Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| volumetric perfusion ct using prototype 256-detector row ct scanner: preliminary study with healthy porcine model. | this is a preliminary demonstration of volumetric perfusion ct of the brain in domestic pigs by using a prototype 256-detector row ct. scan range is approximately 100 mm in the craniocaudal direction with 0.5-mm section thickness. the 256-detector row ct is an easily available imaging technique that can provide volumetric cine imaging, ct angiography, and perfusion ct in a wide craniocaudal coverage simultaneously. | 2005 | 16286398 |
| pps-peg surface coating to reduce thrombogenicity of small diameter eptfe vascular grafts. | patency failure of small vascular synthetic grafts is still a major problem for coronary and peripheral revascularization. thus, three new surface coatings of small synthetic grafts were tested in an acute pig model to evaluate their thrombogenicity (extracorporeal arterio-venous shunt) and in a chronic rat model to evaluate the tissue reaction they induced (subcutaneous implantation). | 2005 | 16288437 |
| histologic effects of laser-assisted topical anesthesia in a porcine model. | a handheld laser device that removes the stratum corneum, the major barrier to transdermal absorption, has recently been approved to assist with topical anesthesia before painful procedures such as intravenous cannulation. the authors assessed the cutaneous histomorphologic effects of the laser device and the ability of the laser-treated skin to resist infection in a porcine model. | 2005 | 16293894 |
| endothelial dysfunction after lactated ringer's solution resuscitation for hemorrhagic shock. | endothelial dysfunction is presumed to occur after hemorrhagic shock and resuscitation. this study uses a novel large-animal model to evaluate the effects of diverse resuscitation regimens on endothelial function. | 2005 | 16294066 |
| seroprevalence of toxoplasma gondii infection in domestic pigs reared under different management systems in zimbabwe. | serum samples from 474 domestic pigs (sus scrofa) from zimbabwe were tested for anti-toxoplasma gondii igg antibodies using the indirect fluorescent antibody test. the results showed that t. gondii infection is widespread in zimbabwean pigs. seroprevalence was lowest in fattening pigs from large and small-scale commercial farms that practise good hygiene (19.75% of 238) and highest in backyard scavenging pigs (35.71% of 70). only 11.7% (11) of the 127 positive samples had titres of > or = 1:400 ... | 2005 | 16300191 |
| effects of combined administration of vasopressin, epinephrine, and norepinephrine during cardiopulmonary resuscitation in pigs. | synergistic effects of epinephrine and vasopressin may be of benefit during cardiopulmonary resuscitation. however, cerebral perfusion was decreased when epinephrine was combined with vasopressin compared with vasopressin alone. although a combined infusion of norepinephrine and vasopressin improves hemodynamic variables compared with norepinephrine alone during sepsis, it is unknown whether norepinephrine in addition to vasopressin and epinephrine changes vital organ perfusion during cardiopulm ... | 2005 | 16276184 |
| cariporide minimizes adverse myocardial effects of epinephrine during resuscitation from ventricular fibrillation. | epinephrine given during closed-chest resuscitation increases blood flow across the coronary and cerebral circuits. however, epinephrine worsens reperfusion arrhythmias and intensifies postresuscitation myocardial dysfunction. we investigated whether cariporide-a selective sodium-hydrogen exchanger isoform-1 inhibitor-could ameliorate such adverse effects without diminishing its vasopressor actions. | 2005 | 16276186 |
| third prize: prostaglandin e(2)-3 receptor is involved in ureteral contractility in obstruction. | we previously found that prostaglandin (pg) e2 contracts acutely obstructed ureters while relaxing normal ureters. this study investigated the procontractile effects of the pg ep3 receptor in pge(2)-mediated contractility in obstructed and normal porcine ureters. | 2005 | 16283845 |
| comparison of running and interrupted vesicourethral anastomoses in a porcine model. | to compare running and interrupted suturing techniques for porcine vesicourethral anastomosis with regard to procedure time, histopathologic effects, and leakage. | 2005 | 16283849 |
| evaluation of hydrogel tissue sealant in porcine laparoscopic partial-nephrectomy model. | laparoscopic partial nephrectomy (lpn) is technically challenging with a steep learning curve, primarily because techniques used to control bleeding on the cut surface of the kidney can be ineffective, inconsistent, or challenging. hemostatic techniques can include intracorporeal suturing, vascular coagulation (argon-beam coagulator, bipolar cautery, laser), and application of various tissue sealants. there is no uniformity of opinion regarding which hemostatic technique is optimal for this appl ... | 2005 | 16283851 |
| cytokine response to surgical stress: comparison of pure laparoscopic, hand-assisted laparoscopic, and open nephrectomy. | laparoscopic surgery has been shown to induce less immune suppression than open surgery, presumably because there is less tissue trauma, a factor that may impact oncologic-disease control. the objective of this study was to compare the cytokine and stress response associated with pure laparoscopic, hand-assisted laparoscopic (hal), and open nephrectomy. | 2005 | 16283854 |
| assessment of in vivo mr imaging compared to physical sections in vitro--a quantitative study of brain volumes using stereology. | the object of the present study was to compare stereological estimates of brain volumes obtained in vivo by magnetic resonance imaging (mri) to corresponding volumes from physical sections in vitro. brains of ten domestic pigs were imaged using a 3-t scanner. the volumes of different brain compartments were obtained from mr images by two observers and from physical sections using the cavalieri estimator in combination with point counting. paired t tests revealed no significant differences betwee ... | 2005 | 15862205 |
| impedance-gradient electrode reduces skin irritation induced by transthoracic defibrillation. | a new type of disposable external defibrillation electrode has been developed to reduce the skin irritation commonly associated with defibrillation and synchronised cardioversion. this design employs an impedance gradient to reduce the proportion of current delivered to the electrode periphery. the temperature distribution under the new electrode was compared with that of four other types of commercially available electrodes after repeated high-energy biphasic defibrillation discharges to domest ... | 2005 | 15865132 |
