Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| unintended thermal injuries from radiofrequency ablation: protection with 5% dextrose in water. | radiofrequency ablation of hepatic tumors can lead to thermal injury of surrounding structures. both saline and 5% dextrose in water (d5) have been used to displace these surrounding structures before radiofrequency ablation. the purpose of this study was to determine the relative effectiveness of these two fluids for protecting the diaphragm and lung during radiofrequency ablation. | 2006 | 16632684 |
| response of lightly and highly pigmented porcine skin (sus scrofa domestica) to single 3.8-microm laser radiation pulses. | the purpose of this study was to determine the effect of melanin on skin response to single 3.8-microm, 8-micros laser pulses and the difference in lesion formation thresholds. our hypothesis was that pigmentation would play a significant role in skin energy absorption at 3.8 microm. previous studies comparing pigmented and lightly pigmented porcine skin with human skin found that compared with yorkshire pigs, yucatan minipigs were a superior model for laser skin exposure because of their higher ... | 2006 | 16642968 |
| a randomized comparison of manual, mechanical and high-impulse chest compression in a porcine model of prolonged ventricular fibrillation. | elevated coronary perfusion pressure (cpp) during cpr is associated with return of spontaneous circulation (rosc). we compared cpp achieved with three methods of chest compression: manual (man), mechanical (mech) and high-impulse mechanical (hi) in a porcine model of prolonged ventricular fibrillation (vf). we hypothesized that hi (very rapid acceleration of the down-stroke) would produce greater cpps than man or mech, and that hi would also produce a higher rate of rosc. | 2006 | 16563597 |
| high prevalence of trypanosoma brucei gambiense group 1 in pigs from the fontem sleeping sickness focus in cameroon. | to understand the importance of domestic pigs in the epidemiology of human trypanosomiasis, pcr was used to identify trypanosome populations in 133 pigs from the fontem sleeping sickness focus of cameroon. the results from this study show that 73.7% (98/133) of pigs from the fontem area carry at least one trypanosome species. trypanosoma vivax, t. brucei s.l. and t. congolense forest were found in 34.6% (46/133), 40.0% (53/133) and 46.0% (61/133) of the pigs respectively. t. simiae and t. congol ... | 2006 | 16567049 |
| the postnatal development of neocortical neurons and glial cells in the göttingen minipig and the domestic pig brain. | the first mathematically unbiased estimates of neocortical cell numbers are presented from the developing pig brain, including a full description of tissue processing and optimal sampling for application of the stereological optical fractionator method in this species. the postnatal development of neocortical neurons and glial cells from the experimental göttingen minipig was compared with the postnatal development of neocortical neurons in the domestic pig. a significant postnatal development w ... | 2006 | 16574805 |
| histochemical assessment of early myocardial infarction using 2,3,5-triphenyltetrazolium chloride in blood-perfused porcine hearts. | although the chemical mechanism of the triphenyltetrazolium (ttc) reaction, for macroscopic detection of myocardial infarction, has been described previously, literature reports on correct tissue preparation and the use of this technique in intact large animals are lacking. | 2006 | 16580232 |
| facial injury of infant by domestic pig bite: neglect, ignorance, or house designs defect? | 2006 | 16582824 | |
| effect of monopolar radiofrequency treatment over soft-tissue fillers in an animal model: part 2. | monopolar radiofrequency (rf) treatment is used by physicians to heat skin and promote tissue tightening and contouring. cosmetic fillers are used to soften deep facial lines and wrinkles. patients who have had dermal fillers implanted may also benefit from or are candidates for monopolar rf skin tightening. this study examined the effect of rf treatment on various dermal filler substances. this is the second part of a two-part study. | 2006 | 16485274 |
| spontaneous gasping decreases intracranial pressure and improves cerebral perfusion in a pig model of ventricular fibrillation. | spontaneous gasping is associated with increased survival in animal models of cardiac arrest and in observational studies of humans. the potential beneficial effect of gasping on cerebral perfusion may underlie the observed survival benefit, but mechanisms remain unknown. | 2006 | 16494991 |
| acceleration of de novo bone formation following application of autogenous bone to particulated anorganic bovine material in vivo. | this prospective animal study examined the de novo bone formation following application of deproteinized bovine bone matrix (dbbm) with or without autogenous bone (ab) to osseous defects. | 2006 | 16504863 |
| evaluation of a modified piezoresistive technique and a water-capsule technique for direct and continuous measurement of intra-abdominal pressure in a porcine model. | intravesical pressure measurement is considered to be the gold standard for the assessment of intra-abdominal pressure. however, this method is indirect and depends on a physiologic bladder function. we evaluated a modified piezoresistive technique and a water-capsule technique for direct and continuous intra-abdominal pressure measurement. | 2006 | 16505660 |
| challenging the rationale of three sequential shocks for defibrillation. | the 2000 guidelines for cardiopulmonary resuscitation (cpr) recommend up to three sequential shocks for persistent ventricular fibrillation (vf). we hypothesized that the time consumed for repetitive rhythm analyses and recharging of the capacitor compromises the success of the second and third shock of each sequence. in 60 domestic pigs, vf was electrically induced and untreated for 7 min. after 1 min of cpr, which includes precordial compression and ventilation, up to three sequential shocks w ... | 2006 | 16517041 |
| antigenic properties and diagnostic potential of african swine fever virus protein pp62 expressed in insect cells. | african swine fever (asf) is an infectious and economically important disease of domestic pigs. the absence of vaccine renders the diagnostic test the only tool that can be used for the control of new outbreaks of the disease. at present, the enzyme-linked immunosorbent assay (elisa) test is the most useful method for large-scale asf serological studies, although false positives have been detected, mainly on poorly preserved sera. in order to improve the current diagnostic test available for asf ... | 2006 | 16517882 |
