Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [measurement of serum t3 and t4 by solid phase radioimmunoassay using latex particle (author's transl)]. | 1981 | 7277881 | |
| [measurement of free thyroxine in serum with immo phase free t4 ria kit (author's transl)]. | 1981 | 7277883 | |
| [solid phase radioimmunoassay of serum thyroxine and triiodothyronine -fundamental and clinical evaluation of amerlex t4 and t3 (author's transl)]. | 1981 | 7277884 | |
| [studies on free thyroxine measurement with radioimmunoassay kit -evaluation of gammacoat free t4 kit (author's transl)]. | 1981 | 7277885 | |
| [treatment of invasive epitheliomas involving the urinary tract or with extension to neighboring organs (urinary t3 and t4)]. | 1981 | 7280521 | |
| atrophic autoimmune thyroiditis: relationship between the clinical state and intrathyroidal iodine as measured in vivo in man. | the intrathyroidal iodine (iti) was measured by means of the x-ray fluorescence method in 58 patients suffering from atrophic autoimmune thyroiditis (aat). they were divided into 4 groups according to their basal t4, basal tsh, and the peak tsh response after trh administration. forty-eight normal subjects served as controls. a progressive fall of iti was found, with less iti in the first grade aat patients as compared to the controls. a negative correlation between basal tsh and iti could be sh ... | 1981 | 7263834 |
| human placenta is an active site of thyroxine and 3,3'5-triiodothyronine tyrosyl ring deiodination. | human placental homogenate deiodinates the tyrosyl ring of t4 and t3, converting these active thyroid hormones to the inactive iodothyronines, rt3 from t4, and 3,3'-diiodothyronine and 3'-monoiodothyronine from t3. the conversion of t4 or rt3 is time, temperature, ph, and protein content dependent and does not occur in the absence of the thiol-regenerating agent dithiothreitol. phenolic ring deiodination of t4, t3, and rt3 was not detected. failure of the transplacental passage of t4 and t3 from ... | 1981 | 7263836 |
| thyroid hormone levels after acute l-thyroxine loading in hypothyroidism. | while extrathyroidal conversion of t4 to t3 sustains circulating t3 blood levels in patients receiving maintenance doses of l-t4, the serum t3 rise after the acute administration of large doses of l-t4 may involve an additional mechanism, t3 contamination in l-t4 preparations. l-t4 (1000 micrograms; synthroid) was given orally to four noncompliant hypothyroid individuals (mean t4, 1.0 micrograms/dl; mean t3, 28 ng/dl). continuously withdrawn blood sampling revealed a mean rise in serum t4 to 7.7 ... | 1981 | 7263838 |
| urinary excretion of free and conjugated 3',5'-diiodothyronine and 3,3'-diiodothyronine. | rias for the estimation of 3',5'-diiodothyronine (3',5'-t2) and 3,3'-diiodothyronine (3,3'-t2) in human urine have been established. the urinary excretion of both glucuronide and sulfate conjugates of t2 and of t4, t3, and rt3 were estimated by means of enzymatic deconjugation. in healthy controls, the mean excretion (picomoles per 24 h) of free t4 was 1820, that of free t3 was 813, that of free rt3 was 77, that of free 3',5'-t2 was 13, and that of free 3,3'-t2 was 674. the total excretion of fr ... | 1981 | 7263841 |
| a new human photosensitive subject with a defect in the recovery of dna synthesis after ultraviolet-light irradiation. | a non-sensitive, 8-yr-old male patient (termed uv81ko) with only acute recurrent sunburns and without any other physical or neuromental retardations was studied. the patient's skin exhibited lowered minimal erythema doses between 280 and 300 nm monochromatic wavelengths without delayed peaking of erythema. uv81ko skin fibroblasts in culture was 5-fold more sensitive to 254 nm uv killing than normal cells, though the response of obligatory heterozygotes was normal. uv81ko cells were also more sen ... | 1981 | 7264357 |
| interactions of bacteriophage t4-coded gene 32 protein with nucleic acids. ii. specificity of binding to dna and rna. | 1981 | 7265197 | |
| interactions of bacteriophage t4-coded gene 32 protein with nucleic acids. i. characterization of the binding interactions. | 1981 | 7265204 | |
| hypothyroxinemia in critically ill patients as a predictor of high mortality. | thyroid function was measured in 86 patients hospitalized in an intensive care unit. two patients were found to have primary hypothyroidism and were excluded from the study. hypothyroxinemia with normal thyroid-stimulating hormone (tsh) levels was found in 22% of the patients and was associated with a high mortality (thyroxine [t4] levels less than 3.0 micrograms/dl, 84% mortality; t4 levels of 30 to 5.0 micrograms/dl, 50% mortality; and t4 levels greater than 5.0 micrograms/dl, 15% mortality). ... | 1981 | 7431627 |
| effects of intracoronary administration of bradykinin on the impulse activity of afferent sympathetic unmyelinated fibers with left ventricular endings in the cat. | in anesthetized and artificially ventilated cats, we recorded the impulse activity of 23 afferent sympathetic unmyelinated fibers with left ventricular endings, dissected from the left sympathetic rami t3 and t4. all fibers displayed a spontaneous discharge at a rate of 0.79 +/- 0.2 (mean +/- se) impulses/sec. during constriction of the thoracic aorta, the discharge increased to 1.92 +/- 0.2 impulses/sec. during myocardial ischemia, produced by interruption of left main coronary artery perfusion ... | 1981 | 7438347 |
| production and release of thyrotropin and its subunits by monolayer cultures containing bovine anterior pituitary cells. | we have developed a dispersed cell monolayer system derived from bovine anterior pituitary glands. fresh 1- to 6-week-old calf anterior pituitaries were mechanically and enzymatically dispersed and incubated with dulbecco's modified minimal essential medium containing 10% hypothyroid goat serum. the media and cell extracts from confluent monolayers were analyzed for bovine tsh and free alpha, and tsh beta subunits by specific homologous rias. basal levels of tsh, free alpha, and free tsh beta su ... | 1981 | 7449729 |
| effect of graded doses of thyrotropin on exocytosis and early phase of endocytosis in the rat thyroid. | our previous studies on the follicle cell have shown that exocytosis and endocytosis induced by a large dose of tsh (500 mu) are functionally related elements of a redistribution of membrane in the apical cell region. to explore the significance of exocytosis at submaximal levels of stimulation, t4-treated rats were injected iv with 5 or 50 mu tsh 5, 10, or 20 min before perfusion fixation of the thyroid. additional groups were given 20 or 100 mu tsh or saline 20 min before fixation. electron mi ... | 1981 | 7449731 |
