Publications

TitleAbstractYear(sorted descending)
Filter
PMID
Filter
antimicrobial protein from streptomyces fulvissimus inhibitory to methicillin resistant staphylococcus aureus.fermented culture of streptomyces fulvissimus was found to secrete an antibacterial protein inhibitory to micrococcus luteus, bacillus subtilis, bacillus cereus and methicillin resistant staphylococcus aureus (mrsa) strains. the extracellular protein from the fermented culture on concentration revealed a high molecular weight peptide of 63kda on sds-page gel and the region on gel displayed inhibitory activity against methicillin resistant staphylococcus aureus. bioactivity of the extra cellular ...200818512335
collagen's triglycine repeat number and phylogeny suggest an interdomain transfer event from a devonian or silurian organism into trichodesmium erythraeum.two competing effects at two vastly different scales may explain collagen's current translation length. the necessity to have long molecules for maintaining mechanical integrity at the organism and supraorganism scales may be limited by the need to have small molecules capable of robust self-assembly at the nanoscale. the triglycine repeat regions of all 556 currently cataloged organisms with collagen-like genes were ranked by length. this revealed a sharp boundary in the gxy transcript number a ...200818521530
ecological consequences of ingestion of bacillus cereus on bacillus thuringiensis infections and on the gut flora of a lepidopteran host.the bacillus cereus group comprises a diverse array of non-pathogenic bacteria as well as pathogens such as bacillus thuringiensis. their spores are found together in soil and leaves and are therefore likely to commonly interact within hosts. mixed infections of pathogenic b. thuringiensis and non-pathogenic strains have been little studied, despite their potential impact on biological control and the evolutionary ecology of virulence. antibiotic secreting strains of b. cereus have been shown to ...200818533180
the combined effects of high pressure and nisin on germination and inactivation of bacillus spores in milk.the aim of this work was to investigate the germination and inactivation of spores of bacillus species in buffer and milk subjected to high pressure (hp) and nisin.200818248377
alkyl deoxy-arabino-hexopyranosides: synthesis, surface properties, and biological activities.octyl and dodecyl glycosides possessing 2-deoxy-arabino-hexopyranoside moieties belonging to the d- and l-series in their alpha- and beta-forms were synthesized by reaction of an acetyl protected glycal with octanol or dodecanol, catalyzed by triphenylphosphine hydrobromide, followed by deprotection. their surface properties were studied and discussed in terms of the adsorption and aggregation parameters, pc(20), cmc, and gamma(cmc). the antimicrobial activities were assessed using the paper dis ...200818249550
evaluation of in vitro cr(vi) reduction potential in cytosolic extracts of three indigenous bacillus sp. isolated from cr(vi) polluted industrial landfill.three efficient cr(vi) reducing bacterial strains were isolated from cr(vi) polluted landfill and characterized for in vitro cr(vi) reduction. phylogenetic analysis using 16s rrna gene sequencing revealed that the newly isolated strains g1dm20, g1dm22 and g1dm64 were closely related to bacillus cereus, bacillus fusiformis and bacillus sphaericus, respectively. the suspended cultures of all bacillus sp. exhibited more than 85% reduction of 1000 microm cr(vi) within 30 h. the suspended culture of ...200818255287
antibacterial and antifungal activities of different parts of tribulus terrestris l. growing in iraq.antimicrobial activity of organic and aqueous extracts from fruits, leaves and roots of tribulus terrestris l., an iraqi medicinal plant used as urinary anti-infective in folk medicine, was examined against 11 species of pathogenic and non-pathogenic microorganisms: staphylococcus aureus, bacillus subtilis, bacillus cereus, corynebacterium diphtheriae, escherichia coli, proteus vulgaris, serratia marcescens, salmonella typhimurium, klebsiella pneumoniae, pseudomonas aeruginosa and candida albica ...200818257138
expression and characterization of aiia gene from bacillus subtilis bs-1.ahl-lactonase (aiia), a metallo-beta-lactamase produced by bacillus thuringiensis, bacillus cereus and bacillus anthracis, specifically hydrolyzes n-acyl-homoserine lactones (ahls) secreted by gram-negative bacteria and thereby attenuates the symptoms caused by plant pathogens. in this study, an aiia gene was cloned from bacillus subtilis bs-1 by pcr with a pair of degenerate primers. the deduced 250 amino acid sequence contained two small conserved regions, 103shlhfdh109 and 166tpghtpgh173, whi ...200818261893
bacillus cereus induces permeability of an in vitro blood-retina barrier.most bacillus cereus toxin production is controlled by the quorum-sensing-dependent, pleiotropic global regulator plcr, which contributes to the organism's virulence in the eye. the purpose of this study was to analyze the effects of b. cereus infection and plcr-regulated toxins on the barrier function of retinal pigment epithelium (rpe) cells, the primary cells of the blood-retina barrier. human arpe-19 cells were apically inoculated with wild-type or quorum-sensing-deficient b. cereus, and cyt ...200818268029
glycoconjugates enhanced the intracellular killing of bacillus spores, increasing macrophage viability and activation.infections caused by bacillus spores can be attenuated if the intracellular killing of the organism by macrophages can be enhanced. glycoconjugate-bearing polymers, which selectively bind to bacillus spores, were tested for modulation of intracellular killing when added prior to, during, and following macrophage exposure to b. cereus spores. in the absence of glycoconjugates, murine macrophages were ineffective at killing bacillus spores. in presence of glycoconjugates, however, macrophages effi ...200818270686
expression of functional bacillus spoiisab toxin-antitoxin modules in escherichia coli.spoiisa and spoiisb proteins from bacillus subtilis belong to a recently described bacterial programmed-cell death system. the current work demonstrates that the toxin-antitoxin module is also functional in escherichia coli cells, where the expression of spoiisa toxin leads to transient growth arrest coupled with cell lysis, and spoiisa-induced death can be prevented by coexpression of its cognate antitoxin, spoiisb. escherichia coli cells appear to be able to escape the spoiisa killing by activ ...200818096016
evaluation of standard and new chromogenic selective plating media for isolation and identification of bacillus cereus.in this study, the performance of two new chromogenic plating media (cbc and bcm) was compared with two standard selective plating media (pemba and myp) recommended by food authorities for isolation, identification and enumeration of bacillus cereus. the four media types were challenged with a strain set comprising 100 b. cereus isolates from different origins and with different toxigenic potentials (40 food isolates, 40 isolates from food borne outbreaks and 20 clinical isolates). additionally, ...200818055052
