Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| changes in the eu legislation on trichinella inspection--new challenges in the epidemiology. | the european union (eu) countries are searching for new ways to certify meat free of trichinella; however, with the expansion of the eu, the acceptance of a unilateral method is complicated by the variability of pig and human trichinellosis among eu countries, where significantly higher prevalence rates have been observed in the newly added eastern countries. several attempts have been made to define trichinella-free areas, but certification of trichinella-free pig production farms appears to be ... | 2005 | 16039781 |
| evaluation of surgical models for renal collecting system closure during laparoscopic partial nephrectomy. | to evaluate the utility of the porcine and canine models for collecting system closure after partial nephrectomy involving violation of the renal collecting system. advanced surgical technologies and novel techniques for performing laparoscopic partial nephrectomy are frequently evaluated in an animal model. | 2005 | 16040101 |
| radiofrequency-enhanced vascular gene transduction and expression for intravascular mr imaging-guided therapy: feasibility study in pigs. | to evaluate the feasibility of radiofrequency (rf)-enhanced vascular gene transduction and expression by using a magnetic resonance (mr) imaging-heating guidewire as an intravascular heating vehicle during mr imaging-guided therapy. | 2005 | 16040894 |
| identification and characterization of neospora caninum cyclophilin that elicits gamma interferon production. | gamma interferon (ifn-gamma) response is essential to the development of a host protective immunity in response to infections by intracellular parasites. neosporosis, an infection caused by the intracellular protozoan parasite neospora caninum, is fatal when there is a complete lack of ifn-gamma in the infected host. however, the mechanism by which ifn-gamma is elicited by the invading parasite is unclear. this study has identified a microbial protein in the n. caninum tachyzoite n. caninum cycl ... | 2005 | 16041025 |
| fluid resuscitation preserves cardiac output but cannot prevent organ damage in a porcine model during 24 h of intraabdominal hypertension. | according to a previous study, a pathologically increased intraabdominal pressure (iap) reduces cardiac output (co) and results in medium- to high-grade organ damage in a porcine model of the abdominal compartment syndrome (acs). the purpose of this study was to evaluate whether fluid resuscitation can preserve organ integrity together with co. we examined 12 domestic pigs with a mean body weight of 48 kg. we used a co2 pneumoperitoneum to increase the iap to 30 mmhg in 6 animals, and the others ... | 2005 | 16044086 |
| comparative distribution of sulphur, thiols and disulphides in the porcine stratum corneum. | biochemical, histochemical and cytochemical analyses were used to determine the sulphur contents and the thiol and disulphide distribution in the stratum corneum (sc) of the wild boar (wb), a large domestic pig breed (dp) and the goettingen miniature pig (gmp). the sulphur contents (% dw) were different in the three animal types (wb: 1.70-1.38 body, 0.54 ear; dp: 0.84-0.53 body, 0.50 ear; gmp: 2.28-2.51 body, 2.66 ear). the results of the histochemical analysis of sh- and -s-s- groups were clear ... | 2005 | 16048751 |
| molecular epidemiology of african swine fever in east africa. | african swine fever (asf) a lethal, viral hemorrhagic disease of domestic pigs, first reported from east africa in 1921, is still widespread in this region. in order to assess field heterogeneity at the regional level, nucleotide sequences corresponding to the c-terminal end of the p72 gene were determined for 77 asf viruses of diverse temporal and species origin occurring in eight east african countries. the number of sites completely conserved across all east african sequences characterized in ... | 2005 | 16052280 |
| spontaneous cure of domestic pigs experimentally infected by trypanosoma brucei gambiense. implications for the control of sleeping sickness. | the existence of a pig reservoir for human african trypanosomosis (hat) due to trypanosoma brucei gambiense complicates the fight against this disease. this study, reports results obtained from pigs, which were inoculated with the blood of a person, suffering from hat in cameroon. the pigs were reared and kept in the shelter from all contact with glossina, and monitored for 188 days. the seroconversion was checked by agglutination assays for trypanosomosis (catt 1.3 and latex/t.b.gambiense). the ... | 2005 | 16076528 |
| transcatheter placement of a low-profile biodegradable pulmonary valve made of small intestinal submucosa: a long-term study in a swine model. | we sought to investigate a placement of a percutaneous low-profile prosthetic valve constructed of small intestinal submucosa in the pulmonary position in a swine model. | 2005 | 16077416 |
| validation of portal vein flow measurement by color flow doppler sonography in a porcine model of septic shock. | to compare portal vein flow values gained by color flow doppler sonography with simultaneously derived data from an ultrasound transit time flow probe. | 2005 | 16086179 |
| beneficial effects of intravenous administration of lipo-prostaglandin e1 on the ischemic gastric tube in pigs. | lipo-prostaglandin e1 (pge1) is a new preparation of pge1 in which it is bound to lipids to slow pge1 release and delay its rate of metabolism. we investigated the change of the blood flow on impaired microcirculation of the ischemic gastric tube in pigs after saline, unmodified pge1, and lipo-pge1 administration. | 2005 | 16087193 |
| the dielectric properties of the cranial skin of five young captive steller sea lions (eumetopias jubatus), and a similar number of young domestic pigs (sus scrofa) and sheep (ovis aries) between 0.1 and 10 ghz. | to aid in the development of a long-range subcutaneous radio frequency identification tag to monitor the fate of sea lion pups, the dielectric properties of the cranial skin of young female otariids, and possible test subjects of similar size and age, or pigs (sus scrofa) and sheep (ovis aries) were obtained over a frequency range of 0.1-10 ghz at the base of their heads where the tag will be implanted. the resulting curves were similar in shape to adult human skin data, but the values were gene ... | 2005 | 16088057 |
| dose response curves for microwave ablation in the cardioplegia-arrested porcine heart. | microwave ablation has been used clinically for the surgical treatment of atrial fibrillation, particularly during valve procedures. however, dose- response curves have not been established for this surgical environment. the purpose of this study was to examine dosimetry curves for the flex 4 and flex 10 microwave devices in an acute cardioplegia-arrested porcine model. | 2005 | 16099735 |