| collagen foil (tissufoil e) reduces the formation of adhesions when using polypropylene mesh for the repair of experimental abdominal wall defects. | polypropylene meshes (ppms) are routinely used in the treatment of incisional hernias to achieve a tension-free closure of the abdominal wall. severe adhesions are a common cause of intestinal obstruction, or even intestinal fistulas. using a porcine model, we investigated whether applying a collagen foil (cf) to the undersurface of a ppm will reduce adhesion formation. | 2006 | 16520931 |
| a new model of abdominal aortic aneurysm with gastric serosa patch: surgical technique and short-term evaluation. | the purpose of this work was to develop an abdominal aortic aneurysm (aaa) model that resembles human aneurysms with potential for further growth, patent collateral vessels, and a predictable tendency to rupture, and that can be used in the development of new endoprostheses and implant training. an infrarenal aaa model was created in five domestic swine using an autologous gastric serosal patch. pre- and postsurgical digital subtraction aortograms (dsa) were obtained to document the appearance a ... | 2006 | 16531367 |
| genetic analysis of ankamali pigs of india using microsatellite markers and their comparison with other domesticated indian pig types. | ankamali pigs, the domesticated native pigs of kerala province of india were genetically characterized using 23 fao recommended microsatellite markers and were compared with other native indian pig types and large white pigs. twenty-six blood samples were collected from genetically unrelated animals from their breeding tract and dna was isolated by standard procedure of phenol/chloroform. the genomic dna was amplified by polymerase chain reaction (pcr) at these 23 microsatellite loci, which were ... | 2006 | 16533367 |
| surgical technique for long-term cecal cannulation in the yucatan minipig (sus scrofa domestica). | measurements of standardized ileal digestibility yield more useful results than do those of fecal digestibility. to that end, cecal cannulation of the pig has been performed extensively in an attempt to model the digestive processes of humans. here we introduce a technique for the placement of a permanent cecal cannula with a silicon port that is larger in diameter than those previously described in the literature. a large lumen offers several advantages, most notably ease in collection of large ... | 2006 | 16539336 |
| hyperoxic ventilation increases the tolerance of acute normovolemic anemia in anesthetized pigs. | to investigate the impact of prophylactic hyperoxic ventilation with fio2 0.6 on the physiologic limit of acute normovolemic anemia. | 2006 | 16540965 |
| mandibular mechanics after osteotomy and distraction appliance placement i: postoperative mobility of the osteotomy site. | fixation at the osteotomy site for mandibular distraction osteogenesis (do) is probably not rigid, especially during mastication. micromotion may affect the course of do. this study aimed to measure the mobility of the fresh distractor-fixed osteotomy site in response to mastication and masticatory muscle stimulation. | 2006 | 16546640 |
| mandibular mechanics following osteotomy and appliance placement ii: bone strain on the body and condylar neck. | the purpose of this investigation was to determine if the mechanical environment of the mandible is changed by osteotomy and fixation, as assessed by the measurement of bone strain on the condylar neck and mandibular corpus. | 2006 | 16546641 |
| vascular closure stapler clip anastomosis decreases aortic cross-clamping time compared to interrupted nonabsorbable and running absorbable sutures in growing pigs. | the latest generation in titanium clip application systems, the vascular closure staples (vcs) system avoids intimal lesions and therefore minimizes the subsequent hyperplastic reaction, while at the same time enhancing distensibility and vascular growth. moreover, vcs clips allow the surgeon to perform vascular anastomosis easily and faster than conventional suture. this system may become the option of choice for vascular reconstruction in pediatric surgery where, as in the case of aortic and t ... | 2006 | 16378146 |
| comparison of invasive and less-invasive techniques of cardiac output measurement under different haemodynamic conditions in a pig model. | despite the introduction of various less-invasive concepts of cardiac output measurement, pulmonary arterial thermodilution is still the most common measurement technique. | 2006 | 16390561 |
| microwave ablation for atrial fibrillation: dose-response curves in the cardioplegia-arrested and beating heart. | microwave ablation has been used to replace the traditional incisions used in the surgical treatment of atrial fibrillation. however, dose-response curves have not been established in surgically relevant models. the purpose of this study was to develop dose-response curves for the flex 10 (guidant, inc) microwave device in both the acute cardioplegia-arrested heart and on the beating heart. | 2006 | 16368338 |
| a novel model to test accuracy and reproducibility of mdct scan protocols for coronary calcium in vivo. | we compared the accuracy and reliability of prospectively triggered, retrospectively ecg gated, and non-gated ct image reconstruction for measurements of coronary artery calcification (cac) in vivo using a novel animal model. | 2006 | 16374527 |
| fully mr-guided hepatic artery catheterization for selective drug delivery: a feasibility study in pigs. | to demonstrate the feasibility of hepatic catheterization for selective delivery of therapeutic agents using a clinical mri scanner for real-time image guidance. | 2006 | 16374883 |
| the epidemiology of human trichinellosis in china during 2000-2003. | the endemic foci of trichinellosis continue to be mainly located in the southwestern, the central and northeastern china. the seroepidemiological surveys of t. spiralis infection in humans were carried out in six provinces or municipals (p/m) of china during 2000-2003, the overall seroprevalence was 3.57%. from 2000 to 2003, 17 outbreaks of human trichinellosis, with 828 cases and 11 deaths, were recorded in 8 p/a of china. all of 11 deaths occurred in the southwestern china (1 case in sichuan, ... | 2006 | 16414006 |
