Publications

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anthelmintic efficiency of fenbendazole in equines.a single oral dose of fenbendazole (fbz) at 10mg/kg body mass was given to 5 donkeys. a further 5 donkeys were dosed with a medicated lick (1 mg fbz/g lick) until the oral consumption was 10mg/kg body mass. in both trials fbz was highly effective against adults of the following genera: cyathostomum, cylicocyelus, cylicostephanus, cylicodontophorus, poteriostomum, cabellonema, craterostomum and triodontophorus; similarly high efficiency was obtained against the following species: habronema majus, ...19807241490
a possible physiological uptake mechanism of methylmercury by the marine bloodworm (glycera dibranchiata). 19807357117
studies on the efficacy of fenbendazole used in a divided dosage regime against strongyle infections in ponies.the efficacy of a fenbendazole divided dose regime against immature stages of trichonema spp, strongylus vulgaris and strongylus edentatus was evaluated. a group of 8 naturally infected 30 to 36-month-old ponies was divided into 2 equal groups on the basis of previous treatment and faecal egg counts, one group being treated with 7.5 mg/kg bwt of fenbendazole daily for 5 days. this treatment regime removed 80 per cent of migrating s vulgaris larvae, 100 per cent of migrating s edentatus larvae an ...19807371614
evaluation of pyrantel pamoate, nitramisole and avermectin b1a against migrating strongylus vulgaris larvae.trials were conducted in ponies to evaluate the efficacy of pyrantel pamoate (strongid-t(r)) and two newer anthelmintics not yet commercially available, nitramisole and avermectin b(1)a, against migrating strongylus vulgaris larvae. ponies were removed from their mares within 24-48 hr after birth and reared in isolation, worm free. between six and 14 weeks of age they were infected with 2000 or 2500 infective s. vulgaris larvae. subsequently, they were monitored daily for clinical signs until th ...19807397601
equine verminous arteritis; efficiency and speed of larvicidal acitivty as influenced by dosage of albendazole.albendazole was effective in destroying strongylus vulgaris larvae in verminous lesions of the cranial mesenteric artery when administered as a 20% suspension by stomach tube to ponies. fifty mg/kg body weight administered twice a day for 2 days caused death and gradual disintegration of larvae over a period of 3 to 6 weeks with mild toxic signs appearing in 3 of 11 ponies. higher total doses of albendazole (50 mg/kg twice a day for 4 days and 25 mg/kg three times a day for 5 days) lead to more ...19807408495
clinical aspects of strongylus vulgaris infection in the horse. emphasis on diagnosis, chemotherapy, and prophylaxis. 1979399708
critical test evaluation of butamisole against gastrointestinal parasites of horses and ponies.a critical test was performed to evaluate the anthelmintic properties of an injectable butamisole formulation and to compare the efficiency with that of a commercially available piperazine-thiabendazole anthelmintic. the test was done in 10 horses and 15 ponies with naturally acquired parasitic infections. butamisole was administered at the dose level of 2.5 or 3.75 mg/kg of body weight by either subcutaneous or deep intramuscular injection. given at the dose level of 2.5 mg/kg, butamisole was h ...1979453676
critical anthelmintic trials in ponies with oxfendazole and caviphos and concomitant studies on the spontaneous elimination of small strongylids.the efficacy of the benzimidazole, oxfendazole, and the organophosphate, caviphos, against gastrointestinal parasites of ponies was evaluated by the critcial test method. oxfendazole (10 mg/kg of body weight) given in single oral doses was 100% effective against adult large strongylids (strongylus vulgaris, strongylus edentatus, and strongylus equinus), 99% effective against adult small strongylids, and 97% effective against 4th-stage small strongylids (genera identified in order of frequency: c ...1979475090
[verminous enteritis and thrombo-embolic colic in the horse. a description of 36 cases (author's transl)].based upon case reports from 36 cases of verminous thrombosis of arteria mesenterica cranialis--all of which were verified at necropsy--clinical symptoms, course and pathological lesions are described. seventy five per cent of the patients were under 3 years old, and 73% of the cases showed initial signs during the period july-december. salient clinical findings were, unthrifty appearance and emaciation, diarrhoea--observed in two thirds of the patients--and colic--observed in 50 per cent of the ...1979492971
benzimidazole resistance of equine stronygles--critical tests of six compounds against population b.critical tests were conducted on eight horses naturally infected with several species of large and small strongyles from population b. tested were six benzimidazoles, including thiabendazole (2 lots) (44 mg/kg of body weight); mebendazole (8.8 mg/kg); cambendazole (two formulations) (20 mg/kg); fenbendazole (10 mg/kg); oxibendazole (10 mg/kg); and oxfendazole (10 mg/kg). all compounds were administered by stomach tube except one of the two cambendazole formulations which was an intraoral paste. ...1979517836
