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partial recessive ifn-?r1 deficiency: genetic, immunological and clinical features of 14 patients from 11 kindreds.we report a series of 14 patients from 11 kindreds with recessive partial (rp)-interferon (ifn)-?r1 deficiency. the i87t mutation was found in nine homozygous patients from chile, portugal and poland, and the v63g mutation was found in five homozygous patients from the canary islands. founder effects accounted for the recurrence of both mutations. the most recent common ancestors of the patients with the i87t and v63g mutations probably lived 1600 (875-2950) and 500 (200-1275) years ago, respect ...201121266457
sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis.ultraviolet (uv) radiation has immunosuppressive effects and heliotherapy is a well-described treatment modality for psoriasis.201121271993
polymorphisms of glutathione s-transferase µ and ?, mdr1 and vegf genes as risk factors of bladder cancer: a case-control study.objective:: the present study was aimed at examining the local distribution of gstm1, gstt1, mdr1, and vegf gene polymorphisms as possible risk factors contributing to the development of bladder cancer among the population from canary islands, spain. materials and methods:: the genotypes were determined by pcr-based methods in a hospital-based case-control study consisting of 119 cases and 110 controls. the socio-demographic and clinicopathologic data were collected, including the smoking habits ...201121292509
the canary is alive and singing: birds continue to provide invaluable information about our changing environment. 201121184578
the analysis of groel gene in salmonella enterica subspecies enterica serovar typhimurium isolated from avians by pcr-restriction fragment length polymorphism method.salmonella enterica subspecies enterica serovar typhimurium causes food-borne outbreaks and systemic diseases in humans and animals. groel gene (also known as mopa gene in s. typhimurium), possessing conserved sequence, plays an important role in invasion of bacteria. the purpose of present study was to identify the polymorphism of groel gene among different avians in different regions by pcr-rflp method. fifty two s. typhimurium isolates (broiler (n = 13), layer (n = 12), duck (n = 5), goose (n ...201121312060
phylogeography of the atlanto-mediterranean sea cucumber holothuria (holothuria) mammata: the combined effects of historical processes and current oceanographical pattern.we assessed the genetic structure of populations of the widely distributed sea cucumber holothuria (holothuria) mammata grube, 1840, and investigated the effects of marine barriers to gene flow and historical processes. several potential genetic breaks were considered, which would separate the atlantic and mediterranean basins, the isolated macaronesian islands from the other locations analysed, and the western mediterranean and aegean sea (eastern mediterranean). we analysed mitochondrial 16s a ...201121463375
north african influences and potential bias in case-control association studies in the spanish population.despite the limited genetic heterogeneity of spanish populations, substantial evidences support that historical african influences have not affected them uniformly. accounting for such population differences might be essential to reduce spurious results in association studies of genetic factors with disease. using ancestry informative markers (aims), we aimed to measure the african influences in spanish populations and to explore whether these might introduce statistical bias in population-based ...201121479138
depth profile of (236)u/(238)u in soil samples in la palma, canary islands.the vertical distribution of the (236)u/(238)u isotopic ratio was investigated in soil samples from three different locations on la palma (one of the seven canary islands, spain). additionally the (240)pu/(239)pu atomic ratio, as it is a well establish tool for the source identification, was determined. the radiochemical procedure consisted of a u separation step by extraction chromatography using uteva(®) resin (eichrom technologies, inc.). afterwards pu was separated from th and np by anion ex ...201121481502
exercise tiger: assessing the bcm impact of the 2012 olympics on canary wharf.in this paper, collective corporate resilience is studied to see how a culture of sharing information and planning may assist other business communities to prepare for future events. the london 2012 summer olympic games will see huge opportunity for businesses in london, and across europe, but not without cost. canary wharf lies in the heart of london's docklands and less than three miles from the olympic park at stratford. purpose-built as a business district, it accommodates a working populati ...201121482513
chestnut cultivar diversification process in the iberian peninsula, canary islands, and azores.this is a large-scale molecular study based on simple sequence repeat (ssr) loci of the diversification process in chestnut cultivars from portugal and spain, from the northern iberian peninsula to the canary islands and the azores. a total of 593 grafted chestnut trees (castanea sativa mill.) were analysed with 10 ssrs: 292 from portugal and 301 from spain. some of the trees studied were more than 300 years old. accessions were analysed using a model-based bayesian procedure to assess the geogr ...201121491973
culture-induced chromosome abnormalities: the canary in the mine. 201121493156
poxvirus infection in stone curlews in the canary islands. 201121493519
benzoxacystol, a benzoxazine-type enzyme inhibitor from the deep-sea strain streptomyces sp. ntk 935.benzoxacystol, a new 1,4-benzoxazine-type metabolite, was produced by strain ntk 935, a marine member of the streptomyces griseus 16s rrna clade, isolated from deep-sea sediment collected from the canary basin. the structure of benzoxacystol was determined by mass spectrometry, nmr experiments and x-ray analysis. the compound showed an inhibitory activity against the enzyme glycogen synthase kinase 3β and a weak antiproliferative activity against mouse fibroblast cells.the journal of antibiotics ...201121505471
mapping unexplored genomes ii: genetic architecture of species differences in the woody sonchus alliance (asteraceae) in the macaronesian islands.despite numerous, well-documented evolutionary histories of plant groups which underwent rapid radiation in various oceanic archipelagos, very little is known about the genetic basis of species differences and adaptive radiation. this paper represents the first such study in the macaronesian islands using non-model endemic plants, the woody sonchus alliance. here i inferred the genetic basis of species differences between two canary island endemics, the herbaceous perennial, shade tolerant lactu ...201121505946