| vascular injury caused by mechanical thrombectomy in porcine arteries: akónya eliminator device versus arrow-trerotola percutaneous thrombolytic device. | to compare vascular injuries induced by a nonrotational thrombectomy device equipped with an adjustable basket (the akónya eliminator [ake] device) and the arrow-trerotola percutaneous thrombolytic device (ptd) in porcine external iliac arteries (eias). | 2006 | 16415141 |
| the elephant knee joint: morphological and biomechanical considerations. | elephant limbs display unique morphological features which are related mainly to supporting the enormous body weight of the animal. in elephants, the knee joint plays important roles in weight bearing and locomotion, but anatomical data are sparse and lacking in functional analyses. in addition, the knee joint is affected frequently by arthrosis. here we examined structures of the knee joint by means of standard anatomical techniques in eight african (loxodonta africana) and three asian elephant ... | 2006 | 16420379 |
| feasibility of real-time magnetic resonance-guided stent-graft placement in a swine model of descending aortic dissection. | to evaluate the pre-clinical feasibility of real-time magnetic resonance imaging (rtmri) to guide stent-graft placement for experimental aortic dissection (ad) and to alleviate disadvantages of ionising radiation and nephrotoxic contrast media. endovascular stent-graft placement for thoracic aortic disease is usually performed under x-ray guidance. the feasibility of rtmri-guided stent-graft placement is currently not known. | 2006 | 16431874 |
| paradoxical effects of aurintricarboxylic acid and rg-13577: acute thrombosis and in-stent stenosis in a passive-coated stent. | to investigate if a platelet inhibitor (aurintricarboxylic acid [ata]) and a heparin-mimicking antagonist (rg-13577) of basic fibroblast growth factor 2 (bfgf2) could be combined as a stable compound and attached to conventional bare metal stents to hinder thrombus formation and inflammatory reactions of stenting. | 2006 | 16445329 |
| chronic antioxidant supplementation impairs coronary endothelial function and myocardial perfusion in normal pigs. | experimental studies have shown the beneficial effects of antioxidant supplementation on endothelial function in the presence of increased endogenous oxidative stress, whereas limited data are available under normal conditions. the present study tested the hypothesis that in normal pigs long-term antioxidants would have deleterious effects on the cardiovascular system. normal domestic pigs (v, n=6) were studied 12 weeks after dietary supplementation with vitamin e (100 iu/kg per day) and vitamin ... | 2006 | 16446399 |
| myocardial glycerol release, arrhythmias and hemodynamic instability during regional ischemia-reperfusion in an open chest pig model. | to develop cardioprotection against peri-operative myocardial ischemia-reperfusion injury, we need animal models where the local metabolism and blood flow are studied concomitantly with the global circulatory consequences during regional coronary occlusion. | 2006 | 16451157 |
| effects of an inspiratory impedance threshold device on blood pressure and short term survival in spontaneously breathing hypovolemic pigs. | the inspiratory impedance threshold device (itd) has been shown to improve hemodynamic variables and survival outcomes during cardiopulmonary resuscitation in animals and humans. we hypothesized that use of an itd, with a resistance of -10 cm h2o, will improve hemodynamics and short-term survival rates during hypovolemic hypotension in spontaneously breathing pigs. | 2006 | 16455176 |
| the characteristics of postcountershock pulseless electrical activity may indicate the outcome of cpr. | when ventricular fibrillation is cardioverted to pulseless electrical activity (pea), pea has been regarded as a non-resuscitatable rhythm. yet, recent reports and our earlier observations suggested otherwise. we therefore investigated outcomes after postcountershock pea, and aimed to develop a scoring system for outcome classification at the onset of initial postcountershock pea. | 2006 | 16459008 |
| the effect of pedicle expansion on pedicle morphology and biomechanical stability in the immature porcine spine. | biomechanical study in an animal model. | 2006 | 17047529 |
| temporary coronary artery occlusion during off-pump coronary artery bypass grafting with the new poloxamer p407 does not cause endothelial dysfunction in epicardial coronary arteries. | the aim of this study was to assess the efficacy of the novel reversible thermosensitive gel poloxamer 407 for occlusion of the coronary vessel necessary for minimally invasive operations and its effects on coronary endothelium. | 2006 | 17059936 |
| magnetic resonance imaging of the harderian gland in piglets. | the main purpose of the present study was to investigate the value and effectiveness of functional and morphological magnetic resonance imaging (mri), in order to assess the extent of brain injury in a hypoxic-ischaemic piglet model, and further to validate that the ischaemic injury was successfully induced. in this way, we also characterized the harderian gland. mri was performed at 1.5 t in anaesthetized piglets (n = 10, 12-36 h of age). magnetic resonance perfusion and diffusion imaging were ... | 2006 | 17062026 |
| changes in endocrine and neurochemical profiles in neonatal pigs prenatally exposed to increased maternal cortisol. | early life environmental factors are able to influence prenatal development and may cause structural and functional effects on hypothalamic-pituitary-adrenal (hpa) axis and neurotransmitter systems in the offspring. these effects seem to be species specific and may depend on the period of gestation when the factors are effective. elevated maternal cortisol levels are assumed to play a crucial role as a programming factor during prenatal development. thus, the present study was performed in order ... | 2006 | 17065404 |
| effect of hypercapnia on cerebral blood flow and blood volume in pigs studied by positron emission tomography. | pigs are increasingly used as in vivo models in neuroscience, including studies using positron emission tomography. during anesthesia, cerebral blood flow (cbf) and cerebral blood volume (cbv) are mainly regulated by the partial pressure of co2 (pco2) in arterial blood. we sought to determine the effects of increased arterial pco2 (hypercapnia) on cbf and cbv in anesthetized domestic pigs. we anesthetized 4 pigs and manipulated the tidal volume of the ventilator to different pco2 levels. baselin ... | 2006 | 17069026 |
