Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| molecular identification of ctx-m and blaoxy/k1 beta-lactamase genes in enterobacteriaceae by sequencing of universal m13-sequence tagged pcr-amplicons. | plasmid encoded blactx-m enzymes represent an important sub-group of class a beta-lactamases causing the esbl phenotype which is increasingly found in enterobacteriaceae including klebsiella spp. molecular typing of clinical esbl-isolates has become more and more important for prevention of the dissemination of esbl-producers among nosocomial environment. | 2009 | 19161622 |
| tigecycline in combination with other antimicrobials: a review of in vitro, animal and case report studies. | tigecycline has been investigated in combination with other antibacterials against a wide range of susceptible and multiresistant gram-positive and gram-negative bacteria. combinations have been analysed in vitro, in animal models and in human case reports. in vitro, tigecycline combined with other antimicrobials produces primarily an indifferent response (neither synergy nor antagonism). nevertheless, synergy occurred when tigecycline was combined with rifampicin against 64-100% of enterococcus ... | 2009 | 19162449 |
| occurrence of efflux mechanism and cephalosporinase variant in a population of enterobacter aerogenes and klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases. | we investigated the occurrence of multidrug resistance in 44 enterobacter aerogenes and klebsiella pneumoniae clinical isolates. efflux was involved in resistance in e. aerogenes isolates more frequently than in k. pneumoniae isolates (100 versus 38% of isolates) and was associated with the expression of phenylalanine arginine beta-naphthylamide-susceptible active efflux. acra-tolc overproduction in e. aerogenes isolates was noted. an analysis of four e. aerogenes isolates for which cefepime mic ... | 2009 | 19164140 |
| two clinical strains of klebsiella pneumoniae carrying plasmid-borne blaimp-4, blashv-12, and arma isolated at a pediatric center in shanghai, china. | two cases of pulmonary infection due to strains of multidrug-resistant klebsiella pneumoniae were investigated. beta-lactamase determinants, such as bla(imp-4) and bla(shv-12), and the 16s rrna methyltransferase-encoding gene arma were detected in these plasmid-bearing organisms. the integron-borne bla(imp-4) and arma contained intervening sequences highly related to those of a vibrio cholerae o139 plasmid found in hangzhou, china. | 2009 | 19164142 |
| intranasal porous polyethylene implant extrusion 7 years after insertion in a patient with hashimoto disease. | we report a case of intranasal porous polyethylene implant extrusion 7 years after insertion in a patient with hashimoto disease. we also discuss the possible causes of the extrusion and convey the histopathologic examination and microbiological investigation results of the samples taken from the removed implant. | 2009 | 19164994 |
| changes in bacterial isolates from burn wounds and their antibiograms: a 20-year study (1986-2005). | our aim is to elucidate shifts in the bacterial spectrum colonising burn wounds and corresponding antibiotic susceptibilities during a 20-year study period. | 2009 | 19167827 |
| blood culture confirmed bacterial sepsis in neonates in a north indian tertiary care center: changes over the last decade. | the spectrum of organisms causing sepsis is different in developing countries. data on the recent trends of organisms causing sepsis are limited. this study was conducted in a tertiary care neonatal unit in northern india. all inborn babies with blood-culture-positive sepsis from 1995 to 2006 were divided into two epochs, viz. 1995 to 1998 (epoch i) and 2001 to 2006 (epoch ii). organisms were grouped into early (<72 h) and late onset (> or =72 h) sepsis groups. the overall incidence of sepsis, t ... | 2009 | 19168958 |
| shv-28, an extended-spectrum beta-lactamase produced by a clinical isolate of klebsiella pneumoniae in south india. | shv-28, an extended spectrum beta-lactamase from a clinical isolate of klebsiella pneumoniae , had an isoelectric point of 7.6 and a substrate profile showing preferential hydrolysis for cefotaxime over ceftazidime. it differed from shv-1 by one amino acid substitution. the conserved s-t-f-k and k-t-g motifs were identified by shv-28 protein sequencing. | 2009 | 19172061 |
| role of bacterial adhesion in the microbial ecology of biofilms in cooling tower systems. | the fate of the three heterotrophic biofilm forming bacteria, pseudomonas aeruginosa, klebsiella pneumoniae and flavobacterium sp. in pilot scale cooling towers was evaluated both by observing the persistence of each species in the recirculating water and the formation of biofilms on steel coupons placed in each cooling tower water reservoir. two different cooling tower experiments were performed: a short-term study (6 days) to observe the initial bacterial colonization of the cooling tower, and ... | 2009 | 19177226 |
| synthesis, cytotoxic and antimicrobial screening of a proline-rich cyclopolypeptide. | present study describes the first total synthesis of a cyclic heptapeptide, stylisin 1 (8) via coupling of tetrapeptide boc-l-tyrosinyl-l-prolyl-l-leucyl-l-proline-oh and tripeptide l-phenylalanyl-l-isoleucyl-l-proline-ome followed by cyclization of linear heptapeptide segment. structure elucidation of synthesized cyclopeptide was done on basis of detailed spectral as well as elemental analysis. from the results of pharmacological screening, it was concluded that cyclopeptide 8 possessed moderat ... | 2009 | 19182416 |
| novel e. coli beta-ketoacyl-acyl carrier protein synthase iii inhibitors as targeted antibiotics. | beta-ketoacyl-acyl carrier protein synthase (kas) iii is a condensing enzyme that initiates fatty acid biosynthesis in most bacteria. we determined three pharmacophore maps from receptor-oriented pharmacophore-based in silico screening of the x-ray structure of escherichia coli kas iii (eckas iii) and choose 16 compounds as candidate eckas iii inhibitors. binding inhibitors were characterized using saturation-transfer difference nmr spectroscopy (std-nmr), and binding constants were determined w ... | 2009 | 19185501 |
| diversity of hydrocarbon-degrading klebsiella strains isolated from hydrocarbon-contaminated estuaries. | to investigate the diversity and the catabolic capacity of oil-degrading klebsiella strains isolated from hydrocarbon-contaminated sediments in santos-são vicente estuary systems in brazil. | 2009 | 19187158 |
| the antimicrobial activity of four commercial essential oils in combination with conventional antimicrobials. | due to the emergence of multi-drug resistance, alternatives to conventional antimicrobial therapy are needed. this study aims to investigate the in vitro pharmacological interactions between essential oils (considered valuable as natural therapeutic treatments) and conventional antimicrobials (ciprofloxacin/amphotericin b) when used in combination. | 2009 | 19187494 |