| the influence of fasting and the thyroid state on the activity of thyroxine 5'-monodeiodinase in rat liver: a kinetic analysis of microsomal formation of triiodothyronine from thyroxine. | in the present studies, we have evaluated the effects of fasting, variations in thyroid state, and interactions thereof on the kinetic properties of the microsomal enzyme in rat liver that generates t3 from t4. the formation of t3 and t4 (t3-neogenesis) in preparations of rat liver microsomes enriched with 10 mm dithiothreitol was monitored by assessing the formation of [125i]t3 from [125i]t4 in the presence of various concentrations of stable t4. t3-neogenesis in this system was a saturable pro ... | 1981 | 7449736 |
| interaction of methemoglobin with inositol hexaphosphate. presence of the t state in human adult methemoglobin in the low spin state. | the interaction of human methemoglobin with inositol hexaphosphate (ihp) was examined by proton nmr spectroscopy. upon addition of ihp, new proton peaks which are distinguishable from those observed in the absence of ihp appeared irrespective of the spin state of the ferric heme iron. the ihp-induced nmr peaks of low spin azide methemoglobin were not observed when azide was titrated to stripped aquomethemoglobin. therefore, it was indicated that the ihp-induced peaks are not due to the slight di ... | 1981 | 7451474 |
| hemiaplasia of the thyroid with thyrotoxicosis. | four patients with hemiaplasia of the thyroid gland presented with thyrotoxicosis. each patient was noted to have unilateral goiter without palpable thyroid tissue on the contralateral side. investigation of these patients included measurements of serum l-t4, t3, thyroglobulin, thyroid microsomal antibody, long acting thyroid stimulator (lats), and long acting thyroid stimulator protector (lats-p). in addition, an 131i thyroid scan was performed on each patient and was repeated after tsh adminis ... | 1981 | 7451642 |
| falsely elevated serum thyrotropin (tsh) in newborn infants: transfer from mothers to infants of a factor interfering in the tsh radioimmunoassay. | in a tsh screening program for congenital hypothyroidism we detected seven newborn infants with normal plasma t4 and t3 levels but high immunoassayable tsh. similar findings were obtained in their mothers. serial plasma dilution curves, with and without the addition of normal rabbit serum to the samples, showed that the result of tsh assay performed with antihuman tsh rabbit antiserum was falsely elevated in mothers and infants by an interfering factor. follow-up of the infants demonstrated that ... | 1981 | 7451644 |
| relationship between hepatic malate dehydrogenase and thyroid hormones in the chicken during embryogenesis and the neonatal period. | the synthesis of hepatic cytosol malate dehydrogenase (mdh) can be stimulated by thyroid hormones under various conditions, and consequently, this enzyme has been considered as a marker of the expression of thyroid hormone action. since the concentrations of serum thyroid hormones increase considerably during the late phase of chick embryogenesis, we have studied the relationship between this phenomenon and liver mdh activity. a delay of 5 days was observed between the increase in circulating t4 ... | 1981 | 7460821 |
| alterations of serum thyroxine, triiodothyronine, and thyrotropin in the progeny of hypothyroid rats. | thyroid function in the progeny of hypothyroid rats was studied from 19 days of gestation until adulthood. total t4, t3, and tsh were measured by ria in the sera of control, surgically thyroidectomized (tx), and gh-treated tx pregnant rats and their progeny from the late fetal period through adulthood. by the 22nd day of gestation, the fetuses of tx mothers had t4 and tsh levels significantly above those of their controls. this condition, whereby fetal serum t4 and tsh levels were elevated, was ... | 1981 | 7460831 |
| homologous radioimmunoassay for canine thyrotropin: response of normal and x-irradiated dogs to propylthiouracil. | a ria for canine tsh (ctsh) has been developed using a double antibody method. rabbit anti-ctsh antisera was slightly cross-reactive with ovine tsh. no evidence of cross-reactivity was noted with human, bovine, rat rsh, or ovine lh. serum ctsh in euthyroid dogs (9-10 yr of age; 7-14 kg) was 7.0 +/- 0.9 ng/ml (mean +/- se; range, 2.7-7.9). normal and x-irradiated (localized to the thyroid or cranium) dogs received 334 mg propylthiouracil (ptu) im in oil daily for 1 week as a goitrogenic challenge ... | 1981 | 7460852 |
| congenital goiter and the development of metastatic follicular carcinoma with evidence for a leak of nonhormonal iodide: clinical, pathological, kinetic, and biochemical studies and a review of the literature. | we report a large kindred of patients with congenital goiter, followed for 15 yr, in which two siblings (one male and one female) developed metastatic follicular thyroid carcinoma. these two patients were evaluated by iodine kinetic analysis. none of the classical defects of t4 biosynthesis was present in either patient. rather, both patients had extremely rapid rates of iodine turnover, with elevated 131i uptake and excessive spillage of iodide in the urine. serum iodoalbumin was present, proba ... | 1981 | 7462393 |
| serum thyroglobulin levels in the newborn. | to study the pattern of thyroglobulin (tg) serum concentrations in the first days of life, tg, tsh, t3, and t4, were measured in both maternal and cord blood at delivery and 1, 6, 12, 24, 48, 72, and 96 h after birth in 16 newborns. tg levels at birth wee higher in cord blood than in maternal blood. after birth, a prolonged tg rise occurred. the increased levels became significant at 6 h and were maintained throughout the study. tg levels were not correlated with serum levels of t3, t4, and tsh. ... | 1981 | 7462396 |
| age-related changes of serum 3,3'-diiodothyronine, 3',5'-diiodothyronine, and 3,5-diiodothyronine concentrations in man. | to evaluate the effects of aging on t4 metabolism, serum 3,3'diiodothyronine (3,3'-t2), 3',5'-diiodothyronine (3',5'-t2), and 3,5-diiodothyronine (3,5-t2) as well as t4, t3, and rt3 concentrations were determined by rias in 81 normal subjects, aged 24-81 yr. 3,3'-t2, 3',5'-t2, and 3,5-t2 antisera were prepared by immunizing rabbits with the protein conjugate of each diiodothyronine. since the 3',5'-t2 antiserum cross-reacted with rt3 to the extent of 1.8%, correction was made by subtracting 1.8% ... | 1981 | 7462404 |
| [effect of the length of egg storage on duration of incubation and serum thyroid hormone levels in the chick embryo]. | after storage at 12 degrees c and 90 to 95 p. 100 humidity, for periods of 1, 5, 8, 11 and 14 days, rhode island red eggs were incubated at 37.5 degrees c and 60 p. 100 humidity. whatever the total duration of incubation within the experimental conditions, maximal serum levels of triiodothyronine (t3) and thyroxine (t4) were obtained the day of pipping. embryos having perforated the air-space membrane the day before pipping showed elevated serum t3, but not t4, levels as compared to embryos with ... | 1981 | 7349543 |