| the effects of ropivacaine at clinically relevant doses on myocardial ischemia in pigs. | a major risk associated with bupivacaine during myocardial ischemia is ventricular fibrillation. we investigated the influence of ropivacaine on cardiac contractility and the propensity to ventricular fibrillation before and after myocardial ischemia in a placebo-controlled pig study. anesthetized domestic pigs were administered 1 mg.kg(-1) of ropivacaine intravenously over 1 min and then 0.03 mg.kg(-1).min(-1) as a 30-min infusion, or saline. the following endpoints were measured before and aft ... | 2006 | 17072705 |
| a paleolithic diet confers higher insulin sensitivity, lower c-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs. | a paleolithic diet has been suggested to be more in concordance with human evolutionary legacy than a cereal based diet. this might explain the lower incidence among hunter-gatherers of diseases of affluence such as type 2 diabetes, obesity and cardiovascular disease. the aim of this study was to experimentally study the long-term effect of a paleolithic diet on risk factors for these diseases in domestic pigs. we examined glucose tolerance, post-challenge insulin response, plasma c-reactive pro ... | 2006 | 17081292 |
| modification of the arterial anastomotic technique improves survival in porcine single lung transplant model. | lung transplantation is a valuable therapeutic option for selected patients with end-stage pulmonary disease. however, this treatment is complicated by ischaemia-reperfusion injury (iri) of the lung in 10-20% of the recipients. we developed an unilateral porcine lung transplant model to study iri and describe our experience with two different arterial anastomotic techniques. | 2006 | 17017708 |
| [methods for investigating trichinella infections in domestic and wild animals]. | trichinellosis is an important parasitic zoonosis that is caused by the intracellular nematode trichinella spp.. infection of humans occurs through consumption of raw (or undercooked) meat containing infectious larvae. in europe, meat from pork, horse, and wild boar have been identified as most important sources of trichinella infections in humans. in switzerland, both the domestic pig and wild boar population are considered free of trichinella. conversely, swiss foxes, lynxs and recently a wolf ... | 2006 | 17024975 |
| parenteral vaccination of domestic pigs with brucella abortus strain rb51. | to determine the immunogenicity and efficacy of brucella abortus strain rb51 (srb51) as a vaccine in domestic pigs. | 2006 | 17014337 |
| in vitro development of cloned embryos derived from miniature pig somatic cells after activation by ultrasound stimulation. | the present study was carried out to examine the activation and development of cloned embryos produced by transferring miniature pig somatic cells into enucleated farm pig oocytes after exposing to ultrasound. the rates of the pronucleus-like structure formation and polar body-like structure extrusion in embryos exposed to ultrasound did not differ from those applied electric pulses. although there was no significant difference in the blastocyst formation rates between different activation metho ... | 2006 | 17009892 |
| isolation and characterization of novel h3n1 swine influenza viruses from pigs with respiratory diseases in korea. | pigs can play an important role in the genetic reassortment of influenza viruses and as a reservoir for another lineage of influenza viruses that have the ability to reassort and be transmitted between species. in march and april 2006, novel h3n1 influenza a viruses were isolated from pigs with respiratory diseases at two different commercial swine farms in korea. genetic and phylogenetic analyses of the sequences of all eight viral rna segments showed that the novel h3n1 swine influenza viruses ... | 2006 | 16928961 |
| the uncoupling protein 1 gene (ucp1) is disrupted in the pig lineage: a genetic explanation for poor thermoregulation in piglets. | piglets appear to lack brown adipose tissue, a specific type of fat that is essential for nonshivering thermogenesis in mammals, and they rely on shivering as the main mechanism for thermoregulation. here we provide a genetic explanation for the poor thermoregulation in pigs as we demonstrate that the gene for uncoupling protein 1 (ucp1) was disrupted in the pig lineage. ucp1 is exclusively expressed in brown adipose tissue and plays a crucial role for thermogenesis by uncoupling oxidative phosp ... | 2006 | 16933999 |
| in vivo cardiovascular catheterization under real-time mri guidance. | to test the hypothesis that cardiac and coronary catheterization can be successfully performed under real-time mr guidance using a conventional x-ray angiographic catheter. | 2006 | 16941633 |
| characterization of hepatic drug-metabolizing activities of bama miniature pigs (sus scrofa domestica): comparison with human enzyme analogs. | we used various substrates and selective inhibitors of human cytochrome p450 (cyp) isozymes as probes to study the metabolism of liver microsomes from chinese bama miniature pigs. nifedipine oxidation (nod) and testosterone 6beta-hydroxylation (6beta-oht) activities were similar between human liver microsomes and those from bama miniature pigs. however, compared with those from humans, liver microsomes from bama miniature pigs showed decreased phenacetin o-deethylation, coumarin 7-hydroxylation, ... | 2006 | 16941956 |
| bladder augmentation with acellular dermal biomatrix in a diseased animal model. | the use of bowel for bladder augmentation is associated with many complications. we have reported that acellular dermal biomatrix can be used successfully for directing the regeneration of each key bladder wall element in healthy domestic pigs. before proposing that this material should be used in the human setting a final set of experiments using this scaffold to replace diseased bladder wall is necessary. we determined if acellular dermal biomatrix can be used to replace diseased bladder wall. ... | 2006 | 16945628 |
| inhibition of dipeptidyl-peptidase iv does not increase circulating igf-1 concentrations in growing pigs. | the enzyme dipeptidyl peptidase-iv (dpp-iv) inactivates a variety of bioactive peptides, including glucagon-like peptide-1 (glp-1) and growth hormone releasing hormone (ghrh). inhibiting dpp-iv in order to increase circulating glp-1 is of interest as a treatment for type ii diabetes. inactivation of dpp-iv may also increase circulating ghrh, potentially enhancing growth in domestic animals. to test the hypothesis that inhibition of dpp-iv activity will influence the growth hormone/ igf-1 axis, g ... | 2006 | 16946406 |
