | |
| experimental shigellosis and intestinal malabsorption in the mouse. | 1974 | 4151366 | |
| [proceedings: sensitivity of transmitter substances and synaptic formation in cultured neurons]. | 1974 | 4157031 | |
| in vitro antibacterial activity of 2-amino-4(2-ethynyl-1-methyl-5-nitroimidazole)-pyrimidine, a metronidazole derivative with antitrichomonad activity. | 1974 | 4211237 | |
| [transfer of resistance to antibiotics and sulfonamides from shigella dysenteriae 1 (shiga bacillus) to escherichia coli k 12]. | 1974 | 4212868 | |
| genetic and biophysical study of r plasmids conferring sulfonamide resistance in shigella strains isolated in 1952 and 1956. | the conjugative plasmids determining sulfonamide resistance in five shigella strains, each isolated from a different patient, have been characterized. one s. flexneri 2a strain, isolated in 1952, harbored an fi(+) plasmid of molecular weight 53 x 10(6), which specified synthesis of f-like pili and bore determinants for sulfonamide resistance (su) and bacteriocinogeny (col). this plasmid was compatible with plasmids of groups f(i), f(ii), i(alpha), and p. a second s. flexneri 2a strain isolated i ... | 1974 | 4215794 |
| further studies on the role of prostaglandin in fever. | 1. experiments were carried out in unanaesthetized cats to find out if a prostaglandin is the mediator (a) for the long lasting fever which often follows injections of phsyiological salt solutions into the cerebral ventricles or into the cisterna magna, as well as their perfusions through the cerebral ventricles, and (b) for the sodium fever which occurs during a perfusion of the cerebral ventricles with calcium-free artificial c.s.f. a fever mediated by prostaglandin should be accompanied by an ... | 1974 | 4215879 |
| effects of bacterial cardio-stimulating substance on cardiac metabolism in dogs. | 1974 | 4218725 | |
| [bacteriocin production and lysogeny in shigella of subgroup a]. | 1974 | 4219348 | |
| sequential studies of experimentally induced ovine listerial abortion: pathologic changes. | 1974 | 4205017 | |
| amino-terminal sequence of the tryptophan synthetase alpha chain of bacillus subtilis. | the sequence of the 46 nh(2)-terminal residues of the tryptophan synthetase alpha chain of bacillus subtilis was determined and compared with the corresponding sequences of escherichia coli, shigella dysenteriae, salmonella typhimurium, aerobacter aerogenes, serratia marcescens, and pseudomonas putida. a deletion of six residues was found at the nh(2)-terminal end of the alpha chain of b. subtilis. | 1974 | 4206869 |
| depression of polymorph counts by various scrapie agents. | 1974 | 4207411 | |
| proceedings: the effect of parachlorophenylalanine on the response of the conscious cat to intravenous and intraventricular bacterial pyrogen and to intraventricular prostaglandin e1. | 1974 | 4274213 |