| immune cells in a heterotopic lamb-to-pig bronchial xenograft model. | we developed our porcine model to elucidate the cellular rejection mechanisms of xenografts. bronchial segments from a donor lamb were implanted into domestic pigs. the immunosuppressive regimens consisted of no immusuppression, or of daily oral cyclosporine a (csa) 15 mg/kg, or of everolimus, 1.5 mg/kg, or of both. implants were serially harvested during 17 days. epithelial damage and obliteration were graded histologically, followed by a count of cd4+, cd8+, mhc class ii-expressing cells, and ... | 2005 | 16101731 |
| human endogenous retrovirus expression profiles in samples from brains of patients with schizophrenia and bipolar disorders. | the detection and identification of retroviral transcripts in brain samples, cerebrospinal fluid, and plasma of individuals with recent-onset schizophrenia and schizoaffective disorders suggest that activation or upregulation of distinct human endogenous retroviruses (hervs) may play a role in the etiopathogenesis of neuropsychiatric diseases. to test this hypothesis, we performed a comprehensive microarray-based analysis of herv transcriptional activity in human brains. we investigated 50 repre ... | 2005 | 16103141 |
| in vivo skin absorption and distribution of the nerve agent vx (o-ethyl-s-[2(diisopropylamino)ethyl] methylphosphonothioate) in the domestic white pig. | the purpose of this study was to characterize the skin absorption and distribution of vx (o-ethyl-s-[2 (diisopropylamino)ethyl] methylphosphonothioate) in the domestic pig in order to evaluate the animal as a potential model for assessing pretreatments against toxic anti-cholinesterase compounds. a liquid droplet (equivalent to a 2 x ld50 dose) of radiolabelled vx was applied to the inner ear-skin of each anaesthetized animal. blood and tissue samples (liver, lung, kidney, heart and skin exposur ... | 2005 | 16119248 |
| transepicardial autologous bone marrow-derived mononuclear cell therapy in a porcine model of chronically infarcted myocardium. | cell therapy is becoming a viable strategy to improve revascularization and myocardial function after myocardial injury. we evaluated the effect of bone marrow-derived mononuclear cell (bmmnc) transplantation on collateral vessel development and myocardial function in a porcine model of chronically infarcted heart. | 2004 | 15721847 |
| first record of trichinella pseudospiralis in the slovak republic found in domestic focus. | infection of trichinella spp. is widespread among wildlife in slovakia and the red fox (vulpes vulpes) is the main reservoir of trichinella britovi. trichinella spiralis has been rarely documented in sylvatic and domestic animals of this country. during routine examination of domestic pigs at the slaughter, trichinella larvae were detected by artificial digestion in a domestic pig of a large-scale breeding farm in eastern slovakia. the parasite has been identified by molecular (pcr) and biochemi ... | 2004 | 15725537 |
| spatial and temporal patterns of human african trypanosomosis (hat) transmission risk in the bipindi focus, in the forest zone of southern cameroon. | vector control is an effective and cost-efficient way to disrupt the transmission of human african trypanosomosis (hat); it has nonetheless been little used to date in the disease's foci. with the aim to target trapping more precisely and to develop an optimized vector control system, a transmission risk index was used in the hat focus of bipindi, in the forest zone of southern cameroon. the authors used a simplified version of the index originally developed by laveissière et al. in 1994. the ca ... | 2004 | 15631068 |
| [analysis of presence and difference of sequence of porcine endogenous retrovirus in dna genomes from peripheral blood white cells of pig and mrna in tissues from mini-pigs]. | the aim is to investigate biological features of porcine endogenous retrovirus (perv) of pigs in china and to provide basic parameters for evaluation of biological safety of xenotransplantation from pig to human. in this study, basic biologic features of perv of dna of peripheral blood white cells of 12 species of domestic pigs in china were examined by polymerase chain reaction; analysis of difference of perv gene sequence was investigated by sliver-stained single stranded conformational polymo ... | 2004 | 15636362 |
| radio-frequency tissue ablation in liver trauma: an experimental study. | the liver is the most frequently injured intra-abdominal organ. radio-frequency tissue ablation (rfa) with cooled tip electrodes is here experimentally used for the treatment of liver trauma. a grade iii and a grade iii to iv trauma each were produced in the livers of 10 domestic pigs. rfa was applied around the sites of injury until hemostasis was achieved. the animals were sacrificed at 0, 3, 7, 14, and 21 days and examined. the livers were subjected to histologic and radiologic examination. t ... | 2004 | 15586512 |
| differential effect of experimental hypertension and hypercholesterolemia on adventitial remodeling. | intima-media remodeling, as frequently assessed by changes in the external elastic lamina-to-lumen area (eella), is well-described in coronary artery disease in contrast to adventitial remodeling, especially in the early disease stage. | 2004 | 15591225 |
| feasibility of stent placement in carotid arteries with real-time mr imaging guidance in pigs. | all examinations were performed with approval from the institutional animal care and use committee of columbia university. to assess the feasibility of real-time magnetic resonance (mr) imaging-guided neurovascular intervention in a swine model, the authors placed stents in the carotid arteries of five domestic pigs. seven-french vascular sheaths were placed in the target carotid arteries via femoral access by using active mr tracking. ten nitinol stents (8-10 x 20-40 mm) were successfully deplo ... | 2004 | 15591432 |
| transfemoral catheterization of carotid arteries with real-time mr imaging guidance in pigs. | all procedures and protocols were approved by the institutional animal care and use committee of columbia university. to determine whether transfemoral catheterization of the carotid arteries can be performed entirely with real-time magnetic resonance (mr) imaging guidance, the authors catheterized the carotid arteries in six domestic pigs by using active-tracking catheters and guidewires and mr tracking software created for neurovascular procedures. the carotid arteries were successfully cathet ... | 2004 | 15591433 |
