Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [urinary magnesium levels in precancerous conditions and various stages of squamous cell carcinoma of the larynx]. | in 100 cases with different stages of planoepithelial laryngeal cancer and in 13 precancerous changes the urine magnesium levels were examined two times by means of absorptive spectrometry before surgery and half a year after. in precancerous period group (i stage according to who) no differences were found in comparison to the control group. as the disease progressed the urine magnesium level deteriorated according to the cancer stages. in iv stage the level was the lowest (p less than 0.01). t ... | 2008 | 2628850 |
| [clinical-experimental examinations on phonetic function in edentulous patients and after insertion of total prostheses measured by the s-sound realization]. | lose of teeth and therapy by prosthesis interfering with the oral sectors that are necessary for s-sound articulation have an important influence on s-sound realization. hitherto, the resulting s-sound changes used to be evaluated only from a subjective point of view. the application of a complex measuring technique for s-sound analysis permitted to determine the influence of the upper and lower jaw plates on s-sound formation by experiments. in another series of experiments, it was shown that e ... | 2008 | 2640388 |
| [statistical and medico-legal investigations on traumatic intracranial injuries (except traffic accidents) on which judicial autopsies conducted]. | judicial autopsies conducted during the period of 24 years and 3 months (jan 1963-mar 1987) at department of legal medicine, kurume university school of medicine have been recorded a total of 1,157 cases including 256 cases caused by the traumatic intracranial injury death. in this report statistical investigations conducted on 112 cases caused by traumatic intracranial injury death with exception of 144 cases caused by traffic accidental death, and the outline of several cases on those are stat ... | 2008 | 2629481 |
| assessment of clinical application of test-dose concept for theophylline in patients with respiratory failure. | the possibility of clinical application of test-dose concept for theophylline was assessed in 11 patients with serious underlying disease who required theophylline. based on the pharmacokinetic parameters calculated from the single intravenous aminophylline administration, they received a continuous infusion of aminophylline in order to maintain about 10 micrograms/ml plasma which is considered to be the lowest therapeutic level. plasma levels during a constant rate infusion were assayed at 6:00 ... | 2008 | 2630628 |
| assessment of clinical application of test-dose concept for theophylline in patients with respiratory failure. | the possibility of clinical application of test-dose concept for theophylline was assessed in 11 patients with serious underlying disease who required theophylline. based on the pharmacokinetic parameters calculated from the single intravenous aminophylline administration, they received a continuous infusion of aminophylline in order to maintain about 10 micrograms/ml plasma which is considered to be the lowest therapeutic level. plasma levels during a constant rate infusion were assayed at 6:00 ... | 2008 | 2630628 |
| the new jersey low-contact-stress knee replacement system: biomechanical rationale and review of the first 123 cemented cases. | a mobile-bearing element, metal-backed, interchangeable knee replacement system has been designed to combine low constraint forces with low contact stresses (lcs), allowing nearly normal joint articulation and loading as well as long-term wear resistance of the implants. the system is versatile, including a large number of component options in variable sizes, and it may be used in both primary and revision arthroplasties. the overall results in the first 123 cemented cases (97 patients) with 2- ... | 2008 | 3753173 |
| the new jersey low-contact-stress knee replacement system: biomechanical rationale and review of the first 123 cemented cases. | a mobile-bearing element, metal-backed, interchangeable knee replacement system has been designed to combine low constraint forces with low contact stresses (lcs), allowing nearly normal joint articulation and loading as well as long-term wear resistance of the implants. the system is versatile, including a large number of component options in variable sizes, and it may be used in both primary and revision arthroplasties. the overall results in the first 123 cemented cases (97 patients) with 2- ... | 2008 | 3753173 |
| [the role of morphologic studies in the diagnosis of malignant neoplasms]. | 2008 | 2603039 | |
| ct of the wrist for the evaluation of traumatic injuries. | computed tomography (ct) of the wrist can help evaluate many types of posttraumatic injuries, particularly bony trauma. most wrist fractures can be diagnosed with routine radiography, but problematic cases and complicated healing fractures can be difficult to evaluate with conventional radiography. ct provides improved contrast resolution and multiplanar imaging. the results of complex healing fractures and fusion procedures can be facilitated with ct. even in the face of advanced osteoporosis c ... | 2008 | 2688677 |
