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a treatment plant receiving waste water from multiple bulk drug manufacturers is a reservoir for highly multi-drug resistant integron-bearing bacteria.the arenas and detailed mechanisms for transfer of antibiotic resistance genes between environmental bacteria and pathogens are largely unclear. selection pressures from antibiotics in situations where environmental bacteria and human pathogens meet are expected to increase the risks for such gene transfer events. we hypothesize that waste-water treatment plants (wwtps) serving antibiotic manufacturing industries may provide such spawning grounds, given the high bacterial densities present there ...201324204801
granulomatous pneumonia and hepatitis associated with providencia rettgeri infection in a crocodile monitor lizard (varanus salvadorii).the present report describes a case of granulomatous pneumonia and hepatitis in a male crocodile monitor lizard (varanus salvadorii). during the necropsy of the monitor lizard, multifocal to coalescing pale yellow lesions were observed in both lung lobes, as well as similar, though milder, changes in the liver, and an ulcerative lesion on the food pad of the right hindlimb. histopathologically, the presence of multiple necrotising, chronic granulomas containing bacterial clumps were observed in ...201323439291
effects of methanol extract of wedelia chinensis osbeck (asteraceae) leaves against pathogenic bacteria with emphasise on bacillus cereus.the antibacterial activity of the methanol extract of wedelia chinensis leave was studied and tested against three pathogenic gram positive bacteria (bacillus cereus, b. subtilis and stapylococcus aureus) and three pathogenic gram negative bacteria (escherichia coli, proteus rettgeri and pseudomonas aeruginosa) by the disk diffusion assay and broth dilution methods. the extract exhibited favourable antibacterial activity against the bacterial cells but was more potent against gram positive bacte ...201324403653
biosorption of aluminum, cobalt, and copper ions by providencia rettgeri isolated from wastewater.twenty-three bacterial isolates from polluted water and soil were screened for heavy metals resistance (i.e., al(3+), co(2+), and cu(2+)). the most potent isolate was identified by morphological characteristics, biochemical tests and confirmed by api20e kits as providencia rettgeri mam-4. removal of al(3+) from aqueous solution by p. rettgeri is more efficient (∼fourfold) than that by b. cereus atcc 11778 (a comparison strain) at concentration of 200 mg l(-1) al(3+). p. rettgeri was able to remo ...201322915136
yersinia enterocolitica in sheep--a high frequency of biotype 1a.pigs are regarded as the main reservoir for human pathogenic yersinia enterocolitica, which is dominated by bioserotype 4/o:3. other animals, including sheep, have occasionally been reported as carriers of pathogenic strains of y. enterocolitica. to our knowledge, this is the first study performed in the nordic countries in which the presence of y. enterocolitica in sheep is investigated.201222748116
spread of ctx-m-15 positive providencia spp. causing urinary tract infections at the university hospital split in croatia.during 2010-2011, six providencia spp. (five providencia stuartii and one providencia rettgeri) urine isolates with unusual resistance phenotype were collected from various hospital units at the university hospital split in croatia. the aim of the study was to analyze the mechanisms of resistance to expanded-spectrum cephalosporins.201222926370
prevalence of providencia strains among children with diarrhea in japan.in the present study, we examined the prevalence of providencia spp. strains among children with diarrhea in japan. we developed a providencia genus-specific polymerase chain reaction (pcr) method, and the specificity and sensitivity was evaluated to be 100% with various bacterial strains including 7 genera and 13 species. five of 345 samples (1.4%) were positive by pcr using a providencia genus-specific primer targeting the 16s rrna gene. the single species providencia rettgeri was isolated fro ...201223183210
synthesis and evaluation of antimicrobial activity of 4h-pyrimido[2,1-b]benzothiazole, pyrazole and benzylidene derivatives of curcumin.a novel, one-pot, simple, efficient procedure for 4h-pyrimido[2,1-b]benzothiazole (4a-h), pyrazole (6a-d) and benzylidene (7a-d) derivatives of curcumin under solvent and solvent free conditions in microwave with good yield is have been synthesized. the synthesized compounds were evaluated for their antibacterial activity against gram-positive and gram-negative bacteria viz. staphylococcus aureus, pseudomonas aeruginosa, salmonella typhi, escherichia coli, bacillus cereus and providencia rettger ...201222683240
