Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| radiotherapy in leukemia and lymphoma of children. | radiotherapy is important in the treatment of leukemia and lymphoma of children. in acute lymphocytic leukemia administration of cranial irradiation early during chemotherapy-induced remission prevents initial meningeal relapse. when cranial irradiation is combined with a 3-year course of multiple drug systemic chemotherapy approximately one-half of the children remain in complete remission for 5 years or more and are at little risk of relapse. preventive cranial irradiation is effective in chil ... | 1983 | 264798 |
| laws, regulations, and policies. | 1983 | 347936 | |
| health manpower in new zealand. the swinging pendulum. | 1983 | 272578 | |
| ventricular fibrillation during acute rejection after heart transplantation. | the case of a 46-year-old patient who underwent orthotopic heart transplantation for treatment of end-stage heart failure as a result of ischemic heart disease is reported. four months after transplantation a grade ii rejection episode was complicated by ventricular fibrillation. lidocaine and procainamide intravenously did not effectively prevent recurrence. an increase of antirejection therapy in combination with flecainide acetate effectively prevented further episodes of ventricular fibrilla ... | 1982 | 1498146 |
| are our dental laws adequate? | 1982 | 351168 | |
| [dyslipidemia and accelerated atherosclerosis in chronic uremia: a probably decreasing pathology, due to nutritional studies and better dietary guidelines]. | 1982 | 216602 | |
| acquisition of trimethoprim resistance in epidemic strain of shigella dysenteriae type 1 from zaire. | 1982 | 6122794 | |
| [obtaining dysentery and salmonellosis diagnostica for the coagglutination reaction in lyophilized form and the elaboration of a rapid system]. | 1982 | 6182376 | |
| bacterial agents in acute diarrhea. | 1982 | 6191462 | |
| the nucleotide sequence coding for major outer membrane protein ompa of shigella dysenteriae. | the nucleotide sequence of the ompa gene from shigella dysenteriae has been determined and the amino acid sequence of the pro-ompa protein predicted. sequence comparison between the ompa genes of s.dysenteriae and escherichia coli showed that features such as mrna secondary structure and codon usage, as well as polypeptide function, have been conserved during evolution. the pro-ompa protein of s.dysenteriae consists of 351 residues, as opposed to the 346 of the e.coli protein and also shows seve ... | 1982 | 6283478 |
| increase in drug resistance among shigella dysenteriae, sh flexneri, and sh boydii. | 1982 | 6803969 | |
| [antigens of shigella dysenteriae serovars 3-7. iv. immunochemical study of the exotoxin]. | the exotoxins of sh. dysenteriae, serovars 3 and 7, possess antigenic and serological properties and are characterized by the heterogeneous antigenic structure which distinctly differs from the structure of o-antigen in its immunochemical properties. these exotoxins consist of thermolabile and thermostable components. the thermolabile exotoxin fraction is a lethal toxin. the thermostable exotoxin fraction, obtained from the cultures of sh. dysenteriae in the s-form, corresponds to o-antigen and ... | 1982 | 6808792 |
| cloning and expression in escherichia coli k-12 of the genes for major outer membrane protein ompa from shigella dysenteriae, enterobacter aerogenes, and serratia marcescens. | the outer membranes of many gram-negative bacteria contain a major heat-modifiable protein which shows serological cross-reactivity with the ompa protein of escherichia coli k-12. using the cloned gene for the e. coli k12 protein as a dna-dna hybridization probe, we were able to identify the corresponding genes from shigella dysenteriae. enterobacter aerogenes, and serratia marcescens. these were cloned in a phage lambda vector, and their expression in e. coli k-12 was studied. all three ompa pr ... | 1982 | 7033204 |
| immunochemical and cytotoxic activities of shigella dysenteriae 1 (shiga) and shiga-like toxins. | toxins in culture supernatants and bacterial lysates of s. dysenteriae 1 and s. flexneri were quantitated by a cytotoxicity assay and a newly developed radioimmunoassay. cytotoxin titers paralleled toxin antigen levels. thus, variations in cytotoxicity among shigellae probably reflect differences in toxin yield rather than specific activity (cytotoxicity per microgram of toxin antigen). | 1982 | 7040247 |
| fever, antipyretics and serum iron levels in rabbits. | the intracerebroventricular (i.c.v.) injection of bacterial endotoxin (shigella dysenteriae) produces a rise in deep-body temperature in rabbits. the increase in body temperature was partially inhibited by polymyxin b (p), and completely suppressed by ketoprofen (k). the systemic injection of bacterial endotoxins (shigella dysenteriae or salmonella typhosa) elicited an elevation of body temperature in rabbits which was partially blocked by polymyxin b and completely antagonized by ketoprofen. se ... | 1982 | 6983446 |
| production of shigella dysenteriae type 1-like cytotoxin by escherichia coli. | strains of escherichia coli previously implicated or proven to be causes of diarrhea were examined for production of a toxin similar to that of shigella dysenteriae type 1 (shiga). organisms grown in an iron-depleted broth were lysed by pressure disruption followed by ultracentrifugation. saline-dialyzed extracts were tested for cytotoxic effects on hela cells that were neutralizable with antiserum to shiga toxin. among the 13 e. coli strains so analyzed, 11 made a shiga-like cytotoxin in levels ... | 1982 | 6754826 |
