Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| effects of a high-sucrose diet on the development of enzyme-altered foci in chemical hepatocarcinogenesis in rats. | dietary factors can modify metabolic events involved in the initiation, promotion, or progression of tumors. to determine whether a high-sucrose diet has any effect on the development of enzyme-altered foci during the promotion step of chemical hepatocarcinogenesis in rats, 1-day-old sprague-dawley rats were given a single i.p. dose of diethylnitrosamine; controls received an equivalent i.p. volume of 0.9% nacl solution. at 21 days of age, the rats were weaned, segregated by sex, separated in gr ... | 1985 | 2859110 |
| effects of a high-sucrose diet on the development of enzyme-altered foci in chemical hepatocarcinogenesis in rats. | dietary factors can modify metabolic events involved in the initiation, promotion, or progression of tumors. to determine whether a high-sucrose diet has any effect on the development of enzyme-altered foci during the promotion step of chemical hepatocarcinogenesis in rats, 1-day-old sprague-dawley rats were given a single i.p. dose of diethylnitrosamine; controls received an equivalent i.p. volume of 0.9% nacl solution. at 21 days of age, the rats were weaned, segregated by sex, separated in gr ... | 1985 | 2859110 |
| epidemic shiga bacillary dysentery in rangoon, burma, 1984/85. | 1985 | 2861376 | |
| evidence against putrescine and polyamines as endogenous mediators of fever. | endogenous concentrations of putrescine, spermidine, spermine and related biosynthetic enzymes were not affected by the administration of bacterial endotoxin and the subsequent development of fever in rabbits. in addition, the febrile response to endotoxin was unaffected either by the ornithine decarboxylase inhibitor, dl-alpha-difluoromethylornithine or by putrescine. these data indicate polyamines are not involved in the development of fever. | 1985 | 2862252 |
| multiresistant shigella infections in bangladesh. | 1985 | 2863461 | |
| immunocytochemical studies of somatostatin neurons in brain. | immunohistochemical studies with antisera to somatostatin have, in many instances, led the way to our present understanding of the peptidergic nervous system. somatostatin was among the first of the hypophysiotropic hormones shown to be contained in diverse neuronal circuits outside of the hypothalamus. for example, somatostatin is found within neurons ranging in location from the cerebral cortex to primary sensory neurons to enteric neurons within the gut wall. somatostatin was also the first n ... | 1985 | 2863929 |
| two distinct toxins active on vero cells from escherichia coli o157. | 1985 | 2864594 | |
| multiresistant shigella dysenteriae type 1. | 1985 | 2865444 | |
| axonally transported shigella cytotoxin is neuronotoxic. | shigella dysenteriae strains produce an exotoxin (sdt) which inhibits protein synthesis in susceptible cells and is neurotoxic in some species. intraneural microinjection of highly purified sdt into the cervical vagus nerves of rats, mice, guinea pigs and rabbits produced cytopathic changes within 24 hours in vagal sensory but not motor neurons. these changes consisted of an initial loss of nissl substance followed by progressive cell degeneration and resulted in permanent neuronal loss. indirec ... | 1985 | 2411880 |
| 'o'-antigens are essential virulence factors of shigella sonnei and shigella dysenteriae 1. | a novel transposon mutagenesis system has been developed for shigella. we have used it to isolate specific mutants of shigella sonnei and shigella dysenteriae 1 that fail to produce lipopolysaccharide 'o' side chains. the virulence of the mutants was evaluated in the sereny test and in a hela cell invasion assay. all ho'-minus mutants failed to provoke a positive sereny reaction but retained the ability to invade hela cells. this demonstrates that 'o' side chains are virulence factors of s. sonn ... | 1985 | 2413650 |
| inactivation by polymyxin b of the endotoxin-mediated interferon production in the rabbit. | polymyxin b (pb) completely or at least significantly inhibited the capacity of shigella dysenteriae 1 cells and the lipopolysaccharide (lps) and lipid a (la) subunits of several bacterial endotoxins to induce interferon (ifn) in rabbits. animals injected with lps inactivated by pb to the point of not inducing detectable ifn levels did not develop hyporesponsiveness to secondary ifn induction by a homologous inducer. it was concluded that pb inhibits the ifn-inducing capacity of endotoxin and it ... | 1985 | 2413651 |
