Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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african and asian mitochondrial dna haplogroups confer resistance against diabetic stresses on retinal pigment epithelial cybrid cells in vitro. | diabetic retinopathy (dr) is the most common cause of blindness for individuals under the age of 65. this loss of vision can be due to ischemia, neovascularization, and/or diabetic macular edema, which are caused by breakdown of the blood-retina barrier at the level of the retinal pigment epithelium (rpe) and inner retinal vasculature. the prevalence of diabetes and its complications differ between caucasian-americans and certain minority populations, such as african-americans and asian-american ... | 2020 | 31811564 |
improved foot-and-mouth disease vaccine with o panasia-2 strain protect pigs against o/jincheon/skr/2014 originated from south korea. | efforts are required to develop foot-and-mouth disease (fmd) vaccines in asia that can respond to the type o outbreaks that have continued with the devastating damage since 2010. it is necessary to develop vaccine strains that can provide protection against the me-sa topotype, which has tended to spread into neighboring areas, and the frequent sea topotype outbreaks. to this end, this study aimed to develop a fmd vaccine utilizing o panasia-2 that is able to provide broad protection against me-s ... | 2020 | 31810782 |
integrated assessment of climate change impacts on multiple ecosystem services in western switzerland. | climate change can affect the provision of ecosystem services in various ways. in this study, we provide an integrated assessment of climate change impacts on ecosystem services, considering uncertainties in both climate projection and model parameterization. the swat model was used to evaluate the impacts on water regulation, freshwater, food, and erosion regulation services for the broye catchment in western switzerland. downscaled euro-cordex projections were used for three periods of thirty ... | 2020 | 31810703 |
economic value of adjunctive brivaracetam treatment strategy for focal onset seizures in finland. | there is an unmet need for well-tolerated antiepileptic drugs (aeds) that effectively control focal onset seizures. this study aimed to evaluate the economic value of new aeds in the treatment of focal onset seizure, with or without secondary generalization, in finnish adults and adolescents with epilepsy, comparing brivaracetam with perampanel as adjunctive aeds. | 2020 | 31808053 |
metaphors and cultural narratives on adaptive responses to severe adversity: a field study among the indigenous pitaguary community in brazil. | the expressions resilience and posttraumatic growth represent metaphorical concepts that are typically found in euro-american contexts. metaphors of severe adversity or trauma and the expressions of overcoming it vary across cultures-a lacuna, which has not been given much attention in the literature so far. this study aimed to explore the metaphorical concepts that the indigenous pitaguary community in brazil uses to talk about adaptive and positive responses to severe adversity and to relate t ... | 2020 | 31795874 |
diversified lineages and drug-resistance profiles of clinical isolates of mycobacterium tuberculosis complex in malaysia. | tuberculosis (tb) is still a major health problem in malaysia with thousands of cases reported yearly. this is further burdened with the emergence of multidrug-resistant tb (mdr-tb). whole-genome sequencing (wgs) provides high-resolution molecular epidemiological data for the accurate determination of mycobacterium tuberculosis complex (mtbc) lineages and prediction of the drug-resistance patterns. this study aimed to investigate the diversity of mtbc in malaysia in terms of lineage and drug-res ... | 2020 | 31793500 |
burdens of the scientific revolution: euro/west-centrism, black boxed machines, and the (post) colonial present. | how is it possible that past technoscientific research in india does not serve as a sluice for circulations of technoscience even within india? why do technoscientific artifacts and knowledge continue to flow largely through the west? the answer to these and related questions, i argue, lies in the entanglement of technoscientific practices in india with orientalist historiography of the origin of modern science. such an orientalist construction forms the basis of the diffusion model and constitu ... | 2020 | 31761793 |
platinum group elements study in automobile catalysts and exhaust gas samples. | platinum-group elements (pges, i.e. platinum; pt, palladium; pd and rhodium; rh) are extensively employed in the production of automotive catalytic converters to catalyze and control harmful emissions from exhaust fumes. but catalytic converters wear out over time and the emission of pges along with the exhaust fumes are nowadays known to be the main reason of the presence of pges in urban environments. pges contents were studied on three gasoline 3-way catalytic convertors with low, medium and ... | 2020 | 31761587 |
the impact of liver fluke infection on steers in ireland: a meta-analytic approach. | post-mortem liver inspection results together with production parameters are often used to estimate the impact of liver fluke infection on farm animal populations. however, post mortem liver inspection is an imperfect method of determining the liver fluke infection status of cattle. this work estimates the difference in mean lifetime weight gain at 819 days (δlwg819) between steers assigned liver fluke negative (lfn) and liver fluke positive (lfp) status at post-mortem meat inspection, quantifie ... | 2020 | 31756670 |
melatonin in neuropaediatric mri: a retrospective study of efficacy in a general hospital setting. | melatonin may offer a safe and cheap alternative to general anaesthesia and sedatives in neuropaediatric mri. the purpose of our study was to evaluate its efficacy during a daily scanning programme and to assess its financial benefit. | 2020 | 31753707 |
the ongoing cut-down of the amazon rainforest threatens the climate and requires global tree planting projects: a short review. | the amazon rainforest has sustained human existence for more than 10,000 years. part of this has been the way that the forest controls regional climate including precipitation important for the ecosystem as well as agroforestry and farming. in addition, the amazon also affects the global weather systems, so cutting down the rainforest significantly increases the effects of climate change, threatening the world's biodiversity and causing local desertification and soil erosion. the current fire ac ... | 2020 | 31732170 |