| torque teno virus (ttv) is highly prevalent in the european wild boar (sus scrofa). | the present study represents the first survey of torque teno virus (ttv) prevalence in european wild boar (sus scrofa). the prevalence of two distinct ttv genogroups in 178 spanish wild boar sera from different geographic regions, management conditions, gender and age was determined by a nested pcr method. the overall prevalence of ttv genogroups was 84% (58% for genogroup 1 and 66% for genogroup 2), and differences between genogroup prevalence were observed depending on the geographical region ... | 2006 | 16959441 |
| season controlled reproduction of undomesticated animals. | the following article is a summary of research on the influence of season on the reproductive processes in undomesticated animals. the results presented below show: a/ an annual hormonal profile of domestic pig and wild boar crossbreed and the antioxidant blood system in the different seasons, b/ the possibility of gonadptropic hormone stimulation in chinchillas which are in diestrus or infertile, c/ the possibility of using bison's semen (collected post mortem from the epididymis) for cryoconse ... | 2006 | 16967095 |
| safety and efficacy of bioabsorbable magnesium alloy stents in porcine coronary arteries. | we aimed to determine the safety and efficacy of biobasorbable magnesium alloy stents in porcine coronary arteries. bioabsorbable magnesium stents carry the potential to overcome the limitations posed by permanent metallic stents such as chronic inflammation, late stent thrombosis, prolonged antiplatelet therapy, and artifacts when imaged by multislice-computed tomography or magnetic resonance imaging. | 2006 | 16969879 |
| a simple dsa method to detect air contamination during co2 venous studies. | the use of co2 as a contrast agent has increased significantly for visualization of the central veins, inferior vena cava, and portal vein. the most serious complication associated with co2 studies is air contamination. we evaluated a simple digital subtraction angiogram (dsa) method to detect air contamination during co2 venous studies. after injections of 5, 10, and 20 cm3 of co2 and 5 cm3 of air into the inferior vena cavas of five domestic swine in the left lateral decubitus position, a dsa ... | 2006 | 16604404 |
| volumetric coronary angiography using the 256-detector row computed tomography scanner: comparison in vivo and in vitro with porcine models. | to investigate the feasibility of volumetric cine imaging in human cardiac studies by comparing in vivo and in vitro coronary angiography using a 256-detector row computed tomography (ct) without ecg gating. | 2006 | 16604966 |
| isolation and characterization of a sagiyama virus from domestic pigs. | in 2002, a strain of sagiyama virus (sagv) designated ml/taiwan/02 was isolated from farmed pigs in taiwan. the nsp1 and e1 gene sequences of the ml/taiwan/02 strain shared 98.6 and 96.7% homology, respectively, with corresponding genes of a japanese strain of sagv. nucleotide and amino acid sequence comparison revealed this strain of sagv to be most closely related to getah virus, as opposed to its current classification as a subtype of ross river virus. to investigate the seroprevalence of sag ... | 2006 | 16617695 |
| absorption of the nerve agent vx (o-ethyl-s-[2(di-isopropylamino)ethyl] methyl phosphonothioate) through pig, human and guinea pig skin in vitro. | the physico-chemical properties of vx make the skin the most likely route of absorption into the human body. the development of effective medical countermeasures against such percutaneous threat agents relies on the use of appropriate animal models, as the inherent toxicity of nerve agents precludes the use of human volunteers. previous studies have characterised the mechanism of nerve agent toxicity in rodent models, however, it is generally accepted that one of the most appropriate animal mode ... | 2006 | 16904285 |
| scaffold-free, engineered porcine cartilage construct for cartilage defect repair--in vitro and in vivo study. | this study introduces an implantable scaffold-free (sf) cartilage tissue construct that is composed of chondrocytes and their self-produced extracellular matrix (ecm). chondrocytes were isolated from the articular cartilages from knees of domestic pigs (2-week old) and monolayer-cultured for 3-4 days in dulbecco's modified eagle's medium supplemented with 10% fetal calf serum and 50 microg/ml of ascorbic acid. briefly treated with 0.25% trypsin-ethylenediaminetetraacetic acid (edta), an intact c ... | 2006 | 16911312 |
| phenotype-based identification of host genes required for replication of african swine fever virus. | african swine fever virus (asfv) produces a fatal acute hemorrhagic fever in domesticated pigs that potentially is a worldwide economic threat. using an expressed sequence tag (est) library-based antisense method of random gene inactivation and a phenotypic screen for limitation of asfv replication in cultured human cells, we identified six host genes whose cellular functions are required by asfv. these included three loci, bat3 (hla-b-associated transcript 3), c1qtnf (c1q and tumor necrosis fac ... | 2006 | 16912318 |
| mitochondrial haplotypes of european wild boars with 2n = 36 are closely related to those of european domestic pigs with 2n = 38. | wild boars from western europe have a 2n = 36 karyotype, in contrast to a karyotype of 2n = 38 in wild boars from central europe and asia and in all domestic pigs. the phylogenetic status of this wild boar population is unclear, and it is not known if it has contributed to pig domestication. we have now sequenced the mtdna control region from 30 european wild boars (22 with a confirmed 2n = 36 karyotype) and six asian wild boars (two hainan and four dongbei wild boars) to address this question. ... | 2006 | 16978174 |
| the responses of growing pigs to a chronic-intermittent stress treatment. | many of the stressor treatments used in animal models of depression have parallels in the normal experiences of domestic pigs. the experiment described here aimed to assess whether a chronic-intermittent stress regime caused behavioural or physiological changes, indicative of depression, in domestic pigs. ten juvenile male pigs were exposed to a social and environmental stress regime. over the stressor period, weight gain was significantly lower in test pigs than in control pigs. stress treatmen ... | 2006 | 16982073 |
| tissue anchors for transmural gut-wall apposition. | with the development of notes (natural orifice transluminal endoscopic surgery) and efforts to advance gastric reduction surgery, alternatives for robust tissue apposition apart from suturing and current mucosal clipping devices may be valuable. | 2006 | 16996353 |