| evaluation of a digoxigenin-labelled probe for detection of aeromonas spp. | an outer membrane protein-based digoxigenin (dig)-labelled dna probe was developed for the specific detection of aeromonas sp. from food/environmental/clinical samples. dot blot reaction answered for all the aeromonas isolates and was negative for escherichia coli, pseudomonas sp., klebsiella sp., vibrio parahaemolyticus, v. harveyi, v. alginolyticus, v. vulnificus. edwardsiella tarda and staphylococcus sp. as this protein is highly conserved in various aeromonas species, the probe has the poten ... | 2009 | 19187505 |
| antimicrobial susceptibility pattern of bacterial pathogens causing urinary tract infections in a saudi arabian hospital. | the study describes the pathogens causing urinary tract infections (uti) and the antimicrobial susceptibility pattern of health care-associated (hca) and community-acquired (ca) isolates. of the total of 3,989 nonrepetitive urinary cultures, 4.7% (n=188) were hca and 95.3% (n=3,801) were ca isolates. gram-negative organisms totaled 3,607 (90.4%) vs. 9.6% gram-positive organisms. in ca-uti, escherichia coli, klebsiella pneumoniae and enterococcus faecalis constituted 66, 11.4, and 5.4%, respectiv ... | 2009 | 19188712 |
| nosocomial infections in pediatric cardiovascular surgery patients: a 4-year survey. | to determine the prevalence, characteristics, and risk factors for nosocomial infections (nis) in children postcardiac surgery and hospitalized in a pediatric intensive care unit (picu). | 2009 | 19188871 |
| multiple organ dysfunction syndrome in a dog with klebsiella pneumoniae septicemia. | multiple organ dysfunction syndrome is defined as the presence of altered organ function in an acutely ill patient such that homeostasis could not be mantained without intervention. it is reported that mortality rate in humans with 4 organ systems failing reaches nearly 100%, while there are few publications documenting this syndrome in dogs. to the author's knowledge, this is the first report that describes the clinical manifestations and the favourable outcome to intensive medical care in a do ... | 2009 | 19189251 |
| characterization and expression analysis of a gene cluster for nitrate assimilation from the yeast arxula adeninivorans. | in arxula adeninivorans nitrate assimilation is mediated by the combined actions of a nitrate transporter, a nitrate reductase and a nitrite reductase. single-copy genes for these activities (aynt1, aynr1, ayni1, respectively) form a 9103 bp gene cluster localized on chromosome 2. the 3210 bp ayni1 orf codes for a protein of 1070 amino acids, which exhibits a high degree of identity to nitrite reductases from the yeasts pichia anomala (58%), hansenula polymorpha (58%) and dekkera bruxellensis (5 ... | 2009 | 19191338 |
| structure and insight into blue light-induced changes in the blrp1 bluf domain. | bluf domains (sensors of blue light using flavin adenine dinucleotide) are a group of flavin-containing blue light photosensory domains from a variety of bacterial and algal proteins. while spectroscopic studies have indicated that these domains reorganize their interactions with an internally bound chromophore upon illumination, it remains unclear how these are converted into structural and functional changes. to address this, we have solved the solution structure of the bluf domain from klebsi ... | 2009 | 19191473 |
| neopyrrolomycins with broad spectrum antibacterial activity. | three new antibiotics, neopyrrolomycins b (1), c (2), and d (3), with potent activity against gram-positive pathogens were discovered. they exhibited mic values < 1 microg/ml versus a number of resistant strains. the compounds were obtained from the ethyl acetate extracts of a streptomyces sp. after purification by column chromatography and rp-hplc. their structures were elucidated using x-ray crystallography (1) and nmr spectroscopy (2 and 3). | 2009 | 19191549 |
| invasive pneumococcal disease in children aged <5 years admitted to 3 urban hospitals in ibadan, nigeria. | streptococcus pneumoniae remains a major cause of childhood morbidity and mortality in the world. the introduction of pneumococcal conjugate vaccine in developing countries will be facilitated by a clearer understanding of the disease burden for bacterial causes of pneumonia and meningitis and the prevalent serotypes of s. pneumoniae. | 2009 | 19191615 |
| atrazine degradation by stable mixed cultures enriched from agricultural soil and their characterization. | the aim of this work was to enrich stable mixed cultures from atrazine-contaminated soil. the cultures were examined for their atrazine biodegradation efficiencies in comparison with j14a, a known atrazine-degrading strain of agrobacterium radiobacter. the cultures were also characterized to identify community structure and bacterial species present. | 2009 | 19191954 |
| potential pathogens and effective disinfectants on public telephones at a large urban united states university. | telephones can carry potential bacterial pathogens, posing a risk for transfer of pathogens to users' hands. this study examined 25 mouthpieces of public telephones at a large urban u.s. university located in an area of rising incidence of community-acquired staphylococcal infections. coagaulase-negative staphylococci were most commonly isolated (64% of mouthpieces). potential pathogens isolated included staphylococcus aureus, vancomycin-susceptible enterococcus, and klebsiella ozaenae. the effi ... | 2009 | 19192741 |
| comparison of 2002-2006 optama programs for us hospitals: focus on gram-negative resistance. | resistance among gram-negative bacteria is increasing within the us. | 2009 | 19193582 |
| impact of superinfection on hospital length of stay and costs in patients with ventilator-associated pneumonia. | ventilator-associated pneumonia (vap) increases length of stay (los) in vap versus non-vap patients, but los differences among vap patients remain unexplained. we explored the economic impact of developing a respiratory superinfection while being treated for vap. this was a retrospective, observational cohort study conducted in 74 patients discharged between january 2004 and july 2005 identified as having vap. using detailed, chart-abstracted demographic and hospital-course data--including antib ... | 2009 | 19199193 |
| isolation and identification of antibacterial compounds from thymus kotschyanus aerial parts and dianthus caryophyllus flower buds. | the aerial parts of thymus kotschyanus boiss. and hohen. (lamiaceae) and flower buds of dianthus caryophyllus l. (caryophyllaceae) have been traditionally implemented in the treatment of wounds, throat and gum infections and gastro-intestinal disorder by the indigenous people of northern iraq, although the compounds responsible for the medicinal properties have not been identified. in this study, antibacterial compounds from both plants were isolated and characterized, and the biological activit ... | 2009 | 19200700 |