trypanosoma culicavium sp. nov., an avian trypanosome transmitted by culex mosquitoes.a new avian trypanosome, trypanosoma culicavium sp. nov., isolated from culex mosquitoes, is described on the basis of naturally and experimentally infected vectors and bird hosts, localization in the vector, morphological characters and molecular data. this study provides the first comprehensive description of a trypanosome species transmitted by mosquitoes, in which parasites form plugs and rosettes on the stomodeal valve. trypanosomes occurred as long epimastigotes and short trypomastigotes i ...201121515704
new bicyclotridecane c(15) nonterpenoid bromoallenes from laurencia marilzae.nonterpenoid bromoallenes possessing a novel skeleton that incorporates an unprecedented [5.5.1]bicyclotridecane ring system, marilzabicycloallenes a-d (1-4), were isolated from specimens of laurencia marilzae collected on the canary islands. the framework of these metabolites strongly reinforces braddock's hypothesis concerning the biosynthesis via electrophilic bromination of the obtusallene family.201121517101
characteristic phenolic composition of single-cultivar red wines of the canary islands (spain).the detailed phenolic composition of five single-cultivar (baboso negro, listán negro, negramoll, tintilla, and vijariego negro) young and aged (vintages 2005-2009) red wines of the canary islands has been determined by hplc-dad-esi-ms(n). despite the total monomeric anthocyanin content decreasing for older wines in each set of single-cultivar wines, the corresponding anthocyanin profiles remained almost unchanged. although all wine anthocyanin profiles were dominated by malvidin 3-glucoside, t ...201121548631
high prevalence of hypovitaminosis d in medical students in gran canaria. canary islands (spain).background: vitamin d deficiency has been described in many diseases and indeed in the general population. however fewer reports have been published in young and healthy people. vitamin d deficiency should not be found in medical students of the canary islands, because they have all the resources to avoid it. objective: to estimate the prevalence of vitamin d deficiency in a population of medical students of both gender from the university of las palmas de gran canaria. methods: 103 medical stud ...201121555257
non-human viruses developed as therapeutic agent for use in humans.viruses usually infect a restricted set of host species, and only in rare cases does productive infection occur outside the natural host range. infection of a new host species can manifest as a distinct disease. in this respect, the use of non-human viruses in clinical therapy may be a cause for concern. it could provide the opportunity for the viruses to adapt to the new host and be transferred to the recipient's relatives or medical caretakers, or even to the normal host species. such environm ...201121560181
animal sentinels for environmental and public health.studies of the effects of environmental exposures on domestic and wild animals can corroborate or inform epidemiologic studies in humans. animals may be sensitive indicators of environmental hazards and provide an early warning system for public health intervention, as exemplified by the iconic canary in the coal mine. this article illustrates the application of animal sentinel research to elucidate the effects of exposure to traditional and emerging contaminants on human health. focusing on env ...201121563712
ancient dna of the extinct lava shearwater (puffinus olsoni) from the canary islands reveals incipient differentiation within the p. puffinus complex.the loss of species during the holocene was, dramatically more important on islands than on continents. seabirds from islands are very vulnerable to human-induced alterations such as habitat destruction, hunting and exotic predators. for example, in the genus puffinus (family procellariidae) the extinction of at least five species has been recorded during the holocene, two of them coming from the canary islands.201021209838
paleoparasitologic, paleogenetic and paleobotanic analysis of xviii century coprolites from the church la concepción in santa cruz de tenerife, canary islands, spain.we present the results of a paleoparasitologic, paleogenetic and paleobotanic analysis of coprolites recovered during the excavation of the church la concepción in santa cruz de tenerife. coprolites (n = 4) were rehydrated and a multidisciplinary analysis was conducted. the paleobotanic analysis showed numerous silicates, seeds and fruits of the family moraceae. in the paleoparasitologic study, ascaris sp. eggs (n = 344) were identified. the paleogenetic results confirmed the ascaris sp. infecti ...201021225205
healthy mind and body in a healthy work environment.to assess the relationship between psychological distress and physical somatic symptoms as well as work environment conditions in the diverse population of dentists based in the canary islands (spain).201021302737
[social perception of the spanish law for young offenders].the implementation of the law 5/2000 for the regulation of criminal responsibility for minors has led to a change in interventions in cases of juvenile offenders. this law promotes the educational and rehabilitative aims of the measures imposed. however, the focus of the media on the most serious cases has generated considerable alarm in society in general. the aim of this study is to determine the social perception of law 5/2000. for this purpose, a sample of 936 people from the autonomous regi ...201021044525
response to intervention (rti) model: a promising alternative for identifying students with learning disabilities?until recently, in the united states, the traditional way to identify students with specific learning disabilities (sld) was through the discrepancy model where student iqs were compared to their level of achievement. however, educators and researchers alike have questioned this model as a means to define and identify students with sld. the 2004 reauthorization of the individuals with disabilities education improvement act (ideia) includes the use of response to intervention (rti) as possible al ...201021044534
implementation of response to intervention (rti) model in spain: an example of a collaboration between canarian universities and the department of education of the canary islands.the purpose of this study was to examine the effectiveness of second tier intervention at-risk readers within the context of a response to intervention approach. the study was conducted in the canary islands (spain), directed by research team ¨dificultades de aprendizaje, psicolingüística y nuevas tecnologías¨ (dea&nt) from university of la laguna, and supported by the government of the canary islands. a sample of 1.123 spanish children from fourteen schools districts were given the spanish adap ...201021044535