| experimental study on fluorescent microspheres as a tracer for sentinel node detection. | common tracers for sentinel node navigation surgery are blue dye and technetium-99m-labelled colloids. however, in most esophageal or lung cancer patients, it is impossible to detect the sentinel node among mediastinal nodes by blue dye because of the anthracotic pigmentation of mediastinal nodes. the use of technetium-99m-labelled colloids requires a special facility, while a large hot-spot at the injection site prevents detection of the sentinel node around the primary lesion. to overcome thes ... | 2005 | 15868914 |
| effects of perfluorohexan vapor on gas exchange, respiratory mechanics, and lung histology in pigs with lung injury after endotoxin infusion. | inhaled perfluorohexan vapor has been shown to improve gas exchange and pulmonary mechanics in oleic acid- and ventilator-induced lung injury. however, in the clinical setting, lung injury frequently occurs in the context of systemic inflammation and consecutive lung injury, which may be induced experimentally by intravenous administration of endotoxin. the authors studied whether vaporized perfluorohexan is efficacious during endotoxin-induced lung injury in domestic pigs. | 2005 | 16129984 |
| nictitating membrane as a potentially useful postmortem diagnostic specimen for classical swine fever. | the gold standard for diagnosis of classical swine fever (csf) is cell culture virus isolation combined with reverse transcriptase-polymerase chain reaction (rt-pcr) and fluorescent antibody test (fat) in cryosections of tonsils, spleen, various lymph nodes, ileum, and kidney. autolytic and heterolytic samples render correct fat evaluation difficult and can even yield false-negative or ambiguously positive results. to extend the spectrum of csf diagnostic specimens, the authors tested whether th ... | 2005 | 16130991 |
| levosimendan improves postresuscitation myocardial dysfunction after beta-adrenergic blockade. | in earlier studies, we found that a nonselective beta-adrenergic blocking agent, propranolol, facilitated cardiac resuscitation, reduced postresuscitation myocardial ectopy, and improved postresuscitation survival. however, the potential adverse effects and specifically the negative inotropic actions of propranolol prompted our further investigation of the potential value of a non-beta-adrenergic inotropic drug, levosimendan, in conjunction with propranolol, for minimizing postresuscitation myoc ... | 2005 | 16131457 |
| laparoscopic liver resection using radio frequency ablation in a porcine model. | the aim of this study was to assess the feasibility, efficacy, and safety of laparoscopic left lateral lobe resection, using radiofrequency ablation (rfa) with internally cooled tip electrodes, in a porcine model. | 2005 | 16132328 |
| evaluation of intra-abdominal pressures and gas embolism during laparoscopic partial nephrectomy in a porcine model. | gas embolization is a well documented complication of laparoscopic surgery. we evaluated the association of gas embolization with increased intra-abdominal pressure (iap) in the porcine model during laparoscopic partial nephrectomy with real-time transesophageal echocardiography. | 2005 | 16145470 |
| oxidant injury occurs rapidly after cardiac arrest, cardiopulmonary resuscitation, and reperfusion. | investigations conducted in cellular models show that reperfusion of ischemic tissue is associated with a burst of reactive oxidant species within minutes after reperfusion. oxidant injury may play a role in the poor outcome typical of people resuscitated from cardiac arrest. the objective of the present study was to determine the presence and timing of oxidant injury in an in vivo model of cardiac arrest. | 2005 | 16148478 |
| nitrate movement in shallow ground water from swine-lagoon-effluent spray fields managed under current application regulations. | rapid increases in the swine (sus scrofa domestica) population in the 1990s and associated potential for nitrate n pollution of surface waters led the state of north carolina to adopt stringent waste management regulations in 1993. our objectives were to characterize (i) nitrate n movement from waste application fields (wafs) in shallow ground water, and (ii) soil, hydrologic, and biological factors influencing the amount of nitrate n in the adjacent stream. a ground water monitoring study was c ... | 2005 | 16151235 |
| glutathione improves the function of porcine pulmonary grafts stored for twenty-four hours in low-potassium dextran solution. | flush perfusion with low-potassium dextran is the standard strategy in clinical lung preservation. despite improved outcome, endothelial cell injury and surfactant dysfunction remain a significant problem after lung transplantation. the radical scavenger glutathione has been shown to be responsible for the efficacy of celsior solution in lung preservation. we tested the hypothesis that the addition of glutathione to low-potassium dextran might further improve graft function by ameliorating ische ... | 2005 | 16153941 |
| resident-intruder trait aggression is associated with differences in lysine vasopressin and serotonin receptor 1a (5-ht1a) mrna expression in the brain of pre-pubertal female domestic pigs (sus scrofa). | aggressive behaviour exhibited by domestic pigs following encounters with unfamiliar individuals is a serious welfare and economical problem. aggression resulting in skin lesions is similarly prevalent in prepubertal pigs of either sex. little is known about the neural circuits and neuropeptides that control aggression in the pig. because there is evidence for the involvement of the vasopressin and serotonergic systems in the regulation of aggressive behaviour in male mammals, we sought differen ... | 2005 | 16159381 |
| cloning and mapping of the porcine cytochrome-p450 2e1 gene and its association with skatole levels in the domestic pig. | the porcine cytochrome-p450 2e1 (cyp2e1) gene was isolated by screening a pig bac library and partially sequenced. this sequence information was used to identify six single nucleotide polymorphisms (snps) within the cyp2e1 gene and its promoter. in addition, a microsatellite marker tightly linked to the cyp2e1 gene was subcloned from the bac. one of these markers was used to map the cyp2e1 gene distal of swc27 on ssc14, well outside reported quantitative trait loci on ssc14 for skatole, indole a ... | 2005 | 16167985 |
| contribution to comprehension of image formation in confocal microscopy of cornea with rostock cornea module. | to investigate the influence of refractive index of aqueous humour on imaging of corneal endothelium in confocal microscopy. to clarify the phenomenon of dark endothelial and bright epithelial cell membranes in confocal images of corneas. | 2005 | 16170131 |