| clinical aspects of percutaneous poisoning by the chemical warfare agent vx: effects of application site and decontamination. | o-ethyl s-(2-diisopropylaminoethyl) methylphosphonothioate (vx) is an extremely toxic organophosphate nerve agent that has been weaponized and stockpiled in a number of different countries, and it has been used in recent terrorist events. it differs from other well-known organophosphate nerve agents in that its primary use is as a contact poison rather than as an inhalation hazard. for this reason, we examined the effects of application site and skin decontamination on vx toxicity in anesthetize ... | 2004 | 15605929 |
| laparoscopic warm renal ischemia in the solitary porcine kidney model. | to determine the effect of a laparoscopic approach on warm renal ischemia in the pig with a solitary kidney. although the maximal safe duration for warm ischemia during open partial nephrectomy is commonly accepted to be 30 minutes, the maximal safe ischemic time during laparoscopic partial nephrectomy has not been previously determined. | 2004 | 15351615 |
| an anaesthetic protocol in the young domestic pig allowing neuromuscular blockade for studies of cardiac function following cardioplegic arrest and cardiopulmonary bypass. | neuromuscular blockade should, for ethical reasons, not be allowed in animal experiments unless the use is strongly motivated. beforehand, the anaesthetic protocol must be documented without muscle relaxation in the species studied. documentation is difficult to obtain from the scientific literature. when focusing on cardiac function over time, in particular, the ideal anaesthetic protocol should cause no or minor alterations in cardiac variables. | 2004 | 15352961 |
| cloning of host-ptp: the only example of a protein-tyrosine-phosphatase the function of which has been lost between rodent and human. | protein-tyrosine-phosphatases (ptp-ases), in concert with protein tyrosine kinases, control various biological activities such as cell growth and differentiation. in rodents, around 40 ptp-ases have been described. functional orthologue for each of these ptp-ases have been identified in human, except for ost-ptp. ost-ptp is a transmembrane ptp-ase with a restricted tissue distribution. in silico analysis on public sequence databases reveals a human ost-ptp gene orthologue that encompasses 21 kb ... | 2004 | 15358244 |
| investigations into growth and differentiation in the cartilage of the condylar process in the domestic pig. a quantitative study of endochondral cartilage growth and cell distribution. | the aim of this study was to examine the extent to which the ratio of the endochondral growth components cell volume increase to matrix production was subject to age-dependent and animal-specific changes per cell in the condylar cartilage of the domestic pig. in addition, it was to be investigated whether the cell distribution in the condylar cartilage and thus the tissue differentiation changes as one aspect of the aging process and whether the differentiation differs from that of primary hyali ... | 2004 | 15378192 |
| laser-assisted vascular end to end anastomosis of elastin heterograft to carotid artery with an albumin stent: a preliminary in vivo study. | laser-assisted end to end vascular anastomosis of an elastin heterograft to native artery may prevent problems associated with currently available vascular synthetic grafts and conventional suture anastomosis. | 2004 | 15389735 |
| effects of hypertonic versus isotonic infusion therapy on regional cerebral blood flow after experimental cardiac arrest cardiopulmonary resuscitation in pigs. | to evaluate the effects of hypertonic, isooncotic, and isotonic infusion therapy on cerebral blood flow (cbf) during and after cardiopulmonary resuscitation (cpr) from experimental cardiac arrest (ca). | 2004 | 15451589 |
| classical swine fever virus strain 'c'. how long is it detectable after oral vaccination? | to determine the persistence period of c-strain vaccine virus in immunized animals, domestic pigs and wild boars were vaccinated orally and killed on different days post vaccinationem (dpv). tissue samples were taken at necropsy from both species for detection of c-strain virus. from domestic pigs nasal swabs and faeces were also collected. during the investigation period (2-12 dpv) vaccine virus could never be detected in nasal secretions and in faeces of vaccinated domestic pigs. in contrast, ... | 2004 | 15458487 |
| attempts to reproduce vacuolar myelinopathy in domestic swine and chickens. | avian vacuolar myelinopathy (avm) was first recognized as a cause of bald eagle (haliaeetus leucocephalus) mortality in 1994 in arkansas (usa) and has since caused over 90 bald eagle and numerous american coot (fulica americana) mortalities in five southeastern states. the cause of avm remains undetermined but is suspected to be a biotoxin. naturally occurring avm has been limited to wild waterbirds, raptors, and one species of shorebird, and has been reproduced experimentally in red-tailed hawk ... | 2004 | 15465715 |
| measurement of portal blood and transjugular intrahepatic portosystemic shunt flow with use of a retrograde thermodilutional catheter. | direct blood flow measurement in the portal vein (pv) and in transjugular intrahepatic portosystemic shunts (tips) holds potential as a means of optimizing shunt creation and predicting outcomes. a retrograde thermodilutional flow measurement catheter was recently designed. the purpose of this study was to validate and optimize the technique of blood flow measurement in the pv with use of this catheter in a swine model of tips. | 2004 | 15466797 |
| intraocular lenses, bacterial adhesion and endophthalmitis prevention: a review. | postoperative endophthalmitis following intraocular lens (iol) implantation is still one of the most feared complications of cataract surgery. bacterial adhesion to iols during their insertion is a prominent etiological factor. polypropylene was the first biomaterial that allowed this relation of cause and effect to be proven. following adhesion, bacteria replicate, congregate and form multiple layers of microcolonies which actually represent the basic structural unit of the biofilm. the bacteri ... | 2004 | 15472388 |
| cyclooxygenase-2 expression in experimental post-transplant obliterative bronchiolitis. | epithelial cell injury, inflammation, progressive fibrosis, and airway obliteration are histological features of post-transplant obliterative bronchiolitis (ob). cyclooxygenase (cox)-2 is expressed in acute and chronic inflammatory responses. our aim was to elucidate the possible role of cox-2 in post-transplant ob by using a heterotopic bronchial porcine model. bronchial allografts from non-related donors were transplanted subcutaneously into 24 random-bred domestic pigs, each weighing about 20 ... | 2004 | 15476277 |