| elevation of serum 3,5,3'-triiodothyronine and thyroxine levels in rats fed remington diets; opposing effects of nutritional deficiency and iodine deficiency. | in the course of experiments on iodine deficiency induced by remington diets in rats, we observed that the remington diet supplied by icn nutritional laboratories, though very deficient in iodine (less than 20 micrograms i/kg), did not lead to the rapid loss of thyroid iodine and the rapid decrease in serum t4 expected on the basis of previous studies with a similarly iodine-deficient remington diet from another source. in searching for an explanation for this observation, we noted that the icn ... | 1981 | 7472266 |
| thyroid function in lactating women using the progestasert system. | this study determines the thyroid hormone levels, in serum and milk, of 46 healthy lactating women fitted with the progestasert system immediately postpartum. the ages of the women ranged from 28 to 35 years, parity from 3 to 6. they were divided into 2 groups: 1) menstruating and lactating women, and 2) amenorrheic and lactating mothers. the 1st group was subdivided into: 1) non-iud users (n=11); 2) cu t 200 users (n=9); and 3) progestasert users (n=6). the 2nd group was subdivided into: 1) ... | 1981 | 12336866 |
| effects of diet, exercise and anorexigenic drugs on serum thyroid hormones. | the serum levels of t4, t3 and rt3 were estimated in moderately obese women treated with diet (900-1000 kcal) and 4 h of exercise, supplemented with placebo or anorexigenic drugs (phenmetrazine, phentermine and mazindol). after 12 days of treatment, no change in serum t4 occurred in the placebo group (-4%), while in the groups with anorexigenic drugs a significant rise of t4 was observed (phenmetrazine +33%, phentermine +14% and mazindol +20%). serum t3 decreased significantly in the placebo and ... | 1980 | 7472292 |
| sequential deiodination of thyroxine to 3,3'-diiodothyronine via 3,5,3'-triiodothyronine and 3,3',5'-triiodothyronine in rat liver homogenate. the effects of fasting versus glucose feeding. | the characteristics of thyroxine (t4) deiodination to 3,5,3'-triiodothyronine (t3) and 3,3',5'-triiodothyronine (rt3) and of each of the latter to 3,3'-diiodothyronine (3,3't2) were examined in rat liver homogenate. each of the four reactions was enzymatic in nature, demonstrating ph and temperature optima, and tissue and time dependence. all reactions were considerably augmented (greater than 10-fold) by the presence of a thiol agent. at ph 7.2 with 2 mum t4 as substrate, rt3 generation was 3.3 ... | 1980 | 7350162 |
| thyroid function following neck irradiation for malignant lymphoma. | thyroid function tests for t3 resin (t3-r), serum thyroxine (t4) and serum thyroid stimulating hormone (tsh) were measured in 70 consecutive patients who had previously undergone lymphangiography and neck irradiation for malignant lymphoma. all were in remission and clinically euthyroid. the abnormalities found were: 23 (33%) patients hypothyroid by tsh, 14 (20%) with subnormal t4, and 21 (30%) with subnormal t3-r values. none of the patients were biochemically hyperthyroid. the prevalence and m ... | 1980 | 7350607 |
| elevated serum concentrations of triiodothyronine in hypothyroid patients. values for patients receiving usp thyroid. | serum concentrations of thyroxine (t4), triiodothyronine (t3), and thyroid-stimulating hormone (tsh) were measured for 14 hypothyroid patients while they were receiving usp desiccated thyroid and after six weeks of therapy with comparable doses of levothyroxine sodium (na-l-thyroxine). therapy with usp thyroid caused supraphysiologic elevations in the concentration of t3 in 13 patients. treatment with levothyroxine resulted in serum concentrations of t3 that were within the range of normal. we b ... | 1980 | 7350782 |
| neoglottic reconstruction after total laryngectomy. staffieri's techniques: a report of 18 cases. | mario staffieri and associates developed a technique for reconstruction of a phonatory neoglottis in 1970. since then staffiere has performed over 100 of these procedures with approximately a 90% success rate. the technique has been used in 18 cases at the university of texas medical branch in galveston with certain variations. all patients received a wide field total laryngectomy for t3 or t4 endolaryngeal or pyriform sinus carcinomas. of these 18 patients, two did not have neoglotic fistulas c ... | 1980 | 7352911 |
| fluorescence study of the association between gene 32 protein of bacteriophage t4 and poly(1-n6-ethenoadenylic acid). evidence for energy transfer. | we have studied the association of gene 32 protein of bacteriophage t4 with a fluorescent polynucleotide: poly(1-n6-ethenoadenylic acid). the presence of a bridge between the n(1) nitrogen atom and the c(6) amino group of adenine bases did not alter the affinity of the protein for the polynucleotide as compared to poly(ra) and heat-denatured dna. this suggests that this region of the nucleic acid bases is not required in protein 32-polynucleotide complexes. the formation of gene 32 protein-poly( ... | 1980 | 7353019 |
| retinal projections in the australian lungfish. | autoradiographic analysis of the primary retinofugal projections in the australian lungfish reveals contralateral retinal projections to a ventral portion of the periventricular preoptic nucleus, throughout its rostrocaudal extent, and to 4 distinct terminal fields in the thalamus. only one of these thalamic fields (t4) likely receives dendrites solely from dorsal thalamic neurons. thalamic terminal field 1 probably receives dendrites from both dorsal and ventral thalamic neurons, and fields 2 a ... | 1980 | 7353182 |
| transient hypothyroidism after iodine-131 treatment of thyrotoxicosis. | thirty consecutive patients with thyrotoxicosis were followed up at monthly intervals for 6 months after treatment with iodine-131. serum total t4, serum total t3, and serum tsh response to trh were measured at each review. biochemical evidence of hypothyroidism (low t4 raised basal tsh) developed in 18 patients 1-4 months after treatment. in 5 of these patients, symptoms and signs of hypothyroidism remained absent or minimal and spontaneous recovery of thyroid function occurred during the ensui ... | 1980 | 7354108 |
| effects of dietary phenylalanine and tyrosine on circulating thyroid hormone levels and growth in the chick. | studies were conducted to investigate the effects of a phenylalanine-tyrosine deficiency on serum thyroid hormone concentrations and growth in chicks from 0 to 14 days of age. birds fed diets severely deficient in aromatic amino acids (aaa), lysine or valine were found in most trials to have reduced serum concentrations of either 3,5,3'-triiodothyronine (t3) or 3,5,3',5'-tetraiodothyronine (t4). approximately one-half of the samples assayed did not show detectable levels of 3,3',5'-triiodothyron ... | 1980 | 7354377 |