no effect of wolbachia on resistance to intracellular infection by pathogenic bacteria in drosophila melanogaster.multiple studies have shown that infection with the endosymbiotic bacterium wolbachia pipientis confers drosophila melanogaster and other insects with resistance to infection by rna viruses. studies investigating whether wolbachia infection induces the immune system or confers protection against secondary bacterial infection have not shown any effect. these studies, however, have emphasized resistance against extracellular pathogens. since wolbachia lives inside the host cell, we hypothesized th ...201222808174
high load of multi-drug resistant nosocomial neonatal pathogens carried by cockroaches in a neonatal intensive care unit at tikur anbessa specialized hospital, addis ababa, ethiopia. 201222958880
[focal and diffuse nesidioblastosis and persistent neonatal hyperinsulinemic hypoglycemia. a morphologic analysis of 12 patients]. 20123534873
estrogen receptor: a valid test for selection of breast cancer patients for endocrine ablation. 20124142813
the influence of miotics on the visual field. 20123507913
[indications and prognosis of the iso titanium cone system]. 20123471501
anesthesia-related maternal mortality in michigan, 1972 to 1984.we reviewed maternal deaths in the state of michigan occurring from 1972 through 1984. there were 15 maternal deaths in which anesthesia was considered the primary cause and 4 deaths in which anesthesia was a contributory factor. complications of regional anesthesia were the main cause of death during the early part of the period, whereas the inability to accomplish endotracheal intubation emerged as the principal cause of death in recent years. eleven of the 15 patients had undergone cesarean s ...20123394738
chronic glomerulonephritis with massive iga deposits.a total of 234 patients with chronic glomerulonephritis, detected on the basis of clinical, immunological and pathomorphological criteria, have been examined. a group of 23 chronic glomerulonephritis patients with massive deposits of immunoglobulin a found by immunofluorescent examination, has been separated on the basis of immunohistochemical studies. in this group, occurrence of different morphological forms of glomerulonephritis has been observed: 30.4% mesangial-proliferative glomerulonephri ...20124086240
chronic glomerulonephritis with massive iga deposits.a total of 234 patients with chronic glomerulonephritis, detected on the basis of clinical, immunological and pathomorphological criteria, have been examined. a group of 23 chronic glomerulonephritis patients with massive deposits of immunoglobulin a found by immunofluorescent examination, has been separated on the basis of immunohistochemical studies. in this group, occurrence of different morphological forms of glomerulonephritis has been observed: 30.4% mesangial-proliferative glomerulonephri ...20124086240
diagnosis of right ventricular involvement in chronic inferior myocardial infarction by means of body surface qrs changes.st segment elevation in right precordial leads is thought to be good predictor of right ventricular involvement in patients with acute inferior myocardial infarction. this view, however, is rapidly disappearing. therefore, using qrs changes in body surface potential maps in the chronic phase, we have attempted to differentiate patients with or without right ventricular involvement. thirty patients with chronic inferior myocardial infarction (2 or more months after onset) were studied, in whom 87 ...20123370768
skull development during anuran metamorphosis: i. early development of the first three bones to form--the exoccipital, the parasphenoid, and the frontoparietal.in anuran amphibians, cranial bones typically first form at metamorphosis when they rapidly invest or replace the cartilaginous larval skull. we describe early development of the first three bones to form in the oriental fire-bellied toad, bombina orientalis--the parasphenoid, the frontoparietal, and the exoccipital--based on examination of serial sections. each of these bones is fully differentiated by gosner stage 31 (hindlimb in paddle stage) during premetamorphosis. this is at least six gosn ...20123379643
reconstitution of the w/wv stem cell differentiation defect by infection with rauscher leukemia virus.hematopoietic stem cells of w/wv mice failed to produce macroscopically visible hematopoietic spleen colonies in irradiated recipient mice. infection of w/wv mice of the spleen focus-forming virus-susceptible genotype fv-2ss (dba/2) or fv-2rs (bd2f1) with rauscher leukemia virus (rlv) restored the spleen colony-forming capacity of the stem cells. the resulting spleen colonies had normal size and cellularity; the frequency of and ratio between granulocyte-macrophage and erythroid progenitor cells ...20123894753
experimental evaluation of the mitroflow pericardial heart valve prosthesis. part i. in vivo hemodynamic evaluation.evaluation of possible enhanced durability of the mitroflow pericardial heart valve prosthesis was undertaken in an experimental animal model using the chacma baboon. for comparison purposes a small series of 4 ionescu-shiley pericardial valves were also implanted. the 33 mitroflow prostheses implanted were all manufacturer's size 21mm and belonged to 4 different groups according to the process used for the preparation of the pericardium (process i to iv). the ionescu-shiley prostheses were all ...20123421506