| burn depths evaluation based on active dynamic ir thermal imaging--a preliminary study. | proper diagnostic assessment of burn wound depth is of the highest importance in selecting the mode of burn wound treatment. several diagnostic methods--clinical and histopathological evaluation, as well as methods employing ir imaging--static thermography and active dynamic thermography (adt)--are compared on the basis of in vivo experiments conducted on three domestic pigs (23 burn wounds). adt is presented here as a new, reliable and quantitative method of assessing burn wound depth on the ba ... | 2006 | 16997482 |
| current trends in safety assurance for tissue grafts used in burn treatment. | the author presents a summary of current safety standards for allogeneic and xenogeneic biological skin grafts. the fundamental document relevant to allogeneic transplants, establishing the minimal level of safety guaranteed in european union states, is the european parliament and council directive (2004/23/ec) from march 31st 2004. this directive determines that grafts will be prepared by a licensed or accredited tissue bank, and that this arrangement must be put in place by the member states w ... | 2006 | 16999268 |
| efficacy and safety of right and left atrial ablations on the beating heart with irrigated bipolar radiofrequency energy: a long-term animal study. | the cox maze procedure is the most effective surgical treatment for atrial fibrillation; however, its complexity has limited its clinical utility. the purpose of this study was to simplify the procedure by using an irrigated bipolar radiofrequency ablation device on the beating heart without cardiopulmonary bypass. | 2006 | 17000297 |
| genetic diversity in wild (sus scrofa scrofa) and domestic (sus scrofa domestica) pigs and their hybrids based on polymorphism of a fragment of the d-loop region in the mitochondrial dna. | we examined the variation in mitochondrial dna by sequencing the d-loop region in wild and domestic (large-white breed) pigs, in hybrids between domestic and wild pigs, and in monteiro pigs. a d-loop fragment of approximately 330 bp was amplified by pcr. sequencing of dna amplicons identified haplotypes previously described as european and asian types. monteiro pigs and wild pigs had european haplotypes and domestic pigs had both european and asian haplotypes. | 2006 | 17183469 |
| running speed in mammals increases with muscle n-6 polyunsaturated fatty acid content. | polyunsaturated fatty acids (pufas) are important dietary components that mammals cannot synthesize de novo. beneficial effects of pufas, in particular of the n-3 class, for certain aspects of animal and human health (e.g., cardiovascular function) are well known. several observations suggest, however, that pufas may also affect the performance of skeletal muscles in vertebrates. for instance, it has been shown that experimentally n-6 pufa-enriched diets increase the maximum swimming speed in sa ... | 2006 | 17183696 |
| radiofrequency ablation of normal lungs after pulmonary artery embolization with use of degradable starch microspheres: results in a porcine model. | the present study was performed to evaluate the effect of pulmonary artery embolization on radiofrequency (rf) ablation of normal porcine lungs. | 2006 | 17185698 |
| different fecal shedding patterns of two common strains of hepatitis e virus at three japanese swine farms. | zoonotic infections caused by eating the meat of deer, wild boar, and pig have been suggested in japan, a country that is not epidemic for hepatitis e caused by hepatitis e virus (hev). this virus is widely spread in domestic pigs in both epidemic and non-epidemic countries. we studied fecal hev shedding patterns on three japanese farms that had two common genotype iii hev strains. two of the three farms had high shedding peaks (75% and 100%) in pigs 1-3 months of age, suggesting that these anim ... | 2006 | 17172388 |
| implant-supported prosthetic applications upon development of children and adolescents: a pilot study in pigs. | the purpose of this study is the investigation of the application of implant-supported prosthetic restorations using 2 implants supporting a fixed prosthesis during the physical growth and the development period of growing pigs. | 2006 | 17172960 |
| real-time detection and alerting for acute st-segment elevation myocardial ischemia using an implantable, high-fidelity, intracardiac electrogram monitoring system with long-range telemetry in an ambulatory porcine model. | the purpose of this study was to evaluate feasibility of using real-time, high-fidelity, intracardiac electrogram monitoring from a permanently implantable ischemia detection system (iids), with long-range telemetry capability to detect st-segment shifts associated with acute or subacute coronary occlusion in a porcine model. | 2006 | 17161264 |
| systematics and epidemiology of trichinella. | in this review, we describe the current knowledge on the systematics, ecology and epidemiology of trichinella and trichinellosis, and the impact of recent research discoveries on the understanding of this zoonosis. the epidemiology of this zoonosis has experienced important changes over the past two decades, especially with regard to the importance of the sylvatic cycle and the sylvatic species. outbreaks of trichinellosis due to trichinella spiralis from domestic swine, while still frequent, in ... | 2006 | 17134656 |
| a novel method of endoscopic submucosal dissection with blunt abrasion by submucosal injection of sodium carboxymethylcellulose: an animal preliminary study. | endoscopic submucosal dissection (esd), particularly the process of submucosal incision with a knife, is technically difficult and carries a high risk of perforation. submucosal injection of a viscous substance, eg, jelly, obviates the need of submucosal incision with a knife. sodium carboxymethylcellulose (scmc), known as cellulose gum, is highly viscous when dissolved in water. | 2006 | 17140905 |
| pharmacologic manipulation of the porcine ureter: acute impact of topical drugs on ureteral diameter and peristaltic activity. | intraluminal application of pharmacologic agents for acute ureteral dilation may facilitate difficult ureteroscopy. we characterized the in-vivo effects of intraluminal application of verapamil and theophylline on ureteral peristalsis and diameter in a porcine model. | 2006 | 17144869 |