| neurotoxicity in patients treated with intravenous polymyxin b: two case reports. | two cases of reversible neurotoxicity associated with the administration of intravenous polymyxin b are described. | 2009 | 19202043 |
| role of mycoplasma pneumoniae infection in acute exacerbations of chronic obstructive pulmonary disease. | eighty per cent of the cases of acute exacerbation of chronic obstructive pulmonary disease (aecopd) have an infective aetiology, atypical bacteria including mycoplasma pneumoniae accounting for 5-10 % of these. however, the importance of association of m. pneumoniae with episodes of aecopd still remains doubtful. the present study was therefore undertaken to delineate the extent of involvement of m. pneumoniae in patients with aecopd at a referral hospital in delhi, india. sputum samples and th ... | 2009 | 19208881 |
| ventilator-associated pneumonia in a paediatric intensive care unit in a developing country with high hiv prevalence. | to obtain preliminary prevalence, aetiological and outcome data on south african paediatric patients with ventilator-associated pneumonia (vap). | 2009 | 19210603 |
| regioselective synthetic approaches towards 1,2,8,9-tetraazadispiro[4.1.4.2]trideca-2,9-dien-6-ones of potential antimicrobial properties. | reaction of 2,5-bis(arylmethylidene)cyclopentanones 1a-d with nitrilimines (generated in situ via triethylamine dehydrohalogenation of the corresponding hydrazonoyl chlorides 2a,b) in 1:2 molar ratio proceeds in a high regioselective manner affording monocycloadducts 3 and dicycloadducts in the form of two isomers 4, 5. single crystal x-ray diffraction studies of the isolated crystalline form of 3c support the established structure and indicate that the formed product is 7e, 4s, 5r. antimicrobia ... | 2009 | 19211175 |
| ertapenem resistance among extended-spectrum-beta-lactamase-producing klebsiella pneumoniae isolates. | ertapenem resistance in klebsiella pneumoniae is rare. we report on an ertapenem-nonsusceptible phenotype among 25 out of 663 (3.77%) extended-spectrum-beta-lactamase (esbl)-producing k. pneumoniae isolates in a multicenter israeli study. these isolates originated from six different hospitals and were multiclonal, belonging to 12 different genetic clones. repeat testing using etest and agar dilution confirmed ertapenem nonsusceptibility in only 15/663 (2.3%) of the isolates. the molecular mechan ... | 2009 | 19213695 |
| acute lower respiratory tract infections in children. | acute lower respiratory tract infection (alrti) is a common illness, but there have been relatively few studies of the bacterial etiology in developing countries. nasopharyngeal aspirates of 70 children under 10 years of age with alrti were cultured for aerobic bacterial pathogens. klebsiella pneumoniae was the commonest organism (32.2%) isolated followed by s. pneumoniae (10%), e. coli (10%), p. aeruginosa (5.7%), s. aureus (2.8%) and h. influenzae (1.4%). there were significantly more bacteria ... | 2009 | 19213982 |
| antimicrobial activity of five herbal extracts against multi drug resistant (mdr) strains of bacteria and fungus of clinical origin. | antimicrobial activities of the crude ethanolic extracts of five plants were screened against multidrug resistant (mdr) strains of escherichia coli, klebsiella pneumoniae and candida albicans. atcc strains of streptococcus mutans, staphylococcus aureus, enterococcus faecalis, streptococcus bovis, pseudimonas aeruginosa, salmonella typhimurium, escherichia coli, klebsiella pneumoniae and candida albicans were also tested. the strains that showed resistance against the maximum number of antibiotic ... | 2009 | 19214149 |
| evaluation of the capability of the vitek 2 system to detect extended-spectrum beta-lactamase-producing escherichia coli and klebsiella pneumoniae isolates, in particular with the coproduction of ampc enzymes. | a total of 317 klebsiella pneumoniae and 291 escherichia coli nonduplicate isolates were tested by the vitek 2 system to evaluate its capability to detect extended-spectrum beta-lactamases (esbls) among putative esbl-producing isolates, in particular those with the coproduction of ampc enzymes. beta-lactamases produced by the test isolates had been characterised. the sensitivity and specificity for esbls were 98.9% and 98.5%, respectively. ninety of the isolates were ampc (cmy-2, cmy-8 or dha-1) ... | 2009 | 19214606 |
| a novel approach for salvaging infected prosthetic mesh after ventral hernia repair. | salvaging infected prosthetic material after ventral hernia repair is rarely successful. most cases require mesh excision and complex abdominal wall reconstruction, with variable success rates. we report two cases of mesh salvage with a novel use of percutaneous drainage and antibiotic irrigation. | 2009 | 19214650 |
| salmochelin, the long-overlooked catecholate siderophore of salmonella. | salmochelin is a c-glucosylated enterobactin produced by salmonella species, uropathogenic and avian pathogenic escherichia coli strains, and certain klebsiella strains. it was the first glucosylated siderophore described. the glucosylation has been interpreted as a bacterial evasion mechanism against the mammalian catecholate siderophore-binding protein siderocalin (ngal-lipocalin). the synthesis, excretion, and uptake of salmochelin requires five genes, irobcden, and also the enterobactin bios ... | 2009 | 19214756 |
| first report of acute purulent pericarditis by capsule genotype k1 klebsiella pneumoniae in an alcoholic patient. | 2009 | 19216945 | |
| fluorescence in situ hybridization for intracellular localization of nifh mrna. | few reports on in situ mrna detection in bacteria have been published, even though a major aim in environmental microbiology is to link function/activity to the identity of the organisms. this study reports a reliable approach for the in situ detection of nifh mrna using fluorescence hybridization based on a previously described protocol for pmoa. nifh codes for a dinitrogenase reductase, a key enzyme in dinitrogen fixation. nifh mrna was hybridized with a digoxigenin-labelled polynucleotide pro ... | 2009 | 19217232 |
| emergence of clonally related klebsiella pneumoniae isolates of sequence type 258 producing plasmid-mediated kpc carbapenemase in norway and sweden. | the class a carbapenemase kpc has disseminated rapidly worldwide, challenging the treatment of gram-negative infections. this report describes the first kpc-producing klebsiella pneumoniae isolates identified in norway (n=6) and the second isolate from sweden. | 2009 | 19218573 |
