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development of the adult pelage in normal and hormone-injected spiny mice (acomys cahirinus).the dorsal pelage of the adult egyptian spiny mouse (acomys cahirinus) consists primarily of coarse brittle spines which differ from those of the juvenile pelage. the development of the adult pelage in juvenile spiny mice was examined in normal and estradiol- or testosterone-injected animals. females complete the development of their adult pelage significantly faster than males. both estradiol and testosterone injections speed pelage development in males. testosterone causes a significant delay ...19817338723
comparison of insulin secretion by the isolated perfused pancreas and perifused islets of the spiny mouse (acomys cahirinus).the dynamics of glucose-stimulated insulin release were studied in the perfused pancreas and in isolated perifused islets of spiny mice. the pattern of insulin release induced by an increase of the glucose concentration from 2.8 mm to 16.7 mm was different in the two preparations. in the perfused pancreas there was an early insulin release contrasting with an absence of the early response in isolated islets. the later insulin release response (5 min to 30 min) was present and similar in both pre ...19817020305
delayed or biphasic glucose-induced insulin secretion of pancreatic islets isolated from spiny mice (acomys cahirinus) : relation to age of animals.the dynamics of insulin release from spiny mouse perifused pancreatic islets was investigated. in agreement with earlier studies we found no initial (0-10 min) insulin secretion in response to glucose in islets prepared from mice up to 35 weeks of age. the islets of animals older than 40 weeks, however, were characterized by greater insulin content, and a restored typical biphasic insulin secretion profile. the results suggest that immediate glucose response is modified by environmental or other ...19806989661
accumulation of pancreas-specific products during organogenesis of acomys cahirinus. 19806997134
maternal behavior and the milk ejection reflex in a precocial murid (acomys cahirinus). 19807362595
effect of diet-induced obesity on glucose and insulin tolerance of a rodent with a low insulin response (acomys cahirinus). 1979446935
glucose production by the perfused liver of the spiny mouse (acomys cahirinus): sensitivity to glucagon and insulin.hepatic glucose production and its responses to glucagon and insulin were studied in perfused livers obtained from spiny mice (acomys cahirinus)--rodents characterized by normoglycemia, decreased glucose tolerance and decreased insulin secretion--and from swiss albino mice. the dose-response characteristics of glucagon-induced hepatic glucose output were similar in spiny and albino mice. however, maximally stimulated glucose production were significantly lower in the spiny mouse. furthermore, th ...1979468520
helminths of birds and mammals of israel. viii.- skrjabinocapillaria rodentium n. sp. (nematoda capillariidae) from gerbillid and murid rodents.skrjabinocapillaria rodentium n.sp., found in the stomach of meriones crassus, gerbillus pyramidum, g. gerbillus, g. dasyurus and acomys cahirinus, is described. it differs from the other two species in the genus, s. bakeri and s. eubursata, mainly in being larger, having a larger number of stichocytes and having a cephalic influation in the female and not in the male.1979485042
the reproductive tract of the male spiny mouse (acomys cahirinus) and coagulation studies with other species.the testes of the spiny mice showed asymmetry, the left being significantly heavier than the right (p = 0.025). histological studies indicated that spermatozoa were first present in the testes of animals 35--45 days of age but the maturation of the accessory glands, especially the lateral prostates and coagulating glands, occurred later. the highest fructose concentration in the adult was in the lateral prostates (126.97 +/- 22.23 mg fructose/100 g, n = 5) and coagulating glands (99.38 +/- 17.65 ...1979513000
temporal parameters of responsiveness to maternal pheromone in acomys cahirinus. 1978740774
responses of acomys cahirinus pups to chemical cues produced by a foster species. 1977901356
significance of anomalous thermoregulation in the pre-diabetic spiny mouse (acomys cahirinus): oxygen consumption and temperature regulation.in keeping with studies of other desert rodents, the potentially diabetic spiny mouse has been demonstrated to have a very low basal metabolic rate, disproportionate to its body weight. the maintenance of a lower body temperature in response to high environmental temperatures and a lack of increase in metabolic rate in response to cooling have also been demonstrated. assessments of "mechanical efficiency" have shown that spiny mice carry a potential selective advantage under fasting conditions. ...1977603467