| noninfectious complications due to vascular access ports (vaps) in yucatan minipigs (sus scrofa domestica). | vascular access ports (vaps) for studies requiring intermittent or continuous infusion and frequent sampling are well accepted and widely used in large animal species. however, the use of medical devices such as vaps to facilitate sample collection can lead to complications. noninfectious complications of vap implantation can result from thrombotic or mechanical obstructions, other mechanical problems, and animal-associated complications. to facilitate our research, we surgically implanted vaps ... | 2006 | 17089988 |
| the use of a micro-bubble contrast agent to allow visualization of the biliary tree. | micro-bubble contrast agents have been used as contrast agents in the vascular system to allow visualization of blood flow by ultrasound. we examined the use of this type of contrast agent for visualization of bile duct by ultrasound. a laparotomy was performed on a domestic farm pig and the common bile duct was cannulated with a 20 gauge catheter. the contrast agent, perflutren lipid microspheres (definity), was injected in different dilutions. sonographic images were obtained by scanning direc ... | 2006 | 17100724 |
| bilateral intra-annular spinal compressive stresses in vivo. | the purpose of this pilot study was to determine if compressive stresses in the annulus of the intervertebral disc vary with activity in a quadruped and are affected by treatment with an implant. pilot in vivo tests were conducted on skeletally immature domestic pigs (approved by iacuc). one pair of sensors was implanted within the annulus of t10-11, and the second pair at t8-9. a staple was them implanted across the right side of t8-9. wires were routed subcutaneously and exited at the dorsal c ... | 2006 | 17108458 |
| [the histogenesis of interrenal primordium of the adrenal gland in pig (sus domestica)]. | using light, electron microscopy and cytochemistry, the early (embryonic week 4-8) stages of adrenal gland (ag) development were studied in domestic pig. the interrelations between the cells of the fetal cortex (fc) and chromaffin cells (cc) were traced. at week 5, ag primordium is represented by fc, which consists of the epithelioid cells, with the ingrowing neural cords containing cc islets. starting at the early embryonic period and up to fetal period, cc and interrenal cells of fc are closel ... | 2006 | 17111663 |
| analysis of expressed sequence tags from skeletal muscle-specific cdna library of chinese native xiang pig. | a longissimus dorsi muscle cdna library of xiang pig was constructed, and 131 randomly isolated clones were sequenced in this study. the results of bioinformatics analysis showed that 131 ests represented 109 unique clones sequences, of which 99 showed homology to previously identified genes in humans or other mammals, 3 matched other uncharacterized expressed sequence tags (ests), and 7 showed no significant matches to sequences already present in dna databases. no protein matches were found fo ... | 2006 | 17112969 |
| intrathoracic pressure regulation for intracranial pressure management in normovolemic and hypovolemic pigs. | to evaluate the potential to use subatmospheric intrathoracic pressure to regulate intracranial pressure (icp) in normovolemic and hypovolemic animals, we tested the hypothesis that mechanical devices designed to reduce intrathoracic pressure will decrease icp in a dose-related manner. an inspiratory impedance threshold device was used in spontaneously breathing animals and an intrathoracic pressure regulator was attached to a positive pressure ventilator and used in apneic animals: both devices ... | 2006 | 17114984 |
| evaluation of males spermiogram in domestic pigs. | a microscopic assessment was used to estimate sperm morphological structure in 405 ejaculates from 70 boars according to blom classification. the classification of spermiogram quality according to a new 6-degree scale was also established. we found, that male spermiograms in domestic pigs were characterized by a large variability both between and within breeds. the estimation of semen quality, only with regard to the mean frequency of occurrence of particular morphological forms of spermatozoa, ... | 2006 | 17220947 |
| sperm morphology of cattle and domestic pigs. | sperm morphology was evaluated (using blom classification) in 44 ejaculates of 11 bulls and 44 ejaculates of 11 boars. significant differences in sperm morphology were found between bulls and boars. in addition, the correlations between frequency of morphological changes and morphometrical traits of boar spermatozoa were demonstrated. more morphological anomalies of spermatozoa were recorded in ejaculates containing longer spermatozoa. | 2006 | 17220948 |
| structure traits of longissimus lumborum muscle in wild boar/domestic pig hybrids. | the structure of musculus longissimus lumborum (m.l.l.) was evaluated with respect to proportion of three muscle fiber types and their diameters, in gilts and barrows of wild boar/domestic pig hybrids. the experiment was carried out on 29 hybrids (21 barrows and 8 gilts) which originated from crossing duroc sows with wild boar (sus scrofa ferus). the diameter of the "red" fibres in barrows was 48.42 microm, significantly greater than in gilts--43.71 microm. the diameters of the remaining two typ ... | 2006 | 17220008 |
| evaluation of microporous polysaccharide hemospheres for parenchymal hemostasis during laparoscopic partial nephrectomy in the porcine model. | we evaluated the efficacy of microporous polysaccharide hemospheres (mph) for parenchymal hemostasis during laparoscopic partial nephrectomy (lpn) in the porcine model. | 2006 | 17212884 |
| retroposed elements as archives for the evolutionary history of placental mammals. | reconstruction of the placental mammalian (eutherian) evolutionary tree has undergone diverse revisions, and numerous aspects remain hotly debated. initial hierarchical divisions based on morphology contained many misgroupings due to features that evolved independently by similar selection processes. molecular analyses corrected many of these misgroupings and the superordinal hierarchy of placental mammals was recently assembled into four clades. however, long or rapid evolutionary periods, as w ... | 2006 | 16515367 |
| collagenase promotes the cellular responses to injury and wound healing in vivo. | this study focuses on the growth-promoting and migration-enhancing role that clostridial collagenase plays in vitro and in vivo. | 2005 | 16921413 |