| molecular investigation of hepatitis e virus infection in domestic and miniature pigs used for medical experiments. | hepatitis e virus (hev) infection is highly prevalent among domestic pigs in japan. it has been reported that pig handlers such as farmers and veterinarians are at increased risk of contracting hev infection. pigs are regarded as the most acceptable candidate animals for xenotransplantation and, recently, they are being used as experimental animals. | 2004 | 15479459 |
| phenotypic features of the domestic pigs bred in the roman settlements of pompeii and caralis. | a reconstruction of the morphological features of domestic pigs from two roman settlements is here suggested by means of the study of skeletal and dental remains, with the aim at evaluating their degree of selection in comparison with wild boars. material was formed by 111 bone and tooth fragments and was uncovered during the excavations of polybius' house in pompeii and of roman buildings in the neighbourhood of caralis harbour (sardinia). the remains underwent morphological examination. the er ... | 2004 | 15481159 |
| a novel intestinal anastomotic device in a porcine model. | the purpose of this study was to evaluate a novel, intraluminally deployed anastomotic device (ad). a survival study was conducted in 18 farm pigs. one early subject was excluded and replaced due to premature expiration. six animals were placed in 1 of 3 cohorts, with euthanasia and ad explantation planned at 2, 4, and 6 weeks. a distal small intestinal side-side [functional end-end] anastomosis using the ad was performed via midline laparotomy. fluoroscopy with double-contrast dilute barium and ... | 2004 | 15481291 |
| trichinella pseudospiralis foci in sweden. | in sweden, the prevalence of trichinella infection in domestic pigs has greatly decreased since the 1970s, with no reports in the past 4 years. however, infected wild animals continue to be found. the objective of the present study was to identify the species of trichinella present in animals of sweden, so as to contribute to the knowledge on the distribution area and hosts useful for the prevention and control of this zoonosis. in the period 1985-2003, trichinella larvae were detected in the mu ... | 2004 | 15482889 |
| [analysis of gene expression profiles in heart tissues from two breeds of pigs]. | to study the expression profiles in the heart tissues of domestic pigs,five un-normalized cdna libraries from danish adult female landrace heart, biceps femoris, aorta, left ventricle tissues and chinese adult female erhualian heart tissue were constructed. totally 35 180 expressed sequence tags (ests) were randomly sequenced. using functional clustering and statistic methods, three gene clusters and 47 genes highly expressed in landrace heart tissue were found. these genes are corresponding to ... | 2004 | 15490873 |
| only transient increase of vascular growth factors and microvascular density after percutaneous myocardial laser. | we tested the hypothesis that percutaneous myocardial laser may stimulate microvascular growth in areas surrounding the laser channels. | 2004 | 15492594 |
| diurnal rhythms of pinealocyte ultrastructure, pineal serotonin content and plasma melatonin level in the domestic pig. | the study was conducted to investigate diurnal changes in pinealocyte ultrastructure, pineal serotonin content and plasma melatonin concentration in the domestic pig. the immature pigs (n=24) were kept under a cycle of 12 h light : 12 h dark, with a photophase between 0800 and 2000. during the photophase the animals were exposed to direct sunlight. after four weeks the gilts were slaughtered at 0900, 1400, 2100 and 0200. the pineals were removed and divided into two parts - one for quantitative ... | 2004 | 15493576 |
| pathological changes in sarcocystis infection in domestic pigs (sus scrofa). | 2004 | 15501157 | |
| fluid resuscitation from severe hemorrhagic shock using diaspirin cross-linked hemoglobin fails to improve pancreatic and renal perfusion. | fluid resuscitation from hemorrhagic shock is intended to abolish microcirculatory disorders and to restore adequate tissue oxygenation. diaspirin cross-linked hemoglobin (dclhb) is a hemoglobin-based oxygen carrier (hboc) with vasoconstrictive properties. therefore, fluid resuscitation from severe hemorrhagic shock using dclhb was expected to improve perfusion pressure and tissue perfusion of kidneys and pancreas. | 2004 | 15504197 |
| co-circulation of two genetically distinct viruses in an outbreak of african swine fever in mozambique: no evidence for individual co-infection. | in 1998, domestic pigs originating from villages within a 40 km radius of ulongwe in the northern tete province of mozambique were held in a quarantine facility for a 3-month period prior to their importation into south africa. eight of a total of 25 pigs died within the first 3 weeks of quarantine of what appeared clinically and on post mortem examination to be african swine fever (asf). organs were collected and preserved in formol-glycerosaline and the presence of asf virus in these specimens ... | 2004 | 15504588 |
| inhibitory g protein overexpression provides physiologically relevant heart rate control in persistent atrial fibrillation. | the need for new treatment strategies for cardiac arrhythmias has motivated our continuing development of gene therapeutic options. previously, we reported a decreased heart rate in an acute model of atrial fibrillation after atrioventricular nodal gene transfer. here, we expand those observations to persistent atrial fibrillation and severe heart failure. | 2004 | 15505099 |
| comparative map between the domestic pig and dog. | cross-species chromosome painting with probes derived from flow-sorted dog and human chromosomes was used to construct a high-resolution comparative map for the pig. in total 98 conserved autosomal segments between pig and dog were detected by probes specific for the 38 autosomes and x chromosome of the dog. further integration of our results with the published human--dog and cat--dog comparative maps, and with data from comparative gene mapping, increases the resolution of the current pig--huma ... | 2004 | 15520883 |
| routes of transmission of swine hepatitis e virus in pigs. | hepatitis e virus (hev) is believed to be transmitted by the fecal-oral route in pigs. to date, in experiments, hev has been transmitted successfully only by the intravenous or intrahepatic route. to assess the route of hev transmission, 27 pigs were separated into nine groups of three pigs. positive-control pigs were inoculated intravenously with swine hev and served as the source of hev for the other groups. uninoculated contact pigs were placed in the positive-control group. on three consecut ... | 2004 | 15528694 |