| [thyrotoxicosis with low t3 and high reverse t3 levels. 9 cases (author's transl)]. | in common forms of hyperthyroidism serum levels of triiodothyronin (t3) are higher than those of thyroxin (t4) and isolated elevations of serum t3 have even been noted. we report 9 cases of proven hyperthyroidism with normal or low levels of t3 and elevated t4 and reverse t3 (rt3). most out of the patients were more than seventy years old and had associated diseases. our data show that the low t3 with elevated rt3 syndrome--which has been noted in many metabolic and pathologic conditions--can co ... | 1980 | 7355063 |
| concentration of coliphages from large volumes of water and wastewater. | membrane filter adsorption-elution technology has been extensively used for the concentration and detection of animal viruses from large volumes of water. this study describes the development of positively charged microporous filters (zeta plus) for the concentration of coliphages from large volumes of water and wastewater. four different coliphages were studied: ms-2, phi x174, t2, and t4. positively charged microporous filters were found to efficiently adsorb these coliphages from tap water, s ... | 1980 | 7356323 |
| transcription of a specific product from cloned t4 trna genes in xenopus germinal vesicle extract. | 1980 | 7356474 | |
| purification and properties of a dna ligase from a soluble dna replication complex. | a dna ligase has been purified from a subnuclear soluble replication complex isolated from adenovirus type 2-infected human kb cells. dna ligase activity could not be demonstrated using an exogenous template until the complex was dissociated, suggesting that the ligase activity may be a component of the complex. the purified enzyme was free of endonuclease, exonuclease, 5'-nucleotidase, and phosphatase activities, and had a molecular weight of 105 000, as estimated by sedimentation in a glycerol ... | 1980 | 7357002 |
| radioimmunoassay for mouse nerve growth factor (ngf). effects of thyroxine administration on tissue ngf levels. | a sensitive and specific radioimmunoassay (ria) has been developed for beta-nerve growth factor (ngf) purified from the submaxillary gland of the adult male mouse. the ria is sensitive to 13 pg/assay tube with an intra-assay coefficient of variation of 7% and an interassay coefficient of variation of 11.8%. of the substances tested for immunological cross-reactivity in the ria, only mouse epidermal growth factor caused significant displacement of the radiolabeled ligand; 11% at a dose of 10 micr ... | 1980 | 7357457 |
| serum levels of thyroid hormones in liver diseases. | concentrations of thyroid hormones and thyrotropin (tsh) were measured in sera of clinically euthyroid patients with various liver diseases and compared with normal controls. the mean serum concentration of 3,3',5'-triiodothyronine (reverse t3, rt3) was significantly increased in patients with decompensated liver cirrhosis (p less than 0.01). this increase seemed to be dependent upon the hepatic damage, although it was not significant in patients with acute hepatitis, chronic hepatitis and compe ... | 1980 | 7357737 |
| new androgen-stimulated proteins in the kidneys of female mice. | testosterone administration to female mice for 25 days produced a 70% increase in total kidney protein in both a/j and c57bl/6j mice. this is in contrast to the known androgen-responsive proteins, such as beta-glucuronidase and alcohol dehydrogenase, which each represent less than 1% of the total kidney proteins even after maximum stimulation. to investigate this discrepancy, we initiated a study to identify major proteins which increase with androgen treatment. three new cytoplasmic proteins de ... | 1980 | 7358032 |
| hyperthyroidism in the cat: ten cases. | in ten neutered crossbred cats 10 to 14 years old and of both sexes, hyperthyroidism was evidenced by hyperactivity, weight loss despite increased appetite, frequent defecation with bulky stools, thirst, polyuria, moderately elevated temperature, increased heart rate and size, sometimes with murmurs and arrhythmias, and palpable enlargement of one or both thyroid lobes. the diagnosis of hyperthyroidism was confirmed on the basis of high serum concentrations of thyroxine (t4) and triiodothyronine ... | 1980 | 7358553 |
| lack of influence of thyroid antibodies on thyroid function in the newborn infant and on a mass screening program for congenital hypothyroidism. | data regarding the incidence and effect of maternal thyroid antibodies on neonatal thyroid function are conflicting. in order to elucidate this aspect, antimicrosomal thyroid antibodies were measured: (1) in cord serum of a normal populations, (2) in the eluate of blood spots of infants with normal filter paper spot t4 and tsh, (3) in the eluate of blood spots from our recalled population (low t4 and normal tsh), and (4) in serum of detected hypothyroid infants. the incidence of mca with titer g ... | 1980 | 7359229 |
| changes in thyroid function tests during danazol therapy. | danazol is a synthetic steroid with antigonadotropic properties useful in treating endometriosis, especially in young infertile women. prior to its availability for clinical use in september 1976, thyroid function studies other than thyroid-stimulating hormone (tsh), which was normal, had not been reported. soon after danazol began to be used in the infertility clinic to treat documented endometriosis, it was observed that changes occurred in thyroid function studies. while no patients manifeste ... | 1980 | 7360440 |
| [prevention of lymphogenic metastasis in the surgical treatment of rectal cancer]. | it was shown that during radical operations, performed for local spread of rectal cancer (t3--t4, p3--p4), in most patients tumor cells identical to the primary tumor are found in the thoracic duct lymph. to the end of prophylaxis of intraoperative lymphogenic dissemination of tumor cells 71 patients with rectal cancer, spread locally, were subjected preoperatively to endolymphatic infusion of 10% dibunol solution in iodolipol or chromolymphotrast. the preparation was found to be completely depo ... | 1980 | 7361491 |
| electrophysiologic studies of cutaneous nerves of the thoracic limb of the dog. | the cutaneous innervation of the thoracic limb was investigated in 36 barbiturate-anesthetized dogs, using electrophysiologic techniques. the cutaneous area (ca) innervated by each cutaneous nerve was delineated in at least five dogs by stroking the hair in the area with a small watercolor brush while recording from the nerve. mapping of adjacent ca revealed areas of considerable overlapping. the part of the ca of a given nerve supplied by only that nerve is referred to as its autonomous zone. o ... | 1980 | 7362125 |