| intra- and inter-genotypic size variation in the central variable region of the 9rl open reading frame of diverse african swine fever viruses. | african swine fever (asf) viruses are characterised by numerous p72 genotypes, but by low levels of intra-genotypic variation, particularly in domestic pig associated genotypes. as it is precisely these viral lineages that are involved in outbreaks of the disease it is imperative that alternative, more informative gene regions be identified which are suitable for intra-genotypic resolution of relationships. to this end, the central variable region (cvr) of the 9rl open reading frame of diverse a ... | 2005 | 16175341 |
| pimecrolimus permeates less than tacrolimus through normal, inflamed, or corticosteroid-pretreated skin. | the permeabilities of normal human and normal, inflamed, or corticosteroid (cs) pretreated skin of young domestic pigs for pimecrolimus and tacrolimus were compared in vitro, using franz-type diffusion cells. the test articles were either used as 1.0% solutions or as the marketed formulations (elidel 1% cream, protopic 0.1%, and 0.03% ointment). in normal human skin, the permeation rate of pimecrolimus from the 1% cream was about sixfold lower than that of tacrolimus from 0.1% ointment and by a ... | 2005 | 16176283 |
| repair of pig dura in vivo using temperature controlled co(2) laser soldering. | the purpose of this study was to demonstrate that laser soldering might be successfully used for closing holes or cuts in the dura layer, which encapsulates the brain. | 2005 | 16180219 |
| novel calretinin and reelin expressing neuronal population includes cajal-retzius-type cells in the neocortex of adult pigs. | cajal-retzius cells and their secreted product reelin are essential for the lamination of the cerebral cortex. in all species studied to date cajal-retzius cells form a transient neuronal population that almost completely disappears from the neocortex postnatally. recently, in the hippocampal formation of adult domestic pig, we have found a large calretinin- and reelin-immunoreactive cell population that morphologically corresponded to cajal-retzius cells. in the present study, we examined calre ... | 2005 | 16181738 |
| proliferation and apoptosis of spermatogonia in postpuberal boar (sus domesticus) testes with spontaneous unilateral and bilateral abdominal cryptorchidism. | cryptorchidism is a frequent male sexual disorder in mammals, which affects the histology of the tunica propria, interstitial tissue, blood vessels, seminiferous epithelium and testis functioning. in this paper, proliferation and apoptosis were examined in the seminiferous epithelium of both testes from unaffected boars and from boars suffering unilateral and bilateral cryptorchidism. in germ cells, proliferation was studied using the immunohistochemical pcna technique, and apoptosis was analyse ... | 2005 | 16185749 |
| superficial contact cryoablation attenuates experimentally created lung air leakage. | previously, we, and others found that cryoablation on normal lung produced localized pulmonary hemorrhage and edema, causing obliteration of air space. therefore, we hypothesized that lung air leakage may be diminished by this procedure. in the present study, we examined if cryoablation can attenuate experimentally created lung air leakage. male domestic pigs (n=4) underwent a thoracotomy. the lung was resected approximately 5 mm in diameter and 1mm in depth to create air leakage lesions. an arg ... | 2005 | 16202403 |
| gut luminal microdialysis of glycerol as a marker of intestinal ischemic injury and recovery. | to evaluate microdialysis as a method to assess different degrees of intestinal damage and recovery during ischemia and reperfusion; to evaluate information obtained from microdialysis catheters in the peritoneum, the gut wall, and the gut lumen. | 2005 | 16215382 |
| the cd11a partner in sus scrofa lymphocyte function-associated antigen-1 (lfa-1): mrna cloning, structure analysis and comparison with mammalian homologues. | lymphocyte function-associated antigen-1 (lfa-1, cd11a/cd18, alphalbeta2), the most abundant and widely expressed beta2-integrin, is required for many cellular adhesive interactions during the immune response. many studies have shown that lfa-1 is centrally involved in the pathogenesis of several diseases caused by repeats-in-toxin (rtx)-producing bacteria. | 2005 | 16216120 |
| distribution of porcine endogenous retroviruses (pervs) dna in organs of a domestic pig. | domestic pig may serve as the most appropriate organ source for human xenotransplantation in the future. however, there is a serious threat of xenogeneic pathogens transmission, especially porcine endogenous retroviruses (pervs) which are present in genomes of all pigs. the aim of this study was to monitor the prevalence and distribution of perv dna in organs of a domestic pig. | 2005 | 16218033 |
| [proposal for changing the spot checking examination regarding the control of the maintenance of freedom from aujeszky's disease (ad)]. | in germany the last outbreak of aujeszky's disease (ad) in a holding of domestic pigs had been officially confirmed in the year 2000, and, since february 2003 germany is officially confirmed free of ad. since this time the ad free status is monitored according to chapter ii of the annex of the regulation for the protection against aujeszky's disease. as an alternative monitoring protocol two variants of a two step random sampling scheme is proposed which reduces the sample size from a complete i ... | 2005 | 16218180 |
| a novel spleen-preserving laparoscopic technique using radiofrequency ablation in a porcine model. | partial splenectomy is considered to be the optimal management for a variety of diseases. at the same time, laparoscopic procedures are increasingly used because they present certain advantages against their open counterparts. in this study, the safety and efficacy of radiofrequency ablation (rfa) were evaluated in laparoscopic partial splenectomy performed in a pig model. | 2005 | 16228858 |
| plasma disappearance of indocyanine green: a marker for excretory liver function? | to investigate whether the plasma disappearance rate of indocyanine green (icg) assessed using a commercially available bedside monitor provides an accurate estimation of cumulative biliary icg excretion in a clinically relevant model of long-term, hyperdynamic porcine endotoxemia. | 2005 | 16231068 |
| effects of spontaneous breathing during airway pressure release ventilation on respiratory work and muscle blood flow in experimental lung injury. | to evaluate the effects of spontaneous breathing at ambient airway pressure (paw) and during airway pressure release ventilation (aprv) on respiratory work and respiratory muscle blood flow (rmbf) in experimental lung injury. | 2005 | 16236977 |