| ct of the wrist for the evaluation of traumatic injuries. | computed tomography (ct) of the wrist can help evaluate many types of posttraumatic injuries, particularly bony trauma. most wrist fractures can be diagnosed with routine radiography, but problematic cases and complicated healing fractures can be difficult to evaluate with conventional radiography. ct provides improved contrast resolution and multiplanar imaging. the results of complex healing fractures and fusion procedures can be facilitated with ct. even in the face of advanced osteoporosis c ... | 2008 | 2688677 |
| the role of transplantation in liver disease. | liver transplantation is rapidly emerging as the most effective treatment pathway for a growing number of acute and chronic liver disease states. indications and contraindications to transplant are undergoing continuous revision and clarification as experience is accrued in the expanding number of treatment centers. for some disorders such as primary biliary cirrhosis, sclerosing cholangitis, and chronic active hepatitis with cirrhosis, the role of transplantation in patient management is obviou ... | 2008 | 2648619 |
| [transplants. reflections on the role of the periodontal ligament and resorption risk]. | 2008 | 2612260 | |
| [transplants. reflections on the role of the periodontal ligament and resorption risk]. | 2008 | 2612260 | |
| takayasu arteritis presenting as retinal and vertebrobasilar ischemia. | a young woman presented with a 4-month history of retinal and vertebrobasilar ischemia. angiography demonstrated narrowing of major branches of the aortic arch. intractable, severe retroorbital pain of the right eye developed after a middle cerebral artery stroke. during 4 weeks of aggressive immunosuppressive therapy including iv high dose bolus corticosteroids and pulse cyclophosphamide, her neurologic deficit improved transiently, but her retroorbital pain persisted. she died of staphylococca ... | 2008 | 2570149 |
| what do you mean? | 2008 | 2583581 | |
| us health care: another canadian sends a message home. | 2008 | 2720532 | |
| [disseminated peritoneal leiomyomatosis. a case report]. | leiomyomatosis peritonealis disseminata (lpd) is a rare benign and mostly asymptomatic disease only occurring in women of reproductive age. because of the disseminated appearance of multiple subperitoneal nodules malignancy is frequently simulated. a report is given on a case of lpd in a 38 year old woman. today the cause of lpd is seen in a specific hormonal stimulation of the pluripotent subperitoneal mesenchyma of the müllerian duct in the minor pelvis. an individual disposition is discussed. ... | 2008 | 2533772 |
| reduction of beta-adrenergic receptors can explain the lack of rebound effect after tertatolol withdrawal. | tertatolol is a potent beta-blocker with no intrinsic sympathomimetic activity (isa) or beta 1/beta 2 receptor subtype selectivity. we provide evidence that tertatolol competitively inhibits beta-adrenergic receptors (beta-ar) and induces a marked and persistent reduction of their number. this has been consistently found in vitro and in vivo. the in vitro study showed that the receptor reduction by tertatolol was rapid (about 1 h at 37 degrees c), slowly reversible and independent of isa. this e ... | 2008 | 2573373 |
| [caudal epidural anesthesia in children]. | 2008 | 4096815 | |
| speech breathing in women. | thirty healthy women representing three age groups (25, 50, and 75 years) were studied with respect to general respiratory function and speech breathing. certain subdivisions of the lung volume differed with age: vital capacity, expiratory reserve volume, and residual volume. speech breathing also differed with age and was characterized by differences in lung volume excursion, rib cage volume excursion, lung volume initiation, rib cage volume initiation, and lung volume expended per syllable. ag ... | 2008 | 2739388 |
| a model for the resistance of the proton channel formed by the proteolipid of atpase. | the conductance observed for single proton channels formed by proteolipids of atpase (schindler and nelson 1982) is rationalized in terms of a hydrogen bonded network model. a simple algebraic expression for the resistance predicted for such a model is presented and the results are compared to the experimental observations. the comparison suggests that the conduction involves a series of bound water molecules and perhaps amino acid side groups. | 2008 | 2580699 |
| neurotransmitters in the brain. | 2008 | 2573362 | |
| outpatient geriatric assessment in a health maintenance organization. its structure, practice, and clinical implications. | the authors review their experience with the implementation of a geriatric assessment unit (gau) within the rhode island group health association, a health maintenance organization (hmo). included is a historical background of the involvement of hmos with care of medicare patients, a description of the structure of an outpatient gau, and the authors' experience to date with this population of patients. this article concludes with a discussion of the future role of gaus and hmos in the care of ol ... | 2008 | 3815243 |
| membrane current responses of skate photoreceptors. | light-evoked membrane currents were recorded with suction electrodes from the outer segments of individual photoreceptors enzymatically dissociated from the skate retina. the intensity-response relation of dark-adapted cells closely followed a michaelis function for which a half-saturating response was elicited by a flash intensity that produced about 36 photoisomerizations. dim-light responses, as well as the early rising phase of the responses to a wide range of flash intensities, could be des ... | 2008 | 2614369 |