doctors using lasers risk problems without proper training, protection. 20123405576
arteriolar oxygen reactivity: where is the sensor?the hypothesis that arterioles are intrinsically sensitive to oxygen was tested by comparing arteriolar diameter responses with local and global po2 changes in superfused hamster cheek pouch preparations. local po2 changes were produced by microapplication of fluid onto the surface of occluded or unoccluded aparenchymal arterioles or by cannulation and perfusion of arterioles in situ. global changes refer to po2 changes in the superfusate flowing over the entire preparation. local, effective po2 ...20123318502
changes in caloric nystagmus induced by vasodilating drugs.systemic blood flow, blood flow to the peripheral skin, middle ear, and temporal bone, and that to the inner ear of normal volunteers was manipulated selectively through the use of vasodilator drugs. the effect of selective vasodilation was monitored via changes in the temporal course of the slow-phase velocity of nystagmus evoked by bithermal caloric irrigation. drug influenced eye velocities were compared with control values measured before drug administration. eye velocities measured after ni ...20123485753
[late results of organ-sparing surgical treatment of patients with balkan endemic nephropathy and tumors of the upper urinary tract]. 20123437707
allergy: a leading role in otitis media with effusion.we have studied 35 children with seasonal allergic rhinitis confirmed by positive skin tests and rast to grass pollen. intranasal antigen provocation was performed to evaluate the function of the eustachian tube (et) and middle ear pressure (mep). tympanometry was used to evaluate the changes in mep, while valsava and toynbee tympanometric tests were employed to study the et function, and the changes in nasal airway resistance were measured by anterior rhinomanometry. et dysfunction (etd) and a ...20123318349
[pneumaturia and emphysematous cystitis. contribution of a new case with echographic images]. 20123310528
[contact lenses for the correction of ametropia: indications, adaptation, complications of wearing lenses]. 20123475745
[iatrogenesis of amalgam]. 20123256040
[various problems of immunological prevention: changes in the schedule of preventive vaccination]. 20123432015
[indirect cervical trauma: long-term adverse prognostic factors]. 20123423548
electrophoretic mobility, concentration, and activity of alpha 1-antitrypsin in serum of patients undergoing bone-marrow transplantation.we have observed an electrophoretically abnormal, nonfunctional species of alpha 1-antitrypsin in serum from patients who were receiving bone-marrow transplants for treatment of leukemia or aplastic anemia. three of four patients in whose serum this protein appeared died soon after; the fourth recovered, and the disappearance of the abnormal alpha 1-antitrypsin paralleled his recovery. this suggests that the inability to maintain functional activity of alpha 1-antitrypsin predisposes patients to ...20123542290
abnormal monocyte function in patients with kaposi's sarcoma.monocyte-mediated functions were evaluated in the peripheral blood mononuclear cells (pbmc) of 11 previously untreated patients with kaposi's sarcoma in association with the acquired immune deficiency syndrome (ks/aids). all patients had lymphadenopathy, an abnormal okt.4/okt.8 ratio, and a good performance status; none had clinically apparent infections at the time of testing. monocyte functional assessments included immunoregulatory activity in phytohemagglutinin-stimulated (pha) lymphoblastog ...20123485009
insights on death & dying. depression: bottled-up emotions. 20123386914
[pit and fissure sealants. the effect of etching depends on the differences in tooth surface cleaning methods, and the method of cleaning pits and fissures]. 20123526496
an outbreak of cholera in a refugee camp in africa.a total of 541 cases of cholera were observed between may 7 and july 19, 1985 among the 9,929 displaced persons present in a refugee camp in africa. in spite of malnutrition and other diseases affecting this population, only 12 deaths occurred. antiepidemic measures consisted of preparation of isolation-wards, treatment of contaminated materials, training of refugees and patient care. mass prophylaxis, initially considered, was dropped before the end of the epidemic.20123402580
extensor tendon involvement in smith's and faleazzi's fractures. 20123351262
13c nmr studies of carboxylate inhibitor binding to cobalt(ii) carboxypeptidase a.both 13c nmr and electronic absorption spectral studies on cobalt(ii) carboxypeptidase a in the presence of acetate and phenylacetate provide evidence for two binding sites for each of these agents. the transverse relaxation rate t2-1 for the 13c-enriched carboxyl groups of the inhibitors is significantly increased when bound to the paramagnetic cobalt carboxypeptidase as compared to the diamagnetic zinc enzyme. the acetate concentration dependence of t2p-1 shows two inflections indicative of se ...20123346659