| an epidural cooling catheter protects the spinal cord against ischemic injury in pigs. | using swine, we investigated whether epidural placement of a cooling catheter rather than infusing iced saline solution could protect the spinal cord from ischemia during aortic surgery. | 2005 | 16242463 |
| bone regeneration in osseous defects using a resorbable nanoparticular hydroxyapatite. | this animal study examined the de novo bone formation in bony defects following the insertion of autogenous bone alone versus an injectable nanoparticle hydroxyapatite alone and in combination with 25% autogenous bone. the regenerative potentials of the tested materials were compared with each other. | 2005 | 16243180 |
| management of wild ungulate populations in italy: captive-breeding, hybridisation and genetic consequences of translocations. | captive-reproduced stocks of some species of ungulates (artiodactyla), and particularly the red deer (cervus elaphus), fallow deer (dama dama), roe deer (capreolus capreolus) and the wildboar (sus scrofa) are more or less extensively translocated in italy, mainly for local reintroductions or restocking of exploited wild populations. however, captive breeding often involves the reproduction of non-indigenous individuals or the production of artificial hybrids. consequently, translocations of capt ... | 2005 | 16244928 |
| comparison of a commercial elisa with the modified agglutination test for detection of toxoplasma infection in the domestic pig. | the modified agglutination test (mat) and a commercially available enzyme-linked immunosorbent assay (elisa) were compared for detection of antibodies to toxoplasma gondii in naturally-infected market-aged pigs. infected pigs were obtained from commercial slaughter facilities and from farms where infection had previously been detected. infection was confirmed by bioassay in cats. for 70 bioassay positive pigs, 60 were positive by mat (85.7% sensitivity) and 62 were positive by elisa (88.6% sensi ... | 2005 | 15740853 |
| ascariasis is a zoonosis in denmark. | a preliminary epidemiological survey indicated an association between ascaris infections in danish patients and contact with pigs or pig manure. in the present study, we compared ascaris worms collected from humans and ascaris worms collected from pigs by amplified fragment length polymorphism (aflp) analysis, a technique for whole-genome fingerprinting, and by pcr-linked restricted fragment length polymorphism (pcr-rflp) analysis of the internal transcribed spacer region of nuclear rdna. the af ... | 2005 | 15750075 |
| smooth muscle cell proliferation index correlates with 111in-labeled antibody z2d3 uptake in a transplant vasculopathy swine model. | transplant vasculopathy is a major cause of morbidity and mortality in heart transplantation. the proliferation of coronary vascular smooth muscle cells is a hallmark of transplant vasculopathy. the goal of this study was to detect coronary vascular smooth muscle cell proliferation in a swine model by imaging regions of uptake of a monoclonal antibody (z2d3) labeled with 111in. | 2005 | 15750167 |
| comparison between dobutamine and levosimendan for management of postresuscitation myocardial dysfunction. | to investigate the effects of levosimendan, a nonadrenergic inotropic calcium sensitizer, in comparison with adrenergic dobutamine for the management of postresuscitation myocardial dysfunction following resuscitation from prolonged cardiac arrest. | 2005 | 15753736 |
| worldwide phylogeography of wild boar reveals multiple centers of pig domestication. | mitochondrial dna (mtdna) sequences from 686 wild and domestic pig specimens place the origin of wild boar in island southeast asia (isea), where they dispersed across eurasia. previous morphological and genetic evidence suggested pig domestication took place in a limited number of locations (principally the near east and far east). in contrast, new genetic data reveal multiple centers of domestication across eurasia and that european, rather than near eastern, wild boar are the principal source ... | 2005 | 15761152 |
| comparison of external catheters with subcutaneous vascular access ports for chronic vascular access in a porcine model. | we sought to compare the outcomes of two chronic vascular access techniques, the externalized catheter and the subcutaneous vascular access port, in pigs. female farm pigs (n = 30) underwent placement of a chronic vascular access device in the jugular vein for a research protocol: 18 of the animals underwent placement of a tunneled hickman catheter (thc), and the remaining 12 animals underwent placement of a subcutaneous vascular access port (vap) without external components. after placement of ... | 2005 | 15773772 |
| elephants and human color-blind deuteranopes have identical sets of visual pigments. | being the largest land mammals, elephants have very few natural enemies and are active during both day and night. compared with those of diurnal and nocturnal animals, the eyes of elephants and other arrhythmic species, such as many ungulates and large carnivores, must function in both the bright light of day and dim light of night. despite their fundamental importance, the roles of photosensitive molecules, visual pigments, in arrhythmic vision are not well understood. here we report that eleph ... | 2005 | 15781694 |
| anatomical study on true hermaphroditism in an indian pig (sus scrofa domesticus). | a pig was confirmed to be a true hermaphrodite on the basis of gross and histomorphological studies of the genital organs. the genitalia was consisted of left ovary, oviduct, two coiled uterine horns, body of uterus along with right testis and an epididymis. vagina and vulva were absent but male urethra with prostate gland was present. grossly the size of all the genital organs appeared to be normal. histomorphologically, testis and epididymis were underdeveloped as there was no clearcut spermat ... | 2005 | 15785130 |
| the new selective i(ks)-blocking agent hmr 1556 restores sinus rhythm and prevents heart failure in pigs with persistent atrial fibrillation. | antiarrhythmic drugs for treatment of atrial fibrillation in patients with heart failure are limited by proarrhythmia and low efficacy. experimental studies indicate that the pure i(ks) blocking agents chromanol 293b and hmr 1556 prolong repolarization more markedly at fast than at slow heart rates and during beta-adrenergic stimulation. these properties may overcome some of the above quoted limitations. | 2005 | 15795798 |
| impact of a double-pigtail stent on ureteral peristalsis in the porcine model: initial studies using a novel implantable magnetic sensor. | the effect of stents on ureteral peristalsis in vivo is not entirely clear. we sought to develop a minimally invasive method for its study. | 2005 | 15798413 |