closed-loop bird-computer interactions: a new method to study the role of bird calls.in the field of songbird research, many studies have shown the role of male songs in territorial defense and courtship. calling, another important acoustic communication signal, has received much less attention, however, because calls are assumed to contain less information about the emitter than songs do. birdcall repertoire is diverse, and the role of calls has been found to be significant in the area of social interaction, for example, in pair, family, and group cohesion. however, standard me ...201021052754
health related quality of life of canary island citizens.the aim of the study was to describe the health-related quality of life of canarian population using information from the canary island health survey and three observational studies developed in the canary islands.201021054832
divergence times and colonization of the canary islands by gallotia lizards.the canary islands have become a model region for evolutionary studies. we obtained 1.8 kbp of mtdna sequence from all known island forms of the endemic lizard genus gallotia and from its sister taxon psammodromus in order to reanalyze phylogenetic relationships within the archipelago, estimate lineage divergence times, and reconstruct the colonization history of this group. well-supported phylogenies were obtained using maximum parsimony and bayesian inference. previous studies have been unable ...201020307675
population expansion in the north african late pleistocene signalled by mitochondrial dna haplogroup u6.the archaeology of north africa remains enigmatic, with questions of population continuity versus discontinuity taking centre-stage. debates have focused on population transitions between the bearers of the middle palaeolithic aterian industry and the later upper palaeolithic populations of the maghreb, as well as between the late pleistocene and holocene.201021176127
trypanosoma evansi: recent outbreaks in europe.here, two recent outbreaks of trypanosoma evansi infection in mainland france and spain associated with the importation of dromedary camels from the canary islands, are reported. the disease is well-known on the archipelago since 1997 and many efforts have been made towards control and eventual eradication, but some areas still remain affected. both mainland outbreaks were controlled by means of massive treatments and monthly serological, parasitological and molecular (pcr) evaluations carried o ...201020851526
opposite poles: a comparison between two spanish regions in health-related quality of life, with implications for health policy.although health is one of the main determinants of the welfare of societies, few studies have evaluated health related quality of life in representative samples of the population of a region or a country. our aim is to describe the health-related quality of life of the inhabitants of two quite different spanish regions (canary islands and catalonia) and to compare the prevalence of health problems between age-sex groups.201020868523
healthy and unhealthy migrant effect on the mortality of immigrants from wealthy countries residing in spain.this study attempts to identify the possible existence of a healthy migrant effect and an unhealthy migrant effect on the mortality of immigrants from wealthy countries who move to spain. immigrants aged 35-64 years from france, germany, great britain and 16 other wealthy oecd countries who resided in spain were compared with respect to: (1) mortality from cancer, cardiovascular disease, and all other diseases and (2) employment status, duration of residence, and educational level, in two geogra ...201020878542
genetic differentiation of the house mouse around the mediterranean basin: matrilineal footprints of early and late colonization.the molecular signatures of the recent expansion of the western house mouse, mus musculus domesticus, around the mediterranean basin are investigated through the study of mitochondrial d-loop polymorphism on a 1313 individual dataset. when reducing the complexity of the matrilineal network to a series of haplogroups (hgs), our main results indicate that: (i) several hgs are recognized which seem to have almost simultaneously diverged from each other, confirming a recent expansion for the whole s ...201020880891
disentangling ancient interactions: a new extinct passerine provides insights on character displacement among extinct and extant island finches.evolutionary studies of insular biotas are based mainly on extant taxa, although such biotas represent artificial subsets of original faunas because of human-caused extinctions of indigenous species augmented by introduced exotic taxa. this makes it difficult to obtain a full understanding of the history of ecological interactions between extant sympatric species. morphological bill variation of fringilla coelebs and f. teydea (common and blue chaffinches) has been previously studied in the nort ...201020886036
the role of wild rodents in the transmission of trypanosoma evansi infection in an endemic area of the canary islands (spain).trypanosoma evansi was diagnosed for the first time in camels in the canary islands in 1997. several sanitary measures including treatment of infected animals were taken; however, nowadays a little area is still infected. in order to determine possible reservoirs 138 wild rodents were trapped, 64 of them in the infected farms and the remaining 74 in other areas. the captured species were rattus rattus (24), rattus norvegicus (69) and mus musculus domesticus (45). serological (catt/t. evansi), pa ...201020888126
the canary in the coalmine: the sensitivity of mesolimbic dopamine to environmental adversity during development.the hypothalamic-pituitary-adrenal axis has been the focus of extensive research with regard to the phenotypic plasticity this system shows in response to environmental influences on mammalian development. this review proposes that the mesolimbic dopamine system is similarly reactive to indicators of environmental adversity during development. physical, physiological, and toxicological stressors encountered during perinatal development have been routinely demonstrated to affect dopamine neurophy ...201020888857
mitochondrial dna introgression in the european abalone haliotis tuberculata tuberculata: evidence for experimental mtdna paternal inheritance and a natural hybrid sequence.two subspecies of the european abalone have been morphologically recognized: haliotis tuberculata tuberculata, present in the north atlantic, and haliotis tuberculata coccinea, present in the canary islands. among the different nuclear markers used to differentiate these two subspecies, the sperm lysin gene was the most reliable, leading to a 2.2% divergence. concerning the subunit i of the mitochondrial cytochrome oxydase gene (coi), we observed a difference of 3.3% between the two subspecies. ...201020938796