cost-effectiveness of an exercise and nutritional intervention versus usual nutritional care during adjuvant treatment for localized breast cancer: the pasapas randomized controlled trial. | we undertook a cost-effectiveness analysis (cea) to compare an exercise and nutritional program with the usual nutritional care concomitant to adjuvant chemotherapy in localized breast cancer patients. the cea was designed as part of the interventional, controlled, randomized, single-center, open-label pasapas study. breast cancer patients receiving first-line adjuvant chemotherapy at a french comprehensive cancer center were randomized 2:1 to a 6-month exercise program of supervised indoor and ... | 2020 | 31729566 |
employment status and personal income before and after onset of a severe mental disorder: a case-control study. | individuals with severe mental disorders have an impaired ability to work and are likely to receive income transfer payments as their main source of income. however, the magnitude of this phenomenon remains unclear. using longitudinal population cohort register data, the authors conducted a case-control study to examine the levels of employment and personal income before and after a first hospitalization for a serious mental disorder. | 2020 | 31722646 |
stable isotopes from the african site of elmina, ghana and their usefulness in tracking the provenance of enslaved individuals in 18th- and 19th-century north american populations. | stable isotope values for historic period human remains from elmina, ghana, are compared to isotope data from 18th- and 19th-century north american sites as a test case for examining african origins and identifying first generation africans in the mid-atlantic region of the united states. | 2020 | 31688955 |
corrigendum to: clinical presentation, aetiology and outcome of infective endocarditis. results of the esc-eorp euro-endo (european infective endocarditis) registry: a prospective cohort study. | 2020 | 31682254 | |
medium-term outcome of posterior surgery in the treatment of non-tuberculous bacterial spinal infection. | to evaluate the outcome of posterior spinal stabilization surgery for the management of bacterial spinal infection. | 2020 | 31680747 |
changes in health-related quality of life are associated with patient satisfaction following total hip replacement: an analysis of 69,083 patients in the swedish hip arthroplasty register. | background and purpose - total hip replacement (thr) aims mainly to improve quality of life via restoration of hip function and provision of pain relief. this study sought to assess whether improvements in quality of life between the preoperative and 1-year postoperative period were associated with patient satisfactionpatients and methods - data were extracted for 69,083 thr operations with complete data reported to the swedish hip arthroplasty register (shar) between 2008 and 2015. health-relat ... | 2020 | 31680594 |
impact of ssb taxes on sales. | in this paper, we analyze a tax on sugar-sweetened beverages (ssb) that was introduced in catalonia on may 1, 2017. the bill established the requirement of a 100% pass-through of the tax to the final consumer and two levels of the tax: 0.08 euro/liter for products with 5-less than 8 g of sugar and 0.12 euro/liter for products with 8 g of sugar or more. previous literature focusing on the impact of ssb taxes finds that pass-though is only complete in the long-term. our paper provides new evidence ... | 2020 | 31654894 |
lyme snap: a feasibility study of on-line declarations of erythema migrans in a rural area of france. | the incidence of lyme borreliosis remains a matter of debate, but it can be estimated using the incidence of erythema migrans (em), which is pathognomonic of the first phase. the aim of this prospective pilot study was to assess the feasibility of the on-line declaration of em in rural areas where the incidence of lyme borreliosis was previously estimated at 85 per 100,000 inhabitants per year. the study was limited to a rural area (les combrailles, auvergne) of approximately 52,800 inhabitants ... | 2020 | 31653585 |
changes in depressive symptoms of older adults in the czech republic. | it is unclear whether the rising burden of depression is due to its increasing prevalence or better detection. we aimed to study trends in depressive symptoms in older individuals from the czech republic. | 2020 | 31627114 |
understanding the patient profile and health-related quality of life in patients presenting for hand surgery. | the aim of this descriptive epidemiological study of patients, referred to and selected for surgery at a uk tertiary hand centre, was to investigate patterns of common hand disorders and their impact on those individuals. a prospective collection of patient-reported outcome scores was carried out in patients before operation using the patient outcomes of surgery hand/arm and the euro-qol 5 dimension three-level measures. patient participation was voluntary and data collected over a 4-year period ... | 2020 | 31619128 |
benefit-cost analysis of the danish sun safety campaign 2007-2015: cost savings from sunburn and sunbed use reduction and derived skin cancer reductions 2007-2040 in the danish population. | ninety percent of skin cancers are avoidable. in denmark, 16,500 cases of melanoma and keratinocyte cancers were registered in 2015. the danish sun safety campaign has campaigned since 2007, targeting overexposure to ultraviolet radiation. during 2007-2015, the key indicators of skin cancer, i.e. sunbed use and sunburn, showed annual reductions of 6% and 1%, respectively. | 2020 | 31617085 |
the association between, depression, anxiety, and mortality in older people across eight low- and middle-income countries: results from the 10/66 cohort study. | depression and anxiety are common mental disorders in later life. few population-based studies have investigated their potential impacts on mortality in low- and middle-income countries (lmics). the aim of this study is to examine the associations between depression, anxiety, their comorbidity, and mortality in later life using a population-based cohort study across eight lmics. | 2020 | 31608478 |
fluorescence-based cholangiography: preliminary results from the ihu-ircad-eaes euro-figs registry. | near-infrared fluorescence cholangiography (nirf-c) is a popular application of fluorescence image-guided surgery (figs). nirf-c requires near-infrared optimized laparoscopes and the injection of a fluorophore, most frequently indocyanine green (icg), to highlight the biliary anatomy. it is investigated as a tool to increase safety during cholecystectomy. the european registry on figs (euro-figs: www.euro-figs.eu ) aims to obtain a snapshot of the current practices of figs across europe. data on ... | 2020 | 31591654 |