| renal tolerance to prolonged warm ischemia time in a laparoscopic versus open surgery porcine model. | to our knowledge the effects of renal warm ischemia (wi) during laparoscopic vs open surgery have not been investigated. decreased renal blood flow during pneumoperitoneum may precondition the kidney to tolerate longer wi time. traditionally 30 minutes has defined the limit of renal wi time in open surgery. however, recent reports show renal function recovery at wi times of 45 to 120 minutes. we assessed renal function recovery after prolonged wi during laparoscopic vs open surgery in a solitary ... | 2004 | 15538293 |
| lung biopsy with a 12-gauge cutting needle is possible using an insertion sheath in animal models. | the volume of lung tumor core biopsy specimens has been restricted because of concerns for complications such as bleeding and air leakage. in this animal experiment, we investigated the possibility of larger bore biopsies through the peripheral lung parenchyma. | 2004 | 15561575 |
| [prevalence of hemorrhagic fever with renal syndrome virus in domestic pigs: an epidemiological investigation in shandong province]. | to investigate the epidemiological significance of hemorrhagic fever with renal syndrome virus (hfrsv) infection in domestic pigs in shandong province, and study the role of domestic pigs in the prevalence of hfrs. | 2004 | 15567780 |
| an investigation into natural resistance to african swine fever in domestic pigs from an endemic area in southern africa. | a population of domestic pigs in northern mozambique with increased resistance to the pathogenic effects of african swine fever (asf) virus was identified by the high prevalence of circulating antibodies to asf virus. an attempt was made to establish whether the resistance in this population was heritable. some of these pigs were acquired and transported to a quarantine facility and allowed to breed naturally. offspring of the resistant pigs were transferred to a high security facility where the ... | 2004 | 15861893 |
| smooth-muscle regeneration after electrosurgical endopyelotomy in a porcine model as confirmed by electron microscopy. | endopyelotomy is the preferred treatment for ureteropelvic junction (upj) obstruction because of its short operating time, limited morbidity, fast recovery, and reasonable efficacy. we used tissue and immunohistochemistry staining and electron microscopy to look at the muscle regeneration following an endopyelotomy incision in a porcine model. | 2004 | 15801366 |
| foraging behaviour in domestic pigs (sus scrofa): remembering and prioritizing food sites of different value. | this experiment investigated whether domestic pigs can remember the locations of food sites of different relative value, and how a restricted retrieval choice affects their foraging behaviour. nine juvenile female pigs were trained to relocate two food sites out of a possible eight in a spatial memory task. the two baited sites contained different amounts of food and an obstacle was added to the smaller amount to increase handling time. on each trial, a pig searched for the two baited sites (sea ... | 2004 | 15871038 |
| assessment of subacute inflammatory and proliferative response to coronary stenting in a porcine model by local gene expression studies and histomorphometry. | the aim of the study was to analyse inflammatory and proliferative response early after coronary stenting by angiography, histomorphometry and local gene expression analysis using quantitative rt-pcr. therefore, eight german domestic pigs underwent stenting of the left coronary artery. selective coronary angiography was performed after 14 days. explanted coronary arteries were examined histomorphometrically after methacrylate-embedding. snap-frozen samples were examined for local gene expression ... | 2004 | 14615159 |
| description and evaluation of a ventriculo-coronary artery bypass device that provides bi-directional coronary flow. | the objective of this study was to assess acute patency of a new myocardial revascularization device that connects the left ventricular cavity to a coronary artery (termed ventriculo-coronary artery bypass, vcab) thereby providing proximal and distal blood flow from the site of the anastomosis. | 2004 | 14690731 |
| porcine wound models for skin substitution and burn treatment. | skin regeneration is an important field of tissue engineering. especially in larger burns and chronic wounds, present treatments are insufficient in preventing scar formation and promoting healing. initial screening of potentially interesting products for skin substitution is usually done by in vitro tests. before entering the clinic, however, in vivo studies in immunocompetent animals are necessary to prove efficacy and provide information on safety aspects. we have obtained extensive experienc ... | 2004 | 14697858 |
| spontaneous gasping generates cardiac output during cardiac arrest. | to measure stroke volumes coincident with spontaneous gasping during untreated ventricular fibrillation and to evaluate the effects of gasping. | 2004 | 14707585 |
| comprehensive evaluation of ureteral healing after electrosurgical endopyelotomy in a porcine model: original report and review of the literature. | endopyelotomy (ep) has yet to equal the success achieved with open dismembered pyeloplasty. to understand better the ureteral response to ep we performed a timed histopathological evaluation of the porcine ureter after acucise (applied medical, rancho santa margarita, california) ep. | 2004 | 14713843 |
| spatial comparison between wall shear stress measures and porcine arterial endothelial permeability. | a better understanding of how hemodynamic factors affect the integrity and function of the vascular endothelium is necessary to appreciate more fully how atherosclerosis is initiated and promoted. a novel technique is presented to assess the relation between fluid dynamic variables and the permeability of the endothelium to macromolecules. fully anesthetized, domestic swine were intravenously injected with the albumin marker evans blue dye, which was allowed to circulate for 90 min. after the an ... | 2004 | 14715506 |
| pcr identification of beef, sheep, goat, and pork in raw and heat-treated meat mixtures. | a pcr assay has been developed for the specific and qualitative detection of pork (sus scrofa domesticus), beef (bos taurus), sheep (ovis aries), and goat (capra hircus) in raw and heat-treated meat mixtures. a forward common primer was designed on a conserved dna sequence in the mitochondrial 12s ribosomal rna gene (rrna), and reverse primers were designed to hybridize on species-specific dna sequences of each species considered. the different sizes of the species-specific amplicons, separated ... | 2004 | 14717369 |