| [bacillary dysentery - 1980]. | 1982 | 6755564 | |
| [use of coagglutination for serotyping shigella dysenteriae and shigella boydii]. | the coagglutination test was used to identify shigella boydii and shigella dysenteriae. a trial was carried out with 13 native rabbit antisera to s. boydii and 10 antisera to s. dysenteriae, as well as with coagglutinating reagents prepared from these antisera. the use of coagglutinating reagents was shown to ensure the complete specificity of the results, to prevent the adsorption of diagnostic antisera and to decrease their consumption 50 times. the importance of the coagglutination test for t ... | 1982 | 6760638 |
| bacterial adhesiveness and invasiveness in cell culture monolayer. 2. in vitro invasiveness of 45 strains belonging to the family enterobacteriaceae. | the invasive potential of 45 presumptive enteropathogenic and non-enteropathogenic bacterial strains belonging to the family enterobacteriaceae have been tested using the serény test and hep-2 cell monolayers examined by a combined light optical method. all the presumptive enteropathogenic strains of shigella dysenteriae, s. boydii, s. flexneri, s. sonnei and salmonella typhimurium showed in vitro invasiveness in the hep-2 cell culture test. fourteen presumptive non-enteropathogenic strains of e ... | 1982 | 6762798 |
| isolation of the shigella genus bacteria from the beach sand and water of the bay of gdańsk. | 1982 | 6764618 | |
| [anti-shigella dysenteriae 1 antibodies in the mexican population. their possible relation to the central american outbreaks of 1968-70]. | 1982 | 6765039 | |
| purification of a lethal toxin produced by shigella dysenteriae. | a lethal toxin was purified from the culture supernatant of shigella dysenteriae 1. the purification procedure utilized ammonium sulfate fractionation, column chromatography on deae-cellulose, cm-cellulose, hydroxylapatite and gel filtration on sephadex g-200. about a 4760-fold purification was achieved, with a yield of 2.7%. the purified lethal toxin appeared homogeneous on polyacrylamide gel disc electrophoresis. the ld50 of the purified lethal toxin in mice following i.p. injection was about ... | 1982 | 7043787 |
| expression in escherichia coli k12 of the cloned genes for a major outer membrane protein (ompa protein) from shigella dysenteriae, enterobacter aerogenes and serratia marcescens. | 1982 | 7044211 | |
| structural studies on a polysaccharide from shigella dysenteriae type 7. | the polysaccharide obtained from the o-somatic antigen of shigella dysenteriae type 7 (strain nctc 519/66) contains d-glucose, d-galactose, and 2-acetamido-2-deoxy-d-glucose in the mole ratios of 2:1-1. from the results of methylation, periodate oxidation, graded hydrolysis, and deamination studies, the structure assigned to the repeating unit of the polysaccharide is as follows, (formula: see text) oxidation studies with chromium trioxide revealed the nature of the anomeric linkages of some of ... | 1982 | 7046934 |
| purification and biological characterization of shiga toxin from shigella dysenteriae 1. | shiga toxin has been purified in milligram quantities to near homogeneity from cell lysates of shigella dysenteriae 1 strain 3818-0. purification involved an initial ultracentrifugation, ammonium sulfate fractionation, chromatography on deae-cellulose and carboxymethyl cellulose, gel filtration, and preparative isoelectric focusing in sucrose gradients. the purified toxin was resolved by discontinuous polyacrylamide gel electrophoresis into a major cytotoxic protein band and a closely migrating, ... | 1982 | 7047403 |
| enumeration and identification of pathogenic bacteria from sewage in kuwait. | mycobacterium spp. was isolated and enumerated in all sewage samples at different stages of the sewage treatment. aeromonas hydrophila, salmonella spp., shigella dysenteriae and others were isolated from both treated and untreated sewage. moreover, the serological identification of salmonella spp. was also done, using antisera specific to their antigenic structures. counts of bacteria in various sewage sludges and effluents tested showed the efficiency of the activated sludge process in reducing ... | 1982 | 7168261 |
| [antimicrobial activity of chlorine-substituted 4-alkyl- and arylphenols]. | the results of the study on the antimicrobial activity of 12 chlorine-substituted 4-alkyl- and arylphenols against staphylococcus, streptococcus, e. coli, salmonella typhosa, salmonella typhimurium, shigella dysenteriae, proteus, klebsiella rhinoscleromatis, candida, trichophyton gypseum and microsporum lanosum are presented. it was found that introduction of the alkyl substitute to position 4 of orthochlorphenol increased the activity of the substances against the majority of test microbes. the ... | 1981 | 7271258 |
| measurement of hypozincaemia in mice: a sensitive test for detection of pyrogens. | 1. the effect of bacterial pyrogens on plasma zinc concentration in mice was studied as a method of bioassay for these substances. 2. a dose-related depression of plasma zinc concentrations was observed 4 h after intravenous injection of doses of 0.05-500 ng of purified endotoxins of salmonella abortus equi, shigella dysenteriae and escherichia coli. responses were dose-dependent and reproducible for each endotoxin in five strains of mice. 3. tolerance to endotoxin could be induced in mice by in ... | 1981 | 7285495 |