| laparoscopic ureterocalicostomy: development of a technique simplified by application of nitinol clips and a wet monopolar electrosurgery device. | we developed a technique for laparoscopic ureterocalicostomy with the use of intracorporeal suturing and subsequently simplified the technique by application of experimental nitinol clips. | 2005 | 15798423 |
| adrenergic stimulation of rb+ uptake in pig hearts in vivo assessed by 87rb mrs. | it was previously shown that the adrenergic agonist dobutamine stimulates rb(+) uptake in isolated pig hearts. in the present work we examined whether dobutamine can increase rb(+) uptake rate in vivo. open-chest domestic pigs (n = 14) were used under general anesthesia. the surface coil was placed against the anterior left ventricular wall to obtain (87)rb spectra using a spectrometer interfaced with the 7t, 30-cm horizontal bore magnet. rbcl was infused at the rate of 1.35 +/- 0.14 mmol/kg/hr ... | 2005 | 15799046 |
| polyclonal hypergammaglobulinemia and formation of hydrophobic immune complexes in porcine reproductive and respiratory syndrome virus-infected and uninfected pigs. | infection of young conventional, domestic pigs with porcine reproductive and respiratory syndrome virus (prrsv) strains vr2332 and ja142 resulted in a rapid, progressive increase in serum igg reaching maximum levels of 20-30 mg/ml at about 3 weeks post infection (p.i.), which were maintained until at least 63 days p.i., whereas the level of serum igg remained at 4-6 mg/ml in sham infected pigs. in most of the vr2332 and ja142-infected pigs hypergammaglobulimenia was associated with the formation ... | 2005 | 15802958 |
| nerve monitoring and stimulation during endoscopic neck surgery in the pig. | to determine the feasibility of recurrent laryngeal nerve monitoring and stimulation during endoscopic neck surgery in an animal model. | 2005 | 15805886 |
| hepatic function in hypothermically stored porcine livers: comparison of hypothermic machine perfusion vs cold storage. | hypothermic machine perfusion (hmp) has a potential to relieve the current donor liver crisis by providing an improved and extended preservation method. this study examined the effect of hmp on hepatocellular functions, using a prototype liver transporter capable of preserving livers for 24 hours. livers obtained from adult farm pigs (28 to 32 kg body weight) were divided into three groups: fresh control, hmp, and simple cold storage (n = 4 each). a 4-hour normothermic reperfusion of livers was ... | 2005 | 15808637 |
| the effect of age on the morphometric sperm traits of domestic pigs (sus scrofa domestica). | the experiment was conducted using 20 male domestic pigs, which were in 2 (equal-sized) age groups: under 14 months old and over 18 months old. at least 5 ejaculates from each male were taken, and in each ejaculate, morphometric measurements of 50 spermatozoa were made. the measured parameters were head area, head length and width, and flagellum length. for each ejaculate, the basic physical traits and the frequency of occurrence of developmental anomalies of the spermatozoa were examined. it wa ... | 2005 | 15809675 |
| successional behavior and occurrence matrix of carrion-associated arthropods in the urban area of medellín, colombia. | forensic entomology is a scientific tool applied to the study of insect or arthropod succession at the scene of a crime or that associated with an accident or natural death. interpreting this succession provides information to determine minimum and maximum limits of the postmortem interval (pmi), that is, the time between death and the discovery of the body. this study was carried out during the rainy season, from 27 october to 12 december 2002 in an urban area of the city of medellín, colombia. ... | 2005 | 15813558 |
| experimental hypercholesterolemia differentially affects adventitial vasa vasorum and vessel structure of the left internal thoracic and coronary arteries. | atherosclerosis is a chronic and diffuse disease that affects all vascular beds. however, some vascular beds are more prone to atherosclerosis than others. recent evidence suggests a role for the vasa vasorum in the atherosclerotic process. we hypothesized that there is a difference in adventitial vasa vasorum structure between the left internal thoracic artery and the coronary artery. hence the current study was designed to characterize and compare the structure of the adventitial vasa vasorum ... | 2005 | 15821642 |
| chromosome restriction enzyme digestion in domestic pig (sus scrofa) constitutive heterochromatin arrangement. | the bimodal karyotype of pig appears to contain two types of constitutive heterochromatin, reflecting different satellite dna families: gc-rich heterochromatin located mainly in the centromeric regions of the biarmed chromosomes, and less-gc-rich heterochromatin in the centromeric regions of the one-armed chromosomes. in order to better discriminate this constitutive heterochromatin, we treated pig chromosome preparations with eight different restriction endonucleases, followed by c-banding. thi ... | 2005 | 15824456 |
| increases in both buccal and sublingual partial pressure of carbon dioxide reflect decreases of tissue blood flows in a porcine model during hemorrhagic shock. | earlier studies had demonstrated that gastric partial pressure of carbon dioxide (pco2) of the gastric wall is an early indication of perfusion failure. because hypercarbia is a general phenomenon of perfusion failure, this study investigated whether sublingual and buccal mucosal tissue pco2 also serve as a sensitive indicator of systemic blood flow during hemorrhagic shock. | 2005 | 15824661 |
| optimization of a blood pool contrast agent injection protocol for mr angiography. | to design an ideal first-pass profile for mr angiography (mra) by optimizing a multiphasic injection protocol based on two experimental animal models. | 2005 | 15834909 |
| phylogenetic analysis of classical swine fever virus (csfv) field isolates from outbreaks in south and central america. | to date, there is little information concerning the epidemiological situation of classical swine fever (csf) in the americas. besides summarizing the available data, genotyping of isolates from outbreaks in domestic pigs in several countries of south and central america was performed. for this, a 190 base fragment of the e2 envelope glycoprotein gene was used. european strains and isolates, and historical isolates from the united states (us) were included for comparison. in contrast to the situa ... | 2005 | 15845261 |