effect of forest clear-cutting on subtropical bryophyte communities in waterfalls, on dripping walls, and along streams.forested freshwater ecosystems worldwide are threatened by a number of anthropogenic disturbances, such as water pollution and canalization. transient or permanent deforestation can also be a serious threat to organisms in forested watersheds, but its effects on different types of freshwater systems has been little studied. we investigated lotic bryophyte communities on rock and soil in subtropical cloud laurel forests on la gomera island in the canary islands, spain, and asked whether the respo ...201020945765
favorable fragmentation: river reservoirs can impede downstream expansion of riparian weeds.river valleys represent biologically rich corridors characterized by natural disturbances that create moist and barren sites suitable for colonization by native riparian plants, and also by weeds. dams and reservoirs interrupt the longitudinal corridors and we hypothesized that this could restrict downstream weed expansion. to consider this "reservoir impediment" hypothesis we assessed the occurrences and abundances of weeds along a 315-km river valley corridor that commenced with an unimpounded ...201020945766
applicability of microwave-assisted extraction combined with lc-ms/ms in the evaluation of booster biocide levels in harbour sediments.a new sample treatment method for the determination of four common booster biocides (diuron, tcmtb, irgarol 1051 and dichlofluanid) in harbour sediment samples has been developed that uses liquid chromatography-tandem mass spectrometry (lc-ms/ms) after microwave-assisted extraction, followed by clean-up and a solid phase extraction preconcentration step (mae-spe). the effects of different variables on mae-spe were studied. the recoveries obtained were greater than 75%, and the relative standard ...201020947123
prevalence of neutralizing antibodies to west nile virus in eleonora's falcons in the canary islands.birds are the major amplifying host for west nile virus (wnv), a flavivirus that may affect humans and transmitted by bloodsucking vectors. eleonora's falcons (falco eleonorae) migrate to the canary islands annually from wnv-endemic regions. to investigate the possible role of eleonora's falcons in the circulation of wnv, we measured wnv-specific antibodies in 81 falcons captured in 2006. none of the nestlings but 14.8% of the adults had wnv-neutralizing antibodies. rt-pcr did not detect flavivi ...201020966288
[a decade of reflection on health plans in spain. sespas report 2010].this article reports the experience of the working group of the sespas-scsp (spanish society of public health and healthcare administration-canary islands society of public health) in health policy and planning during the first decade of the 21st century and its possible impact on the design of health planning. we review the conclusions reached from 2000 to 2008 in the first five biannual planning and health policy meetings that took place during that period. the workshops were designed with two ...201021074905
[prevalence of obesity in pregnant women of canary islands, spain.]background and objective: different epidemiological studies have shown that maternal excess of weight during pregnancy is associated with adverse outcomes of pregnancy, childbirth and morbidity of the neonate. prevalence of obesity in a pregnant population of canary islands is reported here. subjects and methods: the group studied was an integrated cohort of all the pregnant women being followed-up at the materno-infant university hospital of the canarias [hospital universitario materno-infantil ...201021087776
representation of the bird's own song in the canary hvc: contribution of broadly tuned neurons.in songbirds, neurons in the song nucleus hvc exhibit a striking example of selective auditory response, firing more to playback of the bird's own song (bos) than to conspecific songs. this song selectivity has been found in various songbird species, both those that sing a single individual-specific song as well as those, such as the canary, in which both song structure and individual-identity encoding in song is more complex. in the present study, we investigated how the bos is represented in t ...201021093548
background levels of polychlorinated biphenyls in the population of the canary islands (spain).polychlorinated biphenyls (pcbs) are persistent and toxic compounds that have been detected in human serum or tissues worldwide. the objective of our study was to determine serum pcb levels in a representative sample of the general population of the spanish archipelago of the canary islands (607 serum samples from subjects aged between 6 and 75 years) in order to establish the main causes of this contamination and to evaluate the potential risks posed by these chemicals on the population through ...201021106193
diet of the extinct lava mouse malpaisomys insularis from the canary islands: insights from dental microwear.malpaisomys insularis is a mouse-like rodent endemic to the eastern canary islands. it became extinct during the fourteenth century. it was a remarkable species living under hyperarid conditions. a dental microwear analysis was performed in order to determine its former diet. the elevated number of fine scratches found in malpaisomys molars suggests that it consumed a significant part of poaceae, grass consumption leaving the most distinctive features on dental wear facets. a graminivorous diet ...201021107517
molecular structural studies of lichen substances with antimicrobial, antiproliferative, and cytotoxic effects from parmelia subrudecta.lecanoric acid (1), orsellinic acid methyl ester (2), orcinol (3), and usnic acid (4) were isolated from the lichen parmelia subrudecta, collected on palma of the canary islands, spain. compounds 1, 2, 3, and 4 were purified by solvent extraction, silica gel column chromatography, and preparative high-performance liquid chromatography (hplc) consecutively. the structures of the four compounds were elucidated by one- and two-dimensional nuclear magnetic resonance (nmr) experiments and mass spectr ...201021108141
two trebouxia algae with different physiological performances are ever-present in lichen thalli of ramalina farinacea. coexistence versus competition?ramalina farinacea is an epiphytic fruticose lichen that is relatively abundant in areas with mediterranean, subtropical or temperate climates. little is known about photobiont diversity in different lichen populations. the present study examines the phycobiont composition of several geographically distant populations of r. farinacea from the iberian peninsula, canary islands and california as well as the physiological performance of isolated phycobionts. based on anatomical observations and mol ...201021134099