| increase in drug resistance among shigella dysenteriae, sh flexneri, and sh boydii. | two thousand three hundred and seventy strains of shigella dysenteriae, sh flexneri, and sh boydii isolated in england and wales from 1974 to 1978 were tested for resistance to 12 antimicrobial drugs. eighty per cent of strains were resistant to one or more drugs, with sulphonamide resistance occurring most frequently. resistance to streptomycin, tetracycline, ampicillin, and chloramphenicol increased during the period, as did the incidence of multiple resistance. most infections due to sh dysen ... | 1981 | 6790085 |
| immune response to parental and rough mutant strains of salmonella minnesota. | specificity of immune response to smooth and rough mutant strains of salmonella minnesota was investigated. immunization of mice with rd and re rough mutants resulted in formation of bactericidal plaque-forming cells directed against the lipopolysaccharide structure of both the mutants and the parental smooth strain. these antibody plaques, however, were not bactericidal for smooth strains of other gram-negative species, i.e., escherichia coli, salmonella typhosa, klebsiella pneumoniae, shigella ... | 1981 | 6793518 |
| behavioural and body temperature effects of meningococcal lipopolysaccharide after intraventricular injection in adult fowls gallus domesticus. | the effects of the meningococcal lipopolysaccharide (lps), given into the ii cerebral ventricle of adult fowls, were studied on behaviour and body temperature. immediately after the administration a marked and dose- dependent behavioural sedation or sleep lasting over 2 hours or more according to the dose was observed. the body temperature effects of lps were biphasic, i.e. and immediate initial phase of hypothermia lasting about 100 min, followed by a longer-lasting fever response. a pretreatme ... | 1981 | 6800001 |
| [etiological factors in bacillary dysentery in poland 1965-1979]. | 1981 | 7041196 | |
| [shigellosis in pediatric wards]. | 1981 | 7042492 | |
| enterotoxigenic bacteria in food and water from an ethiopian community. | food and water samples from an ethiopian community were screened for the presence of enterotoxin-producing bacteria. using the chinese hamster ovary cell assay, 40 of 213 isolates (18.8%) produced heat-labile (lt) enterotoxin. these lt-producing isolates comprised 33 of 177 (18.6%) strains from 24 of 68 food samples (35.3%) and 7 of 36 (19.4%) isolates of 4 of 17 water samples (23.5%). one lt-producing strain each of salmonella emek and of shigella dysenteriae was found. three pseudomonads, all ... | 1981 | 7016032 |
| salmonella and shigella surveillance in hungary, 1972-1976. ii. shigella surveillance. | shigellae were isolated from 32 399 persons in the bacteriological laboratories of the public health stations between 1972-1976. the number of isolations ranged between 5325 and 8237 yearly. as s. dysenteriae and s. boydii serotypes occurred only in about 1.5% of all isolations, the epidemiological situation was determined by the incidence of s. flexneri and s. sonnei. except in 1973, s. sonnei constituted the majority in every year. s. sonnei predominance, observed first in the western regions ... | 1981 | 7020354 |
| subunit structure of shigella cytotoxin. | shigella cytotoxin was purified from the culture medium of shigella shigae 60 r and from the bacterial pellet by an extensive purification scheme involving chromatography on cibachron blue f3ga, chitin, and deae-cellulose columns, sucrose gradient centrifugation, and finally polyacrylamide gel electrophoresis under nondenaturing conditions. in sodium dodecyl sulfate polyacrylamide gels, purified toxin showed two bands, a heavy one with the molecular weight of 30,500 (a chain), and a broad band m ... | 1981 | 7021550 |
| [serologic affinity and specificity of action of pseudotuberculosis and coli-dysentery phages]. | the study of serological properties, specificity and the range of action has revealed affinity between y. pseudotuberculosis phages (pst, 3m, kotlyarova, 2344, 2391), some coliphages (t2, t3, t4) and sh. dysenteriae phage (dd iv). the existence of serovar iii of y. pseudotuberculosis phages has been established; to this serovar phage pst belongs. newly isolated 2344 and 2391 belong to serovar i. the problem of the existence of y. pseudotuberculosis phages as an independent group is discussed. | 1981 | 7023155 |
| [diagnosis of grigor'ev-shiga dysentery]. | the data on the relative significance and composition of sh. dysenteriae serovars isolated in some regions of the ussr in 1975-1979 are presented. special tests revealed that endo agar was the best medium, while ploskirev's agar was the worst medium for growing sh. dysenteriae 1 (the museum strain and the newly isolated strain from bangladesh). the testing of agar with eosine-methylene blue yielded moderate results in respect of the growth of the museum strain; as to the growth of the strain fro ... | 1981 | 7025526 |
| association of cockroaches with an outbreak of dysentery. | 1981 | 7029807 | |
| [antigens of shigella dysenteriae serovars 3-7. iii. chemical composition, toxic and physicochemical properties of exotoxins]. | the exotoxins of shigella dysenteriae, serovars 3-7, were isolated. these exotoxins were found to differ from o-antigens in their chemical composition and resistance to heating, drying and the action of chemical substances. the toxicity of exotoxin was determined by its thermolabile component. exotoxin formation varied in different strains. the preparations obtained from the cultures in the s-form, isolated from patients with severe toxic forms of the infectious process, possessed the highest to ... | 1981 | 7029981 |