| expression of bone matrix proteins during de novo bone formation using a bovine collagen and platelet-rich plasma (prp)--an immunohistochemical analysis. | this animal study (domestic pig) examined the bone formation after filling defined defects with autogenous bone or a collagen lyophilisat in combination with platelet-rich-plasma (prp) by evaluating bone matrix proteins. six groups, both materials with and without prp in two concentrations (+ 1, + 2) were compared to untreated bone by means of immunohistochemistry at 2, 4, 12 and 26 weeks. bmp-2 expression was increased at 2 weeks in the collagen + 1 group and after 4 weeks in the collagen + 1 a ... | 2005 | 15585260 |
| long-term monitoring of classical swine fever in wild boar (sus scrofa sp.) using serological data. | in the european community, epizootics of classical swine fever (csf) in the wild boar (sus scrofa) are compulsorily monitored because transmission may occur between wild boars and domestic pigs, causing heavy economic losses to the pork industry. the estimation of incidence in populations of wild boars is generally based on viroprevalence. however, viral isolation becomes rare when the incidence is low because the virus cannot be detected for more than a few weeks following infection. on the con ... | 2005 | 15610721 |
| degenerative changes of porcine intervertebral disc induced by vertebral endplate injuries. | graded endplate injuries were performed in porcine lumbar discs. the effects of such injuries were compared to control animals in which a sham operation was performed. | 2005 | 15644752 |
| il-1beta in bronchial lavage fluid is a non-invasive marker that predicts the viability of the pulmonary graft from the non-heart-beating donor. | viability testing of the pulmonary graft retrieved from the non-heart-beating donor (nhbd) is mandatory for successful outcome after lung transplantation. functional assessment by ex vivo reperfusion, however, remains a cumbersome procedure. in this study, therefore, we wanted to investigate the possible value of the proinflammatory cytokines interleukin-1beta (il-1beta) and tumor necrosis factor-alpha (tnf-alpha) measured in bronchial lavage fluid (blf) in predicting functional outcome of the p ... | 2005 | 15653374 |
| volumetric cine imaging for cardiovascular circulation using prototype 256-detector row computed tomography scanner (4-dimensional computed tomography): a preliminary study with a porcine model. | this is a preliminary demonstration of volumetric cine imaging of cardiovascular circulation in domestic pigs using a prototype 256-detector row computed tomography (ct) scanner. the scan range is approximately 120 mm in the craniocaudal direction, with a 0.5-mm slice thickness. the thin sections can be used to create cine loops in multiple planes. thus, the 256-detector row ct scanner overcomes some of the limitations of present helical ct methods. | 2005 | 15665678 |
| comparison of erbium:yttrium-aluminum-garnet and holmium:yttrium-aluminum-garnet lasers for incision of urethra and bladder neck in an in vivo porcine model. | to evaluate, in an animal model, differences in wound healing and scar formation in healthy urethra and bladder neck incised with the erbium (er):yttrium-aluminum-garnet (yag) and holmium (ho):yag lasers. | 2005 | 15667902 |
| the phylogeny of chinese indigenous pig breeds inferred from microsatellite markers. | a genetic study of 32 local chinese, three foreign pig breeds [duroc (du), landrace and yorkshire], and two types of wild boar (hainan and dongbei wild boar) based on 34 microsatellite loci was carried out to clarify the phylogeny of chinese indigenous pig breeds. the allele frequencies, effective numbers of alleles, and the average heterozygosity within populations were calculated. the results showed that the genetic variability of the lingao pig was the largest, while the jiaxing pig was the l ... | 2005 | 15670125 |
| comparative analysis of protein coding sequences from human, mouse and the domesticated pig. | the availability of abundant sequence data from key model organisms has made large scale studies of molecular evolution an exciting possibility. here we use full length cdna alignments comprising more than 700,000 nucleotides from human, mouse, pig and the japanese pufferfish fugu rubrices in order to investigate 1) the relationships between three major lineages of mammals: rodents, artiodactyls and primates, and 2) the rate of evolution and the occurrence of positive darwinian selection using c ... | 2005 | 15679890 |
| seroprevalence of noroviruses in swine. | noroviruses (nvs) are important human pathogens that cause acute gastroenteritis. genetically related animal enteric nvs have also been described, but there is no evidence of interspecies transmission of nvs. in this study we characterized antibody prevalence among domestic pigs by using recombinant capsid antigens of two human nvs (norwalk and hawaii) and one swine nv (sw918) that is genetically related to gii human nvs. recombinant sw918 capsid protein expressed in baculovirus self-assembled i ... | 2005 | 15695660 |
| transscleral implantation and neurophysiological testing of subretinal polyimide film electrodes in the domestic pig in visual prosthesis development. | loss of photoreceptor function is responsible for a variety of blinding diseases, including retinitis pigmentosa. advances in microtechnology have led to the development of electronic visual prostheses which are currently under investigation for the treatment of human blindness. the design of a subretinal prosthesis requires that the stimulation device should be implantable in the subretinal space of the eye. current limitations in eye surgery have to be overcome to demonstrate the feasibility o ... | 2005 | 15876656 |
| comparison of male and female meiotic segregation patterns in translocation heterozygotes: a case study in an animal model (sus scrofa domestica l.). | the comparison of male and female meiotic segregation patterns for individuals carrying identical reciprocal translocations has been rarely reported in mammalian species. the main comparative study involving males and females with comparable genetic background has been performed in the mouse. swine is another relevant animal model species for meiotic studies. here we present the segregation patterns determined for sows carrying one of the two following reciprocal translocations: 38, xx, rcp(3;15 ... | 2005 | 15878917 |
| a dna vaccine expressing the e2 protein of classical swine fever virus elicits t cell responses that can prime for rapid antibody production and confer total protection upon viral challenge. | immunization of domestic pigs with a dna vaccine expressing the complete e2 protein of classical swine fever virus (csfv) conferred total protection against a severe viral challenge. immunization with three doses of plasmid pcdna3.1/e2 elicited a consistent and specific, mhc class ii restricted t cell response in the three domestic pigs analyzed, in the absence of detectable anti-csfv antibodies in serum. upon challenge specific t cell responses were boosted in the three vaccinated pigs, and a r ... | 2005 | 15882536 |