| [vital staining of the conjunctiva for prevention of epithelial implantation cysts]. | selective vital staining with 1% toluidine blue makes short-term intraoperative differentiation of the conjunctiva from tenon's capsule possible. it is used with advantage in operations where the anatomical situation is unclear to avoid displacement of conjunctival epithelium into deeper tissues and subsequent growth of cysts. examples of its application are reoperations with excessive scars after squint or detachment surgery, wound dehiscence after enucleations, lacerated wounds after accidents ... | 1985 | 2415747 |
| cellular mechanism of the relationship between myocardial force and frequency of contractions. | 1985 | 3331452 | |
| effective induction immunosuppression for cadaver renal transplantation at the st. francis regional medical center. | the okt3 induction protocol, when compared to a conventional drug protocol, resulted in an improvement in both short- and long-term patient and graft survival, especially in patients receiving a primary transplant. the 1-year allograft survival in primary transplants receiving okt3 induction was 91% and the t1/2 of 13.5 years. this was accomplished while still being able to minimize the total drug dose of aza, pred, and csa, thereby minimizing clinical complications. the use of okt3 did not incr ... | 1985 | 2129408 |
| when is treatment economically justified? | 1985 | 2041026 | |
| pharmacotherapy i: non-narcotic analgesics. | 1985 | 271621 | |
| comparison of minimum inhibitory concentration of water soluble extracts of eugenia jambolana lam. (fam. myrtaceae) barks of different ages on dysentery and diarrhoea forming micro - organisms. | a preliminary investigations was carried out to study the antibacterial activity of the water soluble extracts of five and ten years old barks of eugenia jambolana lam. (fam. myrtaceae) on dysentery and diarrhoea forming micro organisms. it was observed that the barks of young plants have a better inhibitory effect on micro - organisms like salmonella viballerup, shigella dysenteriae 10, shigella boydii 5, sgigella dysenteriae 2. | 1985 | 22557509 |
| mixed connective tissue disease presenting as a left sided pleural effusion. | mixed connective tissue disease (mctd) usually occurs in women aged 13-50 years. pleural effusion is rarely the presenting feature of this disease. the case is reported here of a male patient with mctd who presented at the age of 79 years with a left sided pleural effusion. | 1984 | 1444629 |
| extracoronal amalgam restorations utilizing available tooth structure for retention. | 1984 | 264320 | |
| the management of ruptured intracranial aneurysms. | 1984 | 263409 | |
| [pregnancy and the single mother]. | 1984 | 261420 | |
| immunoblotting procedure for the analysis of electrophoretically-fractionated bacterial lipopolysaccharide. | a procedure is described for the efficient transfer of fractionated bacterial lipopolysaccharide (lps) from sds-polyacrylamide gels to nitrocellulose filters, and its subsequent display by a peroxidase-linked antibody. the method is sensitive, and reveals and resolves high molecular weight lps molecules having side chain lengths of up to and greater than 30 repeat units. it is useful for the rapid analysis of lps in bacterial outer membrane preparations. | 1984 | 6084988 |
| epidemic bacillary dysentery in west bengal, india, 1984. | 1984 | 6145892 | |
| nalidixic acid in shigella dysenteriae outbreaks. | 1984 | 6146074 | |
| shiga bacillus: west bengal to bristol. | 1984 | 6146826 | |
| epidemic of dysentery in west bengal: clinicians' enigma. | 1984 | 6150220 | |
| environmental and human isolates of vibrio cholerae and vibrio parahaemolyticus produce a shigella dysenteriae 1 (shiga)-like cytotoxin. | some strains of vibrio parahaemolyticus, vibrio cholerae, and non-o1 v cholerae produce a bacterial-cell-associated, heat-stable material that is cytotoxic for hela cells. cytotoxicity is completely neutralised by antibody to purified shigella dysenteriae 1 (shiga) toxin but not by antibody to purified cholera toxin. | 1984 | 6140426 |
| comparative study of the nature and biological activities of bacterial enterotoxins. | it is apparent that there are considerable similarities between many of the enterotoxins produced by enteric pathogens. although the effect of most of these toxins is restricted to the intestine in vivo, many cells are also sensitive to intoxication in vitro. the resultant in-vitro biochemical changes may have no pathological significance but serve to underline the central role of cyclic nucleotides in cellular fluid regulation. the biological activity of these enterotoxins is the result of inte ... | 1984 | 6327986 |
