Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| an outbreak of mayaro virus disease in belterra, brazil. i. clinical and virological findings. | an outbreak of human illness caused by mayaro (may) virus occurred in belterra, pará, brazil in the first half of 1978. a total of 55 cases were confirmed, 43 by virus isolation and serology, and 12 by serology alone. the disease in belterra presented as a distinct clinical syndrome characterized by fever, arthralgia and exanthema. no fatalities could be attributed to may virus infection. arthralgia, accompanied by joint edema in 20% of cases, was a very prominent sign which caused temporary inc ... | 1981 | 6266263 |
| isolation of mayaro virus from a migrating bird captured in louisiana in 1967. | 1974 | 4418030 | |
| further studies on the influence of steroids on viral infection in mice. | certain steroids have been reported to enhance experimental viral infections, whereas others have little or no effect. interference with the interferon system has been suggested as a possible mechanism for the viral infection-enhancing (vie) activity of hormones. in the present study, steroids (prednisolone, progesterone, testosterone) which had no effect on mm virus infection demonstrated vie activity against mayaro virus infection. it is suggested that the vie activity of a hormone may be depe ... | 1973 | 4353541 |
| synthesis of virus macromolecules in l-929 cells infected with mayaro virus. | 1970 | 4991746 | |
| the morphology of mayaro virus. | 1963 | 14062906 | |
| mayaro virus isolated from a trinidadian mosquito, mansonia venezuelensis. | a strain of mayaro virus has been isolated in trinidad from the mosquito mansonia venezuelensis. this is the first record of isolation of this agent from naturally infected mosquitoes, caught in the wild. | 1960 | 13792204 |
| mayaro virus: a new human disease agent. i. relationship to other arbor viruses. | 1957 | 13487972 | |
| mayaro virus: a new human disease agent. ii. isolation from blood of patients in trinidad, b.w.i. | 1957 | 13487973 | |
| mayaro virus: a new human disease agent. iii. investigation of an epidemic of acute febrile illness on the river guama in pará, brazil, and isolation of mayaro virus as causative agent. | 1957 | 13487974 | |
| genome analysis of mayaro virus imported to germany from french guiana. | 0 | 24960052 | |
| approaches to the treatment of disease induced by chikungunya virus. | chikungunya virus, a re-emerging mosquito-borne alphavirus, causes fever, rash and persistent arthralgia/arthritis in humans. severe outbreaks have occurred resulting in infections of millions of people in southeast asia and africa. currently there are no antiviral drugs or vaccines for prevention and treatment of chikungunya infections. herein we report the current status of research on antiviral drugs and vaccines for chikungunya virus infections. | 0 | 24434329 |
| sindbis and middelburg old world alphaviruses associated with neurologic disease in horses, south africa. | old world alphaviruses were identified in 52 of 623 horses with febrile or neurologic disease in south africa. five of 8 sindbis virus infections were mild; 2 of 3 fatal cases involved co-infections. of 44 middelburg virus infections, 28 caused neurologic disease; 12 were fatal. middelburg virus likely has zoonotic potential. | 0 | 26583836 |
| factors shaping the adaptive landscape for arboviruses: implications for the emergence of disease. | many examples of the emergence or re-emergence of infectious diseases involve the adaptation of zoonotic viruses to new amplification hosts or to humans themselves. these include several instances of simple mutational adaptations, often to hosts closely related to the natural reservoirs. however, based on theoretical grounds, arthropod-borne viruses, or arboviruses, may face several challenges for adaptation to new hosts. here, we review recent findings regarding adaptive evolution of arboviruse ... | 0 | 23374123 |
| viral arthritis. | acute-onset arthritis is a common clinical problem facing both the general clinician and the rheumatologist. a viral aetiology is though to be responsible for approximately 1% of all cases of acute arthritis with a wide range of causal agents recognised. the epidemiology of acute viral arthritis continues to evolve, with some aetiologies, such as rubella, becoming less common due to vaccination, while some vector-borne viruses have become more widespread. a travel history therefore forms an impo ... | 0 | 27037381 |
| mayaro virus in child with acute febrile illness, haiti, 2015. | mayaro virus has been associated with small outbreaks in northern south america. we isolated this virus from a child with acute febrile illness in rural haiti, confirming its role as a cause of mosquitoborne illness in the caribbean region. the clinical presentation can mimic that of chikungunya, dengue, and zika virus infections. | 0 | 27767924 |