| the cytotoxic activity of shigella toxin. evidence for catalytic inactivation of the 60 s ribosomal subunit. | the cytotoxic test system for shigella shigae toxin was improved and used to study the stability of the toxin to various ph values, temperature, and chemicals. inhibition of protein synthesis is the first demonstrable effect in cells treated with shigella toxin. this inhibition appears to be at the level of peptide chain elongation. an inhibition effect on cell-free protein synthesis is exhibited by toxin pretreated first with trypsin and then with dithiothreitol and 8 m urea or 1% sodium dodecy ... | 1981 | 6894922 |
| in vitro antibacterial activity of fluorinated analogs of chloramphenicol and thiamphenicol. | we evaluated the in vitro antimicrobial activity of sch 24893, sch 25298, and sch 25393, three novel analogs of chloramphenicol and thiamphenicol. all of the analogs had minimal inhibitory concentrations of less than or equal to 10 micrograms/ml for 18 chloramphenicol-thiamphenicol-resistant strains of shigella dysenteriae and 21 strains of resistant salmonella typhi. the analogs were also more active than were chloramphenicol and thiamphenicol against chloramphenicol-resistant enteric bacteria, ... | 1981 | 6957162 |
| protein synthesis in hela or henle 407 cells infected with shigella dysenteriae 1, shigella flexneri 2a, or salmonella typhimurium w118. | the incorporation of [14c]leucine into protein was studied in two mammalian cell lines which had been infected with strains of shigella dysenteriae 1, shigella flexneri 2a, or salmonella typhimurium w118. these cell lines differed in susceptibility to the effects of exogenously applied shiga cytotoxin. all invasive shigella strains (which synthesize this toxin to a greater or lesser degree) were found to inhibit protein synthesis in both cell lines with equal efficiency. leucine accumulation con ... | 1981 | 7012026 |
| susceptibility of shigellae to mecillinam, nalidixic acid, trimethoprim, and five other antimicrobial agents. | a total of 199 strains of shigella (1 shigella dysenteriae, 15 s. boydii, 47 s. flexneri, and 136 s. sonnei) isolated in malmö, sweden, within a 3-year period (1977 through january 1980) were tested with the agar plate dilution method for susceptibility to commonly used and newer antimicrobial agents. mecillinam, nalidixic acid, and trimethoprim had the best in vitro activity. s. flexneri dominated among strains resistant to three or more antimicrobial agents and were less susceptible to ampicil ... | 1981 | 6289727 |
| multiple copies of iso-insertion sequences of is1 in shigella dysenteriae chromosome. | 1981 | 6265806 | |
| dissimilar effects on body temperature in the cat produced by guanosine 3',5'-monophosphate, acetylcholine and bacterial endotoxin. | 1 guanosine 3',5'-monophosphate (cyclic gmp) and n2-2'-o-dibutyryl guanosine 3',5'-monophosphate (db cyclic gmp) have been injected into the third cerebral ventricle (i.c.v.) of the unanaesthetized cat and the effects of rectal temperature and on behavioural and autonomic activities observed and compared with those of acetylcholine and physostigmine. 2 acetylcholine (100 nmol) and physostigmine (100 nmol) injected together i.c.v. produced a rise in body temperature in cats at an environmental te ... | 1981 | 6274463 |
| plasmid characterisation in the investigation of an epidemic caused by multiply resistant shigella dysenteriae type 1 in central africa. | a strain of shigella dysenteriae type 1 resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides, and tetracyclines has caused an epidemic of shiga dysentery in northeast zaire. since november 1979, it has caused many deaths in an extensive area which now includes neighbouring rwanda. the strain carries a resistance plasmid of compatibility group x, indistinguishable from the plasmid previously found in strains from somalia. this contrasts with multiply resistant strains of sh. dyst ... | 1981 | 6118525 |
| the respiratory system. 2. chronic bronchitis and emphysema. | 1981 | 243850 | |
| toluene diisocyanate (tdi) pulmonary disease: immunologic and inhalation challenge studies. | clinical and serologic effects of tdi exposure were studied in 112 occupationally exposed plant workers. sera were obtained before and after commencement of tdi production. all subjects were skin-tested with common inhalant allergens and a tdi-hsa conjugate. total eosinophil counts, immunoglobulin quantitations, and specific antibody assays by pca, p-k, and radioimmunoassay were performed. clinically "sensitive" individuals were tested by provocative inhalation challenge with from 0.005 ppm to t ... | 1981 | 181412 |
| structural equation modeling in clinical assessment research with children. | the use of structural equation modeling has gained increased interest in recent years in the social and behavioral sciences. this article reviews the basic tenets of structural modeling in relation to issues in research and practice involving clinical assessment and compares this approach with more traditional psychometric approaches to the validation of assessment instruments with children. arguments for and against the inclusion of nonexperimental variables in causal studies aimed at establish ... | 1981 | 2071721 |
| integrating general medicine and rheumatology training in the outpatient setting: a practice model. | the authors describe a primary care-based educational and practice model that integrates general medicine resident education in outpatient rheumatology with specialty fellowship training. compared with the use of traditional specialty clinics, the model provides better access and service to patients and more appropriate training for residents. revenues from clinical service delivered by faculty-supervised residents and fellows support 80% of the operating costs and educational activities of the ... | 1981 | 1506951 |