Description of a 2,683-Base-Pair Plasmid Containing qnrD in Two Providencia rettgeri Isolates.qnr genes are plasmid-mediated quinolone resistance genes mainly harbored on large conjugative multiresistant plasmids. The qnrD gene was recently observed in Salmonella enterica on a small nonconjugative plasmid (p2007057). We describe two strains of Providencia rettgeri harboring qnrD on nonconjugative plasmids. The plasmids were 99% identical, with 2,683 bp and four open reading frames, including qnrD, but exhibited only 53% identity with the plasmid found in S. enterica.201221986831
[the postcholecystectomy syndrome]. 20123454415
vim and imp metallo-β-lactamases and other extended-spectrum β-lactamases in escherichia coli and klebsiella pneumoniae from environmental samples in a tunisian hospital.an extremely drug-resistant enterobacteriaceae species emerged in kasserine hospital, tunisia between 2009 and 2010 causing a local outbreak. we aimed to characterize extended-spectrum β-lactamase (esbl) and metallo-β-lactamase (mbl)-producing enterobacteriaceae from the hospital environment. swabs were collected from ten different wards from kasserine hospital, tunisia. a total of 46 isolates were cultured onto macconkey agar supplemented with ceftazidime to select for esbl-producing enterobact ...201121917010
Effective cohorting and "superisolation" in a single intensive care unit in response to an outbreak of diverse multi-drug-resistant organisms.Cohorting patients in dedicated hospital wards or wings during infection outbreaks reduces transmission of organisms, yet frequently, this may not be feasible because of inadequate capacity, especially in the intensive care unit (ICU). We hypothesized that cohorting isolation patients in one geographic location in a single ICU and using enhanced isolation procedures ("superisolation") can prevent the further spread of highly multi-drug-resistant organisms (MDRO).201121936667
fluoroquinolone-resistant uncomplicated urinary tract infections, chinese herbal medicine may provide help.we assessed the effects of chinese herbs on the uncomplicated urinary tract infections (utis) in women caused by fluoroquinolone-resistant strains. a total of 56 pre-menopausal women with uncomplicated utis caused by fluoroquinolone-resistant strains were included. urine cultures were carried out. all organisms were proved to be fluoroquinolone-resistant at baseline. the patients were orally administrated chinese herbal concoction for ten days. chinese herbal concoction eradicated the primary pa ...201122754063
the 'bn2' gene, a regulator for the onset of chromosome condensation. 20113067728
cancer and malnutrition--a critical interaction: a review. 20113917603
cancer and malnutrition--a critical interaction: a review. 20113917603
deficiency of eosinophil peroxidase detected by automated cytochemistry. 20113122494
xanthogranulomatous pyelonephritis with nephrocutaneous fistula due to providencia rettgeri infection.we describe what is to our knowledge the first case of xanthogranulomatous pyelonephritis combined with nephrocutaneous fistula caused by providencia rettgeri. surgical extirpation including nephrectomy and fistulectomy was successfully performed. the strain was identified by 16s rrna gene sequencing in both renal tissue and pus culture from the fistula.201121459904
transient heart block associated with head trauma.atrioventricular nodal block is a rare consequence of head trauma. we report a case of a 63-year-old male with coronary artery disease who sustained a skull fracture. twelve hours later the cardiac monitor recorded an episode of high-grade atrioventricular block with a ventricular escape rhythm. subsequent electrophysiologic evaluation revealed no abnormality of atrioventricular nodal conduction nor of intraventricular conduction. atrioventricular block after head trauma may be caused by enhance ...20113346929
transient heart block associated with head trauma.atrioventricular nodal block is a rare consequence of head trauma. we report a case of a 63-year-old male with coronary artery disease who sustained a skull fracture. twelve hours later the cardiac monitor recorded an episode of high-grade atrioventricular block with a ventricular escape rhythm. subsequent electrophysiologic evaluation revealed no abnormality of atrioventricular nodal conduction nor of intraventricular conduction. atrioventricular block after head trauma may be caused by enhance ...20113346929
factors associated with blood pressure in females with heavy exposure to cadmium. 20114041650