| comparative efficacies of pivmecillinam and ampicillin in acute shigellosis. | the clinical efficacies of pivmecillinam and ampicillin were compared in a randomized double-blind trial in the treatment of acute shigellosis. of 44 adult male patients, all culture positive for shigella strains, 22 patients received 400 mg of pivmecillinam and 22 patients received 500 mg of ampicillin every 6 h. both drugs were administered orally for 5 days. four patients receiving ampicillin were infected with shigella strains that were resistant to ampicillin but susceptible to pivmecillina ... | 1984 | 6329092 |
| [neutralizing action of human blood preparations on shigella enterotoxins and choleragen]. | the possibility of neutralizing the enterotoxic activity of s. dysenteriae 1 neurotoxin, s. sonnei live virulent cultures and cholerigen with immune sera of different animals, normal human sera and commercial gamma-globulin preparations is shown. | 1984 | 6205524 |
| temperature-dependent expression of virulence genes in shigella species. | the pathogenicity of shigella spp. involves the ability of the bacteria to penetrate and replicate within the epithelial cells of the large intestine. model systems for examining the virulence of shigellae employ henle intestinal epithelial cells in tissue culture and an in vivo assay for virulence in guinea pig eyes (sereny test). using these systems, we studied the genetic and physiological bases for the ability of shigellae to invade epithelial cells. we found that expression of virulence in ... | 1984 | 6360895 |
| a small plasmid in shigella dysenteriae 1 specifies one or more functions essential for o antigen production and bacterial virulence. | the role of plasmids in the virulence of shigella dysenteriae 1 w30864, which contains at least five species, was investigated. by means of a standard plasmid-curing procedure, that is, bacterial cultivation at an elevated temperature, five virulence-deficient derivatives were obtained. one of these lacked a small, 6-megadalton plasmid, designated phw400, exhibited reduced invasiveness for hela cells, and failed to produce the somatic antigen. transposon tagging of the phw400 plasmid to produce ... | 1984 | 6360905 |
| purified shigella enterotoxin does not alter intestinal motility. | a purified shigella enterotoxin (pst) and a cell-free lysate with pst removed (cfl-pst) from the whole-cell lysate of shigella dysenteriae 60 r were used to study their effect on the myoelectric activity and mucosal integrity of rabbit ileal segments. we have previously defined two myoelectric patterns: the migrating action potential complex and repetitive bursts of action potentials that occur in response to certain bacteria and their enterotoxins. the in vivo model consisted of isolated ileal ... | 1984 | 6363286 |
| shiga toxin: no smoking gun. | 1984 | 6364352 | |
| r plasmids conferring multiple drug resistance from shigella isolated in korea. | the majority (85%) of shigella isolated in 1980 and 1981 in korea were shigella flexneri, the others were sh. sonnei (14%) with only a small number of sh. dysenteriae. only 14 of the 459 strains of shigella isolated were susceptible to all 12 drugs tested, and 445 were resistant to three or more drugs. strains multiply resistant to the six drugs, chloramphenicol (cm), tetracycline (tc), streptomycin (sm), sulfisomidine (su), ampicillin (ap) and trimethoprim (tp) were most frequently encountered, ... | 1984 | 6368684 |
| shigella dysentery in tripoli, libya. | 1984 | 6371260 | |
| changes in the trend of shigellosis in dhaka: family study on secondary infection, clinical manifestation and sensitivity pattern: 1980. | the incidence of shigellosis and the death rate have increased and the resistance of shigellae to antibiotics has changed in dhaka during our experiences. in 1980, we investigated the secondary infection and case rates, infection to case ratio, duration of illness, excretion of shigellae and antibiotic sensitivity pattern in 100 families with cases of shigellosis, culturing rectal swabs obtained by home visits for a 10-day period. standard methods were used for culture and sensitivity tests. the ... | 1984 | 6380011 |