self-transfer and mobilisation capabilities of the pxo2-like plasmid pbt9727 from bacillus thuringiensis subsp. konkukian 97-27.recent characterisations of plasmids related to the anthrax virulence plasmids pxo1 and pxo2 in clinical isolates of bacillus cereus and bacillus thuringiensis have contributed to the emerging picture of a virulence-associated plasmid pool in the b. cereus sensu lato group. the family of pxo2-like plasmids includes the conjugative plasmid paw63 from the biopesticide strain b. thuringiensis subsp. kurstaki hd73 and the heretofore cryptic plasmid pbt9727 from the clinical strain b. thuringiensis s ...200818272219
glycosyltransferase: a specific marker for the discrimination of bacillus anthracis from the bacillus cereus group.bacillus anthracis, the aetiological agent of anthrax, has been taxonomically classified with the bacillus cereus group, which comprises b. cereus, bacillus thuringiensis, bacillus mycoides, bacillus pseudomycoides and bacillus weihenstephanensis. although the pathogenesis and ecological manifestations may be different, b. anthracis shares a high degree of dna sequence similarity with its group member species. as a result, the discrimination of b. anthracis from its close relatives in the b. cer ...200818287289
diorganotin(iv) complexes of dipeptides containing the alpha-aminoisobutyryl residue (aib): preparation, structural characterization, antibacterial and antiproliferative activities of [(n-bu)2 sn(h(-1)l)] (lh=h-aib-l-leu-oh, h-aib-l-ala-oh).two new organotin(iv) complexes with dianionic dipeptides containing the alpha-aminoisobutyryl residue (aib) as ligands are described. the solid complexes [(n-bu)(2)sn(h(-1)l(a))] x 2meoh (1 x 2meoh) (l(a)h=h-aib-l-leu-oh) and [(n-bu)(2)sn(h(-1)l(b))] x meoh (2 x meoh) (l(b)h=h-aib-l-ala-oh) have been isolated and characterized by single-crystal x-ray crystallography and spectroscopic techniques (h(-1)l(2-) is the dianionic form of the corresponding dipeptide). complexes 1 x 2meoh and 2 x meoh a ...200818289688
antimicrobial triterpenoids from vladimiria muliensis.a new triterpenoid with a rearranged ursane skeleton, 3beta-acetoxyl-11alpha-methoxybauer-8-en-7alpha-ol ( 1), two new ursane triterpenoids, 1alpha,5alpha-dioxy-11alpha-hydroxyurs-12-en-3-one ( 2) and urs-3beta,13alpha,18beta-triol ( 3), together with three known ursane triterpenoids ( 4- 6) were isolated from the rhizome of vladimiria muliensis. their structures were elucidated on the basis of spectroscopic methods (ir, eims, hresims, 1d and 2d nmr, and x-ray crystallography diffraction). compo ...200818293903
endophthalmitis caused by bacillus species.to investigate clinical settings, management, and visual outcomes of endophthalmitis caused by bacillus species and to review in vitro effectiveness of antibiotics commonly used against bacillus species.200818295182
role of ureolytic activity in bacillus cereus nitrogen metabolism and acid survival.the presence and activities of urease genes were investigated in 49 clinical, food, and environmental bacillus cereus isolates. ten strains were shown to have urease genes, with eight of these strains showing growth on urea as the sole nitrogen source. two of the urease-positive strains, including the sequenced strain atcc 10987, could not use urea for growth, despite their capacities to produce active urease. these observations can be explained by the inability of the two strains to use ammoniu ...200818296540
wet and dry density of bacillus anthracis and other bacillus species.to determine the wet and dry density of spores of bacillus anthracis and compare these values with the densities of other bacillus species grown and sporulated under similar conditions.200818298528
bacillus cereus nhe is a pore-forming toxin with structural and functional properties similar to the clya (hlye, shea) family of haemolysins, able to induce osmotic lysis in epithelia.the mechanism by which bacillus cereus causes diarrhoea is unknown. three putative enterotoxins have been proposed, haemolysin bl (hbl), cytotoxin k and non-haemolytic enterotoxin (nhe). both hbl and nhe are three-component cytotoxins and maximal cytotoxicity of nhe against epithelia is dependent on all three components. however, little is known of the mechanism of cytotoxicity. markers of plasma membrane disruption, namely propidium iodide uptake, loss of cellular atp and release of lactate deh ...200818310016
synthesis and biological evaluation of diversely substituted indolin-2-ones.the synthesis of indolin-2-one derivatives substituted in the 3-position by an aminomethylene group bearing either an ornithine or a lysine residue is described. the inhibitory activities of these compounds toward a panel of eight kinases were examined. furthermore, the antibacterial activities of the prepared compounds were tested against two gram-positive bacteria bacillus cereus and streptomyces chartreusis, a gram-negative bacterium escherichia coli and a yeast candida albicans.200818313174
biosorption of nickel, chromium and zinc by merp-expressing recombinant escherichia coli.escherichia coli hosts able to over-express metal-binding proteins (merp) originating from gram-positive (bacillus cereus rc607) and gram-negative (pseudomonas sp. k-62) bacterial strains were used to adsorb ni(2+), zn(2+) and cr(3+) in aqueous solutions. the initial adsorption rate and adsorption capacity were determined to evaluate the performance of the biosorbents. with the expression of merp protein, the metal adsorption capacity of the recombinant strains for ni(2+), zn(2+) and cr(3+) sign ...200818313216
chemical composition, and antioxidant and antimicrobial activities of three hazelnut (corylus avellana l.) cultivars.hazelnut (corylus avellana l.) is a very popular dry fruit in the world being consumed in different form and presentations. in the present work, three hazelnut cultivars (cv. daviana, fertille de coutard and m. bollwiller) produced in portugal, were characterized in respect to their chemical composition, antioxidant potential and antimicrobial activity. the samples were analysed for proximate constituents (moisture, fat, crude protein, ash), nutritional value and fatty acids profile by gc/fid. a ...200818316150
etest for antibiotic susceptibility testing of bacillus anthracis, bacillus cereus and bacillus thuringiensis: evaluation of a french collection. 200818316178
functionality of a bacillus cereus biological agent in response to physiological variables encountered in aquaculture.the potential of a bacillus cereus isolate (nrrl 100132) as a biological agent for aquaculture has been demonstrated in vitro and in vivo. the functionality of this isolate across a range of physiological conditions, including salinity, ph and temperature, based on rearing of high-value ornamental cyprinus carpio, was investigated. temperature had a significant influence on germination, specific growth rate and increase in cell number of b. cereus in shake-flask cultures, whilst salinity and ph ...200818317748