the use of a gentamicin-coated titanium nail, combined with ria system, in the management of non-unions of open tibial fractures: a single centre prospective study. | nonunion is a quite common complication of open tibial shaft fractures. this prospective case series investigates the use of the gentamicin-coated titanium intramedullary tibial nail, in association with the ria system, in patients with tibial exposed nonunions. | 2020 | 31591005 |
[food policies to prevent obesity and the main non-transmissible diseases in spain: where there's a will there's a way]. | in spain, one third of all children and two-thirds of adults suffer from excess weight, a condition that generates a direct excess medical cost of 2000 million euros. obesogenic food environments cause obesity by promoting the consumption of sugar-sweetened beverages and ultra-processed foods. accordingly, we propose five priority policies capable of reversing the epidemic of obesity and related non-communicable diseases through the creation of healthy food environments. | 2020 | 31585770 |
which factors are associated with local control and survival of patients with localized pelvic ewing's sarcoma? a retrospective analysis of data from the euro-ewing99 trial. | local treatment of pelvic ewing's sarcoma may be challenging, and intergroup studies have focused on improving systemic treatments rather than prospectively evaluating aspects of local tumor control. the euro-ewing99 trial provided a substantial number of patients with localized pelvic tumors treated with the same chemotherapy protocol. because local control included surgical resection, radiation therapy, or a combination of both, we wanted to investigate local control and survival with respect ... | 2020 | 31580267 |
how do we process prices? electrophysiological evidence of componential analysis. | the aim of this study was to evaluate if the processing of prices (e.g., 8 euro) involves separate analysis of the digit (8) and the monetary category (euro). event-related potentials (erps) were recorded when participants performed a price comparison task in which a pair of prices was presented and they selected the one with higher monetary value. there were compatible comparisons where the digit and the monetary category of one price were higher than those of the other price (e.g., 7 euro - 4 ... | 2020 | 31553072 |
patellofemoral pain: one year results of a randomized trial comparing hip exercise, knee exercise, or free activity. | extended follow-up of a randomized trial comparing hip-focused exercise, knee-focused exercise, and free physical activity in patellofemoral pain (pfp). | 2020 | 31846113 |
validity of the japanese core outcome measures index (comi)-back for thoracic and lumbar spine surgery: a prospective cohort study. | to investigate the psychometric properties of the japanese version of the core outcome measures index-back (comi-back), only recently published according to the established linguistic and cultural conversion guidelines, in patients undergoing spine surgery. | 2020 | 31845032 |
[what is an efficient health intervention in spain in 2020?] | fifteen years ago, gaceta sanitaria published the article entitled "what is an efficient health technology in spain?" the growing interest in setting the price of new technologies based on the value they provide to health systems and the experience accumulated by the countries in our environment make it opportune to review what constitutes an efficient health intervention in spain in 2020. cost-effectiveness analysis continues to be the reference method to maximize social health outcomes with th ... | 2020 | 31558385 |
the u.s.-forta (fit for the aged) list: consensus validation of a clinical tool to improve drug therapy in older adults. | polypharmacy and multimorbidity is a threat to older people; hence, listing approaches should support physicians to optimize medication. the forta (fit for the aged) classification of drug appropriateness for older people provides positive or negative labels: a (a-bsolutely), b (b-eneficial), c (c-areful), and d (d-on't). based on these categories, forta-labeled drug lists were developed in 7 european countries or regions; the same approach was used to develop a u.s.-forta list reflecting the co ... | 2020 | 31542300 |
measurement invariance of the five factor model of personality: facet-level analyses among euro and asian americans. | relative to broad big five domains, personality facets provide incremental value in predicting life outcomes. valid between-group comparisons of means and correlates of facet scores are contingent upon measurement invariance of personality measures. research on culture and big five personality has been largely limited to cross-national comparisons of domains, without assessing measurement invariance across ethnoracial groups within the same country. using the neo inventories, we tested facet-lev ... | 2020 | 31535567 |
a retrospective study of childhood sex-typed behavior in istmo zapotec men, women, and muxes. | previous research has consistently demonstrated that both transgender and cisgender androphilic males (i.e., males attracted to adult males) display and recall higher levels of childhood female-typical behavior (cftb) and lower levels of childhood male-typical behavior (cmtb) compared to gynephilic males (i.e., males attracted to adult females). in adulthood, the recalled cftb and cmtb scores of cisgender androphilic males tend to be intermediate to those of opposite-sex-attracted men and women, ... | 2020 | 31529223 |
occurrence and synoptic background of strong and very strong frost in spring and autumn in central europe. | the objective of the paper was the determination of the circulation conditions of occurrence of strong and very strong frost in central europe. a frost day was defined as a day with the minimum temperature lower than 0 °c and maximum temperature higher than 0 °c. moreover, a division of frost was performed in terms of value of minimum temperature, resulting in the designation of mild frost (up to - 2.0 °c), moderate frost (from - 2.1 to - 4 °c), strong frost (from - 4.1 to - 6 °c) and very stron ... | 2020 | 31515610 |
transcriptome characterization and expression profiling in chestnut cultivars resistant or susceptible to the gall wasp dryocosmus kuriphilus. | the oriental gall wasp dryocosmus kuriphilus represents a limiting pest for the european chestnut (castanea sativa, fagaceae) as it creates severe yield losses. the european chestnut is a deciduous tree, having major social, economic and environmental importance in southern europe, covering an area of 2.53 million hectares, including 75,000 ha devoted to fruit production. cultivars show different susceptibility and very few are resistant to gall wasp. to deeply investigate the plant response and ... | 2020 | 31506717 |