| effect of bacterial endotoxin on body temperature, plasma zinc and plasma concentrations of the acute-phase protein serum amyloid p component in mice. | bacterial endotoxin and lipid a evoked dose-dependent increases in body temperature and plasma sap concentrations and dose-dependent falls in plasma zinc concentrations in mice. the respective sensitivities of the three variables to lipid a or to whole endotoxin had the relation sap greater than zinc much greater than body temperature; zinc and sap responses were evoked by less than 1 ng lipid a/endotoxin. pretreatment with indomethacin prevented only the temperature response to lipid a. pretrea ... | 1984 | 6380557 |
| small virulence plasmid of shigella dysenteriae 1 strain w30864 encodes a 41,000-dalton protein involved in formation of specific lipopolysaccharide side chains of serotype 1 isolates. | a 6-megadalton plasmid, phw400, of shigella dysenteriae 1 strain w30864 was previously found to specify one or more functions for o-antigen production and bacterial virulence (h. watanabe and k. n. timmis, infect. immun. 43:391-396, 1984). the region of phw401, a tn801-tagged derivative of phw400, responsible for o-antigen production has been localized by gene cloning and tn5 transposon mutagenesis. analysis of lipopolysaccharide isolated from s. dysenteriae 1 bacteria carrying mutant plasmids r ... | 1984 | 6384048 |
| [a patient with a complicated course of shigellosis]. | 1984 | 6384800 | |
| the humoral antibody response to shigella dysenteriae type 1 infection, as determined by elisa. | an enzyme-linked immunosorbent assay (elisa) for determining the class-specific humoral antibody response to the lipopolysaccharide antigen from shigella dysenteriae serotype 1 bacteria has been tested. two or more serum samples from each of 60 persons infected with this organism during a dysentery outbreak in a boarding school for young men near haiphong, viet nam, and single serum samples from 39 healthy vietnamese and from 20 healthy swedes were included in the study. comparison of the titres ... | 1984 | 6386207 |
| usefulness of plasmid profiles for differentiation of shigella isolates in bangladesh. | we studied the plasmid profiles of 136 shigella isolates in bangladesh to determine whether plasmid profiles could be used for differentiation of strains for epidemiological studies. many different plasmid patterns were observed within each species, indicating that many genetically different strains of shigella are responsible for illness in bangladesh. | 1984 | 6386850 |
| expression of lipopolysaccharide o antigen in escherichia coli k-12 hybrids containing plasmid and chromosomal genes from shigella dysenteriae 1. | the requirement for both plasmid and chromosomal genes in the biosynthesis of shigella dysenteriae 1 lipopolysaccharide o antigen was demonstrated in escherichia coli-shigella hybrids. a 6-megadalton s. dysenteriae 1 plasmid, designated pwr23, was phenotypically tagged with the tn3 ampicillin-resistance transposon. the tagged plasmid, designated pwr24, was transferred by transformation or conjugal mobilization to a rough e. coli k-12 recipient. although the resultant hybrids were agglutinated in ... | 1984 | 6389345 |
| epidemic dysentery caused by the shiga bacillus in a southern indian village. | multi-drug resistant shigella dysenteriae type 1 caused an epidemic of dysentery in a village in southern india. the epidemic started as a common source outbreak, through the piped water supply of the village with subsequent person-to-person spread. although the attack rate was high, with nearly 1/2 the children under age 5 being affected, the case fatality rate was only about 1%. of the 248 patients who attended the field clinic, 89.4% passed small mucoid stools mixed with blood, with the ma ... | 1984 | 6389664 |
| [bacillary dysentery 1982]. | 1984 | 6390523 | |
| epidemic shiga bacillus dysentery in central africa. | an outbreak of dysentery began late in 1979 in central africa and spread to involve a major portion of zaire as well as rwanda and burundi. we traveled to a mission hospital in northeast zaire during the epidemic and isolated shigella dysenteriae, type 1, from most of the patients studied. all isolates were resistant to ampicillin, tetracycline, chloramphenicol, sulfathiazole, and streptomycin but sensitive to trimethoprim-sulfamethoxazole. antimicrobial resistance was transferable to escherichi ... | 1984 | 6391226 |
| [molecular structure of the o-specific polysaccharide of shigella dysenteriae type 2]. | 1984 | 6391882 | |
| pathogenesis of shigella diarrhea. ix. simplified high yield purification of shigella toxin and characterization of subunit composition and function by the use of subunit-specific monoclonal and polyclonal antibodies. | a simple purification scheme for shigella cytotoxin was devised, resulting in high yields (approximately 50%) and a 1,300-fold increase in specific activity compared with the initial crude bacterial cell lysate. the purified toxin was enterotoxic in ligated rabbit ileal loops and neurotoxic when injected into the peritoneal cavity of mice. measurement of specific activity of cytotoxin and enterotoxin demonstrated that these two toxicities copurify during the fractionation procedure. on sodium do ... | 1984 | 6392471 |