genus-wide bacillus species identification through proper artificial neural network experiments on fatty acid profiles.gas chromatographic fatty acid methyl ester analysis of bacteria is an easy, cheap and fast-automated identification tool routinely used in microbiological research. this paper reports on the application of artificial neural networks for genus-wide fame-based identification of bacillus species. using 1,071 fame profiles covering a genus-wide spectrum of 477 strains and 82 species, different balanced and imbalanced data sets have been created according to different validation methods and model pa ...200818322819
purification, crystallization and preliminary x-ray analysis of the peptidoglycan n-acetylglucosamine deacetylase bc1960 from bacillus cereus in the presence of its substrate (glcnac)6.the peptidoglycan n-acetylglucosamine (glcnac) deacetylase bc1960 from bacillus cereus (ec 3.5.1.33), an enzyme consisting of 275 amino acids, was crystallized in the presence of its substrate (glcnac)(6). the crystals belonged to the tetragonal space group p4(1)2(1)2, with unit-cell parameters a = b = 92.7, c = 242.9 a and four molecules in the asymmetric unit. a complete data set was collected at 100 k to a resolution of 2.38 a using synchrotron radiation.200818323609
effects of rosa rugosa petals on intestinal bacteria.the effects of pulverized petal of rosa rugosa on the growth of 10 species of intestinal and pathogenic bacteria were investigated. growth of bifidobacteria and lactobacilli was not affected by the addition of the petal in plate cultivation. however, the growth of bacteroides vulgatus, escherichia coli, staphylococcus aureus, and bacillus cereus was completely inhibited by the addition of 0.1, 0.5, 0.1, and 0.05% (w/v) of the petal respectively. in liquid cultivation, the addition of the petal ( ...200818323655
crystal structure of the clostridium limosum c3 exoenzyme.c3-like toxins adp-ribosylate and inactivate rho gtpases. seven c3-like adp-ribosyltransferases produced by clostridium botulinum, clostridium limosum, bacillus cereus and staphylococcus aureus were identified and two representatives--c3bot from c. botulinum and c3stau2 from s. aureus--were crystallized. here we present the 1.8a structure of c. limosum c3 transferase c3lim and compare it to the structures of other family members. in contrast to the structure of apo-c3bot, the canonical adp-ribos ...200818325337
growth inhibitory effects of kimchi (korean traditional fermented vegetable product) against bacillus cereus, listeria monocytogenes, and staphylococcus aureus.kimchi is a unique korean traditional vegetable product that is fermented by lactic acid bacteria (lab) and is mainly consumed as a side dish with boiled rice. its main ingredients are brined chinese cabbage, red pepper powder, and fermented fish sauce, and these are combined with many spices such as garlic, green onion, ginger, and some seaweed. the relationship between the concentration of lab or the ph and the growth of three gram-positive foodborne pathogens (bacillus cereus, listeria monocy ...200818326182
insecticidal properties and microbial contaminants in a spodoptera exigua multiple nucleopolyhedrovirus (baculoviridae) formulation stored at different temperatures.the spodoptera exigua (hübner) multiple nucleopolyhedrovirus (semnpv) is currently being tested as a biological insecticide for use in greenhouse crops in southern spain. we performed a study in which semipurified semnpv occlusion bodies (obs) were formulated in phosphate-buffered saline, ph 6.5, with 5% (vol:vol) glycerol and 0.15% (wt:vol) sorbic acid, and they were stored at -20, 4, or 25 degrees c during 18 mo. initial aerobic counts (+/-se) averaged 1.4 (+/-0.17) x 10(7) colony-forming unit ...200818330114
bioactive properties and chemical composition of six walnut (juglans regia l.) cultivars.the chemical composition, antioxidant potential and antimicrobial activity were studied in six walnuts (juglans regia l.) cultivars (cv. franquette, lara, marbot, mayette, mellanaise and parisienne) produced in portugal. concerning their chemical composition the main constituent of fruits was fat ranging from 78.83% to 82.14%, being the nutritional value around 720kcal per 100g of fruits. linoleic acid was the major fatty acid reaching the maximum value of 60.30% (cv. lara) followed by oleic, li ...200818334279
quantifying the reproduction of bacillus thuringiensis hd1 in cadavers and live larvae of plutella xylostella.the bacillus cereus group comprises a range of micro-organisms with diverse habits, including gut commensals, opportunistic pathogens and soil saprophytes. using quantitative microbiological methods we tested whether bacillus thuringiensis (bt) could reproduce in cadavers of plutella xylostella killed by bt, or in the gut of live insects, or be transmitted vertically from females to their offspring. we also tested whether diverse bt strains could grow in high nutrient broth at a ph similar to th ...200818336832
synthesis, characterization and biological aspects of novel five-coordinated dimeric-cu(ii) systems.the structural and spectroscopic properties of novel five-coordinated dimeric-cu(ii) system have been investigated. the biocidal activities of all eight compounds, ligands, cupric nitrate and standard drugs against six bacteria and three fungi were determined. the dna interaction activity of complexes was studied using spectrophotometry and electrophoresis. the superoxide dismutase (sod)-like activity of the complexes was compared with previously reported monomeric- and dimeric copper complexes. ...200818341262
qnr-like pentapeptide repeat proteins in gram-positive bacteria.to study the role of qnr-like pentapeptide repeat proteins (prps) from several gram-positive species with quinolone resistance in vitro.200818343805
iron(iii) complexes: preparation, characterization, antibacterial activity and dna-binding.iron(iii) have been combined to well known quinolones (ciprofloxacin) and some schiff bases with the help of coordination approach. characterization of these compounds have been done using elemental analysis, magnetic measurements, thermogravimetric analysis, ir, uv-vis, (1)h nmr and (13)c nmr spectral investigation. analytical studies suggest that the iron(iii)-quinolone complexes assume a six-coordinated dimeric distorted octahedral geometry. all the compounds show a good antibacterial activit ...200818343909
physico-chemical and hygienic property modifications of stainless steel surfaces induced by conditioning with food and detergent.the effect of repeated conditioning procedures (25 runs), consisting of soiling (milk and meat products) and cleaning steps, on the hygienic status, physico-chemical properties and surface chemical composition of stainless steel (ss) surfaces, was investigated. five sss differing in grade and finish were used. both soiling and surface cleaning/conditioning procedures resulted in a similar increase in the surface contamination with carbon, while the changes in the basic component of the surface f ...200818348006
dissemination of bacillus cereus in a paediatric intensive care unit traced to insufficient disinfection of reusable ventilator air-flow sensors.over a two-week period in november 2006, vancomycin-resistant bacillus cereus was isolated from respiratory samples from six ventilated paediatric intensive care unit (picu) patients. to investigate the possibility of a common source and extent of the dissemination, all procedures related to mechanical ventilation were monitored and surveillance cultures performed. b. cereus was isolated from reusable air-flow sensors, before and after on-site disinfection with 70% alcohol. the organism was also ...200818358564