measurement of body temperature in adult patients: comparative study of accuracy, reliability and validity of different devices.background and aims: we compared a range of alternative devices with core body temperature measured at the pulmonary artery to identify the most valid and reliable instrument for measuring temperature in routine conditions in health services. methods: 201 patients from the intensive care unit of the candelaria university hospital, canary islands, admitted to hospital between april 2006 and july 2007. all patients (or their families) gave informed consent. readings from gallium-in-glass, reactive ...201021145551
pregnane steroidal glycosides and their cytostatic activities.four new steroidal glycosides such as 3-o-6-deoxy-3-o-methyl-β-d-allopyranosyl-(1 → 4)-β-d-oleandropyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-cymaropyranoside-12-β-tigloyl-14-β-hydroxy-17-β-pregnane (1), 3-o-6-deoxy-3-o-methyl-β-d-allopyranosyl-(1 → 4)-β-d-oleandropyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4)-β-d-cymaropyranoside-12-β-(2'-amino)-benzoyl-14-β-hydroxy-17-β-pregnane (2), 3-o-6-deoxy-3-o-methyl-β-d-allopyranosyl-(1 → 4)-β-d-oleandropyranosyl-(1 → 4)-β-d-cymaropyranosyl-(1 → 4 ...201021147757
the canary seems fine: the effects of the economy on job-seeking experiences of recent dermatology training program graduates. 201020576320
common variants of the neuropeptide expressing tachykinin genes and susceptibility to asthma: a case-control study.since tachykinins appear to be involved in the pathogenesis of allergic asthma, we investigated a possible association between 28 single nucleotide polymorphisms of the tachykinin genes tac1, tac3 and tac4, and asthma susceptibility. a case-control study was conducted on 102 patients and 100 healthy subjects from the canary islands (spain). a significant association with asthma was observed for two snps: rs2291855 in the tac3 gene conferring asthma protection (odds ratio [or]: 0.46; 95% confiden ...201020580442
whole-genome characterization of a novel polyomavirus detected in fatally diseased canary birds.polyomaviruses of birds are aetiological agents of acute inflammatory diseases in non-immunocompromised hosts, which is in contrast to mammalian polyomaviruses. vp4, an additional structural protein encoded by the viral genomes of the known avian polyomaviruses, has been suggested to contribute to pathogenicity through loss of cells following induction of apoptosis. four distinct bird polyomaviruses have been identified so far, which infect crows, finches, geese and parrots. using broad-spectrum ...201020797969
evolutionary diversification of the genus theba (gastropoda: helicidae) in space and time: a land snail conquering islands and continents.among oceanic islands, the canary islands offer exceptional opportunities for studying speciation processes due to their habitat diversity and well documented geological history. based on a combined coi+its1 data set for more than 140 specimens, we studied the diversification of the land snail genus theba on the canary islands and adjacent african and european continental areas. phylogenetic analyses resulted in the recognition of 18 genetically distinct clades including at least three new speci ...201020800098
dietary intake of aluminum in a spanish population (canary islands).the aim of this study was to analyze the aluminum content in foods and beverages most commonly consumed by the canary island population to determine the dietary intake of this metal throughout the canary islands as a whole and in each of the seven islands (gran canaria, lanzarote, fuerteventura, tenerife, la palma, la gomera, and el hierro). four hundred and forty samples were analyzed by icp-oes. estimated total intake of aluminum for the canary population was 10.171 mg/day, slightly higher tha ...201020809646
hormonal acceleration of song development illuminates motor control mechanism in canaries.in songbirds, the ontogeny of singing behavior shows strong parallels with human speech learning. as in humans, development of learned vocal behavior requires exposure to an acoustic model of species-typical vocalizations, and, subsequently, a sensorimotor practice period after which the vocalization is produced in a stereotyped manner. this requires mastering motor instructions driving the vocal organ and the respiratory system. recently, it was shown that, in the case of canaries (serinus cana ...201020812319
genetics of flavonoid, carotenoid, and chlorophyll pigments in melon fruit rinds.external color has profound effects on acceptability of agricultural products by consumers. carotenoids and chlorophylls are known to be the major pigments of melon (cucumis melo l.) rinds. flavonoids (especially chalcones and anthocyanins) are also prominent in other fruits but have not been reported to occur in melons fruit. we analyzed the pigments accumulating in rinds of different melon genotypes during fruit development. we found that melon rind color is based on different combinations of ...201020815398
influence of the cultivar on the organic acid and sugar composition of potatoes.citric, malic, tartaric, oxalic, ascorbic, aconitic and fumaric acids, and sucrose, fructose and glucose, were determined in ten potato cultivars (azucena negra, bonita, bonita negra, borralla, colorada de baga, mora, negra, palmera lagarteada, peluca blanca and terrenta) from the canary islands in order to differentiate them. the influence of the production zone was also considered.201020718025
coxiella burnetii infections in domestic ruminants in canary islands (spain). 201020723162
ability of various plant species to prevent leakage of n, p, and metals from sewage sludge.the preventive effect of vegetation on nutrient and metal leakage from sewage sludge (ss) used in treatment of mine waste was investigated. in a 10-week greenhouse study, the release of ammonium, nitrate, phosphate, cd, cu, and zn from ss was analyzed in the absence (control) and presence of basket willow, fireweed, reed canary grass (rcg), and scots pine. plants significantly decreased the leakage by reducing the amount of leachate, and lowered the concentrations of phosphate (to 0.1 mg l(-1)), ...201020734629
temporal and territorial analysis of multiple deliveries in spain (1900-2006).temporal variations in the frequency of multiple maternities in many western european countries have been described. however, within a single country, regional differences are observed. urban industrialized regions and rural agricultural areas have experienced in recent decades a distinct decline in multiple deliveries, which in cases have been related to maternal age and parity changes. research on multiple deliveries in spain is scarce and none of the studies go back to the beginning of the 20 ...201020397751
distribution of size fractionated dissolved iron in the canary basin.the distribution of size fractionated dissolved iron (dfe, <0.2 mum) species was determined in the upper water column (0-150 m) of the canary basin (25-32 degrees n and 18-24 degrees w) on a research cruise in october 2002. a dfe concentration gradient resulting from a decrease in both soluble iron (sfe, <0.02 microm) and colloidal iron (cfe, 0.02-0.2 microm) was shown to extend from the coast of north west africa into the oligotrophic gyre (varying from approximately 1 nm in the shelf region to ...201020399495