| management strategy impacts on ammonia volatilization from swine manure. | ammonia emitted from manure can have detrimental effects on health, environmental quality, and fertilizer value. the objective of this study was to measure the potential for reduction in ammonia volatilization from swine (sus scrofa domestica) manure by temperature control, stirring, addition of nitrogen binder (mohave yucca, yucca schidigera roezl ex ortgies) or urease inhibitor [n-(n-butyl) thiophosphoric triamide (nbpt)], segregation of urine from feces, and ph modification. swine manure [tot ... | 2005 | 15888898 |
| stent-based delivery of abt-578 via a phosphorylcholine surface coating reduces neointimal formation in the porcine coronary model. | stent-based delivery of the antiproliferative and immunosuppressive macrocyclic lactone sirolimus reduces neointimal formation and restenosis by cytostatic inhibition of vascular smooth muscle cell proliferation. the objective of this study was to determine the feasibility and efficacy of stent-based delivery of abt-578, a structurally unique macrocyclic lactone. stainless steel balloon-expandable stents were coated with thin layer of phosphorylcholine (pc) or pc with abt-578 (10 microg/mm). fif ... | 2005 | 15900559 |
| [the development of the gene pool in the microevolution of sus scrofa and the role of heterozygosity in the breed-forming process]. | the gene pool formation of the modem domestic breeds of pig sus scrofa domestica and their genesis based on hybridization of wild ancestral forms of the european and asian origin were studied using molecular immunogenetic methods. males of the european and central asian s. scrofa subspecies (s. s. scrofa and s. s. nigripes were hybridized with domestic pigs of the swedish landrace and vietnamese black masked breeds. in addition, we examined the genotypic structure of 65 wild, aboriginal, and loc ... | 2005 | 15909917 |
| correlation between positivity for immunoglobulin a antibodies and viraemia of swine hepatitis e virus observed among farm pigs in japan. | to evaluate the usefulness of detection of antibodies to hepatitis e virus (hev) to screen for viraemic pigs, serum samples obtained from 1425 1-6-month-old pigs in japan were tested for swine hev rna and igg, igm and iga classes of anti-hev antibody. fifty-five (5 %) of the 1071 2-5-month-old pigs were positive for swine hev rna, but none of 218 1-month-old pigs or 136 6-month-old pigs had detectable hev rna. the prevalence of anti-hev igg among the viraemic pigs (67 %, 37/55) was similar to th ... | 2005 | 15914860 |
| macro anatomical investigations of the cranial cervical ganglion in domestic pig (sus scrofa domesticus). | in this study, the left and right cranial cervical ganglia (ganglion cervicale craniale) of eight young (four male, four female) domestic pigs weighing around 70-80 kg were inspected macro anatomically. the cranial cervical ganglion (ccg) was found cranio-ventrally of the distal ganglion of the vagus nerve, medial of the jugular process extremity, ventral of the atlas, dorsal of the epiglottis base and medial of the common root (cr) established by the internal carotid and occipital arteries. the ... | 2005 | 15929737 |
| a report of decomposition rates of a special burial type in edmonton, alberta from an experimental field study. | regional studies that examine decomposition rates of certain faunal remains can help to determine time since death. forensic anthropologists have long used qualitative decomposition data, but linking these to more quantitative data could improve time since death estimations. experiments were developed in which domestic pigs (sus scrofa) were buried with varying characteristics then excavated and observed over a period of 15 months in edmonton, alberta. data recorded after two weeks, five weeks, ... | 2005 | 15932100 |
| influence of ventricular pacing on myocardial oxygen tension. | the influence of heart rate on cardiac output, oxygen consumption, and myocardial activity has been widely investigated. however, the influence of heart rate on myocardial oxygen tension (po2) remains unclear. since the introduction of flexible po2 micro catheters to measure partial oxygen tension in a working muscle, it is possible to investigate the influence of heart rate on myocardial oxygen tension. | 2005 | 15939441 |
| evaluation of a barrier cream against the chemical warfare agent vx using the domestic white pig. | the purpose of this study was to evaluate the efficacy of a novel barrier cream formulation at reducing the percutaneous toxicity of a 2xld(50) liquid challenge of nerve agent (vx). the study was conducted in vitro and in vivo using the domestic pig. pretreatment of the (inner ear skin) exposure site with barrier cream eliminated mortality, reduced cholinesterase inhibition and prevented any physiological or biochemical signs of intoxication. in contrast, untreated animals exposed to vx exhibite ... | 2005 | 15943757 |
| retrograde renal cooling during radio frequency ablation to protect from renal collecting system injury. | we evaluated the protective effect of continuous retrograde irrigation of ice-cold saline on the renal collecting system during central parenchymal temperature based radio frequency ablation (rfa). | 2005 | 15947688 |
| inducible nitric oxide synthase inhibition improves intestinal microcirculatory oxygenation and co2 balance during endotoxemia in pigs. | we examined whether selective inhibition of inducible nitric oxide synthase (inos) promotes intestinal microvascular oxygenation (micropo2) and co2 off-load after endotoxic shock. | 2005 | 15959764 |
| the occurrence of encephalomyocarditis virus (emcv) in european pigs from 1990 to 2001. | the occurrence of encephalomyocarditis virus (emcv) among domestic pigs and wild boar in several european countries is described and discussed. from 1990 to 2001 clinical outbreaks were analysed and serum samples, partly from existing screening programmes, were tested for antibodies against emcv. most clinical emcv outbreaks were reported in belgium (320), followed by italy (110), greece (15) and cyprus (6). the outbreaks appeared to be clustered in 'endemic areas' with an increase in outbreaks ... | 2005 | 15962562 |
| effects of antemortem ingestion of ethanol on insect successional patterns and development of phormia regina (diptera: calliphoridae). | the effects of antemortem ingestion of ethanol by domestic pigs, sus scrofa l., on postmortem insect successional patterns and the development of phormia regina (meigen) were studied during summer 2003 in blacksburg, va. insect samples were collected from the carcasses of ethanol-treated and untreated pigs for 10 d postmortem during two successional studies. in total, 32 insect taxa were collected during the two studies, with 29 and 27 taxa observed on the carcasses of ethanol-treated and untrea ... | 2005 | 15962802 |