impacts on human mortality due to reductions in pm10 concentrations through different traffic scenarios in paris, france. | air pollution is a well-known burden for population health and health systems worldwide. reduction in air pollution is associated with improvements in mortality and rates of respiratory, cardiovascular and other diseases. though air quality is a problem globally, efforts to lower air pollutant concentrations are usually regional or local. in industrialized countries, most urban air pollution is caused by vehicles, suggesting reductions in traffic would result in reductions of pollution. however, ... | 2020 | 31494426 |
alcohol septal ablation in patients with severe septal hypertrophy. | the current guidelines suggest alcohol septal ablation (asa) is less effective in hypertrophic obstructive cardiomyopathy (hocm) patients with severe left ventricular hypertrophy, despite acknowledging that systematic data are lacking. therefore, we analysed patients in the euro-asa registry to test this statement. | 2020 | 31471463 |
[the cost of the therapeutic education program "eat better, move more through nutrition education" in patients with breast cancer]. | since the life expectancy of women with breast cancer has increased, tertiary prevention, through the therapeutic patient education (tpe), is now a part of patient support. the main objective of this pilot study is to evaluate the cost of a nutrition and physical activity tpe program intended to help women with breast cancer in the management of their weight. | 2020 | 33012504 |
grip strength and depression symptoms among middle-age and older adults. | to analyze the relationship between grip strength and symptoms of depression, considering sex and age, in adults from 18 countries. | 2020 | 33012344 |
impaired kidney function is associated with lower quality of life among community-dwelling older adults : the screening for ckd among older people across europe (scope) study. | quality of life (qol) refers to the physical, psychological, social and medical aspects of life that are influenced by health status and function. the purpose of this study was to measure the self-perceived health status among the elderly population across europe in different stages of chronic kidney disease (ckd). | 2020 | 33008306 |
resolved: expression of concern for euro surveill. 2020;25(32). | 2020 | 33006304 | |
authors' correction for euro surveill. 2020;25(32). | 2020 | 33006302 | |
long term follow-up and optimization of infliximab in refractory uveitis due to behçet's disease. national study of 103 caucasian patients. | in a large series of caucasian patients with refractory uveitis due to behçet disease (bd) treated with infliximab (ifx) we assessed: a) long-term efficacy and safety and b) ifx optimization when ocular remission was achieved. | 2020 | 33004539 |
sarcopenia aneurysm scoring system predicts early and midterm mortality after endovascular repair for abdominal aortic aneurysm. | the objective of the study was to develop a better model of prediction after evar using the psoas muscle index (pmi). | 2020 | 33002942 |
a multi-country dynamic factor model with stochastic volatility for euro area business cycle analysis. | this paper develops a dynamic factor model that uses euro area country-specific information on output and inflation to estimate an area-wide measure of the output gap. our model assumes that output and inflation can be decomposed into country-specific stochastic trends and a common cyclical component. comovement in the trends is introduced by imposing a factor structure on the shocks to the latent states. we moreover introduce flexible stochastic volatility specifications to control for heterosc ... | 2020 | 32999523 |
cross-sectional and prospective relationship between physical activity and depression symptoms. | this study aimed to analyse the cross-sectional and prospective relationship between moderate and vigorous physical activity (pa) and depression symptoms. this study analysed 32,392 european late middle-aged to older adults, from 14 european countries across a 4-year follow-up. data was collected in the fourth (in 2011) and sixth (in 2015) wave, from the survey of health, ageing and retirement in europe (share). for the present analysis, participants were considered who responded to the euro-d 1 ... | 2020 | 32999306 |
canadian real-world experience of using sacubitril/valsartan in patients with heart failure with reduced ejection fraction: insight from the parasail study. | to determine the effectiveness of sacubitril/valsartan 97/103 mg twice daily (b.i.d.) on tolerability, safety, and quality of life (qol) in canadian patients with heart failure with reduced ejection fraction in a real-life setting. | 2020 | 32995719 |
comparison of the reverse bevel versus franseen type endoscopic ultrasound needle. | reverse bevel (rb) needle is widely used for endoscopic ultrasound fine needle biopsy (eus-fnb). a 3-plane symmetrical needle with franseen geometry (fg) has recently become available. | 2020 | 32994857 |
psychiatric, cognitive functioning and socio-cultural views of menstrual psychosis in oman: an idiographic approach. | most documented cases of menstrual psychosis have been from euro-american populations with reports from cross-cultural populations being only a few. a primary aim was to determine whether the cyclical/episodic nature of menstrual psychosis among case series observed at a tertiary care unit in oman fulfills the diagnostic criteria of the international classification of diseases (icd-10) and diverge into brockington's sub-types (world psychiatry. 2005;4(1):9-17). related aims were to solicit measu ... | 2020 | 32993616 |
brown sugar, how come you taste so good? the impact of a soda tax on prices and consumption. | increasing obesity-related problems and rising healthcare expenditures have led governments in developed countries to consider the introduction of soda taxes. we study a recent such tax, implemented in portugal in february 2017 -one of the first soda taxes worldwide that increases with sugar content (0.08 euros per liter for drinks with less than 80 g of sugar per liter, and 0.16 euros per liter for drinks with 80 g or more sugar per liter, plus vat). we use extremely detailed panel data from on ... | 2020 | 32992226 |