| forearm and wrist radiology--part i. | the emergency physician must be well versed in diagnosing forearm and wrist injuries. although many of these injuries are readily apparent, others require more sophistication to appreciate. careful attention to radiographic findings given the assistance of a well-directed history and physical examination is imperative. both the more common and the more subtle injuries are discussed. | 2008 | 2600399 |
| [modern women in their 30's]. | 2008 | 2761627 | |
| [modern women in their 30's]. | 2008 | 2761627 | |
| [myocardial perfusion during exercise and rest in coronary patients. evaluation with a thallium 201 analog (isonitrile-technetium 99 m)]. | isonitrile-technetium, a thallium 201 analog, was used for myocardial perfusion imaging in 12 patients with known coronary heart disease. 10-40 mcu of the isotope were injected at maximal effort during a bruce stress test. imaging was performed using 3 projections immediately after exercise and 24 hr later, using a gamma camera attached to a computer. myocardial necrosis was detected with a sensitivity of 89% and specificity of 63%. corresponding figures for stress induced ischemia were 89% and ... | 2008 | 2519396 |
| [current approaches to the diagnosis of immunopathologic conditions]. | 2008 | 2453710 | |
| [association of sacciform aneurysm of the renal artery and hypertension. cause or coincidence? apropos of a case]. | aneurysms of the renal artery are seldom encountered. they present as different aetiopathological types. we report the case of a female patient who had both severe arterial hypertension and an apparently dysplastic aneurysm of the right prepyelic artery. resection of the aneurysm failed to have the effect we expected on arterial hypertension. the relationship between arterial hypertension and aneurysm of the renal artery is discussed. | 2008 | 2494963 |
| [umeå, my little big city]. | 2008 | 2574927 | |
| prostate-specific antigen. superior serum marker for prostatic carcinoma. | 2008 | 2440830 | |
| pimper pimped. | 2008 | 2519529 | |
| the biology of the scid mutation. | 2008 | 2519515 | |
| [marked inhibition of transcription in mammalian cells by x-rays during disturbance of the topological continuity of superhelical dna loops]. | 2008 | 2440650 | |
| infective endocarditis in children. a seven-year experience. | eighteen children with infective endocarditis were detected over seven years. fever, gastrointestinal and chest symptoms were striking features. anaemia, elevated leukocyte count and sedimentation rate were constant laboratory findings. strep. viridans and staph. aureus were the commonest organisms isolated. we concluded that rheumatic and congenital heart disease are equally important in predisposition to infective endocarditis. | 2008 | 2519331 |
| t lymphocytes from hemophiliacs proliferate after exposure to factor viii product. | chronic exposure of hemophiliacs to allogeneic proteins via factor viii concentrate for control of bleeding could lead to a state of chronic antigen stimulation. immune function from eight hemophiliacs requiring large amounts of factor viii concentrate was assessed. it was found that 5 of 8 had a positive blastogenic response to low concentrations of factor viii in a 7-day thymidine uptake assay. separation of lymphocyte subpopulations indicated that the reactivity was contained in the t cell-en ... | 2008 | 2430365 |
| aluminum induced anemia: pathogenesis and treatment in patients on chronic hemodialysis. | the baseline hematologic status of 27 patients with modest degrees of aluminum overload was examined. in addition, hematologic data were evaluated in 19 of these patients during and after treatment with dfo. although neither severe anemia nor microcytosis was observed pretreatment, there was a significant correlation between hemoglobin level and degree of aluminum burden as determined by bone surface aluminum staining (r = -0.58; p less than 0.007). following treatment with dfo, hemoglobin conce ... | 2008 | 2615192 |
| [possibilities for purification of refuse seepage water by sand containing humic substances]. | sands containing humic substances are proposed for protection of ground water from refuse tip seepage waters which containing heavy metals and organic polluting agents. such sands are produced and spoiled southern of leipzig during uncovering of brown coal. humic acids have qualities such as ion-exchange materials, form hydrogen bondes and are able to form salts and complexes. besides they can adsorb and include other substances. this properties qualify the humic acids in contact with the graine ... | 2008 | 2525848 |
| busulfan and veno-occlusive disease of the liver. | 2008 | 2344115 | |
| submission of nucleotide sequence data to genbank. | 2008 | 2614392 | |
| [social psychiatry in private practice]. | though in general the practice of community mental health (or "social psychiatry") is a task of the state, the county or the city governments, the panel discussed two instances of sizeable contributions by private practices to the tasks of community mental health, such as crisis intervention or the care of the chronically psychiatrically handicapped, which are not commonly treated in psychiatrists' offices. the "psychosoziale arbeitsgemeinschaft" of basle began in a psychiatric group practice th ... | 2008 | 2447644 |