| effect of sodium fluoride rinsing on dental plaque accumulation. | 1. daily rinsing with water does not prevent plaque accumulation and leads to increased levels of gingival inflammation. 2. toothbrushing or mouth rinsing with sodium fluoride alone decreases plaque accumulation and improves gingival health. 3. the combined method (toothbrushing and rinsing with sodium fluoride) is the most effective. confirmation of the above results and conclusions requires additional experiments carried out over a longer period of time. | 1980 | 273591 |
| [urinary tract infections in childhood (author's transl)]. | the clinical symptoms of urinary tract infections (uti) are only rarely an indication of the presence of the disease in childhood. of decisive importance for the detection of uti is an appropriate investigation to determine whether there is significant bacteriuria. since in a significant proportion of cases of uti in children there is underlying congenital anomaly or functional change in the urinary tract with stasis, and since surgical means of treatment are available today, diagnosis, i.e. at ... | 1980 | 551080 |
| time--a neglected aspect of psychiatric treatments. | this review attempts to deal with the complex issues involved in the time to heal, with special reference to psychological processes. the questions of convalescence and relapse in organic medicine are explored and extrapolated to psychiatric processes. the concept of a latency period of change in treatment outcome is discussed with reference to both less complicated reactive states as well as highly charged neurotic processes. the problems of recognizing slow but perceptible change and separatin ... | 1980 | 283799 |
| [stereometry: study of volume changes of wax and self-curing acrylic resin models by means of cartesian coordinates]. | 1980 | 293819 | |
| [interest of gamma-glutamyltransferase in "enterobacteriaceae" (author's transl)]. | gamma-glutamyltransferase (gammagt) could be detected in 86,6% of 3,027 strains of enterobacteriaceae, by the use of gamma-l-glutamin-p-nitranilide acid for substrate. the following species produced gamma gt: citrobacter freundii, levinea malonatica, l. amalonatica, klebsiella pneumoniae, k. oxytoca, k. ozaenae, enterobacter aerogenes, e. cloacae, e. agglomerans, e. gergoviae, k. ozaenae, enterobacter aerogenes, e. cloacae, e. agglomerans, e. gergoviae, hafnia alvei, erwinia carotovora, serratia ... | 1980 | 6104464 |
| inhibition of protein synthesis in intact hela cells by shigella dysenteriae 1 toxin. | shiga toxin purified to near homogeneity from cell lysates of shigella dysenteriae 1 inhibited protein and deoxyribonucle acid syntheses in intact hela cells. inhibition was dependent on toxin concentration and time of incubation. a minimal latent period of 30 min was observed with saturating doses of toxin. ribonucleic acid synthesis, uptake of alpha-aminoisobutyric acid, and maintenance of intracellular k+ concentrations were not affected until well after maximal inhibition of protein and deox ... | 1980 | 6156915 |
| acute diarrheal infections in infants i. bacterial and viral causes. | this first article of a 2-part series examined the epidemiology, therapy, and prospects for immunoprophylaxis of diarrheal infections in infants. 3 main strains of escherichia coli can be identifiied with the etiology of infantile diarrhea: enterotoxigenic e. coli, invasive e. coli, and enteropathogenic e. coli. viral agents may also be the etiological agents. specific pathogens can be identified in 55-85% of cases of infantile diarrhea today; in the 1960s, only 25-34% of cases could be ident ... | 1980 | 6243608 |
| quantitative microtiter cytotoxicity assay for shigella toxin. | the cytotoxic activity of shigella dysenteriae 1 was assayed by exposing hela cells in microtiter cultures to dilutions of toxin. exposure to toxin caused either failure of cells in suspension to attach or detachment of cells from established monolayers. estimates of toxin potency were made by staining residual cells with crystal violet and visually inspecting the stained plates. quantitation of the cytotoxic effect was made possible by eluting and spectrophotometrically measuring the stain. the ... | 1980 | 7012172 |
| interaction of shigella shigae cytotoxin with receptors on sensitive and insensitive cells. | the effect of a cytotoxin isolated from shigella shigae has been tested on different cell lines. hela s3 cells, as well as some other human carcinoma cells, were killed by picomolar to femtomolar concentrations of the pure toxin, whereas certain other human carcinoma cells and a variety of non-epithelial cells from human tissue and from various animal tissues were resistant to-nanomolar concentrations of the toxin. binding studies with 125 i-labelled shigella shigae cytotoxin showed that the sen ... | 1980 | 6895387 |
| plasmids and antibiotic resistance in gram-negative bacteria. | 1980 | 6987459 | |
| prolonged intermittent diarrhea after shiga dysentery: postdysenteric syndrome. | a 42-year-old woman had dysentery caused by the shiga bacillus, shigella dysenteriae type 1, while taking diphenoxylate with atropine during and after her return from a trip to mexico. although she was treated with appropriate antibiotics, she suffered a prolonged and toxic acute course followed by intermittent bouts of diarrhea and abdominal cramping which persisted for two years. the risk of confusing shiga dysentery with ulcerative colitis is illustrated by the presentation, management, and p ... | 1980 | 6987740 |