| [the local epidemic of shigella dysenteriae in wuwei county, gansu province]. | 1984 | 6394140 | |
| shigellemia. | 1984 | 6394497 | |
| [shigella dysenteriae in our environment]. | 1984 | 6394922 | |
| shigellosis: an old disease with new faces. | 1984 | 6397507 | |
| an epidemic of blood and mucus diarrhoea complicated by disseminated intravascular coagulation. | 1984 | 6399690 | |
| drug resistance in shigella dysenteriae, s flexneri and s boydii in england and wales: increasing incidence of resistance to trimethoprim. | a total of 2753 strains of shigella belonging to subgroups a, b, and c that were isolated from patients in england and wales during the period from 1979 to mid-1983 were studied. of these, 1690 (61%) were from patients recently returned from abroad or in contact with recent travellers, and 760 (45%) of these affected travellers from the indian subcontinent. the number of strains resistant to sulphonamides and streptomycin remained at a high level throughout (average 76% and 72% respectively). re ... | 1984 | 6423079 |
| [clinical and laboratory studies on acute bacterial diarrhea]. | 1984 | 6437636 | |
| the leukemoid reaction in shigellosis. | leukemoid reactions occurred in 136 patients (3.8%) hospitalized with shigellosis in bangladesh. sixty-eight percent of the patients with leukemoid reactions were children less than 4 years old. when compared with patients without leukemoid reactions, the leukemoid reactions were significantly associated with children aged less than 10 years. the most common serotype of shigella in the patients with leukemoid reactions was shigella dysenteriae 1, isolated from 96 patients (71%), whereas the most ... | 1984 | 6695872 |
| [recent advances in the molecular mechanism of action of bacterial toxins, in particular of diphtheria, cholera, coli, botulinum and shigella toxins as well as tetanospasmin and the toxins of staphylococcus aureus]. | great progress was achieved in the clarification of the molecular structure and the mechanism of action of the toxins of pathogenic forms of bacteria. proportions of toxins of corynebacterium diphtheriae and of pseudomonas aeruginosa transfer from the nad and adp-ribose protein to an amino acid of the elongation factor 2. thus the protein synthesis is much inhibited. the cholera toxin and the l-toxin from escherichia coli have a similar structure. they transfer an adp-ribose portion from nad to ... | 1984 | 6375175 |
| dried filter paper for sending dysenteric faeces to the laboratory. a neglected method? | 1984 | 6375592 | |
| circulating antisomatic antibody response in shiga dysentery & igm & igg activities after 2-mercaptoethanol treatment. | 1984 | 6378776 | |
| [arthritis in shigella and salmonella infections]. | 1984 | 6379799 | |
| [shigellosis abroad]. | 1983 | 6379992 | |
| shigella dysenteriae 1 cytotoxin: periplasmic protein releasable by polymyxin b and osmotic shock. | treatment of shigella dysenteriae 1 either with the antibiotic polymyxin b or by osmotic shock resulted in the release of 80 to 90% of the cytotoxin activity of the organism. under the conditions employed, the release of toxin activity was accompanied by the appearance of a periplasmic enzyme, 5'-nucleotidase. there was no significant release of cytoplasmic contents, assessed by measurement of glucose-6-phosphate dehydrogenase activity. the release of cytotoxin and 5'-nucleotidase by polymyxin b ... | 1983 | 6295958 |
| release of shiga toxin from shigella dysenteriae 1 by polymyxin b. | release of shiga toxin from shigella dysenteriae 1 was found to occur after exposure to polymyxin b. the amount of toxin released was dependent on both the polymyxin concentration and time of incubation. an immunoblot characterization of the shiga toxin released by polymyxin treatment demonstrated that it is electrophoretically similar to purified shiga toxin and to shiga toxin present in crude bacterial sonicates of s. dysenteriae 1 cells. | 1983 | 6299964 |
| peripheral neuropathy following shigella dysentery. | 1983 | 6316568 | |
| hospital-associated outbreak of shigella dysenteriae type 2--maryland. | 1983 | 6405168 | |
| shigella dysenteriae bacteremia. | 1983 | 6889165 | |