significance of anomalous thermoregulation in the pre-diabetic spiny mouse (acomys cahirinus): cold tolerance: blood glucose and food consumption responses to environmental heat.decreased cold tolerance, reduced food requirement for body weight maintenance and comparative resistance to the hypoglycaemic effect of fasting in high ambient temperatures have been demonstrated in the spiny mouse. these phenomena could be related to anomalous spiny mouse thermoregulation, a phenomenon which is common in desert rodents and is simulated by mutant and artificially diabetic rodent species. the data can be interpreted as showing evidence for a survival advantage of genotypes with ...1977603468
dietary-dependent cross-species similarities in maternal chemical cues.acomys cahirinus pups preferred chemical cues from conspecific lactating females maintained on the maternal diet as compared to such cues from females fed an unfamiliar diet. likewise, chemical cues from maternal diet mus musculus were preferred over those from unfamiliar diet conspecific females. thus, the production of maternal chemical stimuli may be basically similar in acomys and mus, with maternal diet being more critical than genetically programmed species-specific characteristics in dete ...197711803674
breeding and reproduction of fifteen wild rodents maintained as laboratory colonies.data on reproduction and production were presented for laboratory colonies of microtus pennsylvanicus tananaensis, m oeconomus macfarlani, m o operarius, m mirurus, m abbreviatus, lemmus lemmus, l sibiricus trimucronatus, dicrostonyx stevensoni, clethrionomys rutilus, peromyscus maniculatus borealis, p m bairdii, baiomys taylori, calomys ducilla, c callosus, acomys cahirinus. litter size varied from 2.0 in a cahirinus to 5.5 in c callosus. infant (neonatal) and juvenile losses through the end of ...1976775192
proinsulin synthesis in islets of langerhans from spiny mice (acomys cahirinus). comparison with rats and mice.proinsulin synthesis in response to different concentrations of glucose has been studied in islets of langerhans of acomys, rat and mouse. the response to increased glucose was small in acomys when compared with rat or mouse. the time course of the effect of glucose on proinsulin synthesis was also studied in sequential 15 min periods up to 60 min. with 5.5 mm glucose the rate of 3h-leucine incorporation for acomys islets were greater over the periods 15-30, 30-45 and 45-60 min after the additio ...1976789163
maternal pheromone in the spiny mouse (acomys cahirinus). 1976944929
breeding and fertility of the egyptian spiny mouse, acomys cahirinus: effect of different environments.2 years experience with acomys in one laboratory confirmed the slow breeding rate found by other workers. on moving the animals to another laboratory there was a 2-5 fold increase in breeding rate. the most likely explanation of this change was the presence of copper in the drinking water at the 1st laboratory, due to the use of copper water pipes. the data relating to maintenance and breeding of acomys for 2 years at the 2nd laboratory were analyzed to provide a more representative picture of t ...19761256010
a sensitive period for the development of olfactory preference in acomys cahirinus. 1976996137
the verification of neurones in the pancreas of spiny mice (acomys cahirinus).the statement that up to now no neural elements could be identified in the islets of langerhans with the aid of electron microscopy led us to reinvestigate this question of innervation of the pancreas in spiny mice using light microscopy. single nerve cells as well as nerve fibre bundles could be found in the interlobular connective tissue of the pancreas. by constrast, we could observe neither nerve cells nor nerve fibres in the islets of langerhans. extrainsular neuroinsular complexes could no ...1976773639
sex-differences in the agonistic behavior of spiny-mice (acomys cahirinus).observations of 8 groups each containing three adult spiny mice (acomys cahirinus) revealed that instances of chasing and physical displacement were quite common, while fighting and biting were rarely observed. the relationships between the most frequent behavioral categories were presented in a correlation matrix. in a second study, females tested in their home cages were dominant over males. in the males' home cages, however, no differences in the frequency of female vs. male aggression were o ...1976944978
a primacy effect for olfactory imprinting in spiny mice (acomys cahirinus. 19751212161
hyperlipidemia and hepatic hyperlipogenesis in spiny mice (acomys cahirinus) on carbohydrate diets: relationship to peripheral underresponsiveness and low insulin release. 19751167180
[preliminary study of the karyotype of acomys airensis (rodentia, muridae)]. 19751225681