| transient elevation of serum thyroid hormone concentration after initiation of replacement therapy in myxedema. | measurements of thyroid hormone concentrations in serum are commonly used to determine the proper dose of hormone replacement. we have noted that early in the course of thyroxine (t4) replacement in myxedema, serum t4 concentrations may be transiently elevated before reaching a lower "steady-state" level. this observation is illustrated in a study of six patients. serum t4, free thyroxine index, and triiodothyronine (t3) rose to peak concentrations at 2 to 6 weeks, 35% to 120% above the values a ... | 1980 | 7362153 |
| plasma norepinephrine, epinephrine, and thyroid hormone interactions in severely burned patients. | in this prospective study of thyroid catecholamine interactions, 15 severely burned patients were divided into two groups. nine patients receiving 200 micrograms/day of triiodothyronine constituted the t3-treated group. eight additional patients constituted the untreated group. mean serum concentrations of t3 were significantly lower in the untreated group than in the treated group. mean serum thyroxine (t4) concentrations were significantly higher in the untreated group than in the treated grou ... | 1980 | 7362451 |
| thyroid hormone relationships in the fetal and newborn lamb. | plasma thyroxine (t4) and reverse triiodothyronine (rt3) concentrations have been measured in chronically catheterised sheep fetuses during the last third of gestation. in some animals t4 and rt3 concentrations fell before delivery but there was no change in the t4/rt3 ratio. in several serially sampled fetuses a small rise in plasma triiodothyronine concentration has been demonstrated in the days preceding delivery. infusion of cortisol to fetuses commencing at 130 days of gestation (term 147 d ... | 1980 | 7362852 |
| divergent changes of thyroxine-5'-monodeiodination in rat pituitary and liver during maturation. | t4-5'-monodeiodination in pituitary fragments and liver homogenates, serum thyroid hormones, an index of serum thyroid hormone protein binding, and serum tsh were measured in rats aged 2-72 days. serum t4, t3, and tsh concentrations were lower in the 2-, 4-, and 9-day-old rats than in adult rats. the serum thyroid hormone-binding index was highest in neonatal rats, fell to a nadir at 21 days, and rose thereafter. the intrapituitary t4-5'-monodeiodination rate was 3.5 times the 72-day value in 2- ... | 1980 | 7363857 |
| effects of starvation on in vivo gluconeogenesis in hypo- and hyperthyroid rats. | studies were performed on rats in vivo to determine whether starvation disrupts glucose metabolic balance after removal of the thyroid gland. intact controls and thyroidectomized rats were injected daily with 0, 0.1, 1.8, or 25 microgram l-t4/100 g bw. glucose spaces were similar in all groups. the disappearance of labeled glucose from blood was faster in the thyroidectomized rats injected with 25 microgram l-t4 than in the other groups. starvation enhanced the production of [14c]glucose from [3 ... | 1980 | 7363866 |
| the nondeiodinative pathways of thyroxine metabolism: 3,5,3',5-tetraiodothyroacetic acid turnover in normal and fasting human subjects. | complete turnover studies of t4, t3, rt3, and 3,5,3',5-tetriodothyroacetic acid (ta4) were carried out in normal subjects given t4 (0.2 mg, by mouth daily) by the integration method. when compared to the five fed controls, the four fasting subjects showed a decrease of mean t3 disposal from 41 to 18 micrograms/day, an increase of mean rt3 disposal from 49 to 61 micrograms/day. the mean serum ta4 concentration rose from 53 to 112 ng/dl, while the ta4 metabolic clearance remained unchanged. the fr ... | 1980 | 7364927 |
| inhibition of hepatic binding of thyroxine by cholecystographic agents. | subsequent to studies indicating that cholecystographic agents and sulfobromophthalein (bsp) inhibit uptake of thyroxine (t(4)) by rat liver slices, the effect of such compounds on hepatic storage of t(4) in man has been examined. after intravenous administration of [(125)i]t(4) to five normal subjects, hepatic radioactivity, estimated by external gamma counting, rose to a peak in approximately 4 h and then declined in parallel with serum radioactivity. when a 6-g dose of the cholecystographic a ... | 1980 | 7364937 |
| interaction of thyroid hormone and hemoglobin. i. nature of the interaction and effect of hemoglobin on thyroid hormone radioimmunoassay. | gel filtration of human rbc lysate incubated with labeled t4 or t3 revealed co-elution of a major iodothyronine-binding fraction (r-2) and hemoglobin. solutions of purified human hemoglobin and t3 also showed co-elution of hormone and hemoglobin. because hematin and protoporphyrin were shown to bind labeled t3, the oxygen-binding site on hemoglobin was excluded as the site of iodothyronine-hemoglobin interaction. analysis of hormone binding by heme and globin moieties showed t3 binding to be lim ... | 1980 | 7365316 |
| measurement method for radioactive thyroxine, triiodothyronine, iodide, and iodoprotein in samples with low activity. | a method is described that incorporates resin extraction and thin layer chromatography to isolate and separate radioiodinated thyroxine (t4), triiodothyronine (t3), iodoprotein, and iodide in samples of human plasma up to 3 ml. tracer studies using this method showed that reverse t3 and 3',5' diiodothyronine (t2), as well as t4, were detected in the "t4 fraction," and that 3-3' t2 and 3' monoiodothyronine, as well as t3, were detected in the "t3 fraction." monoiodotyrosine and diiodotyrosine (di ... | 1980 | 7365515 |
| high-molecular-weight dna and the sedimentation coefficient: a new perspective based on dna from t7 bacteriophage and two novel forms of t4 bacteriophage. | the dna molecules from t7 bacteriophage and a recently obtained mutant form of t4d were studied. the dna of this t4 mutant contains cytosine in place of all of the glucosylated hydroxymethylcytosines normally present in t4. molecular weights were measured with an electron microscope technique, and sedimentation coefficients were determined in isokinetic sucrose gradients. t7 dna was found to have an mr of 26.5 x 10(6). the t4 mutant, which we have termed t4c, produces two distinct phage head and ... | 1980 | 7365870 |
| lack of protective effect of breast-feeding in congenital hypothyroidism: report of 12 cases. | hypothyroid babies being breast-fed (12 cases) or bottle-fed (33 cases) have been compared. anthropometric measurements at referral as well as biochemical values including plasma t4, t3, and thyroid-stimulating hormone were not significantly different. bone maturation expressed as number of ossification centers or their surface were identical. babies from both groups had similar psychologic performance at their first anniversay. it is concluded that breast-feeding does not protect against the de ... | 1980 | 7367075 |