association between glycemic index, glycemic load, and fructose with insulin resistance: the cdc of the canary islands study.the involvement of carbohydrates in triggering insulin resistance (ir) remains a source of controversy.201020419457
epidemiological survey of canine heartworm disease on the island of gran canaria (canary islands - spain) between 2000 and 2008.canine cardiopulmonary dirofilariosis caused by dirofilaria immitis is endemic on the island of gran canaria. epidemiological surveys have shown differences in the prevalence of heartworm disease in the canine population of the island between 1989 and 1998. the aim of the present study was to follow-up the prevalence of d. immitis in both the canine population as a whole and the canarian warren hound population on gran canaria between 2000 and 2008. prevalences observed were always significantly ...201020605072
a new application of streptavidin immunocap for measuring igg antibodies against non-available commercial antigens.enzyme immunoassay has been successfully used for the diagnosis of hypersensitivity pneumonitis (hp), but there are difficulties in standardising this method because of the difficulty in obtaining stable solid phases from a huge variety of heterogeneous antigenic sources. with this in mind, the aim of this work was to demonstrate the usefulness of the standard available fluoro-enzyme-immuno-assay (feia) to measure specific igg to uncommon, commercially unavailable hp-causing antigens.201020619254
an evaluation of a macroalgal bioassay tool for assessing the spatial extent of nutrient release from offshore fish farms.in this study we develop and evaluate a macroalgal bioassay tool for monitoring the spatial extent of dissolved wastes loaded from offshore fish farms into the marine coastal ecosystem. this tool is based on the analysis of the nitrogen stable isotope ratio (delta(15)n) in tissues of several benthic primary producers (macroalgae and posidonia oceanica epiphytes) incubated, by means of incubation devices, in the water column at increasing distances (from 0 m to 1000 m) from the fish cages. the bi ...201020621769
update on methodologies available for ciguatoxin determination: perspectives to confront the onset of ciguatera fish poisoning in europe.ciguatera fish poisoning (cfp) occurs mainly when humans ingest finfish contaminated with ciguatoxins (ctxs). the complexity and variability of such toxins have made it difficult to develop reliable methods to routinely monitor cfp with specificity and sensitivity. this review aims to describe the methodologies available for ctx detection, including those based on the toxicological, biochemical, chemical, and pharmaceutical properties of ctxs. selecting any of these methodological approaches for ...201020631873
electrophysiological and morphological development of the inner ear in belgian waterslager canaries.belgian waterslager (bw) canaries have an inherited hearing loss due to missing and abnormal hair cells, but it is unclear whether the loss is congenital or developmental. we used auditory brainstem responses and scanning electron microscopy to describe the development of auditory sensitivity and hair cell abnormalities in bw and non-bw canaries. in both strains, adult abr thresholds were higher than behavioral thresholds, but bw canaries exhibited higher thresholds than non-bw canaries across a ...201020638464
early warning: an ailing canary in the mine. 201020644096
[terminal kidney disease associated with diabetes in the canary islands: a public heath problem with high economic cost and human suffering]. 201020651878
[economic evaluation of haemodialysis. analysis of cost components based on patient-specific data].hemodialysis (hd) cost analysis provides information about the economic impact of the disease on the community. its knowledge is crucial to adequate and optimize health resources. our aim was to study sanitary and non-sanitary direct costs of hd, based on patients individual data. furthermore, the effect of sociocultural factors and comorbidity on costs was evaluated.201020651881
comparison of planted soil infiltration systems for treatment of log yard runoff.treatment of log yard runoff is required to avoid contamination of receiving watercourses. the research aim was to assess if infiltration of log yard runoff through planted soil systems is successful and if different plant species affect the treatment performance at a field-scale experimental site in sweden (2005 to 2007). contaminated runoff from the log yard of a sawmill was infiltrated through soil planted with alnus glutinosa (l.) gärtner (common alder), salix schwerinii x viminalis (willow ...201020669729
canine dirofilariosis caused by dirofilaria immitis is a risk factor for the human population on the island of gran canaria, canary islands, spain.the aim of the present study was compare the prevalence of d. immitis in dogs and seroprevalence in humans of gran canaria (canary islands, spain) taking into consideration the four isoclimatic areas of the island. a close relationship between the prevalence of dirofilaria immitis in dogs and the seroprevalence in humans, in each isoclimatic area, was observed. the highest seroprevalence of infection in both canine and human hosts were found in a strip of mid-range altitude with 25.47% and 30.4% ...201020676685
canary in a coal mine: does the plastic surgery market predict the american economy?economic tools have been used in the past to predict the trends in plastic surgery procedures. since 1992, u.s. cosmetic surgery volumes have increased overall, but the exact relationship between economic downturns and procedural volumes remains elusive. if an economic predicting role can be established from plastic surgery indicators, this could prove to be a very powerful tool.201020679849
identification and characterization of uncoupling protein in heart and muscle mitochondria of canary birds.an uncoupling protein (cucp) was identified in heart and skeletal muscle mitochondria of canary birds. cucp was immunodetected using polyclonal antibodies raised against murine ucp2. its molecular mass was similar to those of mammalian ucps (32 kda). the activity of cucp was stimulated by palmitic acid (pa) and inhibited by gtp mainly in state 3 respiration. additions of pa augmented state 4 respiration and lowered the adp/o ratio. thus, the activity of cucp diverted energy from oxidative phosph ...201020686918