[the evidence of biogenic amines with reinecke-salt as a new principle of evidence of substances in the ultrahistochemistry (author's transl)].reinecke-salt (ammonium tetracyanato diamine chromate) is known as amine precipitating reagens in applied chemistry. its amine precipitates can be demonstrated in electron micrographes. the amine reineckates are unable to diffuse and difficult to dissolve. depending from that they are localized in the cells. from our findings received in the boundary layer between adrenal cortex and adrenal medulla, we conclude that there are no non-specific precipitations with other cell components caused by re ...1975813480
retinal capillary basement membrane thickness in spiny mice (acomys cahirinus) with induced and spontaneous diabetes.basement membrane thickness was measured in two groups of spiny mice (acomys cahirinus): one with spontaneous diabetes, the other with streptozotocin-induced diabetes. a statistical analysis of the morphometric results of the two groups showed a significant basement membrane thickening in the group with induced diabetes when compared to the spontaneously diabetic group.1975124711
defective insulin secretion in the spiny mouse (acomys cahirinus). possible value in the study of the pathophysiology of diabetes. 1975169217
an apparent abnormaltiy of the b-cell microtubular system in spiny mice (acomys cahirinus).the pancreatic b-cell contains microtubules, which are thought to participate in the process of insulin release. in order to disclose a possible abnormaltiy of this b-cell microtubular system in animals with islet dysfunction, isolated islets from normal rats and mice, as well as from diabetic mutant mice (dbm mice) and from spiny mice (acomys cahirinus) were incubated in the presence of vincristine, which causes the precipitation of the microtubular protein into paracrystalline deposits. ultras ...19751095441
defective early phase insulin release in perifused isolated pancreatic islets of spiny mice (acomys cahirinus).in order to characterize pancreatic beta cell function in geneva bred spiny mice (acomys cahirinus), the dynamics of immunoreactive insulin release were examined during perifusion of pancreatic islets isolated from normoglycemic acomys. the initial insulin response of acomys was slow: no clear-cut early (1 to 10 min) peak of insulin release was observed when glucose in the perifusion medium was abruptly raised from 2.8 mm to concentrations as high as 56 mm. this was true for islets of either you ...1975171800
insulin secretion in the spiny mouse (acomys cahirinus). dose and time kinetic studies with glucose in vivo and in vitro.plasma insulin responses to the intravenous injection of glucose in the doses of 0.5, 1.5, and 3.0 gm./kg. were compared in spiny mice (acomys cahirinus) and weight-matched swiss albino mice. the mean early (two-minute) plasma insulin response was significantly lower in acomys at all doses of glucose injected; whereas, at later times (5, 15, and 30 minutes), differences in plasma insulin concentrations in the two species of mice were smaller or nonexistent. plasma glucose clearance was significa ...19751104397
ultrastructure of the oocytes of the egyptian sping mouse (acomys cahirinus).the oocytes of types 2, 3, 4 and 5 follicles from the normal spiny mouse were examined withe the electron microsome. multiple juxtanuclear golgi bodies, mitochondria associated with flattened granular endoplasmic reticulum, and large nucleus are the main features of the type 2 follicle oocyte. the numbers of mitochondria and golgi apparati increase significantly at later stages. small mitochondrial aggregates lacking "intermitochondrial cement" are seen in the ooplasm of types 3, 4 and 5 follicl ...19751171638
metabolic adaptation of spiny mice (acomys cahirinus) transferred from the desert to laboratory diets. 19744370735
evidence for decreased sensitivity to glucose of isolated islets from spiny mice. (acomys cahirinus). 19744375063
[electron microscope detection of biogenic amines in the medulla of the adrenal gland of the normoglycemic spiny mouse (acomys cahirinus)].by means of a modification of the reinecke salt method already described, characteristical amine containing granules have been demonstrated in the parenchymal cells of the adrenal medulla in normoglycemic spiny mice. by this method two types of granules have been discerned according to their different contrasts. the advantages of the modification method are discussed.19744377491
the effect of dietary sucrose on plasma lipids and on the liver of the spiny mouse (acomys cahirinus). 19744419533
recent advances in mechanism of causation of diabetes mellitus in man and acomys cahirinus. 19744858609
olfactory imprinting resulting from brief exposure in acomys cahirinus. 19744414896