| a comparison of young teenage, older teenage, and adult mothers on determinants of parenting. | a nonrandom socioeconomically homogeneous convenience sample of 150 young adolescent mothers, 260 older adolescent mothers, and 242 older mothers was analyzed according to their standing on key determinants of parenting. the results of a discriminant analysis showed that the young teen mothers differed from the older mothers in terms of knowledge of child development, punitive attitudes toward childrearing, and level of depression. accuracy of classification was improved with the discriminant fu ... | 2008 | 2724173 |
| monocytic leukemoid reaction, glucocorticoid therapy, and myelodysplastic syndrome. | a leukemoid reaction is a complex and poorly understood response by the bone marrow to a variety of stresses; although any peripheral blood cell line may be involved, it is rarely a purely monocytic event. a case is reported of a true monocytic leukemoid reaction in a patient with myelodysplastic syndrome related to the effect of corticosteroids on the underlying marrow disorder. | 2008 | 2268969 |
| effects of surface tension and viscosity on airway reopening. | we studied airway opening in a benchtop model intended to mimic bronchial walls held in apposition by airway lining fluid. we measured the relationship between the airway opening velocity (u) and the applied airway opening pressure in thin-walled polyethylene tubes of different radii (r) using lining fluids of different surface tensions (gamma) and viscosities (mu). axial wall tension (t) was applied to modify the apparent wall compliance characteristics, and the lining film thickness (h) was va ... | 2008 | 2394665 |
| a comparison of dilevalol and placebo in the management of isolated systolic hypertension using ambulatory monitoring. | 1. the antihypertensive effect of dilevalol, a compound which combines beta-adrenoceptor blocking and vasodilating properties due to beta 2-adrenoceptor agonism, was studied in nineteen patients with isolated systolic hypertension (ish). a randomized, double-blind, placebo-controlled, cross-over trial with two 4 week treatment periods was used to compare the efficacy of once daily dosing with dilevalol (in the range of 100-400 mg daily) against placebo. assessment of response involved both casua ... | 2008 | 2271366 |
| [the course of varicose disease. parallel retrospective study of 2 ethnic groups (catania-basel)]. | authors presents a retrospective study with two different ethnic groups, one of them from catania and the other from basilea, with varicose veins and subjected to a saphenectomy. they studies the following parameters: age at the entrance, and when varicose veins appeared; correlation between varix appearance date and subjective symptomatology; and rapport between varix complications and its duration. the possible incidence of "ambiental factor" and contrasts between the two groups are considered ... | 2008 | 2610399 |
| quantitative hepatobiliary scintigraphy. | 2008 | 2395013 | |
| pharmacokinetics of nalbuphine during parturition. | nalbuphine hydrochloride (nubain) is a relatively new agonist-antagonist analgesic, chemically related to both oxymorphone and naloxone, which can be used as a systemic obstetric analgesic. after intravenous administration to six patients in labor at term, serial maternal serum specimens were obtained and assayed for their nalbuphine concentration. the maternal disposition of nalbuphine followed a two-compartment pharmacokinetic model, with an initial distribution phase of 4 to 20 minutes and a ... | 2008 | 3740151 |
| [prostatism. routine urography]. | 2008 | 2426824 | |
| animal models of drug self-administration by smoking. | 2008 | 2267011 | |
| extra-amniotic pregnancy. a trip to the extraembryonic coelom. | 2008 | 2277404 | |
| [extrahepatic biliary tract atresia and a common biliopancreatic canal. review of the literature apropos of a case]. | the authors report the case of an 3 months old caucasian boy which had an extrahepatic biliary atresia associate with a congenital biliary cyst and an anomalous pancreaticobiliary junction. the patency between gallbladder and duodenum permits the operative opacification of this long common pancreaticobiliary channel. the congenital biliary cyst was located on the upper part of the common bile duct and was obstructed by biliary concretions. unfortunately, no patency between intrahepatic bile duct ... | 2008 | 2268955 |
| structural aspects of pathology in alzheimer's disease. | the characteristic lesions of alzheimer's disease, neurofibrillary tangles and neuritic plaques, are the sites of accumulation of abnormal fibrillar material. the structure of the paired helical filament from tangles has been analysed by electron microscopy and biochemical studies have shown that it contains microtubule associated protein tau as a component. fibrils of beta-amyloid in the neuritic plaque arise by polymerization of a small proteolytic fragment of a much larger precursor protein. ... | 2008 | 2268679 |
| metabolism of retinoic acid and retinol by intact cells and cell extracts. | 2008 | 2292968 | |
| prediction of outcome of shunt procedures for communicating hydrocephalus. | 2008 | 2234351 | |
| tissue and subcellular distribution of endonexin, a calcium-dependent phospholipid-binding protein. | 2008 | 2151035 | |
| antibacterial, antifungal and cytotoxic activities of amblyone isolated from amorphophallus campanulatus. | to assess the in vitro antibacterial, antifungal and cytotoxic activities of amblyone, a triterpenoid isolated from amorphophallus campanulatus (roxb). | 2008 | 21264161 |