| biological transmission of vesicular stomatitis virus (new jersey serotype) by simulium vittatum (diptera: simuliidae) to domestic swine (sus scrofa). | the role of hematophagous arthropods in vesicular stomatitis virus (new jersey serotype; vsv-nj) transmission during epizootics has remained unclear for decades in part because it has never been shown that clinical or subclinical disease in a livestock host results from the bite of an infected insect. in this study, we investigated the ability of vsv-nj-infected black flies (simulium vittatum zetterstedt) to transmit the virus to domestic swine, sus scrofa l. experimental evidence presented here ... | 2004 | 14989350 |
| 3d pulmonary perfusion mri and mr angiography of pulmonary embolism in pigs after a single injection of a blood pool mr contrast agent. | the purpose of this study was to assess the feasibility of contrast-enhanced 3d perfusion mri and mr angiography (mra) of pulmonary embolism (pe) in pigs using a single injection of the blood pool contrast gadomer. pe was induced in five domestic pigs by injection of autologous blood thrombi. contrast-enhanced first-pass 3d perfusion mri (te/tr/fa: 1.0 ms/2.2 ms/40 degrees; voxel size: 1.3 x 2.5 x 4.0 mm3; ta: 1.8 s per data set) and high-resolution 3d mra (te/tr/fa: 1.4 ms/3.4 ms/40 degrees; vo ... | 2004 | 14997336 |
| changes of lymphatic flow in case of pancreatic duct obstruction in the pig--as a model of pancreatic cancer. | to investigate the lymph network change in pancreatic duct obstruction in pigs as a model of pancreatic cancer invading pancreatic duct, six domestic pigs weighing 17-40 kg underwent surgery as protocol. two of them were controls, and the others underwent ligation of the pancreatic duct as a model of ductal obstruction. a ch 40 and lipiodol mixture was injected in their pancreas at 7 or 21 days after first operation. radiographic examination had been also performed. five or 14 days later, they w ... | 2004 | 15000259 |
| routine vascular control using the hem-o-lok clip in laparoscopic nephrectomy: animal study and clinical application. | during laparoscopic nephrectomy (lpn), a stapling device is often used for vascular control, especially of the renal vein. herein, we report our experience using a polymer clip (hem-o-lok) for routine control of the vessels during lpn in the animal and clinical setting. | 2004 | 15006060 |
| needle-based ablation of renal parenchyma using microwave, cryoablation, impedance- and temperature-based monopolar and bipolar radiofrequency, and liquid and gel chemoablation: laboratory studies and review of the literature. | small renal tumors are often serendipitously detected during the screening of patients for renal or other disease entities. rather than perform a radical or partial nephrectomy for these diminutive lesions, several centers have begun to explore a variety of ablative energy sources that could be applied directly via a percutaneously placed needle-like probe. to evaluate the utility of such treatment for small renal tumors/masses, we compared the feasibility, regularity (consistency in size and sh ... | 2004 | 15006061 |
| effect of food consistency on temporomandibular joint morphology: an experimental study in pigs. | to investigate whether there are any correlations between increased masticatory loading, degree of tooth wear, and the size, form, and macroscopic surface of the temporomandibular joints (tmjs). | 2004 | 15022535 |
| downregulation of n-cadherin in the neointima stimulates migration of smooth muscle cells by rhoa deactivation. | the aim of the study was to analyze whether cadherin- and rho-family gtpases-mediated dynamic rearrangement of cell-cell adhesion play an important role during human arterial smooth muscle cell (hasmc) migration. | 2004 | 15023568 |
| respiratory changes during prolonged increased intra-abdominal pressure in pigs. | increased intra-abdominal pressure (iap) elevates thoracic pressure and airway pressures and reduces lung compliance in humans and laboratory animals. we studied respiratory alterations and arterial blood gas changes in pigs with iap maintained at 20 mmhg or 30 mmhg for 3 h. | 2004 | 15025609 |
| prevalence of porcine endogenous retrovirus in domestic pigs in japan and its potential infection in dogs xenotransplanted with porcine pancreatic islet cells. | the prevalence of porcine endogenous retrovirus (perv) proviral dna among various pig breeds raised in japan was investigated by polymerase chain reaction (pcr). moreover, potential infection of perv was investigated by pcr and reverse transcriptase-polymerase chain reaction (rt-pcr) in experimentally induced diabetic dogs (n=5) implanted with the diffusion chamber type bio-artificial endocrine pancreas (bio-aep) containing porcine pancreatic endocrine (pe) cells. no immunosuppressant was used a ... | 2004 | 15031539 |
| [histological investigation of the micromorphological effects of the application of a laser needle--results of an animal experiment]. | in an experimental animal study (sus scrofa domesticus) we investigated the effects of the new technique of laser needle stimulation (wavelength: 685 nm; energy density: 4.6 kj/cm2 per point; application duration: 20 min). the results revealed changes in microcirculatory parameters of the skin resulting in an increase in blood flow. however, the quality and intensity of the laser light did not induce micromorphological alterations in the skin. | 2004 | 15032490 |
| novel herpesviruses of suidae: indicators for a second genogroup of artiodactyl gammaherpesviruses. | five novel herpesviruses were identified in suid species from africa (common warthog, phacochoerus africanus) and south-east asia (bearded pig, sus barbatus; babirusa, babyrousa babyrussa) by detection and analysis of their dna polymerase genes. three of the novel species, p. africanus cytomegalovirus 1, p. africanus lymphotropic herpesvirus 1 (pafrlhv-1) and s. barbatus lymphotropic herpesvirus 1 (sbarlhv-1), were closely related to known beta- (porcine cytomegalovirus) and gammaherpesviruses [ ... | 2004 | 15039528 |
| prevalence of antibodies to hepatitis e virus among apparently healthy humans and pigs in bali, indonesia: identification of a pig infected with a genotype 4 hepatitis e virus. | in indonesia where hepatitis e virus (hev) is believed to be highly endemic, only three outbreaks of hev transmission have been documented to date in restricted areas (west kalimantan and east java). a total of 1,115 serum samples collected from apparently healthy individuals in bali, lombok, and surabaya in indonesia in 1996 where epidemic hev transmissions have never been reported, were tested for igg class antibodies to hev (anti-hev). in bali, anti-hev was detected in 20% (54/276) of the tes ... | 2004 | 15042646 |