effects of previous exposure on olfactory discrimination in acomys cahirinus. 19744833517
androgen biosynthesis by testicular tissue of the desert rodents, acomys cahirinus and gerbillus dasyurus. 19734737075
seasonal observations on the cairo spiny mouse, acomys cahirinus (e. geoffroy, st. hilaire, 1803) and its fleas in egypt. 19734804345
haemoglobin of the spiny mouse (acomys cahirinus) (starch gel electrophoresis, chromatographic fractionation). 19724636757
[autofluorescent granules in the ependyma of the recessus inframamillaris of the yellow spiny mouse (acomys cahirinus dimidiatus)]. 19724339918
isolation and partial structural analysis of insulin from mouse (mus musculus) and spiny mouse (acomys cahirinus). 19725028210
defective immunoreative insulin secretion in the acomys cahirinus. 19724343799
hyperlipidemia and impaired glucose tolerance in acomys cahirinus maintained on synthetic carbohydrate diets. 19725055380
adaptive responses in enzyme activities of israeli spiny mice (acomys cahirinus). 19725041252
[obesity and diabetes mellitus in acomys cahirinus]. 19715145545
[effect of age on the avoidance conditioning of acomys cahirinus (desmarest) (rodents, muridae)]. 19715001914
insulin of spiny mice (acomys cahirinus)--partial characterization and evidence for two insulins. 19715540066
[spontaneous diabetes in a new spiny mice strain, acomys cahirinus cahirinus(desmarest 1819)]. 19715114353
testosterone biosynthesis in the desert mouse, acomys cahirinus. 19714399441
[the autonomous nervous system and the b-cell: metabolic and morphological observations made in spiny mice (acomys cahirinus) and in cultured fetal rat pancreas]. 19704919942
interstitial nephritis in the spiny mouse (acomys cahirinus) associated with klossiella sp. infection. 19705005922
the kidney of spiny mice (acomys cahirinus): electron microscopy of glomerular changes associated with ageing and tubular glycogen accumulation during hyperglycemia. 19705432358
metabolic state, pancreatic insulin content and b-cell morphology of normoglycemie spiny mice (acomys cahirinus): indications for an impairment of insulin secretion. 19704914669
studies in spiny mice (acomys cahirinus): metabolic state and pancreatic insulin release in vitro. 19695407070
[differences in the white blood picture and blood glucose concentration of fed and starving spiny mice (acomys cahirinus, desmarest, 1819)]. 19695346728
helminthic infection of cairo spiny mouse. acomys cahirinus (e. geoffroy, st. hilaire, 1803) in u.a.r. 19695393691
[on the cerebralization of the nest-escaping acomys (cahirinus) minous (bate, 1906) in comparison with the nest-dwelling (albino mouse, apodemus sylvaticus (linnaeus, 1758) and albino rat). ii. morphology and allometry of postnatal brain development of acomys (cahirinus) minous, of the albino mouse, and of the albino rat]. 19685719048
a breeding program for spontaneously diabetic experimental animals: psammomys obesus (sand rat) and acomys cahirinus (spiny mouse). 19684233365
[morphological and physiological lesions in the complex syndrome of spiny mice (acomys cahirinus)]. 19684917933
[the implantation time and the effect of lactation on it in acomys cahirinus dimidiatus]. 19675583113
[obesity and diabetes mellitus in acomys cahirinus]. 19675583112
ultrastructural studies of the hyperplastic islets of langerhans of spiny mice (acomys cahirinus) before and during the development of hyperglycemia. 19674907140
[the myelogenesis of a nidifugious type (acomys (cahirinus) minous, bate 1906) in comparison to a nidicolous type (albino mouse)]. 19676053711
acanthocephala of the genus moniliformis from rodents of egypt with the description of a new species from the egyptian spiny mouse (acomys cahirinus). 19676066757
obesity and diabetes mellitus with striking congenital hyperplasia of the islets of langerhans in spiny mice (acomys cahirinus) : i. histological findings and preliminary metabolic observations.spiny mice (acomys) are a group of small rodents indigenous to the eastern mediterranean and africa. the acomys cahirinus strain reported on here is indigenous to israel. the strain is characterized by striking and congenital hyperplasia of the islets of langerhans, primarily of the beta cells. the endocrine tissue contributes up to 15 per cent of the pancreatic mass in adults, up to 25 per cent in the newborn. pancreatic insulin content may be as high as 100 units per gram wet weight. when feda ...196624173297
[intraspecific and intraindividual chromosomal polymorphism in acomys minous bate (mammalia--rodentia--muridae). cytological study of acomys minous male x acomys cahirinus female hybrids. the mechanism of centric fusions]. 196314096525
the behaviour of plasmodium berghei and plasmodium vinckei in the spiny mouse acomys cahirinus. 196114448536
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