[exercise behavior, costs of physical inactivity, and physical activity promotion in austria]. | in this article, we present the austrian data on physical activity, the societal costs and outcomes of physical inactivity, and the areas of influence to promote physical activity. based on an analysis of the status quo and its consequences, suggestions on relevant measures to counter physical inactivity are made. while the proportion of austrians that do not fulfill the current recommendations on physical activity is high, the austrian population is physically more active than many populations ... | 2020 | 32984943 |
a time-frequency analysis of the impact of the covid-19 induced panic on the volatility of currency and cryptocurrency markets. | we apply wavelet analyses to examine the impact of the covid-19 fueled panic on the volatility of major fiat and cryptocurrency markets during january-may, 2020. there is high coherence between moves of the coronavirus panic index and the price moves in euro, british pound, and renminbi currencies as well as movements of the bloomberg galaxy crypto index. the main conclusions for each index pair are quite similar and corroborate with our thesis that the cross-currency hedge strategies, which cou ... | 2020 | 32983899 |
single nucleotide polymorphism in kir2dl1 is associated with hla-c expression in global populations. | regulation of nk cell activity is mediated through killer-cell immunoglobulin-like receptors (kir) ability to recognize human leukocyte antigen (hla) class i molecules as ligands. interaction of kir and hla is implicated in viral infections, autoimmunity, and reproduction and there is growing evidence of the coevolution of these two independently segregating gene families. by leveraging kir and hla-c data from 1000 genomes consortium we observed that the kir2dl1 variant rs2304224*t is associated ... | 2020 | 32983108 |
editorial: or for sustainable development. | the presented issue concerns publications presented as part of the workshop 2018 of the euro working group on operational research for development (ewg-ord) held in complutense university of madrid (spain), july 5-7. this editorial presents an introduction on sustainable development and the sustainable development goals. it contains short descriptions of the research area presented in individual publications, highlighting their contributions to the achievement of the sustainable development goal ... | 2020 | 32982578 |
analysis of the health and budgetary impact of chondroitin sulfate prescription in the treatment of knee osteoarthritis compared to nsaids and coxibs. | chondroitin sulfate, alone or associated with glucosamine (cs), is an effective treatment of osteoarthritis, better tolerated than non-steroidal anti-inflammatory drugs (nsaids) and cyclooxygenase 2 inhibitors (coxibs) at gastrointestinal, cardiovascular and renal levels. | 2020 | 32982340 |
cost and burden of poor anticoagulation control with vitamin k antagonists in patients with nonvalvular atrial fibrillation in spain. | the aim of this analysis was to evaluate the burden and cost of complications due to poor anticoagulation control in patients with nonvalvular atrial fibrillation (nvaf) treated with vitamin k antagonists (vka) in spain. | 2020 | 32980294 |
the association of grip strength with depressive symptoms among middle-aged and older adults with different chronic diseases. | low grip strength has been associated with an increase in depressive symptoms, independent of age group or gender, although the literature has not investigated this association among different chronic diseases. the present study aims to investigate the association of grip strength and depressive symptoms among middle-aged and older adults with different chronic diseases. a cross-section of data from the survey of health, ageing, and retirement in europe wave 6 (collected in 2015) was analysed. g ... | 2020 | 32977410 |
[registry research funding of the german society of plastic, reconstructive and aesthetic surgeons (dgpräc) and research funding report 2019/2020]. | since 2015/16 the dgpräc collects, evaluates and publishes the research activities of academic sections, departments and clinics for plastic surgery at university hospitals in germany, in order to raise the awareness of plastic surgical research performance. | 2020 | 32977347 |
authors' correction for euro surveill. 2020;25(36). | 2020 | 32975185 | |
potential cost-savings from the use of the biosimilars in slovakia. | objectives: to analyse the market shares of biosimilars in slovakia and to calculate the potential cost-savings from the use of biosimilars in slovakia based on two different data sources. methods: national reimbursement lists from the czech republic, hungary, poland and slovakia were used for analyzing the availability of biosimilars with public funding. in addition, the reimbursement dossiers of biosimilars, the justifications of reimbursement decisions by the slovak ministry of health, and fi ... | 2020 | 32974261 |
can we predict outcome after treatment of long bone osteomyelitis? | this study presents patient-reported quality of life (qol) over the first year following surgical debridement of long bone osteomyelitis. it assesses the bone involvement, antimicrobial options, coverage of soft tissues, and host status (bach) classification as a prognostic tool and its ability to stratify cases into 'uncomplicated' or 'complex'. | 2020 | 32967461 |
the role of birds of prey in west nile virus epidemiology. | reported human cases of west nile virus (wnv) in europe increased dramatically in 2018. lineage 1 strains had been circulating in euro-mediterranean countries since the early 1990s. the subsequent introduction of wnv lineage 2 has been responsible for the remarkable upsurge of european wnv outbreaks since 2004, including the dramatic increase in human cases observed since 2018. the virus exists in a natural cycle between mosquitoes and wild birds, with humans and horses acting as dead-end hosts. ... | 2020 | 32967268 |
pollen viability of euro-mediterranean orchids under different storage conditions: the possible effects of climate change. | the future impact of climate change and a warmer world is a matter of great concern. we therefore aimed to evaluate the effects of temperature on pollen viability and fruit set of mediterranean orchids. the in vitro and controlled pollination experiments were performed to evaluate the ability of pollinia stored at lower and higher temperatures to germinate and produce fruits and seeds containing viable embryos. in all of the examined orchids, pollen stored at -20 °c remained fully viable for up ... | 2020 | 32967048 |