| [relevance of esbl-producing pathogens for clinical surgery: diagnostics, therapy, and prevention]. | multiresistant, extended spectrum beta lactamase (esbl)-producing pathogens are an increasing problem in daily clinical life. this paper summarizes the development of resistance as well as epidemiology, diagnostics, and treatment of esbl-producing micro-organisms. we analyzed microbiological data collected at the grosshadern clinic in germany between 1996 and 2007, in order to assess the importance of these micro-organisms to medical practice and surgical care units. | 2009 | 19219416 |
| combined porin loss and extended spectrum beta-lactamase production is associated with an increasing imipenem minimal inhibitory concentration in clinical klebsiella pneumoniae strains. | for this study, 150 clinical isolates of klebsiella pneumoniae were collected from one hospital in beijing, china, and assayed for minimal inhibitory concentration (mic) of imipenem. to elucidate the mechanisms responsible for imipenem mic variation among extended-spectrum beta-lactamase (esbl)-positive and -negative k. pneumoniae strains, a variety of beta-lactamase genes (bla(tem), bla(ctx-m), bla(shv), and bla(oxa)) were screened by polymerase chain reaction (pcr). the outer membrane profile ... | 2009 | 19219497 |
| isolation and characterization of biocides resistant bacteria from dental unit water line biofilms. | six biocides resistant isolates were isolated from dental unit water lines (duwl) in pakistan. all isolates could tolerate 150 microg ml(-1 )of biocides (5.25% sodium hypocholrite, 35% h2o2, 4% tween 20, 1% povidine iodine, 0.2% chlorohexidine gluconate, 1% ethylene di-amino tetra acetic acid and 1% phenol) on l-agar and 100 microg ml(-1 )in l-broth. the growth rate of all isolates was determined by generating growth curves at 37 degrees c for 48 h. the isolates were found to differ in growth ra ... | 2009 | 19219903 |
| flexible microfluidic device for mechanical property characterization of soft viscoelastic solids such as bacterial biofilms. | we introduce a flexible microfluidic device to characterize the mechanical properties of soft viscoelastic solids such as bacterial biofilms. in the device, stress is imposed on a test specimen by the application of a fixed pressure to a thin, flexible poly(dimethyl siloxane) (pdms) membrane that is in contact with the specimen. the stress is applied by pressurizing a microfabricated air channel located above the test area. the strain resulting from the applied stress is quantified by measuring ... | 2009 | 19219968 |
| antibiotic prophylaxis tailored to local organisms reduces percutaneous gastrostomy site infection. | current recommendations for the choice of antibiotic prophylaxis prior to percutaneous endoscopic gastrostomy (peg) insertion may not be suitable in all situations. | 2009 | 19222613 |
| prospective observational study of the impact of vim-1 metallo-beta-lactamase on the outcome of patients with klebsiella pneumoniae bloodstream infections. | vim-1-producing klebsiella pneumoniae (vpkp) is an emerging pathogen. a prospective observational study was conducted to evaluate the importance of vim production on outcome of patients with k. pneumoniae bloodstream infections (bsis). consecutive patients with k. pneumoniae bsis were identified and followed up until patient discharge or death. a total of 162 patients were included in the analysis; 67 (41.4%) were infected with vpkp, and 95 were infected with non-vpkp. fourteen of the patients i ... | 2009 | 19223638 |
| metabolic pathway analysis of glycerol metabolism in klebsiella pneumoniae incorporating oxygen regulatory system. | it is well known that environmental and genetic perturbations have major effects on the metabolic behavior of cells. in this work, a model that utilizes existing knowledge of oxygen and redox sensing/regulatory system to assist elementary flux modes (efms) has been developed and was carried out to predict the metabolic potential of klebsiella pneumoniae for the production of 1,3-propanediol (1,3-pd) under anaerobic and aerobic conditions. it was found that the theoretical optimal 1,3-pd yield co ... | 2009 | 19224565 |
| sugar nucleotide recognition by klebsiella pneumoniae udp-d-galactopyranose mutase: fluorinated substrates, kinetics and equilibria. | a series of selectively fluorinated and other substituted udp-d-galactose derivatives have been evaluated as substrates for klebsiella pneumoniae udp-d-galactopyranose mutase. this enzyme, which catalyses the interconversion of the pyranose and furanose forms of galactose as its udp adduct, is a prospective drug target for a variety of microbial infections. we show that none of the 2''-, 3''- or 6''-hydroxyl groups of udp-d-galactopyranose are essential for substrate binding and turnover. howeve ... | 2009 | 19225684 |
| dissemination of a bla(vim-2)-carrying integron among enterobacteriaceae species in mexico: report from the sentry antimicrobial surveillance program. | three vim-2-producing enterobacteriaceae (two enterobacter cloacae and one klebsiella oxytoca) isolates recovered from patients in a mexican hospital were characterized during the sentry antimicrobial surveillance program (2005-2007). these strains carried identical bla(vim-2) integrons in a 450-kb plasmid. the interspecies dissemination of this bla(vim-2)-harboring element emphasizes the potential for spread of genetic structures carrying metallo-beta-lactamases that could limit therapeutic opt ... | 2009 | 19228113 |
| species distribution and antimicrobial susceptibility of gram-negative aerobic bacteria in hospitalized cancer patients. | nosocomial infections pose significant threats to hospitalized patients, especially the immunocompromised ones, such as cancer patients. | 2009 | 19228413 |
| strongyloides stercoralis hyperinfection presenting as acute respiratory failure and gram-negative sepsis in a patient with astrocytoma. | in developing countries, strongyloides stercoralis infection is a common cause of morbidity and mortality. death from strongyloidosis can result from hyperinfection or disseminated disease. infections due to s. stercoralis are unusual in saudi arabia and are usually diagnosed in immigrants from endemic areas. we report a case in which s. stercoralis was isolated from the sputum of a patient with gram-negative sepsis and respiratory failure, and review the salient features of this disease. a high ... | 2009 | 19231269 |
| outbreak of ctx-m-15-producing klebsiella pneumoniae in the intensive care unit of a french hospital. | the ctx-m-15 extended spectrum beta-lactamase (esbl)-producing klebsiella pneumoniae isolates were identified in 36 patients hospitalized from december 2006 to september 2007 in the medical intensive care unit (icu) of the bicêtre hospital, south paris, france. the incidence of colonization and/or infection was 4.8%. eighty-nine percent of the esbl-producing k. pneumoniae isolates were acquired in the icu, and only 8.3% of the patients were infected. pulsed field gel electrophoresis (pfge) analy ... | 2009 | 19231938 |