| serum levels of thyrotropin, thyroxine, 3,3',5-triiodothyronine and 3,3',5'-triiodothyronine (reverse t3) in the first six days of life. | serum concentrations of thyrotropin (tsh), thyroxine (t4), 3,3',5-triiodothyronine (t3), and 3,3',5'-triiodothyronine (rt3) were determined in blood samples from 140 full-term healthy newborns, 110 appropriate weight and 30 large-for-gestational age, aged 1 to 6 days, delivered vaginally and breast-fed. serum tsh levels decreased progressively from the 1st to the 4th day; serum t4 levels increased, with a peak on the 2nd day, and then progressively decreased until the 6th day; serum t3 levels in ... | 1980 | 7368910 |
| chronic hemofiltration treatment. | fourteen patients (six males and eight females) have been treated with chronic hemofiltration three times weekly for three to 27 months with the post-dilution technique. all patients had previously been on regular dialysis treatment. patients were selected for hemofiltration because of dialysis-resistent hypertension (eight), symptoms of dialysis discomfort (five), hypertriglyceridemia (five) and polyneuropathy (seven). hypertension improved in six of eight patients, symptoms of dialysis discomf ... | 1980 | 7369895 |
| immunocompetence, immunosuppression, and human breast cancer. ii. further evidence of initial immune impairment by integrated assessment effect of nodal involvement (n) and of primary tumor size (t). | comprehensive immune function by integrated score was assessed in 158 operable, 55 inoperable, and 52 metastatic breast cancer patients relative to 107 healthy controls. the score was derived from in vivo response to ppd and dncb and in vitro lymphocyte stimulation by ppd and pha. proportion of e-rfc was significantly lower in patients than in controls but was not found to correlate directly with the above functional criteria. fifty-one percent of the patients with early, operable tumors were sh ... | 1980 | 7370952 |
| studies of the goitrogenic and tumorigenic effect of two goitrogens in combination with hypophysectomy or thyroid hormone treatment. | the influence of hypophysectomy, triiodothyronine (t3), and thyroxine (t4) on the goitrogenic and tumorigenic activity of methylthiouracil (mtu) and 1-methyl-2-mercapto imidazol (mmi) was studied in rats. hypophysectomy effectively prevented the development of thyroid hyperplasia and adenomas in mtu-treated animals. t3 reduced or abolished the weight loss of goitrogen-treated animals, and prevented the development of thyroid hyperplasia, adenomas, and pulmonary metastatic nodules. the effect of ... | 1980 | 7370956 |
| metabolic studies in mitral valve prolapse syndrome. a neuroendocrine--cardiovascular process. | symptomatic patients with mitral valve prolapse (mvp) frequently mimic thyrotoxicosis, hyperadrenergic states or hypoglycemia. twenty symptomatic patients with auscultatory and echocardiographic mvp were studied in the clinical research unit. t3, t4 and plasma cortisol were normal. patients with mvp had normal responses to oral glucose administration but higher glucose levels than the controls (p less than 0.05). twenty-four-hour urinary epinephrine (e) and norepinephrine (ne) were greater than ... | 1980 | 7371133 |
| [fundamental and clinical evaluation of phadebas t4 ria (author's transl)]. | 1980 | 7371205 | |
| [the basic and clinical evaluation of serum triiodothyronine uptake and thyroxin with spac t3 uptake kit and spac t4 ria kit (author's transl)]. | 1980 | 7371209 | |
| evidence against a major role of l-thyroxine at the pituitary level: studies in rats treated with iopanoic acid (telepaque). | to determine whether t4 has an intrinsic effect at the pituitary level, it would be important to block conversion of t4 to t3 completely. we have attempted to achieve this with iopanoic acid (iop), a radiographic contrast agent. we have then measured in the same animals the effects of such treatment on the conversion of t4 to t3 or on the deiodination of t3 and on the pituitary response to a dose of t4 or t3. plasma tsh levels and pituitary gh content were measured as biological end points. thyr ... | 1980 | 7371594 |
| hormone responsiveness of a transplantable rat chondrosarcoma. ii. evidence for in vivo hormone dependence. | we have previously demonstrated that the swarm rat chondrosarcoma responds to gh-dependent serum factors in vitro by increasing amino acid transport and macromolecular synthesis. the question of in vivo hormone dependence was evaluated by studying the growth of the tumor in hypophysectomized rats. tumor-bearing hypophysectomized rats were treated with saline, t4, cortisone, bovine gh (bgh), or combinations of these hormones. tumor growth was assessed in terms of tumor weight. histological appear ... | 1980 | 7371597 |
| [thyroxine and triiodothyronine blood plasma concentrations in sows and newborn pigs]. | plasma thyroxine (t4) and triiodothyronine (t3) concentrations of 11 sows and their 56 fetuses have been measured by radioimmunoassay between 80--112 days of intrauterine development. similar measurements were carried out in 20 piglets of 2 litters up to 24 hours of age and in sows; the latter within a period of 3 days before and 3 days after parturition. the average t3 concentration in the fetus was 0.30--0.41 ng/ml, that of t4 showed great variations between the litters. after 106 and 112 days ... | 1980 | 7371603 |
| circulating iodothyronines in juvenile diabetic outpatients. | serum t3, rt3, t4 and tsh were measured in ten healthy subjects, in nine juvenile diabetic outpatients in fair metabolic control (fasting plasma glucose 6.5 mmol/1, 2.6-9.5 mmol/1 (mean, range), hba1 10.1%, 8.1-12.2%), and in ten juvenile diabetic outpatients in poor metabolic control but without ketonuria (fasting blood glucose 15.1 mmol/l, 11.1-22.4 mmol/l, hba1, 13,8% 10.8-16,2%. serum t3 was identical in normal subjects and in diabetics in fair metabolic control. diabetics in poor metabolic ... | 1980 | 7371897 |
| melatonin and the thyroid. | chronic melatonin administration (100 microgram daily for 21 days) to male weanling rats increased basal tsh without altering peripheral hormone levels. there was an increase in radioactive thyroidal iodine uptake in the melatonin treated animals. melatonin increased the thyroid gland size relative to body weight and increased the total t4 content and t4:t3 ratio in the thyroid gland. there was no effect of melatonin on tsh response to trh or hypothalamic trh content. optic nerve section increas ... | 1980 | 7372268 |