| shigella toxin inhibition of binding and translation of polyuridylic acid by escherichia coli ribosomes. | shigella toxin inhibits polyuridylic acid-directed polymerization of phenylalanine in ribosome-enzyme systems obtained from escherichia coli or from shigella dysenteriae. the inhibition is the result of toxin acting on ribosomes to prevent polyuridylic acid attachment. | 1980 | 6988411 |
| bacillary dysentery due to multidrug resistant sh. dysenteriae type 1. | 1980 | 6991403 | |
| regulation of tryptophan biosynthesis. | 1980 | 6996563 | |
| [formation of iron-binding metabolites by bacteria of the enterobacteriaceae family]. | the capacity of enterobacteriaceae strains cultivated in a synthetic medium for the biosynthesis of catechols and hydroxamates has been studied. among the strains under study all strains of the genera salmonella (8 strains), escherichia (102 strains), citrobacter (5 strains), enterobacter (2 strains), serratia (1 strain) synthesize catechols. in the genus shigella (128 strains) all sh. flexneri serovars (79 strains) do not synthesize catechols, other representatives of this genus synthesize iron ... | 1980 | 6998212 |
| association of human enteric pathogenicity and mouse lung toxicity of escherichia coli. | mouse lung toxicity of 439 strains (431 escherichia coli, 1 shigella dysenteriae 1, 1 enterobacter cloacae, 5 vibrio sp., 1 klebsiella) was compared to other pathogenicity tests (mouse virulence, enterotoxicity, guinea pig eye test), to serogroup distribution, loss of virulence on storage, origin and haemolytic activity. mouse lethality was highest in serogroup o4 (p < 0.001), o18a,c (p < 0.001); serogroups o6, o20, o75, o115, o147 were next in order. e. coli serogroups o19, o26, o28a,b, o32, o5 ... | 1980 | 6998258 |
| esterase electrophoretic pattern relatedness between shigella species and escherichia coli. | esterases of 57 strains of shigella dysenteriae, sh. flexneri, sh. boydii and sh. sonnei and 26 strains of escherichia coli, including the alkalescens dispar group, were compared by polyacrylamide-agarose gel electrophoresis. six types of esterase bands differing in their ability to hydrolyse synthetic substrates and in their sensitivity to heat and to di-isofluoropropyl phosphate were defined. individual activities and sensitivities of these bands and the apparent molecular weight of the major ... | 1980 | 6999118 |
| randomized trial of high- and low-dose ampicillin therapy for treatment of severe dysentery due to shigella dysenteriae type 1. | to establish optimal therapy for severe dysentery due to shigella dysenteriae type 1 and shigella flexneri, we compared in a prospective randomized trial two oral ampicillin doses (50 and 150 mg/kg per day) in 57 children and 39 adults in dacca, bangladesh. clinical failure did not occur in either group, indicating that conventional doses need not be increased even in severe disease. among children 3 years of age or under, bacteriological relapses tended to be more frequent in the low-dose group ... | 1980 | 6999981 |
| cytotoxicity of shigella dysenteriae 1 for cultured mammalian cells. | the cytotoxicity of an invasive toxigenic wild-type strain of shigella dysenteriae 1 (3818t) was compared with that of noninvasive, toxigenic strain 38180 and hypotoxigenic strain 725. cytolysis of hela or henle 407 cells exposed to these strains was measured by release of (3h) uridine from prelabeled monolayers. hela cells exposed to noninvasive, toxigenic strain 38180, or to partially purified shiga toxin were lysed only after a latent period of more than 8 hr. during this period, protein synt ... | 1980 | 7001884 |
| shigella dysenteriae i enterotoxin: proposed role in pathogenesis of shigellosis. | bacterial strains of shigella dysenteriae i (3818-t and 3818-o) and shigella enterotoxin altered myoelectric activity of the small intestine in new zealand white rabbits. these agents were compared with activity caused by sterile culture broth or sterile saline. the altered myoelectric activity was characterized by two distinct complexes: repetitive bursts of action potentials (rbap), characteristic of invasive strains of bacteria, and the migrating action potential complex (mapc), characteristi ... | 1980 | 7001925 |
| characterization of shigella dysenteriae 1 (shiga) toxin purified by anti-shiga toxin affinity chromatography. | shigella dysenteriae 1 (shiga) toxin was purified from whole-cell lysates by antitoxin affinity column chromatography, radioiodination, and sephacryl s-200 gel filtration of 125i-labeled affinity column eluates. two chromatographic peaks were observed. the percentage of radioactivity in peak i samples immunoprecipitated with antitoxin ranged from 95 to 100%. a pool of samples from this first peak contained over 90% of the hela-cell-cytotoxic units applied to the column and was enterotoxic for ra ... | 1980 | 7002787 |
| isolation and characterization of minicell-producing mutants of shigella spp. | minicells are small, anucleate cells resulting from aberrant cell divisions at the polar ends of bacilli. we have isolated minicell-producing mutant strains of shigella flexneri 2a (mc-i) and shigella dysenteriae 1 (mc-v) after mutagenesis with n-methyl-n'-nitro-n-nitrosoguanidine. microscopically, broth cultures of mc-i and mc-v were found to contain free minicells, normal cells, and filamentous cells with polar, attached minicells. both strains retained their ability to provoke keratoconjuncti ... | 1980 | 7002790 |
| contrasting epidemiology of shigellae dysenteriae and shigellae flexneri, dacca. | 1980 | 7003832 | |