investigation of esthetic evaluation and its influencing factors for a tunnel portal based on dynamic vision. | with the development of modern cities, roads, and landscapes, it is becoming increasingly important for infrastructure such as tunnels to provide an esthetically pleasing experience. in this respect, it is necessary to conduct studies that consider the esthetic design of tunnel portals using esthetics research. regarding the esthetic evaluation of tunnel portals, this paper fully considers the dynamic visual effect from the driver's perspective. this study combines the use of blender, speedtree ... | 2020 | 32966282 |
nutritional quality, child-oriented marketing and health/nutrition claims on sweet biscuit, breakfast cereal and dairy-based dessert packs in argentina. | as children are particularly vulnerable to marketing, this study analyzes marketing techniques and health/nutrition claims in food packaging and evaluates the nutritional quality in three food categories: sweet biscuits, breakfast cereals and dairy-based desserts. this descriptive study analyzed marketing techniques and claims included in food packaging (n = 301) in one of the largest retailers in argentina. trained researchers coded data following an adapted version of the informas protocol to ... | 2020 | 32965379 |
predictability analysis of the pound's brexit exchange rates based on google trends data. | during the last decade, the use of online search traffic data is becoming popular in examining, analyzing, and predicting human behavior, with google trends being a popular tool in monitoring and analyzing the users' online search patterns in several research areas, like health, medicine, politics, economics, and finance. towards the direction of exploring the sterling pound's predictability, we employ google trends data from the last 5 years (march 1st, 2015 to february 29th, 2020) and perform ... | 2020 | 32963933 |
longitudinal associations between specific symptoms of depression: network analysis in a prospective cohort study. | network perspective to mental disorders suggests that depression develops due to interrelated associations between individual symptoms rather than due to a common cause. however, it is unclear whether long-term longitudinal associations between specific symptoms of depression demonstrate coherent patterns. we examined the temporal sequences and changes in depressive symptoms over time, and whether some symptoms are more central than others in inducing changes in the rest of the symptoms over tim ... | 2020 | 32956966 |
efficacy of learning through play plus intervention to reduce maternal depression in women with malnourished children: a randomized controlled trial from pakistan✰. | the risk factors and adverse outcomes related to maternal depression and child malnutrition are a leading cause of morbidity and mortality in low and middle-income countries (lmic) including pakistan. above 25% of women suffer from maternal depression. up to 50% children are under-nourished which contributes to 35% of all under-5 deaths in the country. | 2020 | 32956964 |
inside ilsi: how coca-cola, working through its scientific nonprofit, created a global science of exercise for obesity and got it embedded in chinese policy (1995-2015). | industry influence on health science and policy is a critical issue of our day. in 2015, the new york times revealed that coca-cola paid scientists to form a global energy balance network promoting the notion that exercise, not dietary restraint, is the solution to the obesity epidemic-a claim few accept. this article examines the organizational dynamics and policy process behind coke's efforts to sway obesity policy, globally and in china, a critical market, during 1995-2015. | 2020 | 32955566 |
translation and validation of the danish version of the zurich claudication questionnaire. | validation study. | 2020 | 32954809 |
moving closer? comparing regional adjustments to shocks in emu and the united states. | this paper analyzes alternative channels of adjustment to nominal exchange rate flexibility in response to shocks faced by countries and regions that are part of a monetary union. over our full sample period of analysis (1977-2018), the results suggest a dominant role of interstate migration as an adjustment channel to labor demand shocks for the united states. in contrast, european countries tend to adjust to negative labor demand shocks mainly through changes in labor force participation and u ... | 2020 | 32952255 |
genetic testing offer for inherited neuromuscular diseases within the euro-nmd reference network: a european survey study. | the genetic diagnostics of inherited neuromuscular diseases (nmds) is challenging due to their clinical and genetic heterogeneity. we launched an online survey within the euro-nmd european reference network (ern) to collect information about the availability/distribution of genetic testing across 61 ern health care providers (hcps). a 17 items questionnaire was designed to address methods used, the number of genetic tests available, the clinical pathway to access genetic testing, the use of next ... | 2020 | 32946487 |
early origin and global colonisation of foot-and-mouth disease virus. | in this study, we compiled 84-year worth (1934-2017) of genomic and epidemiological data of foot-and-mouth disease virus (fmdv), and performed comprehensive analyses to determine its early origin and transmission route. we found that recombination is a key feature of fmdv, and that the genomic regions coding for structural and non-structural proteins have markedly different evolutionary histories, and evolve at different rates. despite all of these differences, analyses of both structural and no ... | 2020 | 32943727 |
impact of corona virus disease 2019 on oral- and maxillofacial surgery: preliminary results after the curfew. | the covid-19 pandemic affects basic health care in maxillofacial surgery (mfs) due to the shift in resources and the change in patient disorders treated during the pandemic. this paper aims to elucidate the medical and financial consequences driven by the measures for covid-19 treatment in a tertiary care centre. | 2020 | 32941222 |
[how much does research and development of a drug cost? a call for more transparency]. | the cost of research and development (r&d) for a new medicine is an essential element in the debate about fair prices. in a recent study, we estimated r&d costs at an average of around 1.1 billion euro per drug; that is a lot of money, but more than 50% lower than the usual estimate of 2.4 billion euro. there is a need for more transparency about r&d costs, so that proposed prices for medicines can be better assessed on their fairness. | 2020 | 32940989 |