| sulfhydryl group modulation and triiodothyronine generation in the human polymorphonuclear leukocyte. | the induction of phagocytosis in the human polymorphonuclear leukocyte and the attendant decrease in endogenous sulfhydryl group content were accompanied by a depression of the generation by the 27,000 x g particulate fraction of l-t3 and l-rt3 from substrate l-t4. a direct correlation between endogenous sulfhydryl group content and l-t3-generating activity was found to exist. the inhibitory influence of phagocytosis was prevented when phagocytosis was induced in the presence of a sulfhydryl gro ... | 1980 | 7372782 |
| hyperthyroidism due to excess thyrotropin secretion: follow-up studies. | follow-up studies of a woman with hyperthyroidism due to excessive tsh secretion, previously reported (1), are described. for most of the ensuing years, she has been treated with methimazole. on several occasions, methimazole was discontinued; each time elevations of serum tsh, t4, and t3 concentrations, similar in magnitude to those originally present, occurred. initially, her serum tsh concentrations fell substantially after dexamethasone administration and did not change after trh. the same r ... | 1980 | 7372792 |
| subcellular localization of thyroxine-5-deiodinase in rat liver. | l-thyroxine (t4) is monodeiodinated to 3,3',5'-triiodothyronine (rt3) and 3,3',5'-triiodothyronine (t3). a recent work has demonstrated that t4-5'-deiodinase is localized solely in the microsomes of rat liver, as was originally suggested. in this study identical subcellular localization was also found for t4-5-deiodinase. this is in contrast with a previous report, indicating that t4-5-deiodinase is present in the soluble cytosol fraction of rat liver. our results strongly indicate that the thyr ... | 1980 | 7373011 |
| low t4 and low ft4i in seriously ill patients: concise communication. | of 128 euthyroid hospitalized patients with nonthyroidal illnesses (nti), 33% had a low total thyroxine (t4). forty-three percent of the latter patients had a low free thyroxine index. in euthyroid patients with nti, free t4 was, with rare exceptions, within the range for well euthyroid controls. the free t4, as determined by two different radioimmunoassays, was diagnostically low in 34 of 37 hypothyroid patients without nti. however, in hypothyroid patients with nti, the free t4 determination w ... | 1980 | 7373413 |
| [reciprocal changes of triiodothyronine and reverse triiodothyronine in the early stage of myocardial infarction (author's transl)]. | the changes of thyroid hormones and tsh in plasma of males in the early stage of myocardial infarction are described. already on admission t3 was diminished and went on falling. on admission rt3 was elevated and reached its maximum after 19 hours. t4 and tsh did not show essential alterations. the results suggest that in the early stage of myocardial infarction a rapid shift of the monodeiodination of t4 to rt3 occurs instead of t3 with a quick decrease of t3 and increase of rt3 in the blood. | 1980 | 7374095 |
| participation of bacteriophage t4 gene 41 in replication repair. | the location of the non-essential t4 mutant uvs79, with defective replication repair, is described. after crosses with double mutants dispersed over the early region of t4, a linkage was observed with the double mutant am41 : am42. for more accurate location, crosses were made with single mutants. uvs79 proved to be located between mutants amc23 and amn81 in gene 41, as shown by 3-point crosses. no genetic complementation with respect to multiplicity reactivation was found between amn81 and uvs7 ... | 1980 | 7374656 |
| effect of dietary thyroid hormone on growth and feed efficiency of broilers. | broiler chickens were fed corn-soybean meal diets supplemented with either 3,5,3'-triiodothyronine (t3) or thyroxine (t4) in five trials. body weight gain and feed efficiency are reported for four trials. chickens fed t3 at 1.00 ppm had poorer weight gain and feed efficiency than controls, but t4 at that same dosage did not adversely affect performance. serum t3, t4, and 3,3',5'-triiodothyronine (rt3) were assayed by radioimmunoassay. t3 or t4 at 1.00 ppm in the diet resulted in respective serum ... | 1980 | 7375436 |
| [mechanism of the effect of thyroid hormones on renal function]. | chronic experiments were conducted on 32 dogs; it was shown that thyroxin (t4) administered in a dose of 50 micrograms/kg into the renal artery through the implanted catheter produced a primary action on the tubular apparatus of the kidney inducing natriuresis from the first minutes in the experimental kidney. high t4 doses (200 micrograms/kg) activated renal hemodynamics as well. natriuretic effect of t4 was not eliminated by alpha- and beta-adrenoblocker. triiodthyronine (t3) manifested a dire ... | 1980 | 7375455 |
| [radioimmunoassay for serum thyroxine by the antibody-coated test tube method (spac-t4 kit) (author's transl)]. | 1980 | 7375676 | |
| the effects of iopodate on the serum iodothyronine pattern in normal subjects. | the ingestion by normal subjects of 3 g of sodium iopodate, which is widely used in routine oral cholecystography, resulted in significant decreases of serum total and free t3 to a nadir on day 4 which averaged 43% and 40%, respectively, below initial mean values. total and free rt3 increased markedly to a peak on day 3, 244% and 189%, respectively, above initial mean values. total and free t4 and free t4 index rose to a maximum on day 4, but these changes were not statistically significant. a m ... | 1980 | 7376789 |
| effects of propylthiouracil and relatively small doses of iodide on early phase treatment of hyperthyroidism. | in order to compare the acute effects of three methods of treatment in hyperthyroid patients with diffuse goitre, values of thyroxine (t4), triiodothyronine (t3) in serum, t3-resin uptake (t3-u), free thyroxine index (ft4i) and free triiodothyronine index (ft3i) were employed as thyroid function parameters. in iodide (i-) group given iodine (3 or 6 mg/day) as iodinated lecithine once daily, the parameters were reduced acutely within one week after the start of treatment, reaching a plateau durin ... | 1980 | 7376794 |
| thyroidal response to peroral tsh in suckling and weaned rats. | the biological activity of perorally administered bovine thyroid-stimulating hormone (btsh) was investigated in suckling (14-day-old) and weaned (30-day-old) rats. animals were treated with water or btsh given either by subcutaneous injection or by the oral route. both suckling and weaned animals responded to subcutaneous administration of btsh by an increase in serum thyroxine (t4) and triiodothyronine (t3) concentrations. bovine tsh administered orally to weaned animals had no effect on thyroi ... | 1980 | 7377340 |