| [characteristics and function of enterotoxins of gram negative bacteria (author's transl)]. | several factors are important for the pathogenesis of bacterial intestinal disease: 1. colonisation of the intestine; 2. exo(= entero)toxin production without penetration into the intestinal wall; 3. invasion of the intestinal wall with or without (?) simultaneous formation of enterotoxin. these factors are of different importance for the various infective agents. whereas cholera is exclusively caused by an enterotoxin, this is of minor importance for the pathogenesis of shigella dysentery. the ... | 1980 | 7005079 |
| survival of shigellae in soil. | the survival of four shigella strains in soil (sh. sonnei, sh. boydii, sh. flexneri and sh. dysenteriae) was studied under various conditions. their survival period was tested in two different types of sterile soil at 18-20 degrees c and in one type of soil at 4 and 37 degrees c. this latter type of soil, after enrichment with casaminoacids or (nh4)2hpo4 was also used for testing again the survival of the strains at 18-20 degrees c. though the initial number of the inoculated microorganisms was ... | 1980 | 7006270 |
| relative potencies of four reference endotoxin standards as measured by the limulus amoebocyte lysate and usp rabbit pyrogen tests. | four commonly used reference endotoxin standards, escherichia coli o113:h10:k0, e. coli o55:b5, salmonella abortusequi, and shigella dysenteriae were compared by the usp rabbit pyrogen and the limulus amoebocyte lysate tests. by the rabbit pyrogen test, s. abortus equi was identified as the most potent endotoxin, followed closely by e. coli o113:h10:k0 and e. coli o55:b5. | 1980 | 7006505 |
| resistance to trimethoprim and other antibiotics in shigellae isolated in the province of ontario. | antimicrobial susceptibility determinations for three commonly used and seven seldom used antibacterial drugs against 482 strains of shigellae isolated in ontario during 1977 and 1978 were carried out. resistance to the first-line treatment drugs, ampicillin and tetracycline, occurred in 20.5 and 39.2% of strains, respectively. the emergence of trimethoprim-sulfamethoxazole resistance was noted for the first time in 3.2% of the strains in 1978. all strains retained their susceptibility to gentam ... | 1980 | 7006767 |
| nucleotide sequences of the trpg regions of escherichia coli, shigella dysenteriae, salmonella typhimurium and serratia marcescens. | 1980 | 7007652 | |
| foodborne outbreak of shigellosis caused by an unusual shigella strain. | a family outbreak of foodborne shigellosis caused by an unusual strain of shigella is described. the strain was a mannitol-positive variant of shigella dysenteriae and agglutinated in antiserum prepared against provisional serotype 3341-55. | 1980 | 6768766 |
| comparative studies on the regulation of tryptophan synthesis. | in vitro dna recombination techniques have revolutionized the study of genetic control of biosynthetic pathways. using examples drawn from the pathway of tryptophan synthesis, approaches to the deciphering of regulatory signals and response mechanisms through transposition of dna segments and dna sequence analysis will be presented. after reviewing the known chromosomal arrangements and regulatory patterns of trp genes in the bacterial groups studied so far, and describing the results of transfe ... | 1980 | 6772375 |
| effects of intravenous and aerosol administration of crude shigella toxin to rhesus macaques: preliminary study. | experiments were conducted to determine the dose response, survival time, blood biochemical changes, and cardiohepatic responses to a single iv injection of crude shigella toxin in rhesus macaques (macaca mulatta). circulatory shock, hepatic falure, respiratory depression, dyspnea, convulsions, and coma were observed before death. the survival time was inversely related to the administered toxic dose, which ranged from 20 to 200 microgram/kg of body weight. however, the severity of lesions in th ... | 1980 | 6773452 |
| [features of the infectious process caused by shigellae of different species]. | 1980 | 6778021 | |
| isolation and characterization of shigella shigae cytotoxin. | shigella shigae cytotoxin was isolated from pressure-dialyzed culture medium and from a 26-year-old sample of partially purified toxin. the toxin was adsorbed to a column of acid-treated chitin at low salt concentration and eluted with 1 m nacl. the partially purified toxin was labeled with 125 i and resubmitted to chromatography on acid-treated chitin. the labeled material eluted with 1 m nacl was mixed with unlabeled rabbit hemoglobin as a carrier and the toxin was further purified by chromato ... | 1980 | 7350160 |
| eosinophil counts in duodenal tissue in cow's-milk allergy. | 1979 | 89421 | |
| virus production by abelson murine leukemia virus-transformed lymphoid cells. | cell lines obtained by in vitro transformation of bone marrow with abelson murine leukemia virus (a-mulv) can be divided into three classes: producers, releasing reverse transcriptase-containing particles and infectious virus; nonproducers, releasing no viral particles; and defective producers, the most common phenotype, releasing particulate reverse transcriptase in the absence of infectious virus. when such cell lines were analyzed 1 to 2 weeks after their isolation, however, all produced infe ... | 1979 | 90175 |
| the intra-nucleolar localization of amplified rdna in xenopus laevis oocytes. | a fluorescent feulgen-stain was adapted in order to demonstrate dna-containing structures inside the amplified nucleoli of xenopus laevis. at all stages of oogenesis this method reveals granules or complex structures of dna in each nucleolus. the micronucleoli which do not stain with this method and which do not reveal an internal structure in low molarity saline, unlike real nucleoli are considered as nucleolus-like bodies. the dna-containing structures in the nucleoli can be composed of one or ... | 1979 | 90588 |