antimicrobial activity of miconia species (melastomataceae).this work evaluated the antimicrobial activity of the methanol and chloroform extracts of the leaves of miconia cabucu, miconia rubiginosa, and miconia stenostachya using the disc-diffusion method. the results obtained showed that the methanol extracts of the leaves of m. rubiginosa and m. stenostachya and the chloroform extract of the leaves of m. cabucu presented antimicrobial activity against the tested microorganisms.200818361747
bacillus cereus peritonitis after cesarean section. 200818363475
heat resistance of bacillus cereus emetic toxin, cereulide.the study describes the effects of heating temperature and exposure time on the thermal stability of cereulide under different conditions (ph, presence/absence of oil phase and cereulide concentration).200818363653
the electrostatic driving force for nucleophilic catalysis in l-arginine deiminase: a combined experimental and theoretical study.l-arginine deiminase (adi) catalyzes the hydrolysis of l-arginine to form l-citrulline and ammonia via two partial reactions. a working model of the adi catalytic mechanism assumes nucleophilic catalysis by a stringently conserved active site cys and general acid-general base catalysis by a stringently conserved active site his. accordingly, in the first partial reaction, the cys attacks the substrate guanidino c zeta atom to form a tetrahedral covalent adduct, which is protonated by the his at ...200818366187
rapid polymerase chain reaction-based screening assay for bacterial biothreat agents.to design and evaluate a rapid polymerase chain reaction (pcr)-based assay for detecting eubacteria and performing early screening for selected class a biothreat bacterial pathogens.200818370996
in vitro toxicity of cereulide on porcine pancreatic langerhans islets.cereulide is a k(+) ionophore cytotoxic and mitochondriotoxic to primary cells and cell lines of human and other mammalian origins. it is a heat-stable, highly lipophilic (logk(ow) 5.96) peptide (1152 g mol(-1)) produced by certain strains of bacillus cereus, a bacterium connected to emetic food poisonings. in this study the pancreatic toxicity of purified cereulide, and cereulide-containing bacterial extracts, was studied using fetal porcine langerhans islets in culture. exposure to 1ngml(-1) o ...200818374382
the antimicrobial efficacy of plant essential oil combinations and interactions with food ingredients.the objective of this study was to evaluate the efficacy of plant essential oils (eos) in combination and to investigate the effect of food ingredients on their efficacy. the eos assessed in combination included basil, lemon balm, marjoram, oregano, rosemary, sage and thyme. combinations of eos were initially screened against bacillus cereus, escherichia coli, listeria monocytogenes and pseudomonas aeruginosa using the spot-on-agar test. the influence of varying concentrations of eo combinations ...200818378032
toward improving therapeutic regimens for bacillus endophthalmitis.bacillus cereus causes the most virulent and refractory form of endophthalmitis. the authors analyzed the effectiveness of early treatment with vancomycin or gatifloxacin, with or without dexamethasone, for experimental b. cereus endophthalmitis.200818385066
identification of novel hora-harbouring bacteria capable of spoiling beer.an atp-binding cassette (abc) multi-drug resistance (mdr) gene was found in 4 gram-positive bacterial isolates of environmental origin and found capable of spoiling beer. the bacteria isolated were bacillus cereus, bacillus licheniformis, paenibacillus humicus, and staphylococcus epidermidis; all of which were previously unappreciated as beer-spoilage bacteria. the mdr gene found in these bacteria has less than 37% similarity to known abc mdr proteins described for bacillus and staphylococcus, a ...200818389005
decontamination of fluid milk containing bacillus spores using commercial household products.although commercial sanitizers can inactivate bacterial spores in food processing environments, relatively little data exist as to the decontamination of products and surfaces by consumers using commercial household products. should a large scale bioterrorism incident occur in which consumer food products were contaminated with a pathogenic sporeformer such as bacillus anthracis, there may be a need to decontaminate these products before disposal as liquid or solid waste. studies were conducted ...200818389688
potential sources of microbial contamination of satsuma mandarin fruit in japan, from production through packing shed.potential sources of microbial contamination of satsuma mandarin fruit were investigated from production through the packing shed in the 2005 season. microbial counts in the peel and flesh during the fruit development stage were below 2.4 log cfu/g for bacteria and 3 log cfu/g for fungi, except for the peel in august and september. in the field environment, the highest microbial counts were found in fallen leaves on the ground, followed by soil, organic fertilizer, and agricultural water. only t ...200818389696
microbiological evaluation of stuffed mussels.stuffed mussel is a traditional food, sold by street vendors in coastal parts of turkey and other mediterranean countries. in the present study, the microbiological quality of not only the stuffing mixture, but also the outer surface of the stuffed mussels was evaluated for 1 year, and the effect of the ambient temperatures on the prevalence and the count levels of the microorganisms were evaluated. fifty samples (750 stuffed mussels in total) were collected periodically, and microbiological ana ...200818389710
structure of the exosporium and sublayers of spores of the bacillus cereus family revealed by electron crystallography.we report on the first step in mapping out the spatial location of structural proteins within the exosporium, namely a description of its three-dimensional architecture. using electron microscopy and image analysis, we have characterized crystalline fragments from the exosporium of bacillus cereus, b. thuringiensis and b. anthracis strains and identified up to three distinct crystal types. type i and type ii crystals were examined in three dimensions and shown to form arrays of interlinked crown ...200818399937
interactions of some common pathogenic bacteria with acanthamoeba polyphaga.protozoan grazing is a major trophic pathway whereby the biomass re-enters the food web. nonetheless, not all bacteria are digested by protozoa and the number known to evade digestion, resulting in their environmental augmentation, is increasing. we investigated the interactions of bacillus cereus, enterococcus faecalis, enteropathogenic escherichia coli (epec), listeria monocytogenes, salmonella enterica serovar typhimurium, and methicillin-sensitive staphylococcus aureus (mssa), with the amoeb ...200818399997