the epidemiology of equine strongylosis in southern queensland. 3. seasonal variation in arterial populations of strongylus vulgaris, and the prevalence of some helminths.the anterior mesenteric arteries of 138 horses slaughtered in southern queensland were examined for the presence of s. vulgaris larvae. seasonal differences were noted in the size of arterial populations of this parasite, with higher mean monthly numbers of worms per horse occurring in winter. there was an equally high incidence of severe verminous arteritis during the winter months of june, july and august, compared to arteries examined during the warmer months, when there were smaller numbers ...1979518433
equine verminous arteritis. an arteriographic evaluation of the larvicidal activity of albendazole.albendazole was an effective larvicidal anthelmintic against the fourth stage strongylus vulgaris larvae as late as one month post-infection. the drug was administered at a dose rate of 25 mg/kg three times daily for 5 days. diarrhoea occurred in 3 of 4 foals treated and of these one died during belated intravenous therapy for dehydration. arteriography allowed for an in vivo assessment of the development and regression of lesions in infected-treated foals compared to the continued development o ...1979540630
anthelmintic efficiency of fenbendazole in equines.a single oral dose of fenbendazole (fbz) at 10 mg/kg body mass was given to 5 donkeys. a further 5 donkeys were dosed with a medicated lick (1 mg fbz/g lick) until the oral consumption was 10 mg/kg body mass. in both trials fbz was highly effective against adults of the following genera: cyathostomum, cylicocyclus, cylicostephanus, cylicodontophorus, poteriostomum, cabellonema, craterostomum and triodontophorus; similarly high efficiency was obtained against the following species: habronema maju ...1979553963
increase of immunoglobulin t concentration in ponies as a response to experimental infection with the nematode strongylus vulgaris. 197875703
critical tests of the anthelmintic febantel in the horse: activity of a paste formulation alone or with a trichlorfon paste.critical tests were carried out in 10 horses to evaluate the antiparasitic activity of febantel given alone or with trichlorfon. paste formulations were administered intraorally at dose levels of 6 mg of febantel (active ingredient)/kg and 35 mg of trichlorfon (active ingredient)/kg. in 5 tests with febantel alone, removal of 100% was recorded for mature or immature parascaris equorum from 2 infected horses. strongylus vulgaris from 4 infected horses, s edentatus from 5 infected horses, and matu ...1978697152
an evaluation of the efficacy of oxfendazole against the common nematode parasites of the horse.in a controlled trial in naturally-infected young ponies, oxfendazole administered orally at dose-rates of 10 mg per kg and 50 mg per kg resulted in complete elimination of trichostrongylus axei, parascaris equorum, oxyuris equi and adult strongylus vulgaris. also, all migrating strongylus edentatus larvae recovered from the subperitoneal tissues of the flank were found to be dead. minimum efficiencies of 99.8 per cent and 99.1 per cent were obtained against adult small strongyles (trichonema sp ...1978364817
the efficacy of fenbendazole in the control of immature strongyle infections in ponies.the efficacy of fenbendazole against immature stages of trichonema spp., strongylus vulgaris and strongylus edentatus was evaluated. naturally infected 6 to 12 month old ponies were given single, oral doses of 0, 15, 30 and 60 mg/kg of body weight. a dose response relationship was noted between increasing dose levels and efficiency against larval trichonemes and migrating stages of s. vulgaris and s. edentatus. dose levels of 30 mg/kg and higher removed 93 per cent of mucosal stages of trichonem ...1977560964
diagnosis and treatment of "verminous aneurysm" formation in the horse.the clinical manifestations, diagnosis and differential diagnosis of "verminous aneurysm" formation at the root of the cranial mesenteric artery and coeliac artery resulting from strongylus vulgaris larvae migration are described. forty-nine of 57 cases were successfully treated with low molecular weight dextran (dextran 70).1977579006
clinical response of pony foals experimentally infected with strongylus vulgaris. 1977596704
arteriography in ponies with strongylus vulgaris arteritis.radiographs of the aorta and abdominal arteries were obtained from a normal anesthetized pony following catheterization of a femoral artery for nonselective, semiselective or selective arteriography. the arteries had smooth borders and regular diameters and the branches of the cranial mesenteric artery could be followed distally on the angiogram through to the smaller branches proximal to the bowel wall. following arteriography, the pony walked normally and there were minimal alterations of the ...1977861832