| characterization of a type-c virus produced by co-cultures of human leukemic bone-marrow and fetal canine thymus cells. | the putative human helper virus ska-21/a204v, isolated by nooter et al. in 1977 from human leukemic bone-marrow cells following co-culture with normal fetal canine thymus cells, cf2th, has been characterized with respect to its major viral core protein, reverse transcriptase, and nucleic acid sequences. the results of these analyses show that this virus is not distinguishable from the woolly monkey type-c virus, ssav-1, by the techniques employed. | 1979 | 90662 |
| latex fetuin spheres as probes for influenza virus neuraminidase in productively and abortively infected cells. | fetuin bound latex spheres do not adhere to the membranes of non-infected cells but adhere to those of cells productively infected by fowl plague virus (fpv dobson strain). in contrast, asialo fetuin spheres do not attach to the membranes of productively infected cells. moreover latex fetuin spheres incubated with extracts of productively infected cells and extensively washed are specifically enriched in neuraminidase activity without any trace of haemagglutinin. these observations suggest that ... | 1979 | 91354 |
| connectivity of the auditory forebrain nuclei in the guinea fowl (numida meleagris). | injection of tritiated leucine and proline into the nucleus ovoidalis of the guinea fowl (numida meleagris) produces terminal labeling in the palaeostriatum and in three adjacent zones (field l1-l3) of the auditory neostriatum (an). l2, situated between l1 and l3, receives the main input and corresponds to the former field l of rose. these neuroanatomically defined zones of the auditory neostriatum are also characterized by differing properties of their neurons. injection of radioactive material ... | 1979 | 91442 |
| short latency mechanically evoked somatosensory potentials in humans. | somatosensory potentials evoked by mechanical stimulation were recorded by surface electrodes over (1) the digital nerves in the index finger, (2) the median nerve at the wrist, (3) the median nerve near the axilla, (4) the brachial plexus, (5) the cervical cord at cii, (6) the scalp overlying the somatosensory cortex. nerve conduction velocities varied inversely with age and ranged from 43 to 68 m/sec. mechanically evoked potentials recorded from the electrodes overlying the digital nerves were ... | 1979 | 91479 |
| antigen specific t cell-mediated suppression. vi. properties of in vitro generated l-glutamic acid60-l-alanine30-l-tyrosine10 (gat)-specific t-suppressor factor(s) (gat-tsf) in responder mouse strains. | 1979 | 91643 | |
| presence of plasma cells binding autologous antibody during an immune response. | spleen and other lymphoid tissues of rabbits immunized with human serum albumin (hsa) and human lactoferrin (lf) were examined for the presence of cells forming anti-idiotype antibodies. to detect these cells, igg, f(ab')2, or fab' of specific antibodies were isolated, fluorochrome-tagged with tetramethylrhodamine isothiocyanate, and used as an idiotypic marker to detect splenic plasma cells that are producing anti-idiotypic antibody. by this procedure, we were able to demonstrate anti-idiotypic ... | 1979 | 91659 |
| indomethacin, arachidonic acid metabolism and basophil histamine release. | 1979 | 91953 | |
| [influence of a dialyzable serum factor on the activity of beta-galactosidase from human liver (proceedings)]. | 1979 | 92267 | |
| studies on the activation of canine trypsinogens in vitro. | the activation of canine anionic and cationic trypsinogen by enterokinase, trypsin, thrombin, plasmin and extracts from canine granulocytes were studied in vitro. enterokinase activates both trypsinogens about 1000 times faster than trypsin. the enterokinase-catalyzed activation is not inhibited by the main serum protease inhibitors, alpha-macroglobulin and alpha 1-antitrypsin. alpha-macroglobulin cannot inhibit the activation of the trypsinogens by trypsin but this reaction is completely inhibi ... | 1979 | 92342 |
| [clinical effects of chlormadinone acetate (cma) on human benign prostatic hypertrophy--comparative study with hexestrol by a double blind trial (author's transl)]. | 1979 | 92377 | |
| fetotoxicity and cataractogenicity of mirex in rats and mice with notes on kepone. | 1979 | 92402 | |
| populational polymorphisms in silver staining of nucleolus organizer regions (nors) in human acrocentric chromosomes. | the ag stainability of the nucleolus organizer region (nor) was studied in the acrocentric chromosomes identified by q banding of cultured lymphocytes in 41 karyotypically normal persons (33 males and 8 females) originating from southeast estonia. the data obtained are compared with those established earlier for a combined vienna-ulm population of 51 karyotypically normal persons (see mikelsaar et al., 1977a). significant differences between the two populations in the frequency and patterns of a ... | 1979 | 92452 |
| nonspecific light loss and intrinsic dna variation problems associated with feulgen dna cytophotometry. | nonspecific light loss by the cell-wall-plus-cytoplasm (cwc) can cause a 50% increase in feulgen absorption units in peanut root-tip nuclei as determined by scanning at 450 nm, whereas this phenomenon is not evident with chicken erythrocytes. a two wavelength scanning method of subtracting nonspecific 450 nm absorption from 550 nm feulgen absorption values eliminated the nonspecific light loss in cwc, however, the two wavelength scanning method is time consuming and somewhat impractical with a r ... | 1979 | 92496 |