ciguatera fish poisoning on the west africa coast: an emerging risk in the canary islands (spain).ciguatera fish poisoning (cfp) is endemic in certain tropical and subtropical regions of the world. cfp had not been described on the west africa coast until a 2004 outbreak in the canary islands. in 2008-2009, two additional outbreaks of ciguatera occurred. individuals afflicted had consumed lesser amberjack (seriola rivoliana) captured from nearby waters. caribbean ciguatoxin-1 (c-ctx-1) was confirmed in fish samples by lc-ms/ms. ciguatoxic fish in this region may pose a new health risk for th ...201020692274
lotus endemic to the canary islands are nodulated by diverse and novel rhizobial species and symbiotypes.genetic and symbiotic characterization of 34 isolates from several lotus species endemic to the canary islands showed extraordinary diversity, with bacteria belonging to different species of the genera mesorhizobium (17 isolates), sinorhizobium (12 isolates) and rhizobium/agrobacterium (5 isolates). in a previous report, we showed that the sinorhizobium isolates mostly belonged to s. meliloti. here, we focused on the remaining isolates. the lotus mesorhizobial strains were distributed in the rrs ...201020447791
[nursing in the canary islands and the academic and professional changes].to find out the wishes of nurses in the canary islands in light of the new academic and professional changes, and to identify whether the sociodemographic variables can influence their decisions.201020452797
fractionation of hairless canary seed (phalaris canariensis) into starch, protein, and oil.canary seed is an important specialty crop in canada. the current market for this true cereal (i.e., belonging to the family poaceae as wheat) is limited to feed for caged birds. however, canary seed holds a promise for many food and industrial applications based on its composition. three wet milling procedures based on ethanol (e), water (w), and alkaline (a) extractions used in different order were investigated to determine extraction efficiency and purity of starch, protein, oil, and fiber se ...201020465306
molecular evolution of trichuris muris isolated from different muridae hosts in europe.a phylogeographic study was carried out of trichuris muris, nematode parasitizing murinae rodents from the muridae family, isolated from four different hosts and from different geographical regions of europe by amplification and sequencing of the its1-5.8s-its2 fragment of the ribosomal dna. t. muris was found in the apodemus sylvaticus, apodemus flavicollis, mus domesticus, and rattus rattus rodents. the molecular results confirm the presence of dna polymorphisms among t. muris isolates from eu ...201020473527
herpesvirus infection with severe lymphoid necrosis affecting a beaked whale stranded in the canary islands.this report describes the pathologic findings in a single, adult female cuvier's beaked whale ziphius cavirostris stranded in the canary islands. the study indicated that this whale died with a severe, systemic, herpesviral infection and clearly exhibited lesions different from those of the fat and gas embolic syndrome described in beaked whale mass strandings associated with sonar exposure. this is the first report of a cetacean alphaherpesvirus infection of the lymphoid system in a beaked whal ...201020481092
[prevalence of processes and pathologies dealt with by the pre-hospital emergency medical services in spain].this study was carried out by contacting 26 medical emergency services (mes), through survey, with final data obtained from 22. population covered: 42,538,730. total number of calls: 7,656,768, with 711,228 interventions. number of operational forces: intensive care units (mobile-icus): 329, rapid intervention vehicles (riv) 20, health ambulances 39 and medical helicopters 39 (4 of them 24 hour: canary islands and castile-la mancha) and 3 airplanes. interventions: mobile-icus: 94.3%, medical hel ...201020508676
taqman real-time pcr detects avipoxvirus dna in blood of hawai'i 'amakihi (hemignathus virens).avipoxvirus sp. is a significant threat to endemic bird populations on several groups of islands worldwide, including hawai'i, the galapagos islands, and the canary islands. accurate identification and genotyping of avipoxvirus is critical to the study of this disease and how it interacts with other pathogens, but currently available methods rely on invasive sampling of pox-like lesions and may be especially harmful in smaller birds.201020523726
suitability of electronic mini-boluses for the early identification of goat kids and effects on growth performance and development of the reticulorumen.a total of 60 twin-goat kids (30 male and 30 female) of the canary island majorera dairy breed were used in 2 experiments to evaluate 2 types of electronic identification mini-boluses and their effects on rearing performances and reticulorumen development. electronic identification mini-boluses were cylindrical and made of ceramic materials (b1, 9.0 g and 38.5 × 9.5 mm; b2, 16.3 g and 42.2 × 12.2 mm), contained a 32-mm half-duplex passive transponder, and were administered to kids at different b ...201020525934
contrasting patterns of morphological and physiological differentiation across insular environments: phenotypic variation and heritability of light-related traits in olea europaea.phenotypic variation of traits can reflect the ability of plants to adjust to particular environments, but how much of this variation is heritable is not frequently analyzed in natural populations. in the present paper, we investigated the patterns of phenotypic expression in light-related leaf traits of olea europaea subsp. guanchica, a woody sclerophyllous species endemic to the canary islands. we explored phenotypic differentiation and heritable variation across several island populations dif ...201020532918
seroprevalence of coxiella burnetii in domestic ruminants in gran canaria island, spain.coxiella burnetii is the causative agent of q fever, a zoonosis with worldwide occurrence. in the canary islands, the overall seroprevalence in humans has been estimated to be 21.5%. gran canaria island concentrates the highest ruminant population in the archipelago and the prevalence of the human infection is 23.5%. to evaluate the seroprevalence in livestock and the affected areas in gran canaria island, a total of 1249 ruminants were randomly selected for this study (733 goats, 369 sheep and ...201020537108
a 75% reduction in herbicide use through integration with sorghum + sunflower extracts for weed management in wheat.to reduce herbicide use by 75%, integrated use of sorghum and sunflower extracts each at 18 l ha(-1) combined with 1/4(th) (75% less) of label rates of four herbicides (mesosulfuron + idosulfuron, metribuzin, phenoxaprop-p-ethyl and isoproturon) were investigated for the management of wild oat and canary grass, the two pernicious weeds in wheat fields worldwide.201020549775