| crystal structure of the full-length sorbitol operon regulator sorc from klebsiella pneumoniae: structural evidence for a novel transcriptional regulation mechanism. | sorc transcriptional regulators are common regulators in prokaryotes. here we report the first crystal structure of a full-length sorc, the sorbitol operon regulator sorc from klebsiella pneumoniae, the prototype of its family. sorc was found to be a homotetramer (which seems to be the biologically active form) that is able to recognize its dna operator. the tetramer can be regarded as a dimer of dimers, with each dimer being composed of two identical subunits in different conformations. the dna ... | 2009 | 19232357 |
| prevalence of 16s rrna methylase genes in klebsiella pneumoniae isolates from a chinese teaching hospital: coexistence of rmtb and arma genes in the same isolate. | 16s rrna methylase-mediated high-level resistance to aminoglycosides has been reported recently in clinical isolates of gram-negative bacilli from several countries. twenty-one (6.2%, 21/337) of 337 isolates of klebsiella pneumoniae from a teaching hospital in wenzhou, china, were positive for 16s rrna methylase genes (3 for arma, 13 for rmtb, 5 for both arma and rmtb) and highly resistant to gentamicin, amikacin, and tobramycin (mics, > or =256 microg/ml). nineteen of 21 isolates harboring 16s ... | 2009 | 19232867 |
| molecular mechanisms disrupting porin expression in ertapenem-resistant klebsiella and enterobacter spp. clinical isolates from the uk. | the aim of this study was to investigate relatedness and molecular mechanism(s) of ertapenem resistance in clinical isolates of klebsiella spp. (n = 28) and enterobacter spp. (n = 27) referred from multiple hospitals to the uk national reference laboratory. | 2009 | 19233898 |
| characterization of a beta-glucoside operon (bgc) prevalent in septicemic and uropathogenic escherichia coli strains. | escherichia coli strains, in general, do not ferment cellobiose and aryl-beta-d-glucosidic sugars, although "cryptic" beta-d-glucoside systems have been characterized. here we describe an additional cryptic operon (bgc) for the utilization of cellobiose and the aryl-beta-d-glucosides arbutin and salicin at low temperature. the bgc operon was identified by the characterization of beta-glucoside-positive mutants of an e. coli septicemia strain (i484) in which the well-studied bgl (aryl-beta-d-gluc ... | 2009 | 19233952 |
| characterization of a modified nitrogenase fe protein from klebsiella pneumoniae in which the 4fe4s cluster has been replaced by a 4fe4se cluster. | the azotobacter vinelandii nifs gene product has been used with selenocysteine to reconstitute klebsiella pneumoniae nitrogenase fe protein. chemical analysis and extended x-ray absorption fine structure (exafs) spectroscopy show that the 4fe4s cluster present in the native protein is replaced by a 4fe4se cluster. as well, exafs spectroscopy shows that the bond lengths to the cysteine thiolate ligands shrink by 0.05 a (from 2.28 to 2.23 a) upon reduction, whereas the fe-fe distance is essentiall ... | 2009 | 19234722 |
| determination of oropharyngeal pathogenic colonization in the elderly community. | pneumonia has become the predominant cause of death for the elderly. it is critical to determine the status of oropharyngeal pathogen colonization in the elderly when treating pneumonia. to explore the efficient approaches to treat age-related pneumonia, we determined the status of oropharyngeal pathogenic colonization in the elderly community. | 2009 | 19236811 |
| antimicrobial susceptibility pattern of urinary tract pathogens. | microbial drug resistance is a major problem in the treatment of infectious diseases worldwide. the purpose of this survey is to determine the prevalence of the type of bacterial agents that cause urinary infection and to assess the antimicrobial sensitivity pattern in the urmia medical university, iran. in the period between 2005 and 2006, urine cultures collected were analyzed. positive culture was defined as growth of a single bacterial species with colony count of > 100,000 cfu/ml. stratific ... | 2009 | 19237813 |
| 1h-nuclear magnetic resonance spectroscopy for identifying and quantifying common uropathogens: a metabolic approach to the urinary tract infection. | to address the shortcomings of urine culture for the diagnosis of urinary tract infection (uti), we used 1h-nuclear magnetic resonance (nmr) spectroscopy for identifying and quantifying escherichia coli, pseudomonas aeruginosa, klebsiella pneumonia and proteus mirabilis. | 2009 | 19239442 |
| consequences of increased antibacterial consumption and change in pattern of antibacterial use in danish hospitals. | antibacterial consumption is increasing in many countries around the world, and it is increasingly recognized as the main reason for the emergence of resistance. this study was implemented to analyse antibacterial consumption in public hospitals in denmark during 2001-07 as a follow-up on a prior analysis and furthermore, to investigate the consequences of the occurrence of resistance. | 2009 | 19240071 |
| role of tolc in klebsiella oxytoca resistance to antibiotics. | the gram-negative human pathogen klebsiella oxytoca is often resistant to several antibiotics such as fluoroquinolones, erythromycin, tetracycline, chloramphenicol and others. the aim of this study was to look at the mechanisms leading to this resistance and particularly the role of tolc and efflux mechanisms in determining resistance. | 2009 | 19240073 |
| in vitro activity of tigecycline against multidrug-resistant enterobacteriaceae isolates from a belgian hospital. | bacterial resistance among gram-negative pathogens is a challenging clinical problem. tigecycline has been developed specifically to overcome resistance. the aim of this study was to assess the in vitro activity of tigecycline against esbl-producing escherichia coli, esbl-producing klebsiella spp., and multidrug-resistant enterobacter spp. between may 2007 and march 2008, 26 strains of esbl-producing escherichia coli, 10 strains of esbl-producing klebsiella spp., and 27 strains of multidrug-resi ... | 2009 | 18802728 |
| post-consumer use efficacies of preservatives in personal care and topical drug products: relationship to preservative category. | ninety-six used personal care and topical otc drug items collected from consumers in the usa were examined for the presence of microbial contaminants. of the eye and face product type containing global preservative chemistries (i.e., acceptable for use in japan without major restrictions), 55% yielded numbers of microorganisms in excess of 500 cfu/g (p < 0.1814). for the mascara products with global preservative chemistries, 79% yielded numbers of microorganisms in excess of 500 cfu/g (p < 0.024 ... | 2009 | 18802729 |