| picornavirus morphogenesis. | the picornaviridae represent a large family of small plus-strand rna viruses that cause a bewildering array of important human and animal diseases. morphogenesis is the least-understood step in the life cycle of these viruses, and this process is difficult to study because encapsidation is tightly coupled to genome translation and rna replication. although the basic steps of assembly have been known for some time, very few details are available about the mechanism and factors that regulate this ... | 0 | 25184560 |
| ilheus virus infection in human, bolivia. | 0 | 22377378 | |
| mayaro virus infection, amazon basin region, peru, 2010-2013. | during 2010-2013, we recruited 16 persons with confirmed mayaro virus infection in the peruvian amazon to prospectively follow clinical symptoms and serologic response over a 12-month period. mayaro virus infection caused long-term arthralgia in more than half, similar to reports of other arthritogenic alphaviruses. | 0 | 24210165 |
| zika virus outbreak, bahia, brazil. | 0 | 26401719 | |
| mayaro virus and dengue virus 1 and 4 natural infection in culicids from cuiabá, state of mato grosso, brazil. | this study aimed to verify the diversity of culicidae species and their frequency of infection with flaviviruses and alphaviruses in cuiabá, state of mato grosso, brazil. mosquitoes were captured with nasci aspirators and hand net in 200 census tracts, identified alive at species level and pooled in one-20 (11,090 mosquitoes, 14 species). female pools (n = 610) were subjected to multiplex seminested-reverse transcription-polymerase chain reaction (rt-pcr) for 11 flavivirus and five alphavirus. p ... | 0 | 26784852 |
| evaluation of commercially available serologic diagnostic tests for chikungunya virus. | chikungunya virus (chikv) is present or emerging in dengue virus-endemic areas. infections caused by these viruses share some common signs/symptoms, but prognosis, patient care, and persistent symptoms differ. thus, accurate diagnostic methods are essential for differentiating the infections. we evaluated 4 chikv serologic diagnostic tests, 2 of which showed poor sensitivity and specificity. | 0 | 25418184 |
| the virus as metabolic engineer. | recent genome-wide screens of host genetic requirements for viral infection have reemphasized the critical role of host metabolism in enabling the production of viral particles. in this review, we highlight the metabolic aspects of viral infection found in these studies, and focus on the opportunities these requirements present for metabolic engineers. in particular, the objectives and approaches that metabolic engineers use are readily comparable to the behaviors exhibited by viruses during inf ... | 0 | 20665642 |
| evolutionary and ecological characterization of mayaro virus strains isolated during an outbreak, venezuela, 2010. | in 2010, an outbreak of febrile illness with arthralgic manifestations was detected at la estación village, portuguesa state, venezuela. the etiologic agent was determined to be mayaro virus (mayv), a reemerging south american alphavirus. a total of 77 cases was reported and 19 were confirmed as seropositive. mayv was isolated from acute-phase serum samples from 6 symptomatic patients. we sequenced 27 complete genomes representing the full spectrum of mayv genetic diversity, which facilitated de ... | 0 | 26401714 |
| false-negative dengue cases. | 0 | 25923902 | |
| chikungunya virus infections among travellers returning to spain, 2008 to 2014. | since the first documented autochthonous transmission of chikungunya virus in the caribbean island of saint martin in 2013, the infection has been reported within the caribbean region as well as north, central and south america. the risk of autochthonous transmission of chikungunya virus becoming established in spain may be elevated due to the large numbers of travellers returning to spain from countries affected by the 2013 epidemic in the caribbean and south america, as well as the existence o ... | 0 | 27631156 |
| sustained elevated cytokine levels during recovery phase of mayaro virus infection. | 0 | 26981875 | |
| dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma. | targeting reprogrammed energy metabolism such as aerobic glycolysis is a potential strategy for cancer treatment. however, tumors exhibiting low-rate glycolysis or metabolic heterogeneity might be resistant to such treatment. we hypothesized that a therapeutic modality that drove cancer cells to high-rate glycolysis might sensitize cancer cells to interference directed against metabolic flux. in this study, we found that attenuated oncolytic measles virus edmonston strain (mv-edm) caused gliobla ... | 0 | 25575816 |