effect of repeated exposure to plasmodium relictum (lineage sgs1) on infection dynamics in domestic canaries.parasites are known to exert strong selection pressures on their hosts and, as such, favour the evolution of defence mechanisms. the negative impact of parasites on their host can have substantial consequences in terms of population persistence and the epidemiology of the infection. in natural populations, however, it is difficult to assess the cost of infection while controlling for other potentially confounding factors. for instance, individuals are repeatedly exposed to a variety of parasite ...201020570591
spore film dosimeters are feasible for uv dose monitoring during heliotherapy.the objective of the study was to compare bacillus subtilis spore film dosimeters with a robertson berger uv meter (rb meter) and diary records for assessing personal uv-b doses during a 13-day heliotherapy (ht) for atopic dermatitis (ad). in addition, the relationship between the personal uv-b dose and change in serum 25-hydroxyvitamin d (25(oh)d) was studied. altogether 21 adult patients with ad completed the study arranged in the canary islands, either in january or march 2005. the spore film ...201020573044
diversity of vibrios in the haemolymph of the spider crab maja brachydactyla.the aim of this study was to characterise and identify vibrios isolated from the haemolymph of apparently healthy adult spider crabs (maja brachydactyla) wild-caught in the spanish localities of galician coast and in the canary islands and also from captive animals held at irta's facilities in the ebro delta of catalonia, north-west spanish mediterranean coast.201020374412
[mental disease, existence of diagnostic, use of psychotropic medication: differences by autonomous communities under the national health survey 2006].most of the studies on psychological distress in spain have been conducted in small geographical areas or specific population groups. however, there are no studies that provide representative data for each autonomous community (ac). the objectives of this paper are to determine, both in spain and in the ac, the prevalence of psychological distress, diagnosis, use of psychoactive medication, social support and self-perceived health, as well as to study the association between psychological distre ...201020376411
[study of the first outbreak of vana enterococcus faecium in the canary islands].in july, 2005 the first vancomycin-resistant enterococcus faecium (vref) with a genotype vana was isolated in hospital universitario de canarias (huc). from september to december 2005, vref vana was isolated from another 15 patients (3 nosocomial infections and 12 rectal carriers). all of them were kidney transplant patients hospitalized in the nephrology ward. this study describes the first vref vana outbreak in the huc and the epidemiological link of the first vref vana isolates found in anoth ...201020378209
[case report: sepsis and multi organ dysfunction syndrome in a patient returning from holiday on the canary islands: a difficult diagnosis].a forty-five year old male tourist suffers a febrile illness, delirium and severe abdominal pain on the fifth day of his holiday trip to the canary islands (spain). after hospitalization he presents a surgical abdomen which requires emergency laparotomy however without detectable pathology. progressing critical illness and septic shock leads to multiple organ failure, but focus identification is not possible. well after return to germany diagnostic uncertainty persists due to recurrent fever and ...201020387177
mesoscale eddies: hotspots of prokaryotic activity and differential community structure in the ocean.to investigate the effects of mesoscale eddies on prokaryotic assemblage structure and activity, we sampled two cyclonic eddies (ces) and two anticyclonic eddies (aes) in the permanent eddy-field downstream the canary islands. the eddy stations were compared with two far-field (ff) stations located also in the canary current, but outside the influence of the eddy field. the distribution of prokaryotic abundance (pa), bulk prokaryotic heterotrophic activity (pha), various indicators of single-cel ...201020357833
presence of c. albidus, c. laurentii and c. uniguttulatus in crop and droppings of pigeon lofts (columba livia).columba livia is an important reservoir and carrier of cryptococcus neoformans, cryptococcus uniguttulatus, cryptococcus laurentii and cryptococcus albidus. upper digestive tract of this species is also known as a habitat for cryptococcus neoformans. given the increasing clinical interest of this microorganism, 331 swabs from crop and 174 dropping samples from pigeon lofts in grand canary island have been studied. the obtained results show an extensive presence samples 81 positive (24.47%) of cr ...201020012367
outbreaks of keratoconjunctivitis in a camel herd caused by a specific biovar of moraxella canis.two tributyrin hydrolysis-negative moraxella isolates obtained in cases of keratoconjunctivitis in camelus dromedarius in the canary islands showed highest degrees of 16s rrna gene sequence similarity to moraxella canis. a level of dna relatedness to the m. canis type strain of 79% confirmed the identity of the isolates as a tributyrin hydrolysis-negative biovar of m. canis.201020032257
trypanosoma evansi infection in mainland spain.an outbreak of trypanosoma evansi infection that occurred in mainland spain is described. the outbreak occurred on an equine and camel farm to which dromedary camels from an infected area of the canary islands had recently been introduced. one of these camels developed clinical signs and t. evansi was discovered in a blood smear examination. the herd was evaluated in order to determine the extent of the disease. the results showed that 76% of the camels, 35% of the donkeys and 2% of the horses w ...201019864069
mitochondrial dna patterns in the macaronesia islands: variation within and among archipelagos.macaronesia covers four atlantic archipelagos: the azores, madeira, the canary islands, and the cape verde islands. when discovered by europeans in the 15th century, only the canaries were inhabited. historical reports highlight the impact of iberians on settlement in macaronesia. although important differences in their settlement are documented, its influence on their genetic structures and relationships has yet to be ascertained. in this study, the hypervariable region i (hvri) sequence and co ...201019927277
evidence for adaptive evolution of olfactory receptor genes in 9 bird species.it has been suggested that positive selection, in particular selection favoring a change in the protein sequence, plays a role in the evolution of olfactory receptor (or) gene repertoires in fish and mammals. ors are 7-transmembrane domain (tm) proteins, members of the g-protein-coupled receptor superfamily in vertebrate genomes, and responsible for odorant binding and discrimination. or gene repertoires in birds are surprisingly large and diverse, suggesting that birds have a keen olfactory sen ...201019965911
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