are unit costs the same? a case study comparing different valuation methods for unit cost calculation of general practitioner consultations. | to inform allocation decisions in any healthcare system, robust cost data are indispensable. nevertheless, recommendations on the most appropriate valuation approaches vary or are nonexistent, and no internationally accepted gold standard exists. this costing analysis exercise aims to assess the impact and implications of different calculation methods and sources based on the unit cost of general practitioner (gp) consultations in austria. | 2020 | 32940231 |
a critical essay on the historiography of east asian medicines: new horizons beyond dichotomy and "tradition". | one of the main topics discussed by historians, including those of science, in the late twentieth century is the historical introspection into "modernism," a term based on a teleological view of the world. according to the conventional understanding of world history, the historical process to modernity that has led to the civil revolution, scientific revolution, and capitalism is linear and universally inevitable, and this-in other words, eurocentrism-implies that only the historical experiences ... | 2020 | 32937643 |
analysis of the cost effectiveness of different strategies for the antenatal diagnosis of chromosomal aberrations in cases of ultrasound-identified fetal abnormalities. | principal objective of this work was to analyse the cost effectiveness of different sequences of cytogenetic techniques from the hospital's point of view, after prenatal ultrasound has identified fetal malformations. | 2020 | 32933889 |
psychometric properties of the casp-12 scale in portugal: an analysis using share data. | the purpose of this study is to assess the psychometric properties of the portuguese version of the control, autonomy, self-realization, and pleasure (casp)-12 scale used in the survey of health, aging and retirement in europe (share) project. data were obtained from a representative sample of 1666 people aged ≥50 years living in portugal and participating in the share wave 6. in addition to the casp-12 scale, sociodemographic data and health status, activity limitation (gali), depression (euro- ... | 2020 | 32932768 |
randomized clinical trial a novel absorbable stapler provides patient-reported outcomes and cost-effectiveness non-inferior to subcuticular skin closure: a prospective single-blinded randomized clinical trial. | deep dermal suturing is critical for scar quality outcomes. we evaluated a new fast medical device for dermal suturing, with hypothesis of non-inferiority with regard to clinical scar and cost-effectiveness. | 2020 | 32925811 |
caregivers' sense of coherence: implications on direct and indirect costs of dementia care. | dementia care is associated with physical, emotional, and monetary impact on the informal carers providing unpaid care. differences in the personal characteristics of caregivers may help explain the variations in the costs of dementia care. | 2020 | 32925037 |
adding the coping power programme to parent management training: the cost-effectiveness of stacking interventions for children with disruptive behaviour disorders. | parent management training (pmt) programmes and child cognitive behavioural therapy are recommended approaches for treatment of oppositional defiant disorder in children, and combining these may be effective. however, little is known regarding the economic efficiency of this additive effect. a within-trial cost-effectiveness analysis was carried out in sweden including 120 children aged 8-12 who screened positive for disruptive behaviour disorders, within a psychiatric care setting, and their pa ... | 2020 | 32924086 |
model-based evaluation of the microhemodynamic effects of pegylated hboc molecules in the rat brain cortex: a laser speckle imaging study. | hemoglobin-based oxygen carriers (hbocs) were developed with the aim of substituting transfusions in emergency events. however, they exhibit adverse events, such as nitric oxide (no) scavenging, vasoactivity, enhanced platelet aggregation, presently hampering their clinical application. the impact of two prototypical pegylated hbocs, euro-peg-hb and peg-hbo2, endowed by different oxygen affinities and hydrodynamic volumes, was assessed on the cerebrocortical parenchymal microhemodynamics, and ex ... | 2020 | 32923034 |
cost-utility analysis of nivolumab in adjuvant treatment of melanoma in france. | the aim of the current study is to estimate the cost-effectiveness of adjuvant treatment with nivolumab relative to clinically relevant comparators in adult patients with melanoma with lymph node involvement or metastatic disease who have undergone complete resection from a french societal perspective. | 2020 | 32920709 |
assessing impacts of future climate change on extreme fire weather and pyro-regions in iberian peninsula. | weather conditions play an important role in wildfire activity. in many regions, future climate could lead to different fire weather, with impacts on the ignition, behaviour, and suppression of wildfires, which may, therefore, force new fire regimes. this study aimed to assess the evolution of fire weather indices and the number of extreme days (ned) in the context of climate change. we estimated the impact of these changes on monthly normalized burnt area (nba) and in the spatial distribution o ... | 2020 | 32920419 |
assessing the future medical cost burden for the european health systems under alternative exposure-to-risks scenarios. | ageing populations and rising prevalence of non-communicable diseases (ncds) increasingly contribute to the growing cost burden facing european healthcare systems. few studies have attempted to quantify the future magnitude of this burden at the european level, and none of them consider the impact of potential changes in risk factor trajectories on future health expenditures. | 2020 | 32915826 |
aggregate stability under a budget rule and labor mobility. | whether a balanced budget rule stabilizes or destabilizes an economy depends on various factors such as the production function or the instrument used to balance the budget. this paper argues that migration, which has widely been neglected in the literature, also affects equilibrium properties. we study the effect of pro-cyclical labor mobility in a neoclassical growth model with public debt and a balanced budget requirement. labor mobility can destabilize the economy due to external effects. af ... | 2020 | 32905042 |
how different stressors affect quality of life: an application of multilevel latent class analysis on a large sample of industrial employees. | quality of life (qol) indicates individual's perception of the physical, psychological and social aspects of health. the association between qol and all stressful life events' dimensions has not been investigated among industrial employees. | 2020 | 32903876 |