an evaluation of ethyl-6-ethoxybenzothiazole-2-carbamate (sch 18099) for anthelmintic activity in domestic animals.ethyl-6-ethoxybenzothiazole-2-carbamate (sch 18099) was evaluated for efficacy against natural helminth infections in ponies, pigs, lambs and chickens. sixteen critical trials were conducted in ponies at dosages of 15 to 150 mg/kg. at 15 mg/kg, efficacy against adult and larval oxyuris equi was 100% and 91% and against small strongyles it was 98%. efficacy levels were 95% against strongylus vulgaris and s. edentatus at the 20 mg/kg dosage. in two trials at 100 mg/kg efficacy against parascaris e ...1977864223
critical tests of the antiparasitic activity of thiabendazole and trichlorfon sequentially administered to horses via stomach tube.thirteen critical tests were conducted in horses naturally infected with helminths and bots. single doses of thiabendazole (44 mg/kg of body weight) and trichlorfon (40 mg/kg of body weight) powder formulations were administered as suspensions sequentially given via stomach tube to evaluate the efficacy of the combination against the large parasites of horses. parasite removal efficacies were 100% against 2nd instar gasterophilus intestinalis and 2nd and 3rd instar gasterophilus nasalis and 82 t ...1977879569
critical anthelmintic trials in ponies with four benzimidazoles: mebendazole, cambendazole, fenbendazole, and albendazole.the comparative efficacy of four benzimidazoles against gastrointestinal parasites of ponies was evaluated by the critical test method. mebendazole (8.8 mg/kg), cambendazole (20 mg/kg), fenbendazole (5 mg/kg), and albendazole (2.5 and 5 mg/kg) given in single oral doses were highly effective against adult large strongylids (strongylus vulgaris, s. endentatus, s. equinus) and adult small strongylids (genera identified in order of frequency: cylicostephanus, cylicocyclus, cyathostomum, triodontoph ...1977886410
critical tests of anthelmintic activity of a paste formulation of thiabendazole in horses.critical tests of the activity on large strongyles, ascarids, mature pinworms, and bots were carried out in 11 horses intraorally treated with a paste formulation of thiabendazole. the dose level of 44 mg/kg was administered to 3 horses, and the dose level of 88 mg/kg to 8 horses. removals of strongylus vulgaris and mature oxyuris equi were 100% at the 2 dose levels, and efficacy against strongylus edentatus varied from 95 to 99% and 89 to 100% for the 44- and the 88-mg/kg dose levels, respectiv ...1976937790
eimeria leuckarti infection in foals.this is the first report on eimeria leuckarti infection in foals in japan. seven thoroughbred or angloarabian foals 2 to 7 months of age raised in the hidaka district, hokkaido, were infected with e. leuckarti. they died of severe alterations caused by the larval migration of strongylus vulgaris, and were examined over a period from 1970 to 1973. protozoa of this species were observed in the small intestine in all the foals. they were found mostly in vacuoles of the cytoplasm of monoclear cells ...1976950993
strongylus vulgaris in the horse: a review. 1976779947
heterogeneity and oxygen equilibria of haemoglobin from the bloodworm glycera gigantea. 19761248215
critical tests and safety studies on trichlorfon as an antiparasitic agent in the horse.three series of critical tests were completed on a combined total of 46 horses to determine the efficacy of single doses of trichlorfon against bots, ascarids, pinworms, and large strongyles. different formulations of trichlorfon were administered by tubing intragastrically, mixing with the daily grain ration, injecting intramuscularly, or pouring on the back at dose rates between 20 and 100 mg/kg. administration by feeding tended to be more efficacious for removal of bots and less toxic to the ...19761259212
critical tests of suspension, paste, and pellet formulations of cambendazole in the horse.three formulations of cambendazole were evaluated for anthelmintic activity by critical testing method in 21 horses. cambendazole suspension was administered via stomach tube at the dose rate of 10 mg/kg to 3 horses and at the dose rate of 20 mg/kg to 3 horses. cambendazole paste was given intraorally to 8 horses, and the pellet formulation was fed to 7 horses at the dose rate of 20 mg/kg. anthelmintic activity of cambendazole was similar for all dose rates and formulations. gasterophilus intest ...1975123710
osmotic responses of the bloodworm glycera dibranchiata ehlers: a graphical approach to the analysis of weight regulation. 1975240565
[granulomatous lymphadenitis in a horse due to 4th stage larvae of strongylus vulgaris]. 19751115742
the pathogenesis of single experimental infections with strongylus vulgaris in foals.the clinical signs, pathology and clinical pathology associated with single experimental infections of strongylus vulgaris in worm-free pony foals are described. the major clinical signs which became apparent in the infected foals during the first three weeks were pyrexia, anorexia, dullness and abdominal pain. within the first two weeks of infection lesions were confined to the intestine and terminal branches of the intestinal arteries and consisted of mucosal, submucosal and serosal haemorrhag ...19751118668