the antibacterial activity against mrsa strains and other bacteria of a <500da fraction from maggot excretions/secretions of lucilia sericata (diptera: calliphoridae).the application of lucilia sericata larvae to chronic, infected wounds results in the rapid elimination of infecting microorganisms, including mrsa. previously, we demonstrated in vitro antibacterial activity of native excretions/secretions (nes) from l. sericata and partially purified two low mass antibacterial compounds with masses of 0.5-10kda and <500da. the present study reports the antibacterial effects of the <500da fraction (es<500) on the growth and morphology of a range of bacteria, in ...200818400544
two new antibacterial norabietane diterpenoids from cyanobacteria, microcoleous lacustris.two abietane diterpenes were isolated from cyanobacteria microcoleous lacustris, 20-nor-3alpha-acetoxyabieta-5,7,9,11,13-pentaene and 20-nor-3alpha-acetoxy-12-hydroxy-abieta-5,7,9,11,13-pentaene. these compounds were assayed against staphylococcus aureus, staphylococcus epidermidis, salmonella typhi, vibrio cholerae, bacillus subtilis, bacillus cereus, escherichia coli, and klebsiella pneumoniae. both compounds showed activity against s. aureus, s. epidermidis, s. typhi, and v. cholerae, but not ...200818404301
comparative analysis of the diversity of aerobic spore-forming bacteria in raw milk from organic and conventional dairy farms.bacterial contamination of raw milk can originate from different sources: air, milking equipment, feed, soil, faeces and grass. it is hypothesized that differences in feeding and housing strategies of cows may influence the microbial quality of milk. this assumption was investigated through comparison of the aerobic spore-forming flora in milk from organic and conventional dairy farms. laboratory pasteurized milk samples from five conventional and five organic dairy farms, sampled in late summer ...200818406093
assessment of ccpa-mediated catabolite control of gene expression in bacillus cereus atcc 14579.the catabolite control protein ccpa is a transcriptional regulator conserved in many gram-positives, controlling the efficiency of glucose metabolism. here we studied the role of bacillus cereus atcc 14579 ccpa in regulation of metabolic pathways and expression of enterotoxin genes by comparative transcriptome analysis of the wild-type and a ccpa-deletion strain.200818416820
wst-1-based cell cytotoxicity assay as a substitute for mtt-based assay for rapid detection of toxigenic bacillus species using cho cell line.bacillus cereus continues to be one of the important foodborne pathogens due to its ability to produce various heat-labile and -stable toxins. several methods have been developed to assess the pathogenicity of the b. cereus strains; however, most of these take more than 2-3 days to provide confirmatory results. in this study we standardized a one-step cytotoxicity assay using wst-1 (4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2h-5-tetrazolio]-1,3-benzene disulfonate) and compared with the traditional ...200818417231
oleanane-type triterpenes from the flowers and roots of saussurea muliensis.six new oleanane-type triterpenes (1- 6), along with five known compounds, were isolated from the flowers and roots of saussurea muliensis. on the basis of spectroscopic methods, with special emphasis on 1d and 2d nmr techniques, the structures of the new compounds were characterized as 3beta,22alpha-dihydroxyolean-12-en-30-oic acid (1), 3alpha-(e)-caffeoyloxyolean-12-en-30-oic acid (2), 3alpha-(e)-coumaroyloxyolean-12-en-30-oic acid (3), 3alpha,22alpha-diacetoxy-20beta,21alpha,29-trihydroxy-30- ...200818419156
from soil to gut: bacillus cereus and its food poisoning toxins.bacillus cereus is widespread in nature and frequently isolated from soil and growing plants, but it is also well adapted for growth in the intestinal tract of insects and mammals. from these habitats it is easily spread to foods, where it may cause an emetic or a diarrhoeal type of food-associated illness that is becoming increasingly important in the industrialized world. the emetic disease is a food intoxication caused by cereulide, a small ring-formed dodecadepsipeptide. similar to the virul ...200818422617
apofnr binds as a monomer to promoters regulating the expression of enterotoxin genes of bacillus cereus.bacillus cereus fnr is a member of the crp/fnr (cyclic amp-binding protein/fumarate nitrate reduction regulatory protein) family of helix-turn-helix transcriptional regulators. it is essential for the expression of hbl and nhe enterotoxin genes independently of the oxygen tension in the environment. we studied aerobic fnr binding to target sites in promoters regulating the expression of enterotoxin genes. b. cereus fnr was overexpressed and purified as either a c-terminal his-tagged (fnr(his)) f ...200818424517
degradation of raw feather by a novel high molecular weight extracellular protease from newly isolated bacillus cereus dcuw.biotreatment of feather wastes and utilization of the degraded products in feed and foodstuffs has been a challenge. in the present study, we have demonstrated the degradation of feather waste by bacillus cereus dcuw strain isolated during a functional screening based microbial diversity study on east calcutta wetland area. a high molecular weight keratinolytic protease from feather degrading dcuw strain was purified and characterized. moreover, utilization of degraded products during feather hy ...200818427848
bacillus cereus endophthalmitis following intravitreous bevacizumab injection.the first case of bacillus cereus endophthalmitis following an intravitreous injection of bevacizumab is described. a 77-year-old man presented to a retina specialist with an active choroidal neovascularization related to age-related macular degeneration for which he received intravitreous bevacizumab (1.25 mg) and post-injection topical gatifloxacin. eight hours later, the patient woke up with excruciating pain and a decline in vision associated with nausea and vomiting. a vitreous biopsy was p ...200818435343
a small-scale, low-cost isolation system for the incubation and rearing of low bacterial load chicks as a model to study microbial-intestinal interactions.a small-scale, economical isolator system was adapted to hatch and raise chicks in a bacteria-free environment as a means to observe bacterial interactions with the intestinal mucosa during early development. the design and construction of flexible plastic isolators for incubation and brooding are described along with methodologies for preparation of eggs for entry into the isolators, incubation and hatching. two trials were conducted, the first in august 2005 and the second in march 2006. resul ...200818435876
n-acyl homoserine lactonase promotes prevention of erwinia virulence with zwittermicin a-producing strain bacillus cereus.zwittermicin a (zwa), a hybrid polyketide- peptide antibiotic, and n-acyl -homoserine-lactonase (ahl-lactonase), a kind of quorum-quenching enzyme, have the potential to prevent the virulence of erwinia carotovora, which is a major pathogen of soft rot. the purpose of this study was to combine the two agents in one host to improve their prevention efficacy. ahl-lactonase was over-expressed in the zwa-producing strain bacillus cereus and derivates were identified to create genetically modified (g ...200818438870