serial myocardial lactate metabolic changes after intracoronary thrombolysis in evolving myocardial infarction.to investigate whether early reperfusion (less than or equal to 3 hours) preserves aerobic myocardial metabolism in acute myocardial infarction, we examined serial changes in trans-cardiac lactate extraction after thrombolysis in 43 patients with acute antero-septal myocardial infarction. in the chronic phase, we also determined abnormally contracting segments as an index of infarct size and regional ejection fraction as an index of chronic regional cardiac function. in the early reperfusion gro ...20113184437
assessing familial aggregation of congenital cardiovascular malformations in case-control studies.recent data indicate that the familial aggregation of congenital cardiovascular malformations (ccvm) varies with the type of defect in the index case. using a logistic regression model that allows for dependence among family members, we calculated the risk of any ccvm to case relatives compared with relatives of controls. data from 3,908 first-degree relatives of 570 matched cases and controls identified from 1981 through 1985 by the baltimore-washington infant study were used in the analyses. o ...20113215508
self-report vs. instrumental measure in the assessment of the subjective effects of d-amphetamine. 20113153509
the correlates of research success.a survey was carried out of the undergraduate backgrounds and research achievements of 885 (94.1%) of all 940 medically qualified professors and readers in medical faculties in the united kingdom. a total of 217 (24.5%) of the graduates in these senior academic positions had graduated from oxford or cambridge and 137 (15.5%) had an intercalated bsc. the corresponding figures for a control group matched for sex and date of graduation were 118 (13.3%) for oxford and cambridge (academic to control ...20113115391
accessory molecules in t lymphocyte activation.the currently accepted hypothesis used to explain the role of lyt-2 and l3t4 in t cell activation proposes how these molecules interact with class i and ii major histocompatibility complex molecules, respectively, on the antigen-presenting or target cell, to increase the avidity of binding of the antigen-specific t cell receptor. this has been tested using two antigen-specific, class ii-restricted t cell clones expressing both lyt- and l3t4. inhibition of function was observed only with monoclon ...20113106237
[the usefulness of projective methods in the diagnosis of schizophrenia]. 20113043507
promoter selectivity of prokaryotic rna polymerases. 20113076288
[ultrasonics and directional doppler. study of superficial phlebitis of the lower extremities].the objective of the study was to evaluate the usefulness of ultrasonic methods: ultrasonography and doppler c.w. in the diagnosis of superficial varicose phlebitis. especially, measurement of the venous pressure (v.p.) at the posterior tibial (p.t.) and the greater saphenous vein (g.s.v.) in clino and orthostatism, have proved to be useful. in ten cases, one patient with a varicose in the thigh, was also found to have a femoral vein thrombosis secondary to a deep thrombus entering the junction. ...20113043475
abdominal operations without nasogastric tube decompression of the gastrointestinal tract.the routine use of nasogastric (ng) drainage during and after abdominal surgery was examined. one hundred and fifty patients who underwent various abdominal operations with a levine tube served as a control group (retrospective group). the tubeless study group (prospective group) of 150 patients was randomly and blindly divided into three equal subgroups. subgroup a patients were operated on without any ng tube. the tube in subgroup b patients was inserted after induction of anesthesia and remov ...20113190004
prednisone-induced behavioral and biological changes in medically healthy volunteers. 20113153514
[a case of recurrent epipharyngeal cancer showing complete disappearance following suppository administration of tegafur (sunfural rectal capsules)].a 55-year-old woman was diagnosed as having epipharyngeal cancer, characterized by t2n1m0 and poorly differentiated squamous cell carcinoma. she was treated by radiotherapy (primary site: 65 gy, neck: 75 gy) and the tumor completely disappeared. however, 4 months later, the tumor recurred in the epipharynx. tegafur in the form of a suppository (sunfural rectal capsules, 750 mg) was given once a day. during the course of epipharyngoscopic follow-up the tumor almost totally disappeared at a dose o ...20113122667
effects of calcium-channel antagonists on tardive dyskinesia and psychosis. 20113153502
acute phase reaction following chemotherapy. 20113118119
ganglion cells in the turtle retina contain the neuropeptide lant-6.this study investigated the presence of the neurotensin-related hexapeptide, lant-6, in retinal ganglion cells and their central projections in the turtle pseudemys scripta elegans. immunocytochemical techniques demonstrated that many of the cells in the ganglion cell layer of the turtle retina could be labeled with an antiserum specific for lant-6. radioimmunoassay and chromatographic analysis confirmed the presence of lant-6-related peptides in retina, as well as brain. several molecular forms ...20113339403