| linkage disequilibrium in the domesticated pig. | this study investigated the extent of linkage disequilibrium (ld) in two genomic regions (on chromosomes 4 and 7) in five populations of domesticated pigs. ld was measured with d' and tested for significance with the fisher exact test. effects of genetic (linkage) distance, chromosome, population, and their interactions on d' were tested both through a linear model analysis of covariance and by a theoretical nonlinear model. the overall result was that (1) the distance explained most of the vari ... | 2004 | 15082558 |
| new metallic mr stents for artifact-free coronary mr angiography: feasibility study in a swine model. | the objective of this study was to investigate the potential for artifact-free coronary magnetic resonance angiography (cmra) in the presence of dedicated metallic mr stents in vitro and in a swine model. | 2004 | 15087718 |
| epidemiological study on porcine circovirus type 2 (pcv2) infection in the european wild boar (sus scrofa). | porcine circovirus type 2 (pcv2) is considered as the causative agent of postweaning multisystemic wasting syndrome (pmws) in domestic pigs, where the virus is ubiquitous as evidenced by serological surveys. we present the results of the first nationwide sero-survey on the presence of pcv2 antibodies in european wild boars, and report the first pmws case in a wild boar from spain. sera from 656 hunter harvested wild boars from 45 different geographical sites and 22 additional imported animals we ... | 2004 | 15099500 |
| immunogenicity and t cell recognition in swine of foot-and-mouth disease virus polymerase 3d. | immunization of domestic pigs with a vaccinia virus (vv) recombinant expressing foot-and-mouth disease virus (fmdv) 3d protein conferred partial protection against challenge with infectious virus. the severity reduction of the clinical symptoms developed by the challenged animals occurred in the absence of significant levels of anti-3d circulating antibodies. this observation suggested that the partial protection observed was mediated by the induction of a 3d-specific cellular immune response. t ... | 2004 | 15110524 |
| surgical construction of an in vivo carotid siphon model to test neurovascular devices. | we developed an animal model to evaluate vascular trauma induced by endovascular devices that are proposed for the treatment of cerebrovascular diseases. | 2004 | 15113480 |
| acute myocardial infarction: contrast-enhanced multi-detector row ct in a porcine model. | to assess the role of contrast material-enhanced retrospectively electrocardiographically (ecg) gated multi-detector row computed tomography (ct) in the detection of acute myocardial infarction in a porcine model of total coronary occlusion. | 2004 | 15118118 |
| emerging encephalitogenic viruses: lyssaviruses and henipaviruses transmitted by frugivorous bats. | three newly recognized encephalitogenic zoonotic viruses spread from fruit bats of the genus pteropus (order chiroptera, suborder megachiroptera) have been recognised over the past decade. these are: hendra virus, formerly named equine morbillivirus, which was responsible for an outbreak of disease in horses and humans in brisbane, australia, in 1994; australian bat lyssavirus, the cause of a severe acute encephalitis, in 1996; and nipah virus, the cause of a major outbreak of encephalitis and p ... | 2004 | 15119765 |
| the effects of birth weight and postnatal growth patterns on fat depth and plasma leptin concentrations in juvenile and adult pigs. | low birth weight is associated with altered adipose tissue deposition and regulation of leptin production. this study determined the effects of naturally occurring variations in birth weight in pigs on postnatal growth patterns, body fat depth and plasma leptin and other hormone concentrations. low (< 1.47 kg) and high (> 1.53 kg) birth weight piglets were studied at 3 months (juvenile; n= 47) and 12 months of age (young adult; n= 17). at each age, arterial and venous catheters were inserted und ... | 2004 | 15121800 |
| delayed portal vein thrombosis after experimental radiofrequency ablation near the main portal vein. | portal venous blood flow may protect adjacent tumour cells from thermal destruction with radiofrequency ablation (rfa). this study aimed to investigate the local effect of rfa on the main portal vein branch, and the completeness of cellular ablation in its vicinity, with or without a pringle manoeuvre using a porcine model. | 2004 | 15122617 |
| a novel population of calretinin-positive neurons comprises reelin-positive cajal-retzius cells in the hippocampal formation of the adult domestic pig. | calretinin-containing neurons in the hippocampal formation, including the subiculum, presubiculum, parasubiculum, and entorhinal cortex, were visualized with immunocytochemistry. calretinin immunoreactivity was present exclusively in non-principal cells. the largest immunoreactive cell population was found in the outer half of the molecular layer of the dentate gyrus and in the stratum lacunosum-moleculare of ammon's horn. a proportion of these cells were also immunoreactive for reelin, a cajal- ... | 2004 | 15132437 |
| interaction between a perfluorocarbon emulsion and radiographic contrast media. | this study evaluated specially designed perfluorocarbon (pfc) emulsions as blood substitutes in case of induced ischemia of the left heart ventricle in healthy farm pigs. two hundred ml of perfluorocarbon emulsion were infused while 200 ml of blood were simultaneously drawn. radiographic contrast media were given to aid placement of balloon catheters in the left coronary artery. histopathological analysis showed that right heart failure caused the deaths of both pigs. particles (up to>3 micro) o ... | 2004 | 15152157 |
| splanchnic metabolism during gut ischemia and short-term endotoxin and hemorrhagic shock as evaluated by intravasal microdialysis. | the splanchnic area is of considerable interest in different types of shock. to characterize the metabolic changes in the splanchnic region in response to different types of shock we used a model where shock-induced metabolic changes in the splanchnic region were studied by the use of intravasal microdialysis. 23 anesthetized domestic pigs were randomized into four groups: group i, serving as controls (n = 5); group ii, mesenteric ischemia for 180 followed by 120 min of reperfusion (n = 5); grou ... | 2004 | 15167688 |
| ultrasound strain imaging of altered myocardial stiffness: stunned versus infarcted reperfused myocardium. | in this study we evaluate the diastolic deformation of ischemic/reperfused myocardium and relate this deformation to tissue elastic properties. | 2004 | 15173032 |