| lipase-catalyzed production of a bioactive fatty amide derivative of 7,10-dihydroxy-8(e)-octadecenoic acid. | enzymatic syntheses of fatty amides are of considerable interest due to their wide ranging industrial applications in detergents, shampoo, cosmetics and surfactant formulations. amidation reaction of candida antarctica lipase b (calb) was investigated for direct amidation of carboxylic acid in organic solvent. calb-mediated production of a novel secondary amide was carried out by reacting the hydroxy oleic acid derivative, 7,10-dihydroxy-8(e)-octadecenoic acid (dod), with n-methylethanol amine i ... | 2009 | 18793843 |
| mycotic aneurysm caused by gas-forming serotype k5 klebsiella pneumoniae. | we describe the first documented case of mycotic aneurysm caused by gas-forming serotype k5, and rmpa and iuc positive klebsiella pneumonia with a hypermucoviscosity phenotype in a diabetic patient. the patient received ceftriaxone for one month and underwent aorto-bi-iliac grafting and inferior mesenteric artery reimplantation and recovered well. | 2009 | 18774741 |
| catheter-associated and nosocomial urinary tract infections: antibiotic resistance and influence on commonly used antimicrobial therapy. | the objective is to evaluate resistance between community-acquired urinary tract infections (cauti), nosocomialy-acquired urinary tract infections (nauti), and empirical therapy adequacy. e. coli is the predominant pathogen of both cauti and nauti, followed by klebsiella spp. in nauti and pseudomonas spp. in catheter-associated urinary tract infections. the highest level of general resistance was found among isolates of nauti and catheter-associated uti followed by cauti isolates. absolute or hi ... | 2009 | 18787972 |
| act-3, a novel plasmid-encoded class c beta-lactamase in a klebsiella pneumoniae isolate from china. | 2009 | 18789849 | |
| synthesis, characterization and antimicrobial activity of co(ii), zn(ii) and cd(ii) complexes with n-benzyloxycarbonyl-s-phenylalanine. | in this paper the first complexes of m(2+) ions (m(2+) = zn(2+), cd(2+) and co(2+)) with n-benzyloxycarbonyl-s-phenylalaninato ligand (1-3) are described. the new complexes were characterized by means of elemental analysis, ir and uv-vis spectroscopy, molar conductivity measurements and (1)h, (13)c and (15)n nmr spectroscopy (1d and 2d). the co(ii) complex adopts an octahedral geometry, and the zn(ii) and cd(ii) complexes adopt a tetrahedral one. for the first time, the antimicrobial activity of ... | 2009 | 18760509 |
| synthesis, structure and biological activity of copper(ii) complexes of 4-(2-pyridylmethyl)-1,7-dimethyl-1,4,7-triazonane-2,6-dione and 4-(2-pyridylethyl)-1,7-dimethyl-1,4,7-triazonane-2,6-dione. | four mononuclear copper(ii) complexes 1-4 have been synthesized with two new n-functionalized macrocyclic ligands l(1) and l(2). all complexes are well characterized by various spectroscopic techniques, elemental analyses and conductivity measurements. results suggest that cu(ii) ion has n(2)o coordination from ligand and s(2) from two coordinated solvent molecules (sch(3)cn for 1 and 3 while ch(3)oh for 2 and 4). the crystal structure of a representative complex 3 strengthen the proposed formul ... | 2009 | 18775587 |
| infections in a surgical intensive care unit of a university hospital in greece. | we aimed to evaluate the clinical and microbiological characteristics of the patients who developed an infection in our surgical intensive care unit (sicu). | 2009 | 18775663 |
| computational method for inferring objective function of glycerol metabolism in klebsiella pneumoniae. | flux balance analysis (fba) is an effective tool in the analysis of metabolic network. it can predict the flux distribution of engineered cells, whereas the accurate prediction depends on the reasonable objective function. in this work, we propose two nonlinear bilevel programming models on anaerobic glycerol metabolism in klebsiella pneumoniae (k. pneumoniae) for 1,3-propanediol (1,3-pd) production. one intends to infer the metabolic objective function, and the other is to analyze the robustnes ... | 2009 | 18804419 |
| a dormancy state in nonspore-forming bacteria. | while cultivation is a convenient way of proliferating and understanding bacteria, studies have shown the formation of nonculturable cells in nonspore-forming bacteria in response to environmental stress and thus in turn have generated immense interest. whether these cells are in a state of dormancy or in a stage preceding cell death has been considered of paramount importance for the past couple of decades. in this study, osmotic-stress-induced dormant bacterial cells were separated by cell sor ... | 2009 | 18815783 |
| biodegradation of chlorpyrifos in soil by enriched cultures. | three aerobic bacterial consortia, ac, bc, and dc, developed from pesticide-contaminated soils of punjab were able to degrade chlorpyrifos after 21 days of incubation in basal medium by 54, 46, and 61% and chlorpyrifos (50 mg/l) in soil after 30 days by 50, 56, and 64%. pseudomonas aeruginosa, bacillus cereus, klebsiella sp., and serratia marscecens obtained from these consortia showed 84, 84, 81, and 80% degradation of chlorpyrifos (50 mg/l) in liquid medium after 20 days and 92, 60, 56, and 37 ... | 2009 | 18815830 |
| characterisation of aerobically grown non-spore-forming bacteria from paper mill pulps containing recycled fibres. | a total of 179 non-spore-forming bacteria aerobically growing on nutrient agar, plate count agar or in specific enrichment conditions for salmonella, campylobacteria, listeria, yersinia or staphylococci, were isolated from 16 untreated paper mill pulps. after phenotypical screening the isolates were characterised by automated ribotyping and partial sequencing of the 16s rrna gene. they could be divided into seven taxonomical classes representing 63 taxa (species): actinobacteria (11 species), ba ... | 2009 | 18820960 |
| synthesis and biological activities of new hydrazide derivatives. | the synthesis of a new series of imidazo[1,2-a]pyrazine-2-carboxylic acid arylidene-hydrazides is described. the chemical structures of the compounds were elucidated by ir, (1)h-nmr, fab(+)-ms spectral data. their biological activity against various bacteria, fungi species, and mycobacterium tuberculosis was investigated. antibacterial activity was measured against escherichia coli (nrrl b-3704), staphylococcus aureus (nrrl b-767), salmonella typhimurium (nrrl b-4420), proteus vulgaris (nrll b-1 ... | 2009 | 18825530 |