relationships among duration of infusion, dose, dosing interval, and steady-state plasma concentrations during intermittent intravenous infusions: studies with metronidazole.relationships among duration of infusion (t), dose, dosing interval (tau), maximum and minimum plasma drug concentrations at steady state (cmax,ss and cmin,ss, respectively), and the duration of effective plasma concentrations (td) during multidose intermittent infusion regimens were studied by computer simulation using metronidazole as a model drug. pharmacokinetic parameter values for metronidazole were obtained from the literature and the minimum effective plasma concentration (mec) was taken ...20113746634
hazardous effects of disinfection and sterilization chemicals. 20113215342
[background factors relating to the delay in hospitalization analyzed among recently hospitalized patients of pulmonary tuberculosis (author's transl)]. 20114845630
cleavage lines of the oral mucosa in japanese cadavers.cleavage lines were experimentally reproduced in the oral mucosa of japanese cadavers. they were investigated macroscopically and histologically. the reproduced cleavage lines showed little directional variation by sex or age. from the histological findings, the mucosal cleavage lines were interpreted to represent cleavage split along the direction of connective tissue fibres in the lamina propria.20113165386
disease and pregnancy in adolescent girls.the frequency of visits to the outpatient clinic, chief complaints, and pregnancies of adolescent girls were analyzed. the age distribution of adolescent girls who visited the clinic showed that the higher the age, the higher the frequency of menstrual cycle abnormalities. recently, increased sexual activity has been seen in teenagers and has caused problems, especially the increase in teenage pregnancies, contributing to increases in induced abortion. to avoid unwanted pregnancy of unmarried te ...20113252729
[ethical aspects of therapeutic borderline situations in intensive care]. 20113147854
microprocessor-controlled mixing system for rebreathing equilibration.a simple, economic, and accurate microprocessor system for the determination of mixed venous pco2 has been described. through the automatic gas mixing system, it is possible to facilitate the use of the rebreathing equilibration technique for the purpose of cardiac output calculations. it was also possible to flush the rebreathing bag within a brief time, providing the investigator with an automatic three-way valve driven by a solenoid.20113131062
adenocarcinoma of the lung presenting as hematemesis secondary to jejunal metastasis: a case report and review of the literature. 20113126420
[use of photosensitizing preparations in the treatment of cancer of the orl organs]. 20113067440
severe medical illness complicating cesarean section.the care of the perioperative cesarean birth patient who has serious medical illnesses has changed in the past decade. the increasing sophistication of monitoring has allowed the obstetrician and anesthesiologist better to modify certain physiologic parameters that are important in the care of the patient whose physiology has been altered by surgery or disease. as an increasing segment of the obstetric population becomes older, and with better survival of medical diseases, the profession as a wh ...20113067176
preliminary observations on alterations in prolactin, gonadotropins, e2-17b & progesterone in patients with breast cancer. 20113131240
t-lymphocytes subpopulation before and after surgical removal of hepatocellular carcinoma.this study included 16 histologically confirmed hepato-cellular carcinoma (hcc) patients. at the same time, 32 normal healthy individuals and 20 asymptomatic hepatitis b surface antigen (hbsag) carriers were served as control groups. the study disclosed that t cells, okt4 cells and the ratio of okt4 cells/okt8 cells in peripheral venous blood of hcc patients before surgery were lower than that of either normal control or asymptomatic hbsag carriers. the difference was statistically significant. ...20103028718
t-lymphocytes subpopulation before and after surgical removal of hepatocellular carcinoma.this study included 16 histologically confirmed hepato-cellular carcinoma (hcc) patients. at the same time, 32 normal healthy individuals and 20 asymptomatic hepatitis b surface antigen (hbsag) carriers were served as control groups. the study disclosed that t cells, okt4 cells and the ratio of okt4 cells/okt8 cells in peripheral venous blood of hcc patients before surgery were lower than that of either normal control or asymptomatic hbsag carriers. the difference was statistically significant. ...20103028718
atrophy of the left hepatic lobe caused by a cholangiocarcinoma. 20102982248