| immunochemical studies on shigella dysenteriae type 10 bacterial polysaccharide. | on graded hydrolysis and smith degradation, the o-somatic polysaccharide isolated from shigella dysenteriae type 10 bacteria yielded four oligosaccharides which were characterized by methylation studies. immunochemical studies using constituent monosaccharides and the oligosaccharides indicated that the sugar grouping leads to 3)-mannac-(1 leads to 3)-rha-(1 leads to 4)-glcnac-(1 leads to was the immunodominant part in the polysaccharide molecule, and that 2-acetamido-2-deoxy-d-mannose contribut ... | 1983 | 6200225 |
| immunochemical studies on a polysaccharide from shigella dysenteriae type 2. | the polysaccharide isolated from shigella dysenteriae type 2, strain nctc 566, on smith degradation and graded hydrolysis yielded three oligosaccharides which were characterised using methylation studies. using homologous rabbit antiserum and the monosaccharides that constituted the polysaccharide and the oligosaccharides isolated from it and the cross-reactions in some type-specific pneumococcal antisera, immunochemical specificities of different sugar groupings in the polysaccharide molecule w ... | 1983 | 6371498 |
| [transfer of h2s plasmid from e. coli to shigella]. | 1983 | 6374333 | |
| [diagnostic test system for the quantitative determination of shigella antigens in patient blood by an immunoenzyme analytical method]. | the diagnostic test system under trial has been shown to permit the detection of s. sonnei and s. flexneri specific antigens with an accuracy of 10(-3) micrograms. along with high sensitivity, the test system has sufficiently high specificity. statistically significant differences in the occurrence of specific dysentery antigens and their levels in the blood of dysentery patients and healthy persons have been revealed. | 1983 | 6362300 |
| studies of enterotoxin of shigella dysenteriae type 1. i. effect of aeration on the production of enterotoxin and suitability of laboratory animals for its biological assay. | shigella dysenteriae type 1 was used to study the influence of aeration on enterotoxin production and the suitability of laboratory animals for the toxin assay. the enterotoxin produced under aerobic shake culture conditions gave a gut dilatory response of 1.436 but that obtained in aerobic and anaerobic stationary cultures exerted no activity. the toxin fractionated on sephadex g-150 column was more effective than that obtained by ammonium sulphate precipitation. only sephadex column fraction i ... | 1983 | 6362316 |
| [theoretical conformation analysis of specific o-antigenic polysaccharides. polysaccharide of shigella dysenteriae of serotype 2]. | theoretical conformational analysis of shigella dysenteriae serotype 2 polysaccharide containing repeating unit: -4gal beta 1-3galnac alpha 1-3(glcnac alpha 1-4)galnac alpha 1-4glc alpha 1- has been carried out. it is shown that spatial forms of the polymer are determined by conformational states of glc alpha 1-4gal links which form the internal bends of the chain. the structures of low energy are shown to be left three-fold helices with an axially projected repeat of approximately 12 a. n-aceta ... | 1983 | 6207841 |
| immunochemical studies on shigella dysenteriae type 9 bacterial polysaccharide. | on graded hydrolysis and smith degradation, the o-somatic polysaccharide isolated from shigella dysenteriae type 9 bacteria, strain nctc 7919, yielded five oligosaccharides which were characterized. the positions of the o-acetyl and pyruvic acetal groups in the repeating unit were identified. immunochemical studies indicated that d-galactose is the immunodominant sugar in the polysaccharide, and one of the oligomers, having the structure gal-(1 leads to 3)-glcnac-(1 leads to 3)-gal-(1 leads to 4 ... | 1983 | 6189606 |
| antigenic relationships between the enteroinvasive escherichia coli o antigens o28ac, o112ac, o124, o136, o143, o144, o152, and o164 and shigella o antigens. | enteroinvasive escherichia coli strains have been found in the following o serogroups: o28ac, o112ac, o124, o136, o143, o144, o152, and o164. the biochemical reactions of these enteroinvasive e. coli strains are often similar to those of shigella strains, and identification may be difficult. the problem of differentiation and identification is further complicated by the sharing of antigenic components. the antigenic relationships between these o antigens and those of all the established and prov ... | 1983 | 6189854 |