| in silico comparison of simple sequence repeats in high nucleotides-rich genomes of microorganism. | this study determined the distribution of a specific group of simple sequence repeats (ssrs), in genome sequences of 7 chromosomes (shigella flexneri 2a str 301 and 2457 t, shigella sonnei, e. coli k12, m. tuberculosis, m. leprae and s. saprophytycus) have downloaded from the genbank database for identifying abundance, distribution and composition of ssrs. the data obtained in the present study show that: (i) tandem repeats are widely distributed throughout the genomes. (ii) ssrs are differentia ... | 2008 | 19137845 |
| shigella from humans in thailand during 1993 to 2006: spatial-time trends in species and serotype distribution. | in thailand during 1993-2006, a total of 9063 shigella isolates from different medical centers were serotyped and trends over time and spatial clustering analyzed. of 3583 cases with age information, 1315 (37%) cases were from children between 0 and 4 years and 684 (19%) from children between 5 and 8 years. most infections were recorded during 1993-1994 (> 1500 per year), decreasing to < 200 in 2006. the relative species distribution also changed. during 1993-1994, shigella flexneri accounted fo ... | 2008 | 19086804 |
| increased isolation and characterization of shigella sonnei obtained from hospitalized children in tehran, iran. | shigella flexneri has been the most frequent cause of shigellosis in children in iran. to evaluate the changes in frequency of serogroups, 302 shigella species were isolated in 2003 from hospitalized children, aged less than 12 years, with acute diarrhoea in tehran, iran. the number of collected s. sonnei, s. flexneri, s. boydii, and s. dysenteriae isolates was 178 (58.9%), 110 (37.4%), 10 (3.3%), and 4 (1.3%) respectively. most (94%) s. sonnei isolates were resistant to co-trimoxazole. they wer ... | 2008 | 19069621 |
| characterization of shigella spp. by antimicrobial resistance and pcr detection of ipa genes in an infantile population from porto velho (western amazon region), brazil. | the incidence of shigella spp. was assessed in 877 infants from the public hospital in rondônia (western amazon region, brazil) where shigella represents the fourth cause of diarrhea. twenty-five isolates were identified: 18 were shigella flexneri, three shigella sonnei, three shigella boydii and one shigella dysenteriae. with the exception of s. dysenteriae, all shigella spp. isolated from children with diarrhea acquired multiple antibiotic resistances. pcr detection of ipa virulence genes and ... | 2008 | 19057826 |
| structure of the shigella t3ss effector ipah defines a new class of e3 ubiquitin ligases. | ipah proteins are e3 ubiquitin ligases delivered by the type iii secretion apparatus into host cells upon infection of humans by the gram-negative pathogen shigella flexneri. these proteins comprise a variable leucine-rich repeat-containing n-terminal domain and a conserved c-terminal domain harboring an invariant cysteine residue that is crucial for activity. ipah homologs are encoded by diverse animal and plant pathogens. here we demonstrate that the ipah c-terminal domain carries the catalyti ... | 2008 | 18997778 |
| structure of a shigella effector reveals a new class of ubiquitin ligases. | bacterial pathogens have evolved effector proteins with ubiquitin e3 ligase activities through structural mimicking. here we report the crystal structure of the shigella flexneri type iii effector ipah3, a member of the leucine-rich repeat (lrr)-containing bacterial e3 family. the lrr domain is structurally similar to yersinia pestis yopm and potentially binds to substrates. the structure of the c-terminal e3 domain differs from the typical ring- and hect-type e3s. ipah3 synthesizes a lys48-link ... | 2008 | 18997779 |
| the acrab-tolc pump is involved in multidrug resistance in clinical shigella flexneri isolates. | the two multiple-antibiotic resistance (mar) phenotypes (n = 8, respectively) and susceptible isolates (n = 4) of shigella flexneri from china were characterized involving the efflux pump acrab-tolc. the accumulation of ciprofloxacin, acrab-tolc pcr, and levels of mrna with northern blots were performed in three groups. sequencing of acrab-tolc was performed in selected isolates. an efflux inhibition was performed with phe-arg-beta-naphthylamide. the accumulation of ciprofloxacin at steady state ... | 2008 | 19035770 |
| gef-h1 mediated control of nod1 dependent nf-kappab activation by shigella effectors. | shigella flexneri has evolved the ability to modify host cell function with intracellular active effectors to overcome the intestinal barrier. the detection of these microbial effectors and the initiation of innate immune responses are critical for rapid mucosal defense activation. the guanine nucleotide exchange factor h1 (gef-h1) mediates rhoa activation required for cell invasion by the enteroinvasive pathogen shigella flexneri. surprisingly, gef-h1 is requisite for nf-kappab activation in re ... | 2008 | 19043560 |
| spa32 interaction with the inner-membrane spa40 component of the type iii secretion system of shigella flexneri is required for the control of the needle length by a molecular tape measure mechanism. | the effectors of enterocyte invasion by shigella are dependent on a type iii secretion system that contains a needle whose length average does not exceed 50 nm. previously, we reported that spa32 is required for needle length control as well as to switch substrate specificity from mxih to ipa proteins secretion. to identify functional domains of spa32, 11 truncated variants were constructed and analysed for their capacity (i) to control the needle's length; (ii) to secrete the ipa proteins; and ... | 2008 | 19019157 |