mitochondrial protein import: involvement of the mature part of a cleavable precursor protein in the binding to receptor sites.the precursor of f0-atpase subunit 9 was bound to mitochondria in the absence of a mitochondrial membrane potential (delta psi). binding was mediated by a protease-sensitive component on the mitochondrial surface. when delta psi was reestablished, bound precursor was directly imported without prior release from the mitochondrial membranes. a chimaeric protein consisting of the complete subunit 9 precursor fused to cytosolic dihydrofolate reductase (dhfr) was also specifically bound to mitochondr ...20102892669
fun and games in urology. 20102938562
activities in nursing ethics: local, national, international. 20102876421
age-dependent changes in murine protein kinase and protease enzymes.hormone responsiveness is mediated by signal transduction mechanisms involving second messengers, such as camp and ca2+, which regulate reversible changes in the phosphorylation state of proteins. during senescence individuals frequently exhibit a diminished responsiveness to hormones. we examined changes in enzymes involved in protein phosphorylation reactions that might account for this decreased adaptiveness in old mice, and observed the following post-maturational changes: (1) camp-dependent ...20102852280
reduced hypothalamic somatostatin and neuropeptide y concentrations in the spontaneously-diabetic chinese hamster.hypothalamic concentrations of six regulatory peptides having central effects on appetite and/or glucoregulation were measured by radioimmunoassay in spontaneously-diabetic chinese hamsters and in age- and sex-matched non-diabetic control animals. in the diabetic hamsters, hypothalamic concentrations of somatostatin and neuropeptide y were significantly reduced by 25-30% below controls. none of the other four peptides examined (bombesin, galanin, neurotensin and vasoactive intestinal peptide) di ...20102905691
ouabain-resistant mutants of chinese hamster ovary cells are not directly affected in na+, k+-atpase.the nature of biochemical lesions in a number of independent single-step ouabain-resistant (ouar) mutants of chinese hamster ovary cells has been examined. the cellular uptake of 86rb in the mutant cells was found to be resistant to inhibition by ouabain and correlated with the degree of resistance of the mutants to the drug. however, the plasma membrane na+, k+-atpase from all five of the ouar mutants examined showed similar sensitivity to inhibition by ouabain as seen for the enzyme from the p ...20103016917
characterization of dimethylnitrosamine-induced focal and nodular lesions in the livers of newborn mice.newborn swiss-webster mice were given an intraperitoneal injection of 25 micrograms of dimethylnitrosamine. at weaning they began receiving 0.05% phenobarbital in the drinking water to promote the lesions for the term of the study. preneoplastic foci and hyperplastic nodules were identified histologically by two markers, resistance to exogenous iron accumulation and an increase in gamma-glutamyltranspeptidase activity. at 8, 12, and 16 weeks of age, livers of affected male mice exhibited 12, 18, ...20102863866
rings, dicentrics, and telomeric association in histiocytomas.we report clonal karyotypic abnormalities in six of 12 cytogenetically investigated malignant fibrous histiocytomas. four of eight tumors of the pleomorphic subtype had complex clonal chromosome aberrations, including ring chromosomes, dicentric chromosomes, and/or telomeric associations. no common characteristic aberration could be distinguished. two of four myxoid tumors had clonal changes: one had one to two ring chromosomes and an extra chromosome #2; another had a supernumerary ring chromos ...20102825965
neurothermography.neurothermography is a new, clinically useful method of detecting autonomic sympathetic peripheral nerve dysfunction. body symmetry of the skin temperature as maintained by symmetrically functional peripheral nerves is the key to detecting a normal state. persistent 1 degree c temperature asymmetry in the pattern of a peripheral nerve (thermatome) is a highly reliable method of detecting autonomic peripheral nerve disorder.20102845550
cigarette smoking and down syndrome.a matched case-control study of 100 mothers of down syndrome children, 100 mothers of children with other defects (defect controls), and 100 mothers of children with no defects (normal controls) was carried out. all infants were born in upstate new york in 1980 and 1981. matching was very close on maternal age for the normal controls but not for the defect controls. the risk ratios for the association of cigarette smoking around the time of conception with down syndrome was 0.58 (90% confidence ...20102934980
an assessment guide for community health nurses.an assessment tool based on the omaha classification system broadens the focus of nursing diagnosis to encompass the cultural and sociological aspects of each area of patient assessment.20102793509