| trichinella britovi etiological agent of sylvatic trichinellosis in the republic of guinea (west africa) and a re-evaluation of geographical distribution for encapsulated species in africa. | in west africa, trichinella infection was documented in humans and animals from senegal in the 1960s, and the biological characters of one isolate showed a lower infectivity to domestic pigs and rodents when compared with that of a trichinella spiralis pig isolate from europe. to identify the trichinella species present in west africa, a survey was conducted in a total of 160 wild animals in the republic of guinea. three viverridae, one true civet (viverra civetta) and two african palm civets (n ... | 2005 | 15964575 |
| [high-resolution t1-weighted mr-lymphography of inguinal lymph nodes after interstitial application of gadomer-17 in animal experiments]. | to evaluate the microstructural anatomy of inguinal lymph nodes in pigs after interstitial mr-lymphography with the dendritic contrast agent gadomer-17. | 2005 | 15973599 |
| hepatic hemorrhage caused by percutaneous tumor ablation: radiofrequency ablation versus cryoablation in a porcine model. | to determine the extent of hepatic hemorrhage caused by percutaneous cryoablation performed with a small-diameter cryoablation probe compared with that caused by percutaneous radiofrequency (rf) ablation in a porcine model. | 2005 | 15987968 |
| hand-assisted laparoscopic partial nephrectomy in the porcine model using gelatin matrix hemostatic sealant without hilar occlusion. | gelatin matrix hemostatic sealant (gmhs) has been used for hemostasis during partial nephrectomy with hilar clamping. the objective of this study was to determine the ability of gmhs to achieve hemostasis without hilar clamping in the porcine model. | 2005 | 15989447 |
| trichinae certification in the united states pork industry. | control of trichinella infection in u.s. pork has traditionally been accomplished by inspection of individual carcasses at slaughter or by post-slaughter processing to inactivate parasites. we propose that an alternative to individual carcass testing or processing can be used when pigs are raised in production systems where risk of exposure to trichinella spiralis has been mitigated. declines in prevalence of this parasite in u.s. domestic swine during the last 30 years, coupled with improvement ... | 2005 | 15993000 |
| developmental competence of somatic cell nuclear transfer embryos reconstructed from oocytes matured in vitro with follicle shells in miniature pig. | the developmental competence of domestic pig oocytes that were transferred to somatic cell nuclei of miniature pig was examined. a co-culture system of oocytes with follicle shells was used for the maturation of domestic pig oocytes in vitro. co-cultured oocytes progressed to the metaphase ii stage of meiosis more quickly and more synchronously than non co-cultured oocytes. oocytes were enucleated and fused with fibroblast cells of potbelly miniature pig at 48 h of maturation. the blastocyst for ... | 2005 | 15996114 |
| genetic profile and serosurvey for virus infections of japanese wild boars in shikoku island. | to estimate the genetic background of japanese wild boars inhibiting the 4 prefectures of shikoku island (kagawa, tokushima, kouchi and ehime), we examined haplotypes of mitochondrial dna (mtdna) and genotypes of the nuclear glucosephosphate isomerase-processed pseudogene (gpip) in 189 wild boars. of the 8 different mtdna haplotypes (j5, j10, j12, j13, j15, j19, j20 and e33) detected in shikoku island, the first to be identified were j19 and j20 (of japanese wild boar lineage) and e33 (of europe ... | 2005 | 15997182 |
| comparative study of tacrolimus and paclitaxel stent coating in the porcine coronary model. | tacrolimus is a potent antiproliferative and immunosuppressive agent allowing for improved endothelial regeneration. the aim of our study was the preclinical evaluation of tacrolimus in a drug eluting nonerodable polymer stent system and its comparison with paclitaxel. | 2005 | 15997345 |
| divergence time of porcine reproductive and respiratory syndrome virus subtypes. | porcine reproductive and respiratory syndrome virus (prrsv) recently emerged in domestic pigs of western europe and north america. although time of emergence was identical on the two continents, genetic composition was markedly different with a clear geographical subtype structure, indicating that subtypes diverged in separate reservoirs prior to emergence. genetic analyses have shown that the most recent common ancestor (mrca) of western european isolates existed around 1980 and that these orig ... | 2005 | 16000650 |
| domesticated pigs in eastern indonesia. | 2005 | 16020714 | |
| vaginal contraceptive activity of a chelated vanadocene. | bis(cyclopentadienyl) complexes of vanadium (iv) or vanadocenes are rapid and potent inhibitors of human sperm motility with potential as a new class of contraceptive agents. this study sought to determine the vaginal contraceptive activity of vanadocene dithiocarbamate (vddtc), a stable vanadocene (iv)-chelated complex, using the standard rabbit model as well as the domestic pig as a physiologically relevant animal model for contraception. in experiment i, ovulating new zealand white does in su ... | 2005 | 16022855 |
| comparative genetic characterization of porcine circovirus type 2 samples from german wild boar populations. | pcv-2 is involved in "postweaning multisystemic wasting syndrome" (pmws), "porcine dermatitis and nephropathy syndrome" (pdns), respiratory and reproductive disorders, and thereby plays a crucial role in today's swine production world-wide. the virus is apparently ubiquitous in domestic pigs and has also been demonstrated in wild pigs. up to now, a characterization of pcv-2 samples from wild pigs, which might help to estimate the possible role of wild pigs as sources of domestic pig infection, h ... | 2005 | 16023798 |
| a study of the potential of the pig as a model for the vaginal irritancy of benzalkonium chloride in comparison to the nonirritant microbicide phi-443 and the spermicide vanadocene dithiocarbamate. | a porcine model was established to test the mucosal toxicity potential of a thiophene thiourea (phi-443)-based anti-hiv microbicide and a vanadocene-based spermicide, vanadocene dithiocarbamate (vddtc) in comparison to benzalkonium chloride (bzk). nine domestic pigs (duroc) in nonestrus stage received a single intravaginal application of 2% bzk, 2% phi-443, or 0.1% vddtc-containing gel. at various times after gel application, cell differentials and levels of inflammatory cytokines (il-1beta, il- ... | 2005 | 16036864 |