| in this issue: proteomics 20/2008. | in this issue of proteomics you will find the following highlighted articles:comprehensively confirmed annotation of short orfsduring the california gold rush, prospectors did not look only for large nuggets to pave their road to riches - they also collected gold dust. the proteomic equivalent of dust is the small orf. it does not pay to put a lower limit on dust or orf size because almost any size may be turned into "cash" or an important peptide. wei et al. demonstrate how a combination of con ... | 2008 | 18924177 |
| a pilot sheds light on secretin assembly. | 2008 | 18940600 | |
| structural characterization of the type-iii pilot-secretin complex from shigella flexneri. | assembly of the type-iii secretion apparatus, which translocates proteins through both membranes of gram-negative bacterial pathogens into host cells, requires the formation of an integral outer-membrane secretin ring. typically, a small lipidated pilot protein is necessary for the stabilization and localization of this ring. using nmr spectroscopy, we demonstrate that the c-terminal residues 553-570 of the shigella flexneri secretin mxid encompass the minimal binding domain for its cognate pilo ... | 2008 | 18940609 |
| detection of protozoan and bacterial pathogens of public health importance in faeces of corvus spp. (large-billed crow). | parasites and bacteria are reported in the faeces of birds in the current study. fresh faecal samples of the large-billed crow (corvus spp.) were collected from the study site at bangsar, an urban setting in kuala lumpur, malaysia. these samples were transported to laboratory and analysed for parasites and bacteria. pre-prepared xld agar plates were used for culturing the bacteria in the laboratory. using the api 20etm test strips, 9 different species of bacteria were identified belonging to the ... | 2008 | 18948884 |
| analysis of immune responses and serological cross reactivities among vibrio cholerae o1, shigella flexneri 2a and haemophilus influenzae b. | antigenic determinants expressed on the bacterial cell surface are of importance in the serological characterization and microbiological diagnosis. the bacterial strains carrying these identical or similar antigenic epitopes might react with antibodies produced against other strains. in this study, strong immunogenicity and antigenic cross reactivity were demonstrated among v. cholerae o1, s. flexnerii 2a and h. influenzae b surface components. the enzyme linked immunosorbent assay (elisa) resul ... | 2008 | 18954564 |
| [htpg protein of shigella flexneri 2a strain 2457t evokes inflammatory response in mice]. | to analyze the function of htpg of s. flexneri 2a 2457t, we constructed an htpg deletion mutant and a recovery mutant. | 2008 | 18837368 |
| evaluation by real-time pcr of the expression of s. flexneri virulence-associated genes ospb and phon2 under different genetical backgrounds. | under conditions of activated type iii secretion shigella flexneri up-regulates the expression of numerous genes, including the virulence plasmid (pinv)-encoded ospb and phon2 genes. ospb and phon2 are virulence-associated genes which are part of a bicistronic transcriptional unit encoding ospb, a protein (effector) of unknown function secreted by the type iii secretion (tts) apparatus, and phon2 (apyrase or atp-diphosphohydrolase), a periplasmic protein involved in polar icsa localization on th ... | 2008 | 18831939 |
| [analysis on incidence of bacillary dysentery in jinan municipality from 1951 to 2005]. | to explore the epidemic characteristics of bacterial dysentery in jinan municipality, and to provide scientific basis for effective strategy for bacterial dysentery control. | 2008 | 18844085 |
| safety and colonization of two novel virg(icsa)-based live shigella sonnei vaccine strains in rhesus macaques (macaca mulatta). | shigella are gram-negative bacterium that cause bacillary dysentery (shigellosis). symptoms include diarrhea and discharge of bloody mucoid stools, accompanied by severe abdominal pain, nausea, vomiting, malaise, and fever. persons traveling to regions with poor sanitation and crowded conditions become particularly susceptible to shigellosis. currently a vaccine for shigella has not been licensed in the united states, and the organism quickly becomes resistant to medications. during the past 10 ... | 2008 | 19793462 |
| medium- and long-latency responses to displacements of the ankle joint in patients with spinal and central lesions. | in order to elucidate further the possible pathways and the functional significance of long-loop reflexes we recorded short-, medium- and long-latency responses from leg muscles in 27 patients with spinal lesions, 20 patients with central lesions of the internal capsule or cerebral hemisphere, and in 18 control patients with frontal or occipital lesions without motor or sensory disturbances. our normal population included 50 subjects, who were age and sex matched to the patients. the mean latenc ... | 2008 | 2580691 |
| alpha-fetoprotein-producing renal cell carcinoma. | a case of alpha-fetoprotein (afp)-producing renal cell carcinoma with multiple bone and lung metastases, but without liver involvement is reported. the stain specific to afp (avidin-biotin complex) proved the presence of the afp in the cytoplasms of some cells of the renal tumors. in addition, three other cases of aff-producing renal cancer recently published in the literature in japan are reviewed. these four cases indicate that mesoderm-originating malignant tumors such as renal cell carcinoma ... | 2008 | 2446735 |