| design, synthesis and in vitro microbiological evaluation of 6,6-dimethyl-7,9-diaryl-1,2,4,8-tetraazaspiro[4.5]decan-3-thiones--a new series of 'tailor-made' compounds. | some novel 'tailor-made' compounds, 6,6-dimethyl-7,9-diaryl-1,2,4,8-tetraazaspiro[4.5]decan-3-thiones 23-27 have been studied for their in vitro antibacterial activity against staphylococcus aureus, beta-heamolytic streptococcus, vibreo cholerae, salmonella typhii, shigella felxneri, escherichia coli, klebsiella pneumonia, pseudomonas aeruginosa and anti-fungal activity against aspergillus flavus, mucor, rhizopus and microsporum gypsuem. compounds 24 and 25 exerted potent antibacterial activity ... | 2009 | 18830884 |
| in vitro susceptibilities of aerobic and facultatively anaerobic gram-negative bacilli isolated from patients with intra-abdominal infections worldwide: 2005 results from study for monitoring antimicrobial resistance trends (smart). | the study for monitoring antimicrobial resistance trends (smart) is examining aerobic and facultatively anaerobic gram-negative bacilli (gnb) isolated from intra-abdominal infections. this report summarizes the 2005 annual data. | 2009 | 18831681 |
| using active microbiologic surveillance and enhanced infection control measures to control an outbreak of health care-associated extended-spectrum beta-lactamase-producing klebsiella pneumoniae infections--new jersey, 2007. | between april and june 2007, an outbreak of extended-spectrum beta-lactamase-producing klebsiella pneumoniae infections occurred in an intensive care unit in new jersey. the outbreak was contained through active microbiologic surveillance, contact precautions, cohorting, and frequent room cleaning. this outbreak demonstrates the importance of rapid response in identifying and isolating patients to prevent further transmission. | 2009 | 18834744 |
| susceptibility patterns of bacterial isolates from hospitalised patients with respiratory tract infections (moxiaktiv study). | the objective of this study was to determine: (i) the prevalence of resistance in current clinical isolates of streptococcus pneumoniae, staphylococcus aureus, haemophilus influenzae, moraxella catarrhalis and klebsiella pneumoniae; (ii) the prevalence of production of extended-spectrum beta-lactamases (esbls) and methicillin resistance in s. aureus; and (iii) regional differences in the prevalence of esbl production and clonality of k. pneumoniae isolates. pathogens causing respiratory tract in ... | 2009 | 18835763 |
| effects of over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase on bioconversion of glycerol into 1,3-propandediol by klebsiella pneumoniae under micro-aerobic conditions. | glycerol dehydrogenase (gdh) and 1,3-propanediol (1,3-pd) oxidoreductase had been proved two key enzymes for 1,3-pd production by klebsiella pneumoniae. fed-batch fermentations of the recombinant k. pneumoniae strains, over-expressing the two enzymes individually, were carried out under micro-aerobic conditions, and the behaviors of the recombinants were investigated. results showed that over-expression of 1,3-pd oxidoreductase did not affect the concentration of 1,3-pd. however, it enhanced the ... | 2009 | 18682988 |
| mitracarpus frigidus aerial parts exhibited potent antimicrobial, antileishmanial, and antioxidant effects. | the crude extract and the hexane, ch(2)cl(2), etoac, n-buoh, and hydromethanolic fractions of the aerial parts of mitracarpus frigidus were evaluated against promastigote forms of two species of leishmania (l. chagasi and l. amazonensis), 11 strains of bacteria (staphylococcus aureus, pseudomonas aeruginosa, salmonella enterica sorovar tythimurium, shigella sonnei, klebsiella pneumoniae, escherichia coli, micrococcus luteus, enterococcus faecalis, enterobacter cloacae, streptococcus pyogenes and ... | 2009 | 18644325 |
| gene cloning, expression, and characterization of a novel phytase from dickeya paradisiaca. | a novel phytase gene, appa, was isolated by degenerate polymerase chain reaction (pcr) and thermal asymmetric interlaced pcr from dickeya paradisiaca. the full-length appa comprises 1278 bp and encodes 425 amino acid residues, including a 23-residue putative n-terminal signal peptide. the deduced amino acid sequence of appa reveals the conserved motifs rhgxrxp and hd, which are typical of histidine acid phosphatases; significantly, appa shows maximum identity (49%) to a phytase from klebsiella p ... | 2009 | 18679591 |
| antimicrobial resistance patterns of urinary tract pathogens and rationale for empirical therapy in turkish children for the years 2000-2006. | in patients with suspected urinary tract infection (uti), antibiotic treatment is usually started empirically, before urine culture results are available. unfortunately, antibiotic resistance has become an increasingly pressing clinical issue in many countries. the objective of this study was to assess the changing susceptibility of urinary pathogens to commonly used antimicrobials in a six-year period to evaluate the options for empirical antibiotic therapy in children with community acquired u ... | 2009 | 18704743 |
| proteolytic activity in stored aerobic granular sludge and structural integrity. | aerobic granules lose stability during storage. the goal of this work was to highlight the main cause of stability loss for stored granules as intracellular protein hydrolysis. the quantity of extracellular proteins was noted to be significantly lower during granule storage, and protease enzyme activities were correspondingly higher in the cores of stored granules. the proteolytic bacteria, which secrete highly active protease enzymes, were for the first time isolated and characterized by analyz ... | 2009 | 18614356 |
| causative agents and antimicrobial susceptibilities of urinary tract infections in the northwest of iran. | the empirical therapy of urinary tract infections (uti) relies on the predictability of the agents causing uti and knowledge of their antimicrobial susceptibility patterns. | 2009 | 18703368 |
| nationwide surveillance of antimicrobial resistance among enterobacteriaceae in intensive care units in taiwan. | to determine the antimicrobial resistance profiles among clinical isolates of enterobacteriaceae in taiwanese intensive care units (icus), a national surveillance of antibiotic resistance among important enterobacteriaceae was conducted from september 2005 through november 2005 at the icus of ten major teaching hospitals in taiwan. a total of 574 enterobacteriaceae isolates recovered from various clinical samples of our icu patients were submitted for in vitro test. minimum inhibitory concentrat ... | 2009 | 18716805 |
| susceptibility of common aerobic pathogens to tigecycline: results of a surveillance study in germany. | tigecycline is a novel antimicrobial agent for parenteral use encompassing a broad spectrum of bacterial pathogens, including multi-resistant organisms. here, we report the results of the first nationwide surveillance trial that was conducted in order to evaluate the susceptibility of bacterial isolates to tigecycline in a european country prior to its clinical use. a total of 2,610 gram-positive and gram-negative organisms recovered from hospitalized patients were tested. minimum inhibitory con ... | 2009 | 18716808 |