| animal toxicity of shigella dysenteriae cytotoxin: evidence that the neurotoxic, enterotoxic, and cytotoxic activities are due to one toxin. | the lethal effect to rabbits and mice of shigella dysenteriae toxin and the ability of the toxin to induce fluid accumulation in rabbit ileal loops were studied in relation to the cytotoxic activity. the relative concentrations of the three activities were approximately the same in a crude toxin preparation and in purified, electrophoretically homogenous toxin. the cytotoxic and lethal activities eluted identically from a high pressure liquid chromatography column and migrated at the same rate i ... | 1983 | 6336624 |
| rapid method for detection, identification, and susceptibility testing of enteric pathogens. | three hundred and seven colonies believed to be enteric pathogens were selected from primary plates of macconkey, xylose desoxycholate, or salmonella-shigella agar for inoculation to lactose-sucrose broth, urea-41 motility medium, modified andrade glucose broth with inverted durham tube, pregrowth broth, triple sugar iron agar, lysine iron agar (lia), and christensen urea agar. the rapid screen consisted of interpreting the lactose-sucrose, urea-41 motility, and modified andrade glucose broth ga ... | 1983 | 6338037 |
| shigellosis with bacteremia: a report of two cases and a review of the literature. | it is widely believed by both physicians and microbiologists that bacteremia is a rare event in shigellosis. we report two cases of shigellosis with positive blood cultures and review 68 cases reported in the literature between 1963 and 1981. we suggest that detection of bacteremia in shigellosis may be facilitated by a greater awareness of the following findings. 1. eighty-seven percent of all cases of shigellosis with bacteremia reported in the literature during the 18-year period reviewed occ ... | 1983 | 6340078 |
| purification and characterization of a shigella dysenteriae 1-like toxin produced by escherichia coli. | a toxin from an enteropathogenic strain of escherichia coli (e. coli h30) was purified to apparent homogeneity from cell lysates. the steps used to isolate the e. coli h30 toxin included french pressure-cell disruption of bacteria grown in iron-depleted media. affi-gel blue chromatography, chromatofocusing, and anti-shiga toxin affinity chromatography. the mobilities of the subunits of radioiodinated e. coli h30 toxin and shiga toxin observed after the two toxins were subjected to sodium dodecyl ... | 1983 | 6341244 |
| shigella infections in the united states, 1974-1980. | during the seven-year period 1974-1980, 93,516 shigella isolates from humans were reported to the centers for disease control, atlanta, through a nationwide surveillance system. over the past 30 years, the reported incidence of shigellosis has been declining in contrast to that reported for salmonellosis. shigella sonnei (group d) now accounts for approximately 70% of the shigella isolates reported, since most of the decline has been due to the increasingly less frequent infections caused by shi ... | 1983 | 6341480 |
| [epidemiology of bacillary dysentery in algeria. i. the epidemiological aspects of dysentery in algeria]. | bacterial dysentery plays an important role among infectious diseases in algeria. a tendency to the growth of the morbidity rate has been observed. dysentery is irregularly spread in different zones of the country. the highest morbidity rate is registered in the sahara zone and in the eastern part of the country. the morbidity rate among the urban population is higher than among the rural population. s. flexneri prevail in the etiological structure of dysentery infection. of all age groups, the ... | 1983 | 6342313 |
| leads from the mmwr. shigella dysenteriae type 2 outbreak in us naval hospital. | 1983 | 6343642 | |
| multiple enteric pathogens in travelers from endemic areas: case report. | 1983 | 6344046 | |
| [eternal return... the reappearance of shiga bacillus in central africa]. | 1983 | 6344812 | |
| outbreak of shigella dysentery in eastern zaire, 1980-1982. | 1983 | 6344814 | |
| isolation and characterization of monoclonal antibodies to shiga toxin. | hybridoma cell lines which produce monoclonal antibodies to shiga toxin from shigella dysenteriae 1 were prepared. the monoclonal antibodies were all of the immunoglobulin g1 isotype and differed in their ability to neutralize cytotoxicity and to bind to shiga toxin in a solid-phase radioimmunoassay. when used for immunoblot analysis, these antibodies were able to identify specifically both nicked and unnicked shiga toxin in crude lysates of s. dysenteriae. | 1983 | 6345399 |
| [new directions in the study of immunity in dysentery]. | 1983 | 6346759 | |