| [clinical study of osteoporosis]. | 2008 | 2614196 | |
| comparison of nonsteroidal anti-inflammatory drugs, ibuprofen and flurbiprofen, with methylprednisolone and placebo for acute pain, swelling, and trismus. | pain, swelling, loss of function, and hyperthermia are acute postoperative sequelae of inflammation due to tissue injury during surgical procedures. pharmacologic strategies for minimizing the clinical manifestations of surgical trauma are often directed toward blocking the formation or inhibiting the effects of the biochemical mediators of acute inflammation. this study compared two nonsteroidal anti-inflammatory drugs (nsaids), flurbiprofen and ibuprofen, with a prototype glucocorticoid, methy ... | 2008 | 2395047 |
| contempo '90. | 2008 | 2329645 | |
| similarities in the repair kinetics of sublethal and potentially lethal x-ray damage in log phase chinese hamster v79 cells. | we have compared the repair kinetics of x-ray-induced sublethal damage (sld) and potentially lethal damage (pld) in v79 cells during postirradiation incubation in growth medium at 37 degrees c. kinetics of sld repair were studied by dose fractionation (d1 + d2 = 2 + 2, 4 + 2, 4 + 4, 10 + 4 and 10 + 7 gy). kinetics of pld repair were studied by incubating cells with 0.5 m hypertonic saline (hs) for 20 min at various times after irradiation. the repair of sld, after 2, 4 and 10 gy, was complete in ... | 2008 | 2570810 |
| indicator dilution time-activity curves demonstrated by rapid magnetic resonance imaging techniques and paramagnetic contrast agent. | indicator dilution time-activity curves are demonstrated using magnetic resonance imaging (mri) as the detector and a paramagnetic contrast agent as the indicator. manganese chloride was injected into a flow phantom. the nuclear magnetic resonance (mr) intensity was measured downstream. several flow rates were used. the observed mr intensity decreased as the paramagnetic indicator passed through the imaging plane. the qualitative changes of the mr intensity decrease varied in accordance with ind ... | 2008 | 2663765 |
| multiple zones in the sequence of calreticulin (crp55, calregulin, hacbp), a major calcium binding er/sr protein. | the complete amino acid sequence of crp55, the major 55 kd calcium binding protein of the er lumen, was deduced from the murine cdna nucleotide sequence. this was completed using a novel application of pcr amplification. the mature 399 residue protein encoded is preceded by a 17 amino acid leader sequence and ends in the er signal sequence, kdel. the protein contains no calcium binding motifs of the ef hand type or of the form seen in calelectrin-related proteins. the major region of potential l ... | 2008 | 2583110 |
| multiple zones in the sequence of calreticulin (crp55, calregulin, hacbp), a major calcium binding er/sr protein. | the complete amino acid sequence of crp55, the major 55 kd calcium binding protein of the er lumen, was deduced from the murine cdna nucleotide sequence. this was completed using a novel application of pcr amplification. the mature 399 residue protein encoded is preceded by a 17 amino acid leader sequence and ends in the er signal sequence, kdel. the protein contains no calcium binding motifs of the ef hand type or of the form seen in calelectrin-related proteins. the major region of potential l ... | 2008 | 2583110 |
| [minimal monitoring in the operating room]. | 2008 | 2782684 | |
| [minimal monitoring in the operating room]. | 2008 | 2782684 | |
| [what intensity of the incisional pain in the postoperative period?]. | 2008 | 2576331 | |
| [a study of bronchial sensitivity and bronchial reactivity using astograph and transcutaneous oxygen tension in asthmatic children. the problems of simultaneous measurement]. | bronchial sensitivity and reactivity in 60 patients with bronchial asthma was measured using the astograph and simultaneous transcutaneous oxygen tension [ptco2]. in spite of increasing respiratory resistance, there were some cases in which ptco2 did not show remarkable decrease. the ptco2 percentage was defined as (basal value of ptco2 - bottom value of ptco2)/(basal value of ptco2). the correlation between ptco2% and the basal value of ptco2 was relatively high (r = 0.42, n = 58, p less than 0 ... | 2008 | 2584366 |
| a comparative clinical trial of duodenal ulcer healing with two regimens of cimetidine: 800 mg once nightly and 400 mg twice daily. | the efficacy and safety of two dosage regimens of cimetidine were compared in a single-blind study of 50 adults with endoscopically proven duodenal ulcers. patients were randomly allocated to receive 800 mg cimetidine taken once nightly or 400 mg cimetidine taken twice daily for 4 weeks. following 4 weeks' treatment patients again underwent endoscopy and, if healing was incomplete, they received a further 4 weeks' treatment. at 4 weeks, healing occurred in 21/25 (84%) patients on the once-daily ... | 2008 | 2257964 |
| [myopathy in the uremic patient: apropos of a case]. | uremic myopathy is relatively unknown, despite the fact that it can be quite a severe handicap. it is a non-specific proximal myopathy which must be distinguished from uremic polyneuropathy. several disorders linked to renal insufficiency have been implicated, but these only play an adjuvant role with regard to renal osteodystrophy. indeed the presence of myopathy in cases of severe osteodystrophy, its similarity to the myopathies associated with different types of osteomalacia and hyperparathyr ... | 2008 | 2633067 |