| rapid detection of bla(kpc)-positive klebsiella pneumoniae in a clinical setting. | 2009 | 18719955 | |
| effect of electrical current on the activities of antimicrobial agents against pseudomonas aeruginosa, staphylococcus aureus, and staphylococcus epidermidis biofilms. | bacterial biofilms are resistant to conventional antimicrobial agents. prior in vitro studies have shown that electrical current (ec) enhances the activities of aminoglycosides, quinolones, and oxytetracycline against pseudomonas aeruginosa, klebsiella pneumoniae, staphylococcus epidermidis, escherichia coli, and streptococcus gordonii. this phenomenon, known as the bioelectric effect, has been only partially defined. the purpose of this work was to study the in vitro bioelectric effect on the a ... | 2009 | 18725436 |
| evaluation of screening methods to detect plasmid-mediated ampc in escherichia coli, klebsiella pneumoniae, and proteus mirabilis. | there are currently no standardized phenotypic methods for the screening and detection of ampc enzymes. this study aimed to evaluate different methods to detect ampc enzymes in escherichia coli, klebsiella spp., and proteus spp., comparing the results from two disk-based methods and an agar dilution method. ampc activity was determined for 255 clinical isolates by use of a three-dimensional enzyme assay combined with a multiplex pcr assay for plasmid-borne ampc genes. these results were compared ... | 2009 | 18955528 |
| plasmid-mediated 16s rrna methylases in aminoglycoside-resistant enterobacteriaceae isolates in shanghai, china. | high-level resistance to aminoglycosides produced by 16s rrna methylases in enterobacteriaceae isolates was investigated. the prevalences of arma in escherichia coli, klebsiella pneumoniae, and enterobacter cloacae were 0.6%, 3.0%, and 10%, respectively. rmtb was more prevalent than arma. pulsed-field gel electrophoresis patterns indicated that arma and rmtb have spread horizontally and clonally. | 2009 | 18955532 |
| adenovirus-mediated gene transfer of pathogen-associated molecular patterns for cancer immunotherapy. | the delivery of stimulatory signals to dendritic cells (dcs) in the tumor microenvironment could be an effective means to break tumor-induced tolerance. the work presented here evaluates the immunostimulatory properties of pathogen-associated molecular patterns (pamps), microbial molecules which bind toll-like receptors and deliver activating signals to immune cells, when expressed in tumor cells using adenoviral (ad) vectors. in vitro, transduction of a549 tumor cells with ad vectors expressing ... | 2009 | 18949016 |
| enhanced 2,3-butanediol production by klebsiella pneumoniae sdm. | enhanced 2,3-butanediol (bd) production was carried out by klebsiella pneumoniae sdm. the nutritional requirements for bd production by k. pneumoniae sdm were optimized statistically in shake flask fermentations. corn steep liquor powder and (nh(4))(2)hpo(4) were identified as the most significant factors by the two-level plackett-burman design. steepest ascent experiments were applied to approach the optimal region of the two factors and a central composite design was employed to determine thei ... | 2009 | 18949476 |
| a multiresistant klebsiella pneumoniae clinical isolate carrying both ctx-m-15 and vim-1 beta-lactamases, harboured by different plasmids. | 2009 | 18950991 | |
| solution state nmr structure and dynamics of kpompa, a 210 residue transmembrane domain possessing a high potential for immunological applications. | the three-dimensional structure of the outer membrane protein a from klebsiella pneumoniae transmembrane domain was determined by nmr.this protein induces specific humoral and cytotoxic responses, and is a potent carrier protein. this is one of the largest integral membrane proteins(210 residues) for which nearly complete resonance assignment, including side chains, has been achieved so far. the methodology rested on the use of 900 mhz 3d and 4d trosy experiments recorded on a uniformly 15n,13c, ... | 2009 | 18952100 |
| spinal abscess presenting as the initial symptom of crohn's disease. | 2009 | 18931849 | |
| widespread dissemination of aminoglycoside resistance genes arma and rmtb in klebsiella pneumoniae isolates in taiwan producing ctx-m-type extended-spectrum beta-lactamases. | among 235 extended-spectrum beta-lactamase-producing klebsiella pneumoniae (esbl) isolates collected from a nationwide surveillance performed in taiwan, 102 (43.4%) were resistant to amikacin. ninety-two of these 102 (90.2%) isolates were carrying ctx-m-type beta-lactamases individually or concomitantly with shv-type or cmy-2 beta-lactamases. the arma and rmtb alleles were individually detected in 44 and 37 of these 92 isolates, respectively. one isolate contained both arma and rmtb. the coexist ... | 2009 | 18936188 |
| high prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-ib-cr, and qepa among ceftiofur-resistant enterobacteriaceae isolates from companion and food-producing animals. | three kinds of plasmid-mediated quinolone resistance (pmqr) determinants have been discovered and have been shown to be widely distributed among clinical isolates: qnr genes, aac(6')-ib-cr, and qepa. few data on the prevalence of these determinants in strains from animals are available. the presence of pmqr genes in isolates from animals was determined by pcr amplification and dna sequencing. the production of extended-spectrum beta-lactamases (esbls) and ampc beta-lactamases in the strains was ... | 2009 | 18936192 |
| urinary tract infection in preterm infants: the protective role of breastfeeding. | urinary tract infection (uti) differs between preterm and older infants and children in terms of prevalence, clinical presentation, causative organism, and rate of underlying renal anomalies. data on risk factors of uti in preterm infants are limited. the aim of this study was to characterize uti both clinically and microbiologically in premature infants and to define possible risk factors and the role of breastfeeding in its development. this case-control study was conducted in a tertiary-care ... | 2009 | 18936982 |
| a survey on species and prevalence rate of bacterial agents isolated from cockroaches in three hospitals. | the presence of cockroaches has health implications, such as nosocomial infection, as the insects move freely from areas within and around hospitals that may harbor pathogenic organisms. the goals of the present study were to determine species of bacteria isolated from cockroaches found in three tehran hospitals, and to determine distribution of potential vectors by species and sex. the study is descriptive laboratory research. a total of 305 cockroaches from three species were trapped and ident ... | 2009 | 18973441 |