the bacillus cereus containing sub-branch most closely related to bacillus anthracis, have single amino acid substitutions in small acid-soluble proteins, while remaining sub-branches are more variable.hoffmaster et al. [hoffmaster ar, ravel j, rasko da, chapman gd, chute md, marston ck, et al. identification of anthrax toxin genes in bacillus cereus associated with illness resembling inhalation anthrax. proc natl acad sci u s a 2004;101:8449-54; hoffmaster ar, hill kk, gee je, marston ck, de bk, popovic t, et al. characterization of bacillus cereus isolates associated with fatal pneumonias: strains are closely related to bacillus anthracis and harbor b. anthracis virulence genes. j clin micro ...200818439962
[biosorption of ag+ by heavy metals hyperresistant bacillus cereus strain hq-1].a newly isolated bacillus cereus strain hq-1 was found to possess high capability to absorb silver ions. the study showed that the biosorption process could be described well by pseudo-second-order kinetic model and freundlich isotherm model. higher cell concentration was favorable to the biosorption. temperature's effect on the biosorption was not obvious. the oxygenous and nitrogenous functional groups on the cell wall played a very important role in the process of biosorption. microdeposits w ...200818441945
relationship between bacterial load, species virulence, and transfusion reaction with transfusion of bacterially contaminated platelets.bacterial contamination is currently the major infectious hazard of platelet transfusion, but associations between bacterial species and quantity and transfusion reactions have not been characterized.200818444858
loss of enzyme activity during turnover of the bacillus cereus beta-lactamase catalysed hydrolysis of beta-lactams due to loss of zinc ion.metallo-beta-lactamases are zinc-ion-dependent and are known to exist either as mononuclear or as dinuclear enzymes. the kinetics and mechanism of hydrolysis of the native zinc bacillus cereus metallo-beta-lactamase (bcii) have been investigated under pre-steady-state conditions at different phs and zinc-ion concentrations. biphasic kinetics are observed for the hydrolysis of cefuroxime and benzylpenicillin with submicromolar concentrations of enzyme and zinc. the initial burst of product format ...200818449576
the role of a purine-specific nucleoside hydrolase in spore germination of bacillus thuringiensis.a homologous gene (iunh) of a putative nucleoside hydrolase (nh), which had been identified from the exosporia of bacillus cereus and bacillus anthracis spores, was cloned from bacillus thuringiensis subsp. kurstaki. disruption of iunh did not affect the vegetative growth and sporulation of bacillus thuringiensis, but promoted both inosine- and adenosine-induced spore germination. the inosine- or adenosine-induced germination rate decreased when the wild-type iunh gene was overexpressed in bacil ...200818451042
the members of the bacillus cereus group are commonly present contaminants of fresh and heat-treated milk.to determine the level of milk contamination by bacillus cereus sensu lato, 44 samples were collected from a dairy farm and two independent dairies in northeastern poland. a total of 680 b. cereus sensu lato isolates were recovered. based on spore counts, their highest level in milk was found during the spring and summer months. although significant variations in chromosomal dna polymorphisms among b. cereus sensu lato isolates were noted based on repetitive element sequence polymorphism (rep-pc ...200818456114
identification of a non-pathogenic surrogate organism for chlorine dioxide (clo2) gas treatment.the identification of non-pathogenic surrogate microorganisms is beneficial for determining and validating the efficacy of antimicrobial treatments in food manufacturing environments. a surrogate organism was identified to aid in the decontamination process of fresh produce when treated with chlorine dioxide (clo(2)) gas. thirty-two known strains of pathogenic and non-pathogenic microorganisms and seven unknown microbial isolates from mushroom, tomatoes, and strawberries were evaluated. the prim ...200818456115
participation of oxygen in the bacterial transformation of 2,4,6-trinitrotoluene.the exposure of bacillus cereus zs18 cell suspensions to 2,4,6-trinitrotoluene (tnt) in the absence of other oxidizable substrates increases oxygen uptake, exceeding the basal level of respiration of the bacterium 1.5- and 2-fold with 50 and 100 mg/liter of tnt, respectively. the interaction of both living and to less extent dead bacterial cells with tnt results in the accumulation of superoxide anion (o2*-) in the extracellular medium, which was revealed by the epr spectroscopy. the accumulatio ...200818457577
petrobactin is produced by both pathogenic and non-pathogenic isolates of the bacillus cereus group of bacteria.petrobactin is the primary siderophore synthesized by bacillus anthracis str sterne and is required for virulence of this organism in a mouse model. the siderophore's biosynthetic machinery was recently defined and gene homologues of this operon exist in several other bacillus strains known to be mammalian pathogens, but are absent in several known to be harmless such as b. subtilis and b. lichenformis. thus, a common hypothesis regarding siderophore production in bacillus species is that petrob ...200818459058
effects of bacillus cereus var. toyoi as probiotic feed supplement on intestinal transport and barrier function in piglets.the objective of the study was to assess the effects of feed supplementation with the probiotic bacillus cereus var. toyoi on transport and barrier properties of pig jejunum. sows and their respective piglets were randomly assigned to two feeding groups: a control group and a probiotic group in which the standard diet was supplemented with bacillus cereus var. toyoi. at the age of 14, 28, 35 and 56 days, 5 piglets per subgroup were killed and tissue samples from the mid jejunum were mounted in c ...200818459534
biosynthesis of enantiopure (s)-3-hydroxybutyric acid in metabolically engineered escherichia coli.a biosynthetic pathway for the production of (s)-3-hydroxybutyric acid (s3hb) from glucose was established in recombinant escherichia coli by introducing the beta-ketothiolase gene from ralstonia eutropha h16, the (s)-3-hydroxybutyryl-coa dehydrogenase gene from r. eutropha h16, or clostridium acetobutylicum atcc824, and the 3-hydroxyisobutyryl-coa hydrolase gene from bacillus cereus atcc14579. artificial operon consisting of these genes was constructed and was expressed in e. coli bl21 (de3) co ...200818461320
a structure-activity study of antibacterial diterpenoids.an analysis of the antibacterial activities of 15 terpenoids, eleven of which were previously described by us and four were extracted from the literature, suggested two structural requirements for activity of these and related compounds: a hydrophobic moiety,consisting of a substituted decalin skeleton, and a hydrophilic region possessing one hydrogen-bond-donor group. these structural requirements are responsible for an optimal insertion of these and related compounds into cell membranes, as su ...200818463590