spoligotyping of mycobacterium tuberculosis isolates using luminex®-based method in lebanon. | data about the genotypes of circulating mycobacterium tuberculosis isolates (mtb) in lebanon are scarce. this study was undertaken to reveal the spoligotypes of mtb isolates recovered from patients in lebanon. | 2020 | 32903232 |
genome-wide landscape establishes novel association signals for metabolic traits in the arab population. | while the arabian population has a high prevalence of metabolic disorders, it has not been included in global studies that identify genetic risk loci for metabolic traits. determining the transferability of such largely euro-centric established risk loci is essential to transfer the research tools/resources, and drug targets generated by global studies to a broad range of ethnic populations. further, consideration of populations such as arabs, that are characterized by consanguinity and a high l ... | 2020 | 32902719 |
ultra-short antibiotic prophylaxis guided by preoperative microbiological nasal swabs in endoscopic endonasal skull base surgery. | endoscopic endonasal skull base surgery (eesbs) is a clean-contaminated procedure. guidelines regarding the antibiotic prophylaxis in eesbs have not been developed yet, and today, there are no universally accepted protocols. in this article, we investigated the efficacy of our new ultra-short antibiotic prophylaxis protocol for eesbs guided by the cultural results of preoperative microbiological nasal swabs. | 2020 | 32901395 |
on-road nox and smoke emissions of diesel light commercial vehicles-combining remote sensing measurements from across europe. | light commercial vehicles (lcvs) account for about 10-15% of road traffic in europe. there have only been few investigations on their on-road emission performance. here, on-road remote sensing vehicle emission measurements from 18 locations across four european countries are combined for a comprehensive analysis of nox and smoke emission rates from diesel lcv in the past two decades. this allows differentiating the performance by emission standards, model years, curb weights, engine loads, manuf ... | 2020 | 32897059 |
[specialised headache units, a feasible alternative in spain]. | visits due to headaches are the most frequent cause of demand for neurological treatment in primary care and neurology services. headache units improve the quality of care, reduce waiting lists, facilitate access to new treatments of proven efficacy and optimise healthcare expenditure. however, these units have not been implemented on a widespread basis in spain due to the relatively low importance attributed to the condition and also the assumption that such units have a high cost. | 2020 | 32895902 |
breaking the bank? a probabilistic assessment of euro area bank profitability. | this paper explores the determinants of profitability across large euro area banks using an approach based on conditional profitability distributions. the most reliable determinants of bank profitability are real gdp growth and the nonperforming loan (npl) ratio. the estimated conditional distributions reveal that, while higher growth would raise profits on average, a large swath of banks would most likely continue to struggle even amid a strong economic recovery. therefore, for some banks, a de ... | 2020 | 32895600 |
occupations and inequalities in the 21st century: what's in your wallet? | the study of occupations as a locus for social stratification research has a long and distinguished history in sociology. the authors in this issue present different perspectives on the current and future role of occupations as a foundation for inequalities research. this introduction provides a context for understanding how and why occupations became a focus of inequalities research, especially in the post-world war ii english-speaking world. i then discuss some of the economic changes that hav ... | 2020 | 32895591 |
minimum retesting intervals in practice: 10 years experience. | background minimum retesting intervals (mri) are a popular demand management solution for the identification and reduction of over-utilized tests. in 2011 association of clinical biochemistry and laboratory medicines (acb) published evidence-based recommendations for the use of mri. aim the aim of the paper was to review the use of mri over the period since the introduction of these recommendations in 2011 to 2020 and compare it to previous published data between 2000-2010. methods a multi-sourc ... | 2020 | 32892171 |
comparison of miniaturized percutaneous nephrolithotomy and retrograde intrarenal surgery: which is more effective for 10-20 mm renal stones in children? | to compare miniaturized percutaneous nephrolithotomy (mini-pnl) and retrograde intrarenal surgery (rirs) in children with 10-20 mm renal stones. materials and methods: between 2015 and 2019, 63 pediatric patients aged under 16 years who under went mini-pnl and rirs for the treatment of kidney stones sized 10-20 mm were analyzed retrospectively. the mini-pnl group (n=30) was defined as group 1 and the rirs group (n=33) was defined as group 2. peri-operative data including stone-free rate, operati ... | 2020 | 32886079 |
validation of a finite element model with six-year-old child anatomical characteristics as specified in euro ncap pedestrian human model certification (tb024). | accident statistics show that more than 80% of car-to-pedestrian collisions (cpc) occur when pedestrians cross the road. it is very important to establish a finite element model with natural walking posture to study the kinematics and injury mechanism of pedestrians. in this study, a finite element model of six-year-old child pedestrian is developed with detailed anatomical characteristics and posture parameters as specified in euro ncap pedestrian human model certification (tb024). the numerica ... | 2020 | 32875820 |
impact of extended release naltrexone on health-related quality of life in individuals with legal involvement and opioid use disorders. | understanding the impact of medications for opioid use disorder on health related quality of life (qol) may help to explain why few individuals with legal involvement remain in treatment, specifically those receiving opioid antagonists. qol is an established predictor of treatment retention and has been shown to improve with some treatment for opioid use disorder. yet limited research has examined qol with opioid antagonists. we examined the impact of extended release naltrexone (xr-ntx) on qol ... | 2020 | 32870122 |