| analysis of failures after definitive irradiation for epidermoid carcinoma of the nasopharynx. | from 1955 to 1976, 111 patients were treated with definitive radiotherapy for epidermoid carcinoma of the nasopharynx. there was a definite correlation between recurrence at the primary site and t-stage; 9.5% of t1-2 patients, 38.1% of t3 patients and 54.1% of t4 patients had local recurrences. similarly, failure in the neck correlated with n-stage, being negligible for n0 and n1 but 28.6% for n2 and 36.1% for n3. the incidence of distant metastases had no correlation with t-stage but correlated ... | 1980 | 7379006 |
| [fundamental studies of s-8537 (phadebas t4 ria) kit (author's transl)]. | 1980 | 7379327 | |
| value of the free triiodothyronine index in the diagnosis of hyperthyroidism. | normalized t4 (t4n), total t3, t3 resin sponge uptake (t3u) and the response of tsh to trh were determined in 264 patients sent for diagnosis of thyroid function. many of these patients were diagnostic problem cases. those with disease or medication known to invalidate the trh test, but not those with abnormal thyroid hormone binding capacity in serum, were excluded. a free t3 index (ft3 index) was calculated as the product of total t3 and t3u. the ft3 index tended to decline with increasing age ... | 1980 | 7379813 |
| capacity of old versus young male rats to release thyrotropin (tsh), thyroxine (t4) and triiodothyronine (t3) in response to different stimuli. | serum tsh, t4 and t3 were measured by radioimmunoassay (ria) in 20-24 month old and 6-8 month old long-evans male rats during basal conditions, and upon exposure to cold temperature (4 degrees c), injection of ovine tsh, thyroidectomy, and t4 or t3 treatment. basal serum tsh values in the old and young rats were similar, but serum t4 and t3 levels in the old rats were significantly lower than in the young rats. no differences were observed in tsh release between old and young rats in response to ... | 1980 | 7379832 |
| thyroid hormones and efficiency of energy utilization in mice selected for body weight. | plasma thyroid hormones and energetic efficiency were examined in selected lines of mice during the fifth, sixth and seventh weeks of age. mice from an unselected control line (c2) and from lines selected for large (h6) or small (l6) 6-week body weight were fed either ad libitum or restricted to approximately 75% of ad libitum intake. the h6 line was more efficient in energy deposition than the c2 and l6 lines with regression coefficients of change in body energy (kcal/kg0.75) on metabolizable e ... | 1980 | 7381593 |
| [solid phase radioimmunoassay for thyroxine--foundamental and clinical studies of corning t4 ria kit (author's transl)]. | 1980 | 7382173 | |
| [radioimmunoassay for free thyroxine in serum by gammacoat free t4 radioimmunoassay kit compared with equilibrium dialysis method (author's transl)]. | 1980 | 7382188 | |
| minimal placental transfer of l-thyroxine (t4) in the rat. | studies of l-thyroxine t4 kinetics and placental transfer were conducted in pregnant rats during the last days of gestation using radioiodine labeled and unlabeled t4. the maternal t4 secretion rate was 53.0 +/- 6.9 ng/hr/100 g body wt. the placental transfer rate was 0.463 +/- 0.196 x 10(-3)/hr at 18 days and 1.516 +/- 0.147 x 10(-3)/hr at 20 days. from these results, we calculated that at 20 days of gestation, 80 +/- 8 pg/hr were transfered to the fetus, less than 1% of the fetal production ra ... | 1980 | 7383742 |
| inhibition of uv and psoralen-plus-light mutagenesis in phage t4 by gene 43 antimutator polymerase alleles. | 1980 | 7384228 | |
| solitary osteochondroma of t4 with thoracic cord compression. | a patient with a solitary osteochondroma of t4 presented with a five-year history of back pain and progressive paraparesis. conventional and computed tomography delineated the tumor, which was totally removed via a thoracic laminectomy. osteochondroma is an unusual cause of spinal cord compression. | 1980 | 7385001 |
| [serum levels of thyroxine (t4), triiodothyronine (t3) and thyrotropic hormone (tsh) in chronic kidney insufficiency]. | the authors studied the serum level of t3, t4 and tth in 30 euthyroid patients with chronic renal insufficiency (cri), distributed in three groups of 10 patients. i group includes patients with cri ii and iii stage without dialysis treatment, patients with cri are included in the ii group, being under hemodialysis treatment from 5 to 12 months, and in iii group--patients dialized three and more years. low average values of t3--0.65 mg/ml were established only in the first group; in 8 patients, o ... | 1980 | 7385804 |
| t4 degradation rate and plasma levels of tsh and thyroid hormones in ten young bulls during feeding conditions and 48 h of starvation. | the effect of starvation on thyroid hormones was studied during a starvation period of 48 h in 10 young bulls. mean thyroxine degradation rate decreased from k/day 0.32 during feeding to 0.23 during fasting. mean plasma concentration of t4 decreased to 75% of normal, and it was calculated that the mean thyroxine secretion rate during the starvation period was 24% of normal. plasma concentration of free thyroxine decreased to 54% of normal, indicating that the concentration of binding protein was ... | 1980 | 7386113 |
| thyroid hormone levels related to energy and nitrogen balance during weight loss and regain in adult sheep. | caloric deprivation (feeding 50 and 25% of the original maintenance requirement for 126 days), followed by overnutrition (feeding 133 and 200% of the original maintenance requirement) for 37 days, were induced in 7 adult sheep. before and after the periods of undernutrition and after overnutrition the animals were fasted (total energy withdrawal) for 5 days. energy- and nitrogen-balances were determined and related to concentrations of thyroxine (total: t4; free: ft4), 3,5,3'-triiodothyronine (t ... | 1980 | 7386114 |
| t4, t3 and reverse t3 in the plasma of rats during the first 3 months of life. | a very sensitive radioimmunoassay for reverse t3 in rat plasma is described. the concentrations of t4, t3 and reverse t3 in plasma of male and female rats were determined during the first 3 months of life. t4 concentrations reached a maximum value of 5.2 +/- 0.7 microgram/100 ml (mean +/- sd) when the rats were about 16 days old. as of day 28 the average serum t4 was approximately 4 microgram/100 ml. concentrations of t3 reached a maximum value of 168 +/- 34 ng/100 ml (mean +/- sd) during the 16 ... | 1980 | 7386115 |
| eeg spectral analysis in schizophrenia. | four channels of eeg (t4-t6, p4-02, t3-t5, p3-01) were recorded from several groups of control subjects and schizophrenia patients on analogue tape. they were later digitized and analysed by computer; power spectra were computed for 30 second epochs of eeg per channel; eyes closed, eyes open. no difference between normal controls and neurotic in-patients was apparent. an acute schizophrenic group had less alpha power, this change being confined largely to the temporal areas. a chronic outpatient ... | 1980 | 7388249 |