accurate localization of the integration sites of two genomic islands at single-nucleotide resolution in the genome of bacillus cereus atcc 10987.we have identified two genomic islands, that is, bcegi-1 and bcegi-2, in the genome of bacillus cereus atcc 10987, based on comparative analysis with bacillus cereus atcc 14579. furthermore, by using the cumulative gc profile and performing homology searches between the two genomes, the integration sites of the two genomic islands were determined at single-nucleotide resolution. bcegi-1 is integrated between 159705 bp and 198000 bp, whereas bcegi-2 is integrated between the end of orf bce4594 an ...200818464912
absolute configuration and antimicrobial activity of acylhomoserine lactones.(s)-n-heptanoylhomoserine lactone is an uncommon acyl odd-chain natural product employed by many gram-negative bacteria as a signaling substance in chemical communication mechanisms known as quorum sensing. the absolute configuration determination of the metabolite produced by the phytopathogen pantoea ananatis serrano is reported herein. as with all other substances of this class, the lactone moiety possesses s configuration, corroborating the hypothesis that it shares the same biosynthetic pat ...200818465897
synergistic interactions between chitinase chicw and fungicides against plant fungal pathogens.antifungal activity of chicw and synergistic interactions between chicw with fungicides were investigated. conidial germinations of phytopathogenic fungi, alternaria brassicicola, botrytis elliptica, and colletotrichum gloeoporioides, were inhibited by chicw but a. longipes was not. in addition, chicw showed synergistic effect with fungicides switch (cyprodinil+fludioxonil) and tebuconazole to inhibit fungal conidial germinations. the level of synergism of chicw with tebuconazole was higher than ...200818467877
enterotoxins and emetic toxins production by bacillus cereus and other species of bacillus isolated from soumbala and bikalga, african alkaline fermented food condiments.the ability of various species of bacillus from fermented seeds of parkia biglobosa known as african locust bean (soumbala) and fermented seeds of hibiscus sabdariffa (bikalga) was investigated. the study included screening of the isolates by haemolysis on blood agar, detection of toxins in broth and during the fermentation of african locust bean using the bacillus cereus enterotoxin reverse passive latex agglutination test kit (bcet-rpla) and the bacillus diarrhoeal enterotoxin visual immunoass ...200818474404
preparation and use of media for protease-producing bacterial strains based on by-products from cuttlefish (sepia officinalis) and wastewaters from marine-products processing factories.cuttlefish powder (cfp) from sepia officinalis by-products was prepared and tested as a fermentation substrate for microbial growth and protease production by several species of bacteria: bacillus licheniformis, bacillus subtilis, pseudomonas aeruginosa, bacillus cereus bg1, and vibrio parahaemolyticus. all microorganisms studied grew well and produced protease activity when cultivated in medium containing only cfp indicating that the strains can obtain their carbon and nitrogen source requireme ...200816962303
the use of clinical profiles in the investigation of foodborne outbreaks in restaurants: united states, 1982-1997.improving the efficiency of outbreak investigation in restaurants is critical to reducing outbreak-associated illness and improving prevention strategies. because clinical characteristics of outbreaks are usually available before results of laboratory testing, we examined their use for determining contributing factors in outbreaks caused by restaurants. all confirmed foodborne outbreaks reported to the centers for disease control and prevention (cdc) from 1982 to 1997 were reviewed. clinical pro ...200817335632
extending the bacillus cereus group genomics to putative food-borne pathogens of different toxicity.the bacillus cereus group represents sporulating soil bacteria containing pathogenic strains which may cause diarrheic or emetic food poisoning outbreaks. multiple locus sequence typing revealed a presence in natural samples of these bacteria of about 30 clonal complexes. application of genomic methods to this group was however biased due to the major interest for representatives closely related to bacillus anthracis. albeit the most important food-borne pathogens were not yet defined, existing ...200817434157
new triazole and triazolothiadiazine derivatives as possible antimicrobial agents.triazole and triazoles fused with six-membered ring systems are found to possess diverse applications in the fields of medicine, agriculture and industry. the new 1,2,4-triazole and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazine derivatives were synthesized as novel antimicrobial agents. the reaction of 1h-indol-3-acetic acid with thiocarbohydrazide gave the 4-amino-3-mercapto-5-[(1h-indol-3-yl)methyl]-4h-1,2,4-triazole. the reaction of triazole with arylaldehydes in ethanol gave the 4-arylideneamino-3 ...200817499887
crystal structure of the bczbp, a zinc-binding protein from bacillus cereus.bacillus cereus is an opportunistic pathogenic bacterium closely related to bacillus anthracis, the causative agent of anthrax in mammals. a significant portion of the b. cereus chromosomal genes are common to b. anthracis, including genes which in b. anthracis code for putative virulence and surface proteins. b. cereus thus provides a convenient model organism for studying proteins potentially associated with the pathogenicity of the highly infectious b. anthracis. the zinc-binding protein of b ...200717501983
simultaneous removal of chlorothalonil and nitrate by bacillus cereus strain ns1.elevated no3- and chlorothalonil (ctn) have been found in production nursery recycling ponds. bacillus cereus strain ns1 isolated from nursery recycling pond sediment was assessed for its ability to reduce no3- and degrade ctn in a mineral medium. the results showed that the efficiency of no3- reduction and ctn degradation by b. cereus strain ns1 were related to the nature of organic carbon sources added to the medium. in the medium amended with 100 mg/l yeast extract, 86% of no3- (100 mg/l) and ...200717509667
food poisoning due to jimson weed mimicking bacillus cereus food intoxication in austria, 2006. 200717512772
toxin production in a rare and genetically remote cluster of strains of the bacillus cereus group.three enterotoxins are implicated in diarrhoeal food poisoning due to bacillus cereus: haemolysin bl (hbl), non-haemolytic enterotoxin (nhe), and cytotoxin k (cytk). toxin gene profiling and assays for detection of toxin-producing stains have been used in attempts to evaluate the enterotoxic potential of b. cereus group strains. b. cereus strain nvh 391/98, isolated from a case of fatal enteritis, was genetically remote from other b. cereus group strains. this strain lacked the genes encoding hb ...200717517121
bacillus cereus spores during housing of dairy cows: factors affecting contamination of raw milk.the contamination of raw milk with bacillus cereus spores was studied during the indoor confinement of dairy cattle. the occurrence of spores in fresh and used bedding material, air samples, feed, feces, and the rinse water from milking equipment was compared with the spore level in bulk tank milk on 2 farms, one of which had 2 different housing systems. a less extensive study was carried out on an additional 5 farms. high spore concentrations of >100 spores/l in the raw milk were found on 4 of ...200717517714