heterotrophic nitrogen removal by providencia rettgeri strain yl.providencia rettgeri strain yl was found to be efficient in heterotrophic nitrogen removal under aerobic conditions. maximum removal of nh(4) (+)-n occurred under the conditions of ph 7 and supplemented with glucose as the carbon source. inorganic ions such as mg(2+), mn(2+), and zn(2+) largely influenced the growth and nitrogen removal efficiency. a quantitative detection of nitrogen gas by gas chromatography was conducted to evaluate the nitrogen removal by strain yl. from the nitrogen balance ...201020333440
[remote (2-3 years) results in patients with pulmonary tuberculosis treated in operational conditions in combination with sinerdol-eh]. 20102825331
ontogeny of mhc-linked, t cell-mediated suppression is regulated by the t cell genotype.regulation of t cell effector functions by major histocompatibility complex (mhc) gene products has been extensively researched. investigations in this area have established several important concepts of immunobiology. first, genes within the i-region of the mhc profoundly affect development of immune responses through their effects on cell-cell interactions. in the course of analyzing antigen-induced t cell activation, investigators identified specific ir-genes by demonstrating that certain str ...20102855403
technique for measurement of one-dimensional instantaneous ablation velocity.an oscillating mirror scanned a he-ne laser beam along the length of a thin rod while the rod was ablated by an argon laser beam. the shadow of the scanning beam on an image plane provides a picture of the instantaneous ablation velocity of the rod. this configuration provides a unique method for investigating one-dimensional ablation.20102976448
distribution and morphology of somatostatin cells. 20102863943
genotype and gene expression associations with immune function in drosophila.it is now well established that natural populations of drosophila melanogaster harbor substantial genetic variation associated with physiological measures of immune function. in no case, however, have intermediate measures of immune function, such as transcriptional activity of immune-related genes, been tested as mediators of phenotypic variation in immunity. in this study, we measured bacterial load sustained after infection of d. melanogaster with serratia marcescens, providencia rettgeri, en ...201020066029
volatiles emitted from eight wound-isolated bacteria differentially attract gravid screwworms (diptera: calliphoridae) to oviposit.bovine blood inoculated with bacteria isolated from screwworm [cochliomyia hominivorax (coquerel) (diptera: calliphoridae)]-infested animal wounds was tested as an attractant for oviposition for gravid screwworms. eight species of gram-negative coliform (enterobacteriaceae) bacteria mixed with bovine blood singly or all species combined and incubated for various times produced volatiles that attracted gravid flies in a cage bioassay in varying numbers. in 15-min duration tests, volatiles from fi ...201020496582
female and male genetic contributions to post-mating immune defence in female drosophila melanogaster.post-mating reduction in immune defence is common in female insects, and a trade-off between mating and immunity could affect the evolution of immunity. in this work, we tested the capacity of virgin and mated female drosophila melanogaster to defend against infection by four bacterial pathogens. we found that female d. melanogaster suffer post-mating immunosuppression in a pathogen-dependent manner. the effect of mating was seen after infection with two bacterial pathogens (providencia rettgeri ...201020573620
phylogenetic analysis of the genera proteus, morganella and providencia by comparison of rpob sequences of type and clinical strains suggests the classification of proteus myxofaciens in a new genus cosenzaea gen. nov., as cosenzaea myxofaciens comb. nov.phylogenetic analysis of partial rpob gene sequences of type and clinical strains belonging to different 16s rrna gene-fingerprinting ribogroups within 11 species of enterobacteria of the genera proteus, morganella, and providencia allowed to define rpob clades supported by high bootstrap values and confirmed by >/=2.5% nucleotide divergence. no rpob clade included strains belonging to different species and the majority of the species were confirmed as discrete and homogeneous, since they consti ...201020709916
alimentary tract bacteria isolated and identified with api-20e and molecular cloning techniques from australian tropical fruit flies, bactrocera cacuminata and b. tryoni.bacteria were isolated from the crop and midgut of field collected bactrocera cacuminata (hering) and bactrocera tryoni (froggatt) (diptera: tephritidae). two methods were used, firstly isolation onto two types of bacteriological culture media (pyea and tsa) and identification using the api-20e diagnostic kit, and secondly, analysis of samples using the 16s rrna gene molecular diagnostic method. using the api-20e method, 10 genera and 17 species of bacteria in the family enterobacteriaceae were ...201020883132
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