studies on the epidemiology of strongylus vulgaris infection of the horse. 19751140880
strongylus vulgaris-the horse killer. 19751143279
diarrhoea in horses associated with ulceration of the colon and caecum resulting from s vulgaris larval migration.the clinical manifestations of a diarrhoeic syndrome of horses with ulceration of the mucosae of the colon and caecum are described. patients could be divided into three groups according to their presenting symptoms and the disease is probably caused by the thrombo-embolism associated with migrating larvae of strongylus vulgaris. the differential diagnosis, prognosis and treatment are outlined with particular reference to the use of antithrombotic agents.19751162877
the pathogenesis and control of strongyle infection in the horse.the migratory route of infective strongylus vulgaris larvae was determined: penetration of small and large intestine into the lumina of submucosal arteries, migration up the arterial tree, reaching the cranial mesenteric site by three weeks, where the larvae develop to the mature 4th stage. after 3-4 months they exsheath and the young adults migrate down the arteries towards the intestines, to the limit of arterial narrowing, from where they rupture from nodules into the lumen of the intestine. ...19751177246
[arterial repair after mechanical injury by migrating fourth-stage larvae of strongylus vulgaris in the horse (a light and electron microscopic study) (author's transl)].introduction: migrating fourth-stage larvae of strongylus vulgaris, a parasite of equines, damage the intima of the anterior mesenteric artery and its larger branches and induce thrombus formation on the injured sites. as the time of larval passage through each of these branches has been exactly determined in earlier experiments, the aim of the present studies is to contribute to a more complete understanding of repair mechanisms in the process of time after thrombotic vascular injuries. materia ...19751180809
oxibendazole: critical anthelmintic trials in equids.the efficacy of oxibendazole against gastrointestinal parasites of horses was evaluated by the critical test method. naturally infected ponies of various ages were given single oral doses of 5, 10, or 15 mg-kg of bodyweight. the drug was highly effective against adult large strongylids (strongylus vulgaris, s edentatus, s equins), adult small strongylids (especially species of the genera cylicostephanus, cylicocyclus, cyaathostomum, and triodontophorus), and adult and larval stages of the large ...19751216434
host response to experimentally induced infections of strongylus vulgaris in parasite-free and naturally infected ponies. 19744417305
verminous encephalitis of horses: experimental induction with strongylus vulgaris larvae. 19744433067
strongylus vulgaris infection in the horse. 19744446282
further observations on the maintenance of a monospecific infection of strongylus vulgaris in the horse. 19734721941
the kikuchi--enigk model of strongylus vulgaris migrations in the horse. 19734574177
fine structure of erythrocytes of the common bloodworm glycera dibranchiata. 19724649372
the role of ultrastructure and physiological differentiation of epithelia in amino acid uptake by the bloodworm, glycera. 19725021125
the amino acid sequence of the monomeric hemoglobin component from the bloodworm, glyat liver. 19725063466
the life cycle of strongylus vulgaris in the horse. 19725072578
the structures of lamprey and bloodworm hemoglobins in relation to their evolution and function. 19724508148
the isolation and maintenance of a monospecific infection of strongylus vulgaris in the horse. 19715542322
heterogeneity of the hemoglobin from the common bloodworm glycera dibranchiata. 19715547700
obliquely striated muscle : iv. sarcoplasmic reticulum, contractile apparatus, and endomysium of the body muscle of a polychaete, glycera, in relation to its speed.body muscle cells of the bloodworm glycera, a polychaete annelid, were studied by electron microscopy and compared with muscle cells of the more slowly acting nematode ascaris, which have been described previously. both muscles are obliquely striated. the predominant type of bloodworm fiber is characterized by a prominent transversely oriented sarcoplasmic reticulum with numerous dyads at the surface of each cell. thick myofilaments are approximately 3 micro long and overlap along approximately ...196819866720
studies on pathological lesions due to strongylus vulgaris infection in an indian pony. 19666009405
[spinal nematodosis in the horse caused by strongylus vulgaris]. 19655895489
[on morphology of strongylus vulgaris (nematoda)]. 195214951659
[further studies on the biology of strongylus vulgaris (nematodes) in the host]. 195114837165
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