| risk areas and neighborhood-level risk factors for shigella dysenteriae 1 and shigella flexneri. | annually, there are 165 million cases of shigellosis resulting in 1.1 million deaths in the developing world. two species of the causative agent, shigella dysenteriae 1 and shigella flexneri, are responsible for acute diarrheal illness. vaccines are being developed against both but many questions remain about the disease burden, distribution of species in space and time, and community-level risk factors. this study answers two questions. what are the differences in neighborhood-level risk factor ... | 2008 | 17602851 |
| isolation and antibiotic susceptibility of salmonella and shigella strains isolated from children in gaza, palestine from 1999 to 2006. | diarrhea and acute gastroenteritis are among the leading causes of illnesses and death in infants and children throughout the world, especially in developing countries, globally, salmonella and shigella remain the major contributors to acute enteric infections and diarrhea. | 2008 | 17854424 |
| identification of newly recognized serotype 1c as the most prevalent shigella flexneri serotype in northern rural vietnam. | we investigated the identity of 37 shigella flexneri strains that had previously been isolated from northern rural vietnam (son tay province) and described as untypable. twenty-four isolates reacted with masf 1c, a monoclonal antibody specific for s. flexneri serotype 1c. a further ten untypable isolates were found to be rough mutants (no longer expressing o-antigen) that were derived from serotype 1c strains. pulsed-field gel electrophoresis demonstrated that these strains consisted of many dif ... | 2008 | 17922932 |
| a role for nod-like receptors in autophagy induced by shigella infection. | shigella infection, the cause of bacillary dysentery, induces caspase-1 activation and cell death in macrophages, but the precise mechanisms remain poorly understood. in our recent study, we presented evidence that caspase-1 activation and il-1beta processing induced by shigella are mediated through ipaf, a cytosolic pattern-recognition receptor of the nucleotide-binding oligomerization domain (nod)-like receptor (nlr) family and the adaptor protein apoptosis-associated speck-like protein contai ... | 2008 | 17932464 |
| synthesis, characterization and antibacterial activity of cobalt(iii) complexes with pyridine-amide ligands. | the ligands 2-(n-(x-pyridyl)carbamoyl)pyridine (x=2, 3 or 4 for hl1-hl3, respectively) and 2,6-bis(n-(y-pyridyl)carbamoyl)pyridine (y=2, 3 or 4 for h2l4-h2l6, respectively) in their mono- and di-deprotonated forms have been used to synthesize kinetically stable cobalt(iii) compounds [co(l1-3)3] (1-3) and na[co(l4-6)2] (4-6), respectively. the co(iii) ion is in octahedral environment and is surrounded by three bidentate ligands in complexes 1-3 and two tridentate ligands in complexes 4-6. ligands ... | 2008 | 17959275 |
| the pattern-recognition molecule nod1 is localized at the plasma membrane at sites of bacterial interaction. | the pattern-recognition molecule nod1 is a critical sensor for bacterial derived diaminopimelic acid-containing peptidoglycan fragments which induces innate immune responses in epithelial cells. here we report the subcellular localization of this protein in human epithelial cells. nod1 is localized in the cytosol and at the plasma membrane in human cells. this membrane association is dependent on the integrity of the protein, on its signalling capacity and on an intact actin cytoskeleton. signal ... | 2008 | 17970764 |
| the nlee/ospz family of effector proteins is required for polymorphonuclear transepithelial migration, a characteristic shared by enteropathogenic escherichia coli and shigella flexneri infections. | enteropathogenic escherichia coli (epec) and shigella flexneri are human host-specific pathogens that infect intestinal epithelial cells. however, each bacterial species employs a different infection strategy within this environmental niche. epec attaches to the apical surface of small intestine enterocytes, causing microvillus effacement and rearrangement of the host cell cytoskeleton beneath adherent bacteria. in contrast, s. flexneri invades the large intestine epithelium at the basolateral m ... | 2008 | 17984206 |
| saccharomyces boulardii interferes with shigella pathogenesis by postinvasion signaling events. | saccharomyces boulardii is gaining in popularity as a treatment for a variety of diarrheal diseases as well as inflammatory bowel disease. this study was designed to examine the effect of this yeast on infection by shigella flexneri, a highly infectious and human host-adapted enteric pathogen. we investigated key interactions between the bacteria and host cells in the presence of the yeast in addition to a number of host responses including proinflammatory events and markers. although the presen ... | 2008 | 18032477 |
| muramylpeptide shedding modulates cell sensing of shigella flexneri. | bacterial infections trigger the activation of innate immunity through the interaction of pathogen-associated molecular patterns (pamps) with pattern recognition molecules (prms). the nucleotide-binding oligomerization domain (nod) proteins are intracellular prms that recognize muramylpeptides contained in peptidoglycan (pgn) of bacteria. it is still unclear how nod1 physically interacts with pgn, a structure internal to the gram-negative bacterial envelope. to contribute to the understanding of ... | 2008 | 18042252 |