| [causes of sequential changes in the etiological structure of dysentery and the other epidemiologic patterns of this infection]. | 1983 | 6349187 | |
| trimethoprim-sulphamethoxazole-resistant shigella dysenteriae serotype 1 (shiga's bacillus) in gimira, south-west ethiopia. | 1983 | 6354711 | |
| pathogenesis of shigella diarrhea. viii. evidence for a translocation step in the cytotoxic action of shiga toxin. | shigella toxin interacts with hela cells by binding to a glycoprotein cell surface receptor and, after a lag period, inactivates the 60s ribosomal subunit and inhibits protein synthesis. the lag period may be due to energy-dependent translocation of the toxin to the interior of the cells. this step was investigated with agents known to inhibit glucose metabolism, mitochondrial energy production, or macromolecular synthesis and with drugs that alter the cytoskeletal system or lysosomes. metabolic ... | 1983 | 6355319 |
| [topology of the structural proteins of long tail fibers of phages t4d, ddvih+ and ddvih]. | topology of the products of the genes 34, 35, 36 and 37 of the bacteriophage t4d long tail fibers were determined with the aid of monospecific antibodies. the antibodies against gene product 34 were the only to interact with the proximal part of long tail fibers, but the distal part bound the antibodies against 35, 36 and 37. product of the gene 35 is located at the joint-site with the distal part and binds the distance not more than 75 a long. gene product 36 is located between these of 35 and ... | 1983 | 6355821 |
| [trends in the spread of boyd 4 dysentery and the characteristics of its clinical picture and of the biology of its causative agent]. | the data on the proportion of s. boydii 4 in the general structure of the causative agents of dysentery, as well as in the intraspecific structure of s. boydii, in some areas of the ussr in 1977-1981 are presented. s. boydii strains 4, circulating in one of the areas where their proportion considerably increased in 1980-1981, corresponded to their taxonomic position in their biological properties, while forming a single biochemical variant according to the character of the fermentation of sorbit ... | 1983 | 6356722 |
| molecular comparison of virulence plasmids in shigella and enteroinvasive escherichia coli. | virulent isolates of shigella dysenteriae and shigella boydii harboured a 140 mdal plasmid which was either absent or deleted in spontaneously avirulent strains. together with previous data concerning s. sonnei, s. flexneri and enteroinvasive escherichia coli, the present results established the general role of extrachromosomal elements in the virulence of such enteroinvasive species. among different species, these virulence plasmids showed unrelated endonuclease cleavage patterns, whereas hybri ... | 1983 | 6357023 |
| entry of shigella dysenteriae toxin into hela cells. | the rate of shigella toxin entry into the cytosol of hela s3 cells was estimated from the toxin-induced reduction in protein synthesis. whereas high toxin concentrations strongly reduced protein synthesis within 30 min, lower concentrations required longer times. the major part of the cell-bound toxin entered only after several hours. toxin entered cells after incubation at 25 degrees c but not at 20 degrees c, although toxin binding was the same at the two temperatures. increasing the kcl conce ... | 1983 | 6358031 |
| resistant shigella dysenteriae. | 1983 | 6140517 | |
| escherichia coli o157:h7 strains associated with haemorrhagic colitis in the united states produce a shigella dysenteriae 1 (shiga) like cytotoxin. | 1983 | 6132054 | |
| cholera-like enterotoxin produced by campylobacter jejuni. characterisation and clinical significance. | the presence and clinical significance of enterotoxins produced by campylobacter jejuni were investigated. the supernatant of a prototype virulent strain grown in supplemented medium induced intraluminal fluid secretion in rat ileal loop but not in rabbit ileal loop or the infant mouse assay. it induced elongation and increased intracellular cyclic amp levels in chinese hamster ovary cells. toxin activity was blocked by cholera antitoxin and was destroyed by heat and high or low ph; its molecula ... | 1983 | 6135079 |
| purification of shigella dysenteriae 1 (shiga)-like toxin from escherichia coli o157:h7 strain associated with haemorrhagic colitis. | 1983 | 6136724 | |
| co-trimoxazole-resistant shigella dysenteriae type 1 outbreak in a family in bangladesh. | 1983 | 6137632 | |
| opening pandora's box. | 1983 | 264908 | |
| clinical and structural features and possible pathogenic mechanisms of dental fluorosis. | 1983 | 272716 |