| load dependence of cardiac output in biventricular pacing: right ventricular pressure overload in pigs. | the effect of biventricular pacing on stroke volume is believed to be dependent on right ventricular/left ventricular delay, but effects in individual patients are unpredictable. this variability may reflect relative right and left ventricular volume and/or pressure overloads. accordingly, we tested the hypothesis that the relation of cardiac output to right ventricular/left ventricular delay is load dependent in a pig model of pulmonary stenosis. | 2004 | 15173728 |
| initial study of arthropod succession on pig carrion in a central european urban habitat. | we conducted a carrion succession study within a restricted urban backyard in the city of vienna, austria (16 degrees 22'e, 48 degrees 12'n) from may to november 2001 to analyze sequence and composition of the local carrion visiting fauna. two medium sized clothed domestic pig carcasses (sus scrofa linnaeus), were used as surrogate human models. in total, 42 arthropod species from the families calliphoridae, sarcophagidae, sepsidae, piophilidae, muscidae, fanniidae, sphaeroceridae, phoridae, dro ... | 2004 | 15185958 |
| in vitro coronary artery imaging with sixteen-slice helical computed tomography. | to determine the benefits of submillimeter coronary computed tomography (ct) angiography in vitro. | 2004 | 15191099 |
| detection and genetic characterization of porcine circovirus type 2 (pcv2) in pigs from croatia. | porcine circovirus type 2 (pcv2) from the circoviridae family has recently been associated with two serious diseases of swine, post-weaning multisystemic wasting syndrome (pmws) and porcine dermatitis and nephropathy syndrome (pdns). during 2002, several outbreaks of clinical disease in pigs with weights ranging from 10 to 70 kg occurred on four farms in different locations in croatia. the signs were consistent with pmws and pdns. apart from progressive weight loss, pneumonia and/or diarrhoea, m ... | 2004 | 15196907 |
| an isoenzyme survey of trypanosoma brucei s.l. from the central african subregion: population structure, taxonomic and epidemiological considerations. | in order to improve our knowledge about the taxonomic status and the population structure of the causative agent of human african trypanosomiasis in the central african subregion, 169 newly isolated stocks, of which 16 came from pigs, and 5 reference stocks, were characterized by multilocus enzyme electrophoresis, for 17 genetic loci. we identified 22 different isoenzyme profiles or zymodemes, many of which showed limited differences between them. these zymodemes were equated to multilocus genot ... | 2004 | 15206467 |
| comparison of methods of temperature measurement in swine. | the purpose of these experiments was to test the equivalence of pulmonary artery, urinary bladder, tympanic, rectal and femoral artery methods of temperature measurement in healthy and critically ill swine under clinical intensive care unit (icu) conditions using a prospective, time series design. first, sensors were tested for error and sensitivity to change in temperature with a precision-controlled water bath and a laboratory-certified digital thermometer for temperatures 34-42 degrees c. the ... | 2004 | 15207041 |
| african swine fever virus proteins involved in evading host defence systems. | african swine fever virus (asfv) can cause an acutely fatal haemorrhagic fever in domestic pigs although in its natural hosts, warthogs, bushpigs and the soft tick vector, ornithodoros moubata, asfv causes inapparent persistent infections. the virus is a large, cytoplasmic, double-stranded dna virus which has a tropism for macrophages. as it is the only member of the asfarviridae family, asfv encodes many novel genes not encoded by other virus families. the ability of the virus to persist in its ... | 2004 | 15207450 |
| betaine improves growth, but does not induce whole body or hepatic palmitate oxidation in swine (sus scrofa domestica). | dietary betaine may reduce carcass fat in growing pigs. we explored the effects of betaine on short-term growth and in vivo and in vitro fatty acid oxidation. pigs were housed in metabolism crates and fed diets containing either 0% (control), 0.125% or 0.5% betaine at 80% of ad libitum energy intake. fatty acid oxidation was measured during intravenous infusions of 1-(13)c-palmitate and in hepatocytes incubated in the presence or absence of betaine and carnitine. co2 and palmitate isotopic enric ... | 2004 | 14720598 |
| functional and phylogenetic analyses of a melanocortin-4 receptor mutation in domestic pigs. | the melanocortin-4 receptor (mc4r), a g protein-coupled seven-transmembrane receptor, which is expressed in the brain, plays an important role in the control of mammalian energy homeostasis. a missense mutation (asp298asn) was identified in the porcine mc4r gene, which is associated with growth and food intake traits. the asn298 mutation occurs within a highly conserved motif, npliy, of all members of g protein-coupled receptors; whereas, asp298 is conserved in all five melanocortin receptor sub ... | 2004 | 14732454 |
| experimental disc degeneration due to endplate injury. | the aim of this study was to create an experimental model of disc degeneration that closely mimicked human disc degeneration. in six domestic pigs, an l4 cranial endplate perforation into the nucleus pulposus was made. three months postoperatively, compressive testing was performed on the l2-l4 motion segments, and intradiscal pressure was measured in the intervening discs. histochemical and morphologic examinations were made on the excised degenerated and adjacent discs. a significant reduction ... | 2004 | 14734978 |
| long-term retention of endoscopically placed hydrogel prostheses at the lower esophageal sphincter in pigs. | using flexible endoscopic methods, hydrogel prostheses can be safely placed, retained for long periods of time, and removed from the esophageal submucosa of pigs. this new technique may have future applications in the treatment of gastroesophageal reflux disease in selected situations. | 2004 | 14752644 |
| [trichinellosis outbreaks in spain (1990-2001)]. | trichinellosis is a helminth infection having a wide geographical distribution. it is acquired by ingestion of raw or undercooked meat infected with trichinella spp. the present work reviews the human trichinellosis outbreaks recorded in spain during 1990-2001, taking into account both the geographical distribution and source of the infection. | 2004 | 14756987 |
| how long can we preserve the pulmonary graft inside the nonheart-beating donor? | the use of lungs from nonheart-beating donors (nhbd) might significantly alleviate the organ shortage. extending the preharvest interval in nhbd would facilitate distant organ retrieval. we hypothesized that prolonged topical cooling inside nhbd after 60 minutes of initial warm ischemia would not affect the pulmonary graft. | 2004 | 14759412 |