two distinct manganese-containing superoxide dismutase genes in bacillus cereus: their physiological characterizations and roles in surviving in wheat rhizosphere.rhizosphere inhabitants interact intricately with plant host. bacillus cereus 905 isolated from wheat rhizosphere colonized wheat rhizosphere with large population size. in this work, the role of superoxide dismutases (sods) of b. cereus 905 in surviving in wheat rhizosphere was analyzed. two genes, soda-1 and soda-2 encoding two distinct manganese sods (mnsods), were isolated from the bacterium. the amino acid sequence similarity between the two peptides is 58.43%. through homologous recombinat ...200717521361
[bacillus cereus enterotoxins].data about bacillus cereus different enterotoxins including hemolysin (hbl), nonhemolytic enterotoxin (nhe), enterotoxin (t), and emesis-inducing thermostable enterotoxin (ete) are summarized in the article. information about synthesis of different diarrhea-inducing and emesis-inducing enterotoxins, methods of their purification, structure, functions, and mechanisms of action are presented. commercial kits for identification of b. cereus enterotoxins causing food-associated diarrhea are listed.200717523492
phenotypic and functional characterization of bacillus anthracis biofilms.biofilms, communities of micro-organisms attached to a surface, are responsible for many chronic diseases and are often associated with environmental reservoirs or lifestyles. bacillus anthracis is a gram-positive, endospore-forming bacterium and is the aetiological agent of pulmonary, gastrointestinal and cutaneous anthrax. anthrax infections are part of the natural lifecycle of many ruminants in north america, including cattle and bison, and b. anthracis is thought to be a central part of this ...200717526827
large-scale production and efficient recovery of phb with desirable material properties, from the newly characterised bacillus cereus spv.a newly characterised bacillus strain, bacillus cereus spv was found to produce phb at a concentration of 38% of its dry cell weight in shaken flask cultures, using glucose as the main carbon source. polymer production was then scaled up to 20 l batch fermentations where 29% dry cell weight of phb was obtained within 48 h. following this, a simple glucose feeding strategy was developed and the cells accumulated 38% dry cell weight of phb, an increase in the overall volumetric yield by 31% compar ...200717532079
differentiation and characterization by molecular techniques of bacillus cereus group isolates from poto poto and dégué, two traditional cereal-based fermented foods of burkina faso and republic of congo.poto poto (a maize sourdough) and dégué (a pearl millet-based food) are two traditional african fermented foods. the molecular biology of toxigenic and pathogenic bacteria found in those foods is largely unknown. the purpose of this study was to study the phylogenetic relatedness and toxigenic potential of 26 bacillus cereus group isolates from these traditional fermented foods. the relatedness of the isolates was evaluated with repetitive element sequence-based pcr (rep-pcr) and 16s rdna sequen ...200717536675
a novel antibiotic bone assay by liquid chromatography/tandem mass spectrometry for quantitation of tigecycline in rat bone.tigecycline (tygacil) is a first-in-class, broad spectrum antibiotic with activity against antibiotic-resistant organisms. in rats and humans, tigecycline readily distributes to bone tissue but its accuracy of quantitation via liquid chromatography/mass spectrometry (lc/ms/ms) is hindered by a low extraction recovery when using a conventional plasma extraction method. to overcome this issue, we have identified an effective extraction solvent for quantitation of tigecycline in rat bone. the curre ...200717537611
genomic diversity and relationship of bacillus thuringiensis and bacillus cereus by multi-rep-pcr fingerprinting.the genomic diversity and relationship among 56 bacillus thuringiensis and bacillus cereus type strains were investigated by multi-rep-pcr fingerprinting consisting of three pcr reactions targeting the enterobacterial eric1 and eric2 and the streptococcal boxa1r consensus sequences. a total of 113 polymorphic bands were generated in the rep-pcr profiles that allowed tracing of a single dendrogram with three major groups. bacillus cereus strains clustered together in the a and b groups. most of t ...200717538643
mycorrhizal fungi and ectomycorrhiza associated bacteria isolated from an industrial desert soil protect pine seedlings against cd(ii) impact.effects of mycorrhization with amanita rubescens or hebeloma sinapizans and dual inoculation with the fungi and ectomycorrhiza associated bacteria (emab) pseudomonas putida or bacillus cereus on seedling growth and accumulation of cd(ii) in pinus sylvestris were studied. both fungal and bacterial species were isolated from roots of pines growing in an industrial area polluted with high concentrations of heavy metals. during mycorrhization, a. rubescens colonized higher number of pine seedlings t ...200717541824
antibacterial activity of extract, fractions and four compounds extracted from piper solmsianum c. dc. var. solmsianum (piperaceae).piper solmsianum c. dc. var. solmsianum (piperaceae) is a shrub commonly found in areas with wet tropical soils. other piper species have been used in folk medicine as antitumoral and antiseptic agents. we studied the crude methanolic extract, some organic fractions and compounds isolated from this plant for possible antimicrobial activity against gram-positive and gram-negative bacteria. the bioautographic assays disclosed three inhibition zones. the minimal inhibitory concentration (mic) and m ...200717542481
synthesis, characterization and antimicrobial activity of new aliphatic sulfonamide.a series of novel aliphatic sulfonamide derivatives (1-7) were synthesized and characterized by elemental analyses, ft-ir, (1)h nmr, (13)c nmr and lc-ms techniques. all the synthesized compounds were evaluated in vitro as antimicrobial agents against representative strains of gram-positive (staphylococcus aureus atcc 25953, bacillus cereus atcc 6633 and listeria monocytogenes atcc li6 (isolate), gram-negative bacteria (escherichia coli atcc 11230) and antifungal agent against candida albicans (c ...200717544281
the contribution of gc1qr/p33 in infection and inflammation.human gc1qr/p33 is a multi-compartmental and multi-functional cellular protein expressed on a wide range of tissues and cell types including lymphocytes, endothelial cells, dendritic cells, and platelets. although originally isolated as a receptor for c1q by virtue of its affinity (k(d)=15-50 nm), and specificity for the globular heads of this molecule, a large body of evidence has now been accumulated which shows that in addition to c1q, gc1qr can serve as a receptor for diverse proinflammatory ...200717544818
Refresh
firstprev
...31323334353637383940...
nextlast
Displaying items 3001 - 3100 of 8187