| population structure in ascaris suum (nematoda) among domestic swine in denmark as measured by whole genome dna fingerprinting. | we here analyze the population structure in the pig roundworm, ascaris suum, among domestic pigs in denmark using a whole-genome dna fingerprinting technique, "amplified fragment length polymorphism" (aflp) analysis. with these data, we can extract absolute gene frequency variance components and g-statistics for 135 independent nucleotide polymorphisms. the average proportion of total variance partitioned between jutland and zealand is less than 3% of the total variance, implying no restriction ... | 2005 | 16970605 |
| aortic cannulation and cardiopulmonary bypass independently produce selective brain lesions in pig. | whether cardiopulmonary bypass alone or together with the manipulation of the aorta produce neurological complication remains controversial. using a domestic pig model of cardiopulmonary bypass, we investigated the immediate effects of aortic cannulation and cardiopulmonary bypass on neuronal injury in different brain regions. we compared the presence of neuronal injury in three experimental groups: non-operated controls (n = 3); operated controls with aortic cannulation without cardiopulmonary ... | 2005 | 16463582 |
| a potent and selective tacrine analog--biomembrane permeation and physicochemical characterization. | cholinesterase inhibitors have been used for years in treatment of alzheimer's disease (ad). tacrine is the first acetylcholinesterase inhibitor approved for treating ad by the regulatory agencies around the world. unfortunately, a number of studies have shown tacrine to be associated with some severe side effects, including hepatotoxicity. these adverse effects may be attributed to its poor selectivity for acetylcholinesterase and have thus necessitated the research and development of more sele ... | 2005 | 16370182 |
| multiple-electrode radiofrequency ablation: simultaneous production of separate zones of coagulation in an in vivo porcine liver model. | a multiple-electrode radiofrequency (rf) system was developed based on switching between electrodes that allows for the simultaneous use of as many as three electrically independent electrodes. the purpose of this study was to determine if each multiple-electrode ablation zone is identical to an ablation zone created with conventional single-electrode mode. | 2005 | 16371542 |
| a new animal model of choroidal neovascularization. | the purpose of this study was to evaluate the ability of different methods to induce choroidal neovascularization (cnv) in the domestic pig. | 2005 | 16396647 |
| sequence analysis of proviral dna of porcine endogenous retroviruses. | among all species analyzed, the domestic pig seems to be the most appropriate organ donor for xenotransplantation. porcine endogenous retroviruses (pervs) are present in genomes of all pigs and are capable of infecting human cells in vitro thus posing a serious threat for xenotransplantation procedures. despite the abundant distribution of pervs integrated with porcine genome, the majority of perv proviral dna is not capable of expressing viral proteins unless seriously mutated. the aim of the s ... | 2005 | 16387182 |
| [background of recent je vaccine issues]. | in japan, more than 5,000 patients were reported in 1950, and there have been less than 10 cases annually since 1992. however, japanese encephalitis virus caused of japanese encephalitis (je) are still existed highly and widely in the country, reported by national institute of infectious diseases with serological examination among domestic pig population. je immunization had been provided to children as category 1 routine immunization in japan. however, the ministry of health, labor and welfare ... | 2005 | 16557017 |
| porcine circovirus diseases. | porcine circovirus type 2 (pcv2) is a member of the family circoviridae, a recently established virus family composed of small, non-enveloped viruses, with a circular, single-stranded dna genome. pcv2, which is found all over the world in the domestic pig and probably the wild boar, has been recently associated with a number of disease syndromes, which have been collectively named porcine circovirus diseases (pcvd). postweaning multisystemic wasting syndrome (pmws), porcine dermatitis and nephro ... | 2005 | 16583778 |
| the effect of variable release kinetics on paclitaxel efficacy from a drug eluting stent in a porcine model. | aims: paclitaxel is a potent and effective inhibitor of neointimal proliferation after coronary stenting. the conor stent loaded with paclitaxel can be programmed with multi-parameter matrix of dose, temporal release profiles and release pathways. the aim of this study was to determine the most efficacious dose and release pattern of paclitaxel in a porcine model and parallels the pisces trial.methods: 32 farm pigs were implanted with conor stents loaded with 10 or 30 microg of paclitaxel with, ... | 2005 | 19758908 |
| [the morphology of domestic pigs in middle europe during the 16th to 18th century]. | the external of swine in mideurope during the 16th to 18th century will be described based on a few publications and various pictures (120). long legged, slender, bristly pigs with long snouts and prick ears dominated during the 16th century, sometimes, however, compact animals with shorter snouts and larger prick or lope ears have been depicted (tab. 1). during the 17th century no correct descriptions of the pigs are avaiable. the pictures show similar types as in the century before (tab. 1). i ... | 2005 | 16366038 |
| dose mapping of porcine coronary arteries using an optical fiber dosimeter. | this study is about the measurement of radiation dose contribution to the coronary arteries during intravascular brachytherapy with beta and gamma emitters utilizing in vivo optical fiber dosimeters. | 2005 | 16326378 |
| agrarian diet and diseases of affluence--do evolutionary novel dietary lectins cause leptin resistance? | the global pattern of varying prevalence of diseases of affluence, such as obesity, cardiovascular disease and diabetes, suggests that some environmental factor specific to agrarian societies could initiate these diseases. | 2005 | 16336696 |
| [sequence variation of tyr exon 1 and origin of pigs]. | to investigate the origin and genetic diversity of domestic pigs, the porcine tyr exon 1 in 36 individuals from 12 chinese indigenous breeds, three european breeds, eight chinese wild boars and two vietnamese wild boars was sequenced. sequence analysis revealed six synonymous mutations, and all the sequences could be sorted into 4 haplotypes. combining with the published sequences, we constructed a reduced median network (rm network), in which tyr*2 was a haplotype dominated by european domestic ... | 2005 | 16257898 |